ovarian dysfunction: The inability of the ovaries to function.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2703 |
4. Check minimum number of eventsNone |
2703 |
5. Include endpoints |
3268 |
6. Filter based on genotype QC (FinnGen only) |
3268 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E20-E35
- Name in latin
- Dysfunctio ovarialis
Similar endpoints
↥List of similar endpoints to
Ovarian dysfunction
based on the number of shared cases.
Similar with more cases:
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17415 | 17415 | - |
| Only index persons | 16983 | 16983 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.50 | 0.50 | - |
| Only index persons | 0.62 | 0.62 | - |
| Median age at first event (years) | |||
| Whole population | - | 28.41 | - |
| Only index persons | - | 28.30 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3268 | 3268 | - |
| Unadjusted period prevalence (%) | 1.11 | 1.11 | - |
| Median age at first event (years) | 29.66 | 29.66 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2835
- Matched controls
- 28349
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E28.3
ICD-10 Finland
Primary ovarian failure
385.3
323.0
336
10
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
553.4
323.0
1890
102
121
Kela drug reimbursment
Severe hypofunction of sexual glands
39.2
323.0
448
135
G03DB01
ATC
dydrogesterone; oral
6.4
323.0
1346
3527
N97.0
ICD-10 Finland
Female infertility associated with anovulation
20.8
323.0
746
478
A10BA02
ATC
metformin; oral
5.9
273.5
905
2095
N91.1
ICD-10 Finland
Secondary amenorrhoea
10.7
212.0
433
468
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.6
128.7
1596
9340
N97.9
ICD-10 Finland
Female infertility, unspecified
3.7
116.0
576
1808
L68.0
ICD-10 Finland
Hirsutism
18.0
115.1
183
108
L02BG04
ATC
letrozole; oral
4.7
111.2
414
991
2564A
ICD-9 Finland
Ovarian dysfunction, Polycystic ovaries
+∞
111.2
106
*
E66.01
ICD-10 Finland
Obesity due to excess calories
3.7
106.7
525
1625
G03GA01
ATC
chorionic gonadotrophin; parenteral
4.2
99.2
417
1117
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
4.9
82.4
287
631
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
4.4
82.0
322
801
E28.8
ICD-10 Finland
Other ovarian dysfunction
403.5
79.3
79
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.3
78.5
1047
5850
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.5
74.5
680
3122
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
12.2
67.2
125
107
G03GB02
ATC
clomifene; oral
5.7
62.6
190
355
25690
ICD-8 Finland
Ovarian dysfunction, Syndroma Stein-Leventhal
+∞
60.6
58
*
G03HB01
ATC
cyproterone and estrogen; systemic
2.2
60.0
720
3736
25610
ICD-8 Finland
Ovarian dysfunction, Hypofunction
+∞
59.6
57
*
E66.8
ICD-10 Finland
Other obesity
3.5
59.3
305
951
G03GA06
ATC
follitropin beta; parenteral
4.3
58.7
230
566
G03FB08
ATC
dydrogesterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
3.8
57.9
265
750
G03GA02
ATC
human menopausal gonadotrophin; parenteral
4.1
55.3
227
583
E28.9
ICD-10 Finland
Ovarian dysfunction, unspecified
270.8
52.3
53
*
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.9
48.9
329
1232
G03DA04
ATC
progesterone; systemic, rectal, vaginal
4.1
48.8
200
512
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
3.6
48.3
233
687
TLW00
NOMESCO Finland
Insemination
4.0
48.2
203
533
E28.1
ICD-10 Finland
Ovarian dysfunction: Androgen excess
+∞
48.0
46
*
G03DA02
ATC
medroxyprogesterone; systemic (pregnen (4) derivatives)
3.2
47.1
263
865
E66.00
ICD-10 Finland
Metabolic syndrome
4.4
46.8
179
429
E22.1
ICD-10 Finland
Hyperprolactinaemia
64.9
44.3
51
8
G03GA05
ATC
follitropin alfa; parenteral
3.1
43.6
254
863
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.5
43.1
391
1736
T90
ICPC
Diabetes non-insulin dependent
2.6
41.8
336
1395
C03DA01
ATC
spironolactone; oral
3.6
41.2
199
586
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.7
40.0
300
1196
G03FB06
ATC
medroxyprogesterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
3.6
39.6
187
541
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.3
38.2
391
1840
103
Kela drug reimbursment
Diabetes, insulin-treated
2.3
37.7
394
1872
E28.0
ICD-10 Finland
Ovarian dysfunction: Estrogen excess
+∞
37.6
36
*
Z31.2
ICD-10 Finland
In vitrofertilization
6.5
36.8
98
155
N91.2
ICD-10 Finland
Amenorrhoea, unspecified
7.4
35.8
87
121
E66.9
ICD-10 Finland
Obesity, unspecified
3.4
34.8
178
548
N97.8
ICD-10 Finland
Female infertility of other origin
3.4
33.0
169
521
G03DC02
ATC
norethisterone; oral
2.3
32.7
318
1452
LCA06
NOMESCO Finland
Biopsy of endometrium
2.0
31.9
441
2355
H01CC01
ATC
ganirelix; parenteral
2.9
31.0
199
719
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
30.9
947
6578
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
2.3
30.5
320
1514
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
30.4
591
3571
H03AA01
ATC
levothyroxine sodium; systemic
1.8
29.5
668
4236
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.8
29.5
575
3472
G47.3
ICD-10 Finland
Sleep apnoea
2.1
29.0
361
1842
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
28.7
1144
8469
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
28.5
745
4926
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
28.2
27
*
N91.5
ICD-10 Finland
Oligomenorrhoea, unspecified
6.8
28.0
71
106
A02BC02
ATC
pantoprazole; systemic
1.6
27.9
1504
11948
H02AB09
ATC
hydrocortisone; systemic
5.7
27.8
81
145
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
7.4
27.7
67
93
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
27.6
343
1748
TLW12
NOMESCO Finland
Insertion of frozen embryo
3.3
27.2
141
439
JAH01
NOMESCO Finland
Laparoscopy
2.6
26.9
203
809
N02AX02
ATC
tramadol; systemic, rectal
1.6
26.9
856
5953
G03FB05
ATC
norethisterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
2.6
26.8
212
869
XLA10
NOMESCO Finland
NA
2.7
26.3
191
743
1413
FHL
Laparoscopy and other therapeutic procedure
4.5
26.3
96
221
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
26.3
656
4263
N97.4
ICD-10 Finland
Female infertility associated with male factors
3.2
26.2
144
469
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
26.1
331
1697
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
26.1
25
*
B01AB05
ATC
enoxaparin; parenteral
1.7
25.8
603
3841
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.9
25.7
427
2433
Z31.1
ICD-10 Finland
Artificial insemination
7.5
25.6
61
83
SPAT1262
SPAT
Handing over of treatment supplies
2.0
25.6
340
1780
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.9
25.3
402
2250
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
25.2
560
3506
X05
ICPC
Menstruation absent/scanty
3.6
24.1
113
326
N91.3
ICD-10 Finland
Primary oligomenorrhoea
11.7
23.9
44
38
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
23.4
527
3304
C07AB07
ATC
bisoprolol; oral
1.6
22.7
646
4326
N91.0
ICD-10 Finland
Primary amenorrhoea
11.5
22.7
42
37
T82
ICPC
Obesity
2.7
22.7
162
625
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
22.5
431
2570
H01CA02
ATC
nafarelin; nasal
2.6
21.9
164
649
A10BK03
ATC
empagliflozin; oral
3.1
21.9
124
411
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
21.7
361
2049
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
21.1
166
675
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.6
21.0
95
267
G03GA04
ATC
urofollitropin; parenteral
6.4
20.8
55
88
N02BE01
ATC
paracetamol; systemic, rectal
1.6
20.7
2270
20398
LA2HE
NOMESCO Finland
Repeated measurement of ovarian cyst
4.2
20.4
78
189
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.6
20.4
631
4307
J02AC01
ATC
fluconazole; systemic
1.5
20.3
1408
11472
6280A
ICD-9 Finland
Infertility, female, Associated with anovulation[STERILITAS ET INFERTILITAS ANOVULATORIA PRIM]
27.2
20.0
27
10
N03AX12
ATC
gabapentin; oral
1.9
19.9
330
1868
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
19.8
19
*
25691
ICD-8 Finland
NA
+∞
19.8
19
*
R51.80
ICD-10 Finland
Headache
1.7
19.7
522
3410
L02AE01
ATC
buserelin; implant, nasal, parenteral
4.1
19.6
78
196
N05AH04
ATC
quetiapine; oral
1.6
19.5
514
3358
SPAT1263
SPAT
Sampling
1.4
19.4
1223
9744
E66
ICD-10 Finland
Obesity
2.4
19.2
164
699
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
18.9
610
4193
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
18.9
396
2418
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
18.8
212
1033
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
18.8
18
*
25699
ICD-8 Finland
Ovarian dysfunction, Other and unspecified
+∞
18.8
18
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
18.7
260
1381
N06AX16
ATC
venlafaxine; oral
1.7
18.7
458
2930
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.7
18.3
851
10894
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.2
17.9
182
846
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
17.8
118
436
H02AA02
ATC
fludrocortisone; oral
26.9
17.8
24
9
LBF00
NOMESCO Finland
Perfusion of Fallopian tube
6.5
17.8
46
72
H02AB06
ATC
prednisolone; systemic
1.4
17.7
1062
8335
J01DB01
ATC
cefalexin; oral
1.5
17.4
2264
20540
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
17.4
323
1897
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.6
17.1
128
507
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.0
17.0
218
1118
A02BC01
ATC
omeprazole; systemic
1.5
16.9
584
4069
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
16.8
208
1052
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.0
16.8
96
323
E28
ICD-10 Finland
Ovarian dysfunction
63.7
16.7
19
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
16.7
761
5639
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.6
16.6
489
3276
N06AB04
ATC
citalopram; systemic
1.6
16.6
560
3879
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.6
16.6
500
3370
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
16.5
907
6970
M54.5
ICD-10 Finland
Low back pain
1.4
16.5
885
6769
N06AX21
ATC
duloxetine; oral
1.8
16.5
298
1734
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
16.4
592
4161
N97.1
ICD-10 Finland
Female infertility of tubal origin
3.8
16.3
70
190
WX110
NOMESCO Finland
Local anesthesy
1.4
16.1
2004
17824
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
3.1
16.1
89
293
1410
FHL
Laparoscopy
3.2
16.1
85
271
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
16.1
453
2997
SPAT1301
SPAT
No procedures
1.5
15.9
777
5826
M79.6
ICD-10 Finland
Pain in limb
1.4
15.9
851
6496
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
15.8
762
5694
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
15.6
15
*
25698
ICD-8 Finland
Ovarian dysfunction, Alia definita
+∞
15.6
15
*
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
+∞
15.6
15
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
15.6
241
1328
H01AC01
ATC
somatropin; parenteral
85.6
15.6
17
*
UJF32
NOMESCO Finland
Coloscopy
1.6
15.4
423
2776
L03
ICPC
Low back symptom/complaint
1.5
15.4
653
4751
A02BC05
ATC
esomeprazole; systemic
1.4
15.4
861
6623
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
9.8
15.2
30
31
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
15.0
178
883
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
15.0
260
1490
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
14.8
278
1637
N03AX16
ATC
pregabalin; oral
1.6
14.7
460
3120
R03AC02
ATC
salbutamol; inhalant
1.4
14.6
1455
12342
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
14.6
14
*
N02AA05
ATC
oxycodone; systemic
2.0
14.6
179
903
205
Kela drug reimbursment
Chronic hypertension
1.9
14.5
211
1138
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
7.6
14.4
33
44
N06AB10
ATC
escitalopram; oral
1.5
14.3
680
5050
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.9
14.3
85
296
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
4.2
14.3
53
127
A10BH01
ATC
sitagliptin; oral
2.6
14.2
105
417
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
14.0
77
255
G03FA01
ATC
norethisterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
1.9
13.9
203
1094
P01AB01
ATC
metronidazole; oral, rectal
1.4
13.9
1083
8794
TLW10
NOMESCO Finland
Transfer of fresh embryo
2.5
13.9
110
453
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.2
13.9
142
662
SPAT1310
SPAT
Counselling related to known health issue
1.4
13.8
857
6694
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
13.7
128
572
R06.0
ICD-10 Finland
Dyspnoea
1.5
13.7
459
3158
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
13.6
159
786
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
13.6
262
1553
A02BC03
ATC
lansoprazole; oral
1.5
13.6
534
3807
LAA97
NOMESCO Finland
Other laparoscopic puncture of ovary
75.5
13.6
15
*
TLW20
NOMESCO Finland
Medical ovulation induction
8.4
13.5
29
35
E23.05
ICD-10 Finland
Lack of TSH
140.7
13.5
14
*
G03FB09
ATC
levonorgestrel and estrogen; systemic (progestogens and estrogens, sequential prep.)
4.4
13.4
48
111
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
13.4
447
3075
N06AB03
ATC
fluoxetine; oral
1.6
13.3
327
2083
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
0.6
13.3
203
3289
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
13.1
608
4486
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
13.1
751
5768
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.8
13.0
227
1302
SPAT1153
SPAT
Removal of sutures
1.5
13.0
582
4263
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
12.9
1495
12875
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
13.0
12.9
22
17
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.8
12.8
209
1171
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
12.8
292
1820
M79.1
ICD-10 Finland
Myalgia
1.6
12.7
372
2478
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
12.7
177
939
WX002
NOMESCO Finland
Sedation and analgesia
1.6
12.6
342
2232
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
12.5
829
6517
J01FF01
ATC
clindamycin; systemic
1.4
12.5
595
4402
LAC21
NOMESCO Finland
Laparoscopic destruction of lesion of ovary
3.2
12.5
65
207
G03HA01
ATC
cyproterone; systemic
17.4
12.5
19
11
G03DB02
ATC
megestrol; oral (pregnadien derivatives)
3.2
12.4
65
208
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
12.4
321
2068
N05CF01
ATC
zopiclone; oral
1.5
12.4
569
4181
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
12.4
293
1843
LA2JE
NOMESCO Finland
Follow-up of menstrual cycle with repeated measurement of ovarian cyst
4.3
12.3
45
107
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
12.2
1161
9670
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
12.2
403
2756
S18
ICPC
Laceration/cut
1.4
12.2
773
6031
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
12.2
895
7159
C08CA01
ATC
amlodipine; oral
1.6
12.1
326
2120
8113
FHL
Fractional scraping
2.7
11.8
82
315
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.7
1544
13478
W12
ICPC
Contraception intrauterine
0.7
11.6
295
4282
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
11.6
866
6936
C03CA01
ATC
furosemide; systemic
1.7
11.5
224
1335
Z31.3
ICD-10 Finland
Other assisted fertilization methods
5.7
11.5
32
57
B02AA02
ATC
tranexamic acid; systemic
1.5
11.4
465
3332
M01AE02
ATC
naproxen; oral, rectal
1.3
11.4
1574
13801
R5140
NOMESCO Finland
Monitoring the use of the aid
2.0
11.2
137
692
X07
ICPC
Menstruation irregular/frequent
2.4
11.1
91
382
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
2.2
11.1
108
495
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.4
11.1
89
372
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
11.0
216
1291
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
10.9
494
3615
UKC02
NOMESCO Finland
Cystoscopy
1.9
10.9
165
905
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
10.8
247
1542
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
5.2
10.7
32
62
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.0
10.7
133
676
Z31.6
ICD-10 Finland
General counselling and advice on procreation
3.1
10.7
58
192
J01FA06
ATC
roxithromycin; oral
1.3
10.7
947
7762
A10BJ06
ATC
semaglutide; parenteral
2.9
10.6
63
221
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
10.6
460
3335
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
5.1
10.6
32
63
SPAT1254
SPAT
Administration of medicine
1.6
10.5
303
2008
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
10.5
307
2038
N05BA04
ATC
oxazepam; oral
1.4
10.5
604
4616
C09AA05
ATC
ramipril; oral
1.7
10.5
198
1169
G02CB03
ATC
cabergoline; oral (prolactine inhibitors)
5.0
10.5
32
64
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
10.4
393
2767
102
Kela drug reimbursment
Diabetes insipidus
+∞
10.4
10
*
E30.09
ICD-10 Finland
Delayed puberty NOS
+∞
10.4
10
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
+∞
10.4
10
*
WX704
NOMESCO Finland
Intubation
1.8
10.4
163
905
R11
ICD-10 Finland
Nausea and vomiting
1.7
10.4
212
1279
N06AX11
ATC
mirtazapine; oral
1.4
10.3
731
5782
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.3
1053
8802
R02
ICPC
Shortness of breath/dyspnoea
1.6
10.3
245
1545
M79.7
ICD-10 Finland
Fibromyalgia
2.1
10.2
119
591
M01AH02
ATC
rofecoxib; oral
1.8
10.1
177
1021
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
4.8
10.1
32
67
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
10.0
1402
12215
D07AC01
ATC
betamethasone; topical
1.3
10.0
737
5858
G03FA12
ATC
medroxyprogesterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
2.3
10.0
88
387
E66.0
ICD-10 Finland
Obesity due to excess calories
4.6
10.0
33
72
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.9
1357
11782
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.3
9.9
89
392
A10AE04
ATC
insulin glargine; parenteral
1.9
9.9
138
736
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.3
9.9
48
147
M02AA07
ATC
piroxicam; topical
1.4
9.9
619
4790
H01
ICPC
Ear pain/earache
1.5
9.9
345
2387
SPAT1240
SPAT
Therapeutic discussion
1.5
9.9
424
3066
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
9.8
135
716
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.4
9.8
572
4373
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
9.8
307
2075
SGA01
NOMESCO Finland
Tooth opening as first aid
1.4
9.8
461
3391
C10AA01
ATC
simvastatin; oral
1.6
9.8
292
1952
W15
ICPC
Infertility/subfertility female
2.8
9.7
62
228
B03BA03
ATC
hydroxocobalamin; parenteral
2.5
9.7
76
313
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
9.7
376
2659
A10BJ02
ATC
liraglutide; parenteral
3.5
9.7
43
123
L02AE03
ATC
goserelin; implant
3.7
9.7
41
113
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.7
1066
8982
N06AB06
ATC
sertraline; oral
1.5
9.6
331
2284
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
9.6
444
3253
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
9.6
170
982
M03BX02
ATC
tizanidine; oral
1.3
9.6
1588
14114
C10AA05
ATC
atorvastatin; oral
1.5
9.5
303
2054
N80.9
ICD-10 Finland
Endometriosis, unspecified
2.1
9.5
109
541
WX725
NOMESCO Finland
Noninvasive ventilation
2.2
9.4
94
437
R09
ICPC
Sinus symptom/complaint
1.6
9.4
278
1852
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.7
9.4
211
1308
106
Kela drug reimbursment
Hypoparathyroidism
+∞
9.4
9
*
E34.35
ICD-10 Finland
Abnormal growth retardation
+∞
9.4
9
*
E
ICD-9 Finland
NA
6.2
9.4
24
39
L68.9
ICD-10 Finland
Hypertrichosis, unspecified
12.4
9.3
16
13
R50.9
ICD-10 Finland
Fever, unspecified
1.5
9.3
311
2135
L02AE02
ATC
leuprorelin; implant, parenteral
2.4
9.3
76
321
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
9.3
380
2721
K02.1
ICD-10 Finland
Caries of dentine
1.3
9.2
1682
15101
AA1AD
NOMESCO Finland
CT of head and brain
1.5
9.2
297
2019
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
3.4
9.2
43
129
62400
ICD-8 Finland
Malposition of uterus, Retroversion and retroflexion
13.7
9.2
15
11
SPAT1312
SPAT
General health counselling
1.3
9.2
919
7628
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
1.8
9.1
148
831
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.6
9.1
261
1727
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
9.1
375
2690
N06AX12
ATC
bupropion; oral
1.6
9.1
225
1433
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
9.1
169
992
L17
ICPC
Foot/toe symptom/complaint
1.4
9.0
518
3944
N05CF02
ATC
zolpidem; oral
1.4
9.0
399
2900
A02BA02
ATC
ranitidine; systemic
1.5
9.0
297
2030
N83.1
ICD-10 Finland
Corpus luteum cyst
2.5
8.9
68
277
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
8.9
398
2897
R05
ICPC
Cough
1.4
8.9
564
4369
N03AX09
ATC
lamotrigine; oral
1.7
8.9
166
980
R4190
NOMESCO Finland
Nutritional therapy
2.2
8.8
85
392
R53
ICD-10 Finland
Malaise and fatigue
1.4
8.8
496
3768
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
3.2
8.8
43
134
G44.2
ICD-10 Finland
Tension-type headache
1.4
8.7
397
2897
C07AB02
ATC
metoprolol; systemic
1.6
8.7
231
1499
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.6
8.7
37
103
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
2.5
8.7
67
276
104
Kela drug reimbursment
Thyroid insufficiency
1.9
8.7
131
719
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
3.2
8.6
44
141
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
8.6
117
618
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
8.6
67
278
J01MA12
ATC
levofloxacin; systemic
1.5
8.6
283
1931
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
8.6
280
1906
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
3.0
8.6
49
167
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
8.6
217
1391
M25.5
ICD-10 Finland
Pain in joint
1.3
8.5
706
5693
J01AA02
ATC
doxycycline; systemic
1.3
8.5
1816
16535
D01
ICPC
Abdominal pain/cramps general
1.5
8.5
331
2344
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
27.6
8.5
11
*
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.4
8.4
69
294
N05BA01
ATC
diazepam; systemic, rectal
1.6
8.4
240
1585
Z30.4
ICD-10 Finland
Surveillance of contraceptive drugs
0.7
8.4
219
3177
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
8.4
177
1080
SPAT1283
SPAT
Restricted health certificate
1.3
8.4
800
6577
LCD00
NOMESCO Finland
Hysterectomy
2.1
8.4
87
413
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
90.3
8.4
9
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.7
8.3
161
958
E30.1
ICD-10 Finland
Precocious puberty
+∞
8.3
8
*
2561A
ICD-9 Finland
Ovarian dysfunction, Other ovarian hyperfunction
+∞
8.3
8
*
E27.0
ICD-10 Finland
Other adrenocortical overactivity
+∞
8.3
8
*
E27.2
ICD-10 Finland
Addisonian crisis
+∞
8.3
8
*
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
+∞
8.3
8
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.0
8.3
100
506
R05FB02
ATC
cough suppressants and expectorants
1.3
8.3
701
5666
C08CA05
ATC
nifedipine; systemic
2.0
8.3
100
507
F32.1
ICD-10 Finland
Moderate depressive episode
1.6
8.3
208
1333
Z71.8
ICD-10 Finland
Other specified counselling
1.3
8.3
685
5519
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
8.2
1608
14454
L04AA01
ATC
[U] ciclosporin; systemic
3.8
8.2
33
88
A07AA02
ATC
nystatin; oral
2.0
8.2
101
516
A12AA04
ATC
calcium carbonate; oral
6.5
8.2
20
31
J01CA08
ATC
pivmecillinam; oral
1.3
8.2
1366
12049
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.1
184
1146
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
8.1
456
3454
F43.1
ICD-10 Finland
Post-traumatic stress disorder
1.9
8.1
113
604
SPAT1097
SPAT
Recording of ECG
1.6
8.1
192
1212
UDC00
NOMESCO Finland
Ear microscopy
1.8
8.1
145
846
C09CA06
ATC
candesartan; oral
1.4
8.1
363
2644
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.0
8.0
104
539
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
8.0
272
1868
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
8.0
141
817
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
8.0
116
627
K10.3
ICD-10 Finland
Alveolitis of jaws
1.7
8.0
149
876
SGA03
NOMESCO Finland
Demanding opening and dilatation of root canal of tooth
1.5
8.0
263
1797
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.9
8.0
46
159
SPAT1229
SPAT
Assessment of need for aid
2.0
8.0
95
479
G02BA03
ATC
plastic IUD with progestogen
0.7
8.0
275
3793
L12
ICPC
Hand/finger symptom/complaint
1.4
8.0
332
2381
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.6
7.9
221
1451
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
7.9
865
7234
W85
ICPC
Gestational diabetes
1.5
7.9
234
1562
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.0
7.9
101
525
P06
ICPC
Sleep disturbance
1.5
7.9
254
1727
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
7.8
613
4895
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
5.7
7.8
21
37
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
7.8
128
725
M01AB05
ATC
diclofenac; systemic, rectal
1.3
7.8
1548
13900
N04BC06
ATC
cabergoline; oral (dopamine agonists)
8.5
7.8
16
19
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
7.8
252
1715
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
7.8
611
4879
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
2.8
7.8
47
170
J01EA01
ATC
trimethoprim; systemic
1.3
7.8
687
5579
N06AB05
ATC
paroxetine; oral
1.7
7.7
162
986
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
7.7
155
936
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
5.6
7.7
21
38
L15
ICPC
Knee symptom/complaint
1.4
7.7
402
3010
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
7.6
166
1022
C09CA01
ATC
losartan; oral
1.5
7.6
240
1625
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
1.6
7.6
182
1150
ACC51
NOMESCO Finland
Release of median nerve
1.7
7.6
149
891
N80.1
ICD-10 Finland
Endometriosis of ovary
1.8
7.6
130
748
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.5
7.6
292
2064
E21.0
ICD-10 Finland
Primary hyperparathyroidism
25.1
7.6
10
*
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.0
7.6
92
468
D06
ICPC
Abdominal pain localized other
1.5
7.6
239
1618
J01FA10
ATC
azithromycin; systemic
1.2
7.6
1719
15653
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.2
7.6
69
312
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
2.0
7.6
94
482
SGC10
NOMESCO Finland
Covering pulpa of tooth
1.5
7.5
295
2091
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.5
371
2752
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.7
7.5
161
989
G03DC03
ATC
lynestrenol; oral
2.0
7.4
89
451
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
80.3
7.4
8
*
R13
ICD-10 Finland
Dysphagia
1.9
7.4
97
508
C08CA13
ATC
lercanidipine; oral
1.8
7.4
113
628
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
7.3
593
4749
25899
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Other and unspecified diseases of endocrine system
+∞
7.3
7
*
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
+∞
7.3
7
*
E23.03
ICD-10 Finland
Lack of ACTH
+∞
7.3
7
*
25600
ICD-8 Finland
Ovarian dysfunction, Hyperfunction
+∞
7.3
7
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
7.3
177
1124
J01DA01
ATC
[U] cefalexin; systemic
1.2
7.3
1586
14339
E89.4
ICD-10 Finland
Postprocedural ovarian failure
9.4
7.3
14
15
XF404
NOMESCO Finland
Ambulatory ECG
1.8
7.3
121
689
B01AC04
ATC
clopidogrel; oral
2.0
7.2
85
425
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
7.2
195
1270
LCH11
NOMESCO Finland
Pharmacologic abortion
0.6
7.2
97
1627
WX290
NOMESCO Finland
Other blockade of nerve
1.2
7.2
1423
12721
F34.1
ICD-10 Finland
Dysthymia
1.8
7.2
109
603
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
7.1
133
786
R03DC03
ATC
montelukast; oral
1.4
7.1
401
3035
K04.0
ICD-10 Finland
Pulpitis
1.4
7.1
304
2191
O30.0
ICD-10 Finland
Twin pregnancy
2.1
7.1
76
369
6146A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female
4.2
7.1
25
60
SPAT1216
SPAT
Assessment of functional ability
1.6
7.1
190
1238
R96
ICPC
Asthma
1.6
7.0
181
1169
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
7.0
137
820
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.4
7.0
54
225
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
7.0
179
1152
G03FB01
ATC
norgestrel and estrogen; systemic (progestogens and estrogens, sequential prep.)
4.3
7.0
24
56
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
7.0
305
2209
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
7.0
138
828
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.0
2048
19101
A10BK01
ATC
dapagliflozin; oral
2.4
7.0
56
238
P76
ICPC
Depressive disorder
1.5
7.0
229
1563
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
0.7
7.0
410
5218
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.6
7.0
47
183
127
Kela drug reimbursment
Transplant complication
3.8
7.0
27
71
OAB72
NOMESCO Finland
Weight control and weight loss guidance
3.7
6.9
28
76
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.5
6.9
266
1879
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.9
178
1147
A10BG03
ATC
pioglitazone; oral
3.5
6.9
30
87
A01
ICPC
Pain general/multiple sites
1.6
6.9
157
985
SPAT1260
SPAT
Consultation of another employee
1.4
6.8
401
3062
JAL96
NOMESCO Finland
Other excision of lesion of peritoneum
10.9
6.8
12
11
L29.9
ICD-10 Finland
Pruritus, unspecified
2.3
6.8
57
246
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
6.8
88
460
N80.0
ICD-10 Finland
Endometriosis of uterus
2.0
6.8
77
381
P03
ICPC
Feeling depressed
1.4
6.8
357
2674
J20
ICD-10 Finland
Acute bronchitis
1.5
6.8
205
1375
WX722
NOMESCO Finland
PEEP
2.5
6.8
48
191
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
6.8
143
878
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.8
675
5558
A10AE05
ATC
insulin detemir; parenteral
1.9
6.7
96
520
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
6.7
300
2181
N83.0
ICD-10 Finland
Follicular cyst of ovary
2.3
6.7
57
248
SPAT1325
SPAT
Vaccination
1.3
6.7
658
5404
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.3
6.7
58
257
A11CC02
ATC
dihydrotachysterol; oral
22.6
6.7
9
*
QBJ30
NOMESCO Finland
Correction of abdominal apron
2.8
6.6
39
139
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.5
6.6
227
1567
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
6.6
225
1549
M01AH05
ATC
etoricoxib; oral
1.2
6.6
1304
11612
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.9
6.6
87
459
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.7
6.6
133
806
R01AD09
ATC
mometasone; nasal
1.2
6.5
1266
11249
H02AB04
ATC
methylprednisolone; systemic
1.4
6.5
270
1933
M01AG02
ATC
tolfenamic acid; oral, rectal
1.3
6.5
444
3467
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
6.5
102
572
N03AX11
ATC
topiramate; oral
1.9
6.5
90
483
K04.1
ICD-10 Finland
Necrosis of pulp
1.5
6.4
240
1685
XKD00
NOMESCO Finland
Uroflowmetry
2.0
6.4
79
404
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.8
6.4
39
143
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
70.0
6.4
7
*
E23.2
ICD-10 Finland
Diabetes insipidus
70.0
6.4
7
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.0
6.4
77
393
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
6.4
75
380
Z00.0
ICD-10 Finland
General medical examination
1.4
6.4
393
3019
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
0.8
6.4
508
6222
B81
ICPC
Anaemia vit B12/folate deficiency
2.6
6.4
45
178
C09AA02
ATC
enalapril; systemic
1.6
6.4
163
1054
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.8
6.3
102
575
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
6.3
156
995
A03FA02
ATC
cisapride; oral, rectal
1.8
6.3
108
624
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
8.2
6.3
13
16
WVA20
NOMESCO Finland
Medicine administration
2.6
6.3
43
169
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.8
6.3
104
594
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
6.3
537
4327
W11
ICPC
Contraception oral
0.8
6.3
368
4693
B07.9
ICD-10 Finland
Verruca simplex
1.9
6.3
82
429
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.5
6.3
27
78
SPAT1307
SPAT
Psychosocial counselling and guidance
1.4
6.3
267
1926
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
6.3
133
818
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
6.3
6
*
301
Kela drug reimbursment
Growth hormone
+∞
6.3
6
*
EBA00
NOMESCO Finland
Extraction of tooth
1.2
6.2
823
7003
L08
ICPC
Shoulder symptom/complaint
1.4
6.2
318
2370
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.4
6.2
336
2527
LAE10
NOMESCO Finland
Unilateral oophorectomy
4.8
6.2
19
40
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
2.0
6.2
69
342
J35.0
ICD-10 Finland
Chronic tonsillitis
1.5
6.2
230
1614
N20.1
ICD-10 Finland
Calculus of ureter
2.4
6.2
48
202
T83
ICPC
Overweight
2.2
6.2
56
253
R33
ICD-10 Finland
Retention of urine
2.2
6.2
56
253
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
6.2
652
5400
T89
ICPC
Diabetes insulin dependent
1.9
6.1
89
485
G02CB01
ATC
bromocriptine; systemic
2.1
6.1
66
322
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.5
6.1
192
1300
N92.5
ICD-10 Finland
Other specified irregular menstruation
1.6
6.1
141
889
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
6.1
172
1140
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
6.1
221
1545
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
6.1
457
3619
K04.08
ICD-10 Finland
Other specified pulpit
1.5
6.0
198
1355
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
6.0
202
1386
R51.81
ICD-10 Finland
Facial pain NOS
2.2
6.0
58
271
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.4
6.0
26
76
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
788
1309
7.61
307.65
1.4
1.2
13.4
9.3
u/l
7.06
670
1093
556
544
12.11
307.65
1.5
1.3
1.6
1.6
nmol/l
0.22
491
448
370
303
13.64
307.65
1.3
1.1
6.9
6.0
umol/l
2.69
349
281
203
90
23.98
281.28
1.3
1.0
7.6
5.2
nmol/l
7.58
195
84
769
2406
3.87
210.61
1.7
1.3
287.5
296.9
mu/l
0.33
712
2119
548
1448
4.35
188.31
1.3
1.3
7.9
3.3
ug/l
9.96
478
1387
159
103
16.18
184.81
1.4
1.2
23.2
15.2
pmol/l
5.51
148
91
425
1025
4.62
163.28
1.9
1.4
0.5
0.5
nmol/l
0.41
361
868
778
3007
3.08
147.26
1.5
1.3
18.6
21.9
iu/l
2.00
673
2602
346
902
4.17
118.91
1.6
1.3
14.2
19.5
u/l
3.21
316
763
535
2395
2.48
71.55
2.4
1.7
365.7
391.6
nmol/l
1.78
499
2190
47
20
23.83
65.49
1.0
1.1
—
—
—
0
0
209
631
3.47
57.23
1.4
1.4
29.0
32.0
nmol/l
0.64
193
571
2782
23637
2.19
55.41
5.5
4.2
14.3
14.2
pmol/l
2.16
2650
22134
1794
13265
1.78
55.41
4.4
3.6
6.3
6.1
mmol/l
4.02
1591
11622
2552
21151
1.94
52.49
5.2
3.7
38.0
36.7
mmol/mol
10.34
2445
20013
717
4082
1.97
50.90
4.0
4.1
9.0
12.1
mg/mmol
0.85
460
2656
1536
11113
1.72
48.92
5.0
4.6
9.1
9.3
umol/l
0.66
1440
10378
1229
8398
1.74
47.80
4.4
3.8
36.5
37.0
g/l
2.37
1149
7819
2982
26483
2.44
46.62
6.4
4.8
2.5
1.9
mu/l
0.35
2882
25219
2198
17784
1.72
44.21
6.9
5.9
72.8
70.0
u/l
3.71
2083
16729
2783
24247
2.00
42.69
4.1
3.1
5.7
5.5
mmol/l
12.02
2637
22768
1042
7004
1.72
41.68
2.4
2.3
61.5
54.8
u/l
0.48
973
6472
851
5414
1.77
41.33
3.2
3.2
8.2
7.7
mmol/l
1.56
721
4724
382
1885
2.16
39.28
4.2
4.3
1.1
1.0
mmol/l
1.64
368
1758
1295
9348
1.64
38.71
5.9
4.5
1.2
1.2
mmol/l
0.44
1093
7901
2890
25766
2.05
37.78
12.1
8.3
3.9
3.9
mmol/l
1.32
2804
24866
2883
25715
2.03
37.12
12.0
8.2
139.4
139.4
mmol/l
0.31
2805
24898
1155
8302
1.61
33.95
5.3
4.0
1.2
1.2
mmol/l
0.50
1060
7556
1189
8625
1.60
33.52
3.1
2.7
28.1
27.5
u/l
0.24
1135
8239
1135
8189
1.59
32.49
2.0
1.7
94.9
99.5
pmol/l
2.90
625
4518
1431
10888
1.56
32.48
2.6
2.1
71.2
72.9
nmol/l
1.75
1346
10218
674
4382
1.68
28.81
1.6
1.4
19.8
21.0
nmol/l
1.78
609
3919
970
6913
1.57
28.45
2.8
2.7
2.3
2.3
mmol/l
0.28
867
6246
75
184
4.15
27.68
1.3
1.2
389.6
408.0
mu/l
0.11
75
171
454
2679
1.81
27.28
3.3
2.9
0.8
0.8
mmol/l
0.62
432
2508
76
191
4.05
27.16
1.4
1.2
70.3
72.1
%
0.43
76
178
59
126
4.75
25.93
2.0
1.4
1.1
2.8
nmol/l
0.82
52
89
2254
19399
1.52
25.92
4.7
3.8
448.0
1704.8
e6/l
2.01
33
197
647
4269
1.64
25.79
2.8
2.2
5650.2
6870.0
u/l
0.57
297
1766
892
6384
1.55
25.08
2.3
2.1
2.6
2.6
mg/l
0.07
790
5491
2793
25332
1.71
24.97
4.1
3.3
2.9
2.9
mmol/l
0.60
2660
23986
741
5089
1.59
24.96
2.3
2.0
1500.7
2996.2
umol/l
1.19
667
4543
267
1368
2.04
24.51
1.4
1.4
—
—
—
0
0
782
5487
1.56
23.84
1.7
1.5
1.5
1.3
mmol/l
9.32
694
4817
530
3387
1.67
23.75
1.3
1.2
127.0
154.6
iu/ml
0.84
194
1329
120
450
2.73
22.56
1.1
1.1
9.7
3327.1
iu/ml
0.95
30
143
2752
25026
1.63
22.40
3.9
3.1
1.4
1.5
mmol/l
35.56
2647
23841
2764
25166
1.64
22.34
3.9
3.1
4.7
4.8
mmol/l
0.89
2659
24026
479
3034
1.68
22.09
1.9
1.6
1203.2
1182.3
nmol/l
0.21
402
2345
878
6411
1.51
21.97
2.4
2.4
17.0
24.2
ng/l
0.97
334
2321
2650
23944
1.56
21.50
3.5
2.8
1.4
1.1
mmol/l
39.17
2546
22814
402
2455
1.73
21.17
2.6
2.3
5.0
5.2
umol/l
0.14
335
2010
381
2299
1.74
20.93
3.5
3.3
4.6
4.6
pmol/l
0.23
344
2074
1684
14015
1.42
20.60
4.3
3.8
—
—
—
0
0
456
2908
1.66
20.38
2.0
2.0
2.6
2.5
g/l
2.14
421
2691
475
3066
1.64
20.24
3.0
2.6
142.2
280.8
ng/l
0.93
230
1416
1645
13687
1.41
19.85
5.7
5.7
0.2
0.2
e9/l
0.04
1503
12350
1074
8304
1.44
19.57
1.4
1.3
1.5
1.6
u/ml
0.13
296
2448
1501
12337
1.40
19.22
5.6
5.4
2.6
2.7
%
2.10
1406
11498
618
4320
1.53
18.59
1.7
1.5
8425304.0
36486552.2
pmol/l
1.57
546
3785
1769
14999
1.39
18.56
7.9
7.7
4.1
4.0
e9/l
2.66
1571
13293
2195
19322
1.41
18.34
4.2
3.5
10.4
9.0
mm/h
7.89
2066
18122
1935
16672
1.39
18.33
3.3
2.9
61.0
57.4
ug/l
0.83
1849
15851
1633
13741
1.38
17.52
5.5
5.4
2.1
2.0
e9/l
4.31
1476
12474
402
2576
1.64
17.49
2.2
2.1
21.8
23.8
%
2.25
329
2223
490
3296
1.57
17.42
2.1
2.0
13.7
14.7
umol/l
2.20
453
3056
447
2949
1.60
17.26
2.3
2.5
450.4
561.1
ng/l
0.60
356
2331
3022
28553
1.78
16.64
9.7
7.6
26.9
23.0
u/l
17.45
2955
27699
1541
12916
1.37
16.59
5.4
5.2
56.4
56.4
%
0.03
1442
12162
170
855
2.04
16.40
3.4
2.7
5.1
5.1
kpa
0.03
152
802
1553
13066
1.36
16.16
5.7
5.4
30.3
30.1
%
0.34
1450
12262
1685
14360
1.36
16.11
3.5
3.1
0.0
0.0
estimate
1.79
337
2969
811
6132
1.43
16.11
2.0
1.7
0.7
0.8
mg/l
1.00
600
4441
162
820
2.03
15.36
3.5
2.7
1.1
1.2
mmol/l
0.28
111
570
197
1067
1.90
15.36
3.1
2.7
90.1
65.9
ng/l
0.77
177
954
1669
14275
1.35
15.22
4.7
4.3
0.0
0.0
estimate
0.35
345
3022
1662
14216
1.34
15.10
3.5
3.1
0.0
0.0
estimate
1.15
334
2924
318
2002
1.65
14.76
2.5
2.4
26.3
36.4
u/ml
1.55
307
1939
2951
27880
1.60
14.05
12.7
9.2
17.6
18.4
mg/l
0.79
2452
21263
256
1542
1.72
14.03
2.2
2.1
0.2
0.2
g/l
1.37
240
1453
2626
24251
1.42
13.84
10.0
7.4
97.0
96.2
ml/min/173m2
1.29
2111
19382
414
2829
1.53
13.53
1.9
1.7
—
—
—
0
0
720
5501
1.40
13.08
1.3
1.3
29.2
21.5
iu/ml
0.83
204
1675
111
525
2.15
12.64
3.8
2.8
24.5
24.5
mmol/l
0.05
102
493
352
2373
1.54
12.20
3.6
2.9
30.9
33.4
%
4.41
296
1797
195
1132
1.77
12.18
1.1
1.1
2.4
4.4
u/ml
1.05
22
200
690
5327
1.37
11.60
2.2
1.9
204.7
128.8
u/l
0.40
667
5059
275
1797
1.58
10.92
3.5
3.7
224.1
230.6
u/l
0.31
256
1699
78
340
2.33
10.86
2.7
4.2
305.6
76.3
u/ml
0.64
23
106
269
1762
1.57
10.57
1.8
1.5
—
—
—
0
0
151
850
1.81
10.49
2.6
2.5
76.9
96.3
ng/l
0.73
135
748
2147
19521
1.29
10.46
3.1
2.6
35.3
29.8
u/l
5.53
2067
18725
853
6892
1.32
10.45
1.5
1.4
2.0
2.1
g/l
0.82
512
4423
56
214
2.65
10.32
1.2
1.4
—
—
titre
—
0
0
759
6055
1.33
10.12
3.5
3.3
1.0
1.0
kg/l
0.26
131
913
664
5210
1.34
9.88
1.3
1.3
12.4
8.6
u/ml
0.78
253
2246
270
1803
1.54
9.75
1.8
1.5
—
—
—
0
0
794
6411
1.32
9.66
2.2
1.8
—
—
—
0
0
377
2702
1.45
9.62
2.4
2.0
28.6
29.1
s
1.34
370
2596
434
3194
1.41
9.57
2.4
2.2
2.4
2.4
mmol/l
1.38
366
2764
596
4626
1.35
9.49
2.6
2.2
10.0
9.5
e6/l
0.23
518
3986
207
1308
1.62
9.47
1.7
1.5
—
—
—
0
0
207
1325
1.60
8.99
1.4
1.3
1.7
1.1
u/ml
0.15
14
105
18
35
5.17
8.88
1.2
1.2
—
—
—
0
0
16
29
5.54
8.49
1.3
1.1
12.1
8.4
pmol/l
0.61
11
16
75
360
2.11
8.35
2.2
2.8
1.0
0.8
nmol/l
1.13
59
309
1286
11187
1.25
8.29
3.6
3.1
—
—
—
0
0
745
6073
1.29
8.27
2.9
2.5
0.2
0.3
e6/l
2.23
549
4406
182
1171
1.59
7.77
6.8
6.9
125.1
120.9
g/l
2.50
175
1133
216
1451
1.52
7.62
6.3
6.2
13.0
13.9
kpa
1.93
205
1387
216
1451
1.52
7.62
6.1
6.3
0.6
0.7
mmol/l
0.20
169
1073
308
2220
1.43
7.60
4.6
4.1
—
—
—
0
0
246
1702
1.48
7.53
5.9
5.8
105.1
105.1
mmol/l
0.05
241
1669
215
1451
1.52
7.43
6.3
6.2
5.0
5.0
kpa
0.28
206
1389
387
2917
1.37
7.35
1.9
1.8
—
—
—
0
0
901
7612
1.25
7.33
3.8
3.3
0.0
0.0
estimate
2.12
341
2975
184
1204
1.56
7.32
3.2
3.3
1.7
1.7
mmol/l
0.05
146
960
228
1584
1.47
6.85
3.2
2.5
1.8
1.6
%
2.64
205
1400
61
294
2.10
6.79
3.3
2.6
—
—
—
0
0
128
785
1.66
6.68
6.9
6.2
24.4
24.3
mmol/l
0.30
120
733
137
864
1.61
6.41
2.4
2.4
3.9
3.6
g/l
1.31
132
804
74
391
1.91
6.40
1.3
1.2
—
—
—
0
0
89
500
1.80
6.36
1.2
1.4
—
—
—
0
0
42
181
2.34
6.15
1.0
1.0
91.3
86.4
%
0.59
37
143
81
451
1.82
5.98
1.4
1.3
—
—
—
0
0
155
1024
1.54
5.96
2.3
2.1
—
—
—
0
0
165
1106
1.52
5.94
5.9
5.8
6.7
6.4
mmol/l
0.45
159
1065
88
504
1.77
5.92
5.6
4.1
1.8
1.8
%
0.04
83
469
286
2130
1.38
5.86
2.5
2.2
37.7
35.0
u/l
0.14
237
1799
256
1876
1.40
5.78
2.8
2.4
10.2
10.5
g/l
0.92
232
1734
208
1474
1.44
5.68
3.7
2.4
1.2
1.2
mmol/l
0.24
189
1254
48
228
2.12
5.61
1.5
1.3
435.6
406.0
pmol/l
0.13
42
182
140
918
1.55
5.59
1.4
1.3
41.6
36.1
u/ml
0.10
15
70
136
886
1.56
5.59
2.5
2.1
96.2
94.3
%
0.47
126
801
148
987
1.52
5.48
1.7
2.1
43.4
39.0
u/l
1.63
140
933
128
832
1.56
5.33
1.4
1.3
1.6
11.4
u/ml
3.06
17
149
3207
31581
1.83
5.30
19.2
14.0
4.5
4.5
e12/l
16.40
3156
30960
3208
31597
1.83
5.25
19.3
14.0
133.2
132.6
g/l
3.01
3192
31301
3207
31586
1.82
5.22
19.2
14.0
7.1
6.8
e9/l
8.75
3155
30931
71
397
1.81
5.22
3.6
4.8
208.6
663.0
iu/ml
—
5
37
2595
24792
1.23
5.19
14.8
11.1
13.5
13.4
%
2.65
2557
24320
125
818
1.55
5.07
1.4
1.3
3.4
3.6
u/ml
0.04
13
90
178
1255
1.44
5.02
5.1
5.4
1.3
1.2
mmol/l
0.57
171
1204
187
1346
1.41
4.73
2.2
2.3
4.5
5.0
umol/l
0.56
132
997
3201
31547
1.72
4.67
19.3
14.0
275.1
269.1
e9/l
6.47
3155
30957
50
260
1.94
4.63
1.1
1.1
1.0
1.0
ratio
0.16
16
96
55
296
1.87
4.60
2.8
2.8
33.9
110.5
ug/min
1.63
37
206
63
354
1.79
4.60
2.5
2.4
23.6
24.4
mmol/l
0.89
52
318
550
4624
1.23
4.45
2.2
2.5
107.8
92.9
ug/g
0.54
412
3588
126
852
1.50
4.43
2.6
2.4
167.5
161.5
%
0.38
118
803
64
366
1.76
4.42
1.4
1.2
—
—
—
0
0
64
366
1.76
4.42
1.4
1.2
—
—
—
0
0
41
203
2.03
4.37
6.1
5.7
9.8
6.5
mmol/l
0.49
35
163
49
260
1.90
4.30
1.2
1.1
—
0.4
nmol/l
—
0
5
53
294
1.82
4.07
1.3
1.4
—
—
—
0
0
1098
9891
1.17
4.06
1.9
1.8
—
—
—
0
0
168
1222
1.40
4.04
1.6
1.5
—
—
—
0
0
143
1013
1.43
4.00
2.1
2.2
67.9
67.8
g/l
0.07
135
954
47
253
1.87
3.98
1.3
1.2
—
—
—
0
0
47
254
1.86
3.93
1.3
1.2
—
—
—
0
0
53
299
1.79
3.87
1.3
1.4
—
—
—
0
0
94
618
1.54
3.82
1.8
2.1
9.9
10.3
mg/l
0.16
88
592
29
133
2.19
3.79
1.1
1.2
—
—
—
0
0
136
965
1.43
3.79
1.8
2.2
5.4
4.0
iu/l
0.59
49
406
52
294
1.78
3.78
1.3
1.4
—
—
—
0
0
171
1271
1.36
3.64
2.8
3.5
8.2
41.8
ug/l
0.60
119
901
101
684
1.49
3.59
1.1
1.2
251.9
249.5
u/ml
0.03
59
460
35
177
1.99
3.58
1.7
1.6
—
—
—
0
0
121
852
1.44
3.54
1.7
1.4
—
—
—
0
0
100
679
1.49
3.52
3.2
3.6
24.2
24.0
mmol/l
0.39
90
602
70
441
1.60
3.45
2.8
2.1
227.6
278.8
ug/l
0.16
53
383
50
288
1.75
3.45
1.3
1.4
—
—
—
0
0
50
288
1.75
3.45
1.3
1.4
—
—
—
0
0
50
289
1.74
3.41
1.3
1.4
—
—
—
0
0
105
726
1.46
3.39
1.1
1.2
—
—
—
0
0
33
167
1.99
3.38
1.2
1.1
54.6
62.5
u/l
0.30
23
112
751
6652
1.17
3.36
2.0
1.9
—
—
—
0
0
502
4310
1.19
3.25
1.4
1.5
—
—
—
0
0
62
388
1.61
3.17
2.6
1.9
131.6
130.8
g/l
0.15
54
289
92
629
1.48
3.17
1.3
1.3
104.5
107.4
u/ml
0.11
14
137
1072
9783
1.14
3.15
2.3
2.3
—
—
—
0
0
456
3894
1.20
3.14
1.6
1.6
1.4
1.3
%
4.05
413
3532
969
8785
1.15
3.13
2.2
2.1
—
—
—
0
0
131
959
1.38
3.11
2.9
2.3
0.2
0.2
e6/l
0.41
124
911
38
210
1.82
3.04
1.7
1.5
—
—
—
0
0
120
870
1.39
3.03
2.1
2.0
—
—
—
0
0
35
189
1.86
3.01
2.5
2.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
49
293
1.68
3.00
4.1
4.1
0.4
0.4
u/ml
0.07
34
151
37
204
1.82
2.98
2.4
2.1
9.5
12.0
%
0.62
20
121
14
51
2.75
2.98
2.3
4.7
—
—
—
0
0
81
548
1.49
2.96
1.5
1.3
326.7
325.5
ug/g
0.01
42
251
103
732
1.42
2.92
1.2
1.3
394.0
450.8
mg/l
0.96
97
690
408
3482
1.20
2.83
2.4
2.2
0.8
1.2
e6/l
1.61
212
1852
206
1635
1.28
2.82
1.6
1.6
4.2
3.8
mg/l
0.23
155
1090
273
2242
1.24
2.79
1.1
1.0
—
—
—
0
0
39
225
1.74
2.74
2.1
2.8
1.1
1.5
%
0.33
34
173
2816
27479
1.18
2.71
13.1
9.9
39.7
39.5
%
0.97
2229
22980
89
630
1.42
2.61
1.2
1.4
154.5
6812.8
e6/l
0.60
76
511
89
631
1.42
2.59
1.2
1.4
2.2
20.5
e6/l
4.12
69
482
102
741
1.39
2.59
1.4
1.3
23.1
36.1
u/ml
—
10
71
1075
9914
1.13
2.58
1.6
1.5
—
—
—
0
0
61
402
1.53
2.56
1.8
1.5
—
—
—
0
0
6
11
5.46
2.54
1.0
1.1
—
—
—
0
0
41
246
1.68
2.53
3.4
3.2
20.6
24.2
mg/l
0.73
35
206
64
428
1.51
2.52
2.5
1.8
1.0
2.0
ug/l
0.68
57
384
35
201
1.75
2.52
2.6
2.5
0.2
0.2
e9/l
0.59
30
170
106
783
1.37
2.45
7.0
7.8
0.6
0.7
%
0.88
106
778
42
256
1.65
2.45
1.2
1.2
—
—
—
0
0
380
3267
1.18
2.45
2.7
2.3
5.4
5.2
e6/l
0.12
183
1642
50
320
1.57
2.41
2.2
1.8
16.4
16.8
%
0.31
25
142
6
12
5.01
2.40
1.0
1.3
—
—
—
0
0
78
549
1.43
2.39
1.2
1.2
3.0
3.9
u/ml
0.52
31
228
61
409
1.50
2.39
1.8
1.5
—
—
—
0
0
91
659
1.39
2.38
2.1
2.1
1.4
1.3
g/l
0.72
82
573
5
8
6.26
2.37
1.0
1.0
—
—
—
0
0
5
8
6.26
2.37
1.0
1.3
—
—
—
0
0
279
2340
1.21
2.36
1.4
1.3
110.9
181.5
u/ml
2.05
258
2182
26
140
1.86
2.31
1.7
1.5
—
—
—
0
0
26
140
1.86
2.31
1.7
1.5
—
—
—
0
0
26
140
1.86
2.31
1.7
1.5
—
—
—
0
0
105
783
1.35
2.30
2.0
1.9
—
—
—
0
0
39
238
1.65
2.28
1.5
1.6
—
—
—
0
0
17
79
2.16
2.24
1.1
1.3
—
—
—
0
0
27
149
1.82
2.24
2.0
1.5
5.0
5.2
u/l
0.09
20
125
87
633
1.38
2.23
1.1
1.1
3.2
2.9
u/ml
0.10
40
370
104
779
1.35
2.23
7.1
7.8
1.4
1.4
%
0.01
104
772
50
327
1.54
2.21
1.1
1.1
—
—
—
0
0
13
54
2.41
2.19
2.7
2.6
—
—
—
0
0
42
265
1.59
2.17
1.9
1.5
—
—
—
0
0
230
1911
1.22
2.16
2.7
2.3
—
—
—
0
0
189
1539
1.24
2.15
12.9
10.7
1.1
1.1
inr
0.14
29
291
41
258
1.60
2.15
2.5
2.4
32.4
31.1
umol/l
0.16
35
224
34
204
1.67
2.14
2.5
2.5
669.4
507.1
e6/l
1.80
29
170
17
81
2.10
2.12
1.1
1.3
—
—
—
0
0
127
989
1.30
2.09
2.2
2.0
1.2
1.2
g/l
1.96
121
936
51
340
1.51
2.09
1.0
1.1
195.6
194.9
mg/l
0.02
46
296
124
963
1.30
2.09
2.2
2.0
0.2
0.2
g/l
2.21
118
912
15
69
2.18
2.04
2.5
3.4
64.8
120.3
ng/l
—
10
39
39
246
1.59
2.04
3.5
3.2
32.5
49.8
mg/l
0.45
32
207
52
353
1.48
1.97
1.1
1.1
33.8
34.2
mg/l
0.04
46
289
5
11
4.55
1.94
1.0
1.1
4.2
31.6
u/l
—
5
11
9
33
2.73
1.93
1.1
1.4
—
—
—
0
0
72
524
1.38
1.89
3.0
3.5
4.0
3.9
e9/l
0.10
72
524
29
173
1.68
1.89
1.0
1.1
—
—
—
0
0
162
1319
1.24
1.88
1.5
1.7
—
—
—
0
0
44
293
1.51
1.84
1.2
1.2
—
—
—
0
0
56
392
1.44
1.84
1.2
1.2
—
—
—
0
0
282
2428
1.18
1.84
1.4
1.5
—
—
—
0
0
93
709
1.32
1.83
1.1
1.1
—
—
—
0
0
5
12
4.17
1.82
1.4
2.6
—
—
—
0
0
15
73
2.06
1.80
1.9
2.2
—
—
—
0
0
32
199
1.61
1.80
1.1
1.1
—
—
—
0
0
91
694
1.32
1.79
1.8
1.6
7.1
6.7
mmol/l
0.53
59
491
72
531
1.36
1.77
3.1
3.6
55.9
56.7
%
0.24
72
531
68
499
1.37
1.73
3.7
3.2
15.4
22.4
mg/l
0.84
39
304
7
24
2.92
1.72
2.1
1.4
—
—
—
0
0
192
1610
1.20
1.70
2.7
2.1
74.5
82.3
ml/min/173m2
1.55
68
578
58
416
1.40
1.69
2.1
3.2
569.0
434.1
u/ml
0.08
52
347
26
156
1.67
1.69
1.2
1.1
104.9
93.3
%
0.93
11
59
38
251
1.52
1.68
1.5
1.3
—
—
—
0
0
30
188
1.60
1.65
1.6
1.3
—
—
—
0
0
28
173
1.62
1.63
3.0
2.8
984.8
892.2
e6/l
0.21
14
75
5
14
3.58
1.61
1.2
1.4
615.5
455.6
nmol/l
—
5
14
113
906
1.26
1.55
2.0
2.0
6.3
4.4
ug/l
0.37
102
783
13
64
2.04
1.54
1.1
1.3
—
—
—
0
0
13
64
2.04
1.54
1.1
1.3
—
—
—
0
0
17
93
1.83
1.51
1.4
1.5
1.1
4.9
u/l
—
7
49
14
72
1.95
1.48
1.7
1.2
—
—
—
0
0
37
251
1.48
1.47
1.3
1.1
—
68.3
—
0
7
322
2854
1.14
1.47
2.1
1.8
—
—
—
0
0
22
132
1.67
1.45
1.2
1.1
109.3
108.5
%
0.06
22
112
36
244
1.48
1.44
1.0
1.1
1.1
1.0
u/l
0.29
18
97
71
542
1.32
1.44
1.1
1.1
—
—
—
0
0
26
164
1.59
1.43
1.2
1.1
99.1
93.4
%
0.56
11
61
24
149
1.62
1.41
2.7
2.2
—
—
—
0
0
18
301
0.60
1.40
1.0
1.1
—
—
—
0
0
239
2082
1.16
1.40
2.4
2.3
11.3
20.8
au/ml
1.97
11
175
7
29
2.42
1.39
3.0
1.8
—
—
—
0
0
563
5177
1.11
1.38
1.9
1.8
—
—
—
0
0
6
23
2.61
1.36
1.2
1.2
1.4
1.4
umol/24h
—
6
23
5
17
2.94
1.36
1.6
1.9
—
—
—
0
0
14
77
1.82
1.25
3.2
3.5
—
—
—
0
0
19
115
1.66
1.24
1.0
1.2
—
—
—
0
0
53
398
1.34
1.24
1.4
1.7
10.8
10.3
g/l
0.35
44
358
51
381
1.34
1.23
1.2
1.1
—
—
—
0
0
85
683
1.25
1.20
2.3
2.1
13.3
13.1
%
1.18
85
678
55
418
1.32
1.19
1.4
1.7
3.1
3.1
g/l
0.01
44
346
6
26
2.31
1.18
1.3
2.3
—
—
—
0
0
220
1933
1.15
1.18
1.3
1.3
34.0
29.6
au/ml
—
10
70
15
249
0.60
1.17
1.1
1.2
—
—
—
0
0
48
635
0.75
1.17
1.0
1.1
0.1
0.2
u/ml
—
8
129
14
79
1.78
1.16
1.2
1.2
—
—
—
0
0
72
571
1.27
1.15
1.2
1.2
3.9
3.5
u/ml
0.05
20
203
41
300
1.37
1.14
1.8
1.4
—
—
—
0
0
64
501
1.28
1.13
1.6
1.5
9.8
11.4
mmol/l
0.51
12
45
56
432
1.30
1.11
1.4
1.7
3.6
3.7
g/l
0.20
42
333
56
432
1.30
1.11
1.4
1.7
7.2
7.4
g/l
0.19
44
357
56
432
1.30
1.11
1.4
1.7
—
—
—
0
0
15
88
1.71
1.11
2.5
1.6
—
—
—
0
0
17
104
1.64
1.09
1.9
2.3
13.8
15.6
umol/l
0.35
17
104
31
218
1.43
1.09
1.5
1.4
—
—
—
0
0
34
246
1.39
1.03
1.1
1.2
0.1
0.2
u/ml
1.27
16
72
0
29
0.00
0.97
0.0
3.5
—
—
—
0
0
0
30
0.00
0.97
0.0
3.4
—
22.8
—
0
30
7
36
1.95
0.97
4.0
3.7
—
—
—
0
0
50
389
1.29
0.96
1.4
1.5
—
—
—
0
0
45
345
1.31
0.96
1.2
1.2
—
—
—
0
0
12
69
1.74
0.96
1.1
1.1
—
—
—
0
0
26
182
1.43
0.96
1.1
1.2
—
—
—
0
0
31
225
1.38
0.94
2.2
1.7
17.7
25.5
mg/l
—
6
63
57
453
1.26
0.94
1.3
1.4
—
4304.0
—
0
5
23
158
1.46
0.93
1.5
1.6
31.0
31.8
pg
0.32
23
158
11
63
1.75
0.90
1.1
1.5
—
2339.2
—
0
5
150
1314
1.15
0.89
1.7
1.5
—
—
—
0
0
683
6466
1.07
0.87
1.5
1.5
—
—
—
0
0
46
361
1.28
0.85
1.5
1.8
3392.9
9172.4
e6/l
2.19
30
269
31
230
1.35
0.84
1.1
1.1
1512.0
1506.9
miu/ml
0.01
31
230
13
80
1.63
0.84
1.1
1.0
—
—
—
0
0
8
46
1.74
0.82
2.3
1.4
—
—
—
0
0
6
32
1.88
0.81
1.0
1.0
—
—
—
0
0
34
259
1.32
0.79
1.1
1.2
—
—
—
0
0
34
259
1.32
0.79
1.1
1.2
—
—
—
0
0
6
33
1.82
0.79
1.0
1.0
—
—
—
0
0
16
106
1.51
0.78
1.0
1.2
119.1
105.6
%
1.41
16
101
24
173
1.39
0.78
2.4
2.1
3.3
34.9
nmol/l
0.49
24
166
222
2014
1.11
0.78
1.5
1.5
—
—
—
0
0
34
260
1.31
0.78
1.1
1.2
—
—
—
0
0
34
260
1.31
0.78
1.1
1.2
—
—
—
0
0
28
208
1.35
0.77
1.0
1.1
—
—
—
0
0
20
140
1.43
0.76
2.0
2.7
1665.5
712.6
u/ml
0.71
20
140
34
261
1.31
0.76
1.1
1.2
—
—
—
0
0
15
99
1.52
0.75
1.5
1.1
—
—
—
0
0
122
1070
1.15
0.75
1.4
1.3
—
—
—
0
0
14
91
1.54
0.75
1.0
1.0
—
—
—
0
0
13
83
1.57
0.75
1.8
1.3
—
—
—
0
0
5
24
2.08
0.74
1.0
2.0
—
—
—
0
0
17
116
1.47
0.74
1.1
1.4
—
—
u/ml
—
0
0
7
39
1.80
0.72
1.3
1.1
419.9
352.2
pmol/l
—
7
29
23
168
1.37
0.71
1.3
1.4
—
—
—
0
0
29
221
1.32
0.69
1.9
1.6
—
—
—
0
0
59
491
1.21
0.69
1.5
1.6
—
—
—
0
0
99
863
1.15
0.68
1.2
1.1
—
—
—
0
0
14
94
1.49
0.66
1.1
1.1
—
—
—
0
0
28
214
1.31
0.66
1.8
1.4
—
—
—
0
0
11
70
1.57
0.65
2.4
1.7
—
—
—
0
0
11
70
1.57
0.65
2.4
1.7
—
—
—
0
0
62
732
0.84
0.64
1.0
1.1
3.0
6.0
u/ml
1.40
29
305
363
3404
1.07
0.64
1.4
1.4
—
—
—
0
0
44
359
1.23
0.64
1.0
1.1
—
—
—
0
0
108
954
1.14
0.63
1.6
1.6
22.1
0.4
iu/ml
0.47
16
164
11
71
1.55
0.62
2.4
1.7
—
—
—
0
0
8
50
1.60
0.61
1.1
1.1
—
—
—
0
0
8
51
1.57
0.60
1.0
1.2
—
—
—
0
0
362
3413
1.07
0.56
1.4
1.4
—
—
—
0
0
363
3423
1.07
0.56
1.4
1.4
—
—
—
0
0
31
247
1.26
0.56
1.2
1.1
21.2
7.6
iu/ml
—
8
62
8
55
1.46
0.56
1.5
1.9
—
125.2
—
0
16
10
65
1.54
0.55
1.0
1.1
—
—
—
0
0
363
3426
1.07
0.55
1.4
1.4
—
—
—
0
0
22
168
1.31
0.55
1.7
1.5
—
—
—
0
0
33
267
1.24
0.53
1.9
2.2
1.4
1.3
mmol/l
0.55
33
262
11
74
1.49
0.53
1.0
1.1
—
—
—
0
0
9
62
1.45
0.53
1.0
1.0
—
—
—
0
0
10
66
1.52
0.52
1.1
1.2
—
—
—
0
0
25
196
1.28
0.52
1.2
1.2
—
—
—
0
0
6
96
0.62
0.52
1.7
2.1
129.3
160.7
nmol/l
—
6
84
96
856
1.13
0.51
1.2
1.1
—
—
—
0
0
25
198
1.26
0.49
1.4
1.5
—
—
—
0
0
27
219
1.23
0.45
14.6
13.5
856.0
834.6
nmol/l
0.08
27
212
16
122
1.31
0.42
1.0
1.0
—
—
—
0
0
13
96
1.36
0.41
4.9
4.2
—
—
—
0
0
24
195
1.23
0.40
1.6
1.7
48.1
48.7
%
0.03
15
118
10
137
0.73
0.39
1.9
1.8
—
—
—
0
0
9
66
1.36
0.38
1.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.6
1.4
—
—
—
0
0
336
3515
0.95
0.38
1.5
1.4
—
—
—
0
0
9
67
1.34
0.38
1.0
1.1
—
—
—
0
0
13
98
1.33
0.37
1.2
1.1
—
—
—
0
0
37
318
1.17
0.36
5.6
5.7
313.1
373.6
umol/l
2.17
31
269
234
2217
1.06
0.36
1.5
1.4
—
—
—
0
0
6
44
1.36
0.34
1.3
1.2
—
—
—
0
0
12
91
1.32
0.33
2.3
1.6
—
—
—
0
0
12
91
1.32
0.33
2.3
1.6
—
—
—
0
0
12
91
1.32
0.33
2.3
1.6
—
—
—
0
0
12
91
1.32
0.33
2.3
1.6
—
—
—
0
0
19
155
1.23
0.32
1.4
1.5
144.9
133.8
%
0.22
19
144
31
267
1.16
0.31
1.5
1.6
—
—
—
0
0
2609
25919
1.03
0.31
4.3
4.1
—
—
—
0
0
7
96
0.73
0.30
1.1
1.1
99.9
91.4
%
—
7
96
7
54
1.30
0.30
1.3
1.3
—
—
—
0
0
25
214
1.17
0.27
1.1
1.7
—
—
—
0
0
19
159
1.20
0.26
1.4
1.2
—
—
—
0
0
8
67
1.19
0.26
1.0
1.1
—
—
—
0
0
43
386
1.12
0.26
1.3
1.7
—
—
—
0
0
15
123
1.22
0.25
2.5
3.3
489.3
166.6
umol/l
—
6
68
12
147
0.82
0.23
1.3
1.8
—
2004802.0
—
0
15
89
835
1.07
0.22
1.3
1.3
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
86
915
0.94
0.21
1.0
1.1
0.8
1.7
u/ml
1.46
20
228
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
378
3681
1.03
0.21
1.4
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
52
562
0.92
0.19
1.2
1.2
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
11
132
0.83
0.18
1.2
1.6
3.7
3.6
u/field
—
6
94
16
138
1.16
0.17
1.8
1.9
3.7
3.9
mmol/l
1.27
16
138
16
138
1.16
0.17
1.8
1.9
105.4
106.1
mmol/l
0.19
16
138
16
138
1.16
0.17
1.6
2.3
21.0
215.7
ug/l
0.72
16
130
27
244
1.11
0.16
1.4
1.9
—
—
—
0
0
13
111
1.17
0.15
1.5
1.7
2.3
2.5
mg/l
0.25
13
106
147
1521
0.96
0.14
2.3
2.2
—
—
—
0
0
61
576
1.06
0.14
1.2
1.2
—
—
—
0
0
9
83
1.08
0.14
1.1
1.1
—
—
—
0
0
91
950
0.96
0.14
1.9
1.6
7.5
7.5
mmol/l
0.07
50
586
16
141
1.14
0.14
1.4
1.7
42.3
43.5
%
0.04
11
84
8
96
0.83
0.13
1.1
1.1
—
—
—
0
0
8
98
0.82
0.13
2.8
2.6
—
—
—
0
0
317
3109
1.02
0.12
1.5
1.6
—
—
—
0
0
93
894
1.04
0.12
1.4
1.5
—
—
—
0
0
100
967
1.04
0.10
1.3
1.2
—
—
—
0
0
77
741
1.04
0.10
2.0
1.8
—
—
—
0
0
5
44
1.14
0.10
1.2
1.2
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
9.9
23.9
u/ml
—
5
35
160
1638
0.98
0.09
1.1
1.2
—
—
—
0
0
5
46
1.09
0.09
1.4
3.2
—
—
—
0
0
5
46
1.09
0.09
1.4
3.2
—
—
—
0
0
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
5
48
1.04
0.09
2.0
1.2
—
—
—
0
0
15
136
1.10
0.08
1.0
1.1
—
—
—
0
0
230
2263
1.02
0.08
1.4
1.3
229.1
240.9
miu/ml
0.21
115
1183
14
127
1.10
0.08
1.2
1.1
—
—
—
0
0
8
76
1.05
0.07
1.3
1.3
—
—
—
0
0
8
78
1.03
0.07
1.3
1.3
—
—
—
0
0
9
84
1.07
0.07
2.3
5.7
—
59.1
—
0
13
33
346
0.95
0.06
1.3
2.4
—
—
—
0
0
104
1063
0.98
0.06
1.2
1.1
1.5
1.3
u/ml
0.12
46
420
27
283
0.95
0.05
2.0
2.0
—
—
—
0
0
17
159
1.07
0.05
1.0
1.0
—
—
—
0
0
33
317
1.04
0.05
1.2
1.4
—
—
—
0
0
55
539
1.02
0.03
1.1
1.1
—
—
—
0
0
12
128
0.94
0.02
1.3
1.1
—
—
—
0
0
12
128
0.94
0.02
1.2
1.2
—
—
—
0
0
235
2339
1.01
0.01
1.4
1.4
—
—
—
0
0
80
794
1.01
0.00
1.1
1.1
2.5
5.3
u/ml
0.92
31
309
11
106
1.04
0.00
1.3
1.4
—
—
—
0
0
12
118
1.02
0.00
1.1
1.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
14
137
1.02
0.00
1.0
1.1
—
—
—
0
0
15
153
0.98
0.00
1.3
1.9
1.2
2.4
u/field
—
6
80
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
3.0
—
0
5
8
83
0.96
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
5.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
32.8
—
0
6
6
68
0.88
0.00
1.8
1.5
9.9
7.7
ug/l
—
6
68
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.3
1.6
—
—
—
0
0
8
85
0.94
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
9.2
—
0
6
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
19.9
—
0
6
6
59
1.02
0.00
1.3
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
5.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_OVARDYS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_OVARDYS | 1.99 [1.65, 2.4] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.284 |
During the follow-up period (1.1.1998 — 31.12.2019), 243 out of 12980 females with E4_OVARDYS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have E4_OVARDYS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.18% | No data |
| 5 | 1.088% | No data |
| 10 | 2.691% | No data |
| 15 | 5.534% | No data |
| 20 | 10.04% | No data |
Relationships between endpoints
↥Index endpoint: E4_OVARDYS – Ovarian dysfunction
GWS hits: 7
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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