chondrosarcoma: A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.
Benign neoplasm of bone and articular cartilage
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_BONE_CARTILAGE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2585 |
4. Check minimum number of eventsNone |
2585 |
5. Include endpoints |
3576 |
6. Filter based on genotype QC (FinnGen only) |
3482 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10-D36
- Name in latin
- Neoplasma benignum ossis sive cartilaginis articularis
Benign neoplasm of bone and articular cartilage
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 27315 | 13494 | 13693 |
| Only index persons | 25120 | 12600 | 12520 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.39 | 0.38 |
| Only index persons | 0.47 | 0.46 | 0.48 |
| Median age at first event (years) | |||
| Whole population | 31.98 | 37.34 | 26.57 |
| Only index persons | 30.96 | 36.54 | 25.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3482 | 2091 | 1391 |
| Unadjusted period prevalence (%) | 0.70 | 0.74 | 0.64 |
| Median age at first event (years) | 40.91 | 41.03 | 40.73 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3576
- Matched controls
- 35760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
2424.4
307.7
449
*
9102
FHL
Trepanation or removal of the local bone process
67.4
307.7
297
48
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
38.6
307.7
459
136
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
6162.1
307.7
944
*
D16.49
ICD-10 Finland
Bones of skull and face
+∞
302.5
286
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
16.8
291.7
248
158
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
967.7
277.8
269
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
96.3
249.8
130
14
D16.3
ICD-10 Finland
Benign neoplasm: Short bones of lower limb
+∞
229.7
218
*
21306
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis inferioris
+∞
219.0
208
*
2137A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Long bones of lower limb
+∞
184.0
175
*
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
1921.6
180.7
174
*
NHR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of ankle or foot
47.7
159.2
93
20
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
34.1
146.2
93
28
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
32.2
145.2
94
30
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
1304.7
130.0
126
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
32.0
106.4
69
22
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
35.6
100.2
63
18
21307
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis inferioris
+∞
98.4
94
*
2135A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of upper limb
+∞
92.1
88
*
21303
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium longorum extremitatis superioris et scapulae
+∞
90.0
86
*
AAP10
NOMESCO Finland
Extirpation of a skull lesion
143.3
79.3
84
6
D16.6
ICD-10 Finland
Benign neoplasm: Vertebral column
764.4
76.6
75
*
9101
FHL
Bone biopsy
33.1
76.3
49
15
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
4.9
72.1
161
338
2138A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of lower limb
+∞
67.9
65
*
D16.50
ICD-10 Finland
Benign tumor of the mandibular bone or cartilage
+∞
65.8
63
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.0
65.8
143
293
21304
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis superioris
+∞
62.7
60
*
D16.51
ICD-10 Finland
Benign tumor of the mandibular bone with urpsrung in teeth
+∞
57.4
55
*
NDK10
NOMESCO Finland
Incision or excision of a bone of hand
18.1
53.4
43
24
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
4.8
53.4
121
257
NF3AA
NOMESCO Finland
Femur X-ray examination
5.0
52.3
114
234
21309
ICD-8 Finland
Benign neoplasm of bone and cartilage, Unspecified
+∞
50.1
48
*
D16.7
ICD-10 Finland
Benign neoplasm: Ribs, sternum and clavicle
484.3
48.5
48
*
D16.40
ICD-10 Finland
Orbital bone
+∞
45.9
44
*
2130A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bones of skull and face
+∞
42.8
41
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.1
41.5
439
2234
9103
FHL
Partial or complete bone removal
14.0
39.1
36
26
N02AX02
ATC
tramadol; systemic, rectal
1.6
38.9
1439
10581
21308
ICD-8 Finland
Benign neoplasm of bone and cartilage, Loco alio sive multiplici
+∞
37.6
36
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
4.0
37.4
108
277
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
11.6
36.9
38
33
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.1
36.3
357
1764
2134A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Scapula and long bones of upper limb
+∞
34.4
33
*
M79.6
ICD-10 Finland
Pain in limb
1.5
33.5
1435
10803
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.1
33.3
140
460
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
33.2
1525
11652
9104
FHL
Autogenous bone graft
171.6
32.7
34
*
N03AX16
ATC
[U] pregabalin
1.7
32.3
785
5157
D16
ICD-10 Finland
Benign neoplasm of bone and articular cartilage
166.5
31.7
33
*
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
6.7
29.7
47
71
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
5.2
29.5
60
116
M01AH05
ATC
etoricoxib; oral
1.5
29.5
2142
17835
M25.5
ICD-10 Finland
Pain in joint
1.5
29.4
1130
8245
EDA10
NOMESCO Finland
Biopsy of mandible
11.6
29.2
30
26
ZXA05
NOMESCO Finland
Left side
1.6
28.5
757
5066
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
28.0
1255
9441
ZZH40
NOMESCO Finland
Substitute of bone
5.3
27.5
55
105
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
26.8
265
1308
NFK10
NOMESCO Finland
Fenestration or partial or total excision of bone of femur
75.7
26.8
30
*
N02BE01
ATC
paracetamol; systemic, rectal
1.7
26.4
3050
27699
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.5
26.1
173
722
21302
ICD-8 Finland
Benign neoplasm of bone and cartilage, Costae, sterni, claviculae
+∞
26.1
25
*
NGK05
NOMESCO Finland
Partial or total excision of bone of lower leg
40.4
25.8
32
8
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.7
25.7
83
231
21300
ICD-8 Finland
Benign neoplasm of bone and cartilage, Mandibulae (detibus inclusis)
+∞
25.0
24
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
24.6
1381
10790
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
4.8
24.5
55
116
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
24.5
1425
11208
AA1AD
NOMESCO Finland
CT of head and brain
1.6
23.9
780
5447
NG4AA
NOMESCO Finland
Lower leg X-ray examination
2.7
23.5
126
474
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.6
22.9
616
4112
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.3
22.7
84
256
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
3.1
22.4
93
304
2139X
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bone and articular cartilage, site unspecified
+∞
21.9
21
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
21.8
341
1966
EFA10
NOMESCO Finland
Excision of lesion of jaws
38.9
21.7
27
7
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
3.4
21.5
76
225
S18
ICPC
Laceration/cut
1.4
21.3
1405
11221
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
110.7
20.6
22
*
M54.5
ICD-10 Finland
Low back pain
1.4
20.5
1195
9319
M85.4
ICD-10 Finland
Solitary bone cyst
18.4
20.4
31
17
N06AX21
ATC
duloxetine; oral
1.7
20.4
408
2522
X58
ICD-10 Finland
Exposure to other specified factors
1.6
20.4
491
3184
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
4.5
20.1
49
111
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.6
19.9
115
450
21305
ICD-8 Finland
Benign neoplasm of bone and cartilage, Pelvis, sacri, coccygis
+∞
19.8
19
*
J01DB01
ATC
cefalexin; oral
1.5
19.7
2828
25681
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
19.6
3168
29498
A02BC02
ATC
pantoprazole; systemic
1.4
19.6
2184
18944
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
19.5
855
6312
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
19.3
291
1658
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
19.2
806
5898
SPAT1153
SPAT
Removal of sutures
1.4
19.0
931
7013
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
18.9
1172
9206
M03BX02
ATC
tizanidine; oral
1.4
18.9
2101
18162
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
15.1
18.4
30
20
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
18.2
276
1574
A02BC05
ATC
esomeprazole; systemic
1.4
18.1
1269
10158
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
18.0
831
6186
Q78.6
ICD-10 Finland
Multiple congenital exostoses
52.8
17.9
21
*
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
3.6
17.9
58
162
ZZH20
NOMESCO Finland
Graft of patients own bone
7.0
17.8
27
39
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
17.8
404
2577
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
17.7
1105
8668
WX320
NOMESCO Finland
Spinalanesthesy
1.5
17.7
716
5194
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
17.6
217
1158
ZXA00
NOMESCO Finland
Right side
1.5
17.5
761
5597
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
2.6
17.4
97
373
J01AA02
ATC
doxycycline; systemic
1.4
17.2
2546
22868
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
17.1
280
1634
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
16.9
606
4287
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
16.8
775
5757
D16.41
ICD-10 Finland
Benign tumor of the maxillary bone originating in teeth
+∞
16.7
16
*
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
23.1
16.4
23
10
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.7
16.3
312
1902
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
6.3
16.3
27
43
R51.80
ICD-10 Finland
Headache
1.5
16.0
517
3573
NG1AD
NOMESCO Finland
Knee CT examination
3.3
15.7
59
182
R52.9
ICD-10 Finland
Pain, unspecified
1.7
15.7
306
1875
2131A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Lower jaw bone
+∞
15.6
15
*
UKC02
NOMESCO Finland
Cystoscopy
1.6
15.6
405
2666
Q78.48
ICD-10 Finland
Enchondromatosis
85.5
15.6
17
*
N03AX12
ATC
[U] gabapentin; oral
1.5
15.6
503
3477
M01AB05
ATC
diclofenac; systemic, rectal
1.3
15.4
2169
19143
M01AE02
ATC
naproxen; oral, rectal
1.3
15.3
1876
16219
WX204
NOMESCO Finland
Axillary plexus blockaced
2.3
15.3
120
541
M85.0
ICD-10 Finland
Fibrous dysplasia (monostotic)
45.2
15.1
18
*
J01DA01
ATC
[U] cefalexin
1.3
15.0
2011
17586
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
14.7
262
1566
UJF32
NOMESCO Finland
Coloscopy
1.4
14.7
731
5488
D16.5
ICD-10 Finland
Benign neoplasm: Lower jaw bone
+∞
14.6
14
*
2136A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Pelvic bones, sacrum and coccyx
+∞
14.6
14
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
80.4
14.6
16
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
80.4
14.6
16
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
14.5
1067
8539
NFK99
NOMESCO Finland
Other operation on bone of femur
36.2
14.4
18
5
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
14.4
753
5699
J01FF01
ATC
clindamycin; systemic
1.4
14.4
825
6345
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
12.6
14.4
25
20
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
14.3
1139
9222
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
14.2
692
5171
M67.4
ICD-10 Finland
Ganglion
1.8
14.2
222
1279
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
14.1
617
4520
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.0
14.1
163
852
S62.6
ICD-10 Finland
Fracture of other finger
2.0
14.1
153
783
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.6
14.0
339
2194
M01AH01
ATC
celecoxib; oral
1.5
14.0
503
3551
E0000UV, ,
ATC
1.3
13.9
1303
10790
N02BF02
ATC
pregabalin; oral
1.9
13.9
189
1042
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.6
13.8
297
1868
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
13.7
340
2211
SPAT1229
SPAT
Assessment of need for aid
1.8
13.6
200
1130
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
13.6
888
6965
L08
ICPC
Shoulder symptom/complaint
1.4
13.6
649
4831
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.6
13.6
295
1859
21301
ICD-8 Finland
Benign neoplasm of bone and cartilage, Columnae vertebralis (sacro et coccyge exclusis)
+∞
13.5
13
*
R01AD12
ATC
fluticasone furoate; nasal
1.3
13.4
1048
8442
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
13.3
727
5535
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
13.2
557
4051
R03AC02
ATC
salbutamol; inhalant
1.3
13.1
1774
15406
J01FA09
ATC
clarithromycin; systemic
1.3
13.1
993
7957
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
13.1
821
6389
TAKUU, ,
NOMESCO Finland
4.0
13.1
36
90
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
13.0
1712
14807
N02AA05
ATC
oxycodone; systemic
1.5
13.0
441
3073
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
2.6
12.9
75
296
ZXE00
NOMESCO Finland
One hour or less
1.3
12.8
1189
9808
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
12.8
2391
21649
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.6
12.7
326
2136
R01AD09
ATC
mometasone; nasal
1.3
12.7
1485
12635
WX202
NOMESCO Finland
Supraclavicular plexus blockade
3.1
12.6
52
170
M01AX17
ATC
nimesulide; oral
1.4
12.6
658
4968
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
12.5
440
3088
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
12.5
536
3908
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
12.5
1319
11064
P01AB01
ATC
metronidazole; oral, rectal
1.3
12.3
1239
10319
XKD00
NOMESCO Finland
Uroflowmetry
1.5
12.3
360
2431
ZZH31
NOMESCO Finland
Bone allograft, small pieces
4.1
12.3
33
81
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
9.0
12.2
25
28
NK6DT
NOMESCO Finland
Bone biopsy with MRI guidance
37.7
12.2
15
*
L13
ICPC
Hip symptom/complaint
1.4
12.2
495
3572
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
13.4
11.9
20
15
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.2
11.9
96
439
L15
ICPC
Knee symptom/complaint
1.4
11.9
692
5315
NHR30
NOMESCO Finland
Complete excision of soft tissue tumour of ankle or foot
46.8
11.9
14
*
N02BF01
ATC
gabapentin; oral
1.6
11.8
251
1573
SPAT1263
SPAT
Sampling
1.3
11.8
1271
10669
M02AA07
ATC
piroxicam; topical
1.3
11.8
1004
8164
J02AC01
ATC
fluconazole; systemic
1.3
11.8
1236
10339
M48.0
ICD-10 Finland
Spinal stenosis
1.6
11.7
308
2030
M85.8
ICD-10 Finland
Other specified disorders of bone density and structure
5.5
11.6
22
40
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
65.2
11.6
13
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
11.5
783
6157
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
1.8
11.5
182
1052
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
11.5
11
*
2133A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Ribs, sternum and clavicle
+∞
11.5
11
*
A02BC03
ATC
lansoprazole; oral
1.3
11.4
813
6434
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
11.3
1530
13196
R01AD08
ATC
fluticasone; nasal
1.3
11.2
903
7276
L03
ICPC
Low back symptom/complaint
1.3
11.1
842
6722
ND3CG
NOMESCO Finland
Extensive MRI of fingers
20.1
11.1
16
8
SFA10
NOMESCO Finland
One-surface restoration
1.3
11.1
1802
15879
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
11.1
253
1613
B01AB05
ATC
enoxaparin; parenteral
1.3
11.1
867
6956
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.6
11.1
291
1919
J01FA10
ATC
azithromycin; systemic
1.3
11.0
1913
16988
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
10.9
719
5619
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.3
10.9
835
6673
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
10.9
1796
15840
NHR99
NOMESCO Finland
Other operation for tumour of ankle or foot
43.4
10.9
13
*
N06AX11
ATC
mirtazapine; oral
1.3
10.8
1014
8337
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
10.8
525
3910
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
10.8
1661
14529
M01AC06
ATC
meloxicam; systemic, rectal
1.3
10.7
1061
8783
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
2.8
10.7
51
182
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
10.7
180
1061
75665
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Exostosis cartilaginea multiplex
60.2
10.6
12
*
NFR99
NOMESCO Finland
Other operation for tumour of hip or thigh
+∞
10.4
10
*
L17
ICPC
Foot/toe symptom/complaint
1.3
10.3
827
6649
9109
FHL
Other measure in this category
8.8
10.3
21
24
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.2
10.2
81
369
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.0
10.1
112
578
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
10.1
311
2121
H02AB06
ATC
prednisolone; systemic
1.3
10.1
1411
12168
R06AE07
ATC
cetirizine; oral
1.3
10.1
1396
12024
A02BC01
ATC
omeprazole; systemic
1.3
10.0
750
5969
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.1
10.0
88
418
L12
ICPC
Hand/finger symptom/complaint
1.4
10.0
480
3565
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.9
10.0
117
617
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
9.9
851
6896
SAA04
NOMESCO Finland
Special examination of mouth
1.7
9.9
165
969
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.5
9.8
326
2258
R01AD58
ATC
fluticasone, combinations; nasal
1.3
9.8
794
6388
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
2.3
9.7
68
293
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
9.7
704
5572
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
9.7
176
1059
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
2.4
9.7
63
263
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.8
9.7
150
863
WX002
NOMESCO Finland
Sedation and analgesia
1.4
9.7
519
3924
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.7
9.6
187
1147
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.5
2405
22137
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
9.5
188
1159
SFA30
NOMESCO Finland
Three-surface restoration
1.3
9.4
1310
11260
-, ,
ICD-10 Finland
2.3
9.4
67
291
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.7
9.4
157
923
M89.3
ICD-10 Finland
Hypertrophy of bone
17.6
9.4
14
8
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
9.4
240
1573
D16.9
ICD-10 Finland
Benign neoplasm: Bone and articular cartilage, unspecified
+∞
9.4
9
*
WX702
NOMESCO Finland
Supraglottic ventilation device
1.7
9.3
165
986
J01EA01
ATC
trimethoprim; systemic
1.3
9.3
722
5765
J01MA02
ATC
ciprofloxacin; systemic
1.3
9.2
1090
9191
K02.1
ICD-10 Finland
Caries of dentine
1.2
9.2
1947
17527
M85.6
ICD-10 Finland
Other cyst of bone
13.7
9.2
15
11
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
2.0
9.2
97
494
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.7
9.1
157
931
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
9.1
267
1804
GAE06
NOMESCO Finland
Excision of lesion of chest wall
11.5
9.1
16
14
Z01.2
ICD-10 Finland
Dental examination
1.2
9.0
1447
12624
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
36.8
9.0
11
*
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
36.8
9.0
11
*
ND2AA, ,
SPAT
1.7
9.0
152
897
M01AH03
ATC
valdecoxib; oral
1.7
9.0
165
997
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
8.9
425
3151
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.1
8.8
84
412
GA1CG
NOMESCO Finland
Extensive MRI of chest
10.7
8.8
16
15
A01
ICPC
Pain general/multiple sites
1.5
8.8
253
1703
R93.7
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
9.5
8.8
17
18
K07.60
ICD-10 Finland
Snapping jaw
1.7
8.7
162
981
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
7.2
8.7
20
28
M12.2
ICD-10 Finland
Villonodular synovitis (pigmented)
14.0
8.7
14
10
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
8.6
591
4633
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
8.6
643
5102
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
8.6
204
1314
NB1DG
NOMESCO Finland
Shoulder and humerus very extensive MRI examination with high intensity magnet
3.3
8.6
32
99
XX2RW, ,
NOMESCO Finland
3.0
8.6
37
125
N06AA09
ATC
amitriptyline; systemic
1.5
8.6
250
1686
R42
ICD-10 Finland
Dizziness and giddiness
1.3
8.6
590
4627
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
8.6
304
2135
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.6
8.6
178
1111
NFA20
NOMESCO Finland
Exploration of hip joint or femur
16.3
8.5
13
8
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
8.5
380
2782
J01CA04
ATC
amoxicillin; systemic
1.3
8.5
2739
25719
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
3.5
8.5
28
80
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.6
8.5
176
1097
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
27.6
8.5
11
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
27.6
8.5
11
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
8.5
529
4091
J01FA06
ATC
roxithromycin; oral
1.2
8.4
1179
10113
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.9
8.4
96
503
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
8.4
220
1451
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
8.4
261
1786
ZXD20
NOMESCO Finland
Day surgery
1.4
8.4
365
2663
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
8.3
372
2724
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
8.3
8
*
D16.91
ICD-10 Finland
Benign tumor in unspecified localization in bone with urpsrung in teeth
+∞
8.3
8
*
G44.2
ICD-10 Finland
Tension-type headache
1.4
8.3
407
3030
L28
ICPC
Limited function/disability (L)
1.4
8.3
415
3100
SPAT1312
SPAT
General health counselling
1.3
8.3
926
7739
ND2CG
NOMESCO Finland
Extensive MRI of hand
7.1
8.2
19
27
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.4
8.2
306
2169
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
8.2
347
2518
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.1
436
3292
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
33.4
8.1
10
*
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
11.7
8.1
14
12
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
8.1
922
7720
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
8.0
806
6644
R4110
NOMESCO Finland
Physiotherapy
1.3
8.0
765
6267
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
2.8
8.0
38
136
H02
ICPC
Hearing complaint
1.4
8.0
316
2265
Z04.3
ICD-10 Finland
Examination and observation following other accident
2.2
8.0
62
281
R53
ICD-10 Finland
Malaise and fatigue
1.3
7.9
678
5474
SFA20
NOMESCO Finland
Two-surface restoration
1.2
7.9
1902
17228
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.5
7.9
221
1479
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.9
708
5753
H02AB04
ATC
methylprednisolone; systemic
1.4
7.9
387
2882
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.1
7.8
67
316
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
7.8
165
1035
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
2.0
7.8
80
404
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
10.8
7.8
14
13
M54.2
ICD-10 Finland
Cervicalgia
1.5
7.8
233
1583
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.0
7.7
80
406
WX203
NOMESCO Finland
Infraclavicular plexus blockade
2.1
7.6
71
346
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.8
7.6
112
637
WX402
NOMESCO Finland
General anaesthesia
1.3
7.6
617
4947
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
7.6
406
3065
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
25.1
7.6
10
*
NC1BG
NOMESCO Finland
Elbow MRI examination with high intensity magnet
3.6
7.6
24
67
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
3.8
7.5
22
58
G47.3
ICD-10 Finland
Sleep apnoea
1.3
7.5
640
5164
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.7
7.5
147
905
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.4
7.5
301
2165
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
2.7
7.5
39
147
M22.4
ICD-10 Finland
Chondromalacia patellae
1.9
7.4
96
524
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
7.4
351
2595
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.3
7.4
54
238
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.5
7.4
231
1581
9105
FHL
Homogeneous or heterogeneous bone graft, e.g., joint graft
80.3
7.4
8
*
R50.9
ICD-10 Finland
Fever, unspecified
1.4
7.4
413
3137
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.4
7.4
334
2451
N30.0
ICD-10 Finland
Acute cystitis
1.3
7.4
430
3288
NG1BG, ,
SPAT
1.7
7.4
121
710
1220
FHL
Arthroscopy
1.8
7.3
107
607
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.5
7.3
192
1267
P01BA02
ATC
hydroxychloroquine; oral
1.5
7.3
224
1528
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
2.5
7.3
43
172
M25.7
ICD-10 Finland
Osteophyte
8.4
7.3
15
18
L16
ICPC
Ankle symptom/complaint
1.4
7.3
331
2431
R4120
NOMESCO Finland
Occupational therapy
1.6
7.3
182
1188
D16.4
ICD-10 Finland
Benign neoplasm: Bones of skull and face
+∞
7.3
7
*
NBK10
NOMESCO Finland
Partial or total excision of bone of shoulder or upper arm, humerus
+∞
7.3
7
*
2132A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Vertebral column, excluding sacrum and coccyx
+∞
7.3
7
*
C05AA08
ATC
fluocortolone; rectal, topical
1.4
7.2
359
2678
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
7.2
870
7316
J20
ICD-10 Finland
Acute bronchitis
1.4
7.2
279
1994
Q78.1
ICD-10 Finland
Polyostotic fibrous dysplasia
30.1
7.1
9
*
EHA10
NOMESCO Finland
Biopsy of palate
3.6
7.1
23
65
M88.9
ICD-10 Finland
Paget disease of bone, unspecified
20.0
7.1
10
5
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
2.6
7.1
38
145
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.0
7.1
78
404
WYA10
NOMESCO Finland
Emergency care or similar visit
1.5
7.1
216
1472
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
7.9
7.1
15
19
XJH00
NOMESCO Finland
Transanal ultrasonography
1.7
7.1
115
673
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
2.2
7.1
56
256
NC2AA
NOMESCO Finland
Forearm X-ray examination
2.4
7.1
46
193
M85.9
ICD-10 Finland
Disorder of bone density and structure, unspecified
8.8
7.0
14
16
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.6
7.0
175
1142
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.0
7.0
67
330
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
7.0
288
2079
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.5
7.0
190
1264
S06.0
ICD-10 Finland
Concussion
1.4
7.0
296
2148
L93
ICPC
Tennis elbow
2.8
7.0
33
118
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.0
799
6677
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
6.9
1136
9862
NB6AA
NOMESCO Finland
Humerus X-ray examination
2.2
6.9
55
252
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
1.6
6.9
164
1058
A06AC51
ATC
ispaghula, combinations; oral
1.7
6.9
124
746
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.5
6.9
190
1268
K59.0
ICD-10 Finland
Constipation
1.7
6.9
134
824
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.5
6.9
217
1490
S04
ICPC
Lump/swelling localized
1.4
6.8
284
2054
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
1.9
6.8
84
452
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.4
6.8
258
1835
NDK00
NOMESCO Finland
Excision or incsion of a bone of wrist
6.7
6.8
16
24
M79.1
ICD-10 Finland
Myalgia
1.3
6.8
425
3286
JN4AD
NOMESCO Finland
Body CT examination
1.5
6.8
235
1645
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.7
2222
20600
M47.9
ICD-10 Finland
Spondylosis, unspecified
1.9
6.7
83
448
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
6.7
321
2380
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.4
6.7
243
1716
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
2.0
6.7
64
316
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
6.7
722
5990
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
22.6
6.7
9
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.7
6.7
125
762
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.4
6.6
297
2177
C09CA06
ATC
candesartan; oral
1.3
6.6
644
5276
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
6.6
512
4076
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.5
6.6
38
151
Z13.6
ICD-10 Finland
Special screening examination for cardiovascular disorders
3.5
6.6
22
64
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
1.9
6.6
80
430
S83.4
ICD-10 Finland
Sprain and strain involving (fibular)(tibial) collateral ligament of knee
1.8
6.5
100
576
EDB00
NOMESCO Finland
Partial excision of mandible
8.7
6.5
13
15
L14
ICPC
Leg/thigh symptom/complaint
1.5
6.5
203
1390
C10AC01
ATC
colestyramine; oral
1.9
6.5
72
374
TQW40
NOMESCO Finland
Remowal of suture of skin
1.5
6.5
187
1260
ND1AI
NOMESCO Finland
Cone beam CT of wrist
2.8
6.5
30
106
M01AC01
ATC
piroxicam; systemic, rectal
1.4
6.5
325
2426
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.0
6.5
66
333
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.5
1164
10181
R03BA05
ATC
fluticasone; inhalant
1.3
6.5
512
4085
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.5
1228
10799
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
6.5
302
2229
M54.6
ICD-10 Finland
Pain in thoracic spine
1.5
6.5
209
1443
AA1ED
NOMESCO Finland
Trauma CT of head and neck
3.7
6.5
20
55
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.0
6.5
66
334
Q78.9
ICD-10 Finland
Osteochondrodysplasia, unspecified
70.0
6.4
7
*
JN4BD
NOMESCO Finland
Extensive body CT
1.4
6.4
242
1721
Z47.8
ICD-10 Finland
Other specified orthopaedic follow-up care
3.2
6.4
24
75
J02AC02
ATC
itraconazole; systemic
1.3
6.4
487
3866
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
2.2
6.4
53
248
S83.2
ICD-10 Finland
Tear of meniscus, current
1.5
6.4
198
1357
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
1.5
6.4
181
1218
D18.0
ICD-10 Finland
Haemangioma, any site
1.9
6.3
72
378
N05CF01
ATC
zopiclone; oral
1.2
6.3
852
7239
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.1
6.3
56
269
AA1AA
NOMESCO Finland
Head X-ray examination
3.1
6.3
25
81
M70.6
ICD-10 Finland
Trochanteric bursitis
1.4
6.3
328
2467
M02AA10
ATC
ketoprofen; topical
1.3
6.3
411
3198
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.5
6.3
185
1255
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.4
6.2
251
1806
M77.0
ICD-10 Finland
Medial epicondylitis
1.9
6.2
77
416
NGR99
NOMESCO Finland
Other operation for tumour of knee or lower leg
26.7
6.2
8
*
M09AX01
ATC
hyaluronic acid; parenteral
1.7
6.2
104
615
OAB91, ,
SPAT
1.5
6.2
191
1306
A02BA02
ATC
ranitidine; systemic
1.3
6.2
476
3783
R05
ICD-10 Finland
Cough
1.3
6.2
588
4800
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
2.6
6.2
35
138
SPAT1043
SPAT
Audiometry
1.4
6.2
231
1641
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
6.1
338
2563
EFA50
NOMESCO Finland
Excision of cyst of jaws
2.6
6.1
33
127
NA3BG, ,
SPAT
1.6
6.1
119
733
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.7
6.1
97
566
M23.8
ICD-10 Finland
Other internal derangements of knee
1.7
6.1
107
642
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.6
6.1
141
907
SPAT1260
SPAT
Consultation of another employee
1.3
6.1
460
3650
R52.2
ICD-10 Finland
Other chronic pain
1.7
6.1
101
597
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.4
6.1
297
2211
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.4
6.0
328
2481
R74
ICPC
Upper respiratory infection acute
1.2
6.0
999
8659
J35.0
ICD-10 Finland
Chronic tonsillitis
1.5
6.0
162
1077
EBB10
NOMESCO Finland
Insertion of dental implant
2.3
6.0
43
189
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2479
21457
1.51
26.80
4.5
4.0
10.12
10.95
mm/h
2.74
2311
20002
2471
21877
1.42
19.78
7.6
7.3
77.03
76.66
u/l
0.14
2342
20719
1609
13433
1.36
17.48
2.6
2.5
—
—
—
0
0
693
5015
1.47
17.27
1.3
1.3
8.64
9.83
u/ml
0.22
286
2040
1893
16231
1.35
17.16
4.4
4.7
6.49
6.62
mmol/l
2.00
1779
15117
2130
18610
1.36
17.00
4.5
4.1
2899.59
1619.55
e6/l
0.19
17
246
711
5289
1.43
15.09
1.4
1.3
25.89
29.63
iu/ml
0.24
226
1698
3151
29664
1.52
14.52
14.1
12.8
21.13
22.45
mg/l
1.38
2559
23153
1397
11686
1.32
13.90
4.5
4.8
36.18
36.05
g/l
0.39
1278
10933
465
3241
1.50
13.73
7.1
6.3
—
—
—
0
0
3158
29810
1.51
13.66
15.3
14.2
139.74
139.66
mmol/l
1.12
3081
29083
1429
12013
1.32
13.65
12.3
13.0
1.18
1.21
inr
0.80
396
3628
927
7324
1.36
13.53
2.5
2.5
1989.63
4240.29
umol/l
1.58
814
6510
862
6767
1.36
13.03
2.3
2.2
—
—
—
0
0
1559
13335
1.30
12.85
6.5
6.6
1.21
1.21
mmol/l
0.03
1305
11373
3161
29910
1.49
12.81
15.5
14.3
3.95
3.95
mmol/l
0.19
3075
29128
1663
14413
1.29
12.13
5.9
6.1
11.21
11.12
umol/l
0.07
1565
13705
1415
12045
1.29
11.77
5.7
6.0
1.21
1.21
mmol/l
0.02
1273
11055
1067
8759
1.31
11.65
2.8
2.5
60.39
68.01
u/l
0.34
970
8131
989
8052
1.32
11.42
2.2
2.1
211.07
224.58
u/l
0.12
941
7602
1635
14220
1.28
11.30
3.8
3.5
0.00
0.00
estimate
1.32
317
2593
2500
22968
1.29
10.87
4.2
4.0
14.66
14.63
pmol/l
0.24
2313
21143
1615
14089
1.27
10.66
5.0
4.7
0.00
0.00
estimate
0.50
327
2693
1189
10001
1.28
10.55
3.4
3.3
31.05
47.28
ng/l
1.21
746
6202
1613
14102
1.26
10.34
3.8
3.5
0.00
0.00
estimate
0.10
335
2806
191
1190
1.64
9.22
1.3
1.3
0.63
0.88
u/ml
0.30
12
101
1711
15201
1.24
9.06
6.1
6.1
0.19
0.19
e9/l
0.18
1521
13448
2880
27198
1.30
8.71
5.1
4.7
2.61
2.02
mu/l
0.31
2682
25260
1269
10959
1.24
8.56
4.0
3.6
—
—
—
0
0
434
3251
1.38
8.52
4.1
4.2
32.15
31.90
%
0.18
306
2302
1358
11827
1.24
8.45
2.4
2.2
77.39
75.67
nmol/l
1.21
1237
10817
904
7540
1.27
8.19
4.3
3.8
0.00
0.00
estimate
1.28
313
2610
1692
15135
1.22
8.01
6.0
5.9
1.96
1.95
e9/l
0.05
1514
13508
857
7137
1.26
7.81
3.5
3.9
92.65
92.26
%
0.18
834
6956
1865
16879
1.22
7.76
8.3
9.0
4.03
4.04
e9/l
0.08
1642
14821
121
707
1.74
7.48
1.4
1.4
—
—
—
0
0
830
6920
1.26
7.44
1.3
1.3
1.21
1.60
u/ml
0.45
225
1879
1068
9162
1.24
7.41
2.9
3.3
2.35
2.35
mmol/l
0.05
945
8191
1491
13278
1.21
7.07
6.2
6.1
0.68
0.68
%
0.05
1383
12442
306
2240
1.40
6.88
2.5
2.7
9.86
10.45
g/l
2.06
275
2053
1531
13715
1.20
6.70
6.2
6.1
2.90
2.84
%
0.53
1432
12874
1540
13804
1.20
6.70
6.6
6.4
8.48
8.45
%
0.16
1439
12990
1560
14071
1.19
6.16
6.1
5.9
56.30
56.72
%
0.77
1462
13263
88
501
1.78
6.03
2.5
3.6
341.32
862.04
u/ml
0.48
78
473
63
322
1.97
6.02
1.5
1.7
59.31
58.87
%
0.03
39
203
272
2004
1.39
5.91
2.6
2.7
67.33
66.68
g/l
0.83
249
1844
1574
14247
1.19
5.88
6.4
6.1
28.97
28.65
%
0.56
1478
13444
480
3850
1.29
5.82
2.5
2.4
108.58
124.64
ug/g
0.75
375
3108
105
639
1.66
5.68
1.5
1.7
14025.84
12672.89
e6/l
0.12
81
467
719
6061
1.23
5.68
1.6
1.4
2.18
2.34
g/l
2.03
458
3825
2935
28133
1.24
5.67
4.5
4.1
5.83
5.85
mmol/l
0.44
2705
25969
3406
33316
1.47
5.64
21.1
18.8
40.67
40.63
%
0.08
3243
31461
435
3461
1.29
5.62
5.3
6.1
1.04
1.04
mmol/l
0.13
414
3233
1211
10760
1.19
5.50
1.9
1.9
100.52
96.48
pmol/l
1.84
643
5682
794
6787
1.22
5.45
2.7
2.9
983.20
1170.92
ng/l
0.79
660
5705
2197
20529
1.18
5.45
3.5
3.0
44.82
45.22
u/l
0.09
2049
19384
3408
33372
1.45
5.26
21.0
18.6
4.54
4.54
e12/l
0.10
3332
32549
3409
33384
1.45
5.25
21.1
18.7
136.41
136.44
g/l
0.04
3371
32977
2890
27713
1.22
5.23
12.4
11.6
86.09
85.42
ml/min/173m2
0.96
2434
22857
3408
33375
1.45
5.22
21.0
18.7
6.66
6.68
e9/l
0.16
3333
32550
143
957
1.51
5.21
1.8
1.8
—
—
—
0
0
130
859
1.53
5.04
1.3
1.2
2.16
44.92
u/ml
—
5
53
743
6356
1.21
5.03
1.6
1.5
—
—
—
0
0
3404
33347
1.43
5.01
21.1
18.7
256.29
255.27
e9/l
0.42
3336
32597
673
5706
1.22
4.98
2.4
2.5
6.35
6.23
e6/l
0.07
590
5125
1454
13203
1.17
4.95
3.0
2.8
106.37
113.25
ug/l
0.75
1365
12342
95
593
1.62
4.72
1.5
1.4
—
—
—
0
0
234
1752
1.36
4.65
2.0
1.8
1.43
1.34
g/l
0.18
210
1618
349
2769
1.29
4.62
2.3
2.1
345.84
370.84
nmol/l
1.70
324
2544
2756
26397
1.19
4.60
5.6
5.2
38.82
39.18
mmol/mol
1.39
2567
24695
287
2222
1.32
4.56
2.3
2.5
70.95
70.68
ml/min/173m2
0.04
133
849
67
389
1.74
4.39
1.2
1.3
0.15
0.33
nmol/l
—
6
23
119
797
1.51
4.38
1.4
1.4
256.78
292.83
ug/g
0.98
58
441
177
1280
1.40
4.37
2.1
1.9
39.52
39.06
u/l
0.11
158
1154
119
798
1.51
4.35
1.3
1.2
7.47
7.74
u/ml
0.02
16
134
749
6503
1.19
4.26
1.8
1.7
1.02
1.07
mg/l
0.13
571
4874
55
304
1.82
4.26
2.7
3.2
2.24
24.45
nmol/l
0.66
49
296
2239
21147
1.16
4.23
3.3
3.2
—
—
—
0
0
116
783
1.50
4.13
1.3
1.2
29.79
2.99
u/ml
0.45
11
84
520
4377
1.22
4.10
3.5
3.5
0.83
0.82
mmol/l
0.59
491
4139
497
4176
1.22
3.99
1.8
1.8
—
—
—
0
0
353
2858
1.26
3.98
4.1
4.2
244.97
243.77
u/l
0.04
335
2710
594
5084
1.20
3.94
3.2
3.5
580.45
467.74
ng/l
0.20
398
3621
853
7535
1.17
3.93
3.0
3.0
0.44
0.39
e6/l
0.19
662
5690
3049
29582
1.21
3.89
4.7
4.5
2.80
2.83
mmol/l
0.94
2839
27673
69
422
1.65
3.79
1.8
1.4
5.41
3.87
ug/l
0.35
60
382
225
1732
1.32
3.77
1.4
1.4
25.78
27.35
iu/l
0.30
198
1489
248
1937
1.30
3.74
2.8
3.3
4.52
4.53
pmol/l
0.12
224
1744
319
2578
1.26
3.67
2.6
2.2
0.23
0.22
g/l
1.10
304
2411
46
253
1.83
3.66
1.4
1.5
38.08
33.26
%
0.39
32
153
651
5663
1.18
3.59
1.6
1.6
443.14
34520520.29
pmol/l
5.04
535
4803
3007
29183
1.19
3.57
4.4
4.1
4.69
4.73
mmol/l
1.42
2801
27454
919
8223
1.16
3.55
3.0
3.1
53.66
95.31
e6/l
0.92
705
6279
247
1944
1.29
3.53
1.3
1.3
32.63
50.93
au/ml
—
8
103
216
1670
1.31
3.52
1.1
1.0
—
—
—
0
0
942
8454
1.16
3.48
3.4
3.3
7.93
7.84
mmol/l
0.20
804
7270
1080
9791
1.15
3.46
3.4
3.2
32.22
34.23
u/l
0.42
1033
9316
28
132
2.13
3.45
1.5
1.8
1.99
2.02
umol/l
0.09
28
126
40
216
1.86
3.40
2.1
2.1
—
—
—
0
0
257
2044
1.28
3.39
1.3
1.3
245.81
208.59
u/ml
0.21
243
1897
675
5927
1.17
3.31
1.5
1.5
20.97
20.57
nmol/l
0.27
579
5138
2891
28009
1.17
3.30
3.9
3.7
1.27
1.30
mmol/l
1.80
2677
26068
867
7764
1.15
3.28
4.8
4.4
1.95
2.29
ug/l
1.52
802
7024
310
2534
1.24
3.25
3.6
4.1
33.75
20.46
ug/l
0.34
243
2027
2985
29005
1.18
3.23
4.3
4.1
1.46
1.46
mmol/l
0.05
2776
27157
776
6903
1.16
3.21
2.3
2.1
2.84
2.88
mg/l
0.20
674
5925
242
1928
1.27
3.17
3.2
3.9
72.00
83.31
ng/l
1.75
215
1707
91
621
1.48
3.16
1.3
1.2
6.92
3.49
u/ml
—
9
46
77
508
1.53
3.14
1.8
1.7
—
—
—
0
0
550
4770
1.18
3.14
2.7
2.9
2.44
2.44
mmol/l
0.48
477
4189
268
2166
1.26
3.12
3.9
3.7
1.22
1.23
mmol/l
0.36
231
1893
37
201
1.85
3.11
1.5
2.0
3.15
4.04
mg/l
1.20
37
192
457
3908
1.19
3.07
2.1
2.1
—
—
—
0
0
696
6167
1.16
3.03
4.2
3.8
1.02
1.02
kg/l
0.25
103
867
345
2876
1.22
3.02
1.7
1.7
—
—
—
0
0
3226
31595
1.22
3.01
11.0
9.7
27.39
26.91
u/l
0.68
3129
30654
259
2095
1.25
3.00
2.2
2.3
6.39
7.38
ug/l
0.40
223
1875
166
1269
1.32
2.98
1.6
1.6
313.26
297.25
mu/l
0.20
154
1147
341
2849
1.22
2.93
1.7
1.7
—
—
—
0
0
523
4546
1.18
2.91
1.7
1.7
1199.76
1170.10
nmol/l
0.31
396
3503
44
258
1.71
2.90
1.3
1.4
111929.15
85772.46
e6/l
0.13
26
178
12
38
3.17
2.84
1.0
1.0
0.06
1.99
u/ml
—
7
27
14
53
2.65
2.79
1.9
1.3
0.58
0.37
ug/l
—
9
36
384
3262
1.20
2.78
2.5
2.8
9.34
7.50
umol/l
0.60
328
2832
875
7925
1.14
2.77
3.7
3.9
5.58
8.73
mg/mmol
2.15
557
5071
268
2198
1.24
2.76
2.0
2.3
12.87
12.83
nmol/l
0.03
242
2002
259
2119
1.24
2.73
2.4
2.4
15.60
22.29
au/ml
0.93
18
184
522
4566
1.17
2.69
2.6
2.6
1.39
1.16
e6/l
0.32
299
2556
499
4355
1.17
2.64
2.2
2.1
—
—
—
0
0
468
4073
1.17
2.57
1.7
1.8
1.45
1.43
%
0.24
415
3636
272
2257
1.22
2.53
1.2
1.2
142.97
152.45
iu/ml
0.13
98
854
833
7566
1.13
2.50
3.2
3.3
308.12
354.05
mg/l
0.11
526
4848
1389
13019
1.11
2.38
9.5
9.0
0.00
0.00
e9/l
1.36
1139
10638
230
1890
1.23
2.37
1.6
1.7
—
—
—
0
0
41
251
1.64
2.36
1.2
1.3
—
—
—
0
0
465
4074
1.16
2.36
1.9
2.2
29.62
29.66
s
0.04
446
3949
77
544
1.42
2.32
1.4
1.4
0.32
0.37
nmol/l
0.26
63
427
25
133
1.89
2.31
1.1
1.1
382.39
188.98
iu/ml
0.40
25
133
24
127
1.90
2.25
1.5
1.4
3.00
4.38
%
—
5
26
48
310
1.56
2.24
1.6
2.3
13.82
22.65
mg/l
1.46
11
86
61
417
1.47
2.20
2.2
2.1
5.71
5.92
umol/l
0.07
35
300
125
965
1.31
2.18
1.9
1.6
132.50
352.35
titre
—
8
34
440
3864
1.16
2.17
2.3
2.4
2.42
2.37
g/l
1.13
410
3601
147
1160
1.28
2.17
1.5
1.5
—
—
—
0
0
31
181
1.72
2.15
1.6
1.4
4.96
7.38
u/l
1.43
26
153
89
655
1.37
2.14
1.3
1.2
61.19
41.94
u/ml
—
7
66
476
4213
1.15
2.11
2.2
2.4
14.65
13.75
umol/l
1.74
446
3951
10
37
2.71
2.07
1.7
1.4
—
—
—
0
0
80
584
1.38
2.04
6.0
8.1
104.70
105.38
mmol/l
0.72
70
524
2668
25956
1.11
2.00
15.8
15.2
15.00
14.81
%
0.43
2623
25494
477
4249
1.14
1.94
2.8
2.8
3.18
2.74
e6/l
0.42
260
2249
5
11
4.55
1.94
1.0
1.4
—
—
—
0
0
407
3587
1.15
1.93
2.3
2.5
25.29
23.49
%
1.44
341
3094
125
984
1.28
1.92
1.7
1.8
—
—
—
0
0
171
1397
1.24
1.91
8.3
11.4
—
—
—
0
0
21
113
1.86
1.91
2.3
2.4
—
—
—
0
0
31
188
1.65
1.90
1.3
1.3
—
—
—
0
0
102
785
1.31
1.86
4.2
3.8
1.38
1.45
mg/l
0.43
94
734
8
28
2.86
1.86
1.0
1.0
—
—
—
0
0
105
812
1.30
1.85
2.5
2.8
—
—
—
0
0
148
1195
1.25
1.85
1.9
1.5
17.77
15.11
u/ml
—
6
34
18
93
1.94
1.84
1.4
1.4
9.08
8.54
ug/l
0.15
18
93
122
964
1.27
1.83
1.9
1.7
1.16
1.18
g/l
0.38
112
913
26
152
1.72
1.83
1.6
1.5
11.50
13.62
u/l
0.93
26
145
129
1029
1.26
1.80
1.8
1.8
—
—
—
0
0
39
255
1.54
1.78
1.7
1.5
1.35
1.25
promille
0.15
29
203
678
6204
1.11
1.78
4.2
3.9
20.79
21.28
%
0.36
317
2764
123
977
1.27
1.78
1.4
1.4
10.17
9.75
u/l
0.13
105
811
78
582
1.35
1.77
2.2
2.3
131.04
130.92
g/l
0.01
57
425
63
455
1.39
1.75
1.0
1.1
2.12
5.29
u/ml
2.21
28
184
27
162
1.67
1.74
2.1
2.7
811.44
1038.36
u/ml
0.39
27
162
100
780
1.29
1.68
1.7
1.7
—
—
—
0
0
186
1557
1.21
1.67
2.6
3.1
27.48
46.31
u/ml
2.51
178
1502
171
1420
1.21
1.67
2.4
2.3
4379.86
4698.83
u/l
0.06
55
550
19
104
1.83
1.67
3.6
5.3
—
—
—
0
0
19
104
1.83
1.67
1.1
1.0
—
—
—
0
0
13
62
2.10
1.65
1.1
1.1
0.01
5.69
u/ml
—
8
45
32
204
1.57
1.65
1.1
1.2
—
—
—
0
0
117
935
1.26
1.63
1.7
1.8
40.31
38.96
nmol/l
0.24
111
909
13
63
2.07
1.59
1.0
1.1
98.31
92.06
%
0.48
13
63
14
70
2.00
1.59
3.5
3.2
178.31
169.22
ng/l
—
8
42
116
930
1.26
1.58
2.0
1.7
0.23
0.23
g/l
0.17
103
879
134
1095
1.23
1.55
1.9
2.0
—
—
—
0
0
186
1572
1.19
1.53
3.7
3.9
1.48
1.67
mmol/l
0.33
150
1169
95
747
1.28
1.53
1.4
1.3
7.33
8.94
iu/ml
—
6
14
6
21
2.86
1.50
1.7
1.1
—
—
—
0
0
108
865
1.26
1.50
1.1
1.1
0.81
4.21
u/ml
—
10
120
23
140
1.65
1.44
1.3
2.8
213.11
166.47
umol/l
—
9
76
47
338
1.40
1.39
1.5
1.5
—
—
—
0
0
86
678
1.28
1.38
2.0
1.9
195.81
204.69
pmol/l
0.33
81
640
67
511
1.32
1.38
1.6
1.9
4.97
5.19
mmol/24h
0.27
62
453
47
339
1.39
1.37
1.0
1.1
—
—
—
0
0
227
1973
1.16
1.37
2.5
2.8
180.48
175.53
ng/l
0.04
204
1780
77
600
1.29
1.36
1.5
2.2
0.89
0.83
nmol/l
0.28
66
508
192
1650
1.17
1.34
3.6
3.9
5.27
5.17
kpa
0.97
180
1578
19
113
1.69
1.31
1.1
1.2
—
—
—
0
0
572
5276
1.10
1.31
1.5
1.5
—
—
—
0
0
115
945
1.22
1.31
1.8
1.8
—
—
—
0
0
74
579
1.28
1.28
3.3
3.7
57.35
56.95
%
0.09
74
579
13
69
1.89
1.28
1.1
1.1
—
—
—
0
0
110
902
1.23
1.28
1.9
2.4
534.71
485.60
ug/l
0.08
98
840
31
210
1.48
1.27
2.4
2.7
444.85
574.03
e6/l
0.79
20
174
98
795
1.24
1.26
1.8
2.6
0.70
1.01
g/l
0.43
81
707
21
130
1.62
1.26
1.5
1.4
—
—
—
0
0
177
1520
1.17
1.26
1.5
1.5
—
—
—
0
0
37
261
1.42
1.24
1.5
1.9
18.97
20.26
ug/l
0.18
37
256
30
203
1.48
1.24
2.5
2.7
0.21
0.22
e9/l
0.08
20
174
17
100
1.70
1.23
1.9
1.4
61.19
79.81
nmol/24h
0.77
17
100
86
690
1.25
1.23
2.9
3.6
16.66
1.58
ratio
—
5
58
145
1228
1.19
1.22
1.8
1.9
—
—
—
0
0
125
1047
1.20
1.19
4.0
4.0
24.79
24.82
mmol/l
0.04
113
982
56
427
1.32
1.19
1.2
1.2
—
—
—
0
0
29
197
1.48
1.19
1.1
1.1
4.86
10.82
iu/ml
—
8
56
28
189
1.49
1.18
1.0
1.1
1.02
1.10
u/l
—
6
96
88
712
1.24
1.18
3.4
3.6
169.34
56.31
mg/l
0.39
73
580
12
212
0.56
1.18
7.6
17.9
1111.25
1492.73
nmol/l
0.87
12
207
30
206
1.46
1.17
1.1
1.0
—
—
—
0
0
33
231
1.43
1.17
1.3
1.3
5.57
0.99
u/ml
0.49
22
123
21
133
1.58
1.17
1.5
1.4
—
—
—
0
0
45
333
1.36
1.16
6.2
6.7
10.28
11.49
mg/l
1.23
40
309
33
232
1.43
1.15
1.1
1.3
1.73
2.02
mmol/l
1.48
33
217
120
1006
1.20
1.15
5.1
5.9
2.04
1.67
%
0.88
110
937
12
210
0.57
1.14
6.7
13.1
643.17
855.16
nmol/l
0.98
12
203
88
715
1.24
1.14
1.5
1.5
75.69
167.88
pmol/l
2.45
83
704
274
2449
1.13
1.14
8.1
9.0
122.15
123.18
g/l
0.37
265
2382
16
95
1.69
1.13
1.8
2.0
—
—
—
0
0
45
335
1.35
1.13
1.5
1.5
—
—
—
0
0
10
51
1.96
1.11
1.5
1.1
—
—
—
0
0
119
1001
1.20
1.10
5.2
5.9
0.91
0.91
%
0.07
109
935
87
710
1.23
1.09
3.4
3.6
34.26
63.02
mg/l
1.78
72
577
8
41
1.95
1.08
1.1
1.3
—
—
—
0
0
44
330
1.34
1.07
1.5
1.5
—
—
—
0
0
44
330
1.34
1.07
1.5
1.5
—
—
—
0
0
134
1144
1.18
1.06
1.3
1.3
229.30
219.88
miu/ml
0.11
64
558
40
296
1.36
1.06
1.0
1.0
—
—
—
0
0
17
105
1.62
1.06
1.5
1.4
—
—
—
0
0
17
105
1.62
1.06
1.5
1.4
—
—
—
0
0
7
33
2.12
1.05
1.1
1.2
—
—
—
0
0
67
534
1.26
1.05
1.2
1.3
—
—
—
0
0
67
534
1.26
1.05
1.2
1.3
—
—
—
0
0
324
2941
1.11
1.05
7.5
8.1
1.10
1.08
mmol/l
0.04
264
2312
35
254
1.38
1.04
2.4
2.5
—
—
—
0
0
110
925
1.20
1.04
1.5
2.4
3.51
3.62
g/l
0.40
96
852
24
162
1.48
1.04
1.5
1.4
33.86
21.72
u/ml
—
7
32
30
212
1.42
1.03
1.2
1.2
—
—
—
0
0
44
332
1.33
1.03
1.5
1.5
—
—
—
0
0
44
332
1.33
1.03
1.5
1.5
—
—
—
0
0
110
926
1.19
1.03
1.5
2.4
7.00
7.30
g/l
1.40
96
852
110
926
1.19
1.03
1.5
2.4
—
—
—
0
0
28
196
1.43
1.02
1.2
1.7
—
—
—
0
0
324
2949
1.11
1.00
7.6
8.1
5.12
5.10
kpa
0.17
305
2825
104
874
1.20
1.00
1.5
2.4
2.76
2.94
g/l
1.17
90
800
324
2950
1.11
1.00
7.5
8.1
12.73
12.59
kpa
0.18
305
2826
63
502
1.26
1.00
1.0
1.0
3.81
3.76
u/ml
0.01
30
234
68
547
1.25
0.99
3.0
2.5
16.74
16.53
%
0.16
37
277
107
903
1.19
0.98
3.0
3.6
479.05
1771.25
u/ml
0.59
92
777
11
61
1.81
0.98
1.3
1.1
—
—
—
0
0
30
215
1.40
0.97
1.2
1.3
—
—
—
0
0
21
140
1.50
0.97
1.4
1.2
28.71
11.54
u/l
1.02
21
128
85
703
1.21
0.97
1.1
1.1
2.00
2.50
u/ml
0.14
45
367
224
2002
1.13
0.96
1.9
1.9
—
—
—
0
0
109
924
1.19
0.96
1.5
1.3
—
—
—
0
0
29
207
1.40
0.96
1.4
1.7
—
—
—
0
0
72
586
1.23
0.96
1.0
1.1
1.73
1.71
u/ml
0.01
33
293
101
853
1.19
0.93
1.6
2.4
9.97
10.07
g/l
0.09
85
777
104
881
1.19
0.93
1.2
1.1
—
—
—
0
0
32
234
1.37
0.93
1.2
1.1
—
—
—
0
0
32
234
1.37
0.93
1.2
1.1
—
—
—
0
0
22
150
1.47
0.92
1.1
1.1
1385.91
1527.45
miu/ml
0.23
22
150
167
1471
1.14
0.91
1.6
1.6
—
—
—
0
0
32
235
1.36
0.91
1.2
1.1
—
—
—
0
0
488
4554
1.08
0.90
3.1
2.8
0.73
0.72
ug/l
0.05
313
2843
27
193
1.40
0.90
1.1
2.1
—
—
—
0
0
60
483
1.25
0.89
1.2
1.1
—
—
—
0
0
15
95
1.58
0.87
1.1
1.2
—
—
—
0
0
8
43
1.86
0.87
3.0
3.7
33.00
43.08
umol/l
—
8
34
33
246
1.34
0.87
4.1
2.4
—
—
—
0
0
84
704
1.20
0.86
1.3
1.3
—
—
—
0
0
152
1337
1.14
0.86
2.6
2.8
0.35
0.31
e6/l
0.07
145
1297
34
256
1.33
0.84
1.1
1.1
—
—
—
0
0
50
398
1.26
0.83
1.1
1.2
—
—
—
0
0
47
588
0.80
0.81
2.7
3.7
25.33
25.07
mg/l
0.01
22
365
31
232
1.34
0.81
1.2
1.2
—
—
—
0
0
31
232
1.34
0.81
1.2
1.2
—
—
—
0
0
8
47
1.70
0.80
1.4
1.0
—
—
—
0
0
113
980
1.16
0.79
2.0
2.1
0.84
1.65
ug/l
1.30
101
881
5
24
2.08
0.74
4.8
2.1
—
—
—
0
0
60
496
1.21
0.74
1.1
1.1
—
—
—
0
0
75
635
1.18
0.72
1.1
1.1
7.73
6.14
u/ml
0.30
38
335
10
60
1.67
0.72
1.5
1.3
—
—
—
0
0
222
2025
1.10
0.71
2.4
2.7
68.08
71.10
e9/l
0.68
168
1528
100
868
1.16
0.71
2.4
2.6
3.60
3.58
g/l
0.04
92
824
294
2718
1.09
0.71
2.4
2.4
32.69
57.00
u/l
0.78
254
2349
179
1617
1.11
0.70
6.8
7.4
24.80
24.52
mmol/l
0.57
170
1537
285
2635
1.09
0.69
7.7
8.6
96.05
95.82
%
0.23
273
2547
64
537
1.20
0.69
1.2
1.1
12.66
13.29
au/ml
—
9
38
84
722
1.17
0.69
1.6
2.4
38.94
38.04
g/l
0.68
70
648
5
27
1.85
0.68
1.0
1.1
29.02
1157.84
u/l
—
5
19
39
312
1.25
0.66
4.0
4.7
28.53
75.50
u/ml
—
9
93
51
421
1.21
0.65
1.0
1.0
0.49
0.33
u/ml
—
10
127
20
147
1.36
0.61
1.1
1.7
—
—
—
0
0
5
30
1.67
0.61
2.0
2.2
—
—
—
0
0
18
130
1.39
0.61
1.2
1.2
—
—
—
0
0
71
610
1.17
0.61
1.0
1.1
1.98
1.35
u/ml
0.24
31
262
270
2509
1.08
0.60
2.0
2.0
—
—
—
0
0
0
20
0.00
0.60
0.0
11.0
—
168.07
—
0
14
0
20
0.00
0.60
0.0
3.8
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
91
798
1.14
0.60
2.8
3.4
0.35
0.34
u/ml
0.13
54
455
16
114
1.41
0.58
1.5
2.3
0.91
1.44
ug/l
0.75
16
105
6
35
1.72
0.57
1.0
1.0
—
—
—
0
0
41
337
1.22
0.57
2.2
2.3
—
—
—
0
0
6
36
1.67
0.56
1.8
2.0
—
—
—
0
0
295
2761
1.07
0.56
2.4
2.7
1.72
1.78
%
0.57
259
2473
40
329
1.22
0.55
1.5
1.8
—
—
—
0
0
70
607
1.16
0.55
3.9
4.0
8.41
8.37
kpa
0.06
70
594
22
168
1.31
0.55
1.5
1.6
28.77
25.88
umol/l
0.16
22
160
8
125
0.64
0.54
2.1
2.2
127.25
149.90
nmol/l
—
8
106
27
213
1.27
0.54
1.1
1.5
—
—
—
0
0
45
377
1.20
0.53
1.3
1.2
—
—
—
0
0
6
39
1.54
0.53
1.0
2.1
—
—
—
0
0
77
675
1.14
0.53
1.3
1.5
319.01
1293.12
e6/l
1.13
68
542
77
675
1.14
0.53
1.2
1.4
6.65
27.24
e6/l
1.44
63
517
9
62
1.45
0.53
1.1
1.2
—
—
—
0
0
247
2306
1.08
0.52
6.3
7.7
8.19
8.93
mmol/l
1.18
233
2212
61
527
1.16
0.51
1.3
1.5
—
—
—
0
0
65
565
1.15
0.50
1.6
1.5
—
—
—
0
0
57
491
1.16
0.50
1.5
1.8
—
—
—
0
0
21
162
1.30
0.50
1.8
1.3
131.71
134.08
nmol/l
0.14
21
162
12
84
1.43
0.49
1.2
1.2
—
—
—
0
0
46
390
1.18
0.49
1.4
1.3
—
—
—
0
0
16
119
1.35
0.48
1.3
1.2
—
—
—
0
0
71
805
0.88
0.48
1.5
1.5
—
—
—
0
0
33
398
0.83
0.47
2.7
3.2
0.86
0.83
nmol/l
0.15
27
311
79
885
0.89
0.45
1.4
1.4
—
—
—
0
0
66
581
1.14
0.45
2.3
3.0
30.95
36.40
umol/l
1.35
61
533
88
790
1.12
0.44
1.6
1.9
4.83
4.63
iu/l
0.05
30
294
38
321
1.19
0.43
1.2
1.2
—
—
—
0
0
9
127
0.71
0.43
4.8
3.9
—
—
—
0
0
185
1725
1.08
0.43
1.4
1.4
—
—
—
0
0
57
500
1.14
0.42
1.1
1.1
16.89
1137.00
iu/ml
0.55
18
120
334
3179
1.06
0.41
1.8
1.7
—
—
—
0
0
80
718
1.12
0.41
1.3
1.2
—
—
—
0
0
67
595
1.13
0.41
4.7
5.9
986.20
699.00
iu/ml
—
10
82
80
889
0.90
0.41
1.4
1.4
—
—
—
0
0
43
498
0.86
0.41
1.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
3.4
—
—
—
0
0
80
888
0.90
0.40
1.4
1.4
—
—
—
0
0
30
358
0.84
0.40
1.1
1.1
99.83
96.29
%
0.35
30
340
80
887
0.90
0.40
1.4
1.4
—
—
—
0
0
290
2754
1.06
0.40
3.6
3.2
—
—
—
0
0
28
233
1.20
0.38
1.1
1.2
—
242.86
—
0
7
26
215
1.21
0.38
1.5
1.5
—
—
—
0
0
25
206
1.22
0.37
1.6
2.3
0.75
2.01
u/field
1.79
16
94
107
982
1.09
0.37
1.6
1.6
0.82
6.63
iu/ml
0.43
26
187
10
136
0.73
0.37
1.1
2.2
18.92
77.53
ug/l
—
10
122
87
956
0.91
0.37
1.4
1.5
—
—
—
0
0
19
152
1.25
0.37
1.2
1.7
—
—
—
0
0
19
152
1.25
0.37
1.2
1.7
—
—
—
0
0
10
72
1.39
0.36
1.2
1.1
—
—
—
0
0
155
1656
0.93
0.35
1.5
1.5
—
—
—
0
0
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
23
190
1.21
0.34
1.0
1.1
0.09
6.24
nmol/l
—
5
40
6
44
1.36
0.34
1.2
1.2
—
—
—
0
0
6
44
1.36
0.34
1.2
1.3
18.17
23.33
%
—
6
33
36
311
1.16
0.34
1.1
1.1
—
—
—
0
0
59
529
1.12
0.33
1.5
1.4
28.06
25.54
u/l
0.21
47
440
17
210
0.81
0.33
1.5
1.7
—
—
—
0
0
33
284
1.16
0.33
2.7
1.4
286.38
281.14
mosm/kgh2o
0.44
24
222
22
182
1.21
0.33
3.5
2.7
41.81
43.79
%
0.23
16
96
55
613
0.90
0.32
1.4
1.7
—
—
—
0
0
43
379
1.14
0.32
1.3
1.6
—
—
—
0
0
16
128
1.25
0.32
1.9
2.1
—
—
—
0
0
16
128
1.25
0.32
1.9
2.1
—
—
—
0
0
7
53
1.32
0.30
1.3
1.2
—
—
—
0
0
42
371
1.13
0.30
1.3
1.5
—
—
—
0
0
16
129
1.24
0.30
2.0
2.1
—
—
—
0
0
21
176
1.19
0.28
1.2
1.6
—
—
—
0
0
34
298
1.14
0.28
1.6
1.8
—
—
—
0
0
97
902
1.08
0.28
1.2
1.1
—
—
—
0
0
96
893
1.08
0.27
1.2
1.1
—
—
—
0
0
8
64
1.25
0.27
1.0
1.1
—
—
—
0
0
29
252
1.15
0.27
1.4
1.4
1530.70
2553.01
e6/l
0.88
20
178
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
20
168
1.19
0.27
1.1
1.1
—
—
—
0
0
57
625
0.91
0.26
1.5
1.5
—
—
—
0
0
72
664
1.09
0.26
1.7
1.7
—
—
—
0
0
198
1891
1.05
0.26
3.1
3.3
4.68
4.66
kpa
0.04
192
1828
102
1089
0.93
0.26
1.8
1.8
1.45
1.54
g/l
0.59
90
953
34
301
1.13
0.25
1.4
1.8
—
—
—
0
0
27
235
1.15
0.25
1.2
1.2
—
—
—
0
0
11
87
1.27
0.24
1.1
1.1
—
—
—
0
0
11
87
1.27
0.24
1.1
1.1
—
—
—
0
0
9
77
1.17
0.24
1.2
1.1
—
—
—
0
0
16
133
1.20
0.24
1.4
1.4
176.13
164.49
mmol/24h
0.23
16
133
29
328
0.88
0.23
1.8
1.5
—
—
—
0
0
29
328
0.88
0.23
1.8
1.5
—
—
—
0
0
5
41
1.22
0.22
1.0
1.4
50.52
115.52
ng/l
—
5
41
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
8.26
—
0
11
0
11
0.00
0.21
0.0
3.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
1.39
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
47
430
1.09
0.21
1.5
1.4
—
—
—
0
0
8
102
0.78
0.21
1.0
1.3
—
—
—
0
0
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
13
0.00
0.21
0.0
1.2
—
4947.00
—
0
7
0
13
0.00
0.21
0.0
1.6
—
21.67
—
0
6
22
192
1.15
0.20
1.1
1.3
—
—
—
0
0
11
134
0.82
0.20
1.1
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
5.0
—
412.71
—
0
14
16
187
0.85
0.20
1.3
1.1
—
—
—
0
0
25
221
1.13
0.20
1.5
1.4
35312.75
106928.73
e6/l
1.08
16
132
9
113
0.80
0.20
1.0
1.0
—
—
—
0
0
73
685
1.07
0.19
1.7
1.7
—
—
—
0
0
53
492
1.08
0.18
1.2
1.2
2.81
4.83
u/ml
1.49
27
212
24
213
1.13
0.18
1.7
1.5
77.25
77.50
umol/l
0.01
24
213
18
157
1.15
0.17
1.1
1.1
—
—
—
0
0
18
158
1.14
0.16
1.1
1.1
—
—
—
0
0
11
92
1.20
0.16
1.1
1.1
—
—
—
0
0
48
448
1.07
0.15
4.5
5.3
369.67
369.07
umol/l
0.01
42
394
18
159
1.13
0.15
1.9
2.0
—
—
—
0
0
18
159
1.13
0.15
1.9
2.0
—
—
—
0
0
44
471
0.93
0.14
1.1
1.1
—
—
—
0
0
67
635
1.06
0.14
2.1
2.5
73.22
120.55
ug/min
0.69
36
400
67
636
1.05
0.14
1.4
1.4
—
22.06
—
0
14
53
501
1.06
0.12
1.2
1.2
2.07
4.36
u/ml
1.60
14
167
74
707
1.05
0.12
1.7
1.7
—
—
—
0
0
18
200
0.90
0.12
1.1
1.2
—
—
—
0
0
768
7601
1.01
0.11
1.6
1.6
1.43
1.39
mmol/l
0.33
668
6472
46
485
0.95
0.10
1.9
1.7
—
—
—
0
0
46
485
0.95
0.10
1.9
1.7
—
—
—
0
0
23
212
1.09
0.10
1.4
1.4
4.82
6.47
mmol/l
1.64
23
197
15
166
0.90
0.09
1.7
1.4
5.33
5.77
mmol/l
0.95
15
160
5
46
1.09
0.09
1.0
2.0
—
—
—
0
0
5
46
1.09
0.09
1.4
1.1
37.40
41.80
mg/l
—
5
40
131
1276
1.03
0.09
1.4
1.7
4.35
4.34
mg/l
0.00
97
924
41
389
1.05
0.09
1.2
1.5
—
—
—
0
0
15
165
0.91
0.08
1.0
1.0
17.61
41.74
ng/l
—
9
100
6
58
1.03
0.08
1.2
1.5
—
—
—
0
0
28
263
1.07
0.08
1.8
1.7
—
—
—
0
0
28
263
1.07
0.08
1.8
1.7
—
—
—
0
0
28
263
1.07
0.08
1.8
1.7
—
—
—
0
0
5
60
0.83
0.08
1.0
1.3
—
—
—
0
0
113
1159
0.97
0.08
1.4
1.4
—
—
—
0
0
7
65
1.08
0.08
1.4
1.3
—
—
—
0
0
15
164
0.91
0.08
1.0
1.0
346.60
278.42
ng/l
—
10
104
77
792
0.97
0.07
4.2
4.2
3.82
3.88
mmol/l
0.67
77
786
9
88
1.02
0.07
1.1
1.1
—
—
—
0
0
34
325
1.05
0.06
1.0
1.1
—
—
—
0
0
12
109
1.10
0.06
1.3
1.1
—
—
—
0
0
15
162
0.93
0.06
1.0
1.0
761.30
730.43
ng/l
—
10
101
70
682
1.03
0.05
1.3
1.2
—
—
—
0
0
26
247
1.05
0.05
1.2
1.1
—
—
—
0
0
51
494
1.03
0.05
1.5
1.5
—
—
—
0
0
16
149
1.07
0.05
1.1
1.3
—
73.37
%
—
0
19
235
2326
1.01
0.04
3.5
4.0
5.93
5.86
kpa
0.49
229
2255
234
2318
1.01
0.04
3.5
4.0
1.83
1.97
mmol/l
0.30
200
1934
51
497
1.03
0.04
2.7
3.0
1.31
1.51
mmol/l
1.80
51
479
24
250
0.96
0.03
4.1
4.1
—
—
—
0
0
56
572
0.98
0.03
1.4
1.4
103.11
115.71
u/ml
0.50
19
112
10
92
1.09
0.03
1.1
1.1
—
—
—
0
0
20
192
1.04
0.02
2.4
1.7
—
—
—
0
0
21
216
0.97
0.00
1.3
1.3
1.52
1.57
g/l
0.22
21
216
26
254
1.02
0.00
1.4
1.4
—
—
—
0
0
20
198
1.01
0.00
1.1
1.1
1.04
1.04
ratio
—
7
78
64
642
1.00
0.00
1.3
1.2
256.05
268.20
u/ml
0.10
39
387
109
1092
1.00
0.00
1.5
1.4
—
—
—
0
0
49
485
1.01
0.00
1.8
1.6
—
—
—
0
0
12
121
0.99
0.00
1.8
1.8
—
—
—
0
0
28
279
1.00
0.00
1.4
1.6
—
—
—
0
0
47
466
1.01
0.00
2.8
3.1
6.77
7.36
mmol/l
1.36
47
452
10
97
1.03
0.00
2.7
3.3
—
—
—
0
0
10
103
0.97
0.00
1.0
1.1
—
—
—
0
0
13
127
1.02
0.00
1.5
1.7
—
—
—
0
0
13
127
1.02
0.00
1.5
1.7
—
—
—
0
0
19
193
0.98
0.00
1.9
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
0.00
1.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.20
—
0
5
5
55
0.91
0.00
1.4
2.9
1.22
1.20
mmol/l
—
5
55
9
97
0.93
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
25
250
1.00
-0.00
1.2
1.4
113.21
202.84
pmol/l
1.50
25
250
46
460
1.00
-0.00
1.0
1.1
1.42
2.65
u/ml
1.15
26
227
103
1030
1.00
-0.00
1.3
1.3
—
—
—
0
0
6
67
0.90
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.6
—
96.29
—
0
7
7
72
0.97
-0.00
1.3
2.2
13.40
16.64
umol/l
—
7
72
7
79
0.89
-0.00
1.3
2.8
—
—
—
0
0
7
79
0.89
-0.00
1.3
2.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.8
—
46.40
—
0
8
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BONE_CARTILAGE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_CARTILAGE | 1.057 [0.93, 1.21] | 0.407 |
| Birth year | 0.999 [0.99, 1.01] | 0.714 |
During the follow-up period (1.1.1998 — 31.12.2019), 530 out of 7903 females with CD2_BENIGN_BONE_CARTILAGE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BONE_CARTILAGE | 1.056 [0.93, 1.2] | 0.408 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 589 out of 7613 males with CD2_BENIGN_BONE_CARTILAGE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BONE_CARTILAGE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.093% | 0.165% |
| 5 | 0.603% | 1.185% |
| 10 | 1.661% | 2.905% |
| 15 | 3.341% | 5.841% |
| 20 | 6.078% | 9.778% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_CARTILAGE – Benign neoplasm of bone and articular cartilage
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data