Benign neoplasm: Pelvic bones, sacrum and coccyx

CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D16.8&
  • Hospital discharge: ICD-9 2136
  • Hospital discharge: ICD-8 21305
  • Cause of death: ICD-10 D16.8&
  • Cause of death: ICD-9 2136
  • Cause of death: ICD-8 21305

2 out of 7 registries used, show all original rules.

140

4. Check minimum number of events

None

140

5. Include endpoints

None

140

6. Filter based on genotype QC (FinnGen only)

140

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum ossis coxae, ossis sacri sive ossis coccygis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 995 538 448
Only index persons 868 483 385
Unadjusted period prevalence (%)
Whole population 0.01 0.02 0.01
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 40.90 43.81 37.09
Only index persons 39.57 42.49 35.90

-FinnGen-

Key figures

All Female Male
Number of individuals 140 90 50
Unadjusted period prevalence (%) 0.03 0.03 0.02
Median age at first event (years) 44.38 42.95 46.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
114
Matched controls
1141
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.8
ICD-10 Finland
Benign neoplasm: Pelvic bones, sacrum and coccyx
+∞
106.6
85
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
35.5
18.3
23
8
21305
ICD-8 Finland
Benign neoplasm of bone and cartilage, Pelvis, sacri, coccygis
+∞
17.1
16
*
NER20
NOMESCO Finland
Incomplete excision of soft tissue tumour of pelvis
+∞
16.0
15
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
18.6
15.7
24
16
2136A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Pelvic bones, sacrum and coccyx
+∞
14.9
14
*
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
42.7
12.5
15
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
72.6
11.9
13
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
8.1
11.0
25
38
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
+∞
8.4
8
*
9102
FHL
Trepanation or removal of the local bone process
48.4
7.8
9
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
8.5
7.2
15
20
NEA20
NOMESCO Finland
Exploration of soft tissue of pelvis,v
73.8
6.5
7
*
9101
FHL
Bone biopsy
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
99
670
2.63
6.40
7.7
9.6
3.9
4.0
e9/l
0.21
93
579
72
465
2.13
4.61
6.0
5.1
1.2
1.2
mmol/l
0.15
67
429
113
874
2.52
4.59
3.9
4.0
15.1
14.8
pmol/l
0.90
106
792
21
78
2.99
4.49
5.7
4.3
—
—
—
0
0
79
533
2.11
4.46
4.5
3.6
0.0
0.0
estimate
0.00
14
113
84
580
2.12
4.46
6.0
5.3
2.0
2.0
e9/l
0.04
75
516
66
421
2.07
4.28
4.2
3.4
—
—
—
0
0
108
846
2.21
3.83
4.7
3.9
8.6
10.6
mm/h
1.54
102
778
80
563
1.98
3.81
6.1
5.4
0.0
0.0
e9/l
0.69
71
493
17
62
2.98
3.74
1.4
2.9
—
—
—
0
0
79
562
1.93
3.56
6.2
5.4
0.6
0.6
e9/l
0.02
71
491
100
772
2.03
3.53
5.1
4.0
—
—
—
0
0
81
583
1.92
3.50
6.2
5.6
0.2
0.2
e9/l
0.82
73
521
77
546
1.91
3.48
4.5
3.6
0.0
0.0
estimate
0.00
13
107
76
539
1.90
3.41
5.4
4.9
0.0
0.0
estimate
0.00
15
113
125
1060
2.67
3.38
5.0
4.6
1.7
1.9
mu/l
1.02
117
970
47
286
1.97
3.32
6.1
7.8
—
—
—
0
0
51
322
1.92
3.22
3.6
3.0
—
—
—
0
0
8
16
5.23
3.10
1.0
5.6
—
—
—
0
0
41
244
1.96
3.06
1.7
2.1
2.8
3.0
mg/l
0.33
33
207
52
339
1.85
2.94
2.3
2.5
56.3
58.4
u/l
0.21
47
311
21
99
2.32
2.82
2.0
2.0
449.2
368.4
nmol/l
1.13
21
90
84
643
1.77
2.70
4.8
4.2
6.4
6.5
mmol/l
0.16
78
588
26
138
2.09
2.63
2.2
2.1
—
—
—
0
0
62
440
1.73
2.57
2.2
1.9
—
—
—
0
0
58
404
1.74
2.57
2.0
1.8
102.8
97.2
pmol/l
0.35
32
206
78
591
1.72
2.54
5.8
6.2
9.4
10.6
umol/l
1.21
73
561
58
406
1.73
2.51
3.5
3.6
17.8
31.2
ng/l
1.32
39
259
44
287
1.78
2.42
6.0
3.8
0.0
0.0
estimate
0.00
14
112
19
93
2.21
2.34
3.3
4.3
—
—
—
0
0
128
1146
2.36
2.21
18.2
13.8
139.9
139.7
mmol/l
0.48
123
1116
128
1151
2.31
2.10
18.3
13.9
4.0
3.9
mmol/l
0.65
123
1119
52
370
1.64
2.04
3.8
3.5
2.4
2.4
mmol/l
0.11
47
326
37
242
1.72
1.98
5.6
3.6
—
—
—
0
0
41
276
1.69
1.98
7.6
4.5
—
—
—
0
0
14
66
2.25
1.89
1.1
1.3
69.7
181.8
u/ml
0.99
14
59
44
307
1.63
1.84
2.8
3.1
—
—
—
0
0
5
12
4.28
1.84
1.2
1.2
—
—
—
0
0
5
12
4.28
1.84
1.2
1.2
—
—
—
0
0
5
12
4.28
1.84
1.2
3.8
—
—
—
0
0
46
325
1.62
1.83
4.3
3.8
7.4
7.4
ph
0.08
11
60
48
344
1.60
1.80
2.3
2.1
—
—
—
0
0
42
292
1.63
1.78
1.4
1.2
0.6
1.0
u/ml
0.64
15
82
50
363
1.59
1.78
6.1
5.1
—
—
—
0
0
5
13
3.95
1.73
1.0
1.5
—
—
—
0
0
5
13
3.95
1.73
1.2
1.2
—
—
—
0
0
53
393
1.56
1.71
9.2
6.9
1.1
1.2
inr
0.18
16
129
128
1170
2.10
1.68
16.1
12.5
18.9
22.5
mg/l
0.73
108
900
11
50
2.30
1.61
2.4
2.1
—
—
—
0
0
31
205
1.66
1.58
1.4
1.3
24.0
31.6
iu/ml
—
8
72
66
521
1.50
1.57
10.5
8.6
0.0
0.0
e9/l
0.27
57
419
131
1222
2.12
1.53
16.2
11.4
—
—
—
0
0
41
294
1.56
1.51
4.2
3.7
—
—
—
0
0
63
498
1.48
1.47
3.0
2.5
125.8
99.0
ug/l
0.28
58
456
6
22
2.80
1.45
1.2
1.7
—
—
—
0
0
12
60
2.09
1.43
1.0
1.1
—
—
—
0
0
20
122
1.75
1.36
2.1
1.5
—
—
—
0
0
36
257
1.54
1.34
4.7
4.1
—
—
—
0
0
8
34
2.43
1.31
1.5
1.6
—
—
—
0
0
8
36
2.29
1.26
4.6
4.3
—
—
—
0
0
5
19
2.69
1.22
1.0
1.5
—
—
—
0
0
18
111
1.71
1.19
1.7
2.1
—
—
—
0
0
18
113
1.68
1.12
6.1
6.1
105.6
103.9
mmol/l
1.12
18
108
20
131
1.61
1.07
1.3
1.2
—
—
—
0
0
11
60
1.90
1.06
1.5
1.8
—
—
—
0
0
5
22
2.32
1.04
3.2
2.3
—
—
—
0
0
128
1204
1.74
1.02
19.8
14.4
73.8
74.3
umol/l
0.10
128
1204
9
49
1.89
1.01
1.0
1.3
—
—
—
0
0
115
1059
1.48
0.98
4.1
3.8
1.3
1.2
mmol/l
0.19
108
980
34
256
1.43
0.98
1.7
1.7
3.7
0.9
mg/l
0.42
23
195
34
258
1.42
0.94
1.9
1.3
1.8
2.3
g/l
1.86
23
149
35
268
1.41
0.92
4.2
3.1
18.6
67.3
mg/l
0.94
24
168
15
95
1.65
0.92
1.3
1.5
—
—
—
0
0
27
197
1.46
0.91
1.3
1.3
27.3
6.1
u/ml
0.65
17
77
13
80
1.69
0.88
1.5
1.4
—
—
—
0
0
86
762
1.33
0.87
4.3
3.6
—
—
—
0
0
10
57
1.81
0.86
4.3
4.7
—
—
—
0
0
36
282
1.37
0.83
5.3
3.9
1.9
9.3
mg/mmol
1.35
25
180
120
1126
1.46
0.80
5.1
4.6
2.6
2.8
mmol/l
1.98
115
1047
118
1104
1.44
0.79
4.6
4.2
1.4
1.5
mmol/l
0.68
113
1030
6
34
1.80
0.77
1.2
1.3
0.2
0.2
g/l
—
6
34
7
38
1.89
0.75
2.4
1.4
12.9
6.4
u/l
—
7
33
9
58
1.59
0.71
9.6
4.3
24.7
24.8
mmol/l
—
9
58
118
1111
1.40
0.69
4.7
4.2
4.4
4.7
mmol/l
3.31
113
1044
5
27
1.88
0.69
1.4
1.4
1.2
36.8
e6/l
—
5
20
5
27
1.88
0.69
1.4
1.4
13.0
2.6
e6/l
—
5
19
12
78
1.59
0.68
7.5
5.8
—
—
—
0
0
5
28
1.81
0.67
4.8
2.8
5.2
5.0
kpa
—
5
28
5
28
1.81
0.67
4.8
2.8
9.6
8.2
kpa
—
5
28
37
305
1.29
0.60
3.2
2.9
—
—
—
0
0
0
21
0.00
0.60
0.0
2.2
—
—
—
0
0
6
35
1.75
0.58
10.2
13.5
—
—
—
0
0
11
74
1.53
0.55
1.3
1.2
—
—
—
0
0
14
102
1.41
0.49
7.8
6.8
4.8
5.1
kpa
0.60
14
97
46
399
1.23
0.49
4.9
3.7
16.4
45.6
e6/l
1.60
34
271
7
46
1.55
0.49
3.9
3.8
25.6
24.5
mmol/l
—
7
46
7
48
1.48
0.47
1.1
1.2
—
—
—
0
0
36
307
1.23
0.45
3.4
2.9
2.2
0.4
e6/l
0.50
29
222
33
279
1.24
0.44
1.9
2.0
—
—
—
0
0
40
347
1.21
0.42
1.5
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
8
61
1.33
0.40
3.3
3.3
5.3
5.1
kpa
—
8
55
5
35
1.44
0.39
1.2
1.3
1.1
1.2
g/l
—
5
35
18
143
1.30
0.39
2.8
2.6
0.5
0.8
ug/l
1.36
11
80
18
144
1.29
0.37
1.3
1.5
—
—
—
0
0
12
90
1.36
0.37
2.8
3.5
—
—
—
0
0
6
44
1.38
0.35
2.8
3.4
—
—
—
0
0
19
158
1.23
0.30
1.8
1.5
—
—
—
0
0
12
95
1.29
0.27
1.3
1.3
—
—
—
0
0
11
137
0.79
0.25
1.1
1.3
—
—
—
0
0
12
96
1.27
0.25
4.5
3.2
—
—
—
0
0
11
87
1.29
0.25
2.9
3.5
6.1
5.8
kpa
0.30
11
87
25
221
1.16
0.22
1.5
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
0.9
—
0
12
0
12
0.00
0.21
0.0
2.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
106.1
—
0
14
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
4.0
—
0
14
0
14
0.00
0.20
0.0
3.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
6
51
1.18
0.19
1.3
2.2
—
—
—
0
0
6
52
1.16
0.19
1.0
1.7
—
—
—
0
0
6
52
1.16
0.19
1.0
1.2
—
—
—
0
0
10
83
1.22
0.16
1.4
1.5
—
—
—
0
0
17
152
1.13
0.13
1.2
1.2
—
—
—
0
0
105
1030
1.08
0.10
7.0
5.3
40.3
39.3
mmol/mol
0.46
98
966
5
43
1.17
0.10
1.8
2.3
—
—
—
0
0
5
48
1.04
0.09
2.6
3.8
—
—
—
0
0
7
63
1.12
0.08
1.3
1.6
—
—
—
0
0
7
63
1.12
0.08
1.3
1.6
—
—
—
0
0
7
63
1.12
0.08
1.1
1.7
—
—
—
0
0
7
63
1.12
0.08
1.3
1.7
—
—
—
0
0
8
74
1.09
0.07
2.3
3.0
74.8
69.2
e9/l
—
8
57
21
196
1.08
0.07
3.4
3.3
12.8
98.4
ng/l
1.05
12
136
7
80
0.87
0.07
1.0
1.2
—
—
—
0
0
108
1092
0.95
0.05
14.8
13.0
40.5
40.4
%
0.06
77
846
14
130
1.09
0.05
1.6
1.2
—
—
—
0
0
35
339
1.04
0.04
3.9
3.1
15.7
51.7
e6/l
1.27
27
254
17
161
1.06
0.03
1.4
1.7
—
—
—
0
0
11
103
1.07
0.02
1.9
1.4
—
—
—
0
0
46
452
1.03
0.02
3.0
2.7
—
—
—
0
0
12
124
0.96
0.00
2.1
1.4
—
—
—
0
0
110
1095
1.02
0.00
4.9
4.2
6.0
5.8
mmol/l
0.35
99
1017
10
95
1.06
0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.6
—
52.8
—
0
9
0
9
0.00
0.00
0.0
9.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
9.6
—
1142.4
—
0
9
0
9
0.00
0.00
0.0
12.9
—
2225.0
—
0
9
0
5
0.00
0.00
0.0
1.2
—
44.6
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
3.3
—
4.0
—
0
7
7
69
1.02
0.00
3.9
2.9
3.7
4.4
kpa
—
7
69
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
44.9
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
110.0
—
0
5
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
6
59
1.02
0.00
1.2
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
11.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_PELVIC_BONES_SACRUM_COCCYX – Benign neoplasm: Pelvic bones, sacrum and coccyx

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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