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Retinal haemorrhage

DOID EFO Endpoint Browser PheWeb

H7_RETINAHAEMORR

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H35.6
  • Hospital discharge: ICD-9 — 3628A
  • Hospital discharge: ICD-8 — 37701
  • Cause of death: ICD-10 — H35.6
  • Cause of death: ICD-9 — 3628A
  • Cause of death: ICD-8 — 37701

2 out of 7 registries used, show all original rules.

940

4. Check minimum number of events

None

940

5. Include endpoints

None

940

6. Filter based on genotype QC (FinnGen only)

908

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H35
Name in latin
Haemorrhagia retinae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6470 3761 2664
Only index persons 5746 3425 2321
Unadjusted period prevalence (%)
Whole population 0.09 0.11 0.07
Only index persons 0.11 0.13 0.09
Median age at first event (years)
Whole population 71.27 74.94 66.17
Only index persons 71.43 75.09 66.04

-FinnGen-

Key figures

All Female Male
Number of individuals 908 486 422
Unadjusted period prevalence (%) 0.18 0.17 0.19
Median age at first event (years) 69.54 69.58 69.50

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
940
Matched controls
9400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
15.4
308.8
317
300
H43.1
ICD-10 Finland
Vitreous haemorrhage
75.1
307.7
187
31
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
640.4
307.7
336
8
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
307.7
915
*
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
652.1
297.2
279
6
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
57.8
292.8
167
35
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
101.8
268.0
139
16
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
18.6
266.2
232
163
CKC12
NOMESCO Finland
Photocoagulation of retina
138.2
261.1
131
11
XCW99
NOMESCO Finland
Other investigative procedure of eye
11.4
235.5
294
362
WX140
NOMESCO Finland
Parabulbar anesthesy
22.2
232.4
181
100
XCK10
NOMESCO Finland
Photography of fundus of eye
8.9
171.1
252
373
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
1411.9
129.3
123
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
27.8
104.8
72
28
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.5
90.3
292
864
XCD20
NOMESCO Finland
Photoangiography of eye
114.5
86.7
93
9
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.4
86.1
278
819
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
26.2
84.2
59
24
H33.0
ICD-10 Finland
Retinal detachment with retinal break
883.6
83.9
81
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
136.8
82.5
87
7
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
287.4
78.8
79
*
A10AA01, ,
ATC
17.2
78.6
66
41
A10AB01
ATC
insulin (human); parenteral
12.1
76.1
79
71
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
36.3
71.5
45
13
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
21.5
67.5
51
25
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
67.5
64
*
A10AA02, ,
ATC
10.4
66.2
76
79
CKC10
NOMESCO Finland
Local photocoagulation of retina
340.4
63.2
63
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.1
61.7
485
2432
T89
ICPC
Diabetes insulin dependent
9.1
61.3
78
93
XCH00
NOMESCO Finland
Eye pressure measurement
6.6
59.9
103
173
H34.8
ICD-10 Finland
Other retinal vascular occlusions
213.3
58.8
60
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
8.6
55.7
74
93
H43.8
ICD-10 Finland
Other disorders of vitreous body
4.4
55.6
158
413
A10AC01
ATC
insulin (human); parenteral
4.9
55.2
135
313
H3603, E103,
ICD-10 Finland
+∞
54.7
52
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.3
54.6
160
428
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.8
53.1
476
2505
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
547.5
53.0
52
*
H26.4
ICD-10 Finland
After-cataract
3.9
51.1
177
533
A10AB04
ATC
insulin lispro; parenteral
8.8
50.2
65
79
A10AB05
ATC
insulin aspart; parenteral
4.6
50.1
129
311
H33.3
ICD-10 Finland
Retinal breaks without detachment
502.8
48.8
48
*
H04AA01
ATC
glucagon; nasal, parenteral
13.5
46.3
44
34
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
43.0
41
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
436.5
42.5
42
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
425.5
41.5
41
*
H36.01
ICD-10 Finland
Diabetic maculopathy
219.5
41.2
42
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
7.6
39.4
57
79
H3603, E113,
ICD-10 Finland
+∞
37.8
36
*
A10AE04
ATC
insulin glargine; parenteral
3.5
36.9
140
443
XCD10
NOMESCO Finland
Electrophysiological examination of eye
7.0
36.5
57
86
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
371.0
36.2
36
*
XCK00
NOMESCO Finland
Perimetry
4.3
36.1
101
258
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
35.6
34
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
360.1
35.2
35
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
14.4
34.9
32
23
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
96.2
34.0
37
*
ZXA10
NOMESCO Finland
Bilateral
2.6
33.0
242
1104
A10AE05
ATC
insulin detemir; parenteral
4.4
30.9
82
201
H53.1
ICD-10 Finland
Subjective visual disturbances
3.8
30.2
98
278
H53.4
ICD-10 Finland
Visual field defects
6.7
29.2
47
73
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
82.8
28.9
32
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
154.8
28.8
30
*
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
56.9
28.3
33
6
A10AE06
ATC
insulin degludec; parenteral
5.6
27.9
54
101
127
Kela drug reimbursment
Transplant complication
10.0
27.8
32
33
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
26.3
27.7
38
15
CKC15
NOMESCO Finland
Panretinal photocoagulation
77.5
26.9
30
*
S01ED51
ATC
timolol, combinations; ophthalmic
3.2
26.9
117
401
H3600, E113,
ICD-10 Finland
+∞
26.2
25
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
26.0
119
420
H3600, E103,
ICD-10 Finland
+∞
25.1
24
*
H3601, E103,
ICD-10 Finland
+∞
25.1
24
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
40.0
25.0
31
8
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.7
24.1
57
127
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
128.3
23.7
25
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.7
23.6
56
125
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
23.6
455
3001
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.6
23.5
81
239
WX142
NOMESCO Finland
Sub-tenon anesthesy
37.3
23.1
29
8
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
+∞
23.0
22
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
23.0
22
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
23.0
22
*
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
6.1
22.8
40
68
H25.8
ICD-10 Finland
Other senile cataract
2.6
22.7
154
667
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
22.2
269
1493
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
22.0
21
*
ZX198
NOMESCO Finland
Other local administration
25.8
21.8
30
12
H25.1
ICD-10 Finland
Senile nuclear cataract
2.0
21.4
348
2144
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
21.3
21.4
31
15
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
20.9
20
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.5
20.9
30
41
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
78.6
20.8
23
*
H3601, E113,
ICD-10 Finland
+∞
19.9
19
*
1LA05, ,
NOMESCO Finland
+∞
19.9
19
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
25.2
19.6
27
11
A10AD01
ATC
insulin (human); parenteral
6.6
19.3
31
48
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
19.0
294
1767
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
18.8
18
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.2
18.2
38
76
C08CA01
ATC
amlodipine; oral
1.8
18.0
427
2935
H33.5
ICD-10 Finland
Other retinal detachments
27.3
17.9
24
9
TK800
NOMESCO Finland
Hemodialysis
5.4
17.6
35
67
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
14.2
17.4
29
21
AA1AD
NOMESCO Finland
CT of head and brain
1.9
17.1
308
1935
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
16.3
17.1
27
17
ZXA05
NOMESCO Finland
Left side
1.9
17.1
271
1634
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.7
16.9
54
151
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.3
16.8
150
730
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
+∞
16.7
16
*
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
16.7
16
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
16.5
478
3456
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.1
16.5
35
71
S01EC01
ATC
acetazolamide; systemic
5.0
16.5
36
75
H35.9
ICD-10 Finland
Retinal disorder, unspecified
40.9
16.4
20
5
C03CA01
ATC
furosemide; systemic
1.8
16.2
381
2589
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
16.1
633
4991
S01BC03
ATC
diclofenac; ophthalmic
5.1
15.8
33
66
H35.4
ICD-10 Finland
Peripheral retinal degeneration
86.6
15.6
17
*
ZXD05
NOMESCO Finland
Urgent procedure
1.8
15.5
303
1941
H35.37
ICD-10 Finland
Macular holes
162.6
15.5
16
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
38.8
15.4
19
5
B03XA02
ATC
darbepoetin alfa; parenteral
4.6
15.1
36
81
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.8
15.0
78
294
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
14.9
254
1556
A11CC03
ATC
alfacalcidol; systemic
4.4
14.7
37
87
WX002
NOMESCO Finland
Sedation and analgesia
2.0
14.5
202
1157
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
152.3
14.5
15
*
L04AA06
ATC
mycophenolic acid; systemic
6.1
14.4
25
42
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.6
14.3
24
18
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
22.7
14.3
20
9
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
4.9
14.1
31
65
177
Kela drug reimbursment
Insulin glargine 300 U / ml
5.5
14.1
27
50
S01EA05
ATC
brimonidine; ophthalmic
3.8
13.8
42
114
WW200
NOMESCO Finland
Immunization
4.3
13.7
35
83
37701
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia retinae et chorioideae
+∞
13.6
13
*
Z49.2
ICD-10 Finland
Other dialysis
16.5
13.5
21
13
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
18.5
13.4
20
11
H26.2
ICD-10 Finland
Complicated cataract
14.0
13.3
22
16
ZXA00
NOMESCO Finland
Right side
1.8
13.1
275
1784
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
28.8
13.0
17
6
137
Kela drug reimbursment
Uraemia requiring dialysis
13.2
13.0
22
17
C02AC05
ATC
moxonidine; oral
2.8
12.9
67
252
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
22.9
12.9
18
8
WZC30
NOMESCO Finland
Teaching
2.0
12.8
156
850
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.8
12.7
64
237
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
12.5
12
*
3628A
ICD-9 Finland
Other retinal disorders[HAEMORRHAGIA RETINAE]
+∞
12.5
12
*
V03AE02
ATC
sevelamer; oral
24.7
12.5
17
7
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
24.7
12.5
17
7
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
131.7
12.5
13
*
S01BC05
ATC
ketorolac; ophthalmic
2.9
12.4
58
206
F29
ICPC
Eye symptom/complaint other
2.3
11.9
97
453
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
11.5
137
740
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
+∞
11.5
11
*
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
11.5
11
*
A12AA04
ATC
calcium carbonate; oral
4.9
11.5
25
52
N02BE01
ATC
paracetamol; systemic, rectal
2.0
11.4
824
7321
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
11.4
272
1818
H16.0
ICD-10 Finland
Corneal ulcer
2.9
11.2
54
195
V03AE01
ATC
polystyrene sulfonate; oral
5.6
11.2
21
38
B05DA
ATC
Isotonic solutions
12.9
11.2
19
15
A10AA03, ,
ATC
9.4
11.0
22
24
S18
ICPC
Laceration/cut
1.6
10.9
427
3224
C07AB07
ATC
bisoprolol; oral
1.6
10.8
499
3914
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
18.1
10.7
16
9
H25.0
ICD-10 Finland
Senile incipient cataract
2.4
10.7
75
327
L04AD01
ATC
ciclosporin; systemic
5.3
10.6
21
40
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
111.2
10.4
11
*
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
10.4
10
*
H3602, E103,
ICD-10 Finland
+∞
10.4
10
*
H35.36
ICD-10 Finland
Macular cyst
+∞
10.4
10
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.5
10.4
20
37
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
4.0
10.4
29
74
T90
ICPC
Diabetes non-insulin dependent
1.7
10.3
229
1495
Z94.0
ICD-10 Finland
Kidney transplant status
10.7
10.3
19
18
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
19.0
10.3
15
8
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.0
330
2380
J01DB01
ATC
cefalexin; oral
1.7
9.9
729
6324
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
9.8
119
645
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
55.6
9.7
11
*
XCW10
NOMESCO Finland
Assessment of vision
7.9
9.6
21
27
C09CA01
ATC
losartan; oral
1.6
9.6
256
1752
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.5
9.5
32
93
SPAT1263
SPAT
Sampling
1.6
9.5
375
2809
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
9.5
236
1583
H34.2
ICD-10 Finland
Other retinal artery occlusions
101.0
9.4
10
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
101.0
9.4
10
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
9.4
9
*
A98
ICPC
Health maint/preventive medicine
2.1
9.4
865
7928
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
12.5
9.4
16
13
S01EE01
ATC
latanoprost; ophthalmic
2.2
9.4
76
354
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
9.3
171
1056
H57.1
ICD-10 Finland
Ocular pain
3.0
9.3
40
136
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
4.1
9.3
25
62
J01MA02
ATC
ciprofloxacin; systemic
1.5
9.2
362
2706
A02BC02
ATC
pantoprazole; systemic
1.6
9.1
617
5184
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
11.6
9.1
16
14
L04AD02
ATC
tacrolimus; systemic
10.2
9.0
17
17
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
9.0
41
144
SPAT1262
SPAT
Handing over of treatment supplies
1.7
9.0
167
1036
B05DB
ATC
Hypertonic solutions
12.7
8.9
15
12
L17
ICPC
Foot/toe symptom/complaint
1.6
8.8
260
1815
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
8.7
102
547
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
50.5
8.7
10
*
205
Kela drug reimbursment
Chronic hypertension
1.6
8.6
291
2096
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
11.7
8.6
15
13
J01MA12
ATC
levofloxacin; systemic
1.7
8.4
180
1159
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
12.9
8.4
14
11
H3603, E107,
ICD-10 Finland
+∞
8.3
8
*
CKD90
NOMESCO Finland
Removal of subretinal haematoma
+∞
8.3
8
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
8.3
8
*
H40.0
ICD-10 Finland
Glaucoma suspect
2.1
8.3
77
378
C09AA02
ATC
enalapril; systemic
1.6
8.3
205
1369
L28
ICPC
Limited function/disability (L)
1.7
8.3
189
1237
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
8.3
82
414
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
8.2
338
2538
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.4
8.1
53
224
SPAT1325
SPAT
Vaccination
1.5
8.1
325
2426
R42
ICD-10 Finland
Dizziness and giddiness
1.6
8.0
221
1514
J01FF01
ATC
clindamycin; systemic
1.6
8.0
236
1644
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
8.0
336
2532
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.7
8.0
43
166
C08CA13
ATC
lercanidipine; oral
1.7
7.9
152
949
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
4.7
7.9
18
39
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
7.9
583
4913
C10AA05
ATC
atorvastatin; oral
1.5
7.9
394
3073
H44.1
ICD-10 Finland
Other endophthalmitis
45.4
7.7
9
*
H44.0
ICD-10 Finland
Purulent endophthalmitis
45.4
7.7
9
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.0
7.7
20
34
H53.8
ICD-10 Finland
Other visual disturbances
4.4
7.7
19
44
Z49.0
ICD-10 Finland
Preparatory care for dialysis
7.5
7.7
17
23
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
4.6
7.7
18
40
C02CA01
ATC
prazosin; oral
3.6
7.6
24
67
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
7.6
197
1330
S01BA07
ATC
fluorometholone; ophthalmic
4.5
7.4
18
41
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
7.4
86
460
Z3231
NOMESCO Finland
Registered nurse
1.5
7.4
244
1741
R04.0
ICD-10 Finland
Epistaxis
2.0
7.3
83
440
H44.2
ICD-10 Finland
Degenerative myopia
+∞
7.3
7
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.2
7.2
27
85
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
20.2
7.1
10
5
J01CF05
ATC
flucloxacillin; systemic
2.2
7.1
57
265
XKD00
NOMESCO Finland
Uroflowmetry
1.7
7.1
146
929
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
7.0
266
1951
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
7.0
168
1111
F16
ICPC
Eyelid symptom/complaint
2.4
7.0
46
196
WX199
NOMESCO Finland
Other local analgesia
2.7
7.0
36
136
SPAT1310
SPAT
Counselling related to known health issue
1.5
6.9
273
2017
SPAT1229
SPAT
Assessment of need for aid
1.9
6.9
85
464
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
6.9
159
1042
H20.1
ICD-10 Finland
Chronic iridocyclitis
9.4
6.8
13
14
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
6.2
6.8
17
28
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.2
6.8
17
28
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.6
6.8
37
144
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
40.3
6.8
8
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
6.7
57
272
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.8
6.7
33
122
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
6.7
103
604
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.7
6.6
126
785
H54.7
ICD-10 Finland
Unspecified visual loss
8.8
6.6
13
15
R51.80
ICD-10 Finland
Headache
1.7
6.6
124
770
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.1
6.5
12
12
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
10.1
6.5
12
12
SPAT1312
SPAT
General health counselling
1.5
6.5
255
1877
B01AC04
ATC
clopidogrel; oral
1.6
6.5
171
1154
Z2446
NOMESCO Finland
Social worker
2.1
6.4
61
303
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
6.4
378
3007
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
14.4
6.4
10
7
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
4.1
6.4
17
42
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
6.4
229
1657
Z01.2
ICD-10 Finland
Dental examination
1.4
6.3
336
2626
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
6.3
158
1056
H02AB06
ATC
prednisolone; systemic
1.4
6.3
415
3369
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
6.3
6
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
6.3
6
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
5.8
6.2
16
28
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.1
340
2671
H54.5
ICD-10 Finland
Severe visual impairment, monocular
8.7
6.1
12
14
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
6.1
240
1769
CHC05
NOMESCO Finland
Iridotomy
3.5
6.0
20
58
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
3.5
6.0
20
58
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
6.0
54
263
S01EA03
ATC
apraclonidine; ophthalmic
6.1
6.0
15
25
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
3.9
6.0
17
44
R05
ICPC
Cough
1.5
6.0
198
1405

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
624
4529
2.12
25.56
8.1
4.8
7.42
6.75
mmol/l
6.32
594
4266
553
3981
1.95
21.41
11.5
6.6
1.21
1.21
mmol/l
1.98
457
3360
529
3791
1.90
20.33
23.4
17.2
1.35
1.31
inr
0.37
150
1064
353
2265
1.89
18.68
4.1
3.1
243.17
289.26
mg/l
0.11
226
1441
45
102
4.58
18.64
1.8
1.3
102.08
110.00
u/ml
0.26
13
16
360
2369
1.84
17.28
4.1
3.0
6.51
7.27
mmol/l
2.83
285
1974
361
2399
1.82
16.63
4.7
3.6
22.84
8.39
mg/mmol
2.72
231
1495
29
49
6.07
16.59
1.3
1.2
—
—
—
0
0
377
2556
1.79
16.12
3.5
3.2
1996.41
1668.46
ng/l
0.56
332
2208
44
110
4.15
16.10
1.8
1.3
—
—
—
0
0
497
3663
1.76
15.81
11.6
5.9
1.21
1.21
mmol/l
1.32
446
3314
215
1230
1.97
15.63
2.7
1.9
29.87
29.86
s
0.01
208
1192
29
53
5.61
15.32
2.6
2.4
—
—
—
0
0
192
1071
2.00
14.94
12.0
5.0
1.15
1.02
mmol/l
5.82
183
974
707
5836
1.85
14.64
11.0
7.3
85.23
79.10
u/l
1.79
670
5454
467
3440
1.71
14.39
8.8
5.7
—
—
—
0
0
860
7635
2.49
14.19
29.1
18.6
139.28
139.60
mmol/l
2.76
845
7419
861
7653
2.49
14.07
29.7
18.7
4.02
3.99
mmol/l
2.76
843
7425
837
7367
2.24
13.74
23.9
15.6
25.60
26.19
mg/l
0.19
701
5912
485
3657
1.67
13.32
7.1
5.3
0.62
0.59
e9/l
1.81
433
3129
486
3667
1.67
13.30
7.1
5.3
0.04
0.04
e9/l
0.16
434
3146
498
3787
1.67
13.18
7.8
5.6
0.19
0.19
e9/l
0.15
446
3300
347
2404
1.70
13.07
2.5
2.1
264.89
238.74
u/l
0.10
324
2261
643
5237
1.72
13.05
5.3
4.6
—
—
—
0
0
492
3736
1.66
13.05
7.3
5.4
2.06
1.85
e9/l
0.57
448
3273
306
2050
1.73
13.02
2.8
2.2
2.90
3.10
mg/l
0.80
264
1714
135
705
2.07
12.47
15.9
6.4
11.89
10.37
mmol/l
1.72
127
662
332
2309
1.68
12.13
5.9
4.2
—
—
—
0
0
206
1253
1.82
12.09
4.2
2.4
12.68
12.39
umol/l
0.22
191
1156
421
3115
1.64
12.04
4.8
3.9
48.38
56.83
ng/l
0.27
332
2305
248
1598
1.75
11.96
2.0
1.7
1.29
1.26
mg/l
0.03
199
1241
665
5524
1.70
11.93
4.9
4.0
15.96
13.63
mm/h
2.85
613
5044
411
3042
1.62
11.61
4.1
2.7
166.79
134.50
ug/l
0.79
375
2751
129
680
2.04
11.59
13.2
8.1
—
—
—
0
0
443
3345
1.61
11.49
2.2
2.1
92.20
94.40
pmol/l
0.44
228
1678
860
7763
2.27
11.43
15.2
10.5
24.33
25.28
u/l
1.22
823
7445
542
4302
1.61
11.39
11.6
8.7
4.49
4.13
e9/l
2.05
497
3756
205
1266
1.79
11.38
5.6
3.1
0.82
0.81
mmol/l
0.66
193
1175
190
1148
1.82
11.33
4.2
2.4
2.23
2.30
g/l
0.93
177
1050
452
3447
1.60
11.13
8.5
5.9
8.64
8.73
%
0.20
433
3205
338
2404
1.63
11.09
4.2
3.4
43.13
98.24
e6/l
1.09
281
1880
380
2782
1.61
11.08
4.8
3.9
131.73
118.52
e6/l
0.08
291
2014
37
107
3.56
11.08
1.7
1.2
254.34
285.83
u/ml
0.23
29
59
23
46
5.10
11.04
1.2
1.3
—
—
—
0
0
458
3509
1.60
11.02
8.3
5.7
26.17
26.95
%
0.65
439
3272
140
774
1.95
10.97
7.4
3.4
1.82
2.20
mmol/l
0.52
123
639
779
6833
1.82
10.72
8.2
5.9
43.63
40.04
mmol/mol
12.06
698
6259
340
2438
1.62
10.71
4.2
2.4
—
—
—
0
0
181
1096
1.81
10.67
4.4
2.4
23.10
21.85
%
0.53
157
927
768
6721
1.78
10.49
5.6
4.7
1.97
2.19
mu/l
0.60
689
6051
880
8067
2.42
10.46
35.5
23.0
38.94
39.60
%
2.10
837
7449
619
5127
1.61
10.44
5.8
4.9
3.67
2966.79
e6/l
—
6
82
287
1986
1.64
10.38
3.9
2.7
3046.11
7104.53
umol/l
1.12
243
1700
447
3439
1.57
10.34
8.1
5.5
2.81
2.85
%
0.12
427
3196
133
737
1.94
10.33
2.8
2.5
6.14
6.57
ug/l
0.14
119
632
803
7137
1.86
10.20
5.4
4.5
4.34
4.57
mmol/l
8.04
722
6512
29
75
3.96
10.18
1.4
1.1
—
—
—
0
0
879
8069
2.38
10.15
34.9
22.9
239.28
245.55
e9/l
1.85
864
7834
879
8070
2.37
10.13
34.8
22.9
91.31
91.38
fl
0.16
871
7917
509
4045
1.56
10.13
9.1
6.0
11.23
11.96
umol/l
0.64
477
3851
879
8071
2.37
10.11
34.8
22.8
30.24
30.36
pg
1.06
871
7918
879
8072
2.37
10.09
34.9
22.9
7.12
6.79
e9/l
1.71
856
7813
879
8072
2.37
10.09
35.0
22.9
4.35
4.42
e12/l
3.01
861
7813
74
330
2.35
10.07
9.7
4.6
—
—
—
0
0
436
3350
1.56
10.05
8.1
5.5
0.63
0.65
%
0.24
415
3111
879
8074
2.37
10.05
35.2
23.1
130.50
133.40
g/l
6.16
871
7918
816
7306
1.89
9.89
6.0
5.0
2.48
2.67
mmol/l
7.66
730
6612
103
532
2.05
9.75
3.4
2.7
9.94
10.79
g/l
1.05
91
472
251
1703
1.65
9.71
3.4
2.6
5.06
5.88
e6/l
0.28
223
1545
328
2378
1.58
9.65
8.3
3.9
7.39
7.40
ph
0.52
67
459
310
2227
1.58
9.44
4.2
3.3
0.56
0.52
e6/l
0.11
255
1724
244
1655
1.64
9.42
1.8
1.8
1218.99
1200.88
nmol/l
0.10
184
1219
443
3452
1.54
9.36
7.7
5.4
58.56
57.73
%
0.65
419
3219
352
2610
1.56
9.31
3.5
3.4
—
—
—
0
0
161
981
1.77
9.21
4.3
2.3
1.83
1.79
%
0.16
143
875
176
1104
1.73
9.09
2.9
2.0
—
—
—
0
0
16
14
11.60
9.08
1.0
1.0
—
—
—
0
0
266
1857
1.60
9.08
3.8
2.3
—
—
—
0
0
85
425
2.10
8.77
2.7
1.7
2.00
1.53
g/l
0.31
70
377
440
3458
1.51
8.73
7.2
4.6
34.59
34.97
g/l
0.74
406
3188
47
184
2.64
8.45
2.7
2.2
75.17
91.33
ug/min
0.19
30
108
206
1373
1.64
8.42
3.0
2.9
1.00
1.14
e6/l
0.28
131
815
394
3046
1.51
8.35
2.9
2.2
81.13
78.42
nmol/l
0.93
349
2666
58
253
2.38
8.32
3.3
2.1
20.80
21.63
s
0.69
51
230
15
14
10.87
8.31
1.0
1.1
—
—
—
0
0
789
7083
1.71
8.30
5.4
4.4
1.41
1.46
mmol/l
2.23
704
6418
460
3675
1.49
8.27
4.9
3.9
0.00
0.00
estimate
0.50
87
675
767
6838
1.66
8.25
4.9
4.0
1.31
1.29
mmol/l
0.45
676
6146
146
894
1.75
8.17
2.3
1.6
—
—
—
0
0
78
389
2.10
8.11
8.7
3.5
23.74
24.44
mmol/l
0.93
78
379
381
2939
1.50
8.09
4.3
3.6
5.77
5.82
ph
0.10
13
177
293
2141
1.54
8.03
4.3
3.3
—
—
—
0
0
455
3642
1.48
8.02
6.1
5.3
0.00
0.00
estimate
-0.00
87
688
29
89
3.33
7.98
1.7
1.3
—
—
—
0
0
456
3661
1.48
7.86
4.9
3.9
0.00
0.00
estimate
0.74
92
743
113
648
1.85
7.86
4.9
3.5
116.74
88.57
ng/l
1.30
98
554
124
734
1.79
7.78
4.7
2.3
70.86
67.39
e9/l
0.39
106
576
132
796
1.77
7.77
6.1
4.4
—
—
—
0
0
41
160
2.63
7.44
1.6
1.2
—
—
—
0
0
371
2883
1.47
7.42
2.0
2.2
—
—
—
0
0
642
5550
1.49
7.38
4.4
3.9
15.20
14.98
pmol/l
1.37
564
4961
272
1997
1.51
7.16
5.7
4.1
0.00
0.01
estimate
0.69
80
658
230
1630
1.54
7.13
3.9
3.0
514.16
541.97
mosm/kgh2o
1.25
195
1402
437
3536
1.44
6.93
4.1
2.6
—
—
—
0
0
192
1314
1.58
6.92
1.6
1.5
2.61
2.56
g/l
0.04
116
742
93
522
1.87
6.92
4.2
3.8
7.41
7.40
ph
—
9
68
788
7158
1.62
6.89
5.5
4.7
6.39
5.98
mmol/l
7.13
694
6421
273
2019
1.50
6.89
1.6
1.6
20.23
20.61
nmol/l
0.16
226
1692
110
651
1.78
6.89
2.2
1.5
—
—
—
0
0
222
1572
1.54
6.88
5.0
4.0
194.33
332.55
ng/l
0.84
183
1308
117
708
1.75
6.79
3.6
2.9
65.98
66.02
g/l
0.02
101
642
306
2324
1.47
6.74
4.2
4.2
—
—
—
0
0
77
411
1.95
6.66
2.1
1.7
1.37
1.57
g/l
1.28
64
360
90
508
1.85
6.58
4.7
3.0
125.09
128.13
g/l
0.69
90
497
136
866
1.67
6.55
2.1
1.4
—
—
—
0
0
241
1760
1.50
6.41
4.8
3.8
—
—
—
0
0
823
7594
1.67
6.33
21.8
14.9
—
—
—
0
0
29
103
2.87
6.30
1.2
1.1
—
—
—
0
0
11
10
11.11
6.30
1.5
1.0
—
—
—
0
0
351
2765
1.43
6.27
3.5
3.3
2.35
2.36
mmol/l
0.29
301
2392
310
2393
1.44
6.16
4.4
2.4
60.48
94.82
u/l
0.51
279
2204
100
599
1.75
6.02
3.3
2.6
—
—
—
0
0
106
648
1.72
5.93
2.2
1.9
381.53
376.75
nmol/l
0.08
97
584
13
19
6.92
5.75
2.2
1.3
—
—
—
0
0
182
1283
1.52
5.67
3.3
3.1
2.78
2.27
e6/l
0.32
112
735
47
222
2.18
5.67
1.5
1.5
272.59
276.87
ug/g
0.05
32
130
116
739
1.65
5.57
2.2
1.5
—
—
—
0
0
136
911
1.58
5.32
1.3
1.3
603.33
487.57
titre
0.28
36
185
140
947
1.56
5.24
11.2
7.4
5.07
5.11
kpa
0.20
134
902
140
948
1.56
5.22
11.2
7.4
11.24
11.84
kpa
0.94
134
906
20
64
3.17
5.21
1.1
1.2
—
—
—
0
0
134
901
1.57
5.15
2.2
1.7
—
—
—
0
0
12
19
6.38
5.09
1.0
1.1
1807.33
1557.47
miu/ml
0.31
12
19
59
321
1.89
4.88
1.3
1.3
—
12.36
—
0
5
138
950
1.53
4.77
11.4
7.4
1.10
1.31
mmol/l
0.30
112
734
390
3235
1.35
4.76
14.1
9.7
0.03
0.00
e9/l
0.60
329
2649
244
1882
1.40
4.67
1.8
1.6
1.31
1.35
mmol/l
0.31
199
1582
31
135
2.34
4.56
1.2
1.2
83.64
49.91
u/l
0.46
25
120
26
106
2.49
4.41
1.2
1.1
—
—
—
0
0
32
144
2.27
4.38
3.3
1.4
—
—
—
0
0
9
12
7.56
4.36
5.0
3.5
—
—
—
0
0
69
409
1.74
4.35
1.7
1.4
—
—
—
0
0
33
156
2.16
4.04
4.0
2.5
—
—
—
0
0
85
551
1.60
3.84
6.5
3.8
0.95
0.60
%
0.66
42
186
6
5
12.06
3.76
2.2
1.4
—
—
—
0
0
92
611
1.56
3.75
6.3
3.9
1.27
0.95
%
0.36
44
220
22
90
2.48
3.74
1.2
1.2
2.75
8.21
u/ml
1.03
12
43
35
175
2.04
3.73
3.5
2.4
—
—
—
0
0
64
389
1.69
3.72
3.8
4.0
—
—
—
0
0
28
129
2.21
3.67
2.0
1.5
—
—
—
0
0
9
16
5.67
3.66
2.2
1.4
—
—
—
0
0
589
5298
1.30
3.64
5.2
4.1
—
—
—
0
0
189
1455
1.37
3.59
1.3
1.3
0.70
1.85
u/ml
2.16
54
363
86
569
1.56
3.57
7.4
4.6
—
—
—
0
0
29
138
2.14
3.52
13.9
2.7
—
—
—
0
0
15
52
2.92
3.47
1.9
1.7
39.81
37.84
%
0.19
15
52
517
4590
1.28
3.45
3.8
3.1
57.34
49.54
u/l
0.93
465
4233
123
885
1.45
3.43
6.1
2.7
10.22
8.96
umol/l
0.19
108
767
97
668
1.50
3.37
4.7
3.4
—
—
—
0
0
98
678
1.50
3.33
1.6
1.4
—
—
—
0
0
234
1882
1.32
3.31
9.9
6.7
—
—
—
0
0
101
705
1.48
3.29
4.2
2.4
34.38
101.17
u/l
0.49
85
602
154
1166
1.38
3.23
1.3
1.3
30.64
38.28
iu/ml
0.38
33
375
22
97
2.30
3.21
2.7
2.0
213.41
4389.62
u/l
—
9
29
10
24
4.20
3.20
1.4
1.2
—
—
—
0
0
49
290
1.73
3.17
2.8
2.1
5034.28
475.02
ug/l
0.48
49
275
20
86
2.35
3.09
4.8
2.1
1.74
1.26
g/24h
0.47
13
36
201
1599
1.33
3.05
3.1
3.1
2.46
2.46
mmol/l
0.06
181
1389
5
5
10.04
2.98
1.4
1.0
—
—
—
0
0
30
155
1.97
2.97
1.5
1.5
—
—
—
0
0
107
773
1.43
2.94
3.3
3.0
193.16
227.55
ng/l
0.77
99
720
41
236
1.77
2.93
1.3
1.2
1.06
1.93
u/ml
—
9
15
23
108
2.16
2.92
1.5
1.2
—
—
—
0
0
52
321
1.66
2.90
4.5
2.8
10.95
10.30
g/l
0.32
44
285
11
32
3.47
2.90
1.0
1.0
—
—
—
0
0
213
1720
1.31
2.90
1.9
1.7
79375429.61
8129934.27
pmol/l
0.43
160
1390
32
171
1.90
2.89
6.4
4.1
—
—
—
0
0
23
109
2.14
2.86
1.3
1.5
—
—
—
0
0
83
576
1.48
2.81
6.0
4.0
0.14
0.13
%
0.06
36
183
9
23
3.94
2.78
2.1
1.5
—
—
—
0
0
54
341
1.62
2.77
2.3
1.9
2.41
1.40
ug/l
0.51
48
304
51
318
1.64
2.75
1.1
1.2
—
—
—
0
0
63
414
1.56
2.74
2.6
2.6
0.32
0.40
e6/l
0.21
63
402
27
139
1.97
2.72
6.4
3.3
57.96
58.35
%
0.04
27
139
12
40
3.03
2.70
6.4
11.9
—
—
—
0
0
35
198
1.80
2.67
2.2
1.6
18390.46
16923.88
e6/l
0.05
26
142
94
677
1.43
2.64
10.5
3.9
1.23
1.23
mmol/l
0.00
80
590
38
223
1.73
2.57
7.7
4.3
7.42
7.41
ph
0.14
33
198
38
223
1.73
2.57
1.5
1.7
—
—
—
0
0
11
36
3.08
2.57
2.4
2.1
22.26
20.41
nmol/l
0.11
11
31
12
44
2.75
2.55
1.6
3.0
37.00
38.40
%
—
6
23
10
31
3.25
2.52
1.0
1.0
—
—
—
0
0
47
297
1.61
2.43
4.0
3.4
0.43
0.24
g/l
1.11
23
121
100
742
1.39
2.39
2.7
2.1
0.21
0.21
g/l
0.13
95
684
87
630
1.42
2.39
5.5
3.9
—
—
—
0
0
10
33
3.05
2.36
2.3
1.9
6611.10
1299.30
u/ml
—
10
33
121
928
1.35
2.36
1.2
1.3
—
—
—
0
0
45
287
1.60
2.26
3.7
3.7
54.55
274.14
mg/l
0.57
36
233
31
179
1.76
2.25
7.8
4.8
2.21
2.64
mmol/l
0.40
22
118
5
9
5.58
2.21
7.0
13.9
7.52
5.94
mmol/l
—
5
9
271
2324
1.23
2.20
4.5
3.3
32.72
33.48
u/l
0.15
252
2208
76
546
1.43
2.19
6.7
3.9
0.68
0.66
%
0.01
31
155
8
24
3.35
2.18
3.5
1.2
—
—
—
0
0
30
174
1.75
2.15
1.1
1.1
281.67
62.31
titre
—
6
13
25
137
1.85
2.15
2.6
1.2
—
—
—
0
0
28
160
1.77
2.11
1.3
1.3
83.62
61.26
mmol/l
0.99
21
130
43
277
1.58
2.09
4.9
2.7
37.79
37.31
g/l
0.19
35
242
17
82
2.09
2.07
1.2
1.2
—
—
—
0
0
38
238
1.62
2.07
1.3
1.1
—
—
—
0
0
9
31
2.92
2.07
1.3
1.4
119.67
172.09
mmol/24h
—
9
31
5
10
5.02
2.07
2.4
1.4
188.74
93.60
ng/l
—
5
10
39
246
1.61
2.07
28.1
10.4
—
—
—
0
0
44
287
1.56
2.04
3.8
3.7
34.23
40.91
mg/l
0.38
35
233
48
321
1.52
2.00
1.6
2.1
—
—
—
0
0
664
6245
1.22
2.00
26.6
18.7
15.77
15.19
%
1.43
653
6129
29
172
1.71
1.95
1.9
1.3
23.67
31.67
iu/l
0.65
24
141
14
64
2.21
1.95
2.3
2.0
9.19
11.17
%
0.84
14
64
15
71
2.13
1.93
1.5
1.6
—
—
—
0
0
217
1843
1.23
1.91
1.4
1.3
—
—
—
0
0
17
85
2.02
1.91
1.1
1.3
—
—
—
0
0
17
85
2.02
1.91
2.6
2.2
—
—
—
0
0
141
1140
1.28
1.90
1.2
1.3
7.65
12.94
u/ml
0.45
45
407
28
166
1.71
1.89
1.3
1.2
4.26
12.32
u/ml
—
8
28
8
28
2.87
1.86
3.8
3.9
—
—
—
0
0
36
230
1.59
1.84
3.3
3.3
—
—
—
0
0
19
101
1.90
1.81
1.4
1.8
0.66
0.87
g/l
0.38
11
77
23
131
1.77
1.79
1.2
1.4
170.80
249.29
miu/ml
—
5
59
99
772
1.32
1.76
2.1
2.0
159.96
132.61
ug/g
0.23
73
614
6
18
3.35
1.75
1.2
1.4
—
—
—
0
0
17
89
1.93
1.70
1.1
1.3
0.55
0.65
nmol/l
0.98
17
83
10
40
2.52
1.67
1.9
2.2
0.31
0.24
e9/l
—
10
35
27
165
1.66
1.66
1.3
1.2
2.55
2.88
u/ml
—
6
20
195
1662
1.22
1.66
5.9
4.2
1.01
1.02
kg/l
0.74
24
239
26
158
1.66
1.63
2.7
1.2
5.45
32.13
e6/l
0.73
20
126
284
2515
1.19
1.60
5.2
5.1
2.31
2.60
ug/l
0.31
252
2228
127
1038
1.26
1.59
1.3
1.2
—
—
—
0
0
22
129
1.72
1.57
1.4
1.4
—
—
—
0
0
7
27
2.60
1.51
1.1
2.0
1.37
0.97
nmol/l
—
7
21
5
16
3.14
1.44
1.4
1.8
83.60
110.25
nmol/24h
—
5
16
5
16
3.14
1.44
36.6
6.8
—
—
—
0
0
13
66
1.98
1.44
1.5
1.3
5.66
7.30
g/l
—
7
47
13
66
1.98
1.44
1.5
1.3
0.23
0.41
g/l
—
7
47
13
66
1.98
1.44
1.5
1.3
2.35
2.64
g/l
—
7
48
99
796
1.27
1.43
1.3
1.3
—
—
—
0
0
16
88
1.83
1.42
8.8
4.3
—
—
—
0
0
13
67
1.95
1.38
1.5
1.3
—
—
—
0
0
61
461
1.35
1.38
2.9
3.3
6.12
6.22
e9/l
0.02
42
351
12
60
2.01
1.38
2.2
1.1
—
—
—
0
0
9
41
2.21
1.37
2.0
2.2
446.89
660.86
e6/l
—
9
35
52
384
1.37
1.36
1.4
1.2
—
—
—
0
0
17
97
1.77
1.35
1.6
1.5
51.75
66.69
%
0.72
12
61
35
241
1.47
1.34
2.1
1.3
1.19
1.21
g/l
0.17
35
229
31
209
1.50
1.31
3.3
3.8
—
—
—
0
0
34
234
1.47
1.31
2.0
1.4
0.23
0.24
g/l
0.33
34
224
32
460
0.68
1.31
1.4
1.3
—
—
—
0
0
5
18
2.79
1.28
1.2
1.2
—
—
—
0
0
10
48
2.09
1.28
2.8
2.5
—
—
—
0
0
26
170
1.54
1.27
4.4
2.4
14.96
15.30
%
0.14
14
83
20
314
0.63
1.25
1.5
1.4
—
—
—
0
0
5
19
2.64
1.21
1.0
1.1
—
—
—
0
0
13
71
1.84
1.20
1.1
1.1
0.50
0.58
u/ml
—
7
32
21
133
1.59
1.18
3.2
2.5
—
—
—
0
0
28
190
1.49
1.17
1.5
1.5
—
—
—
0
0
58
448
1.31
1.17
15.6
9.5
—
—
—
0
0
48
363
1.34
1.12
1.6
1.6
—
—
—
0
0
16
96
1.68
1.10
6.4
6.3
10.20
7.14
mmol/l
0.66
11
82
10
52
1.93
1.06
2.2
1.9
—
—
—
0
0
66
530
1.26
1.01
1.6
1.4
—
—
—
0
0
43
329
1.32
0.96
2.8
2.7
—
—
—
0
0
104
886
1.20
0.93
3.3
4.0
21.94
17.66
ug/l
0.09
89
752
214
1931
1.14
0.93
4.6
3.6
—
—
—
0
0
58
465
1.26
0.92
1.2
1.3
—
—
—
0
0
16
102
1.58
0.91
1.3
1.1
—
—
—
0
0
63
514
1.24
0.87
1.2
1.2
—
—
—
0
0
8
43
1.87
0.87
1.5
1.3
—
—
—
0
0
8
44
1.83
0.86
2.5
1.6
—
—
—
0
0
14
88
1.60
0.84
3.0
2.5
—
—
—
0
0
6
31
1.94
0.84
1.0
1.1
169.17
172.85
iu/ml
—
6
31
10
57
1.76
0.84
1.2
1.1
—
74.00
—
0
10
10
57
1.76
0.84
1.5
1.2
—
—
—
0
0
78
655
1.21
0.83
1.5
1.4
—
—
—
0
0
49
395
1.25
0.77
1.4
1.2
155.58
139.43
iu/ml
0.11
21
154
16
107
1.50
0.76
2.4
1.9
91.25
89.35
%
1.15
16
107
0
28
0.00
0.76
0.0
3.4
—
29.26
—
0
19
10
59
1.70
0.76
1.4
1.3
—
—
—
0
0
61
507
1.22
0.74
3.7
3.3
—
—
—
0
0
18
125
1.45
0.73
3.7
1.9
—
—
—
0
0
13
84
1.56
0.72
1.2
1.1
1.40
1.49
g/l
0.43
13
72
11
68
1.62
0.72
1.1
1.0
0.10
0.79
u/ml
—
6
36
51
419
1.23
0.70
2.9
2.4
—
—
—
0
0
5
28
1.79
0.66
1.2
1.9
—
—
—
0
0
11
70
1.58
0.65
3.7
1.3
—
—
—
0
0
7
44
1.60
0.65
3.6
3.2
—
—
—
0
0
24
181
1.33
0.63
3.3
2.1
122.18
125.73
g/l
0.22
17
133
16
113
1.42
0.61
3.1
2.8
—
—
—
0
0
8
50
1.61
0.61
4.6
2.3
—
—
—
0
0
22
165
1.34
0.61
1.5
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
19.69
—
0
13
8
54
1.49
0.57
1.4
1.2
—
—
—
0
0
54
459
1.19
0.55
2.0
2.0
13.33
12.64
nmol/l
0.21
47
409
6
37
1.63
0.55
5.8
3.6
97.50
119.03
nmol/l
—
6
37
37
303
1.23
0.55
1.1
1.1
—
193.50
titre
—
0
6
26
204
1.28
0.54
2.4
2.7
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
9
60
1.50
0.54
1.3
1.4
—
—
—
0
0
11
158
0.69
0.53
1.1
1.4
—
—
—
0
0
12
83
1.45
0.52
1.2
1.3
—
—
nmol/l
—
0
0
17
225
0.75
0.51
1.6
1.6
—
—
—
0
0
13
92
1.42
0.50
1.4
1.2
—
—
—
0
0
9
65
1.39
0.50
1.0
1.1
—
—
—
0
0
21
163
1.29
0.48
2.6
4.0
13.06
28.08
mg/l
3.24
15
108
12
85
1.42
0.47
1.1
1.1
0.37
1.95
u/ml
—
7
50
7
51
1.38
0.44
1.3
1.1
—
—
—
0
0
21
166
1.27
0.43
2.5
3.3
187.00
2276.90
u/ml
0.76
21
155
13
96
1.36
0.41
1.2
1.4
18639.29
29279.11
e6/l
—
7
57
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
8
59
1.36
0.41
1.1
1.2
—
—
—
0
0
24
195
1.24
0.40
1.0
1.2
—
—
—
0
0
18
141
1.28
0.40
1.8
1.7
48.78
40.52
nmol/l
0.62
18
135
5
34
1.47
0.40
1.2
1.4
—
—
—
0
0
12
160
0.75
0.40
1.1
1.4
—
—
—
0
0
15
193
0.77
0.39
12.1
6.5
10.67
11.31
mmol/l
0.32
15
175
15
193
0.77
0.39
12.1
6.5
105.47
105.49
mmol/l
0.01
15
175
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
12
159
0.75
0.38
1.1
1.4
—
—
—
0
0
12
158
0.76
0.37
1.1
1.4
—
—
—
0
0
8
114
0.70
0.37
1.1
1.5
—
—
—
0
0
20
245
0.81
0.36
1.1
1.1
—
—
—
0
0
13
99
1.32
0.35
1.5
1.8
173.69
216.39
pmol/l
0.85
13
92
6
42
1.43
0.35
3.7
1.4
—
—
—
0
0
9
125
0.72
0.35
1.9
1.5
—
—
—
0
0
6
44
1.37
0.34
2.3
1.5
—
—
—
0
0
6
44
1.37
0.34
4.7
1.5
9.83
9.74
mmol/l
—
6
44
12
93
1.29
0.30
1.3
1.5
—
—
—
0
0
19
158
1.21
0.28
2.6
1.6
2.45
5.18
iu/l
—
10
48
8
63
1.27
0.27
1.0
1.0
—
—
—
0
0
12
150
0.80
0.27
1.4
1.2
—
—
—
0
0
5
73
0.68
0.26
1.0
1.6
—
—
—
0
0
9
76
1.19
0.24
6.0
3.3
—
—
—
0
0
27
236
1.15
0.24
3.1
3.3
0.77
0.82
nmol/l
0.23
19
187
12
146
0.82
0.22
1.1
1.4
—
—
—
0
0
5
41
1.22
0.22
7.4
6.6
—
—
—
0
0
67
719
0.93
0.21
1.8
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
8.36
—
0
5
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.54
—
0
6
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
48
1.25
0.20
1.2
1.6
175.67
80.67
umol/l
—
6
48
6
49
1.23
0.20
1.0
1.3
—
—
—
0
0
25
222
1.13
0.19
1.1
1.1
—
—
—
0
0
10
81
1.24
0.19
1.1
1.1
—
—
—
0
0
10
81
1.24
0.19
1.1
1.1
—
—
—
0
0
43
465
0.92
0.17
1.1
1.4
—
—
—
0
0
150
1446
1.04
0.17
3.4
3.1
0.76
0.80
ug/l
0.32
105
966
8
70
1.14
0.16
1.0
1.1
—
—
—
0
0
11
92
1.20
0.16
1.6
2.2
—
—
—
0
0
9
80
1.13
0.15
1.1
1.1
—
—
—
0
0
8
97
0.82
0.13
1.6
5.1
337.88
362.34
umol/l
—
8
88
9
108
0.83
0.13
1.0
1.7
—
—
—
0
0
39
416
0.93
0.12
3.9
3.8
—
—
—
0
0
10
86
1.16
0.11
1.2
1.4
—
—
—
0
0
5
45
1.11
0.10
7.2
3.2
—
—
—
0
0
5
46
1.09
0.09
1.4
1.2
172.20
139.53
nmol/l
—
5
46
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
36
341
1.06
0.08
7.1
5.0
1.42
1.55
%
0.85
36
320
10
88
1.14
0.08
1.4
1.3
—
—
—
0
0
228
2252
1.02
0.06
3.5
2.9
—
—
—
0
0
35
340
1.03
0.03
6.8
5.1
0.80
0.91
%
1.16
35
320
11
118
0.93
0.02
2.7
2.6
—
—
—
0
0
21
218
0.96
0.02
5.7
4.9
—
—
—
0
0
12
124
0.97
0.00
1.0
1.2
—
—
—
0
0
10
97
1.03
0.00
1.3
1.6
—
—
—
0
0
17
169
1.01
0.00
1.0
1.1
—
—
—
0
0
33
335
0.98
0.00
3.8
3.2
701.71
4351.64
u/ml
0.64
28
287
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.4
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
14.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
183.00
—
0
5
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
1.58
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint H7_RETINAHAEMORR and mortality.

Females

Parameter HR [95% CI] p-value
H7_RETINAHAEMORR 0.987 [0.87, 1.12] 0.838
Birth year 0.998 [0.99, 1.01] 0.6

During the follow-up period (1.1.1998 — 31.12.2019), 1022 out of 3021 females with H7_RETINAHAEMORR died.

Males

Parameter HR [95% CI] p-value
H7_RETINAHAEMORR 1.254 [1.05, 1.49] 0.011
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 664 out of 2055 males with H7_RETINAHAEMORR died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETINAHAEMORR.

N-year risk Females Males
1 0.073% 0.242%
5 0.625% 1.341%
10 1.745% 3.327%
15 3.176% 6.081%
20 5.491% 10.27%

Relationships between endpoints

↥

Index endpoint: H7_RETINAHAEMORR – Retinal haemorrhage

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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