Benign neoplasm: Ribs, sternum and clavicle

CD2_BENIGN_RIBS_STERNUM_CLAVICLE

bone neoplasm: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D16.7& Hospital discharge: ICD-9 — 2133 Hospital discharge: ICD-8 — 21302 Cause of death: ICD-10 — D16.7& Cause of death: ICD-9 — 2133 Cause of death: ICD-8 — 21302 2 out of 7 registries used, show all original rules.	84
4. Check minimum number of events None	84
5. Include endpoints None	84
6. Filter based on genotype QC (FinnGen only)	82

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D16
Name in latin: Neoplasma benignum costae, sterni sive claviculae

NAME	CD2_BENIGN_RIBS_STERNUM_CLAVICLE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D167
HD_ICD_9	2133
HD_ICD_8	21302
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D167
COD_ICD_9	2133
COD_ICD_8	21302
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Ribs, sternum and clavicle based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	837	393	438
Only index persons	695	347	348
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	34.51	37.27	32.09
Only index persons	30.43	34.20	26.66

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	82	42	40
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	41.06	44.26	37.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
84: Matched controls
840

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D16.7

ICD-10 Finland

Benign neoplasm: Ribs, sternum and clavicle

+∞

56.9

21302

ICD-8 Finland

Benign neoplasm of bone and cartilage, Costae, sterni, claviculae

+∞

27.6

2133A

ICD-9 Finland

Benign neoplasm of bone and articular cartilage, Ribs, sternum and clavicle

+∞

11.7

GAE06

NOMESCO Finland

Excision of lesion of chest wall

75.3

6.5

D48.0

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage

29.1

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

106

2.31

2.53

1.3

22.20

11.76

u/ml

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

113

2.14

2.16

1.4

1.3

9.11

38.49

iu/ml

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

3.95

1.97

1.7

1.3

—

(4200892) Spirometry reversibility

2.49

1.79

1.5

1.3

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

3.51

1.78

1.7

1.3

—

1.46

—

(3026493) Urate [Moles/volume] in Serum or Plasma

181

1.82

1.70

1.8

2.9

294.77

5273.80

umol/l

1.07

157

(3042936) Bacteria identified in Isolate by Culture

1.99

1.57

1.1

2.7

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

3.47

1.54

1.8

1.3

—

(3026008) Bacteria identified in Urine by Culture

195

1.74

1.53

2.6

3.0

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

153

1.80

1.51

1.2

0.97

0.66

u/ml

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

121

1.86

1.48

1.2

1.5

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

401

1.61

1.29

8.4

10.4

3.54

4.15

e9/l

1.60

356

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

515

1.67

1.26

4.6

4.3

15.11

14.89

pmol/l

0.33

472

(40760892) CBC W Ordered Manual Differential panel - Blood

326

1.58

1.22

8.0

7.3

—

(36660697) Celiac disease serology panel - Serum

2.03

1.18

1.1

—

(3022217) INR in Platelet poor plasma by Coagulation assay

316

1.51

1.03

12.5

14.0

1.06

1.25

inr

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

404

1.51

1.03

3.1

6.3

6.62

6.65

mmol/l

0.04

376

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

1.75

1.02

4.6

4.8

36.20

33.69

—

(40768797) Stomach Pathology biopsy report

1.70

0.95

1.6

1.2

—

(40768443) Skin Pathology biopsy report

2.23

0.93

1.2

1.3

—

(3044889) 12 lead EKG panel

470

0.68

0.92

4.9

3.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

293

1.47

0.92

2.4

3.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.00

0.92

1.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

148

1.56

0.89

2.2

3.0

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.82

0.85

2.4

124.25

130.43

ng/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

196

1.47

0.81

3.3

3.8

1.47

9.02

mg/mmol

2.28

126

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

671

1.67

0.80

15.3

14.7

19.84

20.77

mg/l

0.08

511

(3000991) Gas panel - Venous blood

1.75

0.78

4.1

11.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.25

0.77

2.4

2.5

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

542

1.46

0.76

9.2

7.5

82.63

78.01

u/l

0.32

511

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

2.15

0.76

1.8

3.8

—

(3044640) Blood type and Crossmatch panel - Blood

209

1.43

0.73

2.3

2.8

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

275

1.40

0.72

3.3

5.0

36.16

36.05

g/l

0.04

261

(3012516) Albumin [Mass/volume] in Urine

183

1.44

0.70

2.9

3.2

11.59

63.27

mg/l

2.08

114

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.90

0.69

2.2

2.0

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.90

0.69

1.6

1.4

—

(3013707) Erythrocyte sedimentation rate by Westergren method

526

1.41

0.68

5.6

4.0

11.28

11.33

mm/h

0.01

479

(3019225) pH of Specimen

1.63

0.66

3.8

3.5

—

(3031040) Bacteria [#/volume] in Urine by Automated count

438

1.35

0.62

5.3

4.3

—

100.00

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

626

1.45

0.61

5.7

5.0

2.02

1.85

mu/l

0.39

575

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.56

0.61

2.3

9.0

102.83

103.86

mmol/l

0.39

(3025941) Bacteria identified in Stool by Culture

1.62

0.55

1.7

1.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

445

1.31

0.52

4.9

4.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

102

1.45

0.51

1.9

2.2

—

(1761868) Lipid panel - Serum or Plasma

249

0.74

0.50

2.7

2.9

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.44

0.47

2.5

2.3

2.79

2.36

g/l

2.20

(3011397) Hemoglobin [Presence] in Urine by Test strip

141

1.35

0.45

4.2

3.7

—

(40768804) Tissue Pathology biopsy report

264

1.28

0.44

2.1

2.0

—

(3020891) Body temperature

1.65

0.44

2.2

4.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

245

1.28

0.43

3.7

4.1

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.39

0.42

1.9

1.8

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.41

0.0

1.5

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.40

0.0

1.5

—

(3003694) ABO and Rh group [Type] in Blood

178

0.74

0.39

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

240

1.25

0.37

4.0

3.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.39

0.36

12.3

7.9

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.36

0.34

5.7

10.2

0.85

0.76

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.33

0.34

5.7

10.0

2.23

1.77

—

(40761536) Microorganisms panel - Urine sediment

1.41

0.32

3.1

4.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.41

0.32

1.1

2.6

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.30

0.31

4.4

9.9

1.51

1.34

mmol/l

—

(3013512) EKG study

207

1.22

0.29

3.0

4.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

660

1.25

0.27

4.1

4.7

4.82

4.65

mmol/l

0.65

605

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.26

0.26

1.6

1.9

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.22

0.26

1.6

2.0

—

(3002256) Pathology report gross observation

1.22

0.26

1.0

1.2

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.37

0.24

1.0

2.1

—

(3022145) Colonoscopy Study observation

1.29

0.24

1.5

1.3

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.34

0.23

1.0

5.3

134.40

127.61

g/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

261

1.17

0.22

2.3

2.1

101.82

97.18

pmol/l

0.24

133

(40758558) Short blood count panel - Blood

176

0.82

0.22

5.5

7.4

—

(40761511) CBC panel - Blood by Automated count

696

1.24

0.22

16.7

13.0

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.20

0.22

1.0

1.3

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

3.5

—

59.17

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.0

—

285.50

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

0.21

0.0

3.0

—

421.10

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

4.9

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.21

0.0

1.6

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.4

—

3.24

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.3

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

2.6

—

89.61

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.3

—

106.25

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.3

—

4.08

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

636

0.85

0.21

6.3

5.8

39.89

40.14

mmol/mol

0.07

596

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.5

—

66.08

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

655

1.20

0.21

4.1

4.7

1.57

1.46

mmol/l

0.95

597

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.2

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.20

0.0

4.0

—

22.21

—

(3007164) IgA [Mass/volume] in Serum or Plasma

147

1.20

0.20

1.2

1.4

3.06

2.49

g/l

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.27

0.20

1.4

1.3

—

(3012544) pH of Venous blood

1.14

0.18

1.6

6.3

—

(4035726) Immunohistochemistry procedure

0.75

0.17

1.8

1.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

178

1.16

0.17

3.2

4.4

18.59

21.45

—

(3021589) Normoblasts [#/volume] in Blood

294

0.88

0.16

10.1

10.8

0.00

e9/l

0.50

240

(3019150) Specific gravity of Urine by Refractometry

140

1.18

0.16

4.1

4.3

—

1.02

—

(3009261) Glucose [Presence] in Urine by Test strip

326

1.13

0.16

3.8

3.9

0.00

estimate

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.17

0.16

1.2

1.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

112

1.19

0.15

3.9

2.5

9.18

0.71

e6/l

—

(3009542) Hematocrit [Volume Fraction] of Blood

745

1.21

0.14

24.5

22.0

40.80

40.54

0.19

705

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

671

1.16

0.14

4.5

5.2

2.86

2.74

mmol/l

0.44

614

(3018095) Leukocytes [#/volume] in Urine

239

0.89

0.12

5.4

3.9

99.76

42.96

e6/l

0.44

171

(3035350) Ketones [Presence] in Urine by Test strip

321

1.10

0.11

3.9

0.00

estimate

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

135

1.14

0.10

3.1

2.8

0.54

0.77

ug/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

106

1.15

0.10

4.3

2.7

4.54

3.14

e6/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.04

0.09

1.0

2.1

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.04

0.09

2.0

1.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

655

1.11

0.09

5.2

4.7

5.97

5.96

mmol/l

0.03

603

(3041096) Erythrocytes [Presence] in Urine by Automated

185

0.90

0.09

3.1

3.5

—

(40761535) Cells panel - Urine sediment

1.10

0.09

3.8

3.5

—

(21494755) Public health laboratory ask at order entry panel

0.79

0.08

1.4

—

(3005719) IgG [Mass/volume] in Serum or Plasma

0.79

0.08

5.8

2.1

8.78

10.21

g/l

—

(36304419) Bacteria [Presence] in Urine

186

1.10

0.08

4.2

3.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.07

0.08

1.3

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.07

0.08

3.4

3.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

112

0.88

0.07

1.4

1.8

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.86

0.07

1.5

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

111

0.89

0.06

3.6

4.2

0.85

0.82

mmol/l

—

104

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

278

1.07

0.05

3.6

4.0

18.57

44.63

ng/l

1.20

192

(3023368) Bacteria identified in Blood by Culture

170

1.07

0.04

3.6

5.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

623

0.98

0.00

15.3

14.0

82.27

80.46

ml/min/173m2

0.31

505

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

473

0.99

0.00

3.4

3.1

49.28

44.70

u/l

0.23

447

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

433

0.99

0.00

2.7

3.0

—

(3030467) Casts [#/volume] in Urine by Automated count

195

1.03

0.00

4.3

3.2

0.41

0.21

e6/l

0.33

149

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

644

0.97

0.00

3.8

4.2

1.30

1.29

mmol/l

0.07

586

(3022948) Iron [Moles/volume] in Serum or Plasma

106

1.04

0.00

3.0

2.3

12.23

12.51

umol/l

0.06

(3002582) Erythrocytes [#/volume] in Urine

214

0.98

0.00

4.3

3.3

758.49

328.68

e6/l

0.23

166

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.92

0.00

1.7

1.4

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.0

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

2.2

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.2

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

116.83

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

5.2

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.2

—

3.82

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.00

-0.00

1.4

1.6

0.83

1.22

g/l

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

21.43

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.7

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.2

—

115.32

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.92

-0.00

1.0

2.2

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

7.24

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.8

—

32.75

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

14.5

—

986.33

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

1.2

—

2032.50

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

-0.00

0.0

1.4

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

41.80

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

16.5

—

1699.00

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.97

-0.00

1.0

1.7

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

36.40

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

1.99

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

9.8

—

9.95

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.7

—

(3000494) Fungus identified in Specimen by Culture

0.89

-0.00

1.3

1.8

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

1.3

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.7

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3019060) Gas panel - Arterial blood

1.02

-0.00

2.4

13.5

—

(3005033) Fetal Nuchal fold Thickness US

0.00

-0.00

0.0

1.4

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

14.40

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.96

-0.00

1.6

—

(3006245) CD3-CD19+ cells/100 cells in Blood

0.00

-0.00

0.0

2.8

—

7.67

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

2.3

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.4

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.0

—

6.19

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

2.26

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

7.44

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.1

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

3.6

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

-0.00

0.0

3.0

—

28.20

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

-0.00

0.0

1.4

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

1.7

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

3.39

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RIBS_STERNUM_CLAVICLE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RIBS_STERNUM_CLAVICLE.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RIBS_STERNUM_CLAVICLE – Benign neoplasm: Ribs, sternum and clavicle

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Ribs, sternum and clavicle

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints