lip cancer: Tumors or cancer of the LIP.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
148 |
4. Check minimum number of eventsNone |
148 |
5. Include endpointsNone |
148 |
6. Filter based on genotype QC (FinnGen only) |
148 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Lower jaw bone
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Lower jaw bone
- Benign neoplasm of bone and articular cartilage
- Benign neoplasm of bone and articular cartilage
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1354 | 749 | 590 |
| Only index persons | 1186 | 664 | 522 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 40.31 | 42.78 | 36.91 |
| Only index persons | 37.44 | 40.64 | 33.38 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 148 | 95 | 53 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | 40.91 | 41.21 | 40.36 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 140
- Matched controls
- 1401
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.50
ICD-10 Finland
Benign tumor of the mandibular bone or cartilage
+∞
58.5
52
*
D16.51
ICD-10 Finland
Benign tumor of the mandibular bone with urpsrung in teeth
+∞
56.1
50
*
21300
ICD-8 Finland
Benign neoplasm of bone and cartilage, Mandibulae (detibus inclusis)
+∞
24.7
23
*
EFA10
NOMESCO Finland
Excision of lesion of jaws
+∞
20.3
19
*
EDA10
NOMESCO Finland
Biopsy of mandible
122.5
20.2
21
*
2131A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Lower jaw bone
+∞
15.9
15
*
EFA50
NOMESCO Finland
Excision of cyst of jaws
33.0
15.7
20
7
D16.5
ICD-10 Finland
Benign neoplasm: Lower jaw bone
+∞
14.8
14
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
8.9
14.6
32
45
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
10.3
14.1
28
33
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
24.1
13.8
19
9
SAA03
NOMESCO Finland
Extended examination of mouth
3.6
11.6
82
396
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
11.6
11
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
8.2
11.5
26
38
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.6
11.1
70
306
EBB10
NOMESCO Finland
Insertion of dental implant
18.6
8.2
12
7
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
8.4
7.6
16
21
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
21.4
7.2
10
5
EBA10
NOMESCO Finland
Surgical removal of tooth
3.7
7.0
31
99
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.0
6.7
27
79
SXC03
NOMESCO Finland
Other oral or dental procedure
28.1
6.3
8
*
4332
FHL
Lower jaw resection or tumor removal
+∞
6.3
6
*
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
103
2.33
2.99
2.3
2.7
0.2
0.2
g/l
0.82
22
98
25
133
2.06
2.50
3.4
5.7
1.0
1.1
mmol/l
0.44
25
123
8
24
3.46
2.21
3.0
2.5
24.5
23.7
mmol/l
—
8
18
0
50
0.00
1.93
0.0
1.9
—
—
—
0
0
9
35
2.67
1.83
1.4
1.6
—
—
—
0
0
40
274
1.63
1.78
2.4
2.0
3.0
3.0
mg/l
0.02
31
241
39
271
1.60
1.63
2.2
2.2
—
—
—
0
0
56
424
1.52
1.60
3.6
3.7
30.2
27.4
ng/l
0.12
34
276
0
42
0.00
1.55
0.0
1.2
—
—
—
0
0
13
65
2.10
1.54
11.0
4.3
22.3
25.3
mmol/l
2.84
13
65
34
232
1.60
1.53
1.5
1.8
461.6
476.6
pmol/l
0.09
28
201
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
6
22
2.80
1.45
3.2
2.4
0.3
0.4
u/ml
—
6
14
41
299
1.51
1.38
3.1
3.1
1371.4
1125.8
ng/l
0.16
35
253
18
108
1.76
1.29
2.6
4.1
4.4
11.6
ug/l
0.95
12
85
11
56
2.04
1.25
1.7
1.5
—
—
—
0
0
27
185
1.56
1.19
2.9
3.2
0.9
0.8
mmol/l
0.83
27
172
123
1127
1.54
1.15
14.1
12.2
84.9
84.5
ml/min/173m2
0.05
106
919
42
319
1.44
1.15
2.1
2.1
144.0
170.7
u/l
0.34
42
307
104
929
1.40
1.07
4.1
4.0
14.5
14.8
pmol/l
0.49
95
846
96
848
1.38
1.04
3.0
3.4
—
—
—
0
0
5
22
2.32
1.04
2.6
3.0
12.0
47.6
u/ml
—
5
22
135
1275
1.67
0.96
16.7
15.0
74.2
74.2
umol/l
0.01
135
1275
8
42
1.96
0.90
1.6
2.9
0.0
0.0
g/l
—
8
42
6
30
2.04
0.88
1.2
1.2
—
—
—
0
0
8
46
1.78
0.84
1.8
2.7
—
—
—
0
0
6
33
1.85
0.80
7.7
3.6
21.2
27.7
mg/l
—
6
27
6
33
1.85
0.80
7.8
3.6
68.9
46.7
mg/l
—
6
27
35
275
1.36
0.78
3.6
3.1
354.1
5841.4
umol/l
1.25
29
238
18
125
1.50
0.77
1.4
1.7
—
—
—
0
0
7
40
1.79
0.72
1.3
2.9
0.0
0.0
g/l
—
7
40
7
40
1.79
0.72
1.3
2.9
0.0
0.0
g/l
—
7
40
64
558
1.26
0.66
4.1
3.9
—
—
—
0
0
5
29
1.75
0.64
1.4
1.7
—
—
—
0
0
5
30
1.69
0.62
1.8
3.0
172.6
186.8
%
—
5
30
0
23
0.00
0.59
0.0
1.3
—
26.2
—
0
18
6
37
1.65
0.56
1.2
1.2
—
—
—
0
0
9
60
1.53
0.55
1.7
1.3
—
—
—
0
0
17
126
1.39
0.54
1.5
1.8
—
—
—
0
0
13
92
1.45
0.52
3.2
3.1
43.8
65.2
ml/min/173m2
—
5
36
11
75
1.50
0.52
1.9
1.6
—
—
—
0
0
23
183
1.30
0.48
1.8
1.9
—
—
—
0
0
32
267
1.25
0.47
1.6
1.8
0.5
1.2
mg/l
2.47
24
206
25
203
1.28
0.46
1.2
1.3
0.8
9.3
u/ml
—
8
89
47
411
1.21
0.45
3.3
3.2
60.9
31.9
u/l
0.57
47
394
5
33
1.53
0.41
1.4
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
99
933
1.18
0.40
6.9
7.4
83.9
76.2
u/l
0.48
94
874
5
35
1.44
0.39
1.2
1.3
—
—
—
0
0
9
66
1.39
0.39
15.8
7.0
1.0
1.5
%
—
9
66
5
36
1.40
0.38
1.4
1.8
—
—
—
0
0
123
1184
1.23
0.37
5.0
4.6
2.7
2.8
mmol/l
0.41
115
1098
6
41
1.48
0.36
4.3
1.5
—
—
—
0
0
30
257
1.21
0.36
1.4
1.6
—
—
—
0
0
6
45
1.35
0.34
2.2
2.1
—
—
—
0
0
55
502
1.15
0.32
7.4
5.7
1.2
1.2
mmol/l
0.60
50
455
66
613
1.14
0.29
3.9
3.7
0.0
0.0
estimate
0.00
17
117
138
1351
1.32
0.29
22.8
19.5
133.4
135.5
g/l
1.00
138
1328
116
1120
1.17
0.28
4.1
3.7
1.3
1.3
mmol/l
0.12
108
1034
120
1162
1.17
0.27
4.5
4.2
1.5
1.5
mmol/l
0.26
112
1077
49
448
1.14
0.27
2.2
1.9
105.6
96.9
pmol/l
0.86
30
214
92
876
1.13
0.27
4.0
4.2
13.2
10.5
mm/h
0.85
86
805
16
132
1.24
0.27
10.1
7.5
—
—
—
0
0
65
607
1.13
0.26
4.0
3.7
0.0
0.0
estimate
0.00
19
122
9
73
1.25
0.26
2.1
1.8
—
—
—
0
0
65
608
1.12
0.25
5.2
5.0
0.0
0.0
estimate
0.00
17
119
15
125
1.22
0.23
1.7
1.7
—
—
—
0
0
5
38
1.33
0.23
1.8
2.6
—
—
—
0
0
5
40
1.26
0.22
1.0
1.2
—
—
—
0
0
118
1147
1.14
0.22
4.8
4.2
6.0
5.8
mmol/l
0.49
110
1055
120
1168
1.14
0.22
4.5
4.2
4.6
4.7
mmol/l
0.62
111
1089
59
553
1.11
0.21
7.5
6.7
1.2
1.2
mmol/l
0.72
48
464
5
42
1.20
0.21
2.6
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
8.7
—
0
5
32
289
1.14
0.21
1.4
1.3
0.4
0.7
u/ml
4.01
14
72
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
3.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
36
330
1.12
0.19
4.9
3.9
0.0
0.0
estimate
0.00
17
113
36
330
1.12
0.19
2.4
3.2
0.2
0.3
e6/l
0.16
30
248
42
389
1.11
0.19
3.3
3.2
2.3
2.4
mmol/l
0.18
36
344
7
58
1.22
0.18
2.6
2.9
2.0
1.4
%
—
7
58
73
697
1.09
0.18
8.3
10.2
4.3
4.0
e9/l
0.40
63
613
18
159
1.15
0.16
1.8
2.0
—
—
—
0
0
113
1104
1.10
0.15
15.9
13.5
39.6
40.1
%
0.34
83
844
46
433
1.09
0.15
2.8
3.1
—
—
—
0
0
112
1094
1.10
0.15
6.4
5.2
40.0
39.3
mmol/mol
0.32
107
1031
18
200
0.89
0.13
2.4
2.9
1.2
1.0
e6/l
—
10
114
115
1127
1.09
0.13
5.0
4.6
1.7
1.8
mu/l
0.34
109
1033
22
204
1.09
0.09
1.3
1.3
105.8
25.4
iu/ml
—
9
74
102
1039
0.94
0.09
18.7
16.2
13.8
13.6
%
0.63
102
1022
6
74
0.80
0.08
1.2
1.0
—
—
—
0
0
7
84
0.83
0.07
4.4
4.0
109.6
73.7
ng/l
—
7
75
19
178
1.08
0.06
1.9
2.1
—
—
—
0
0
50
486
1.04
0.05
4.3
3.6
—
—
—
0
0
10
91
1.11
0.04
2.2
1.8
—
—
—
0
0
122
1211
1.04
0.03
15.5
13.1
27.0
21.9
mg/l
0.71
106
923
22
227
0.96
0.01
1.4
1.4
—
—
—
0
0
12
116
1.04
0.00
3.0
3.6
—
—
—
0
0
13
134
0.97
0.00
11.8
6.2
106.0
104.1
mmol/l
0.46
13
127
10
101
0.99
0.00
6.8
3.5
-1.4
2.2
mmol/l
—
10
74
20
196
1.02
0.00
1.6
1.6
1403.3
1197.3
nmol/l
0.34
15
144
21
208
1.01
0.00
3.4
4.5
22.6
22.9
%
—
7
93
19
192
0.99
0.00
2.8
3.0
1.7
3.1
e6/l
—
10
106
0
5
0.00
0.00
0.0
2.4
—
77.5
—
0
5
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
0.3
—
0
5
0
8
0.00
0.00
0.0
1.6
—
969.3
—
0
8
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
4.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
7
72
0.97
0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
24.0
—
0
5
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
92.1
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BONE_LOWER_JAW and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BONE_LOWER_JAW.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_LOWER_JAW – Benign neoplasm: Lower jaw bone
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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