Benign neoplasm: Short bones of upper limb

CD2_BENIGN_BONE_SHORT_UPPER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D16.1&
  • Hospital discharge: ICD-9 2135
  • Hospital discharge: ICD-8 21304
  • Cause of death: ICD-10 D16.1&
  • Cause of death: ICD-9 2135
  • Cause of death: ICD-8 21304

2 out of 7 registries used, show all original rules.

566

4. Check minimum number of events

None

566

5. Include endpoints

None

566

6. Filter based on genotype QC (FinnGen only)

566

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum ossium brevium membri superioris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4153 2166 1973
Only index persons 3902 2072 1830
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.06
Only index persons 0.07 0.08 0.07
Median age at first event (years)
Whole population 38.27 40.19 36.12
Only index persons 38.06 40.09 35.77

-FinnGen-

Key figures

All Female Male
Number of individuals 566 357 209
Unadjusted period prevalence (%) 0.11 0.12 0.09
Median age at first event (years) 43.74 43.28 44.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
508
Matched controls
5081
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
+∞
323.0
375
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
82.8
141.7
156
27
2135A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of upper limb
+∞
89.2
83
*
21304
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis superioris
+∞
59.6
56
*
9102
FHL
Trepanation or removal of the local bone process
52.1
53.8
64
14
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
32.8
46.5
61
21
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
6.3
42.9
126
252
NDK10
NOMESCO Finland
Incision or excision of a bone of hand
106.0
28.0
30
*
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
24.2
24.2
34
15
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
13.8
23.8
41
32
WX204
NOMESCO Finland
Axillary plexus blockaced
8.3
22.2
50
66
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
76.6
19.8
22
*
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
57.3
19.1
22
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
26.7
17.0
23
9
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
93.2
16.7
18
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
7.9
16.2
37
50
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
16.4
15.9
25
16
9104
FHL
Autogenous bone graft
+∞
13.6
13
*
ND3CG
NOMESCO Finland
Extensive MRI of fingers
61.3
10.7
12
*
WX203
NOMESCO Finland
Infraclavicular plexus blockade
6.3
10.1
26
43
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
30.6
9.4
12
*
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
8.9
9.4
19
22
ND2CG
NOMESCO Finland
Extensive MRI of hand
19.0
9.0
13
7
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
9.0
240
1697
ND1AA
NOMESCO Finland
Wrist X-ray examination
3.3
8.9
44
141
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
91.5
8.4
9
*
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
+∞
8.4
8
*
M25.5
ICD-10 Finland
Pain in joint
1.8
8.1
158
1000
M01AH05
ATC
etoricoxib; oral
1.7
8.0
313
2447
ZZH20
NOMESCO Finland
Graft of patients own bone
12.1
7.6
13
11
NDK00
NOMESCO Finland
Excision or incsion of a bone of wrist
25.4
7.6
10
*
ND1DG
NOMESCO Finland
Wrist and hand very extensive MRI examination with high intensity magnet
30.5
7.2
9
*
ZZH40
NOMESCO Finland
Substitute of bone
7.3
6.7
15
21
SPAT1153
SPAT
Removal of sutures
1.7
6.6
155
1030
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.2
6.5
19
38
X58
ICD-10 Finland
Exposure to other specified factors
2.1
6.5
79
418
S62.6
ICD-10 Finland
Fracture of other finger
3.1
6.5
34
116
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
+∞
6.3
6
*
ZXA05
NOMESCO Finland
Left side
1.8
6.0
116
723

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
261
1956
1.62
7.24
2.1
2.0
—
—
—
0
0
134
848
1.76
7.05
1.3
1.3
12.5
10.4
u/ml
0.12
47
360
173
1192
1.65
6.60
2.3
2.5
3989.5
5048.4
umol/l
0.13
142
1059
133
871
1.69
6.11
1.4
1.3
22.5
27.6
iu/ml
0.31
33
295
413
3539
1.62
5.96
4.4
3.9
10.1
10.8
mm/h
0.45
384
3277
198
1504
1.49
4.63
5.3
5.7
—
—
—
0
0
170
1252
1.51
4.62
3.8
3.4
—
—
—
0
0
143
1018
1.54
4.54
2.4
2.0
2.8
3.0
mg/l
0.27
121
881
62
363
1.80
4.19
1.2
1.2
—
—
—
0
0
364
3164
1.42
3.85
4.3
4.0
—
—
—
0
0
407
3612
1.45
3.82
7.0
7.4
72.9
77.7
u/l
2.72
384
3386
230
1855
1.40
3.72
4.2
4.7
36.6
36.1
g/l
0.74
208
1751
99
678
1.56
3.70
1.4
1.3
694.5
526.8
titre
0.23
22
141
411
3665
1.44
3.67
4.2
3.9
14.8
14.6
pmol/l
1.00
383
3370
476
4385
1.54
3.46
5.0
4.6
6.9
2.1
mu/l
0.46
438
4061
515
4844
1.70
3.30
13.6
13.7
139.8
139.7
mmol/l
0.17
501
4720
516
4858
1.70
3.26
13.8
13.8
4.0
4.0
mmol/l
0.00
499
4729
250
2085
1.36
3.16
2.9
2.7
102.0
115.6
ug/l
0.62
227
1949
289
2470
1.35
3.08
5.4
6.0
0.2
0.2
e9/l
1.52
259
2191
63
409
1.61
2.96
3.3
4.2
—
—
—
0
0
508
4787
1.60
2.91
12.8
12.5
22.8
21.8
mg/l
0.23
418
3705
206
1684
1.35
2.91
1.9
1.9
100.9
95.9
pmol/l
0.68
105
892
97
700
1.47
2.82
1.8
1.7
1054.1
1213.2
nmol/l
1.27
79
529
52
327
1.65
2.78
2.3
2.7
3.9
4.1
e9/l
0.29
42
270
298
2593
1.32
2.66
3.6
4.4
6.4
6.6
mmol/l
1.04
278
2425
527
5030
1.69
2.62
12.4
11.7
—
—
—
0
0
281
2434
1.31
2.56
5.6
5.7
2.1
1.9
e9/l
0.44
251
2176
83
594
1.47
2.52
1.3
1.3
—
—
—
0
0
181
1479
1.33
2.50
2.9
3.3
2.3
2.4
mmol/l
0.21
153
1321
140
1105
1.35
2.43
1.4
1.3
2.7
1.6
u/ml
0.22
38
317
274
2377
1.30
2.42
5.5
5.7
0.0
0.0
e9/l
0.64
240
2082
85
618
1.44
2.38
2.0
2.2
2.4
2.4
g/l
0.01
79
569
23
119
1.97
2.34
3.0
3.0
—
—
—
0
0
265
2297
1.29
2.33
4.4
4.5
0.0
0.0
estimate
0.50
60
451
248
2133
1.29
2.31
5.1
6.5
1.2
1.2
mmol/l
1.06
201
1813
91
674
1.42
2.31
1.9
2.3
14.8
13.7
umol/l
0.72
80
618
146
1169
1.34
2.30
2.9
2.7
—
—
—
0
0
272
2369
1.29
2.29
5.5
5.7
0.6
0.6
e9/l
0.02
239
2074
89
658
1.42
2.28
1.2
1.2
—
—
—
0
0
251
2168
1.28
2.25
3.7
3.9
—
—
—
0
0
14
60
2.37
2.23
1.4
1.3
—
—
—
0
0
267
2326
1.28
2.23
3.4
3.3
0.0
0.0
estimate
0.80
54
430
5
9
5.59
2.21
1.2
2.0
—
—
—
0
0
31
183
1.73
2.12
1.7
1.2
—
—
—
0
0
103
791
1.37
2.12
3.0
3.6
151.0
409.6
ng/l
1.40
66
562
225
1929
1.28
2.10
4.4
5.6
1.2
1.2
mmol/l
0.81
201
1756
83
617
1.40
2.07
2.8
2.4
172.5
117.9
ug/g
0.83
57
495
77
566
1.42
2.05
2.0
2.3
25.0
23.2
%
0.50
61
491
261
2285
1.26
2.04
3.5
3.3
0.0
0.0
estimate
0.00
58
446
112
877
1.35
2.04
1.4
1.7
494.2
16510498.8
pmol/l
0.78
80
745
200
1702
1.27
1.96
4.9
7.1
1.1
1.2
inr
0.51
46
528
173
1448
1.28
1.94
2.7
2.4
55.2
56.4
u/l
0.20
150
1348
257
2258
1.25
1.91
5.7
5.6
55.5
56.7
%
1.02
237
2133
133
1078
1.31
1.90
2.2
2.1
—
—
—
0
0
484
4595
1.37
1.88
4.5
4.2
5.8
5.9
mmol/l
0.31
445
4243
77
577
1.39
1.85
1.5
1.6
—
—
—
0
0
70
520
1.40
1.77
1.4
1.6
—
—
—
0
0
258
2285
1.24
1.74
6.0
5.8
29.2
28.5
%
0.50
237
2148
15
75
2.03
1.71
1.4
1.5
—
—
—
0
0
251
2229
1.23
1.62
6.2
6.0
8.4
8.5
%
0.05
231
2103
499
4783
1.37
1.61
4.4
4.2
4.7
4.8
mmol/l
0.41
463
4480
120
982
1.28
1.59
1.5
1.4
2.2
2.3
g/l
0.56
70
628
483
4610
1.33
1.59
4.0
3.8
1.3
1.3
mmol/l
0.42
440
4293
242
2145
1.22
1.58
5.9
5.7
0.7
0.7
%
0.08
222
2009
33
216
1.56
1.58
1.1
1.1
—
—
—
0
0
22
130
1.72
1.55
1.2
1.1
—
—
—
0
0
249
2218
1.22
1.54
5.9
5.7
3.1
2.8
%
1.15
228
2070
191
1657
1.23
1.52
2.9
3.2
21.7
33.9
ng/l
0.88
120
1033
23
139
1.68
1.50
3.6
2.6
—
—
—
0
0
51
370
1.42
1.50
1.2
1.2
223.2
156.6
iu/ml
0.38
26
152
527
5109
1.46
1.48
10.7
9.9
26.4
27.1
u/l
0.54
509
4954
9
38
2.39
1.46
1.4
1.1
—
—
—
0
0
7
28
2.52
1.45
1.9
2.8
—
—
—
0
0
11
52
2.14
1.45
1.5
1.3
—
—
—
0
0
154
1312
1.24
1.45
1.7
2.1
110.7
184.3
u/l
4.33
146
1238
18
103
1.77
1.42
1.4
1.2
—
—
—
0
0
144
1222
1.24
1.40
3.3
3.4
26.7
214.0
mg/l
1.30
94
798
141
1194
1.24
1.40
3.1
2.8
0.4
0.4
e6/l
0.04
108
892
21
334
0.61
1.39
1.7
1.7
—
—
—
0
0
53
394
1.38
1.37
3.5
3.4
—
—
—
0
0
144
1226
1.23
1.36
3.7
3.5
0.0
0.0
estimate
0.88
56
439
0
37
0.00
1.35
0.0
2.8
—
46.6
—
0
11
298
2729
1.19
1.31
7.5
9.1
3.8
4.0
e9/l
1.26
259
2412
45
605
0.72
1.30
1.3
1.4
—
—
—
0
0
547
5357
1.63
1.29
19.8
18.4
259.3
253.6
e9/l
1.24
533
5242
547
5358
1.62
1.27
19.7
18.4
91.0
90.8
fl
0.42
538
5297
8
35
2.30
1.27
1.4
1.3
—
—
—
0
0
494
4760
1.30
1.27
4.4
4.2
1.5
1.5
mmol/l
0.06
455
4441
547
5359
1.62
1.26
19.6
18.3
30.3
30.3
pg
0.37
538
5297
13
70
1.88
1.25
1.5
1.4
—
—
—
0
0
6
25
2.41
1.24
1.2
1.5
149.5
152.1
nmol/l
—
6
25
547
5360
1.61
1.24
19.7
18.4
4.5
4.5
e12/l
0.02
533
5233
547
5361
1.61
1.23
19.8
18.5
6.7
6.6
e9/l
0.32
532
5231
30
205
1.49
1.22
2.4
2.3
—
—
—
0
0
109
912
1.24
1.21
2.3
2.3
5.3
6.4
e6/l
0.35
92
801
547
5363
1.59
1.19
19.8
18.5
136.7
136.6
g/l
0.13
539
5298
23
149
1.57
1.19
2.7
3.6
0.2
0.2
g/l
—
9
59
67
529
1.30
1.19
5.0
5.6
1.0
1.0
mmol/l
0.06
62
497
10
50
2.02
1.17
2.0
1.6
—
—
—
0
0
0
33
0.00
1.16
0.0
1.6
—
—
—
0
0
155
1353
1.20
1.14
3.0
3.2
8.0
7.8
mmol/l
0.24
123
1132
151
1316
1.20
1.12
3.0
2.9
90.5
107.2
e6/l
0.07
113
1015
8
40
2.01
1.12
1.8
2.8
—
—
—
0
0
69
552
1.28
1.12
1.6
1.3
—
—
—
0
0
44
330
1.36
1.11
1.3
1.4
—
—
—
0
0
54
420
1.32
1.08
2.9
2.1
335.1
364.6
nmol/l
0.59
48
392
16
97
1.67
1.07
1.1
1.1
—
—
—
0
0
16
97
1.67
1.07
1.1
1.1
—
—
—
0
0
7
33
2.13
1.06
2.0
1.3
—
—
—
0
0
131
1135
1.20
1.04
3.1
3.6
92.6
93.8
%
0.24
126
1106
47
361
1.33
1.03
1.2
1.5
—
—
—
0
0
120
1034
1.20
1.01
3.5
3.3
—
—
—
0
0
140
1224
1.19
1.01
4.5
4.4
1.9
2.2
ug/l
0.61
130
1106
501
4864
1.26
0.99
4.8
4.6
2.8
2.9
mmol/l
0.87
461
4533
14
84
1.68
0.98
1.6
2.2
126.7
132.6
g/l
—
9
63
347
3266
1.16
0.97
3.5
3.4
—
—
—
0
0
14
85
1.66
0.95
1.4
2.9
2.3
2.6
mmol/l
—
5
59
9
51
1.78
0.95
1.2
1.7
90.0
90.9
%
—
9
51
44
341
1.31
0.92
2.4
3.6
1.2
1.2
mmol/l
1.06
37
296
455
4383
1.19
0.92
5.5
5.3
38.6
39.4
mmol/mol
1.33
413
4114
173
1552
1.17
0.91
3.4
3.4
53.4
77.7
e6/l
0.46
124
1094
147
1303
1.17
0.90
2.9
2.9
—
—
—
0
0
89
754
1.21
0.90
2.7
2.7
2.4
2.4
mmol/l
1.46
77
670
6
29
2.08
0.89
1.3
1.2
—
—
—
0
0
160
1433
1.16
0.86
2.2
2.2
—
—
—
0
0
44
345
1.30
0.86
3.1
3.4
—
—
—
0
0
6
115
0.52
0.83
1.0
1.2
—
—
—
0
0
6
33
1.83
0.79
1.0
1.1
155.2
226.5
mg/l
—
6
28
0
26
0.00
0.78
0.0
4.8
—
—
—
0
0
24
174
1.40
0.78
2.5
2.2
105.6
3594.3
u/l
—
5
67
145
1299
1.16
0.78
4.0
4.1
2.9
8.1
mg/mmol
3.37
89
824
0
27
0.00
0.77
0.0
2.1
—
8.7
—
0
22
69
583
1.21
0.74
1.3
1.4
—
—
—
0
0
7
38
1.85
0.73
1.0
1.5
1.3
1.3
promille
—
7
28
46
373
1.25
0.72
3.0
2.6
9.6
10.2
g/l
0.56
38
343
122
1086
1.16
0.71
3.4
4.3
—
—
—
0
0
53
438
1.23
0.70
2.3
2.8
1.8
1.8
%
0.01
45
398
104
916
1.17
0.70
1.8
1.8
—
—
—
0
0
7
42
1.67
0.68
1.0
1.2
—
—
—
0
0
62
523
1.21
0.68
1.8
2.7
7.3
7.4
umol/l
0.02
50
456
33
261
1.28
0.64
2.9
2.5
—
—
—
0
0
5
29
1.73
0.64
3.2
4.7
24.3
46.4
mu/l
—
5
29
13
87
1.51
0.63
1.5
2.7
—
—
—
0
0
19
138
1.39
0.63
1.1
1.2
—
—
—
0
0
6
105
0.57
0.62
5.7
4.3
—
—
—
0
0
52
436
1.21
0.62
4.2
7.9
4.9
5.2
kpa
1.54
47
421
52
436
1.21
0.62
4.2
7.9
11.8
12.4
kpa
0.51
47
423
21
277
0.75
0.61
2.6
2.3
21.4
41.4
u/ml
1.18
21
264
15
209
0.71
0.60
4.1
3.2
—
—
—
0
0
27
210
1.30
0.60
4.9
9.3
—
—
—
0
0
11
72
1.54
0.59
1.3
1.2
22.9
15.8
u/l
0.25
11
60
16
114
1.42
0.59
2.1
2.3
34.5
123.5
ug/min
—
8
63
52
439
1.20
0.58
4.2
7.9
0.8
1.3
mmol/l
0.58
40
354
24
308
0.77
0.58
2.6
2.5
4.3
4.9
kpa
0.72
24
298
11
161
0.68
0.58
1.4
1.2
—
—
—
0
0
5
89
0.56
0.56
1.6
2.4
—
—
—
0
0
21
159
1.33
0.56
1.6
1.6
—
—
—
0
0
18
239
0.75
0.55
2.7
2.6
0.1
0.1
e6/l
0.73
18
231
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
109
987
1.13
0.52
3.9
3.5
1.0
1.0
kg/l
0.19
20
122
106
960
1.13
0.50
1.5
1.5
22.4
20.8
nmol/l
0.37
88
817
14
190
0.73
0.50
1.6
2.3
0.7
0.7
%
0.16
14
185
123
1339
0.90
0.48
1.4
1.4
—
—
—
0
0
40
337
1.20
0.48
1.8
2.3
3.5
7.8
ug/l
2.75
32
306
7
48
1.46
0.47
4.6
1.4
—
—
—
0
0
33
274
1.22
0.46
1.2
1.2
—
—
—
0
0
11
152
0.72
0.44
9.2
7.4
—
—
—
0
0
32
382
0.83
0.44
2.5
3.3
—
—
—
0
0
134
1242
1.10
0.43
2.8
2.7
—
—
—
0
0
38
323
1.19
0.42
5.0
7.8
—
—
—
0
0
118
1088
1.11
0.42
1.6
1.7
0.9
1.1
mg/l
0.37
87
840
31
259
1.21
0.41
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
45
390
1.17
0.41
1.4
1.4
—
—
—
0
0
93
848
1.12
0.41
2.6
2.5
534.3
559.0
mosm/kgh2o
0.43
77
727
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
5
34
1.47
0.40
3.0
1.8
2.1
3.8
mg/l
—
5
34
222
2113
1.08
0.40
8.2
8.5
0.0
0.0
e9/l
0.52
183
1737
16
204
0.78
0.39
1.1
1.5
—
—
—
0
0
16
203
0.78
0.38
1.1
1.5
—
—
—
0
0
16
203
0.78
0.38
1.1
1.5
—
—
—
0
0
9
66
1.37
0.38
1.4
1.3
—
30.1
—
0
5
16
202
0.79
0.37
1.1
1.5
—
—
—
0
0
5
37
1.35
0.37
1.2
1.3
35.8
32.6
g/l
—
5
32
5
37
1.35
0.37
1.2
1.1
—
—
—
0
0
9
70
1.29
0.37
1.4
1.9
—
—
—
0
0
10
135
0.74
0.36
1.2
2.0
—
—
—
0
0
126
1176
1.09
0.36
4.5
4.6
—
—
—
0
0
9
122
0.73
0.35
1.9
4.0
3.7
3.9
mmol/l
—
9
110
6
43
1.40
0.35
2.7
2.3
—
—
—
0
0
18
145
1.25
0.34
1.1
1.2
—
—
—
0
0
6
46
1.31
0.33
3.0
2.3
—
—
—
0
0
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
10
132
0.75
0.32
1.7
1.3
—
—
—
0
0
29
248
1.18
0.32
2.3
5.1
—
—
—
0
0
11
83
1.33
0.32
2.0
2.5
15.3
16.7
%
—
5
43
7
52
1.35
0.31
2.3
2.4
—
—
—
0
0
7
96
0.73
0.31
5.4
3.6
3.6
4.3
e9/l
—
7
96
7
98
0.71
0.31
5.4
3.9
56.0
56.7
%
—
7
98
7
54
1.30
0.30
1.9
2.6
—
—
—
0
0
7
54
1.30
0.30
1.0
1.3
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
13
102
1.28
0.30
1.0
1.3
—
—
—
0
0
45
501
0.89
0.28
5.2
6.5
104.7
104.1
mmol/l
0.53
45
485
250
2416
1.06
0.28
5.5
6.2
11.7
10.7
umol/l
0.30
229
2288
33
374
0.88
0.27
1.5
1.4
—
—
—
0
0
49
541
0.90
0.27
1.6
1.4
—
—
—
0
0
33
373
0.88
0.27
2.4
3.3
6.1
5.8
kpa
1.53
33
363
8
66
1.22
0.27
1.3
1.1
—
—
—
0
0
5
71
0.70
0.26
1.4
1.7
47.2
64.2
%
—
5
71
33
370
0.89
0.24
2.6
3.3
2.0
1.9
mmol/l
0.02
28
292
136
1297
1.06
0.23
3.7
3.9
7.4
7.4
ph
0.30
33
239
35
314
1.12
0.23
1.2
1.2
—
—
—
0
0
7
91
0.77
0.22
1.0
1.1
—
—
—
0
0
80
750
1.08
0.22
1.6
1.6
—
—
—
0
0
5
40
1.25
0.22
1.0
1.4
1.1
1.0
g/l
—
5
40
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
10
79
1.27
0.22
1.3
1.4
—
—
—
0
0
401
4074
0.95
0.22
14.3
15.1
13.6
13.6
%
0.01
394
4002
5
42
1.19
0.21
11.2
2.4
—
—
—
0
0
23
201
1.15
0.21
3.2
3.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
20
173
1.16
0.21
1.2
1.3
147.8
226.0
miu/ml
—
10
84
22
192
1.15
0.21
1.5
1.6
—
—
—
0
0
46
422
1.10
0.21
4.1
4.4
13.6
19.0
ug/l
0.16
38
348
31
278
1.12
0.20
2.8
2.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.0
1.3
—
—
—
0
0
16
186
0.86
0.19
1.1
1.5
—
—
—
0
0
10
81
1.24
0.19
1.3
1.2
—
—
—
0
0
7
58
1.21
0.18
2.1
1.7
—
—
—
0
0
7
58
1.21
0.18
2.1
1.7
—
—
—
0
0
7
58
1.21
0.18
2.1
1.7
—
—
—
0
0
7
58
1.21
0.18
2.1
1.7
—
—
—
0
0
7
58
1.21
0.18
1.0
1.3
—
—
—
0
0
7
60
1.17
0.18
1.4
1.1
—
—
—
0
0
7
61
1.15
0.17
1.0
1.3
0.5
0.6
nmol/l
—
7
56
5
66
0.76
0.17
1.2
1.0
2.4
3.1
u/ml
—
5
21
34
311
1.10
0.17
2.6
2.9
73.2
73.4
e9/l
0.01
27
230
6
79
0.76
0.15
1.3
1.5
—
—
—
0
0
10
83
1.21
0.15
5.6
4.0
—
—
—
0
0
9
78
1.16
0.15
1.1
1.2
—
—
—
0
0
121
1167
1.05
0.15
6.0
6.5
—
—
—
0
0
9
82
1.10
0.15
1.0
1.0
—
—
—
0
0
446
4501
0.96
0.14
13.7
13.0
40.0
40.3
%
0.29
326
3452
36
387
0.93
0.14
4.2
3.9
0.2
0.7
%
—
10
90
192
1964
0.97
0.13
2.6
2.6
—
—
—
0
0
13
114
1.14
0.12
4.7
3.6
29.1
28.3
mg/l
0.03
13
92
13
114
1.14
0.12
4.7
3.6
26.4
92.3
mg/l
0.63
13
92
121
1246
0.96
0.11
1.6
1.7
1.5
1.4
mmol/l
0.27
106
1058
10
86
1.17
0.11
1.1
1.8
—
—
—
0
0
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
10
87
1.15
0.09
1.5
1.2
—
—
—
0
0
7
67
1.05
0.08
1.0
1.1
1.4
1.5
g/l
—
7
60
6
74
0.81
0.07
1.2
1.1
—
—
—
0
0
8
78
1.03
0.07
1.8
2.2
—
—
—
0
0
66
640
1.04
0.07
1.9
2.0
—
—
—
0
0
52
502
1.04
0.07
1.6
1.4
—
—
—
0
0
8
90
0.89
0.07
1.0
1.8
—
—
—
0
0
9
103
0.87
0.06
1.3
1.4
—
—
—
0
0
41
425
0.96
0.05
4.1
4.0
1.2
1.0
%
0.21
13
125
14
149
0.94
0.03
2.1
4.4
—
—
—
0
0
31
300
1.04
0.03
1.7
1.8
1.2
1.3
g/l
0.14
26
279
12
128
0.94
0.02
2.3
2.4
11.4
11.6
mg/l
0.05
12
121
55
541
1.02
0.02
1.5
1.7
—
—
—
0
0
28
272
1.03
0.02
3.3
3.0
7.4
7.4
ph
—
5
35
12
113
1.06
0.02
1.0
1.2
3.3
3.7
mmol/l
3.02
12
105
10
104
0.96
0.00
3.0
2.3
8.4
8.3
kpa
—
10
98
40
395
1.01
0.00
4.1
4.1
0.1
0.2
%
0.57
13
111
15
153
0.98
0.00
1.1
1.6
—
—
—
0
0
47
475
0.99
0.00
1.9
1.6
—
—
—
0
0
48
485
0.99
0.00
27.6
18.2
1.3
1.3
inr
—
9
71
10
98
1.02
0.00
1.6
1.7
—
—
—
0
0
12
122
0.98
0.00
1.8
1.9
6.7
6.1
iu/l
—
6
44
72
724
0.99
0.00
2.8
2.8
0.6
0.7
ug/l
1.85
50
447
38
378
1.01
0.00
4.0
4.1
0.0
0.2
%
—
10
94
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
5
52
0.96
0.00
3.2
1.9
35.4
33.1
pg
—
5
52
0
8
0.00
0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
15.9
—
0
5
0
7
0.00
0.00
0.0
4.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
5.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
40.0
—
0
6
5
54
0.93
0.00
1.4
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
0.00
2.9
2.5
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
67.9
—
0
7
0
5
0.00
0.00
0.0
6.2
—
0.3
—
0
5
0
6
0.00
0.00
0.0
3.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
5
50
1.00
0.00
1.0
1.3
—
—
—
0
0
9
94
0.96
0.00
1.4
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
2.0
2.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
1.8
—
0
9
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_BONE_SHORT_UPPER and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SHORT_UPPER 0.944 [0.72, 1.23] 0.672
Birth year 0.997 [0.99, 1.01] 0.516

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 1306 females with CD2_BENIGN_BONE_SHORT_UPPER died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SHORT_UPPER 1.044 [0.83, 1.31] 0.71
Birth year 0.988 [0.98, 1.0] 0.016

During the follow-up period (1.1.1998 — 31.12.2019), 86 out of 1186 males with CD2_BENIGN_BONE_SHORT_UPPER died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BONE_SHORT_UPPER.

N-year risk Females Males
1 0.111% 0.233%
5 0.545% 1.21%
10 1.497% 3.125%
15 2.917% 5.91%
20 5.199% 10.258%

Relationships between endpoints

Index endpoint: CD2_BENIGN_BONE_SHORT_UPPER – Benign neoplasm: Short bones of upper limb

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data