Ovarian dysfunction, other/unspecified

E4_OVARDYSNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E28.8, E28.9
  • Hospital discharge: ICD-9 256[8-9]
  • Hospital discharge: ICD-8 2569
  • Hospital discharge: excluded ICD-8 25690
  • Cause of death: ICD-10 E28.8, E28.9
  • Cause of death: ICD-9 256[8-9]
  • Cause of death: ICD-8 2569
  • Cause of death: excluded ICD-8 25690

2 out of 7 registries used, show all original rules.

220

4. Check minimum number of events

None

220

5. Include endpoints

None

220

6. Filter based on genotype QC (FinnGen only)

212

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1225 1225 -
Only index persons 1157 1157 -
Unadjusted period prevalence (%)
Whole population 0.04 0.04 -
Only index persons 0.04 0.04 -
Median age at first event (years)
Whole population - 32.36 -
Only index persons - 31.95 -

-FinnGen-

Key figures

All Female Male
Number of individuals 212 212 -
Unadjusted period prevalence (%) 0.08 0.08 -
Median age at first event (years) 33.86 33.86 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
220
Matched controls
2200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E28.8
ICD-10 Finland
Other ovarian dysfunction
+∞
120.1
104
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
57.2
111.0
65
16
E28.9
ICD-10 Finland
Ovarian dysfunction, unspecified
+∞
60.2
55
*
E28.3
ICD-10 Finland
Primary ovarian failure
466.4
40.5
39
*
G03FB08
ATC
dydrogesterone and estrogen; systemic
9.1
37.8
53
74
25691, ,
ICD-8 Finland
+∞
23.3
22
*
25699
ICD-8 Finland
Ovarian dysfunction, Other and unspecified
+∞
20.1
19
*
25698
ICD-8 Finland
Ovarian dysfunction, Alia definita
+∞
19.0
18
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.4
16.8
147
815
N91.1
ICD-10 Finland
Secondary amenorrhoea
13.2
15.6
27
23
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
3.1
14.8
131
713
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
28.6
12.2
16
6
H02AB09
ATC
hydrocortisone; systemic
15.2
10.7
17
12
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
20.0
10.4
15
8
N97.8
ICD-10 Finland
Female infertility of other origin
8.2
9.7
21
28
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
9.2
84
439
G03DB01
ATC
dydrogesterone; oral
2.7
8.5
56
249
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.5
8.4
21
50
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
8.4
8
*
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
18.0
8.2
12
7
N97.9
ICD-10 Finland
Female infertility, unspecified
3.4
7.7
30
99
H01CA02
ATC
nafarelin; nasal
4.5
7.6
19
45
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
7.5
36
134
E89.4
ICD-10 Finland
Postprocedural ovarian failure
82.8
7.5
8
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
7.8
7.3
16
22
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
7.3
7
*
G03GA02
ATC
human menopausal gonadotrophin; parenteral
4.5
7.2
18
43
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
6.8
50
232
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
41.4
6.8
8
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
6.6
28
97
H02AA02
ATC
fludrocortisone; oral
71.8
6.5
7
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
6.9
6.5
15
23
A02BC05
ATC
esomeprazole; systemic
2.1
6.4
96
597
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
6.3
22
67
G03DA02
ATC
medroxyprogesterone; systemic
2.9
6.3
32
123
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
6.3
6
*
H01AC01
ATC
somatropin; parenteral
+∞
6.3
6
*
2568X
ICD-9 Finland
Ovarian dysfunction, Other ovarian dysfunction
+∞
6.3
6
*
G03FA14
ATC
dydrogesterone and estrogen; systemic
3.2
6.2
25
84
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.8
6.1
32
125
SPAT1255
SPAT
Intravenous administration of medicine
3.9
6.1
18
49

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
57
11.35
43.39
1.4
1.1
21.39
9.28
u/l
4.10
40
47
39
48
9.66
30.48
1.5
1.4
0.26
0.52
nmol/l
1.27
27
40
43
60
8.66
30.42
1.6
1.1
2.07
2.65
ug/l
0.39
26
53
55
152
4.49
18.73
2.0
1.2
35.51
23.34
iu/l
1.41
48
130
16
7
24.49
11.75
1.0
1.0
—
—
—
0
0
62
303
2.46
7.66
3.8
2.7
511.45
530.99
mosm/kgh2o
0.31
55
257
20
50
4.30
7.53
1.9
1.4
30.12
21.93
u/l
0.54
20
39
83
468
2.24
7.33
5.8
3.1
7.39
7.40
ph
0.50
19
81
40
166
2.72
6.85
1.4
1.4
—
—
—
0
0
77
433
2.20
6.76
3.6
2.9
0.25
0.40
e6/l
0.61
58
317
76
439
2.12
6.14
3.2
2.8
—
—
—
0
0
40
179
2.51
5.86
2.2
1.5
—
—
—
0
0
96
614
2.00
5.82
4.4
3.4
24.23
54.88
e6/l
1.61
63
390
120
834
1.97
5.67
11.9
7.6
0.00
0.00
e9/l
0.72
100
680
55
288
2.21
5.64
1.6
1.4
524.44
518.18
titre
—
9
66
79
476
2.03
5.62
3.7
2.9
22.06
68.15
e6/l
1.57
60
350
94
603
1.98
5.60
6.9
7.6
1.01
1.10
inr
2.45
25
198
21
69
3.26
5.38
4.0
5.0
24.49
25.10
mmol/l
0.24
21
69
97
638
1.93
5.30
5.9
3.8
36.51
36.85
g/l
0.25
89
601
117
819
1.92
5.29
8.7
4.9
0.71
0.67
%
0.32
110
759
168
1331
2.11
5.27
10.6
6.2
75.37
71.23
u/l
0.64
163
1241
120
856
1.88
5.04
8.6
4.9
2.80
2.69
%
0.19
113
800
41
199
2.30
5.00
2.5
1.9
—
—
—
0
0
121
871
1.86
4.88
9.9
5.3
—
—
—
0
0
188
1577
2.32
4.78
5.6
4.3
14.41
14.33
pmol/l
0.17
176
1456
140
1061
1.88
4.74
13.8
8.1
3.92
3.89
e9/l
0.05
122
929
95
638
1.86
4.74
1.8
1.8
82.45
97.36
pmol/l
2.27
42
321
125
915
1.85
4.73
8.8
4.9
0.04
0.04
e9/l
0.30
112
803
59
339
2.01
4.68
7.8
3.4
—
—
—
0
0
23
87
2.84
4.66
3.8
3.1
62.41
73.33
e9/l
0.56
16
63
119
861
1.83
4.64
9.0
5.2
8.12
7.84
%
0.50
112
807
83
537
1.88
4.64
4.2
2.9
2.36
2.35
mmol/l
0.09
72
480
98
670
1.83
4.58
6.4
4.4
1.21
1.22
mmol/l
0.46
93
613
128
960
1.80
4.32
9.3
5.3
0.17
0.17
e9/l
0.05
119
851
123
914
1.78
4.26
8.9
4.9
0.49
0.52
e9/l
0.83
110
803
9
13
7.16
4.20
1.3
1.2
—
—
nmol/l
—
0
0
104
741
1.77
4.12
7.1
4.9
1.21
1.22
mmol/l
0.58
86
630
49
275
2.01
4.12
1.6
1.4
—
—
—
0
0
13
31
4.39
4.08
4.0
2.7
3.62
4.84
e9/l
1.03
13
31
13
31
4.39
4.08
4.1
3.3
55.69
59.29
%
0.43
13
31
126
952
1.76
4.04
8.9
4.8
1.82
2.08
e9/l
1.17
117
860
110
802
1.74
3.98
2.2
1.9
—
—
—
0
0
119
890
1.73
3.91
8.3
4.8
56.97
56.46
%
0.15
112
837
124
941
1.73
3.84
4.9
3.7
6.38
6.24
mmol/l
0.36
116
829
44
244
2.00
3.81
3.0
2.7
4.77
4.58
e6/l
0.03
16
116
124
943
1.72
3.79
4.3
3.4
0.00
0.02
estimate
0.50
26
179
123
934
1.72
3.78
4.2
3.3
0.00
0.00
estimate
-0.00
27
191
123
934
1.72
3.78
6.4
4.6
0.00
0.01
estimate
0.50
26
184
119
897
1.71
3.74
8.8
4.9
28.99
29.65
%
0.25
112
845
66
421
1.81
3.74
3.4
3.4
—
—
—
0
0
46
263
1.95
3.65
3.3
2.9
100.82
188.07
ng/l
0.38
28
153
104
760
1.70
3.64
4.0
3.0
6.42
5.86
ph
—
6
67
70
460
1.77
3.57
9.5
6.9
—
—
—
0
0
9
17
5.47
3.55
1.3
1.2
—
—
—
0
0
75
506
1.73
3.48
2.3
2.9
11.17
19.43
ng/l
2.45
31
263
36
192
2.05
3.46
3.6
2.2
4.63
5.34
umol/l
0.33
30
161
9
18
5.16
3.41
1.3
1.2
—
—
—
0
0
13
38
3.57
3.37
2.0
1.2
—
—
—
0
0
20
87
2.43
3.11
4.4
7.5
—
—
—
0
0
23
107
2.28
3.09
4.4
3.5
1.23
1.23
mmol/l
0.01
23
91
24
115
2.22
3.02
3.4
4.7
1.07
0.67
%
—
7
33
27
136
2.12
3.01
3.3
2.8
1.93
1.79
%
0.23
27
117
37
210
1.92
2.98
1.4
1.3
133.22
190.03
iu/ml
0.38
11
93
23
109
2.24
2.97
3.0
4.5
1.40
0.61
%
—
5
28
23
109
2.24
2.97
3.3
4.9
0.17
0.11
%
—
6
27
30
162
1.99
2.79
3.9
3.6
—
—
—
0
0
14
54
2.70
2.76
1.6
2.6
1.78
1.36
g/l
0.55
14
48
134
1093
1.58
2.72
3.6
3.0
—
—
—
0
0
9
24
3.86
2.70
2.4
2.5
4.96
4.96
kpa
—
9
24
9
24
3.86
2.70
2.3
2.5
9.68
9.21
kpa
—
9
24
51
332
1.70
2.62
2.4
3.0
1488.78
506.42
mg/l
0.29
30
202
12
44
2.83
2.59
1.8
2.3
—
—
—
0
0
5
7
7.27
2.56
1.0
1.3
2.08
2.47
mg/l
—
5
7
7
16
4.48
2.49
1.4
1.5
92.19
91.15
%
—
7
16
44
279
1.72
2.48
3.1
2.4
2.46
2.42
mmol/l
0.84
34
240
185
1654
1.74
2.38
3.7
3.3
1.36
1.16
mmol/l
2.22
179
1542
193
1747
1.85
2.37
4.0
3.6
4.79
4.79
mmol/l
0.02
186
1645
192
1736
1.83
2.36
3.9
3.6
1.57
1.57
mmol/l
0.04
185
1629
53
358
1.63
2.36
3.3
3.5
4.23
11.61
mg/mmol
0.91
27
204
34
203
1.80
2.35
3.0
1.8
28.99
29.10
s
0.05
34
198
61
428
1.59
2.33
3.0
2.0
2.64
2.68
mg/l
0.06
53
362
13
53
2.54
2.32
1.5
3.0
24.85
24.62
mmol/l
0.14
13
53
26
143
1.93
2.31
1.8
1.3
237.22
281.14
u/ml
0.08
26
131
78
581
1.53
2.28
3.6
1.9
—
—
—
0
0
7
18
3.98
2.27
1.6
1.0
—
—
—
0
0
11
41
2.77
2.24
1.3
1.4
—
—
—
0
0
194
1766
1.83
2.24
4.5
4.0
2.86
2.85
mmol/l
0.06
186
1652
204
1888
2.11
2.23
19.7
10.5
23.60
18.94
mg/l
1.01
166
1415
5
9
5.65
2.22
2.2
2.0
0.17
0.24
e9/l
—
5
9
23
123
1.97
2.21
1.3
1.1
—
—
—
0
0
158
1369
1.55
2.21
5.6
3.7
11.82
9.50
mm/h
1.50
149
1251
197
1808
1.86
2.12
6.5
5.0
1.63
1.74
mu/l
0.90
189
1696
55
386
1.57
2.08
1.4
1.3
19.88
9.39
u/ml
0.28
13
149
5
10
5.09
2.08
3.0
1.8
35.34
43.68
%
—
5
10
55
388
1.56
2.03
1.4
1.3
26.15
16.25
iu/ml
0.54
13
117
10
38
2.71
2.03
4.3
4.0
0.93
1.18
mg/l
—
10
32
153
1331
1.49
1.97
5.9
4.0
—
—
—
0
0
5
11
4.62
1.95
1.2
1.6
—
—
—
0
0
6
16
3.82
1.95
2.5
2.7
—
—
—
0
0
210
1984
2.29
1.83
14.5
9.6
—
—
—
0
0
187
1709
1.63
1.82
4.2
3.6
5.65
5.63
mmol/l
0.11
176
1581
7
23
3.11
1.81
1.3
1.1
—
—
—
0
0
7
23
3.11
1.81
1.3
1.2
10.07
35.17
nmol/l
—
7
18
7
23
3.11
1.81
1.4
2.0
—
—
—
0
0
20
110
1.90
1.80
1.9
2.8
—
—
—
0
0
27
164
1.74
1.78
1.4
1.4
—
—
—
0
0
58
426
1.49
1.77
2.5
1.8
1.18
0.84
mg/l
0.31
43
309
6
18
3.40
1.76
2.0
1.3
—
—
—
0
0
30
189
1.68
1.74
2.6
2.2
1957.49
3707.24
u/l
0.37
14
82
7
25
2.86
1.66
1.1
1.4
—
—
—
0
0
5
15
3.38
1.53
1.2
1.4
—
—
—
0
0
35
238
1.56
1.52
1.3
1.2
—
—
—
0
0
62
476
1.42
1.49
3.8
3.7
0.00
0.01
estimate
0.80
26
185
5
16
3.17
1.44
1.6
1.3
—
—
—
0
0
6
22
2.77
1.44
1.2
1.1
—
—
—
0
0
23
144
1.67
1.39
3.0
4.2
22.75
9.01
ug/l
0.28
13
113
23
146
1.64
1.32
1.5
1.3
—
—
—
0
0
54
414
1.40
1.30
2.4
2.7
7.63
7.69
mmol/l
0.03
43
352
6
25
2.44
1.25
2.7
1.6
—
—
—
0
0
15
86
1.80
1.22
1.3
1.3
—
—
—
0
0
5
19
2.67
1.22
1.6
6.5
—
—
—
0
0
5
19
2.67
1.22
1.0
2.0
—
—
—
0
0
12
64
1.93
1.20
5.9
8.3
95.91
94.56
%
0.66
12
64
7
140
0.48
1.13
4.4
3.4
—
—
—
0
0
7
31
2.30
1.11
2.3
3.1
—
—
—
0
0
7
35
2.03
1.01
1.0
1.3
—
—
—
0
0
34
252
1.41
1.00
2.3
1.6
1373.32
1091.29
nmol/l
0.93
28
185
51
405
1.34
0.99
3.3
3.3
1.02
1.02
kg/l
—
7
62
12
69
1.78
0.98
1.8
2.2
—
—
—
0
0
5
23
2.20
0.98
1.4
1.0
—
—
—
0
0
5
23
2.20
0.98
1.2
1.0
—
—
—
0
0
10
54
1.89
0.98
3.1
8.4
—
—
—
0
0
116
1030
1.27
0.96
3.5
2.8
74.61
64.97
ug/l
0.23
108
961
80
679
1.28
0.96
1.7
1.7
—
—
—
0
0
0
32
0.00
0.96
0.0
1.6
—
—
—
0
0
18
118
1.57
0.94
2.8
3.4
—
—
—
0
0
14
86
1.67
0.93
6.9
2.8
—
—
—
0
0
165
1534
1.30
0.92
5.2
4.2
39.51
37.60
mmol/mol
1.40
154
1437
68
569
1.28
0.91
2.4
2.6
—
—
—
0
0
16
103
1.60
0.90
1.4
1.4
—
—
—
0
0
8
137
0.57
0.86
1.4
1.4
—
—
—
0
0
8
46
1.77
0.83
1.3
2.3
—
—
—
0
0
13
81
1.64
0.83
1.5
1.7
—
—
—
0
0
10
58
1.76
0.81
1.3
1.1
—
—
—
0
0
65
552
1.25
0.76
4.5
2.8
—
—
—
0
0
8
136
0.57
0.75
1.4
1.4
—
—
—
0
0
32
248
1.34
0.74
1.2
1.2
—
—
—
0
0
6
109
0.54
0.74
1.0
1.4
—
—
—
0
0
7
38
1.87
0.74
5.6
3.7
—
—
—
0
0
9
142
0.62
0.72
1.3
1.5
—
—
—
0
0
7
40
1.77
0.72
2.1
1.3
—
—
—
0
0
5
27
1.87
0.69
1.2
1.2
—
—
—
0
0
61
521
1.24
0.68
1.8
1.7
—
—
—
0
0
12
78
1.57
0.67
1.5
1.9
2.83
4.00
ug/l
0.49
12
67
5
28
1.80
0.66
1.0
1.1
—
—
—
0
0
35
281
1.29
0.65
1.8
2.0
—
—
—
0
0
18
130
1.42
0.63
1.1
1.1
—
—
—
0
0
49
413
1.24
0.62
2.9
3.1
—
—
—
0
0
11
72
1.56
0.60
1.1
1.2
—
—
—
0
0
8
52
1.56
0.60
2.4
2.1
0.88
0.63
%
—
8
52
6
35
1.73
0.58
2.7
2.4
38.67
39.11
g/l
—
6
35
8
54
1.50
0.58
2.4
2.1
0.86
1.15
%
—
8
54
54
464
1.22
0.57
1.6
1.6
1.74
1.29
mmol/l
0.93
45
405
5
89
0.55
0.57
1.2
1.8
—
—
—
0
0
8
122
0.64
0.56
1.0
1.4
—
—
—
0
0
8
121
0.65
0.56
1.0
1.4
—
—
—
0
0
8
121
0.65
0.56
1.0
1.4
—
—
—
0
0
8
121
0.65
0.56
1.0
1.4
—
—
—
0
0
6
37
1.64
0.56
2.7
3.0
—
—
—
0
0
136
1272
1.18
0.55
2.8
2.7
34.86
31.95
u/l
0.31
131
1210
175
1674
1.22
0.54
24.8
13.4
330.67
331.59
g/l
0.70
175
1666
9
61
1.50
0.54
1.4
1.9
—
—
—
0
0
6
98
0.60
0.53
1.0
1.4
—
—
—
0
0
26
316
0.80
0.45
1.3
1.4
—
—
—
0
0
40
464
0.83
0.45
1.7
1.7
—
—
—
0
0
5
31
1.63
0.43
1.2
1.1
—
—
—
0
0
25
205
1.25
0.41
1.6
1.2
—
—
—
0
0
8
59
1.37
0.41
2.3
3.7
—
—
—
0
0
5
34
1.48
0.40
2.4
5.8
1.36
1.07
mmol/l
—
5
28
24
197
1.25
0.40
2.2
1.3
—
—
—
0
0
5
36
1.40
0.38
1.8
1.1
44.20
258.58
ug/l
—
5
30
69
628
1.14
0.37
2.2
2.0
—
—
—
0
0
6
45
1.34
0.34
2.3
1.2
4.38
3.66
mmol/l
—
6
38
59
539
1.13
0.30
1.4
1.3
0.53
1.43
u/ml
1.71
18
130
35
308
1.16
0.30
1.9
2.1
192.25
68.48
ug/g
0.97
26
233
8
65
1.24
0.27
1.3
1.2
—
—
—
0
0
14
114
1.24
0.25
1.4
1.3
250.72
273.35
miu/ml
—
7
54
12
147
0.81
0.24
1.4
1.4
—
—
—
0
0
12
146
0.81
0.23
1.2
1.2
—
—
—
0
0
5
42
1.19
0.21
1.2
1.0
—
—
—
0
0
5
42
1.19
0.21
1.2
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
52
482
1.10
0.21
1.5
1.3
1.69
2.01
g/l
2.18
30
288
21
239
0.87
0.20
1.1
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
127.99
—
0
14
6
49
1.23
0.20
4.7
7.0
—
—
—
0
0
6
51
1.18
0.19
3.8
3.1
27.83
34.30
u/ml
—
6
51
6
53
1.14
0.19
2.2
2.0
—
—
—
0
0
17
147
1.17
0.18
1.4
1.3
—
50.79
—
0
8
6
80
0.74
0.15
1.8
2.2
—
—
—
0
0
65
680
0.94
0.13
2.7
2.4
—
—
—
0
0
11
125
0.87
0.10
2.4
2.5
—
—
—
0
0
21
195
1.09
0.08
1.2
1.1
—
—
—
0
0
18
166
1.09
0.08
2.9
2.2
—
19.05
—
0
10
8
74
1.08
0.07
1.6
1.2
—
—
—
0
0
7
85
0.82
0.07
1.7
1.8
—
—
—
0
0
17
177
0.96
0.01
1.2
1.6
—
—
—
0
0
14
139
1.01
0.00
1.7
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
1.56
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
0.82
—
0
9
9
95
0.95
-0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
462.63
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
12.07
—
0
7
0
5
0.00
-0.00
0.0
11.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.01
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
15.70
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
1792.13
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_OVARDYSNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_OVARDYSNAS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_OVARDYSNAS – Ovarian dysfunction, other/unspecified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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