Benign neoplasm of bone and articular cartilage

CD2_BENIGN_BONE_CARTILAGE

chondrosarcoma: A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D16
  • Cause of death: ICD-10 D16

2 out of 7 registries used, show all original rules.

2424

4. Check minimum number of events

None

2424

5. Include endpoints

3415

6. Filter based on genotype QC (FinnGen only)

3415

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasma benignum ossis sive cartilaginis articularis

Similar endpoints

List of similar endpoints to Benign neoplasm of bone and articular cartilage based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 27315 13494 13693
Only index persons 25120 12600 12520
Unadjusted period prevalence (%)
Whole population 0.38 0.39 0.38
Only index persons 0.47 0.46 0.48
Median age at first event (years)
Whole population 31.98 37.34 26.57
Only index persons 30.96 36.54 25.35

-FinnGen-

Key figures

All Female Male
Number of individuals 3415 2042 1373
Unadjusted period prevalence (%) 0.66 0.70 0.61
Median age at first event (years) 40.09 40.27 39.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3060
Matched controls
30599
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
59.4
323.0
390
75
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
+∞
323.0
377
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
10431.2
323.0
792
*
D16.49
ICD-10 Finland
Bones of skull and face
+∞
245.1
232
*
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
+∞
237.6
225
*
9102
FHL
Trepanation or removal of the local bone process
64.5
233.0
271
46
D16.3
ICD-10 Finland
Benign neoplasm: Short bones of lower limb
+∞
200.2
190
*
21306
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis inferioris
+∞
198.1
188
*
2137A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Long bones of lower limb
+∞
165.1
157
*
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
1548.6
150.2
145
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
16.2
119.5
198
130
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
297.6
112.8
114
*
21307
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis inferioris
+∞
93.2
89
*
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
+∞
89.0
85
*
2135A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of upper limb
+∞
86.9
83
*
21303
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis superioris et scapulae
+∞
83.7
80
*
NHR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of ankle or foot
60.1
70.0
82
14
AAP10
NOMESCO Finland
Extirpation of a skull lesion
349.9
68.8
69
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
52.6
64.3
77
15
2138A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of lower limb
+∞
61.7
59
*
D16.6
ICD-10 Finland
Benign neoplasm: Vertebral column
+∞
59.6
57
*
21304
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis superioris
+∞
58.5
56
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
34.0
55.9
73
22
D16.50
ICD-10 Finland
Benign tumor of the mandibular bone or cartilage
+∞
54.3
52
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
6.2
52.4
146
244
D16.51
ICD-10 Finland
Benign tumor of the mandibular bone with urpsrung in teeth
506.1
50.6
50
*
D16.7
ICD-10 Finland
Benign neoplasm: Ribs, sternum and clavicle
+∞
45.9
44
*
21309
ICD-8 Finland
Benign neoplasm of bone and cartilage, Unspecified
+∞
43.8
42
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
24.4
42.4
60
25
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
38.5
41.9
53
14
2130A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bones of skull and face
+∞
37.6
36
*
D16.40
ICD-10 Finland
Orbital bone
+∞
36.5
35
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.1
35.1
114
230
21308
ICD-8 Finland
Benign neoplasm of bone and cartilage, Loco alio sive multiplici
+∞
33.4
32
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
4.9
32.5
109
228
2134A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Scapula and long bones of upper limb
+∞
32.3
31
*
9101
FHL
Bone biopsy
26.2
31.9
44
17
N02AX02
ATC
tramadol; systemic, rectal
1.6
31.7
1170
8503
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.2
31.4
351
1709
NF3AA
NOMESCO Finland
Femur X-ray examination
5.7
30.5
90
163
D16
ICD-10 Finland
Benign neoplasm of bone and articular cartilage
+∞
27.1
26
*
9104
FHL
Autogenous bone graft
38.2
27.1
34
9
M79.6
ICD-10 Finland
Pain in limb
1.6
26.1
974
7011
N03AX16
ATC
pregabalin; oral
1.7
26.0
646
4172
NDK10
NOMESCO Finland
Incision or excision of a bone of hand
22.0
25.6
37
17
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
25.4
1309
10134
N02BE01
ATC
paracetamol; systemic, rectal
1.6
25.4
2460
21942
M25.5
ICD-10 Finland
Pain in joint
1.6
25.3
829
5764
21302
ICD-8 Finland
Benign neoplasm of bone and cartilage, Costae, sterni, claviculae
+∞
25.0
24
*
M01AH05
ATC
etoricoxib; oral
1.5
24.4
1675
13745
NGK05
NOMESCO Finland
Partial or total excision of bone of lower leg
34.8
24.3
31
9
21300
ICD-8 Finland
Benign neoplasm of bone and cartilage, Mandibulae (detibus inclusis)
+∞
24.0
23
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.1
23.6
278
1378
9103
FHL
Partial or complete bone removal
17.2
21.8
34
20
NFK10
NOMESCO Finland
Fenestration or partial or total excision of bone of femur
50.4
21.1
25
5
M85.4
ICD-10 Finland
Solitary bone cyst
34.0
21.1
27
8
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.7
20.3
89
244
ZXA05
NOMESCO Finland
Left side
1.6
20.1
639
4369
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
20.1
490
3124
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
6.2
20.0
54
89
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
11.3
19.9
37
33
2139X
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bone and articular cartilage, site unspecified
+∞
19.8
19
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
4.6
19.3
68
152
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
19.1
2671
24727
EFA10
NOMESCO Finland
Excision of lesion of jaws
34.5
18.9
24
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
18.7
1058
8191
ZZH40
NOMESCO Finland
Substitute of bone
5.7
18.6
53
94
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
18.5
1026
7911
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
17.9
718
5170
AA1AD
NOMESCO Finland
CT of head and brain
1.6
17.4
571
3923
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.1
17.3
99
331
ZXA00
NOMESCO Finland
Right side
1.5
17.3
668
4758
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
12.0
17.3
31
26
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
17.3
227
1175
21305
ICD-8 Finland
Benign neoplasm of bone and cartilage, Pelvis, sacri, coccygis
+∞
16.7
16
*
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
170.9
16.5
17
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
16.5
964
7467
N06AX21
ATC
duloxetine; oral
1.8
16.4
303
1769
S18
ICPC
Laceration/cut
1.4
16.1
1048
8269
Q78.6
ICD-10 Finland
Multiple congenital exostoses
47.7
16.0
19
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
15.9
582
4092
J01DB01
ATC
cefalexin; oral
1.4
15.8
2353
21387
M54.5
ICD-10 Finland
Low back pain
1.4
15.8
879
6738
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.4
15.7
134
572
WX320
NOMESCO Finland
Spinalanesthesy
1.5
15.7
565
3952
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
4.9
15.7
51
106
2131A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Lower jaw bone
+∞
15.6
15
*
Q78.48
ICD-10 Finland
Enchondromatosis
+∞
15.6
15
*
R01AD09
ATC
mometasone; nasal
1.4
15.5
1233
10060
NF1AA
NOMESCO Finland
Hip X-ray examination
2.0
15.5
203
1050
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.9
15.4
241
1332
J01DA01
ATC
[U] cefalexin; systemic
1.4
15.4
1728
14916
EDA10
NOMESCO Finland
Biopsy of mandible
13.1
15.2
26
20
M03BX02
ATC
tizanidine; oral
1.4
15.0
1740
15071
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
10.9
15.0
28
26
SPAT1153
SPAT
Removal of sutures
1.4
14.9
787
5959
N03AX12
ATC
gabapentin; oral
1.6
14.9
393
2548
M01AE02
ATC
naproxen; oral, rectal
1.4
14.9
1568
13364
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.8
14.8
62
165
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
31.8
14.8
19
6
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
5.4
14.6
43
80
2136A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Pelvic bones, sacrum and coccyx
+∞
14.6
14
*
D16.41
ICD-10 Finland
Benign tumor of the maxillary bone originating in teeth
+∞
14.6
14
*
D16.5
ICD-10 Finland
Benign neoplasm: Lower jaw bone
+∞
14.6
14
*
A02BC02
ATC
pantoprazole; systemic
1.4
14.5
1703
14738
J01AA02
ATC
doxycycline; systemic
1.4
14.4
2140
19226
NG4AA
NOMESCO Finland
Lower leg X-ray examination
2.8
13.9
91
335
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
13.9
332
2092
X58
ICD-10 Finland
Exposure to other specified factors
1.6
13.9
381
2495
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.7
13.8
59
160
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.7
697
5224
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
13.7
1399
11809
21301
ICD-8 Finland
Benign neoplasm of bone and cartilage, Columnae vertebralis (sacro et coccyge exclusis)
+∞
13.5
13
*
R51.80
ICD-10 Finland
Headache
1.6
13.5
398
2647
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.7
13.4
296
1825
NG1AD
NOMESCO Finland
Knee CT examination
4.3
13.4
49
116
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
10.5
12.7
24
23
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
70.1
12.6
14
*
J01FF01
ATC
clindamycin; systemic
1.4
12.5
687
5210
NK6DT
NOMESCO Finland
Bone biopsy with MRI guidance
+∞
12.5
12
*
M67.4
ICD-10 Finland
Ganglion
1.9
12.4
175
931
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
12.4
852
6722
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
12.4
946
7595
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
12.3
360
2393
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.7
12.2
290
1824
P01AB01
ATC
metronidazole; oral, rectal
1.3
12.2
1034
8433
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
12.1
163
853
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
2.8
12.0
77
282
M01AB05
ATC
diclofenac; systemic, rectal
1.3
12.0
1810
16036
NFK99
NOMESCO Finland
Other operation on bone of femur
21.4
12.0
17
8
UKC02
NOMESCO Finland
Cystoscopy
1.6
11.8
331
2173
WX204
NOMESCO Finland
Axillary plexus blockaced
2.5
11.8
93
383
J01FA09
ATC
clarithromycin; systemic
1.4
11.8
835
6609
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
11.8
215
1250
A02BC05
ATC
esomeprazole; systemic
1.3
11.8
1029
8418
R01AD12
ATC
fluticasone furoate; nasal
1.4
11.8
800
6290
R52.9
ICD-10 Finland
Pain, unspecified
1.8
11.6
203
1165
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
11.5
204
1177
2133A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Ribs, sternum and clavicle
+∞
11.5
11
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
11.5
11
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
11.4
249
1531
9109
FHL
Other measure in this category
15.1
11.3
18
12
SPAT1263
SPAT
Sampling
1.3
11.3
1095
9082
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
11.3
685
5278
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
11.0
616
4677
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.5
11.0
87
359
L03
ICPC
Low back symptom/complaint
1.4
10.9
595
4501
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
10.8
1313
11222
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
8.9
10.7
22
25
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.6
10.6
251
1577
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
10.6
1450
12574
L08
ICPC
Shoulder symptom/complaint
1.5
10.6
437
3127
WX110
NOMESCO Finland
Local anesthesy
1.3
10.5
1922
17313
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
10.5
578
4368
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
10.5
248
1556
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
10.5
477
3482
J01FA10
ATC
azithromycin; systemic
1.3
10.5
1623
14300
75665
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Exostosis cartilaginea multiplex
110.4
10.4
11
*
R01AD08
ATC
fluticasone; nasal
1.4
10.3
740
5845
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
10.3
1498
13080
SPAT1229
SPAT
Assessment of need for aid
1.8
10.3
164
917
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
10.2
423
3028
M85.6
ICD-10 Finland
Other cyst of bone
23.4
10.2
14
6
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
10.2
219
1342
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
10.2
522
3899
M01AX17
ATC
nimesulide; oral
1.4
10.2
560
4236
R03AC02
ATC
salbutamol; inhalant
1.3
10.1
1380
11943
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.0
1975
17915
ZZH20
NOMESCO Finland
Graft of patients own bone
6.1
10.0
26
43
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
40.2
10.0
12
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
9.9
569
4329
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
9.8
1038
8666
J01FA06
ATC
roxithromycin; oral
1.3
9.8
1017
8474
A02BC01
ATC
omeprazole; systemic
1.4
9.7
633
4920
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
1.8
9.7
153
849
M02AA07
ATC
piroxicam; topical
1.3
9.7
857
6981
L15
ICPC
Knee symptom/complaint
1.4
9.5
478
3550
A02BC03
ATC
lansoprazole; oral
1.3
9.5
690
5453
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.5
525
3967
J01CA04
ATC
amoxicillin; systemic
1.3
9.4
2290
21251
S62.6
ICD-10 Finland
Fracture of other finger
2.0
9.4
117
596
NHR99
NOMESCO Finland
Other operation for tumour of ankle or foot
30.1
9.4
12
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.4
412
2982
L13
ICPC
Hip symptom/complaint
1.5
9.4
331
2295
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
9.2
142
786
UJF32
NOMESCO Finland
Coloscopy
1.4
9.1
578
4471
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
6.3
9.1
23
37
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.0
1057
8925
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
2.5
9.0
70
289
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
3.2
9.0
44
137
M89.3
ICD-10 Finland
Hypertrophy of bone
18.6
8.9
13
7
M12.2
ICD-10 Finland
Villonodular synovitis (pigmented)
18.6
8.9
13
7
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
8.9
1561
13848
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.8
8.9
137
759
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.8
696
5564
B01AB05
ATC
enoxaparin; parenteral
1.3
8.7
678
5407
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.6
8.7
220
1409
R93.7
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
14.1
8.7
14
10
N02AA05
ATC
oxycodone; systemic
1.5
8.7
277
1876
M01AC06
ATC
meloxicam; systemic, rectal
1.3
8.7
886
7340
H02AB06
ATC
prednisolone; systemic
1.3
8.6
1143
9785
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
8.6
247
1628
M85.0
ICD-10 Finland
Fibrous dysplasia (monostotic)
16.3
8.5
13
8
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.1
8.5
92
443
E0000UV
ATC
NA
1.3
8.5
996
8397
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
8.5
610
4802
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.4
393
2882
D16.9
ICD-10 Finland
Benign neoplasm: Bone and articular cartilage, unspecified
+∞
8.3
8
*
D16.4
ICD-10 Finland
Benign neoplasm: Bones of skull and face
+∞
8.3
8
*
XKD00
NOMESCO Finland
Uroflowmetry
1.5
8.3
293
2031
ND2CG
NOMESCO Finland
Extensive MRI of hand
8.5
8.3
17
20
R53
ICD-10 Finland
Malaise and fatigue
1.4
8.2
465
3525
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
8.2
1188
10268
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
14.5
8.2
13
9
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
7.5
8.1
18
24
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.6
8.1
217
1412
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
33.4
8.1
10
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
11.7
8.1
14
12
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
1.8
8.0
139
800
TAKUU
NOMESCO Finland
NA
3.8
8.0
32
85
NHR30
NOMESCO Finland
Complete excision of soft tissue tumour of ankle or foot
22.1
8.0
11
5
J02AC01
ATC
fluconazole; systemic
1.3
8.0
1025
8722
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
8.0
238
1589
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
7.9
473
3613
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.9
388
2865
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
7.9
243
1636
ZZH31
NOMESCO Finland
Bone allograft, small pieces
4.5
7.9
26
58
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
2.5
7.8
58
234
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
7.8
633
5067
M48.0
ICD-10 Finland
Spinal stenosis
1.5
7.8
239
1604
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
7.7
129
732
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
7.7
252
1717
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.6
7.7
219
1441
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
7.7
164
1005
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
2.8
7.7
47
171
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
7.7
754
6196
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.6
1553
13916
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.6
7.5
172
1075
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.5
663
5369
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.5
319
2293
ND3CG
NOMESCO Finland
Extensive MRI of fingers
10.0
7.5
14
14
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
7.5
259
1784
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
2.7
7.5
49
186
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.7
7.4
141
836
NGR99
NOMESCO Finland
Other operation for tumour of knee or lower leg
80.3
7.4
8
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
80.3
7.4
8
*
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
80.3
7.4
8
*
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.7
7.4
142
842
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
1.7
7.3
152
926
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.3
983
8391
D16.91
ICD-10 Finland
Benign tumor in unspecified localization in bone with urpsrung in teeth
+∞
7.3
7
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.2
7.3
72
337
9166
FHL
Bone graft to promote ossification
9.4
7.3
14
15
R06AE07
ATC
cetirizine; oral
1.2
7.3
1138
9884
Q78.1
ICD-10 Finland
Polyostotic fibrous dysplasia
30.1
7.1
9
*
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
20.1
7.1
10
5
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
7.0
239
1641
A02BA02
ATC
ranitidine; systemic
1.4
7.0
425
3256
L17
ICPC
Foot/toe symptom/complaint
1.3
7.0
562
4492
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
6.9
295
2120
WX002
NOMESCO Finland
Sedation and analgesia
1.4
6.9
434
3337
L16
ICPC
Ankle symptom/complaint
1.5
6.9
235
1616
R06.0
ICD-10 Finland
Dyspnoea
1.3
6.9
531
4213
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
6.9
246
1706
L12
ICPC
Hand/finger symptom/complaint
1.4
6.9
325
2385
J20
ICD-10 Finland
Acute bronchitis
1.5
6.9
214
1446
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.6
6.8
163
1028
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.1
6.8
71
341
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
3.0
6.8
36
121
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
40.1
6.8
8
*
9105
FHL
Homogeneous or heterogeneous bone graft, e.g., joint graft
40.1
6.8
8
*
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.7
978
8405
EBB10
NOMESCO Finland
Insertion of dental implant
3.0
6.7
36
122
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
6.6
186
1225
M85.8
ICD-10 Finland
Other specified disorders of bone density and structure
5.5
6.6
18
33
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
12.3
6.6
11
9
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.7
6.5
124
737
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.5
651
5345
NE1CM
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with 3 Tesla magnet
10.0
6.5
12
12
WZA90
NOMESCO Finland
Other doctors statement
1.3
6.5
567
4576
H02AB04
ATC
methylprednisolone; systemic
1.4
6.5
329
2441
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.5
665
5479
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.9
6.5
94
514
-
ICD-10 Finland
NA
2.3
6.4
55
240
M79.1
ICD-10 Finland
Myalgia
1.4
6.4
300
2196
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.4
898
7679
R50.9
ICD-10 Finland
Fever, unspecified
1.4
6.4
312
2304
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
6.4
174
1136
SPAT1312
SPAT
General health counselling
1.3
6.4
792
6679
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.2
6.4
60
274
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.8
6.4
110
635
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
3.9
6.4
24
62
N06AA09
ATC
amitriptyline; systemic
1.5
6.3
219
1514
M01AH03
ATC
valdecoxib; oral
1.6
6.3
145
910
EDB00
NOMESCO Finland
Partial excision of mandible
11.0
6.3
11
10
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
2.0
6.3
78
402
ND1CM
NOMESCO Finland
Wrist and hand extensive MRI examination with 3 Tesla magnet
9.3
6.3
12
13
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
18.0
6.3
9
5
EEB00
NOMESCO Finland
Partial excision of maxilla
18.0
6.3
9
5
D07AC01
ATC
betamethasone; topical
1.2
6.3
797
6736
WX203
NOMESCO Finland
Infraclavicular plexus blockade
2.2
6.3
59
270
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
6.2
6
*
4339
FHL
Other measure in this category
+∞
6.2
6
*
2132A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Vertebral column, excluding sacrum and coccyx
+∞
6.2
6
*
4332
FHL
Lower jaw resection or tumor removal
+∞
6.2
6
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
6.2
720
6017
1220
FHL
Arthroscopy
1.8
6.2
92
505
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
26.7
6.2
8
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
26.7
6.2
8
*
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.2
1186
10475
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.6
6.1
151
964
J02AC02
ATC
itraconazole; systemic
1.3
6.1
406
3154
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
6.1
327
2453
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.1
345
2612
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.6
6.0
147
937
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.3
6.0
530
4280
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
6.7
6.0
14
21

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1438
11171
1.50
27.75
2.1
2.0
—
—
—
0
0
2365
20461
1.51
25.70
4.5
4.0
10.2
11.0
mm/h
2.69
2203
19068
2353
20879
1.41
18.20
7.6
7.3
77.2
76.7
u/l
0.19
2226
19743
662
4774
1.48
16.86
1.3
1.3
9.0
10.0
u/ml
0.18
270
1944
1532
12834
1.35
16.08
4.0
3.9
—
—
—
0
0
1807
15521
1.35
16.07
4.5
4.7
6.5
6.6
mmol/l
2.12
1696
14435
2034
17792
1.35
16.02
4.6
4.2
2899.6
1680.0
e6/l
0.18
17
237
559
3975
1.49
15.12
1.4
1.4
522.7
515.8
titre
0.03
105
798
679
5048
1.43
14.49
1.4
1.3
27.2
30.3
iu/ml
0.17
210
1571
1062
8520
1.36
14.35
2.3
2.3
—
—
—
0
0
2116
18832
1.32
13.63
4.5
4.1
—
—
—
0
0
1336
11166
1.32
13.45
4.6
4.8
36.1
36.0
g/l
0.30
1223
10433
3005
28327
1.51
13.30
14.2
12.8
21.5
22.5
mg/l
0.95
2443
22108
888
7007
1.36
13.12
2.5
2.5
1641.9
4458.3
umol/l
2.42
778
6166
827
6489
1.36
12.59
2.3
2.2
—
—
—
0
0
1122
9232
1.32
12.34
5.6
6.0
—
—
—
0
0
1489
12733
1.30
12.34
6.5
6.6
1.2
1.2
mmol/l
0.03
1239
10778
3010
28471
1.48
12.19
15.4
14.2
139.7
139.7
mmol/l
1.20
2934
27776
1358
11510
1.30
11.90
5.8
6.0
1.2
1.2
mmol/l
0.06
1215
10485
1204
10045
1.31
11.86
6.9
8.3
1.2
1.2
inr
0.55
318
3019
478
3447
1.45
11.84
1.3
1.3
—
—
—
0
0
3014
28561
1.47
11.63
15.6
14.3
4.0
4.0
mmol/l
0.31
2929
27817
1562
13599
1.27
10.69
3.7
3.5
0.0
0.0
estimate
1.57
304
2473
1578
13776
1.27
10.48
5.9
6.1
11.3
11.1
umol/l
0.15
1484
13087
941
7695
1.31
10.47
2.1
2.1
214.2
226.7
u/l
0.11
898
7259
2385
21905
1.29
10.44
4.2
4.0
14.7
14.6
pmol/l
0.08
2207
20160
1542
13442
1.27
10.31
3.7
3.4
0.0
0.0
estimate
0.50
307
2496
1011
8367
1.30
10.24
2.7
2.5
60.6
57.2
u/l
0.31
920
7757
1543
13468
1.27
10.14
4.9
4.7
0.0
0.0
estimate
0.50
314
2564
3096
29700
1.45
9.11
13.6
11.8
—
—
—
0
0
182
1133
1.64
8.84
1.3
1.3
0.6
0.9
u/ml
0.31
12
98
1633
14492
1.24
8.81
6.1
6.1
0.2
0.2
e9/l
0.09
1453
12832
1123
9586
1.26
8.50
3.3
3.3
32.1
48.3
ng/l
1.11
701
5936
869
7203
1.28
8.40
4.3
3.8
0.0
0.0
estimate
1.28
301
2488
490
3761
1.35
8.28
1.3
1.2
—
—
—
0
0
2740
25881
1.30
8.17
5.0
4.7
2.7
2.0
mu/l
0.32
2548
24023
1568
13947
1.23
7.98
6.0
5.9
0.6
0.6
e9/l
0.22
1375
12153
1572
13991
1.23
7.94
6.0
5.9
0.0
0.0
e9/l
0.08
1375
12181
483
3723
1.35
7.92
2.1
2.0
—
—
—
0
0
1613
14408
1.23
7.83
6.0
5.9
2.0
2.0
e9/l
0.12
1439
12799
863
7204
1.26
7.78
3.8
3.5
—
—
—
0
0
1290
11269
1.23
7.72
2.4
2.2
77.5
75.7
nmol/l
1.25
1177
10302
1026
8745
1.25
7.70
3.0
3.3
2.4
2.4
mmol/l
0.24
900
7764
85
446
1.93
7.44
1.5
1.6
—
—
—
0
0
790
6563
1.27
7.36
1.3
1.3
1.2
1.6
u/ml
0.53
215
1789
415
3160
1.36
7.36
1.7
1.7
—
—
—
0
0
1775
16096
1.21
7.14
8.4
9.0
4.0
4.0
e9/l
0.10
1565
14139
177
1157
1.56
7.07
1.1
1.1
—
—
—
0
0
814
6815
1.26
7.06
3.6
3.9
92.4
92.4
%
0.02
792
6638
170
1122
1.54
6.53
1.3
1.2
—
—
—
0
0
289
2128
1.39
6.31
2.6
2.7
9.7
10.4
g/l
2.83
261
1956
1415
12658
1.20
6.27
6.2
6.1
0.7
0.7
%
0.08
1310
11863
104
614
1.72
6.27
1.5
1.7
14189.9
12687.4
e6/l
0.13
80
454
880
7517
1.23
6.25
3.3
3.1
—
—
—
0
0
1463
13136
1.20
6.20
6.5
6.3
8.5
8.5
%
0.06
1365
12364
1454
13049
1.20
6.19
6.2
6.1
2.9
2.8
%
0.31
1353
12203
422
3310
1.31
6.09
5.2
6.1
1.0
1.0
mmol/l
0.24
402
3090
61
307
2.00
6.08
1.5
1.7
59.4
58.1
%
0.08
37
194
877
7534
1.22
5.83
3.0
2.9
—
—
—
0
0
1484
13393
1.19
5.82
6.1
5.9
56.4
56.8
%
0.62
1388
12596
262
1936
1.38
5.62
2.6
2.6
67.2
66.7
g/l
0.53
240
1779
1497
13564
1.18
5.51
6.3
6.1
29.0
28.6
%
0.75
1398
12714
2802
26851
1.24
5.49
4.5
4.2
5.8
5.9
mmol/l
0.70
2581
24780
1158
10285
1.19
5.31
1.9
1.9
100.6
96.5
pmol/l
1.82
613
5429
279
2102
1.36
5.31
3.8
3.3
—
—
—
0
0
760
6499
1.22
5.22
2.7
2.9
1011.0
1175.9
ng/l
0.63
634
5464
1392
12588
1.18
5.12
3.0
2.8
105.0
113.8
ug/l
1.08
1307
11756
678
5749
1.22
5.05
1.6
1.5
2.2
2.3
g/l
1.83
432
3624
451
3666
1.27
4.92
2.5
2.4
111.8
125.0
ug/g
0.53
349
2940
3250
31833
1.43
4.86
21.0
18.6
90.6
90.6
fl
0.29
3214
31454
3250
31834
1.43
4.84
21.0
18.6
30.2
30.2
pg
0.25
3214
31452
3250
31837
1.43
4.81
21.1
18.7
4.5
4.5
e12/l
0.04
3178
31048
3251
31849
1.43
4.81
21.2
18.8
136.3
136.4
g/l
0.12
3214
31461
81
483
1.69
4.79
2.5
3.6
355.7
881.1
u/ml
0.46
72
456
318
2481
1.31
4.78
3.5
3.9
—
—
—
0
0
644
5468
1.22
4.71
2.4
2.5
6.1
6.2
e6/l
0.07
560
4803
3250
31846
1.43
4.71
21.1
18.7
6.7
6.7
e9/l
0.09
3179
31059
865
7554
1.19
4.70
4.0
3.9
7.4
7.4
ph
0.72
179
1469
758
6554
1.20
4.58
4.8
4.4
—
—
—
0
0
3246
31813
1.41
4.56
21.2
18.7
256.3
255.3
e9/l
0.42
3182
31094
502
4170
1.24
4.53
3.5
3.6
0.8
0.8
mmol/l
0.68
473
3925
2085
19599
1.16
4.41
3.4
3.0
45.0
45.2
u/l
0.06
1944
18502
221
1659
1.36
4.35
2.0
1.8
1.4
1.4
g/l
0.04
200
1537
574
4860
1.22
4.30
3.3
3.5
598.1
472.9
ng/l
0.21
386
3472
53
289
1.85
4.28
2.7
3.1
2.2
24.4
nmol/l
0.61
47
281
813
7113
1.19
4.28
3.0
3.0
—
—
—
0
0
332
2650
1.28
4.22
2.4
2.1
344.3
370.4
nmol/l
1.75
309
2433
2628
25213
1.18
4.11
5.6
5.2
38.8
39.2
mmol/mol
1.35
2449
23592
297
2348
1.29
4.07
1.2
1.2
—
—
—
0
0
589
5054
1.20
3.83
2.8
2.7
561.9
549.9
mosm/kgh2o
0.60
494
4307
237
1834
1.31
3.83
2.8
3.3
4.5
4.5
pmol/l
0.13
213
1650
45
243
1.86
3.79
1.4
1.5
38.5
33.6
%
0.38
31
148
815
7200
1.17
3.77
3.0
3.0
0.4
0.4
e6/l
0.11
631
5385
533
4537
1.21
3.77
2.7
2.9
2.4
2.4
mmol/l
0.65
464
3977
214
1640
1.33
3.71
1.5
1.3
25.3
27.3
iu/l
0.39
189
1402
110
758
1.47
3.59
1.3
1.2
8.2
8.1
u/ml
0.00
14
124
249
1959
1.29
3.57
1.3
1.3
248.9
211.4
u/ml
0.21
236
1817
111
767
1.46
3.57
1.4
1.4
248.7
294.5
ug/g
1.34
55
427
65
399
1.64
3.54
1.8
1.3
5.4
3.9
ug/l
0.32
56
362
390
3239
1.23
3.53
1.4
1.5
—
—
—
0
0
240
1883
1.30
3.52
1.4
1.4
—
—
—
0
0
623
5414
1.18
3.50
1.6
1.6
442.8
36114565.0
pmol/l
5.04
514
4591
754
6657
1.17
3.49
4.2
4.3
—
—
—
0
0
835
7438
1.16
3.45
4.8
4.4
1.9
2.3
ug/l
1.57
773
6725
207
1597
1.32
3.44
2.2
2.3
—
—
—
0
0
55
327
1.69
3.39
1.2
1.3
—
—
nmol/l
—
0
0
249
1974
1.28
3.38
2.9
2.8
3.9
4.1
e9/l
0.80
191
1601
709
6248
1.17
3.35
1.8
1.7
1.0
1.1
mg/l
0.12
545
4686
107
746
1.45
3.31
1.3
1.2
36.2
3.1
u/ml
—
9
79
303
2466
1.25
3.31
2.5
2.3
0.2
0.2
g/l
1.18
287
2308
61
376
1.63
3.29
1.2
1.3
0.2
0.3
nmol/l
—
5
22
2906
28255
1.19
3.28
4.7
4.5
2.8
2.8
mmol/l
0.84
2694
26386
26
122
2.14
3.25
1.5
1.8
2.0
2.0
umol/l
0.06
26
116
744
6599
1.16
3.23
2.3
2.1
2.8
2.9
mg/l
0.23
645
5666
160
1202
1.35
3.21
1.6
1.6
314.9
299.2
mu/l
0.19
149
1085
669
5888
1.17
3.21
4.2
3.8
1.0
1.0
kg/l
0.25
100
829
646
5672
1.17
3.19
1.5
1.5
21.0
20.5
nmol/l
0.36
556
4912
896
8076
1.15
3.11
3.4
3.3
8.0
7.8
mmol/l
0.33
760
6885
874
7868
1.15
3.09
3.1
3.1
55.3
96.8
e6/l
0.85
673
6006
234
1864
1.27
3.08
1.3
1.3
28.3
48.9
au/ml
—
6
79
38
209
1.83
3.08
2.1
2.1
14.8
13.1
%
0.32
20
96
1998
18964
1.13
3.05
3.8
3.5
—
—
—
0
0
18
74
2.44
3.04
3.3
2.9
—
—
—
0
0
2866
27874
1.18
3.02
4.4
4.1
4.7
4.7
mmol/l
1.34
2662
26200
700
6213
1.16
3.00
3.9
3.4
—
—
—
0
0
80
538
1.50
3.00
1.1
1.1
—
—
—
0
0
353
2954
1.22
2.99
24.0
21.8
1.2
1.3
inr
0.43
51
438
295
2425
1.24
2.97
3.7
4.1
35.2
20.8
ug/l
0.35
232
1938
56
348
1.62
2.96
1.2
1.3
—
—
—
0
0
249
2013
1.26
2.91
2.2
2.4
6.4
7.4
ug/l
0.39
216
1803
278
2280
1.24
2.87
4.4
4.2
1.0
0.9
%
0.24
73
618
63
407
1.56
2.85
1.4
1.5
—
—
—
0
0
254
2064
1.25
2.85
4.0
3.7
1.2
1.2
mmol/l
0.48
218
1804
230
1848
1.26
2.84
3.2
3.9
72.7
82.9
ng/l
1.42
206
1632
2755
26743
1.16
2.84
3.9
3.7
1.3
1.3
mmol/l
1.77
2550
24888
35
193
1.82
2.84
1.5
2.0
3.2
4.0
mg/l
0.96
35
184
370
3130
1.20
2.81
2.6
2.8
9.5
7.5
umol/l
0.66
318
2722
167
1291
1.31
2.79
2.4
2.3
—
—
—
0
0
251
2043
1.25
2.78
4.5
4.3
0.1
0.4
%
0.74
61
474
79
540
1.47
2.76
1.1
1.1
—
—
—
0
0
255
2081
1.24
2.76
4.3
4.0
0.5
0.6
%
0.18
60
446
43
255
1.70
2.74
1.3
1.4
116401.5
86941.6
e6/l
0.14
25
178
2845
27701
1.16
2.73
4.3
4.1
1.5
1.5
mmol/l
0.18
2639
25904
3076
30147
1.20
2.71
10.9
9.7
27.4
26.9
u/l
0.67
2982
29247
499
4348
1.17
2.71
1.8
1.7
1202.5
1172.3
nmol/l
0.31
381
3349
256
2096
1.24
2.70
2.1
2.3
12.7
12.9
nmol/l
0.17
232
1877
45
272
1.66
2.68
2.2
2.5
1.2
1.2
e9/l
0.08
26
156
107
779
1.39
2.67
1.2
1.3
109.0
87.1
titre
—
10
69
81
562
1.45
2.64
4.0
3.7
—
—
—
0
0
262
2156
1.23
2.64
1.2
1.2
144.4
155.9
iu/ml
0.16
96
810
1021
9369
1.13
2.64
3.6
3.6
58.4
90.9
e6/l
1.12
728
6512
84
589
1.44
2.60
4.5
4.3
2.1
2.5
mmol/l
0.81
56
387
355
3019
1.20
2.57
1.4
1.3
—
—
—
0
0
80
558
1.44
2.55
6.0
8.2
10.9
11.4
mmol/l
0.75
70
499
53
339
1.57
2.54
1.4
1.3
—
—
—
0
0
80
559
1.44
2.53
6.0
8.2
104.7
105.3
mmol/l
0.67
70
500
448
3894
1.17
2.52
1.9
2.2
29.6
29.7
s
0.05
429
3770
262
2170
1.22
2.49
4.5
4.3
0.2
0.1
%
0.54
67
566
418
3616
1.18
2.49
1.7
1.6
—
—
—
0
0
169
1334
1.28
2.45
8.6
11.6
—
—
—
0
0
496
4359
1.16
2.42
2.7
2.6
1.3
1.1
e6/l
0.15
283
2432
246
2032
1.23
2.41
2.4
2.4
17.3
22.4
au/ml
0.49
14
134
458
4003
1.17
2.40
2.2
2.4
14.6
13.7
umol/l
1.69
426
3725
283
2372
1.21
2.40
4.1
3.8
—
—
—
0
0
5
8
6.26
2.37
1.0
1.0
—
—
—
0
0
33
191
1.73
2.33
1.0
1.0
—
—
—
0
0
106
790
1.35
2.33
5.6
6.9
1.3
1.3
mmol/l
0.10
90
685
61
414
1.48
2.27
1.5
1.8
—
—
—
0
0
831
7596
1.12
2.25
3.9
4.0
5.6
8.8
mg/mmol
2.05
528
4854
77
548
1.41
2.24
2.2
2.3
130.6
130.5
g/l
0.00
56
399
421
3678
1.16
2.23
2.3
2.4
2.4
2.4
g/l
1.22
395
3429
1322
12403
1.11
2.22
9.6
9.0
0.0
0.0
e9/l
1.28
1086
10139
76
541
1.41
2.21
1.5
1.7
—
—
—
0
0
47
304
1.55
2.19
2.1
1.4
0.3
0.4
g/l
1.42
25
211
47
304
1.55
2.19
2.1
1.4
2.7
2.9
g/l
0.52
24
213
58
393
1.48
2.18
2.2
2.1
5.5
6.0
umol/l
0.19
34
285
120
922
1.31
2.17
1.4
1.4
10.2
9.7
u/l
0.14
102
761
268
2259
1.20
2.17
1.4
1.4
—
—
—
0
0
30
173
1.74
2.16
1.6
1.4
4.9
7.5
u/l
1.53
25
147
47
305
1.55
2.16
2.1
1.4
5.7
6.6
g/l
1.36
25
213
23
123
1.88
2.11
1.2
1.1
—
—
—
0
0
667
6047
1.13
2.07
1.9
1.9
—
—
—
0
0
792
7254
1.12
2.06
3.2
3.3
323.2
362.5
mg/l
0.08
498
4602
389
3404
1.16
2.03
2.4
2.5
25.2
23.5
%
1.22
327
2938
72
517
1.40
2.02
1.5
1.4
0.3
0.4
nmol/l
0.19
58
406
37
232
1.60
1.99
1.3
1.5
1.4
1.2
promille
0.27
27
184
104
795
1.32
1.98
1.1
1.2
—
—
—
0
0
93
700
1.34
1.97
4.4
4.1
7.4
7.4
ph
0.13
80
582
23
128
1.80
1.89
1.3
3.0
213.1
171.1
umol/l
—
9
73
23
128
1.80
1.89
1.1
1.1
397.6
192.8
iu/ml
0.38
23
128
46
308
1.50
1.87
2.2
1.5
—
—
—
0
0
62
441
1.41
1.86
1.0
1.1
2.1
5.4
u/ml
2.29
28
177
455
4054
1.14
1.86
2.8
2.8
3.1
2.7
e6/l
0.40
246
2138
68
493
1.39
1.83
2.4
1.7
1.1
0.8
g/l
0.92
43
380
65
469
1.39
1.81
1.8
1.7
—
—
—
0
0
97
747
1.31
1.78
4.3
3.9
1.4
1.5
mg/l
0.43
91
700
199
1668
1.20
1.76
1.3
1.2
—
—
—
0
0
275
2372
1.17
1.76
1.4
1.5
—
—
—
0
0
20
110
1.82
1.72
1.1
1.2
—
0.3
—
0
10
57
406
1.41
1.72
1.6
1.6
—
—
—
0
0
15
75
2.00
1.69
1.0
1.2
43.6
37.9
g/l
—
5
44
31
195
1.60
1.68
2.4
2.7
463.9
572.1
e6/l
0.59
19
160
327
2870
1.15
1.68
1.4
1.4
—
—
—
0
0
222
1890
1.19
1.67
2.5
2.8
184.4
176.3
ng/l
0.07
199
1704
162
1339
1.22
1.66
2.4
2.2
4533.5
4590.6
u/l
0.01
53
518
108
853
1.27
1.66
1.9
2.4
545.4
436.8
ug/l
0.20
96
798
271
2348
1.17
1.65
8.2
9.0
122.2
123.2
g/l
0.34
262
2260
757
7011
1.10
1.59
6.4
6.7
—
—
—
0
0
15
77
1.95
1.59
1.3
1.5
—
—
—
0
0
6
20
3.00
1.58
1.2
1.2
—
—
—
0
0
28
175
1.60
1.57
1.3
1.2
—
—
—
0
0
58
423
1.38
1.55
1.4
1.2
—
—
—
0
0
45
314
1.44
1.54
2.7
2.9
—
—
—
0
0
178
1498
1.20
1.54
2.5
3.1
28.3
46.0
u/ml
2.16
170
1446
85
659
1.30
1.53
2.0
1.9
193.4
204.8
pmol/l
0.45
80
622
112
900
1.25
1.51
1.7
1.8
39.7
38.9
nmol/l
0.13
107
874
13
65
2.00
1.48
3.7
3.3
191.5
175.2
ng/l
—
7
39
319
2823
1.14
1.48
7.6
8.1
1.1
1.1
mmol/l
0.13
257
2186
107
858
1.26
1.48
2.7
2.5
—
—
—
0
0
19
109
1.75
1.46
1.3
1.3
—
—
—
0
0
10
45
2.23
1.46
1.2
2.1
—
—
—
0
0
114
925
1.24
1.43
1.9
1.7
1.2
1.2
g/l
0.36
104
877
13
66
1.97
1.43
1.1
1.2
—
—
—
0
0
29
188
1.55
1.42
2.6
2.8
0.2
0.2
e9/l
0.03
19
160
29
188
1.55
1.42
1.1
1.1
4.9
10.2
iu/ml
—
8
54
319
2832
1.14
1.42
7.7
8.1
5.1
5.1
kpa
0.15
300
2708
35
237
1.48
1.41
1.2
1.1
—
—
—
0
0
319
2833
1.14
1.41
7.7
8.1
12.7
12.6
kpa
0.13
300
2711
53
388
1.37
1.41
1.1
1.1
1.4
1.5
g/l
0.54
48
354
103
828
1.25
1.41
1.1
1.1
0.8
4.3
u/ml
—
9
117
10
46
2.18
1.40
1.0
1.1
—
—
—
0
0
139
1157
1.21
1.38
1.9
1.5
20.2
15.7
u/ml
—
5
32
32
214
1.50
1.38
1.2
1.2
—
—
—
0
0
189
1618
1.18
1.38
4.7
5.3
—
—
—
0
0
55
408
1.35
1.36
1.6
1.5
—
—
—
0
0
84
663
1.27
1.35
1.1
1.1
0.6
1.4
u/ml
1.30
36
273
21
128
1.64
1.33
1.2
2.0
—
—
—
0
0
35
241
1.46
1.32
3.1
2.1
—
—
—
0
0
6
24
2.50
1.30
1.2
1.3
—
—
—
0
0
27
177
1.53
1.28
4.9
7.0
—
—
—
0
0
33
226
1.46
1.28
1.3
1.3
0.2
0.5
u/ml
0.59
16
94
64
491
1.31
1.28
3.1
3.0
—
—
—
0
0
132
1103
1.20
1.28
1.6
1.7
—
—
—
0
0
155
1316
1.19
1.26
1.1
1.1
—
—
—
0
0
78
616
1.27
1.26
1.5
1.3
—
—
—
0
0
31
211
1.47
1.25
1.1
1.0
—
—
—
0
0
117
969
1.21
1.24
5.2
5.9
2.1
1.7
%
0.91
107
901
41
296
1.39
1.22
1.1
1.1
—
—
—
0
0
2715
26671
1.09
1.21
14.7
13.5
40.2
40.2
%
0.00
2030
20332
32
221
1.45
1.21
1.1
1.3
1.7
2.0
mmol/l
1.35
32
207
116
964
1.21
1.20
5.3
6.0
0.9
0.9
%
0.01
106
899
30
205
1.47
1.19
1.1
1.1
—
—
—
0
0
106
875
1.22
1.18
3.0
3.7
487.1
1792.9
u/ml
0.58
90
755
108
894
1.21
1.17
2.0
1.7
0.2
0.2
g/l
0.07
95
846
24
157
1.53
1.17
2.2
2.6
621.1
1061.1
u/ml
1.26
24
157
6
127
0.47
1.16
2.2
2.2
—
—
—
0
0
0
33
0.00
1.16
0.0
1.2
—
1.8
—
0
33
36
257
1.41
1.15
2.0
2.7
—
—
—
0
0
66
518
1.28
1.14
3.0
2.5
16.6
16.5
%
0.12
36
258
66
518
1.28
1.14
3.9
3.7
—
—
—
0
0
76
608
1.26
1.13
1.1
1.4
—
—
—
0
0
70
555
1.27
1.12
3.4
3.7
56.8
57.0
%
0.05
70
555
282
2528
1.13
1.12
7.9
8.6
96.0
95.8
%
0.26
270
2442
13
73
1.78
1.10
1.5
1.3
—
—
—
0
0
178
1549
1.16
1.10
6.8
7.5
24.8
24.5
mmol/l
0.59
168
1444
116
974
1.20
1.10
5.4
3.1
—
—
—
0
0
55
424
1.30
1.10
2.8
3.2
—
—
—
0
0
71
566
1.26
1.10
1.0
1.1
2.7
2.4
u/ml
0.07
19
136
82
665
1.24
1.09
2.9
3.6
16.7
1.6
ratio
—
5
58
84
684
1.23
1.08
1.5
1.5
72.5
161.5
pmol/l
2.37
79
674
21
136
1.55
1.08
1.4
1.2
28.7
11.3
u/l
1.04
21
124
43
321
1.34
1.07
6.4
6.8
10.2
11.5
mg/l
1.34
38
297
88
722
1.22
1.06
1.4
1.3
7.3
8.9
iu/ml
—
6
14
17
105
1.62
1.06
1.0
1.0
—
—
—
0
0
43
322
1.34
1.05
2.0
2.8
—
—
—
0
0
21
137
1.54
1.05
1.1
1.1
1412.7
1569.7
miu/ml
0.24
21
137
84
687
1.23
1.05
3.4
3.6
175.9
53.9
mg/l
0.41
70
561
28
195
1.44
1.04
1.1
1.0
—
—
—
0
0
177
1549
1.15
1.03
3.6
3.9
7.4
7.4
ph
0.29
29
189
131
1122
1.17
1.01
3.7
2.2
—
—
—
0
0
27
188
1.44
1.01
1.1
1.1
0.5
3.4
u/ml
—
10
68
72
582
1.24
1.01
1.4
2.3
0.9
0.8
nmol/l
0.16
61
492
89
737
1.21
1.00
1.1
1.1
—
—
—
0
0
74
601
1.24
1.00
1.1
1.1
7.7
6.2
u/ml
0.27
38
318
34
248
1.37
0.99
1.5
1.9
18.6
20.5
ug/l
0.28
34
243
60
476
1.27
0.99
1.3
1.2
—
—
—
0
0
471
4370
1.09
0.99
3.1
2.8
0.7
0.7
ug/l
0.06
306
2729
12
200
0.60
0.98
7.6
17.8
1111.3
1518.2
nmol/l
0.94
12
195
61
486
1.26
0.97
1.0
1.0
3.9
4.2
u/ml
0.05
27
176
0
30
0.00
0.97
0.0
2.9
—
1.1
—
0
21
83
685
1.22
0.97
3.5
3.6
34.5
63.2
mg/l
1.68
69
558
12
198
0.60
0.95
6.7
13.2
643.2
861.9
nmol/l
1.02
12
191
6
27
2.22
0.93
1.2
1.1
—
—
—
0
0
210
1875
1.13
0.93
1.2
1.2
—
—
—
0
0
84
698
1.21
0.93
1.6
1.3
—
—
—
0
0
39
295
1.33
0.92
4.0
4.8
28.5
80.5
u/ml
—
9
85
30
218
1.38
0.91
1.2
1.1
—
—
—
0
0
177
1567
1.14
0.90
3.6
3.9
5.3
5.2
kpa
0.88
162
1461
5
101
0.49
0.89
4.2
4.8
—
—
—
0
0
5
102
0.49
0.89
1.4
1.1
—
—
—
0
0
63
511
1.24
0.88
1.1
1.1
12.7
13.6
au/ml
—
9
35
17
111
1.53
0.87
3.2
3.1
—
—
—
0
0
17
111
1.53
0.87
2.0
2.0
—
—
—
0
0
21
144
1.46
0.87
1.3
1.9
—
—
—
0
0
11
64
1.72
0.86
1.1
1.1
—
—
—
0
0
11
64
1.72
0.86
1.1
1.1
—
—
—
0
0
11
64
1.72
0.86
1.1
1.1
—
—
—
0
0
8
44
1.82
0.85
1.9
1.5
—
—
—
0
0
109
936
1.17
0.85
2.0
2.1
0.9
1.7
ug/l
1.22
98
841
70
578
1.22
0.84
1.0
1.1
2.0
1.4
u/ml
0.23
31
250
119
1032
1.16
0.83
1.3
1.2
—
—
—
0
0
91
773
1.18
0.82
3.2
3.1
—
—
—
0
0
58
708
0.82
0.80
1.4
1.5
—
—
—
0
0
30
224
1.34
0.79
1.7
1.5
—
—
—
0
0
18
257
0.70
0.77
1.1
1.4
14.9
12.3
mmol/l
—
6
64
24
174
1.38
0.76
2.3
2.7
0.1
0.3
e9/l
0.61
24
169
6
34
1.77
0.76
1.5
1.4
—
—
—
0
0
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
151
1342
1.13
0.76
3.4
2.2
—
—
—
0
0
36
279
1.29
0.75
1.1
1.4
—
—
—
0
0
57
691
0.82
0.75
1.4
1.4
—
—
—
0
0
239
2182
1.10
0.75
7.2
7.8
1.2
1.4
mmol/l
2.01
232
2104
5
24
2.08
0.74
1.0
1.1
29.0
1370.6
u/l
—
5
16
50
405
1.24
0.74
1.0
1.0
0.0
0.4
u/ml
—
9
97
82
699
1.18
0.73
1.5
2.3
38.9
38.0
g/l
0.71
69
613
77
904
0.85
0.72
10.0
8.9
—
—
—
0
0
46
567
0.81
0.72
2.7
3.7
25.3
24.7
mg/l
0.04
22
351
11
68
1.62
0.71
1.0
1.0
—
—
—
0
0
129
1141
1.14
0.71
3.9
4.0
—
—
—
0
0
211
1922
1.10
0.70
2.4
2.7
68.2
71.2
e9/l
0.63
159
1449
123
1086
1.14
0.70
1.3
1.3
217.1
223.5
miu/ml
0.07
59
533
7
41
1.71
0.70
3.3
3.9
31.1
42.0
umol/l
—
7
32
352
3286
1.08
0.68
1.6
1.7
—
—
—
0
0
18
127
1.42
0.67
2.4
3.0
7.4
7.4
ph
—
8
41
7
121
0.58
0.67
2.3
2.3
128.7
146.2
nmol/l
—
7
102
2431
23957
1.05
0.67
16.5
15.4
13.6
13.6
%
0.22
2386
23450
29
223
1.30
0.66
1.1
1.2
—
—
—
0
0
58
689
0.84
0.65
1.4
1.4
—
—
—
0
0
350
3284
1.07
0.61
1.7
1.7
—
—
—
0
0
280
2605
1.08
0.61
2.5
2.4
33.0
57.7
u/l
0.75
242
2248
0
20
0.00
0.60
0.0
11.1
—
168.1
—
0
14
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
198.8
—
0
12
282
2630
1.08
0.58
2.5
2.7
1.7
1.8
%
0.62
248
2353
27
210
1.29
0.58
1.1
1.2
—
—
—
0
0
120
1074
1.12
0.58
1.9
2.1
20.9
21.4
s
0.71
108
933
12
81
1.48
0.57
1.0
1.5
—
—
—
0
0
224
2073
1.09
0.57
8.5
9.3
—
—
—
0
0
19
141
1.35
0.56
1.4
1.2
—
—
—
0
0
11
73
1.51
0.56
1.4
1.4
—
—
—
0
0
17
124
1.37
0.55
3.3
3.0
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
12
82
1.47
0.54
1.1
1.1
—
—
—
0
0
69
599
1.16
0.54
3.0
3.9
25.0
24.8
mmol/l
0.16
60
527
54
460
1.18
0.53
1.4
1.6
—
—
—
0
0
158
1447
1.10
0.52
3.4
2.2
—
—
—
0
0
39
323
1.21
0.52
2.2
2.3
—
—
—
0
0
22
170
1.30
0.51
3.5
2.8
42.4
42.6
%
—
9
49
156
1430
1.10
0.51
3.4
2.2
—
—
—
0
0
513
4907
1.05
0.51
1.6
1.6
—
—
—
0
0
52
444
1.17
0.50
1.4
1.4
—
—
—
0
0
6
41
1.46
0.50
1.2
1.3
18.2
23.9
%
—
6
30
41
343
1.20
0.50
1.8
1.5
—
—
—
0
0
58
501
1.16
0.49
1.1
1.1
—
—
—
0
0
157
1442
1.09
0.49
3.4
2.2
—
—
—
0
0
111
1002
1.11
0.49
4.1
4.0
24.9
24.8
mmol/l
0.04
99
939
191
2058
0.92
0.49
1.4
1.4
—
—
—
0
0
12
85
1.41
0.46
4.5
12.1
—
—
—
0
0
39
328
1.19
0.46
1.2
1.4
1150.7
299.7
pmol/l
0.59
31
257
16
120
1.33
0.46
1.3
1.1
—
4.3
—
0
6
52
600
0.86
0.45
1.9
2.0
—
—
—
0
0
25
201
1.25
0.45
1.6
2.3
0.8
2.0
u/field
1.78
16
92
15
112
1.34
0.44
1.5
2.3
0.9
1.5
ug/l
0.75
15
103
153
1413
1.09
0.44
1.7
2.1
—
—
—
0
0
7
51
1.37
0.44
1.1
1.1
—
—
—
0
0
57
498
1.15
0.43
1.5
1.4
27.9
25.0
u/l
0.23
45
413
33
275
1.20
0.43
2.7
1.4
286.4
281.3
mosm/kgh2o
0.42
24
214
57
650
0.87
0.43
1.2
1.2
—
—
—
0
0
20
157
1.28
0.43
1.8
1.3
132.3
133.2
nmol/l
0.05
20
157
11
78
1.41
0.43
1.5
1.6
—
—
—
0
0
29
239
1.22
0.42
1.4
1.4
1530.7
2505.2
e6/l
0.78
20
167
8
56
1.43
0.42
5.5
7.3
—
—
—
0
0
5
32
1.56
0.42
1.2
1.2
—
—
—
0
0
20
158
1.27
0.41
1.3
1.4
—
—
—
0
0
20
158
1.27
0.41
1.5
1.6
27.2
26.1
umol/l
0.06
20
150
234
2204
1.07
0.41
6.3
7.8
8.2
9.0
mmol/l
1.19
223
2111
5
33
1.52
0.41
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
22
177
1.24
0.40
2.1
1.4
1674.4
2084.6
ml
—
10
35
112
1221
0.91
0.40
3.6
3.2
—
—
—
0
0
7
103
0.68
0.39
1.9
2.6
—
—
—
0
0
47
538
0.87
0.39
2.8
3.1
—
—
—
0
0
37
316
1.17
0.38
1.1
1.4
—
—
—
0
0
30
356
0.84
0.38
2.3
2.4
—
—
—
0
0
139
1289
1.08
0.38
10.5
10.8
24.6
24.3
mmol/l
0.54
133
1214
11
80
1.38
0.38
1.3
1.1
—
—
—
0
0
11
80
1.38
0.38
1.3
1.2
—
—
—
0
0
28
334
0.84
0.38
1.1
1.2
—
—
—
0
0
62
552
1.13
0.38
2.4
3.0
32.1
36.8
umol/l
0.93
52
477
30
252
1.19
0.37
3.2
3.2
—
—
—
0
0
5
37
1.35
0.37
6.4
3.3
—
—
—
0
0
33
385
0.86
0.36
2.7
3.1
0.9
0.8
nmol/l
0.15
27
303
23
277
0.83
0.35
1.1
1.2
—
—
—
0
0
6
44
1.36
0.34
1.3
1.5
—
—
—
0
0
138
1288
1.07
0.34
2.6
2.8
0.4
0.3
e6/l
0.11
132
1249
20
163
1.23
0.34
2.5
3.4
—
—
—
0
0
100
921
1.09
0.34
3.4
3.4
0.2
0.3
g/l
1.19
54
411
25
209
1.20
0.34
1.5
1.4
35312.8
112399.1
e6/l
1.11
16
124
12
91
1.32
0.33
2.0
2.3
—
—
—
0
0
30
257
1.17
0.32
1.2
1.2
—
—
—
0
0
57
633
0.90
0.31
1.3
1.3
—
—
—
0
0
26
220
1.18
0.31
1.2
1.5
—
—
—
0
0
22
183
1.20
0.31
1.0
1.1
0.1
6.2
nmol/l
—
5
37
7
96
0.73
0.30
1.1
1.1
—
—
—
0
0
7
98
0.71
0.30
1.0
1.0
—
—
—
0
0
10
131
0.76
0.30
1.1
2.1
18.9
80.0
ug/l
—
10
117
13
102
1.28
0.30
1.0
4.1
290.3
64.6
mg/l
—
6
73
17
139
1.22
0.29
1.3
1.6
—
—
—
0
0
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
8
62
1.29
0.28
1.9
2.3
—
—
—
0
0
11
85
1.30
0.28
1.2
1.3
—
—
—
0
0
81
749
1.08
0.27
1.6
1.9
5.1
4.7
iu/l
0.11
26
272
97
1038
0.93
0.26
1.8
1.8
1.4
1.5
g/l
0.76
85
906
5
71
0.70
0.26
5.0
1.5
13.5
12.8
g/l
—
5
52
10
127
0.79
0.25
1.5
1.6
—
—
—
0
0
21
179
1.17
0.25
1.3
1.1
—
—
—
0
0
26
226
1.15
0.24
1.1
1.2
—
275.0
—
0
6
24
208
1.15
0.24
1.4
1.5
—
—
—
0
0
19
222
0.86
0.23
1.0
1.0
—
—
—
0
0
5
38
1.32
0.23
6.2
2.8
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
50.5
111.6
ng/l
—
5
38
31
275
1.13
0.23
2.6
4.3
—
—
—
0
0
22
190
1.16
0.23
1.1
1.1
0.5
1.3
u/ml
—
7
54
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
5
40
1.25
0.22
6.6
8.6
—
—
—
0
0
23
200
1.15
0.22
1.7
1.5
—
68.2
—
0
21
11
135
0.81
0.22
1.0
1.1
—
—
—
0
0
22
191
1.15
0.21
1.5
1.5
—
—
—
0
0
44
482
0.91
0.21
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
2.5
—
0
10
65
604
1.08
0.21
2.3
2.6
75.0
121.3
ug/min
0.64
35
377
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
174
1814
0.96
0.21
1.6
1.7
—
—
—
0
0
5
43
1.16
0.21
1.4
1.1
—
—
—
0
0
15
177
0.85
0.21
1.4
1.2
—
—
—
0
0
92
867
1.06
0.21
1.1
1.2
—
—
—
0
0
52
479
1.09
0.21
1.1
1.1
17.8
1217.0
iu/ml
0.55
17
112
1104
10897
1.02
0.20
2.6
2.6
—
—
—
0
0
0
14
0.00
0.20
0.0
5.0
—
412.7
—
0
14
32
288
1.11
0.20
2.2
2.2
33.6
32.2
pg
0.97
32
288
70
655
1.07
0.19
1.2
1.4
7.1
20.0
e6/l
1.35
56
501
70
655
1.07
0.19
1.2
1.4
355.4
1324.1
e6/l
1.05
61
526
14
119
1.18
0.17
1.4
1.2
—
—
—
0
0
24
214
1.12
0.17
2.1
2.7
428.7
714.0
e6/l
—
9
87
7
63
1.11
0.17
1.3
2.8
—
—
—
0
0
51
475
1.07
0.17
1.2
1.2
2.8
4.8
u/ml
1.39
26
202
23
205
1.12
0.17
1.4
1.4
4.8
6.4
mmol/l
1.60
23
191
10
120
0.83
0.16
1.4
1.6
—
—
—
0
0
345
3371
1.03
0.16
1.5
1.4
—
—
—
0
0
735
7245
1.02
0.16
1.6
1.6
1.4
1.4
mmol/l
0.29
642
6171
47
502
0.94
0.14
1.1
1.2
—
—
—
0
0
22
244
0.90
0.14
1.3
1.4
68.0
174.7
pmol/l
0.42
12
78
42
450
0.93
0.14
2.6
3.1
6.7
7.4
mmol/l
1.69
42
437
29
316
0.92
0.14
1.8
1.5
—
—
—
0
0
29
316
0.92
0.14
1.8
1.5
—
—
—
0
0
29
316
0.92
0.14
1.8
1.5
—
—
—
0
0
29
316
0.92
0.14
1.8
1.5
—
—
—
0
0
102
979
1.04
0.14
4.5
4.8
—
—
—
0
0
33
305
1.08
0.13
1.1
1.6
—
—
—
0
0
63
598
1.05
0.13
1.4
1.4
—
—
—
0
0
818
8090
1.01
0.13
1.5
1.5
—
—
—
0
0
9
106
0.85
0.13
1.3
1.1
—
—
—
0
0
9
107
0.84
0.13
1.7
1.7
—
—
—
0
0
334
3404
0.98
0.13
1.3
1.3
—
—
—
0
0
15
133
1.13
0.12
3.5
2.7
1953.7
1955.9
ml
0.00
15
120
17
189
0.90
0.12
1.1
1.1
1.1
1.0
ratio
—
5
74
55
578
0.95
0.11
4.6
4.0
—
—
—
0
0
12
105
1.14
0.11
1.2
1.2
—
—
—
0
0
186
1819
1.02
0.10
3.1
3.3
4.7
4.6
kpa
0.16
181
1758
5
44
1.14
0.10
1.0
1.7
—
—
—
0
0
42
442
0.95
0.09
1.0
1.1
1.5
2.7
u/ml
1.02
23
215
65
625
1.04
0.09
6.2
3.0
—
—
—
0
0
176
1723
1.02
0.09
2.8
2.7
—
—
—
0
0
218
2220
0.98
0.09
3.6
4.0
1.9
2.0
mmol/l
0.12
182
1791
6
58
1.03
0.08
3.5
2.0
—
—
—
0
0
53
552
0.96
0.08
1.5
1.4
103.1
116.0
u/ml
0.51
19
110
20
185
1.08
0.08
1.3
1.2
—
—
—
0
0
59
612
0.96
0.08
1.4
1.2
254.2
266.1
u/ml
0.09
35
374
6
72
0.83
0.07
1.7
2.3
—
—
—
0
0
37
388
0.95
0.07
3.0
3.6
0.9
1.3
%
1.00
32
314
46
479
0.96
0.07
2.5
3.0
1.3
1.5
mmol/l
1.57
46
462
314
3103
1.01
0.07
7.0
7.4
104.6
104.5
mmol/l
0.13
309
3041
9
87
1.03
0.07
1.2
1.3
—
—
—
0
0
8
95
0.84
0.06
1.0
1.7
—
—
—
0
0
21
223
0.94
0.06
3.0
3.1
62.7
41.7
mg/l
0.26
14
166
220
2227
0.99
0.05
3.5
4.0
5.9
5.9
kpa
0.60
215
2158
123
1209
1.02
0.05
3.7
4.3
24.4
24.2
mmol/l
0.31
111
1099
11
100
1.10
0.05
2.6
2.7
—
—
—
0
0
23
218
1.06
0.05
1.7
1.5
—
—
—
0
0
123
1210
1.02
0.05
1.6
1.8
—
—
—
0
0
44
426
1.03
0.05
4.0
5.4
356.3
369.8
umol/l
0.33
39
375
24
252
0.95
0.05
1.0
1.0
—
—
—
0
0
2479
24829
0.99
0.04
17.8
16.1
332.7
332.9
g/l
0.26
2463
24648
19
201
0.94
0.04
1.8
1.9
7.2
6.7
mmol/l
0.23
14
137
25
261
0.96
0.04
1.9
2.5
—
—
—
0
0
12
111
1.08
0.04
1.0
1.0
—
—
—
0
0
42
408
1.03
0.04
1.4
1.4
58.7
65.8
mmol/l
0.49
34
329
11
118
0.93
0.02
3.4
2.4
—
—
—
0
0
51
500
1.02
0.02
1.1
1.1
—
—
—
0
0
19
197
0.96
0.01
1.7
2.2
—
—
—
0
0
13
124
1.05
0.00
1.5
1.3
—
—
—
0
0
13
136
0.96
0.00
2.1
3.2
—
32.4
—
0
12
14
146
0.96
0.00
1.0
1.3
—
77.0
%
—
0
18
15
156
0.96
0.00
1.7
1.4
5.3
5.7
mmol/l
0.88
15
150
21
204
1.03
0.00
2.1
2.7
10.5
11.4
%
0.38
21
204
11
112
0.98
0.00
2.6
1.8
—
—
—
0
0
21
205
1.02
0.00
1.3
1.3
—
1.5
—
0
10
24
239
1.00
0.00
2.6
3.4
49.5
56.1
%
0.67
17
163
41
409
1.00
0.00
1.2
1.2
—
—
—
0
0
103
1033
1.00
0.00
1.4
1.4
—
—
—
0
0
21
207
1.01
0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
170.3
—
0
6
5
51
0.98
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
51
0.98
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
1.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
2626.6
—
0
9
7
72
0.97
0.00
1.3
2.2
13.4
16.6
umol/l
—
7
72
0
7
0.00
0.00
0.0
4.4
—
4.5
—
0
7
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
5
56
0.89
0.00
1.4
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_BONE_CARTILAGE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_CARTILAGE 1.057 [0.93, 1.21] 0.407
Birth year 0.999 [0.99, 1.01] 0.714

During the follow-up period (1.1.1998 — 31.12.2019), 530 out of 7903 females with CD2_BENIGN_BONE_CARTILAGE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_CARTILAGE 1.056 [0.93, 1.2] 0.408
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 589 out of 7613 males with CD2_BENIGN_BONE_CARTILAGE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BONE_CARTILAGE.

N-year risk Females Males
1 0.093% 0.165%
5 0.603% 1.185%
10 1.661% 2.905%
15 3.341% 5.841%
20 6.078% 9.778%

Relationships between endpoints

Index endpoint: CD2_BENIGN_BONE_CARTILAGE – Benign neoplasm of bone and articular cartilage

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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