Benign neoplasm: Ribs, sternum and clavicle

CD2_BENIGN_RIBS_STERNUM_CLAVICLE

bone neoplasm: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D16.7& Hospital discharge: ICD-9 — 2133 Hospital discharge: ICD-8 — 21302 Cause of death: ICD-10 — D16.7& Cause of death: ICD-9 — 2133 Cause of death: ICD-8 — 21302 2 out of 7 registries used, show all original rules.	82
4. Check minimum number of events None	82
5. Include endpoints None	82
6. Filter based on genotype QC (FinnGen only)	82

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D16
Name in latin: Neoplasma benignum costae, sterni sive claviculae

NAME	CD2_BENIGN_RIBS_STERNUM_CLAVICLE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D167
HD_ICD_9	2133
HD_ICD_8	21302
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D167
COD_ICD_9	2133
COD_ICD_8	21302
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Ribs, sternum and clavicle based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Ribs, sternum and clavicle

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	837	393	438
Only index persons	695	347	348
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	34.51	37.27	32.09
Only index persons	30.43	34.20	26.66

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	82	42	40
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	41.50	45.12	37.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
79: Matched controls
790

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D16.7

ICD-10 Finland

Benign neoplasm: Ribs, sternum and clavicle

+∞

51.9

21302

ICD-8 Finland

Benign neoplasm of bone and cartilage, Costae, sterni, claviculae

+∞

26.5

2133A

ICD-9 Finland

Benign neoplasm of bone and articular cartilage, Ribs, sternum and clavicle

+∞

11.7

D48.0

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage

44.0

6.9

GAE06

NOMESCO Finland

Excision of lesion of chest wall

75.7

6.5

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

106

2.32

2.54

1.3

22.2

11.8

u/ml

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

113

2.15

2.17

1.4

1.3

9.1

39.3

iu/ml

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

3.96

1.97

1.7

1.3

—

(4010399)

2.49

1.79

1.5

1.3

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

3.51

1.78

1.7

1.3

—

1.5

—

(3042936) Bacteria identified in Isolate by Culture

2.04

1.67

1.1

2.7

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

3.48

1.54

1.8

1.3

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

392

1.71

1.51

8.4

10.6

3.5

4.1

e9/l

1.55

348

(3026493) Urate [Moles/volume] in Serum or Plasma

180

1.75

1.46

1.8

3.0

294.8

5369.1

umol/l

1.07

154

(3026008) Bacteria identified in Urine by Culture

191

1.71

1.39

2.5

3.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

116

1.83

1.36

1.2

1.5

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

150

1.74

1.33

1.2

0.9

0.7

u/ml

—

(3032080) INR in Blood by Coagulation assay

258

1.62

1.29

4.5

8.1

1.1

1.2

inr

—

(36660697) Celiac disease serology panel - Serum

2.07

1.24

1.1

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

503

1.62

1.12

4.4

4.3

15.1

14.9

pmol/l

0.34

463

(42870588) Differential panel, method unspecified - Blood

230

1.56

1.08

8.2

6.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

142

1.64

1.06

2.2

3.0

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

1.77

1.06

4.6

4.8

36.2

33.7

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.35

1.05

2.4

2.5

—

(40768443) Skin Pathology biopsy report

2.32

0.95

1.2

1.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

283

1.49

0.94

3.4

5.0

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.00

0.92

1.0

—

(3044640) Blood type and Crossmatch panel - Blood

202

1.50

0.88

2.3

2.8

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.86

0.87

2.4

124.3

133.3

ng/l

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

396

1.44

0.83

3.2

6.3

6.6

mmol/l

0.02

370

(3000991) Gas panel - Venous blood

1.78

0.79

4.1

10.9

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

273

1.42

0.77

3.3

5.0

35.8

36.1

g/l

0.12

258

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

2.15

0.76

1.8

3.8

—

(40768797) Stomach Pathology biopsy report

1.59

0.72

1.6

1.2

—

(3044889) 12 lead EKG panel

457

0.72

0.71

4.9

3.9

—

(3013707) Erythrocyte sedimentation rate by Westergren method

515

1.43

0.71

5.6

4.0

11.3

11.5

mm/h

0.03

469

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

656

1.61

0.71

15.6

14.8

20.2

20.5

mg/l

0.02

503

(3003327) Ova and parasites identified in Stool by Light microscopy

1.91

0.69

1.6

1.4

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.91

0.69

2.2

2.0

—

(3020682) Albumin/Creatinine [Ratio] in Urine

193

1.42

0.69

3.0

3.9

1.5

9.0

mg/mmol

2.17

124

(3019225) pH of Specimen

1.63

0.66

3.8

3.5

—

(1761868) Lipid panel - Serum or Plasma

246

0.70

0.61

2.4

2.9

—

(3012516) Albumin [Mass/volume] in Urine

180

1.39

0.58

2.7

3.2

11.6

63.1

mg/l

2.01

112

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

609

1.43

0.57

5.5

5.1

2.0

1.9

mu/l

0.41

560

(3025941) Bacteria identified in Stool by Culture

1.67

0.57

1.7

1.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

100

1.48

0.56

1.9

2.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

423

1.32

0.56

5.5

4.4

—

100.0

—

(40768804) Tissue Pathology biopsy report

257

1.33

0.55

2.1

2.0

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.47

0.52

2.5

2.3

2.8

2.4

g/l

2.20

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

232

1.31

0.49

4.1

3.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

430

1.28

0.46

5.0

4.1

—

(3020891) Body temperature

1.65

0.44

2.2

4.2

—

(3003694) ABO and Rh group [Type] in Blood

170

0.72

0.44

1.5

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.45

0.44

1.9

1.8

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.41

0.0

1.5

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.41

0.0

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.39

0.36

12.3

7.9

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

137

1.30

0.35

4.4

3.7

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.39

0.35

5.7

10.0

0.8

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.36

0.34

5.7

9.9

2.2

1.8

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.41

0.32

1.1

2.6

—

(3013512) EKG study

205

1.24

0.32

3.0

4.3

—

(3022145) Colonoscopy Study observation

1.34

0.30

1.5

1.3

—

(3015736) pH of Urine

236

1.21

0.29

3.9

3.8

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

622

0.82

0.29

6.3

5.8

40.1

mmol/mol

0.02

583

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.28

0.27

1.6

1.9

—

(3002256) Pathology report gross observation

1.26

0.26

1.0

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.24

0.26

1.6

2.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

258

1.19

0.26

2.3

2.1

101.8

97.3

pmol/l

0.23

132

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.32

0.25

1.4

1.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

172

1.22

0.25

3.2

4.4

18.6

21.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

240

1.19

0.24

3.9

4.1

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.37

0.24

1.0

5.5

134.4

128.3

g/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

145

1.22

0.23

1.2

1.4

3.1

2.5

g/l

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

644

1.22

0.22

4.0

4.7

4.8

4.6

mmol/l

0.73

592

(40760892) CBC W Ordered Manual Differential panel - Blood

155

1.21

0.22

4.6

5.7

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.20

0.22

1.0

1.3

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

3.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.3

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

3.4

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

3.5

—

59.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.3

—

4.1

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

2.6

—

89.6

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.3

—

106.2

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.3

—

(3021589) Normoblasts [#/volume] in Blood

288

0.86

0.21

10.2

10.9

0.0

e9/l

0.50

236

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.21

0.0

3.5

—

25.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.5

—

65.9

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(40761536) Microorganisms panel - Urine sediment

1.24

0.20

3.2

4.5

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.2

—

(40761511) CBC panel - Blood by Automated count

678

1.22

0.19

16.7

13.2

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

110

1.22

0.18

3.9

2.5

9.2

0.7

e6/l

—

(3012544) pH of Venous blood

1.16

0.18

1.6

6.4

—

(3009542) Hematocrit [Volume Fraction] of Blood

586

1.16

0.18

18.0

16.2

40.9

40.4

0.31

422

(40758558) Short blood count panel - Blood

172

0.84

0.18

5.5

7.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.12

0.16

3.4

3.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.19

0.16

1.2

1.6

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

639

1.17

0.16

4.1

4.7

1.6

1.5

mmol/l

0.98

584

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

639

1.17

0.16

5.2

4.7

6.0

5.9

mmol/l

0.05

589

(36304419) Bacteria [Presence] in Urine

179

1.16

0.16

4.3

3.1

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

131

1.18

0.16

3.1

2.7

0.5

0.8

ug/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.80

0.15

1.3

1.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

0.80

0.15

1.9

6.8

1.1

mmol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

180

0.86

0.15

3.1

3.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

106

0.83

0.14

1.2

1.8

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

104

1.18

0.13

4.3

2.8

4.5

3.1

e6/l

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

655

1.13

0.10

4.5

5.2

2.9

2.7

mmol/l

0.45

600

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.07

0.09

1.0

2.1

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.04

0.09

2.0

1.6

—

(40761535) Cells panel - Urine sediment

1.12

0.09

4.0

3.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.04

0.08

1.0

1.7

—

(4035726)

0.81

0.08

1.8

1.3

—

(3005719) IgG [Mass/volume] in Serum or Plasma

0.79

0.08

5.8

2.1

8.8

10.2

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.11

0.08

1.3

1.6

—

(3019150) Specific gravity of Urine by Refractometry

138

1.11

0.07

4.3

4.4

—

1.0

—

(3009261) Glucose [Presence] in Urine by Test strip

317

1.07

0.06

3.9

0.0

estimate

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

463

0.94

0.06

3.4

3.2

50.3

45.2

u/l

0.26

437

(3018095) Leukocytes [#/volume] in Urine

232

0.93

0.06

5.4

4.0

99.8

43.6

e6/l

0.43

168

(3030467) Casts [#/volume] in Urine by Automated count

189

1.08

0.05

4.3

3.2

0.4

0.2

e6/l

0.34

145

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

421

0.95

0.04

2.7

2.9

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

109

0.91

0.04

3.6

4.2

0.9

0.8

mmol/l

—

101

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

628

0.95

0.02

3.8

4.2

1.3

mmol/l

0.01

573

(3035350) Ketones [Presence] in Urine by Test strip

312

1.04

0.02

4.0

3.9

0.0

estimate

—

(3002582) Erythrocytes [#/volume] in Urine

208

1.01

0.00

4.3

3.4

758.5

330.2

e6/l

0.23

162

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

603

0.98

0.00

15.5

14.1

82.5

80.0

ml/min/173m2

0.47

490

(3023368) Bacteria identified in Blood by Culture

165

1.04

0.00

3.6

5.1

—

(3022948) Iron [Moles/volume] in Serum or Plasma

105

1.05

0.00

3.0

2.3

12.2

12.5

umol/l

0.06

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

276

1.02

0.00

3.7

4.0

18.6

45.1

ng/l

1.21

189

(3028026) IgM [Mass/volume] in Serum or Plasma

1.00

0.00

1.4

1.6

0.8

1.2

g/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.96

0.00

1.0

2.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.95

0.00

1.7

1.4

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.0

—

7.4

—

(3019060) Gas panel - Arterial blood

1.02

0.00

2.4

13.5

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

2.2

—

3.8

—

(3006245) CD3-CD19+ cells/100 cells in Blood

0.00

0.0

2.8

—

7.7

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.2

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

0.0

2.2

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(4198724)

0.00

0.0

1.0

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.7

—

(3012565) Volume of 24 hour Urine

0.00

0.0

1.2

—

2079.0

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.8

—

32.8

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.2

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.4

—

(3011648) Oxygen content in Venous blood

0.00

0.0

11.6

—

9.5

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

3.6

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.0

—

6.2

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

0.0

3.0

—

28.2

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

2.3

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

2.2

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.6

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.8

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

2.3

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

17.2

—

860.8

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.2

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3000494) Fungus identified in Specimen by Culture

0.89

0.00

1.3

1.8

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.0

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.3

—

116.8

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

21.4

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

36.4

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

14.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.4

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3015076) Soybean IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

7.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.3

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

5.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.4

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

3.0

—

2.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.2

—

115.3

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

3.4

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

19.4

—

1599.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.3

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RIBS_STERNUM_CLAVICLE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RIBS_STERNUM_CLAVICLE.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RIBS_STERNUM_CLAVICLE – Benign neoplasm: Ribs, sternum and clavicle

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Ribs, sternum and clavicle

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints