Benign neoplasm: Vertebral column

CD2_BENIGN_VERTEB_COLUMN

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D16.6& Hospital discharge: ICD-9 — 2132 Hospital discharge: ICD-8 — 21301 Cause of death: ICD-10 — D16.6& Cause of death: ICD-9 — 2132 Cause of death: ICD-8 — 21301 2 out of 7 registries used, show all original rules.	94
4. Check minimum number of events None	94
5. Include endpoints None	94
6. Filter based on genotype QC (FinnGen only)	92

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D16
Name in latin: Neoplasma benignum columnae vertebralis

NAME	CD2_BENIGN_VERTEB_COLUMN
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D166
HD_ICD_9	2132
HD_ICD_8	21301
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D166
COD_ICD_9	2132
COD_ICD_8	21301
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Vertebral column based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	92	48	44
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	53.57	50.77	56.64

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
94: Matched controls
940

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D16.6

ICD-10 Finland

Benign neoplasm: Vertebral column

+∞

95.9

21301

ICD-8 Finland

Benign neoplasm of bone and cartilage, Columnae vertebralis (sacro et coccyge exclusis)

+∞

13.9

D48.0

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage

41.0

9.2

2132A

ICD-9 Finland

Benign neoplasm of bone and articular cartilage, Vertebral column, excluding sacrum and coccyx

+∞

7.4

NA2AD

NOMESCO Finland

Thoracic spine CT examination

74.7

6.5

NK6CT

NOMESCO Finland

Bone biopsy with CT guidance

74.7

6.5

ABB00

NOMESCO Finland

Excision of lesion of spinal canal

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40761535) Cells panel - Urine sediment

3.12

3.63

5.8

3.5

—

(3044889) 12 lead EKG panel

525

2.18

2.82

4.0

3.7

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

2.69

2.70

2.8

3.5

60.00

68.97

ml/min/173m2

—

(40768797) Stomach Pathology biopsy report

112

2.26

2.57

1.4

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.38

2.48

6.9

8.4

—

(40760888) Immunoglobulin light chains.free panel - Serum

5.26

2.44

2.3

2.8

—

(3048689) Calprotectin [Mass/mass] in Stool

2.28

2.36

1.2

2.3

168.06

102.59

ug/g

0.31

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

4.85

2.31

1.5

1.3

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

3.10

2.14

1.4

21.06

25.19

iu/l

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.18

2.07

1.4

1.6

—

(3021601) Nitrite [Presence] in Urine by Test strip

374

1.79

2.04

6.8

5.5

0.00

estimate

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.16

2.02

1.4

1.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

178

1.82

1.76

6.6

3.5

—

(3000494) Fungus identified in Specimen by Culture

2.01

1.72

2.3

1.7

—

(3035350) Ketones [Presence] in Urine by Test strip

380

1.67

1.65

5.8

3.9

0.00

estimate

-0.00

(40768804) Tissue Pathology biopsy report

305

1.68

1.65

2.5

2.0

—

(3009261) Glucose [Presence] in Urine by Test strip

382

1.66

1.60

5.7

3.9

0.00

estimate

-0.00

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

354

1.66

1.59

5.7

9.0

1.20

1.22

mmol/l

0.95

299

(3029937) Albumin [Presence] in Urine by Test strip

210

1.71

1.55

7.1

3.8

0.00

estimate

-0.00

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

2.58

1.53

4.1

4.8

46.01

51.65

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

292

1.64

1.51

6.5

4.1

—

(3020891) Body temperature

2.62

1.48

5.9

4.8

—

(3005322) IgE [Units/volume] in Serum or Plasma

2.44

1.48

1.0

1.3

196.07

114.92

u/ml

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.71

1.39

1.3

1.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

3.05

1.37

1.6

1.4

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.60

1.32

1.3

1.4

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

2.87

1.30

1.4

1.3

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

151

1.69

1.27

4.7

2.8

0.80

0.82

ug/l

0.05

104

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.58

1.16

1.6

1.3

—

(3015736) pH of Urine

308

1.52

1.14

6.0

3.6

—

5.74

—

(3037467) Urinalysis macro (dipstick) panel - Urine

516

1.52

1.10

4.8

4.3

—

(40758558) Short blood count panel - Blood

184

1.57

1.07

10.3

6.6

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.34

1.04

1.4

1.5

—

(3021589) Normoblasts [#/volume] in Blood

313

1.48

1.04

10.4

9.9

0.00

e9/l

0.49

247

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.99

0.0

2.1

—

(3022217) INR in Platelet poor plasma by Coagulation assay

364

1.45

0.98

11.9

9.9

1.33

1.20

inr

—

106

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

198

1.51

0.95

6.1

4.7

20.54

20.89

0.03

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

763

1.75

0.93

5.2

5.0

2.77

2.74

mmol/l

0.10

700

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

129

1.59

0.92

2.5

3.0

2.25

0.97

e6/l

0.37

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

741

1.67

0.91

4.4

4.5

1.46

mmol/l

0.00

676

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.99

0.91

2.0

1.5

—

(3001019) Free T4 and TSH panel - Serum or Plasma

2.14

0.91

1.7

—

(4200892) Spirometry reversibility

1.81

0.85

1.8

1.4

—

(40761511) CBC panel - Blood by Automated count

805

1.80

0.81

15.3

12.9

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.80

0.0

4.2

—

27.64

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.79

0.0

1.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

261

1.41

0.78

3.8

3.3

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.24

0.77

1.6

2.3

—

(3030467) Casts [#/volume] in Urine by Automated count

207

1.43

0.75

2.7

3.3

0.20

0.32

e6/l

0.42

150

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.81

0.73

4.9

25.61

24.76

mmol/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

128

1.50

0.72

1.6

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.61

0.72

2.2

1.6

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.76

0.71

4.6

2.8

0.66

0.69

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.72

0.70

4.6

2.8

0.93

1.34

—

(36304419) Bacteria [Presence] in Urine

204

1.38

0.63

2.6

3.1

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.62

0.62

1.8

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

289

1.34

0.62

2.0

99.20

96.93

pmol/l

0.13

141

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

715

1.43

0.60

4.4

4.2

1.14

1.28

mmol/l

1.29

653

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.59

0.0

1.1

—

(3020779) Urea [Moles/volume] in Serum or Plasma

1.53

0.59

7.1

11.4

8.34

9.63

mmol/l

—

(3024354) Oxygen [Partial pressure] in Venous blood

1.58

0.57

4.8

3.6

3.88

4.49

kpa

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.50

0.56

7.2

7.1

103.92

103.89

mmol/l

0.01

(3007164) IgA [Mass/volume] in Serum or Plasma

153

1.39

0.56

1.6

1.4

2.35

2.60

g/l

0.21

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.55

0.56

3.1

2.7

0.19

0.22

g/l

0.60

(3000991) Gas panel - Venous blood

1.53

0.56

10.4

9.1

—

(3026008) Bacteria identified in Urine by Culture

227

1.33

0.56

5.2

3.2

—

(40761536) Microorganisms panel - Urine sediment

1.50

0.55

5.3

4.1

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

172

1.36

0.55

1.2

1.3

0.90

0.93

u/ml

—

(3000330) Specific gravity of Urine by Test strip

1.53

0.52

4.5

4.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

452

1.28

0.52

10.1

9.7

4.43

4.10

e9/l

0.42

392

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

102

1.44

0.51

1.6

1.5

—

(3019060) Gas panel - Arterial blood

1.60

0.50

3.4

15.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

346

1.27

0.49

3.2

2.9

—

(3023368) Bacteria identified in Blood by Culture

197

1.29

0.43

4.1

4.2

—

(3002256) Pathology report gross observation

1.42

0.42

1.1

1.3

—

(3024928) Oxygen saturation in Venous blood

0.00

0.41

0.0

4.2

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

2.8

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.40

0.0

3.5

—

3.99

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.40

0.0

1.1

—

3.94

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.45

0.40

6.4

24.5

—

(3031040) Bacteria [#/volume] in Urine by Automated count

502

1.23

0.40

6.0

4.3

—

4303.15

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.36

0.39

2.4

2.3

3.17

4.88

ug/l

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.44

0.38

7.2

5.2

6.28

5.67

kpa

—

(3002032) Base excess in Venous blood by calculation

1.44

0.38

7.2

5.1

2.71

1.82

mmol/l

—

(4035726) Immunohistochemistry procedure

1.39

0.34

1.6

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.32

0.33

6.8

5.3

27.25

25.11

mmol/l

—

(3013115) Eosinophils [#/volume] in Blood

398

1.20

0.33

6.6

5.9

0.16

0.18

e9/l

0.83

358

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

714

1.25

0.32

13.1

84.60

81.82

ml/min/173m2

0.49

577

(40760892) CBC W Ordered Manual Differential panel - Blood

360

1.19

0.31

8.3

6.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

206

1.22

0.30

3.9

—

(3002582) Erythrocytes [#/volume] in Urine

235

1.21

0.30

2.5

3.3

82.15

23.61

e6/l

0.36

176

(3002385) Erythrocyte distribution width [Ratio]

664

1.21

0.29

19.3

16.5

14.01

14.95

1.32

654

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.35

0.29

1.8

2.1

365.70

389.41

nmol/l

—

(3042936) Bacteria identified in Isolate by Culture

113

1.28

0.28

1.9

2.4

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

739

1.23

0.27

4.5

4.6

5.72

5.94

mmol/l

0.86

674

(3018095) Leukocytes [#/volume] in Urine

267

1.18

0.26

3.2

3.9

12.94

58.20

e6/l

1.68

189

(3019198) Lymphocytes [#/volume] in Blood

395

1.16

0.25

6.6

5.8

1.82

1.94

e9/l

0.28

357

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.73

0.23

1.3

2.2

1.27

1.33

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

774

1.23

0.23

16.1

14.2

18.16

21.77

mg/l

0.63

605

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.1

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.21

0.0

1.4

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.9

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.21

0.0

1.1

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.5

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.6

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.5

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3000475) Leukocytes [#/volume] in Synovial fluid

0.00

0.21

0.0

1.5

—

10885.86

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.5

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.0

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.20

0.0

1.3

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.20

0.0

2.7

—

56.43

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.20

0.0

1.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

132

0.81

0.19

1.8

1.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

314

1.13

0.17

4.0

45.05

38.28

ng/l

0.11

214

(3001604) Monocytes [#/volume] in Blood

384

1.12

0.17

6.7

5.7

0.51

0.58

e9/l

1.78

339

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.79

0.15

3.9

3.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

122

1.17

0.15

2.6

3.2

0.83

2.87

e6/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.19

0.14

3.4

1.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

220

1.12

0.13

3.4

3.9

5.11

8.49

mg/mmol

0.51

146

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

163

1.13

0.12

2.9

1.7

7.80

1.35

mg/l

0.54

130

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.14

0.10

1.0

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.10

0.09

1.5

1.6

—

(3012516) Albumin [Mass/volume] in Urine

205

1.10

0.09

3.0

3.4

25.19

374.29

mg/l

0.56

139

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.06

0.08

1.3

1.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.78

0.08

1.8

1.9

—

(36660697) Celiac disease serology panel - Serum

1.08

0.08

1.1

1.2

—

(3006315) Basophils [#/volume] in Blood

384

1.07

0.08

6.9

5.7

0.04

e9/l

0.19

339

(1761868) Lipid panel - Serum or Plasma

285

0.93

0.08

3.3

3.0

—

(3000492) Spirometry study

0.80

0.08

1.5

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

108

1.13

0.07

1.5

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.87

0.07

1.7

2.1

—

(3022145) Colonoscopy Study observation

1.08

0.07

1.4

1.3

—

(21494755) Public health laboratory ask at order entry panel

1.05

0.07

1.2

1.3

—

(3003694) ABO and Rh group [Type] in Blood

192

0.92

0.06

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

228

1.07

0.05

3.7

2.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

140

1.08

0.05

1.4

1.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

510

0.96

0.03

3.1

3.0

—

(3013512) EKG study

199

0.94

0.03

4.5

4.2

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

611

1.04

0.03

8.2

7.8

72.18

77.33

u/l

0.54

566

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.08

0.02

1.5

1.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

172

0.99

0.00

3.8

2.7

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

126

1.04

0.00

8.8

3.9

0.82

mmol/l

0.10

118

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.97

-0.00

1.4

1.9

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.6

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.2

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.4

—

0.64

—

(3005033) Fetal Nuchal fold Thickness US

0.00

-0.00

0.0

1.6

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.3

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.0

—

6.23

—

(3009876) Amylase isoenzyme 3 panel - Serum or Plasma

0.00

-0.00

0.0

1.2

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.4

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

11.7

—

10.27

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.6

—

100.56

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.0

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.7

—

38.02

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

-0.00

0.0

1.5

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

270.38

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

0.32

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3025941) Bacteria identified in Stool by Culture

1.00

-0.00

1.0

1.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.00

-0.00

1.6

1.3

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3014271) Vancomycin [Susceptibility]

0.00

-0.00

0.0

2.0

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

2.5

—

11.41

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

128.16

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

0.86

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.0

—

1214.17

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.2

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.2

—

35.94

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

2.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.8

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

7.3

—

728.67

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.6

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.6

—

(3020013) Alkaline phosphatase.intestinal [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

13.00

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.6

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.7

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_VERTEB_COLUMN – Benign neoplasm: Vertebral column

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm: Vertebral column

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Benign neoplasm: Vertebral column (CD2_BENIGN_VERTEB_COLUMN)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints