ovarian dysfunction: The inability of the ovaries to function.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleonly females |
293218 |
2. Check conditionsNone |
293218 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2888 |
4. Check minimum number of eventsNone |
2888 |
5. Include endpoints |
3453 |
6. Filter based on genotype QC (FinnGen only) |
3215 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E20-E35
- Name in latin
- Dysfunctio ovarialis
Similar endpoints
↥List of similar endpoints to
Ovarian dysfunction
based on the number of shared cases.
Similar with more cases:
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17415 | 17415 | - |
| Only index persons | 16983 | 16983 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.50 | 0.50 | - |
| Only index persons | 0.62 | 0.62 | - |
| Median age at first event (years) | |||
| Whole population | - | 28.41 | - |
| Only index persons | - | 28.30 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3215 | 3215 | - |
| Unadjusted period prevalence (%) | 1.14 | 1.14 | - |
| Median age at first event (years) | 29.74 | 29.74 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3453
- Matched controls
- 34530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G03DB01
ATC
dydrogesterone; oral
6.4
307.7
1558
3924
A10BA02
ATC
metformin; oral
5.9
307.7
1230
2954
E28.3
ICD-10 Finland
Primary ovarian failure
244.7
307.7
410
19
121
Kela drug reimbursment
Severe hypofunction of sexual glands
34.0
307.7
540
187
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
384.6
307.7
2353
191
N97.0
ICD-10 Finland
Female infertility associated with anovulation
20.9
307.7
962
627
N91.1
ICD-10 Finland
Secondary amenorrhoea
9.4
307.7
543
672
L68.0
ICD-10 Finland
Hirsutism
16.6
279.4
239
154
N97.9
ICD-10 Finland
Female infertility, unspecified
4.0
219.4
767
2326
L02BG04
ATC
letrozole; oral
4.4
213.9
620
1638
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
4.8
165.7
405
927
G03GA01
ATC
chorionic gonadotrophin; parenteral
4.1
159.0
494
1359
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.6
154.4
1998
12077
E66.01
ICD-10 Finland
Obesity due to excess calories
3.3
151.9
703
2511
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
11.7
146.6
152
135
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
4.3
140.8
399
1022
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.7
129.0
892
3939
2564A
ICD-9 Finland
Ovarian dysfunction, Polycystic ovaries
+∞
123.7
118
*
G03GB02
ATC
clomifene; oral
6.2
117.2
208
355
E22.1
ICD-10 Finland
Hyperprolactinaemia
53.5
110.3
63
12
G03FB08
ATC
dydrogesterone and estrogen; systemic
4.0
106.5
325
874
E28.8
ICD-10 Finland
Other ovarian dysfunction
222.9
105.2
108
5
E66.8
ICD-10 Finland
Other obesity
3.2
91.9
392
1311
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.1
89.8
1414
8648
C03DA01
ATC
spironolactone; oral
3.7
87.8
300
870
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.9
86.1
462
1759
G03GA02
ATC
human menopausal gonadotrophin; parenteral
3.7
85.5
288
827
G03GA06
ATC
follitropin beta; parenteral
4.0
84.9
259
694
N91.2
ICD-10 Finland
Amenorrhoea, unspecified
7.1
83.6
128
187
TLW00
NOMESCO Finland
Insemination
3.9
80.8
251
681
G03DA02
ATC
medroxyprogesterone; systemic
3.3
80.5
327
1059
G03GA05
ATC
follitropin alfa; parenteral
3.1
77.0
360
1266
G03DA04
ATC
progesterone; systemic, rectal, vaginal
4.0
75.6
226
596
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
3.4
75.3
297
943
G03FB06
ATC
medroxyprogesterone and estrogen; systemic
4.0
74.7
225
597
N91.3
ICD-10 Finland
Primary oligomenorrhoea
17.2
73.9
61
36
G03HB01
ATC
cyproterone and estrogen; oral
2.1
70.5
834
4510
25690
ICD-8 Finland
Ovarian dysfunction, Syndroma Stein-Leventhal
+∞
70.0
67
*
N91.5
ICD-10 Finland
Oligomenorrhoea, unspecified
7.3
69.5
103
145
Z31.2
ICD-10 Finland
In vitrofertilization
5.8
67.5
126
225
25610
ICD-8 Finland
Ovarian dysfunction, Hypofunction
+∞
65.8
63
*
T90
ICPC
Diabetes non-insulin dependent
2.5
64.5
441
1884
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.6
62.8
399
1645
E66.00
ICD-10 Finland
Metabolic syndrome
3.6
62.7
220
647
X05
ICPC
Menstruation absent/scanty
3.9
60.4
182
482
E28.9
ICD-10 Finland
Ovarian dysfunction, unspecified
307.7
59.5
60
*
N97.8
ICD-10 Finland
Female infertility of other origin
3.4
59.0
228
713
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.3
58.4
504
2385
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.2
58.4
542
2645
103
Kela drug reimbursment
Diabetes, insulin-treated
2.3
58.1
508
2417
H01CC01
ATC
ganirelix; parenteral
2.8
54.3
290
1092
E28.1
ICD-10 Finland
Ovarian dysfunction: Androgen excess
536.2
53.7
53
*
H02AB09
ATC
hydrocortisone; systemic
5.4
52.6
104
196
E66.9
ICD-10 Finland
Obesity, unspecified
3.0
51.5
234
805
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
2.3
50.3
441
2093
N91.0
ICD-10 Finland
Primary amenorrhoea
10.7
48.9
53
50
TLW12
NOMESCO Finland
Insertion of frozen embryo
3.3
48.6
190
598
LCA06
NOMESCO Finland
Biopsy of endometrium
2.1
48.0
549
2891
E28.0
ICD-10 Finland
Ovarian dysfunction: Estrogen excess
+∞
43.8
42
*
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
5.5
43.0
83
153
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.8
42.9
761
4625
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.2
42.8
171
545
N97.4
ICD-10 Finland
Female infertility associated with male factors
3.0
41.8
187
637
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
41.7
40
*
Z31.1
ICD-10 Finland
Artificial insemination
5.5
41.5
81
151
H03AA01
ATC
levothyroxine sodium; systemic
1.8
41.1
846
5367
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.9
40.9
123
325
T82
ICPC
Obesity
2.6
40.2
240
954
G47.3
ICD-10 Finland
Sleep apnoea
2.0
40.0
501
2712
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.2
39.6
158
503
G03DC02
ATC
norethisterone; oral
2.2
39.3
343
1618
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
39.2
728
4473
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
38.1
727
4498
JAH01
NOMESCO Finland
Laparoscopy
2.5
37.9
243
999
1413
FHL
Laparoscopy and other therapeutic procedure
4.1
37.7
104
258
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.9
37.1
511
2854
H01AC01
ATC
somatropin; parenteral
+∞
35.5
34
*
LA2HE
NOMESCO Finland
Repeated measurement of ovarian cyst
4.1
35.4
98
244
G03GA04
ATC
urofollitropin; parenteral
6.0
35.1
62
105
N02AX02
ATC
tramadol; systemic, rectal
1.6
34.8
1087
7639
G03FB05
ATC
norethisterone and estrogen; systemic
2.4
34.8
259
1141
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
34.1
1251
9126
E66
ICD-10 Finland
Obesity
2.3
33.8
272
1238
A10BJ06
ATC
semaglutide; parenteral
3.1
33.4
144
480
A10BK03
ATC
empagliflozin; oral
2.7
33.1
179
676
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
5.6
32.8
62
112
L02AE01
ATC
buserelin; implant, nasal, parenteral
4.0
32.8
94
240
XLA10, ,
NOMESCO Finland
2.5
32.8
207
845
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
32.6
579
3492
H02AA02
ATC
fludrocortisone; oral
12.4
32.4
32
26
B01AB05
ATC
enoxaparin; parenteral
1.7
31.4
789
5230
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
31.3
30
*
LBF00
NOMESCO Finland
Perfusion of Fallopian tube
6.3
31.2
52
83
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
31.1
421
2330
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
30.9
202
838
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.9
30.4
446
2531
A02BC02
ATC
pantoprazole; systemic
1.5
30.4
1946
15888
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.2
30.3
284
1376
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
30.1
694
4491
SPAT1262
SPAT
Handing over of treatment supplies
1.9
29.5
386
2110
Z31.3
ICD-10 Finland
Other assisted fertilization methods
5.3
29.4
59
113
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
10.4
28.9
32
31
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
28.4
415
2351
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.2
27.8
244
1150
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
27.6
952
6775
Z31.6
ICD-10 Finland
General counselling and advice on procreation
3.4
27.5
101
306
C07AB07
ATC
bisoprolol; oral
1.6
27.4
829
5725
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
27.3
1456
11355
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.7
27.2
641
4162
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
27.1
26
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
27.0
515
3157
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
8.2
26.5
35
43
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
6.5
26.0
42
65
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.6
25.8
835
5842
W15
ICPC
Infertility/subfertility female
3.4
25.8
95
288
N06AX16
ATC
venlafaxine; oral
1.7
25.8
602
3893
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
25.7
845
5933
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.6
25.6
631
4135
J02AC01
ATC
fluconazole; systemic
1.5
25.2
1713
13929
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
7.0
25.0
38
55
UJF32
NOMESCO Finland
Coloscopy
1.7
25.0
543
3444
1410
FHL
Laparoscopy
3.3
25.0
94
289
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
3.2
24.9
102
330
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
24.4
521
3289
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
241.6
23.7
24
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
23.6
154
638
R4190
NOMESCO Finland
Nutritional therapy
2.6
23.5
140
555
LA2JE
NOMESCO Finland
Follow-up of menstrual cycle with repeated measurement of ovarian cyst
4.4
23.4
58
133
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
23.3
427
2581
SPAT1301
SPAT
No procedures
1.5
23.2
987
7297
25691, ,
ICD-8 Finland
+∞
22.9
22
*
R51.80
ICD-10 Finland
Headache
1.6
22.9
708
4885
N03AX12
ATC
[U] gabapentin; oral
1.7
22.7
428
2608
H01CA02
ATC
nafarelin; nasal
2.2
22.4
192
897
A10AC01
ATC
insulin (human); parenteral
2.1
22.2
226
1128
SPAT1263
SPAT
Sampling
1.4
22.2
1515
12226
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
22.2
373
2199
N05AH04
ATC
quetiapine; oral
1.6
22.2
693
4791
TLW20
NOMESCO Finland
Medical ovulation induction
6.7
22.1
35
53
G03FB09
ATC
levonorgestrel and estrogen; systemic
4.4
22.0
55
127
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
21.9
616
4157
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.4
21.8
152
649
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.8
21.5
319
1810
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
20.5
339
1986
N06AB04
ATC
citalopram; systemic
1.5
20.4
654
4537
M79.7
ICD-10 Finland
Fibromyalgia
2.2
20.3
169
780
6280A
ICD-9 Finland
Infertility, female, Associated with anovulation[STERILITAS ET INFERTILITAS ANOVULATORIA PRIM]
20.9
19.9
29
14
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
+∞
19.8
19
*
25699
ICD-8 Finland
Ovarian dysfunction, Other and unspecified
+∞
19.8
19
*
A02BC05
ATC
esomeprazole; systemic
1.4
19.7
1086
8386
J01MA02
ATC
ciprofloxacin; systemic
1.5
19.6
925
6935
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
105.7
19.6
21
*
G03FA01
ATC
norethisterone and estrogen; systemic
1.9
19.6
279
1563
SPAT1310
SPAT
Counselling related to known health issue
1.4
19.5
1102
8542
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
19.4
270
1500
B02AA02
ATC
tranexamic acid; systemic
1.5
19.4
614
4243
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
19.4
682
4821
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
19.2
203
1028
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
19.2
196
980
A12AA04
ATC
calcium carbonate; oral
7.9
19.1
26
33
205
Kela drug reimbursment
Chronic hypertension
1.9
18.8
233
1246
N06AX21
ATC
duloxetine; oral
1.7
18.8
405
2551
25698
ICD-8 Finland
Ovarian dysfunction, Alia definita
+∞
18.8
18
*
M54.5
ICD-10 Finland
Low back pain
1.4
18.7
1233
9804
C08CA01
ATC
amlodipine; oral
1.6
18.5
467
3062
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.4
18.4
127
540
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
18.3
232
1250
L17
ICPC
Foot/toe symptom/complaint
1.5
18.3
821
6088
WX704
NOMESCO Finland
Intubation
1.9
18.3
242
1324
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
18.0
247
1366
A02BC01
ATC
omeprazole; systemic
1.5
18.0
752
5497
TLW10
NOMESCO Finland
Transfer of fresh embryo
2.3
17.9
137
610
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
3.7
17.8
57
158
E, ,
ICD-9 Finland
7.6
17.8
25
33
N97.1
ICD-10 Finland
Female infertility of tubal origin
3.0
17.8
76
253
R03AC02
ATC
salbutamol; inhalant
1.4
17.8
1921
16500
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
17.7
247
1373
N02BE01
ATC
paracetamol; systemic, rectal
1.5
17.6
2889
26650
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
17.6
2567
23152
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
17.5
876
6620
E28
ICD-10 Finland
Ovarian dysfunction
28.9
17.4
23
8
N91
ICD-10 Finland
Absent, scanty and rare menstruation
4.9
17.3
38
79
N02AA05
ATC
oxycodone; systemic
1.8
17.3
245
1369
N03AX16
ATC
[U] pregabalin
1.5
17.1
547
3779
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
17.1
301
1795
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
17.1
329
2011
E66.0
ICD-10 Finland
Obesity due to excess calories
4.8
17.0
38
80
R02
ICPC
Shortness of breath/dyspnoea
1.7
17.0
347
2153
A02BC03
ATC
lansoprazole; oral
1.5
17.0
627
4466
H02AB06
ATC
prednisolone; systemic
1.4
16.9
1310
10651
C03CA01
ATC
furosemide; systemic
1.8
16.8
288
1703
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.7
16.8
299
1787
R06.0
ICD-10 Finland
Dyspnoea
1.5
16.8
631
4509
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
16.7
1183
9470
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
5.2
16.7
34
66
A10BJ02
ATC
liraglutide; parenteral
2.8
16.6
84
307
J01DB01
ATC
cefalexin; oral
1.5
16.6
2814
25889
A10BH01
ATC
sitagliptin; oral
2.3
16.6
123
541
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.7
16.5
1090
13437
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
16.5
396
2561
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
16.5
1163
9301
P01AB01
ATC
metronidazole; oral, rectal
1.4
16.5
1373
11275
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
16.2
733
5428
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
15.8
1093
8701
G03DB02
ATC
megestrol; oral
2.9
15.7
74
261
8113
FHL
Fractional scraping
2.6
15.6
87
335
SPAT1153
SPAT
Removal of sutures
1.4
15.5
706
5229
X07
ICPC
Menstruation irregular/frequent
2.2
15.4
132
617
H01
ICPC
Ear pain/earache
1.5
15.4
509
3537
N06AB10
ATC
escitalopram; oral
1.4
15.3
898
6951
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
15.2
635
4622
N06AX12
ATC
bupropion; oral
1.6
15.2
354
2271
L03
ICPC
Low back symptom/complaint
1.4
15.2
955
7476
WX725
NOMESCO Finland
Noninvasive ventilation
2.1
15.1
149
736
OAB72
NOMESCO Finland
Weight control and weight loss guidance
3.3
15.0
55
167
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
14.9
605
4378
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
14.8
1462
12252
LAC21
NOMESCO Finland
Laparoscopic destruction of lesion of ovary
2.8
14.8
73
264
N06AX11
ATC
mirtazapine; oral
1.4
14.7
1014
8047
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.8
14.6
74
271
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
14.6
1862
16178
LAA97
NOMESCO Finland
Other laparoscopic puncture of ovary
80.5
14.6
16
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
14.3
645
4757
C09CA06
ATC
candesartan; oral
1.5
14.3
545
3897
G02CB03
ATC
cabergoline; oral
4.1
14.2
39
97
M79.6
ICD-10 Finland
Pain in limb
1.3
14.2
1285
10613
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
0.6
14.2
255
4084
A10BK01
ATC
dapagliflozin; oral
2.3
14.2
108
481
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
14.1
414
2801
E21.0
ICD-10 Finland
Primary hyperparathyroidism
42.7
14.1
17
*
J01FF01
ATC
clindamycin; systemic
1.4
14.1
735
5566
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
14.0
404
2722
B03BA03
ATC
hydroxocobalamin; parenteral
2.3
14.0
100
434
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
3.2
13.9
54
170
S18
ICPC
Laceration/cut
1.3
13.9
1076
8682
UKC02
NOMESCO Finland
Cystoscopy
1.8
13.8
206
1169
R53
ICD-10 Finland
Malaise and fatigue
1.4
13.8
827
6404
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
53.6
13.8
16
*
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
13.8
239
1419
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
13.7
1265
10464
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
13.7
342
2230
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
13.6
555
4015
N06AB03
ATC
fluoxetine; oral
1.5
13.6
401
2715
A10BG03
ATC
pioglitazone; oral
4.2
13.6
35
83
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
13.6
150
772
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
4.3
13.6
34
79
A10AE04
ATC
insulin glargine; parenteral
1.9
13.6
181
993
301
Kela drug reimbursment
Growth hormone
+∞
13.5
13
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
13.5
13
*
L02AE03
ATC
goserelin; implant
3.4
13.5
48
143
E34.35
ICD-10 Finland
Abnormal growth retardation
140.5
13.5
14
*
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.0
13.4
151
782
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
13.4
599
4407
SPAT1260
SPAT
Consultation of another employee
1.5
13.3
524
3764
C08CA05
ATC
nifedipine; systemic
2.1
13.3
124
600
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.7
13.3
268
1658
N03AE01
ATC
clonazepam; systemic
2.0
13.2
135
676
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
13.2
389
2634
SPAT1283
SPAT
Restricted health certificate
1.3
13.1
1033
8341
L02AE02
ATC
leuprorelin; implant, parenteral
2.3
13.1
98
434
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
13.0
531
3841
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
2.1
13.0
119
572
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
12.9
349
2319
G03FA12
ATC
medroxyprogesterone and estrogen; systemic
2.2
12.8
106
490
WX002
NOMESCO Finland
Sedation and analgesia
1.5
12.7
393
2686
D07AC01
ATC
betamethasone; topical
1.3
12.7
995
8018
G44.2
ICD-10 Finland
Tension-type headache
1.4
12.6
541
3949
G03HA01
ATC
cyproterone; systemic
12.3
12.6
22
18
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
4.8
12.6
28
59
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
1.8
12.5
179
1003
C10AA05
ATC
atorvastatin; oral
1.5
12.5
457
3233
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.2
12.5
102
468
M79.1
ICD-10 Finland
Myalgia
1.4
12.5
535
3901
E27.0
ICD-10 Finland
Other adrenocortical overactivity
+∞
12.5
12
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.7
12.5
211
1244
Q96.0
ICD-10 Finland
Karyotype 45,X
130.5
12.4
13
*
L68.9
ICD-10 Finland
Hypertrichosis, unspecified
13.2
12.4
21
16
N05BA04
ATC
oxazepam; oral
1.4
12.4
805
6302
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.0
12.4
54
183
LAE10
NOMESCO Finland
Unilateral oophorectomy
5.8
12.3
22
38
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
12.2
686
5243
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
2.8
12.2
58
206
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
12.2
152
816
W12
ICPC
Contraception intrauterine
0.7
12.1
426
5908
P76
ICPC
Depressive disorder
1.6
12.1
325
2156
LCD00
NOMESCO Finland
Hysterectomy
2.2
12.0
103
483
C07AB02
ATC
metoprolol; systemic
1.6
12.0
289
1869
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
11.9
261
1647
M02AA07
ATC
piroxicam; topical
1.4
11.9
724
5604
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
2.0
11.9
122
613
K02.1
ICD-10 Finland
Caries of dentine
1.3
11.8
2198
19820
D01
ICPC
Abdominal pain/cramps general
1.4
11.8
484
3502
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
11.7
353
2399
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
11.7
1225
10252
N03AX09
ATC
lamotrigine; oral
1.7
11.7
224
1367
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
11.7
252
1586
E23.05
ICD-10 Finland
Lack of TSH
16.4
11.7
18
11
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
11.6
164
917
ACC51
NOMESCO Finland
Release of median nerve
1.7
11.6
199
1178
J01FA06
ATC
roxithromycin; oral
1.3
11.6
1106
9140
N06AB06
ATC
sertraline; oral
1.5
11.6
454
3255
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
11.5
228
1403
N83.1
ICD-10 Finland
Corpus luteum cyst
2.3
11.5
81
350
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.0
11.4
127
656
M25.5
ICD-10 Finland
Pain in joint
1.3
11.4
1021
8358
102
Kela drug reimbursment
Diabetes insipidus
120.4
11.4
12
*
A10AB05
ATC
insulin aspart; parenteral
1.8
11.4
164
922
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.4
11.3
745
5836
6146A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female
4.2
11.3
29
69
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
11.2
183
1068
A10BD07
ATC
metformin and sitagliptin; systemic
2.8
11.2
53
188
M01AE02
ATC
naproxen; oral, rectal
1.3
11.2
1978
17658
C09AA05
ATC
ramipril; oral
1.6
11.1
236
1478
C10AA01
ATC
simvastatin; oral
1.5
11.1
344
2353
R42
ICD-10 Finland
Dizziness and giddiness
1.4
11.1
534
3973
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
8.0
11.1
24
30
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
11.0
451
3259
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
11.0
84
376
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
1.9
11.0
140
758
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
2.1
11.0
99
474
SGA01
NOMESCO Finland
Emergency treatment
1.4
10.9
602
4579
N06AB05
ATC
paroxetine; oral
1.7
10.9
195
1167
L15
ICPC
Knee symptom/complaint
1.4
10.9
616
4704
C10AA07
ATC
rosuvastatin; oral
1.4
10.9
449
3246
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
10.9
244
1550
C09CA01
ATC
losartan; oral
1.5
10.8
329
2239
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
10.8
199
1201
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
10.8
2217
20123
E89.4
ICD-10 Finland
Postprocedural ovarian failure
8.8
10.7
22
25
R96
ICPC
Asthma
1.6
10.7
265
1723
T83
ICPC
Overweight
2.2
10.7
91
426
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
10.7
99
479
EBA00
NOMESCO Finland
Extraction of tooth
1.3
10.7
1191
10021
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
60.2
10.6
12
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.6
2642
24559
P06
ICPC
Sleep disturbance
1.4
10.6
417
2989
R05
ICPC
Cough
1.3
10.6
796
6347
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.5
10.6
325
2218
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
3.9
10.6
30
77
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.5
10.6
36
105
A46
ICD-10 Finland
Erysipelas
1.7
10.5
193
1165
L04AA01
ATC
[U] ciclosporin
3.6
10.5
34
96
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
2.6
10.5
58
224
WVA20, ,
SPAT
2.3
10.4
75
327
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
10.4
239
1526
SPAT1240
SPAT
Therapeutic discussion
1.4
10.4
535
4020
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
10.4
516
3854
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
110.4
10.4
11
*
E27.2
ICD-10 Finland
Addisonian crisis
110.4
10.4
11
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
110.4
10.4
11
*
E30.1
ICD-10 Finland
Precocious puberty
+∞
10.4
10
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
10.4
10
*
Z3231
NOMESCO Finland
Registered nurse
1.4
10.4
672
5242
SFA20
NOMESCO Finland
Two-surface restoration
1.3
10.3
2044
18413
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.2
10.3
40
127
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.5
10.2
385
2736
Z3226
NOMESCO Finland
Physiotherapist
1.4
10.2
425
3077
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
10.2
1633
14337
M01AH02
ATC
rofecoxib; oral
1.7
10.2
190
1152
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.3
10.2
71
306
C09AA02
ATC
enalapril; systemic
1.7
10.1
205
1269
R03DC03
ATC
montelukast; oral
1.4
10.1
543
4109
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
3.0
10.1
43
144
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
10.1
233
1491
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
10.1
92
443
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.6
10.0
262
1727
62400
ICD-8 Finland
Malposition of uterus, Retroversion and retroflexion
14.6
10.0
16
11
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
10.0
154
885
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
10.0
500
3741
A07AA02
ATC
nystatin; oral
1.9
10.0
117
617
A03
ICPC
Fever
1.3
9.9
734
5832
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
9.9
99
493
SPAT1097
SPAT
Recording of ECG
1.6
9.9
241
1561
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
9.9
143
806
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
9.9
167
985
SPAT1254
SPAT
Administration of medicine
1.4
9.9
397
2857
WX290
NOMESCO Finland
Other blockage of nerve
1.3
9.8
1898
16998
N05BA01
ATC
diazepam; systemic, rectal
1.5
9.8
292
1978
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
2.8
9.8
46
163
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.5
9.7
33
96
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.3
9.7
73
325
L28
ICPC
Limited function/disability (L)
1.5
9.7
280
1885
6171A
ICD-9 Finland
Endometriosis of ovary
3.7
9.7
30
82
D06
ICPC
Abdominal pain localized other
1.5
9.7
338
2367
J01MA12
ATC
levofloxacin; systemic
1.5
9.7
329
2292
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
9.7
934
7694
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
9.7
1774
15783
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
9.6
631
4924
N92.5
ICD-10 Finland
Other specified irregular menstruation
1.6
9.6
245
1606
W85
ICPC
Gestational diabetes
1.5
9.6
329
2297
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
9.6
81
379
ULC02
NOMESCO Finland
Hysteroscopy
1.7
9.5
167
995
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.4
9.5
63
265
B01AC04
ATC
clopidogrel; oral
1.9
9.5
109
570
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.5
425
3116
J01FA10
ATC
azithromycin; systemic
1.3
9.5
2132
19393
A02BA02
ATC
ranitidine; systemic
1.5
9.5
333
2334
SPAT1312
SPAT
General health counselling
1.3
9.5
1164
9875
N97
ICD-10 Finland
Female infertility
2.4
9.5
62
260
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
9.4
207
1309
E30.09
ICD-10 Finland
Delayed puberty NOS
100.3
9.4
10
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.5
9.4
252
1670
B81
ICPC
Anaemia vit B12/folate deficiency
2.4
9.4
61
255
G03DC03
ATC
lynestrenol; oral
1.9
9.4
113
602
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
9.3
402
2929
QBJ30
NOMESCO Finland
Correction of abdominal apron
2.7
9.3
48
179
E03
ICD-10 Finland
Other hypothyroidism
1.6
9.2
188
1166
C08CA13
ATC
lercanidipine; oral
1.7
9.2
155
913
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
0.7
9.2
602
7597
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
9.2
147
853
Z30.4
ICD-10 Finland
Surveillance of contraceptive drugs
0.7
9.2
326
4542
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
9.2
251
1669
N03AX11
ATC
topiramate; oral
1.9
9.2
115
620
SPAT1229
SPAT
Assessment of need for aid
1.9
9.2
114
613
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
9.1
342
2427
R11
ICD-10 Finland
Nausea and vomiting
1.5
9.1
290
1993
R52.9
ICD-10 Finland
Pain, unspecified
1.5
9.1
262
1764
N71.1
ICD-10 Finland
Chronic inflammatory disease of uterus
5.0
9.1
19
38
A01
ICPC
Pain general/multiple sites
1.6
9.1
238
1570
F43.1
ICD-10 Finland
Post-traumatic stress disorder
1.7
9.1
164
987
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
4.0
9.0
25
63
K10.3
ICD-10 Finland
Alveolitis of jaws
1.6
9.0
198
1252
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
9.0
190
1190
R50.9
ICD-10 Finland
Fever, unspecified
1.4
9.0
407
2991
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
9.0
150
883
G02CB01
ATC
bromocriptine; systemic
2.2
9.0
72
330
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
8.9
333
2362
K04.0
ICD-10 Finland
Pulpitis
1.4
8.9
367
2651
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
8.9
716
5747
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.9
8.9
113
612
XF404
NOMESCO Finland
Ambulatory ECG
1.8
8.9
140
810
R73.0
ICD-10 Finland
Abnormal glucose tolerance test
2.6
8.9
50
195
127
Kela drug reimbursment
Transplant complication
3.4
8.9
31
92
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
3.3
8.9
32
97
Z31.4
ICD-10 Finland
Procreative investigation and testing
2.3
8.9
66
293
F34.1
ICD-10 Finland
Dysthymia
1.8
8.8
140
812
E66.1
ICD-10 Finland
Drug-induced obesity
4.9
8.8
19
39
RD210, ,
NOMESCO Finland
2.4
8.8
58
244
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
8.8
407
3001
D11
ICPC
Diarrhoea
1.4
8.8
486
3693
L73.2
ICD-10 Finland
Hidradenitis suppurativa
2.4
8.8
60
257
N84.0
ICD-10 Finland
Polyp of corpus uteri
1.6
8.7
197
1254
E23.2
ICD-10 Finland
Diabetes insipidus
50.1
8.7
10
*
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
2.1
8.7
83
408
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.6
8.6
49
192
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
8.6
195
1243
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
2.0
8.6
90
457
UDC00
NOMESCO Finland
Ear microscopy
1.6
8.6
186
1174
J01AA02
ATC
doxycycline; systemic
1.2
8.5
2178
19969
G03FB01
ATC
norgestrel and estrogen; systemic
3.6
8.5
27
75
N05CF02
ATC
zolpidem; oral
1.4
8.5
476
3623
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
3.4
8.5
30
90
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
8.5
1033
8733
OAB50, ,
SPAT
1.9
8.4
101
537
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
2.1
8.4
81
399
E23.03
ICD-10 Finland
Lack of ACTH
90.3
8.4
9
*
M03BX02
ATC
tizanidine; oral
1.2
8.4
1937
17551
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
8.4
497
3815
N95.0
ICD-10 Finland
Postmenopausal bleeding
1.7
8.4
145
863
F32.1
ICD-10 Finland
Moderate depressive episode
1.5
8.3
289
2021
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
2.0
8.3
92
476
2561A
ICD-9 Finland
Ovarian dysfunction, Other ovarian hyperfunction
+∞
8.3
8
*
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.4
8.3
377
2772
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
8.3
281
1957
N80.1
ICD-10 Finland
Endometriosis of ovary
1.7
8.3
153
927
N05CF01
ATC
zopiclone; oral
1.3
8.3
678
5453
EB1VA, ,
NOMESCO Finland
1.4
8.2
370
2717
Z71.8
ICD-10 Finland
Other specified counselling
1.2
8.2
1134
9719
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
8.2
242
1639
M01AH05
ATC
etoricoxib; oral
1.2
8.2
1740
15614
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
2.0
8.2
79
390
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
8.2
323
2317
S10
ICPC
Boil/carbuncle
1.7
8.1
154
939
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.8
8.1
116
653
SPAT1216
SPAT
Assessment of functional ability
1.5
8.1
243
1650
G02BA03
ATC
plastic IUD with progestogen
0.7
8.1
359
4816
N03AG01
ATC
valproic acid; systemic, rectal
1.6
8.1
164
1017
104
Kela drug reimbursment
Thyroid insufficiency
1.7
8.1
150
909
R09
ICPC
Sinus symptom/complaint
1.4
8.1
371
2732
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
8.1
269
1867
R60.0
ICD-10 Finland
Localized oedema
1.5
8.1
214
1416
WX720
NOMESCO Finland
Own respiration
1.8
8.0
110
611
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.8
8.0
116
655
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
8.0
104
568
Z2446
NOMESCO Finland
Social worker
1.6
8.0
182
1161
LCH11
NOMESCO Finland
Pharmacologic abortion
0.6
8.0
127
2106
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
1.8
8.0
112
627
G04CA02
ATC
tamsulosin; oral
2.3
8.0
57
249
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
8.0
569
4487
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
7.9
501
3883
R33
ICD-10 Finland
Retention of urine
2.1
7.9
69
328
SPAT1307
SPAT
Psychosocial counselling and guidance
1.4
7.9
363
2674
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
6.6
7.9
19
29
J01CA08
ATC
pivmecillinam; oral
1.2
7.9
1723
15482
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
7.8
217
1449
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
2.0
7.8
84
431
SGC00
NOMESCO Finland
Medication, disinfection of root canals
1.4
7.8
360
2652
H02AB04
ATC
methylprednisolone; systemic
1.4
7.8
323
2338
L08
ICPC
Shoulder symptom/complaint
1.3
7.7
489
3788
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.6
7.7
182
1172
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.6
7.7
43
168
J20
ICD-10 Finland
Acute bronchitis
1.4
7.7
287
2038
N85.1
ICD-10 Finland
Endometrial adenomatous hyperplasia
3.3
7.6
28
86
KH1AD
NOMESCO Finland
CT of urinary organs
2.1
7.6
70
339
L29.9
ICD-10 Finland
Pruritus, unspecified
1.9
7.6
85
442
XLD10
NOMESCO Finland
Gynaecological examination
2.4
7.6
52
223
A11CC02
ATC
dihydrotachysterol; oral
18.4
7.6
11
6
SFA30
NOMESCO Finland
Three-surface restoration
1.2
7.6
1110
9554
A11CC03
ATC
alfacalcidol; systemic
3.1
7.6
31
102
Q96.9
ICD-10 Finland
Turner syndrome, unspecified
25.1
7.6
10
*
B01AB10
ATC
tinzaparin; parenteral
1.5
7.5
213
1430
N96
ICD-10 Finland
Habitual aborter
2.4
7.5
48
200
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.5
7.5
228
1554
L12
ICPC
Hand/finger symptom/complaint
1.3
7.5
497
3877
N06AA09
ATC
amitriptyline; systemic
1.6
7.5
167
1062
J01EA01
ATC
trimethoprim; systemic
1.3
7.5
873
7325
H66.9
ICD-10 Finland
Otitis media, unspecified
1.4
7.5
278
1972
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.7
7.5
125
738
N83.0
ICD-10 Finland
Follicular cyst of ovary
2.1
7.4
69
336
J01DA01
ATC
[U] cefalexin
1.2
7.4
1879
17090
E26.0
ICD-10 Finland
Primary hyperaldosteronism
80.3
7.4
8
*
WW409
NOMESCO Finland
Other aferesis
13.4
7.4
12
9
SFA10
NOMESCO Finland
One-surface restoration
1.2
7.4
1921
17516
P03
ICPC
Feeling depressed
1.3
7.4
503
3939
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.3
7.3
54
240
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
+∞
7.3
7
*
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
7.3
7
*
25899
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Other and unspecified diseases of endocrine system
+∞
7.3
7
*
25600
ICD-8 Finland
Ovarian dysfunction, Hyperfunction
+∞
7.3
7
*
OAB72, ,
SPAT
2.2
7.3
56
253
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
7.3
500
3920
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.5
7.3
259
1822
JDF01
NOMESCO Finland
Laparoscopic gastroplasty
3.2
7.3
28
89
C10AB05
ATC
fenofibrate; oral
3.2
7.2
27
84
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.5
7.2
191
1263
6200A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Follicular cyst of ovary
4.3
7.2
18
42
IHZ05, ,
SPAT
1.5
7.2
211
1427
J45.1
ICD-10 Finland
Nonallergic asthma
1.6
7.2
172
1112
TLW14
NOMESCO Finland
ICSI
2.2
7.2
55
248
SPAT1050
SPAT
Extensive neurological examination
2.2
7.2
59
274
B01AB04
ATC
dalteparin; parenteral
1.7
7.2
119
701
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.5
7.2
200
1339
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
7.2
76
389
SPAT1139
SPAT
Nutrition survey
1.9
7.2
84
445
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.5
7.2
43
174
N20.1
ICD-10 Finland
Calculus of ureter
2.2
7.2
56
255
L01
ICPC
Neck symptom/complaint
1.3
7.1
527
4173
K04.1
ICD-10 Finland
Necrosis of pulp
1.4
7.1
320
2348
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
7.1
814
6811
A10AE05
ATC
insulin detemir; parenteral
1.7
7.1
112
651
K08.80
ICD-10 Finland
Toothache NOS
1.4
7.1
325
2393
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
7.1
104
592
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
7.1
275
1967
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
7.1
1350
11922
W11
ICPC
Contraception oral
0.8
7.1
541
6711
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
1.5
7.0
248
1741
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
1.7
7.0
130
789
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
10.0
7.0
13
13
O20.0
ICD-10 Finland
Threatened abortion
1.7
7.0
129
782
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
7.0
867
7315
XG410
NOMESCO Finland
Flow-volume spirometry
2.0
6.9
73
373
H70
ICPC
Otitis externa
2.1
6.9
63
305
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
6.9
35
130
A03CA02
ATC
clidinium and psycholeptics; oral
2.0
6.9
75
387
R51.81
ICD-10 Finland
Facial pain NOS
2.0
6.9
75
387
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.2
6.9
54
246
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
1.8
6.9
95
530
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
6.9
697
5744
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.9
92
509
N80.0
ICD-10 Finland
Endometriosis of uterus
1.8
6.9
95
531
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
6.8
183
1214
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.7
6.8
126
764
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
3.8
6.8
20
53
D70.82
ICD-10 Finland
Drug-induced neutropenia
2.8
6.8
33
120
HAMTE, ,
NOMESCO Finland
2.8
6.8
33
120
JAL96
NOMESCO Finland
Other excision of lesion of peritoneum
10.9
6.8
12
11
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
0.8
6.8
464
5847
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.8
767
6402
N06AX26
ATC
vortioxetine; oral
1.4
6.8
283
2051
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.5
6.8
223
1546
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
40.1
6.8
8
*
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
40.1
6.8
8
*
A10BH05
ATC
linagliptin; oral
2.5
6.8
41
167
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
1.9
6.7
81
433
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
16.7
6.7
10
6
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
16.7
6.7
10
6
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
6.7
787
6593
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
1.6
6.7
140
876
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
1.8
6.7
102
586
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
6.7
225
1564
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
7.2
6.7
15
21
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.3
6.7
24
73
62611
ICD-8 Finland
Disorders of menstruation, Oligomenorrhoea
22.6
6.7
9
*
WX402
NOMESCO Finland
General anaesthesia
1.3
6.7
574
4635
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
6.6
118
709
Z34
ICD-10 Finland
Supervision of normal pregnancy
0.7
6.6
165
2465
183
Kela drug reimbursment
Lamotrigin and topiramate
2.6
6.6
36
139
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.5
6.6
231
1620
M04AA01
ATC
allopurinol; systemic
1.9
6.6
80
429
A10BJ05
ATC
dulaglutide; parenteral
2.6
6.6
37
145
62650
ICD-8 Finland
Disorders of menstruation, Irregular
5.5
6.6
18
33
SGA03
NOMESCO Finland
Opening and preparing the root canals, complicated
1.4
6.6
322
2396
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.8
6.6
95
538
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.4
6.6
325
2422
62600
ICD-8 Finland
Disorders of menstruation, Absent
12.3
6.6
11
9
A10BX07
ATC
[U] liraglutide
3.5
6.6
22
64
-1, ,
ICPC
1.8
6.5
88
488
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.5
6.5
211
1457
G03FA14
ATC
dydrogesterone and estrogen; systemic
1.6
6.5
133
829
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
6.5
150
964
TJK01
NOMESCO Finland
Laparoscopic cholangiography
2.9
6.5
29
101
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.6
6.5
35
135
N80.9
ICD-10 Finland
Endometriosis, unspecified
1.6
6.4
129
800
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.4
6.4
251
1797
Q96.8
ICD-10 Finland
Other variants of Turner syndrome
70.0
6.4
7
*
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
70.0
6.4
7
*
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
1.4
6.4
341
2572
A01AB04
ATC
amphotericin B; local oral
2.0
6.4
66
335
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
6.4
145
927
WVA20
NOMESCO Finland
Medicine administration
2.1
6.4
58
281
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.7
6.4
122
748
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.7
6.4
119
725
G03DC05
ATC
[U] tibolone
2.3
6.4
46
203
SPAT1255
SPAT
Intravenous administration of medicine
1.6
6.3
130
811
Z2221
NOMESCO Finland
Medical doctor
1.2
6.3
837
7100
C07AA05
ATC
propranolol; systemic
1.3
6.3
702
5844
M01AX17
ATC
nimesulide; oral
1.3
6.3
356
2712
R44
ICPC
Respiratory, Preventive immunization/medic
3.3
6.3
23
71
D27.99
ICD-10 Finland
Benign tumor of the ovary (ovary), unspecified histology
3.3
6.3
23
71
JAH00
NOMESCO Finland
Laparotomy
2.3
6.3
44
192
Q96
ICD-10 Finland
Turner syndrome
+∞
6.3
6
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
6.3
6
*
2568X
ICD-9 Finland
Ovarian dysfunction, Other ovarian dysfunction
+∞
6.3
6
*
B01AA03
ATC
warfarin; systemic
1.6
6.2
134
846
R03BA01
ATC
beclometasone; inhalant
1.4
6.2
343
2601
R03AK08
ATC
formoterol and beclometasone; inhalant
1.7
6.2
114
691
S29
ICPC
Skin symptom/complaint other
1.3
6.2
481
3828
F41.09
ICD-10 Finland
UNS Panic Syndrome
1.6
6.2
136
862
UJF30
NOMESCO Finland
Ileoscopy through colon
1.4
6.2
226
1597
R00.2
ICD-10 Finland
Palpitations
1.4
6.2
254
1834
M01AG02
ATC
tolfenamic acid; oral, rectal
1.3
6.2
518
4166
K04.08
ICD-10 Finland
Other specified pulpit
1.4
6.2
292
2161
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
2.1
6.2
58
285
G93.2
ICD-10 Finland
Benign intracranial hypertension
3.4
6.1
21
62
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
1.8
6.1
79
433
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.3
6.1
567
4618
C03AA03
ATC
hydrochlorothiazide; oral
1.8
6.1
86
484
J01FA09
ATC
clarithromycin; systemic
1.2
6.1
921
7917
8307
FHL
Hysterectomy and unilateral removal of adhesions
7.7
6.1
13
17
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.2
6.1
46
207
N02AC04
ATC
dextropropoxyphene; oral
2.5
6.1
36
145
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
1.8
6.1
92
529
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.8
6.1
18
48
SPAT1325
SPAT
Vaccination
1.2
6.1
805
6828
R51
ICD-10 Finland
Headache
1.4
6.0
226
1606
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.5
6.0
159
1053
R13
ICD-10 Finland
Dysphagia
1.6
6.0
125
783
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.8
6.0
77
421
X17
ICPC
Pelvis symptom/complaint female
1.9
6.0
68
357
N04BC06
ATC
cabergoline; oral
5.2
6.0
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
228
102
23.86
314.97
1.3
1.0
7.69
5.11
nmol/l
9.80
219
96
406
328
13.89
307.65
1.3
1.1
6.87
6.07
umol/l
2.55
385
305
869
1386
8.04
307.65
1.4
1.2
13.23
9.08
u/l
8.15
735
1156
621
584
12.75
307.65
1.5
1.3
1.62
1.45
nmol/l
0.78
567
504
853
2577
4.07
247.79
1.7
1.3
287.55
299.57
mu/l
0.48
795
2270
607
1550
4.54
219.13
1.3
1.3
7.79
3.29
ug/l
11.41
528
1484
177
111
16.75
209.31
1.4
1.1
24.03
14.93
pmol/l
7.35
165
99
462
1070
4.83
187.12
1.8
1.4
0.45
0.55
nmol/l
0.66
394
905
859
3096
3.36
186.18
1.5
1.3
17.85
21.59
iu/l
2.66
740
2677
370
932
4.33
133.28
1.6
1.3
13.98
19.27
u/l
3.47
339
786
568
2503
2.52
78.75
2.4
1.7
365.19
392.57
nmol/l
2.10
532
2291
52
20
26.38
75.25
1.0
1.1
—
—
—
0
0
2952
24880
2.29
64.03
5.5
4.2
14.32
14.21
pmol/l
1.94
2811
23255
2696
22035
2.02
62.23
5.1
3.7
37.81
36.63
mmol/mol
9.77
2582
20846
224
674
3.48
61.63
1.4
1.4
29.28
32.29
nmol/l
0.69
208
612
1880
13944
1.76
56.64
4.3
3.6
6.29
6.10
mmol/l
3.91
1667
12196
3169
27922
2.64
55.79
6.4
4.8
2.49
1.84
mu/l
0.36
3066
26590
722
4063
1.98
52.86
3.3
3.4
569.35
414.28
mg/l
0.31
482
2630
1608
11617
1.72
51.33
5.0
4.6
9.05
9.30
umol/l
0.69
1509
10859
735
4213
1.95
50.76
3.9
3.9
9.04
12.36
mg/mmol
0.95
471
2761
1286
8760
1.75
50.55
4.5
3.8
36.56
37.00
g/l
2.28
1205
8160
2934
25434
2.02
47.27
4.1
3.1
5.65
5.48
mmol/l
12.24
2787
23869
2308
18615
1.72
47.22
6.9
5.9
72.52
69.86
u/l
3.55
2187
17527
1102
7358
1.73
45.41
2.5
2.3
60.88
55.88
u/l
0.36
1030
6803
1356
9710
1.65
42.16
6.0
4.5
1.22
1.21
mmol/l
0.53
1154
8259
888
5677
1.76
42.12
3.2
3.2
8.19
7.73
mmol/l
1.63
765
5062
3050
27074
2.08
42.00
11.9
8.1
3.89
3.88
mmol/l
1.53
2961
26130
3043
27027
2.06
41.24
11.8
8.1
139.40
139.44
mmol/l
0.40
2962
26167
395
1960
2.15
39.94
4.4
4.3
1.08
1.05
mmol/l
1.51
380
1825
1126
7775
1.67
39.80
6.6
6.1
1.04
1.06
inr
1.04
336
2687
1207
8623
1.61
36.51
5.3
3.9
1.22
1.22
mmol/l
0.66
1117
7915
1195
8530
1.61
36.20
2.0
1.7
94.81
99.40
pmol/l
2.97
658
4702
1509
11388
1.58
36.04
2.6
2.1
70.75
72.71
nmol/l
2.26
1420
10676
85
195
4.44
34.15
1.4
1.3
386.38
397.10
mu/l
0.07
85
182
86
203
4.32
33.32
1.4
1.2
70.64
72.35
%
0.41
86
190
1236
9042
1.57
32.97
3.1
2.7
28.09
27.32
u/l
0.32
1179
8644
66
129
5.20
32.09
1.9
1.3
1.09
2.72
nmol/l
0.80
56
93
586
3566
1.77
31.93
1.3
1.2
134.72
152.17
iu/ml
0.43
212
1397
711
4569
1.70
31.88
1.6
1.4
19.65
21.02
nmol/l
2.10
645
4087
1011
7208
1.57
29.45
2.8
2.7
2.34
2.34
mmol/l
0.31
911
6543
475
2780
1.82
29.32
3.2
2.9
0.82
0.83
mmol/l
1.21
450
2617
290
1465
2.07
27.65
1.4
1.4
—
—
—
0
0
701
4652
1.64
27.27
2.7
2.2
6265.56
6935.16
u/l
0.26
313
1912
939
6732
1.54
26.09
2.3
2.0
2.63
2.62
mg/l
0.06
832
5781
769
5273
1.59
25.98
2.3
2.0
1441.95
2904.87
umol/l
1.25
702
4784
2375
20535
1.50
25.73
4.6
3.8
448.00
1709.31
e6/l
2.17
33
211
2925
26511
1.68
25.62
4.0
3.2
2.87
2.85
mmol/l
0.75
2794
25221
813
5703
1.56
24.71
1.7
1.5
1.53
1.27
mmol/l
9.61
724
5014
918
6649
1.52
23.97
2.4
2.3
17.10
23.94
ng/l
0.93
346
2381
125
468
2.73
23.54
1.1
1.1
9.72
3194.27
iu/ml
0.95
30
149
2881
26188
1.60
22.89
3.8
3.0
1.44
1.55
mmol/l
38.74
2777
25012
2894
26341
1.61
22.79
3.9
3.1
4.73
4.76
mmol/l
1.00
2791
25205
496
3149
1.67
22.58
1.9
1.6
1209.95
1175.44
nmol/l
0.40
413
2428
2776
25042
1.55
22.56
3.5
2.8
1.35
1.13
mmol/l
40.57
2667
23863
1737
14368
1.42
22.11
5.8
5.6
0.18
0.18
e9/l
0.21
1590
12966
399
2403
1.75
22.02
3.4
3.4
4.62
4.59
pmol/l
0.24
358
2168
479
3044
1.67
21.67
2.1
2.0
2.59
2.52
g/l
2.00
443
2812
2319
20267
1.44
21.27
4.2
3.5
10.30
8.94
mm/h
8.17
2183
18990
1673
13815
1.41
21.13
5.6
5.5
0.04
0.04
e9/l
0.38
1492
12279
1668
13787
1.41
20.83
5.6
5.5
0.53
0.52
e9/l
2.26
1493
12284
1147
8879
1.44
20.75
1.4
1.3
1.46
1.62
u/ml
0.15
316
2598
414
2565
1.70
20.56
2.7
2.3
4.97
5.18
umol/l
0.21
346
2097
1580
12975
1.40
20.30
5.7
5.4
2.58
2.72
%
2.13
1492
12181
488
3172
1.63
20.10
3.0
2.6
143.06
280.11
ng/l
0.94
233
1439
1864
15774
1.39
19.88
7.9
7.7
4.14
3.95
e9/l
3.35
1658
13989
48
109
4.45
19.62
1.8
1.5
126.73
126.14
nmol/l
0.03
48
109
1727
14464
1.39
19.40
5.6
5.4
2.10
2.00
e9/l
5.16
1582
13205
1582
13066
1.39
19.29
6.1
5.6
7.49
7.70
%
2.28
1494
12303
2048
17660
1.39
19.20
3.3
2.9
60.26
56.63
ug/l
0.90
1958
16778
424
2695
1.65
19.04
2.2
2.1
21.90
23.89
%
2.20
347
2329
641
4496
1.52
18.86
1.7
1.5
8141990.99
38373701.39
pmol/l
1.82
565
3922
47
110
4.32
18.51
1.8
1.2
86.87
72.64
nmol/24h
0.69
47
110
514
3446
1.58
18.51
2.1
2.0
13.83
14.76
umol/l
2.13
483
3217
462
3026
1.61
18.35
2.3
2.5
499.92
553.50
ng/l
0.20
367
2387
1753
14808
1.37
18.21
2.7
2.4
—
—
—
0
0
3185
30030
1.78
18.20
9.6
7.6
26.75
22.92
u/l
18.12
3115
29119
1499
12417
1.37
17.27
5.9
5.5
0.63
0.66
%
1.40
1400
11582
1621
13601
1.36
17.18
5.6
5.2
56.37
56.33
%
0.05
1529
12856
178
898
2.04
16.99
3.4
2.7
5.08
5.08
kpa
0.00
165
861
1779
15167
1.36
16.89
3.5
3.1
0.00
0.00
estimate
1.79
355
3143
1635
13762
1.36
16.85
5.8
5.3
30.32
30.12
%
0.35
1545
13012
846
6405
1.42
16.58
2.0
1.7
0.74
0.86
mg/l
1.34
621
4628
170
861
2.02
16.06
3.5
2.6
1.02
1.21
mmol/l
0.39
117
597
1762
15080
1.34
15.90
4.6
4.3
0.00
0.00
estimate
0.35
363
3196
1757
15045
1.34
15.73
3.4
3.1
0.00
0.00
estimate
1.15
362
3238
332
2078
1.66
15.73
2.5
2.4
25.78
36.02
u/ml
1.69
321
2014
199
1076
1.90
15.56
3.3
2.7
90.75
65.05
ng/l
0.85
179
965
3116
29397
1.61
15.34
12.6
9.1
17.84
18.37
mg/l
0.46
2595
22395
2772
25564
1.43
14.96
9.9
7.3
97.62
96.67
ml/min/173m2
1.55
2235
20385
267
1614
1.71
14.40
2.2
2.1
0.24
0.23
g/l
1.18
251
1518
64
220
2.95
14.23
1.3
1.4
—
—
titre
—
0
0
751
5739
1.39
13.56
1.4
1.3
28.08
21.15
iu/ml
0.80
220
1805
117
549
2.17
13.56
3.8
2.8
24.52
24.50
mmol/l
0.04
108
517
430
2975
1.51
13.18
1.9
1.7
—
—
—
0
0
366
2446
1.56
13.16
3.6
2.9
30.88
33.40
%
4.55
307
1865
721
5532
1.38
12.60
2.2
1.9
198.98
128.52
u/l
0.38
697
5248
204
1194
1.75
12.36
1.1
1.1
2.16
4.40
u/ml
1.30
25
205
918
7351
1.34
12.12
1.5
1.4
1.97
2.04
g/l
0.91
554
4720
1119
9219
1.32
12.11
3.4
3.0
51.40
67.79
e6/l
0.88
713
5724
2261
20483
1.30
11.66
3.1
2.6
34.87
29.41
u/l
5.93
2176
19630
81
354
2.32
11.19
2.7
4.2
293.59
76.93
u/ml
0.63
24
111
289
1902
1.57
11.09
3.6
3.7
223.50
229.53
u/l
0.30
270
1801
20
35
5.74
11.00
1.2
1.2
—
—
—
0
0
280
1835
1.57
10.95
1.7
1.5
—
—
—
0
0
697
5434
1.35
10.83
1.3
1.3
11.72
8.93
u/ml
0.54
270
2332
807
6432
1.33
10.81
3.4
3.3
1.02
1.02
kg/l
0.38
136
974
155
873
1.81
10.72
2.6
2.5
77.68
96.30
ng/l
0.70
139
769
221
1375
1.65
10.71
1.7
1.5
—
—
—
0
0
864
6991
1.31
10.34
3.0
2.6
23.71
85.48
e6/l
2.27
649
5115
205
1270
1.65
10.11
6.2
6.7
96.29
96.59
%
0.27
196
1223
219
1384
1.62
9.98
1.4
1.3
1.69
1.11
u/ml
0.16
14
109
625
4848
1.35
9.96
2.5
2.2
10.66
9.54
e6/l
0.69
554
4254
280
1879
1.53
9.85
1.8
1.5
—
—
—
0
0
194
1203
1.65
9.54
6.6
6.9
125.57
121.20
g/l
2.79
188
1172
451
3342
1.40
9.50
2.4
2.2
2.41
2.40
mmol/l
1.20
381
2891
229
1491
1.57
9.23
6.1
6.2
13.04
13.96
kpa
1.87
218
1427
229
1492
1.57
9.20
6.0
6.3
0.58
0.70
mmol/l
0.17
177
1107
390
2837
1.42
9.12
2.5
2.0
28.59
29.10
s
1.39
383
2724
228
1491
1.57
9.02
6.2
6.2
4.94
5.00
kpa
0.49
219
1429
328
2317
1.46
8.98
4.5
4.1
—
—
—
0
0
783
6364
1.30
8.87
2.9
2.5
0.23
0.27
e6/l
0.23
580
4630
2827
26719
1.32
8.79
14.5
11.0
14.38
14.71
%
0.48
2792
26277
83
408
2.06
8.66
1.3
1.2
—
—
—
0
0
78
376
2.10
8.57
2.2
2.8
1.04
0.84
nmol/l
1.12
61
324
53
222
2.41
8.15
1.2
1.1
14.20
25.09
u/ml
—
5
22
1352
11826
1.24
8.06
3.5
3.1
—
—
—
0
0
195
1265
1.57
8.01
3.2
3.2
1.67
1.62
mmol/l
0.07
159
1041
43
165
2.63
7.94
3.0
1.4
287.56
284.74
mosm/kgh2o
0.37
34
135
136
809
1.71
7.88
6.6
6.3
24.14
24.16
mmol/l
0.03
128
765
417
3152
1.37
7.75
1.9
1.8
—
—
—
0
0
816
6777
1.27
7.64
2.2
1.8
—
—
—
0
0
701
5723
1.28
7.54
3.9
3.0
98.87
98.59
%
0.12
680
5533
276
1953
1.45
7.50
2.8
2.4
10.26
10.51
g/l
0.58
251
1806
96
526
1.85
7.37
1.3
1.4
—
—
—
0
0
172
1106
1.58
7.36
2.8
2.4
77.39
71.18
e9/l
1.29
132
796
240
1660
1.48
7.34
3.7
2.5
1.86
1.64
%
2.89
216
1471
949
8061
1.24
7.25
3.8
3.3
0.00
0.00
estimate
2.12
358
3148
46
191
2.43
7.25
1.0
1.1
92.10
86.04
%
0.83
40
151
80
418
1.94
7.11
3.6
4.8
182.86
660.66
iu/ml
—
7
41
63
304
2.09
6.97
3.3
2.6
—
—
—
0
0
175
1151
1.55
6.81
6.3
5.8
6.66
6.29
mmol/l
0.46
169
1110
302
2221
1.39
6.63
2.5
2.2
36.98
35.03
u/l
0.11
251
1876
219
1525
1.47
6.50
3.7
2.3
1.22
1.23
mmol/l
0.37
199
1288
211
1461
1.47
6.45
2.0
1.8
1.37
1.39
g/l
0.06
196
1359
17
30
5.69
6.44
1.2
1.1
15.06
11.56
pmol/l
0.66
17
30
3390
33334
1.93
6.42
19.1
13.8
4.52
4.45
e12/l
18.66
3334
32676
3390
33335
1.93
6.41
19.1
13.9
7.09
6.83
e9/l
9.13
3333
32642
3391
33351
1.93
6.36
19.1
13.9
133.30
132.49
g/l
4.30
3371
33038
92
524
1.78
6.28
1.1
1.1
120.74
116.75
%
0.75
87
470
599
4906
1.27
6.18
2.3
2.4
106.84
93.49
ug/g
0.51
454
3793
3382
33247
1.84
6.17
19.0
13.8
39.92
39.57
%
4.34
3217
31817
162
1074
1.53
6.11
2.1
2.0
—
—
—
0
0
49
228
2.17
6.00
1.5
1.3
478.14
415.66
pmol/l
0.32
43
205
90
517
1.76
5.98
5.5
4.1
1.78
1.80
%
0.04
85
482
86
489
1.78
5.92
1.4
1.3
—
—
—
0
0
190
1313
1.47
5.89
5.0
5.3
1.27
1.22
mmol/l
0.42
185
1279
3384
33298
1.81
5.77
19.1
13.9
275.71
268.91
e9/l
8.66
3333
32671
145
957
1.54
5.61
1.4
1.3
39.10
35.23
u/ml
0.07
16
74
1387
12477
1.19
5.53
8.3
7.3
0.00
0.00
e9/l
0.48
1143
10323
55
277
2.00
5.51
1.1
1.1
1.04
1.04
ratio
0.00
17
105
141
932
1.53
5.43
2.5
2.4
3.83
3.58
g/l
1.11
136
867
57
294
1.95
5.35
7.0
5.6
106.08
105.97
mmol/l
0.06
52
264
151
1022
1.50
5.22
1.7
2.1
43.47
38.93
u/l
1.75
143
967
132
870
1.54
5.17
1.4
1.3
1.89
12.12
u/ml
3.34
18
156
52
265
1.98
5.07
1.2
1.2
—
—
—
0
0
52
266
1.97
5.02
1.2
1.2
—
—
—
0
0
129
855
1.53
4.94
1.4
1.3
3.25
5.69
u/ml
0.51
14
94
1183
10575
1.18
4.94
1.9
1.8
—
—
—
0
0
57
305
1.88
4.83
2.6
2.7
32.60
121.85
ug/min
1.95
39
211
51
263
1.95
4.82
1.2
1.1
—
0.44
nmol/l
—
0
5
58
313
1.87
4.80
1.3
1.4
—
—
—
0
0
58
318
1.84
4.58
1.3
1.4
—
—
—
0
0
57
311
1.85
4.57
1.3
1.4
—
—
—
0
0
32
141
2.28
4.54
1.1
1.2
—
—
—
0
0
831
7253
1.19
4.51
2.0
1.9
—
—
—
0
0
145
1015
1.45
4.29
1.8
2.2
5.22
4.17
iu/l
0.43
53
434
66
386
1.72
4.23
1.4
1.2
—
—
—
0
0
66
386
1.72
4.23
1.4
1.2
—
—
—
0
0
55
307
1.80
4.14
1.3
1.4
—
—
—
0
0
55
307
1.80
4.14
1.3
1.4
—
—
—
0
0
177
1295
1.39
4.10
1.6
1.5
—
—
—
0
0
98
639
1.55
4.10
1.7
2.1
9.86
10.23
mg/l
0.19
91
614
55
308
1.80
4.10
1.3
1.4
—
—
—
0
0
146
1035
1.43
4.06
2.1
2.1
67.62
67.66
g/l
0.02
138
974
177
1299
1.38
4.03
2.9
3.5
7.95
40.95
ug/l
0.60
123
920
74
454
1.64
3.99
2.7
2.1
217.94
270.73
ug/l
0.18
56
394
195
1456
1.36
3.99
2.2
2.3
4.47
4.98
umol/l
0.63
138
1075
39
199
1.97
3.86
2.4
2.2
—
—
—
0
0
109
739
1.49
3.83
1.1
1.2
246.15
251.16
u/ml
0.07
67
490
42
221
1.91
3.82
1.7
1.5
—
—
—
0
0
42
221
1.91
3.82
1.7
1.5
—
—
—
0
0
129
906
1.44
3.79
2.7
2.4
168.77
160.20
%
0.61
121
850
41
217
1.90
3.67
2.3
2.2
10.93
13.23
%
1.07
41
212
113
784
1.46
3.56
1.2
1.2
—
—
—
0
0
41
220
1.87
3.54
6.1
5.4
9.76
6.42
mmol/l
0.50
35
174
36
185
1.96
3.52
1.7
1.6
—
—
—
0
0
115
804
1.45
3.49
6.7
7.8
0.67
0.71
%
0.56
115
799
126
896
1.42
3.49
1.7
1.4
—
—
—
0
0
54
317
1.71
3.48
1.8
1.6
—
—
—
0
0
54
317
1.71
3.48
1.8
1.6
—
—
—
0
0
486
4141
1.20
3.40
1.6
1.6
1.40
1.31
%
4.00
441
3750
85
563
1.52
3.38
1.5
1.3
328.55
325.99
ug/g
0.03
45
259
99
677
1.48
3.38
1.3
1.3
103.25
107.85
u/ml
0.20
15
147
69
436
1.59
3.37
2.4
1.8
0.92
2.03
ug/l
0.83
62
391
1147
10477
1.14
3.29
1.6
1.5
—
—
—
0
0
65
408
1.60
3.27
2.0
2.2
—
—
—
0
0
113
800
1.43
3.23
6.8
7.8
1.44
1.38
%
0.23
113
793
20
85
2.36
3.15
1.2
1.3
—
—
—
0
0
109
771
1.43
3.14
1.2
1.3
392.86
445.36
mg/l
0.91
103
729
1160
10633
1.14
3.13
2.3
2.3
—
—
—
0
0
1051
9575
1.14
3.11
2.2
2.2
—
—
—
0
0
43
245
1.76
3.10
3.3
3.2
22.44
24.15
mg/l
0.23
37
205
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
298
1.69
3.09
4.3
4.0
0.38
0.37
u/ml
0.04
35
155
300
2463
1.24
3.05
1.4
1.3
119.73
182.08
u/ml
1.73
276
2296
20
87
2.31
3.00
1.2
1.3
—
—
—
0
0
429
3658
1.20
2.98
2.4
2.2
0.88
1.23
e6/l
1.24
221
1951
95
664
1.44
2.94
1.2
1.4
220.66
6452.97
e6/l
0.59
82
539
95
664
1.44
2.94
1.2
1.4
2.20
20.01
e6/l
4.32
74
509
208
1645
1.28
2.92
2.6
2.1
77.22
82.77
ml/min/173m2
1.05
79
588
23
108
2.14
2.90
1.1
1.4
148.13
140.57
mmol/24h
0.21
23
108
292
2405
1.23
2.89
1.1
1.1
—
—
—
0
0
39
221
1.77
2.89
1.6
1.5
—
—
—
0
0
14
52
2.70
2.88
2.3
4.6
—
—
—
0
0
64
414
1.56
2.88
1.8
1.6
—
—
—
0
0
17
70
2.44
2.87
2.4
3.4
63.04
120.24
ng/l
0.44
12
40
15
58
2.59
2.87
2.5
2.5
—
—
—
0
0
104
750
1.40
2.73
1.1
1.1
—
—
—
0
0
106
768
1.39
2.71
1.4
1.3
19.71
40.03
u/ml
1.24
12
73
63
413
1.54
2.69
2.6
1.9
131.65
130.69
g/l
0.17
54
311
125
932
1.35
2.69
2.1
2.0
—
—
—
0
0
244
1992
1.24
2.64
2.7
2.3
—
—
—
0
0
54
344
1.58
2.62
1.1
1.1
—
—
—
0
0
41
245
1.68
2.56
3.3
3.2
33.07
49.93
mg/l
0.43
34
206
6
11
5.46
2.54
1.0
1.1
—
—
—
0
0
43
261
1.66
2.54
1.2
1.2
—
—
—
0
0
399
3434
1.18
2.52
2.7
2.3
5.37
5.19
e6/l
0.10
191
1732
37
216
1.72
2.52
2.5
2.6
0.23
0.20
e9/l
0.45
32
182
63
420
1.51
2.51
1.8
1.5
—
—
—
0
0
55
356
1.55
2.51
1.0
1.1
190.62
196.17
mg/l
0.19
50
312
92
661
1.40
2.50
1.1
1.1
3.14
2.82
u/ml
0.12
42
385
52
333
1.57
2.48
2.2
1.8
16.41
16.85
%
0.34
25
149
82
579
1.43
2.46
1.2
1.2
3.03
3.86
u/ml
0.52
31
244
17
76
2.24
2.44
1.8
2.3
—
—
—
0
0
175
1390
1.27
2.42
1.6
1.7
—
—
—
0
0
27
145
1.87
2.41
1.7
1.6
—
—
—
0
0
27
145
1.87
2.41
1.7
1.6
—
—
—
0
0
27
145
1.87
2.41
1.7
1.6
—
—
—
0
0
16
70
2.29
2.41
1.2
1.3
—
—
—
0
0
16
70
2.29
2.41
1.2
1.3
—
—
—
0
0
6
12
5.01
2.40
1.0
1.2
—
—
—
0
0
211
1716
1.24
2.39
1.6
1.6
4.77
4.13
mg/l
0.52
170
1188
132
1013
1.32
2.37
2.9
2.2
0.16
0.22
e6/l
0.55
125
961
5
8
6.26
2.37
1.0
1.3
—
—
—
0
0
5
8
6.26
2.37
1.0
1.0
—
—
—
0
0
56
370
1.52
2.35
1.1
1.2
33.41
34.28
mg/l
0.10
48
306
96
704
1.37
2.33
2.3
2.1
1.41
1.26
g/l
0.79
87
614
32
184
1.75
2.31
1.1
1.1
—
—
—
0
0
40
245
1.64
2.31
1.5
1.6
—
—
—
0
0
134
1040
1.30
2.24
2.2
2.0
1.23
1.15
g/l
1.91
127
986
131
1014
1.30
2.23
2.2
2.1
0.24
0.22
g/l
2.38
124
962
16
73
2.20
2.21
1.9
1.2
—
—
—
0
0
524
4658
1.15
2.19
1.4
1.5
—
—
—
0
0
8
24
3.34
2.18
1.1
1.2
1.27
1.38
umol/24h
—
8
24
36
219
1.65
2.15
2.5
2.6
657.81
514.13
e6/l
1.63
31
182
43
274
1.58
2.14
1.8
1.6
—
—
—
0
0
629
5670
1.13
2.13
1.8
1.8
—
—
—
0
0
10
36
2.78
2.13
1.1
1.4
—
—
—
0
0
27
152
1.78
2.11
2.0
1.5
4.96
5.16
u/l
0.09
20
127
32
193
1.66
1.99
1.6
1.3
—
—
—
0
0
62
435
1.43
1.98
1.2
1.2
—
—
—
0
0
33
201
1.65
1.98
1.1
1.1
—
—
—
0
0
22
119
1.85
1.97
1.0
1.2
—
—
—
0
0
58
403
1.45
1.96
3.4
4.1
3.73
3.74
mmol/l
0.07
58
398
109
841
1.31
1.94
2.0
1.9
—
—
—
0
0
5
11
4.55
1.94
1.0
1.1
4.20
31.64
u/l
—
5
11
60
421
1.43
1.93
2.5
3.3
550.08
428.29
u/ml
0.08
54
353
47
314
1.50
1.93
1.2
1.2
—
—
—
0
0
40
258
1.56
1.92
1.5
1.4
—
—
—
0
0
77
569
1.36
1.85
1.1
1.1
—
—
—
0
0
5
12
4.17
1.82
1.4
2.6
—
—
—
0
0
52
360
1.45
1.81
1.2
1.2
—
—
—
0
0
57
403
1.42
1.78
1.2
1.1
—
—
—
0
0
6
18
3.34
1.74
1.7
2.1
—
—
—
0
0
73
542
1.35
1.72
3.0
3.4
3.95
3.90
e9/l
0.12
73
542
7
24
2.92
1.72
2.1
1.4
—
—
—
0
0
71
525
1.36
1.72
3.6
3.2
15.37
23.07
mg/l
0.95
39
317
118
941
1.26
1.67
2.0
2.0
6.80
4.33
ug/l
0.52
107
814
95
738
1.30
1.65
1.8
1.6
7.24
6.64
mmol/l
1.11
89
682
73
549
1.34
1.60
3.1
3.6
55.79
56.51
%
0.23
73
549
252
2180
1.17
1.57
2.4
2.3
11.70
22.73
au/ml
3.98
20
226
38
256
1.49
1.55
1.0
1.1
1.07
1.00
u/l
0.32
18
102
5
15
3.34
1.52
1.2
1.5
615.48
429.83
nmol/l
—
5
15
25
154
1.63
1.49
3.9
2.2
—
—
—
0
0
23
139
1.66
1.48
1.2
1.2
109.74
109.04
%
0.05
23
119
19
314
0.60
1.41
1.0
1.1
—
—
—
0
0
233
2025
1.16
1.40
1.3
1.3
49.98
34.34
au/ml
0.42
13
87
16
275
0.58
1.38
1.1
1.2
—
—
—
0
0
36
247
1.46
1.37
1.1
1.1
1454.94
1496.79
miu/ml
0.08
36
247
15
82
1.83
1.35
1.2
1.2
—
—
—
0
0
90
721
1.25
1.29
2.2
2.1
13.24
13.07
%
0.84
90
715
43
310
1.39
1.28
1.8
1.4
—
—
—
0
0
77
606
1.28
1.28
1.2
1.2
3.76
3.58
u/ml
0.03
21
218
37
260
1.43
1.27
1.3
1.2
—
65.15
—
0
8
121
1006
1.21
1.24
1.5
1.6
19.60
0.40
iu/ml
0.47
18
176
29
196
1.48
1.21
1.1
1.1
—
—
—
0
0
28
188
1.49
1.21
1.1
1.1
4.91
15.51
u/ml
3.69
15
122
26
172
1.52
1.20
1.2
1.1
104.91
94.09
%
0.85
11
65
6
26
2.31
1.18
1.5
1.9
—
—
—
0
0
32
222
1.45
1.18
1.5
1.4
—
—
—
0
0
344
3110
1.12
1.17
2.0
1.8
—
—
—
0
0
36
256
1.41
1.17
1.1
1.2
1.67
1.57
u/ml
0.03
20
114
13
72
1.81
1.15
1.1
1.1
—
—
—
0
0
7
30
2.34
1.12
3.0
1.7
—
—
—
0
0
25
167
1.50
1.12
1.3
1.3
110.00
205.38
titre
—
5
39
52
397
1.31
1.11
1.4
1.5
—
—
—
0
0
57
443
1.29
1.08
1.4
1.6
—
—
—
0
0
14
82
1.71
1.05
1.1
1.0
—
—
—
0
0
294
2656
1.12
1.04
1.4
1.5
—
—
—
0
0
15
90
1.67
1.04
2.5
1.6
—
—
—
0
0
107
900
1.19
1.01
1.1
1.1
—
—
—
0
0
63
501
1.26
1.01
1.5
1.5
—
—
—
0
0
162
1412
1.15
1.00
1.7
1.5
—
—
—
0
0
26
181
1.44
0.98
1.2
1.1
99.09
93.99
%
0.50
11
68
7
36
1.95
0.97
4.0
3.7
—
—
—
0
0
10
54
1.85
0.96
1.1
1.1
—
—
—
0
0
235
2108
1.12
0.96
1.6
1.5
—
—
—
0
0
13
77
1.69
0.95
1.0
1.1
—
—
—
0
0
25
174
1.44
0.95
1.5
1.4
—
—
—
0
0
14
85
1.65
0.94
3.2
3.5
—
—
—
0
0
61
491
1.25
0.91
1.3
1.4
—
4304.00
—
0
5
32
236
1.36
0.89
2.1
1.7
17.67
25.43
mg/l
—
6
63
48
376
1.28
0.89
1.5
1.8
3482.69
9182.45
e6/l
2.31
32
281
53
662
0.80
0.88
1.1
1.1
0.08
0.22
u/ml
1.02
16
164
129
1119
1.16
0.88
1.4
1.3
—
—
—
0
0
25
177
1.42
0.88
2.3
2.1
3.32
34.15
nmol/l
0.49
25
170
30
220
1.37
0.87
1.0
1.1
—
—
—
0
0
18
120
1.50
0.85
1.1
1.4
—
—
u/ml
—
0
0
34
256
1.33
0.84
1.1
1.1
18.99
7.56
iu/ml
—
10
64
8
45
1.78
0.84
1.3
1.2
—
—
—
0
0
104
892
1.17
0.83
1.1
1.1
—
—
—
0
0
17
113
1.51
0.82
1.9
2.3
13.78
15.22
umol/l
0.27
17
113
8
47
1.70
0.80
2.3
1.4
—
—
—
0
0
15
98
1.53
0.78
1.1
1.1
—
—
—
0
0
21
148
1.42
0.77
2.0
2.6
1725.71
758.55
u/ml
0.77
21
148
22
157
1.40
0.76
1.2
1.2
0.32
0.28
g/l
0.89
17
127
9
53
1.70
0.75
1.0
1.2
—
—
—
0
0
47
378
1.25
0.74
1.0
1.0
—
—
—
0
0
7
40
1.75
0.71
1.3
1.1
419.86
341.03
pmol/l
—
7
29
29
222
1.31
0.68
1.8
1.4
—
—
—
0
0
15
103
1.46
0.65
1.5
1.2
—
—
—
0
0
27
208
1.30
0.62
1.2
1.2
—
—
—
0
0
13
88
1.48
0.60
1.8
1.3
—
—
—
0
0
8
52
1.54
0.59
1.1
1.1
—
—
—
0
0
163
1789
0.91
0.59
1.1
1.2
—
—
—
0
0
26
201
1.30
0.58
2.8
2.8
39169.85
39007.95
ug/l
0.02
26
201
14
98
1.43
0.56
1.0
1.0
—
—
—
0
0
6
37
1.62
0.55
1.0
1.1
—
—
—
0
0
34
275
1.24
0.55
1.1
1.2
—
—
—
0
0
34
275
1.24
0.55
1.1
1.2
—
—
—
0
0
22
168
1.31
0.55
1.4
1.2
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
34
276
1.23
0.54
1.1
1.2
—
—
—
0
0
34
276
1.23
0.54
1.1
1.2
—
—
—
0
0
27
213
1.27
0.54
1.4
1.5
—
—
—
0
0
2778
27515
1.05
0.53
4.4
4.1
—
—
—
0
0
6
39
1.54
0.53
1.7
1.5
—
—
—
0
0
34
277
1.23
0.52
1.1
1.2
—
—
—
0
0
29
232
1.25
0.52
1.9
1.6
—
—
—
0
0
16
117
1.37
0.52
1.0
1.2
119.06
104.63
%
1.57
16
111
40
332
1.21
0.52
5.7
5.7
318.79
371.25
umol/l
1.95
34
282
6
98
0.61
0.52
1.7
2.1
129.33
159.07
nmol/l
—
6
85
350
3699
0.94
0.51
1.5
1.4
—
—
—
0
0
11
75
1.47
0.50
2.4
1.8
—
—
—
0
0
11
75
1.47
0.50
2.4
1.8
—
—
—
0
0
7
46
1.52
0.48
1.0
1.0
19.90
23.89
u/ml
—
7
35
22
172
1.28
0.48
1.7
1.5
—
—
—
0
0
11
76
1.45
0.48
2.4
1.8
—
—
—
0
0
18
137
1.32
0.47
2.5
3.2
387.00
177.83
umol/l
—
8
76
68
771
0.88
0.46
1.0
1.1
3.03
5.99
u/ml
1.58
33
321
33
273
1.21
0.46
1.9
2.2
1.42
1.31
mmol/l
0.60
33
268
34
285
1.19
0.42
1.6
1.6
—
—
—
0
0
8
57
1.40
0.42
1.5
1.8
—
118.00
—
0
17
28
231
1.21
0.41
16.6
13.4
839.71
846.06
nmol/l
0.02
28
223
10
71
1.41
0.39
1.0
1.1
—
—
—
0
0
14
106
1.32
0.39
1.1
1.1
—
—
—
0
0
9
68
1.32
0.37
1.0
1.0
—
—
—
0
0
16
125
1.28
0.37
1.0
1.0
—
—
—
0
0
13
99
1.31
0.35
4.9
4.1
—
—
—
0
0
6
43
1.40
0.35
1.5
1.1
—
—
—
0
0
10
73
1.37
0.34
1.1
1.2
—
—
—
0
0
54
604
0.89
0.33
1.2
1.2
—
—
—
0
0
24
202
1.19
0.31
1.6
1.7
48.07
48.43
%
0.01
15
120
45
404
1.12
0.27
1.3
1.7
—
—
—
0
0
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
9
73
1.23
0.25
1.0
1.1
—
—
—
0
0
252
2424
1.04
0.25
1.4
1.3
219.28
239.38
miu/ml
0.43
125
1268
13
159
0.82
0.24
1.4
1.8
—
1885189.37
—
0
16
17
142
1.20
0.24
1.5
2.3
20.48
211.74
ug/l
0.72
17
133
12
96
1.25
0.24
2.3
1.7
—
—
—
0
0
12
96
1.25
0.24
2.3
1.7
—
—
—
0
0
11
87
1.27
0.24
2.1
5.7
—
59.08
—
0
13
20
171
1.17
0.23
1.8
1.2
68.00
66.76
umol/l
0.06
20
171
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
8
105
0.76
0.21
2.8
2.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
17
145
1.17
0.20
1.4
1.7
40.89
43.77
%
0.10
12
86
89
839
1.06
0.20
1.1
1.1
3.30
5.21
u/ml
0.73
52
404
26
231
1.13
0.19
1.1
1.7
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
258
2501
1.03
0.19
1.4
1.4
—
—
—
0
0
29
260
1.12
0.19
1.0
1.1
—
—
—
0
0
376
3670
1.03
0.18
1.4
1.4
—
—
—
0
0
89
939
0.95
0.18
1.1
1.1
0.26
1.19
u/ml
3.12
31
396
7
59
1.19
0.18
1.3
1.3
—
—
—
0
0
97
922
1.05
0.17
1.4
1.3
—
—
—
0
0
712
7009
1.02
0.17
1.5
1.5
—
—
—
0
0
8
73
1.10
0.15
1.0
1.1
—
—
—
0
0
19
168
1.13
0.15
1.4
1.6
144.89
132.52
%
0.25
19
156
12
140
0.86
0.15
1.3
1.5
3.67
3.39
u/field
—
6
101
12
140
0.86
0.15
1.8
1.8
—
—
—
0
0
84
801
1.05
0.14
2.0
1.9
—
—
—
0
0
241
2349
1.03
0.14
1.5
1.4
—
—
—
0
0
159
1641
0.97
0.14
2.3
2.2
—
—
—
0
0
27
295
0.91
0.14
2.0
1.9
—
—
—
0
0
8
98
0.82
0.13
1.3
1.1
95.88
92.03
%
—
8
98
105
1010
1.04
0.13
1.3
1.2
—
—
—
0
0
376
3693
1.02
0.13
1.4
1.4
—
—
—
0
0
16
142
1.13
0.12
1.8
1.9
105.38
106.14
mmol/l
0.20
16
142
16
142
1.13
0.12
1.8
1.9
3.74
3.91
mmol/l
1.28
16
142
375
3685
1.02
0.12
1.4
1.4
—
—
—
0
0
376
3696
1.02
0.12
1.4
1.5
—
—
—
0
0
96
996
0.96
0.12
1.1
1.1
1.46
6.30
u/ml
10.64
46
542
36
337
1.07
0.11
1.2
1.4
—
—
—
0
0
5
45
1.11
0.09
1.2
1.2
—
—
—
0
0
12
135
0.89
0.09
1.3
1.1
—
—
—
0
0
5
47
1.06
0.09
1.4
3.1
—
—
—
0
0
5
47
1.06
0.09
1.4
3.1
—
—
—
0
0
13
116
1.12
0.09
1.5
1.7
2.32
2.45
mg/l
0.20
13
110
15
137
1.10
0.07
1.8
2.2
6.53
9.90
mg/l
—
10
115
8
78
1.03
0.07
1.3
1.4
—
—
—
0
0
115
1125
1.02
0.07
1.2
1.1
1.38
2.62
u/ml
1.40
66
560
94
963
0.98
0.06
1.1
1.1
0.71
1.92
u/ml
4.04
58
476
61
592
1.03
0.06
1.2
1.2
—
—
—
0
0
394
3976
0.99
0.06
1.4
1.5
—
—
—
0
0
18
168
1.07
0.06
1.0
1.0
—
—
—
0
0
335
3380
0.99
0.05
1.5
1.6
—
—
—
0
0
15
161
0.93
0.05
1.3
1.9
1.17
2.46
u/field
—
6
85
14
130
1.08
0.04
1.2
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
14
150
0.93
0.04
1.0
1.1
—
—
—
0
0
10
92
1.09
0.03
1.1
1.1
—
—
—
0
0
12
128
0.94
0.02
1.1
1.8
—
—
—
0
0
96
968
0.99
0.01
1.3
1.5
—
—
—
0
0
38
373
1.02
0.01
1.4
2.3
—
—
—
0
0
57
563
1.01
0.01
1.1
1.1
—
—
—
0
0
20
194
1.03
0.00
1.1
1.2
1.58
1.59
g/l
0.07
20
194
13
132
0.98
0.00
1.2
1.2
—
—
—
0
0
11
109
1.01
0.00
1.3
1.4
—
—
—
0
0
15
146
1.03
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
9.15
—
0
6
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
32.82
—
0
6
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
5.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
19.87
—
0
6
7
72
0.97
-0.00
1.7
1.5
9.26
7.67
ug/l
—
7
72
9
93
0.97
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.3
1.6
—
—
—
0
0
8
86
0.93
-0.00
1.3
1.3
—
—
—
0
0
8
80
1.00
-0.00
1.3
1.4
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
54
0.93
-0.00
2.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
62
0.97
-0.00
1.3
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3.00
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint E4_OVARDYS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_OVARDYS | 1.99 [1.65, 2.4] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.284 |
During the follow-up period (1.1.1998 — 31.12.2019), 243 out of 12980 females with E4_OVARDYS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have E4_OVARDYS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.18% | No data |
| 5 | 1.088% | No data |
| 10 | 2.691% | No data |
| 15 | 5.534% | No data |
| 20 | 10.04% | No data |
Relationships between endpoints
↥Index endpoint: E4_OVARDYS – Ovarian dysfunction
GWS hits: 7
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data