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Benign neoplasm: Pelvic bones, sacrum and coccyx

DOID Endpoint Browser PheWeb

CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D16.8&
  • Hospital discharge: ICD-9 — 2136
  • Hospital discharge: ICD-8 — 21305
  • Cause of death: ICD-10 — D16.8&
  • Cause of death: ICD-9 — 2136
  • Cause of death: ICD-8 — 21305

2 out of 7 registries used, show all original rules.

158

4. Check minimum number of events

None

158

5. Include endpoints

None

158

6. Filter based on genotype QC (FinnGen only)

154

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum ossis coxae, ossis sacri sive ossis coccygis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 995 538 448
Only index persons 868 483 385
Unadjusted period prevalence (%)
Whole population 0.01 0.02 0.01
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 40.90 43.81 37.09
Only index persons 39.57 42.49 35.90

-FinnGen-

Key figures

All Female Male
Number of individuals 154 95 59
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 46.22 44.45 49.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
158
Matched controls
1580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
+∞
161.4
126
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
63.7
27.4
31
6
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
84.3
25.7
28
*
21305
ICD-8 Finland
Benign neoplasm of bone and cartilage, Pelvis, sacri, coccygis
+∞
20.2
19
*
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
+∞
20.2
19
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
7.0
20.0
35
62
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
26.6
17.0
23
10
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
100.9
16.9
18
*
2136A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Pelvic bones, sacrum and coccyx
+∞
14.8
14
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
10.3
10.9
21
23
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
12.5
10.9
19
17
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
39.1
9.1
11
*
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
+∞
8.4
8
*
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
23.5
8.1
11
5
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
47.4
7.8
9
*
9102
FHL
Trepanation or removal of the local bone process
47.4
7.8
9
*
NER50
NOMESCO Finland
Other operation for tumour of pelvis
+∞
7.3
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
7.0
71
393
M16.1
ICD-10 Finland
Other primary coxarthrosis
3.4
6.8
27
91
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.4
6.6
26
87
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
+∞
6.3
6
*
9101
FHL
Bone biopsy
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
107
758
2.28
5.48
7.4
9.6
3.92
4.09
e9/l
0.41
98
656
87
582
2.10
4.97
6.5
6.4
1.22
1.22
mmol/l
0.15
75
499
23
88
2.89
4.64
6.1
4.2
—
—
—
0
0
125
985
2.29
4.38
4.0
3.9
15.06
14.71
pmol/l
1.02
116
896
122
953
2.23
4.35
4.6
3.9
8.79
10.47
mm/h
1.32
115
880
75
493
1.99
4.32
4.4
3.4
6.40
5.80
ph
—
5
47
19
70
2.95
4.09
1.4
2.7
—
—
—
0
0
92
659
1.95
4.04
5.7
5.3
2.01
1.98
e9/l
0.06
81
593
78
532
1.92
3.93
6.1
5.2
1.22
1.22
mmol/l
0.17
73
495
85
608
1.86
3.60
4.8
3.5
0.00
0.01
estimate
0.50
15
135
88
639
1.85
3.53
5.9
5.3
0.04
0.04
e9/l
0.54
77
558
60
387
1.89
3.50
2.8
2.6
57.11
58.50
u/l
0.11
55
357
9
18
5.23
3.42
1.0
5.1
—
—
—
0
0
68
461
1.83
3.36
3.8
3.5
18.12
29.91
ng/l
1.33
48
296
23
105
2.39
3.28
3.9
4.1
—
—
—
0
0
87
639
1.80
3.28
5.9
5.3
0.56
0.56
e9/l
0.06
77
559
110
869
1.88
3.25
5.1
4.0
—
—
—
0
0
71
492
1.80
3.24
2.2
2.0
—
—
—
0
0
139
1193
2.37
3.22
5.1
4.6
1.73
1.89
mu/l
1.21
131
1095
89
662
1.79
3.18
5.9
5.7
0.22
0.18
e9/l
0.71
79
591
95
724
1.78
3.09
4.7
4.2
6.56
6.50
mmol/l
0.08
89
667
46
282
1.89
3.08
1.7
2.0
2.95
2.98
mg/l
0.04
38
243
84
620
1.76
3.04
4.8
3.6
0.00
0.00
estimate
-0.00
13
123
83
611
1.76
3.02
7.8
5.8
—
—
—
0
0
83
612
1.75
3.00
5.9
4.9
0.00
0.00
estimate
-0.00
15
130
55
366
1.77
2.80
3.7
2.9
—
—
—
0
0
23
116
2.15
2.62
1.9
2.0
444.65
376.97
nmol/l
0.98
23
107
145
1299
2.41
2.49
18.1
13.8
139.91
139.74
mmol/l
0.43
140
1267
87
675
1.64
2.42
6.4
6.0
9.40
11.20
umol/l
1.64
82
639
71
524
1.64
2.41
17.8
12.3
1.15
1.23
inr
0.37
19
170
48
320
1.72
2.38
6.0
7.9
—
—
—
0
0
145
1304
2.36
2.38
18.3
13.9
3.99
3.95
mmol/l
0.76
140
1270
28
159
1.92
2.33
2.1
2.0
—
—
—
0
0
49
333
1.68
2.26
4.5
3.7
—
—
—
0
0
12
48
2.62
2.24
2.1
2.6
71.00
6299.53
u/l
—
7
15
6
14
4.41
2.17
1.2
1.1
—
—
—
0
0
19
96
2.11
2.16
2.9
1.9
9.27
10.02
g/l
0.46
14
87
63
466
1.59
2.05
2.0
1.8
104.50
96.96
pmol/l
0.53
35
239
10
38
2.74
2.04
1.2
1.4
296.80
321.20
ug/g
—
5
22
45
307
1.65
2.02
2.8
2.4
292.85
5638.50
umol/l
1.24
40
267
54
386
1.61
2.02
2.4
2.1
—
—
—
0
0
40
266
1.67
1.98
5.9
3.5
—
—
—
0
0
75
582
1.55
1.96
5.9
5.1
0.75
0.65
%
1.14
70
544
145
1324
2.16
1.94
16.3
12.5
18.44
22.19
mg/l
0.90
121
1024
56
410
1.57
1.87
3.8
3.4
2.36
2.36
mmol/l
0.02
50
366
77
606
1.53
1.86
6.3
5.4
8.72
8.30
%
0.59
72
571
5
12
4.26
1.83
1.2
3.8
—
—
—
0
0
6
18
3.42
1.76
1.0
1.4
—
—
—
0
0
76
603
1.50
1.73
6.1
5.1
3.20
2.83
%
0.64
71
566
5
13
3.93
1.73
1.2
1.2
—
—
—
0
0
5
13
3.93
1.73
1.2
1.2
—
—
—
0
0
42
293
1.59
1.71
4.6
4.3
—
—
—
0
0
46
330
1.56
1.66
6.4
3.7
0.00
0.00
estimate
-0.00
14
129
74
588
1.49
1.66
10.6
8.8
0.00
0.00
e9/l
0.25
61
473
23
140
1.75
1.55
2.0
1.5
—
—
—
0
0
16
87
1.93
1.52
1.4
1.4
—
—
—
0
0
9
38
2.45
1.48
1.6
1.6
—
—
—
0
0
70
560
1.45
1.47
3.0
2.7
151.00
104.98
ug/l
0.48
65
517
34
234
1.58
1.46
1.4
1.3
24.02
29.37
iu/ml
—
8
83
12
60
2.08
1.42
3.2
2.1
—
—
—
0
0
48
360
1.48
1.39
3.0
3.2
—
—
—
0
0
31
212
1.58
1.37
1.6
1.6
1293.60
1201.58
nmol/l
0.23
25
153
20
123
1.72
1.32
1.6
2.0
—
—
—
0
0
6
24
2.56
1.31
1.2
2.5
—
—
—
0
0
45
338
1.46
1.29
1.4
1.2
0.62
1.11
u/ml
0.90
16
94
9
44
2.11
1.29
4.2
3.9
—
—
—
0
0
147
1381
1.93
1.28
16.8
11.6
—
—
—
0
0
132
1210
1.55
1.23
4.2
3.8
1.29
1.25
mmol/l
0.33
124
1126
146
1372
1.84
1.22
19.7
14.3
73.74
76.12
umol/l
0.63
146
1372
39
293
1.44
1.11
1.6
1.7
3.18
0.89
mg/l
0.41
27
223
127
1163
1.47
1.11
15.7
15.5
15.23
14.63
%
0.45
120
1149
22
146
1.59
1.10
1.3
1.2
—
—
—
0
0
11
59
1.93
1.10
1.0
1.3
—
—
—
0
0
5
21
2.42
1.10
1.0
1.5
—
—
—
0
0
5
21
2.42
1.10
1.2
1.1
—
—
—
0
0
47
367
1.40
1.08
4.5
4.1
7.40
7.40
ph
0.05
11
71
17
106
1.68
1.08
1.4
1.4
—
—
—
0
0
12
67
1.86
1.08
1.0
1.1
—
—
—
0
0
12
67
1.86
1.08
1.4
1.7
—
—
—
0
0
135
1259
1.50
0.98
4.6
4.2
1.43
1.48
mmol/l
0.55
129
1181
137
1282
1.52
0.97
5.2
4.6
2.51
2.78
mmol/l
3.26
131
1200
41
319
1.39
0.96
4.9
3.7
1.79
11.17
mg/mmol
2.04
30
200
39
302
1.39
0.94
4.2
3.1
17.27
79.27
mg/l
1.49
28
189
6
28
2.19
0.92
3.2
2.9
—
—
—
0
0
135
1265
1.46
0.89
4.8
4.2
4.34
4.68
mmol/l
4.31
129
1195
6
30
2.04
0.88
1.5
1.4
1.00
34.77
e6/l
—
6
22
6
30
2.04
0.88
1.5
1.3
11.33
2.62
e6/l
—
6
21
97
867
1.31
0.86
4.1
3.6
—
—
—
0
0
15
97
1.60
0.85
1.3
1.5
—
—
—
0
0
8
46
1.78
0.84
3.0
3.3
—
—
—
0
0
38
300
1.35
0.81
1.8
1.3
1.82
2.36
g/l
2.38
27
174
6
33
1.85
0.80
4.5
2.9
9.70
8.21
kpa
—
6
33
6
33
1.85
0.80
4.5
2.9
5.08
5.00
kpa
—
6
33
14
91
1.59
0.78
6.6
6.2
—
—
—
0
0
9
55
1.67
0.75
5.0
3.9
25.21
24.56
mmol/l
—
9
55
7
40
1.78
0.72
9.6
12.2
—
—
—
0
0
29
224
1.36
0.71
1.3
1.3
27.32
6.23
u/ml
0.64
17
89
7
42
1.70
0.69
2.4
1.4
12.91
6.38
u/l
—
7
35
15
103
1.50
0.68
1.3
1.3
—
—
—
0
0
13
87
1.54
0.65
1.5
1.2
—
—
—
0
0
24
184
1.36
0.62
2.8
2.7
0.59
0.76
ug/l
0.89
15
101
5
30
1.69
0.62
1.0
1.1
—
—
—
0
0
5
30
1.69
0.62
1.0
1.1
—
—
—
0
0
0
20
0.00
0.61
0.0
3.6
—
—
—
0
0
59
513
1.24
0.60
3.0
2.7
—
—
—
0
0
52
446
1.25
0.60
4.5
3.7
15.00
55.14
e6/l
2.14
38
304
41
342
1.27
0.60
3.0
2.8
—
—
—
0
0
0
22
0.00
0.60
0.0
2.1
—
—
—
0
0
38
315
1.27
0.58
2.2
2.0
—
—
—
0
0
6
37
1.65
0.56
1.2
1.3
0.22
0.23
g/l
—
6
37
23
179
1.33
0.55
1.2
1.4
336.00
374.29
titre
—
5
42
6
39
1.56
0.53
1.2
1.3
1.05
1.18
g/l
—
6
39
10
67
1.53
0.51
8.9
4.6
23.82
24.74
mmol/l
—
10
67
151
1472
1.58
0.50
25.5
18.5
40.51
40.64
%
0.12
145
1397
5
82
0.60
0.47
2.4
2.3
—
—
—
0
0
10
69
1.48
0.45
4.3
4.6
—
—
—
0
0
21
167
1.30
0.44
1.3
1.5
—
—
—
0
0
7
51
1.39
0.44
1.1
1.3
—
—
—
0
0
7
51
1.39
0.44
4.7
2.5
0.74
0.71
%
—
7
51
5
31
1.63
0.43
1.2
1.0
0.90
0.97
nmol/l
—
5
26
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
2.4
—
59.83
—
0
16
22
179
1.27
0.40
1.8
1.6
—
—
—
0
0
44
389
1.18
0.37
1.5
1.5
—
—
—
0
0
29
247
1.21
0.36
1.5
1.7
—
—
—
0
0
144
1403
1.30
0.35
12.4
9.6
25.86
26.74
u/l
0.34
139
1361
16
127
1.29
0.35
1.7
1.4
—
—
—
0
0
21
174
1.24
0.33
1.7
1.7
—
—
—
0
0
13
101
1.31
0.33
3.8
3.9
5.99
5.80
kpa
0.27
13
101
39
348
1.16
0.30
3.3
2.9
2.05
0.36
e6/l
0.49
31
252
7
57
1.24
0.29
1.1
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
1.53
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
14
117
1.22
0.21
7.8
6.8
4.84
5.03
kpa
0.53
14
112
0
12
0.00
0.21
0.0
1.3
—
0.92
—
0
12
0
12
0.00
0.21
0.0
17.3
—
1009.83
—
0
12
0
12
0.00
0.21
0.0
28.3
—
1959.67
—
0
12
10
80
1.27
0.21
2.2
2.9
76.00
67.64
e9/l
—
10
60
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
21
186
1.15
0.18
4.0
3.1
0.32
2.91
e6/l
2.43
13
91
120
1171
1.10
0.17
7.0
5.3
40.80
39.35
mmol/mol
0.86
112
1103
8
69
1.17
0.17
1.3
1.6
—
—
—
0
0
8
69
1.17
0.17
1.4
1.7
—
—
—
0
0
8
69
1.17
0.17
1.4
1.6
—
—
—
0
0
8
69
1.17
0.17
1.4
1.6
—
—
—
0
0
15
170
0.87
0.14
1.1
1.4
—
—
—
0
0
5
44
1.14
0.10
1.4
1.5
—
—
—
0
0
5
44
1.14
0.10
1.4
1.4
—
—
—
0
0
5
44
1.14
0.10
1.4
1.4
—
—
—
0
0
5
47
1.07
0.09
1.8
2.6
—
—
—
0
0
6
54
1.12
0.09
1.7
1.2
—
—
—
0
0
6
54
1.12
0.09
1.8
2.2
1.31
1.61
g/l
—
6
48
6
55
1.09
0.09
5.3
4.3
—
—
—
0
0
6
58
1.04
0.08
1.3
2.2
—
—
—
0
0
7
65
1.08
0.08
1.3
1.6
—
—
—
0
0
10
112
0.89
0.07
1.2
1.1
—
—
—
0
0
9
83
1.09
0.07
5.0
3.1
3.82
4.62
kpa
—
9
83
8
91
0.87
0.07
1.0
1.2
—
—
—
0
0
37
383
0.96
0.05
3.8
3.1
15.59
48.72
e6/l
1.31
28
286
15
140
1.08
0.04
1.9
1.4
—
—
—
0
0
12
111
1.09
0.04
4.3
3.3
—
—
—
0
0
125
1244
1.02
0.00
5.0
4.2
6.03
5.83
mmol/l
0.68
113
1156
16
157
1.02
0.00
1.6
1.3
—
—
—
0
0
21
215
0.97
0.00
3.4
3.5
12.83
96.09
ng/l
1.16
12
150
17
172
0.99
0.00
1.2
1.2
—
—
—
0
0
6
61
0.98
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
92
0.98
-0.00
2.8
2.2
13.32
13.59
nmol/l
—
9
87
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
44.90
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
13.48
—
0
6
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
115.17
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
44.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
10.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.3
—
3.96
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX – Benign neoplasm: Pelvic bones, sacrum and coccyx

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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