Benign neoplasm: Lower jaw bone

CD2_BENIGN_BONE_LOWER_JAW

lip cancer: Tumors or cancer of the LIP.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D16.50&, D16.51& Hospital discharge: ICD-9 — 2131 Hospital discharge: ICD-8 — 21300 Cause of death: ICD-10 — D16.50&, D16.51& Cause of death: ICD-9 — 2131 Cause of death: ICD-8 — 21300 2 out of 7 registries used, show all original rules.	155
4. Check minimum number of events None	155
5. Include endpoints None	155
6. Filter based on genotype QC (FinnGen only)	152

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	CD2_BENIGN_BONE_LOWER_JAW
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D165
HD_ICD_9	2131
HD_ICD_8	21300
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D165
COD_ICD_9	2131
COD_ICD_8	21300
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Lower jaw bone based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1354	749	590
Only index persons	1186	664	522
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.02
Only index persons	0.02	0.02	0.02
Median age at first event (years)
Whole population	40.31	42.78	36.91
Only index persons	37.44	40.64	33.38

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	152	96	56
Unadjusted period prevalence (%)	0.03	0.03	0.03
Median age at first event (years)	42.51	41.48	44.27

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
155: Matched controls
1550

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D16.50

ICD-10 Finland

Benign tumor of the mandibular bone or cartilage

+∞

71.5

D16.51

ICD-10 Finland

Benign tumor of the mandibular bone with urpsrung in teeth

+∞

61.7

WZC10

NOMESCO Finland

Written specialist consultation based on a referral from a dentist or a physician

11.7

25.8

EDA10

NOMESCO Finland

Biopsy of mandible

+∞

25.7

21300

ICD-8 Finland

Benign neoplasm of bone and cartilage, Mandibulae (detibus inclusis)

+∞

25.7

WZC05

NOMESCO Finland

Specialty-specific consultation based on referral by dentist or doctor

8.8

23.5

EFA10

NOMESCO Finland

Excision of lesion of jaws

+∞

22.4

SAA04

NOMESCO Finland

Special examination of mouth

9.1

20.2

EFA50

NOMESCO Finland

Excision of cyst of jaws

60.2

18.5

2131A

ICD-9 Finland

Benign neoplasm of bone and articular cartilage, Lower jaw bone

+∞

15.9

D16.5

ICD-10 Finland

Benign neoplasm: Lower jaw bone

+∞

14.8

SAA03

NOMESCO Finland

Extended examination of mouth

3.6

13.9

470

EDB00

NOMESCO Finland

Partial excision of mandible

+∞

13.7

EB1AI

NOMESCO Finland

Cone beam imaging of teeth and jaws (one quarter)

17.4

13.0

EBB10

NOMESCO Finland

Insertion of dental implant

76.3

12.8

K08.1

ICD-10 Finland

Loss of teeth due to accident, extraction or local periodontal disease

4.6

12.4

WZC00

NOMESCO Finland

Treatment plan or consultation

3.2

11.6

394

EBA10

NOMESCO Finland

Operative extraction of tooth

3.8

10.8

125

SXB00

NOMESCO Finland

Removal of sutures from oral mucosa

4.8

9.0

EB1BI

NOMESCO Finland

Cone beam imaging of teeth and jaws (1–2 quarters)

29.4

8.6

K09.29

ICD-10 Finland

Cyst of jaw traumatic

83.9

7.5

EDC45

NOMESCO Finland

Reconstruction of mandible using bone graft

+∞

7.3

SPA00

NOMESCO Finland

Changing form of teeth in prepation for prosthodontic work

6.9

7.2

SXC03

NOMESCO Finland

Other oral or dental procedure

41.9

6.8

EBB15

NOMESCO Finland

Insertion of dental implant abutment

27.9

6.3

4332

FHL

Lower jaw resection or tumor removal

+∞

6.3

K09.02

ICD-10 Finland

Cyst lateral periodontal

+∞

6.3

EB1AD

NOMESCO Finland

Cone beam CT of teeth and jaws (one quarter)

+∞

6.3

K03.66

ICD-10 Finland

Tooth plaque

4.0

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3020779) Urea [Moles/volume] in Serum or Plasma

2.93

4.74

3.7

6.9

7.27

8.64

mmol/l

0.52

(40768804) Tissue Pathology biopsy report

504

1.85

3.45

2.3

2.0

—

(40768797) Stomach Pathology biopsy report

159

2.19

3.40

1.4

1.3

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

107

2.35

3.16

2.3

2.6

0.24

0.22

g/l

0.68

102

(3044640) Blood type and Crossmatch panel - Blood

384

1.77

2.80

2.3

2.2

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

6.41

2.39

1.0

1.4

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

5.70

2.23

1.0

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

3.46

2.21

3.0

2.5

24.49

24.09

mmol/l

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

293

1.65

1.94

2.5

2.0

2.83

2.95

mg/l

0.12

259

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.20

1.93

9.7

4.1

22.45

25.29

mmol/l

3.12

(3003458) Phosphate [Moles/volume] in Serum or Plasma

146

1.85

1.92

3.4

5.4

1.02

1.06

mmol/l

0.43

134

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

1.89

0.0

1.8

—

(3044290) Cell count panel - Cerebral spinal fluid

2.96

1.89

1.1

1.5

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

4.27

1.83

1.0

1.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

441

1.55

1.80

3.6

3.7

29.04

28.34

ng/l

0.03

287

(3000494) Fungus identified in Specimen by Culture

144

1.79

1.70

1.3

1.4

—

(3021901) Oxygen saturation in Capillary blood

3.24

1.68

3.0

2.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

283

1.56

1.53

2.1

2.2

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.52

1.50

1.4

1.6

—

(3021440) Promyelocytes/100 leukocytes in Blood

1.87

1.46

9.2

4.4

0.00

0.23

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

112

1.79

1.43

2.5

4.0

4.11

11.20

ug/l

0.98

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

244

1.56

1.43

1.5

1.8

461.57

471.13

pmol/l

0.05

210

(3002256) Pathology report gross observation

152

1.69

1.42

1.2

1.3

—

(4094501) Cardiovascular stress test using bicycle ergometer

2.67

1.38

1.0

1.1

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

3.00

1.37

1.4

2.4

3.03

7.44

u/ml

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

2.56

1.31

3.2

2.6

0.30

0.41

u/ml

—

(3025159) Blasts/100 leukocytes in Blood

1.82

1.31

9.7

4.4

0.00

0.33

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

312

1.47

1.28

3.0

3.1

1371.43

1094.89

ng/l

0.18

262

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

102

893

1.42

1.23

2.9

3.4

—

(1616796) Gas panel - Central venous blood

2.36

1.20

2.8

2.7

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

335

1.44

1.17

2.1

2.0

143.34

167.93

u/l

0.33

322

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

129

1186

1.52

1.14

14.1

12.1

85.31

84.75

ml/min/173m2

0.09

112

970

(3020564) Creatinine [Moles/volume] in Serum or Plasma

142

1337

1.74

1.10

16.5

14.9

74.15

74.12

umol/l

0.01

142

1337

(3017181) Myelocytes/100 leukocytes in Blood

106

1.68

1.08

9.2

4.1

0.38

0.81

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

198

1.51

1.08

2.8

3.2

0.85

0.81

mmol/l

0.86

183

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.90

1.06

1.7

1.6

—

(4035726) Immunohistochemistry procedure

107

1.66

1.05

1.1

1.3

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

2.31

1.04

2.6

3.0

12.00

47.64

u/ml

—

(3042936) Bacteria identified in Isolate by Culture

183

1.51

1.02

1.4

2.0

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

108

970

1.37

1.01

4.1

4.0

14.45

14.75

pmol/l

0.56

884

(40768443) Skin Pathology biopsy report

1.85

0.98

1.0

1.1

—

(3002179) Metamyelocytes/100 leukocytes in Blood

1.68

0.98

9.9

4.3

0.00

0.38

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

585

1.32

0.93

2.6

2.5

—

(3023368) Bacteria identified in Blood by Culture

304

1.38

0.91

4.3

4.2

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

2.11

0.90

1.3

2.6

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

1.95

0.90

1.6

2.9

0.00

g/l

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

2.04

0.88

1.2

—

(3007853) Bacteria identified in Skin by Aerobe culture

138

1.52

0.87

1.7

1.6

—

(3013290) Carbon dioxide [Partial pressure] in Blood

1.97

0.85

3.2

3.3

4.63

4.91

kpa

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

1.97

0.85

1.8

3.1

172.50

185.65

—

(3027315) Oxygen [Partial pressure] in Blood

1.97

0.85

3.2

3.3

9.08

8.51

kpa

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.78

0.84

1.8

2.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

151

0.57

0.83

1.6

1.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

132

1.50

0.80

1.4

1.7

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.80

0.0

1.3

—

25.13

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.79

0.0

4.6

—

23.87

—

(40758558) Short blood count panel - Blood

321

1.33

0.77

5.5

7.4

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.79

0.77

7.8

3.6

68.87

46.73

mg/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.79

0.77

7.7

3.6

21.18

27.74

mg/l

—

(3012516) Albumin [Mass/volume] in Urine

314

1.32

0.74

3.0

80.10

68.68

mg/l

0.09

192

(3036489) Thrombin time

1.83

0.73

1.4

2.5

21.86

22.12

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

1.78

0.72

1.3

2.9

0.00

g/l

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

1.78

0.72

1.3

2.9

0.00

g/l

—

(3003694) ABO and Rh group [Type] in Blood

353

1.30

0.71

1.4

1.6

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

429

1.28

0.70

3.1

3.2

58.29

31.73

u/l

0.57

411

(3026782) Osmolality of Urine

253

1.33

0.68

2.4

2.8

575.26

548.07

mosm/kgh2o

0.21

220

(3022217) INR in Platelet poor plasma by Coagulation assay

536

1.26

0.68

16.2

11.4

1.26

1.19

inr

0.23

168

(3044889) 12 lead EKG panel

844

1.25

0.67

4.2

3.6

—

(3022145) Colonoscopy Study observation

130

1.44

0.65

1.4

1.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

339

1.28

0.64

3.6

3.7

13.91

10.78

mg/mmol

0.12

203

(3009508) Creatinine [Moles/volume] in Urine

349

1.28

0.63

3.3

3.0

6.88

7.32

mmol/l

0.26

300

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

161

0.66

0.61

1.1

1.5

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.61

0.0

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.60

0.0

1.6

—

(36304419) Bacteria [Presence] in Urine

342

1.27

0.60

2.3

2.9

—

(3021589) Normoblasts [#/volume] in Blood

582

1.23

0.60

11.3

9.8

0.00

e9/l

-0.00

473

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

277

1.29

0.59

1.6

1.8

0.61

1.21

mg/l

1.67

213

(3007566) Smooth muscle Ab [Titer] in Serum

1.74

0.58

1.5

1.1

—

50.00

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

133

1.40

0.58

1.4

1.8

—

(3034770) Mitochondria Ab [Titer] in Serum

1.69

0.57

1.5

1.1

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.69

0.57

1.3

1.1

—

(3018095) Leukocytes [#/volume] in Urine

451

1.23

0.54

3.4

3.7

13.92

59.87

e6/l

1.91

322

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.48

0.54

1.7

1.3

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.56

0.53

1.2

—

(3049717) Cytology report of Urine Cyto stain

1.56

0.53

2.8

2.6

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.45

0.53

3.0

2.4

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.43

0.52

15.8

7.4

95.07

94.29

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

292

1.26

0.51

4.3

3.7

—

(3015736) pH of Urine

512

1.21

0.51

3.6

3.4

5.86

5.88

—

(40761511) CBC panel - Blood by Automated count

138

1329

1.35

0.50

14.4

12.2

—

(3026493) Urate [Moles/volume] in Serum or Plasma

293

1.25

0.50

3.6

3.0

354.07

5435.33

umol/l

1.25

257

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

1.43

0.50

3.2

3.0

43.80

66.14

ml/min/173m2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.48

0.49

2.0

1.8

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.55

0.49

1.0

1.3

—

(3045414) Leukocytes [Presence] in Urine

1.42

0.45

1.9

1.5

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

194

1.28

0.45

1.8

1.9

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

0.65

0.44

1.2

1.3

—

27.21

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

1.63

0.43

1.4

1.6

—

(3005719) IgG [Mass/volume] in Serum or Plasma

105

1.37

0.43

1.5

2.8

9.66

9.73

g/l

0.03

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.42

0.42

1.9

1.5

—

(40768793) Breast Pathology biopsy report

1.53

0.41

1.2

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.41

0.0

3.5

—

(3009261) Glucose [Presence] in Urine by Test strip

639

1.17

0.41

3.9

3.6

0.00

estimate

-0.00

122

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.37

0.41

1.2

1.5

—

(1002224) Polysomnography panel

1.33

0.40

1.1

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.40

0.0

1.0

—

0.46

—

(3007461) Platelets [#/volume] in Blood

145

1414

1.39

0.39

22.7

19.4

248.75

251.40

e9/l

0.20

145

1380

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.36

0.39

15.8

7.0

0.61

0.74

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.40

0.38

1.4

1.8

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.40

0.38

1.2

1.3

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.34

0.38

15.8

7.0

1.00

1.52

—

(3024731) MCV [Entitic volume]

145

1415

1.38

0.38

22.6

19.3

90.60

90.74

0.15

145

1394

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

274

1.21

0.38

1.4

1.6

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.28

0.37

2.6

2.8

—

(3023520) Reticulocytes [#/volume] in Blood

1.34

0.37

1.6

2.7

52.24

71.65

e9/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

634

1.16

0.36

5.1

4.9

0.00

estimate

-0.00

124

(3035350) Ketones [Presence] in Urine by Test strip

634

1.16

0.36

4.0

3.6

0.00

estimate

-0.00

128

(3026361) Erythrocytes [#/volume] in Blood

145

1416

1.37

0.36

22.7

19.3

4.46

4.50

e12/l

0.52

145

1376

(3035941) MCH [Entitic mass]

145

1416

1.37

0.36

22.7

19.2

30.11

30.23

0.41

145

1395

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.48

0.36

1.0

1.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

163

1.26

0.36

1.5

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.45

0.36

4.3

1.5

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

210

1.23

0.35

1.2

1.3

0.78

9.12

u/ml

—

(3010813) Leukocytes [#/volume] in Blood

145

1417

1.36

0.35

22.6

19.4

6.44

6.60

e9/l

0.46

145

1375

(3002582) Erythrocytes [#/volume] in Urine

392

1.17

0.34

2.7

3.1

11.08

195.50

e6/l

0.60

307

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.32

0.33

1.7

1.6

—

(3029937) Albumin [Presence] in Urine by Test strip

345

1.17

0.33

4.8

3.8

0.00

estimate

-0.00

116

(3030467) Casts [#/volume] in Urine by Automated count

345

1.17

0.33

2.4

3.1

0.21

0.33

e6/l

0.60

261

(40761536) Microorganisms panel - Urine sediment

110

1.30

0.33

2.9

3.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

374

1.17

0.33

2.7

3.0

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

307

1.18

0.32

1.4

1.3

0.37

0.70

u/ml

3.87

(3000963) Hemoglobin [Mass/volume] in Blood

145

1419

1.34

0.32

23.1

19.4

133.45

135.59

g/l

1.10

145

1395

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.71

0.32

1.3

1.5

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.34

0.31

15.3

7.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

602

1.14

0.30

6.8

6.6

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

583

1.14

0.29

7.0

6.6

1.20

1.22

mmol/l

0.71

497

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

131

1.25

0.28

1.8

1.7

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.29

0.27

2.1

1.9

—

(3006315) Basophils [#/volume] in Blood

634

0.89

0.26

7.3

6.0

0.04

e9/l

0.43

559

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.27

0.26

1.1

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.23

0.26

1.1

1.8

—

(4200892) Spirometry reversibility

0.71

0.24

1.2

1.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.71

0.24

1.2

1.0

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

530

1.12

0.24

7.1

5.6

1.21

1.22

mmol/l

0.54

487

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

452

1.12

0.23

2.8

3.1

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.29

0.23

1.4

1.7

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.26

0.22

1.8

2.6

—

(3013707) Erythrocyte sedimentation rate by Westergren method

921

1.11

0.22

4.0

4.1

12.73

10.34

mm/h

0.75

847

(3022096) Basophils/100 leukocytes in Blood

572

1.11

0.22

6.8

5.8

0.55

0.66

0.82

543

(21494755) Public health laboratory ask at order entry panel

145

1.19

0.21

1.2

1.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

464

1.11

0.21

2.2

1.9

104.61

97.34

pmol/l

0.68

222

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.21

0.0

7.6

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.2

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.21

0.0

3.2

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.1

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.3

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

0.21

0.0

1.5

—

9.03

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

1.05

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.21

0.0

3.9

—

(3019198) Lymphocytes [#/volume] in Blood

648

0.90

0.21

7.2

6.1

1.64

1.90

e9/l

1.33

587

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

0.21

0.0

2.1

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

0.21

0.0

2.1

—

(3011951) Aspergillus fumigatus IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

0.18

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3014037) CD3+CD4+ (T4 helper) cells/100 cells in Blood

0.00

0.21

0.0

3.6

—

48.50

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

176

0.84

0.21

2.3

2.7

0.83

0.79

ug/l

—

115

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

1.2

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

3.08

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.21

0.0

1.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.26

0.20

2.2

2.1

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.20

0.0

2.6

—

33.85

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.20

0.0

3.0

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

127

1240

1.13

0.20

5.0

4.6

2.70

2.79

mmol/l

0.50

118

1147

(3022621) pH of Urine by Test strip

1.25

0.19

2.0

2.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

735

1.09

0.19

8.0

10.2

4.21

4.01

e9/l

0.27

648

(3001604) Monocytes [#/volume] in Blood

634

0.91

0.18

7.1

6.0

0.55

0.56

e9/l

0.15

560

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.17

0.18

2.6

2.8

2.00

1.36

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

508

1.10

0.18

4.2

3.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

167

1.16

0.18

1.8

2.0

—

(3006504) Eosinophils/100 leukocytes in Blood

590

1.08

0.16

6.6

5.9

2.67

2.80

0.17

563

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

140

1.16

0.15

10.1

7.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

120

1173

1.10

0.15

4.2

3.7

1.30

1.29

mmol/l

0.05

112

1079

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

0.80

0.15

4.4

4.0

109.57

73.82

ng/l

—

(3013512) EKG study

335

1.10

0.14

4.3

4.0

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

404

1.09

0.14

3.2

3.3

2.34

2.36

mmol/l

0.26

362

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

124

1217

1.09

0.13

4.5

4.1

1.46

1.48

mmol/l

0.15

115

1125

(3026008) Bacteria identified in Urine by Culture

367

1.08

0.12

2.7

3.1

—

(3019069) Monocytes/100 leukocytes in Blood

596

1.07

0.11

6.9

6.2

9.16

8.37

0.87

570

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

222

1.10

0.10

3.8

3.3

309.13

174.19

ng/l

0.20

156

(3000991) Gas panel - Venous blood

1.16

0.10

17.6

6.1

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

120

1180

1.08

0.10

5.0

4.6

1.74

1.83

mu/l

0.44

113

1083

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

207

0.91

0.10

2.4

2.8

1.09

0.97

e6/l

0.07

119

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.11

0.10

2.6

1.9

—

(3016879) Cocaine [Presence] in Urine

1.04

0.09

6.4

1.8

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

122

1202

1.07

0.09

4.7

4.2

5.95

5.83

mmol/l

0.41

114

1101

(3013115) Eosinophils [#/volume] in Blood

650

1.05

0.09

6.7

6.2

0.18

0.19

e9/l

0.05

581

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

185

1.09

0.08

1.8

2.1

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

124

1223

1.07

0.08

4.6

4.2

4.56

4.68

mmol/l

0.67

115

1138

(3018418) pH of Serum or Plasma

363

1.06

0.08

3.7

4.3

7.40

0.27

(3019060) Gas panel - Arterial blood

0.84

0.08

3.2

4.1

—

(3019225) pH of Specimen

108

1.12

0.07

2.7

4.3

—

(3025941) Bacteria identified in Stool by Culture

1.09

0.07

1.3

1.2

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

116

1144

1.06

0.07

6.2

5.2

39.95

39.40

mmol/mol

0.26

111

1076

(3019832) Treponema pallidum Ab [Presence] in Serum

152

0.91

0.06

1.6

1.7

—

(3002030) Lymphocytes/100 leukocytes in Blood

614

1.04

0.06

6.8

6.0

28.17

28.29

0.02

589

(3000492) Spirometry study

120

1.09

0.05

1.2

1.4

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

211

1.05

0.03

1.3

105.76

25.15

iu/ml

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

229

0.95

0.03

1.5

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

122

1.07

0.03

2.8

3.5

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

128

1271

1.04

0.02

15.9

13.0

26.59

21.86

mg/l

0.67

110

969

(3014576) Chloride [Moles/volume] in Serum or Plasma

138

0.94

0.02

11.8

6.1

106.00

104.27

mmol/l

0.43

138

(3002385) Erythrocyte distribution width [Ratio]

112

1129

0.97

0.02

18.3

15.8

14.71

14.57

0.11

112

1114

(1761868) Lipid panel - Serum or Plasma

471

1.03

0.02

2.8

2.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

236

0.97

0.00

1.4

—

(36660697) Celiac disease serology panel - Serum

1.01

0.00

1.0

1.1

—

(40761535) Cells panel - Urine sediment

1.01

0.00

5.9

3.3

—

(3019309) Folate [Moles/volume] in Red Blood Cells

204

0.98

0.00

1.6

1.7

1403.27

1197.85

nmol/l

0.34

150

(46235355) HIV 1 and 2 tests - Meaningful Use set

274

0.98

0.00

1.7

1.9

—

(3007164) IgA [Mass/volume] in Serum or Plasma

281

1.00

0.00

1.5

1.4

2.45

2.24

g/l

0.46

167

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

197

1.02

0.00

2.9

3.0

1.55

3.04

e6/l

0.79

109

(3037467) Urinalysis macro (dipstick) panel - Urine

853

0.99

0.00

3.7

4.2

—

(3018010) Neutrophils/100 leukocytes in Blood

606

1.01

0.00

6.8

5.8

57.34

57.05

0.06

579

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.8

—

(3000330) Specific gravity of Urine by Test strip

0.91

0.00

2.3

3.1

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

1.6

—

969.25

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.6

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.9

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

37.92

—

(3028300) Cannabinoids [Presence] in Urine

0.94

0.00

6.4

1.7

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

0.0

1.4

—

30.84

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.0

1.0

—

92.13

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3048518) aPTT.lupus sensitive actual/normal (normalized LA screen)

0.00

-0.00

0.0

1.0

—

(3001501) Glucose [Moles/volume] in Capillary blood by Glucometer

0.00

-0.00

0.0

1.2

—

5.86

—

(3010375) cycloSPORINE [Mass/volume] in Blood

0.00

-0.00

0.0

28.3

—

84.33

—

(3013293) Extractable nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

25.20

—

(3000764) Benzodiazepines [Presence] in Urine

0.92

-0.00

6.6

1.7

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

-0.00

0.0

4.6

—

(3022313) Gas panel - Capillary blood

0.94

-0.00

2.0

2.8

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

4.0

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

-0.00

0.0

2.0

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

-0.00

0.0

2.2

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.3

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.0

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(40758292) HTLV I+II Ab panel - Serum

0.00

-0.00

0.0

1.6

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3000919) Neutrophils/100 leukocytes in Pleural fluid

0.00

-0.00

0.0

1.0

—

47.40

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

-0.00

0.0

2.4

—

77.48

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

59.56

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3001893) Eosinophils/100 leukocytes in Pleural fluid

0.00

-0.00

0.0

1.0

—

2.14

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

6.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.89

-0.00

1.3

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.87

-0.00

1.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.3

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

1.8

—

2330.00

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

54.40

—

(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

24.00

—

(3027944) Amphetamines [Presence] in Urine

0.92

-0.00

9.0

1.7

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.1

—

0.62

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.4

—

3.72

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3024263) Appearance of Synovial fluid

0.00

-0.00

0.0

1.0

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

7.16

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

0.33

—

(3009876) Amylase isoenzyme 3 panel - Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.0

—

6.29

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.87

-0.00

3.0

2.8

0.52

0.67

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

1.58

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.3

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

0.86

-0.00

1.0

2.3

—

9768.31

u/l

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

230

1.00

-0.00

3.4

4.5

22.63

23.10

—

106

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_BONE_LOWER_JAW and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BONE_LOWER_JAW.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_BONE_LOWER_JAW – Benign neoplasm: Lower jaw bone

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Lower jaw bone

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints