ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2914 |
4. Check minimum number of eventsNone |
2914 |
5. Include endpointsNone |
2914 |
6. Filter based on genotype QC (FinnGen only) |
2914 |
Control definitions (FinnGen only)
- Control exclude
- K11_ENERCOLNONINF
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K50
- Name in latin
- Alis morbus Crohn specificatus
Similar endpoints
↥List of similar endpoints to
Other Crohn's disease
based on the number of shared cases.
Similar with more cases:
- Crohn disease
- Inflammatory bowel disease
- Noninfective enteritis and colitis
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14492 | 7232 | 7199 |
| Only index persons | 13958 | 7026 | 6932 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.21 | 0.20 |
| Only index persons | 0.26 | 0.26 | 0.26 |
| Median age at first event (years) | |||
| Whole population | 38.98 | 39.26 | 38.69 |
| Only index persons | 38.52 | 38.89 | 38.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2914 | 1623 | 1291 |
| Unadjusted period prevalence (%) | 0.56 | 0.55 | 0.57 |
| Median age at first event (years) | 40.91 | 39.86 | 42.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2649
- Matched controls
- 26489
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
323.0
587
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
323.0
2649
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
323.0
2333
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
13151.3
323.0
1362
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
726.5
323.0
701
13
K50.9
ICD-10 Finland
Crohn disease, unspecified
13881.6
323.0
1399
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
7.8
323.0
1498
3771
K51.5
ICD-10 Finland
Left sided colitis
7210.0
323.0
580
*
K50
ICD-10 Finland
Crohn disease [regional enteritis]
1875.1
323.0
320
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
16384.0
323.0
1238
*
UJF32
NOMESCO Finland
Coloscopy
34.6
323.0
2117
2730
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
59.3
323.0
416
83
K51.8
ICD-10 Finland
Other ulcerative colitis
4492.8
323.0
396
*
H02AB06
ATC
prednisolone; systemic
7.6
323.0
1998
7628
L04AB04
ATC
adalimumab; parenteral
39.3
323.0
503
157
P01AB01
ATC
metronidazole; oral, rectal
5.0
323.0
1660
6640
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
203.5
323.0
413
24
A07EC02
ATC
mesalazine; oral, rectal
798.6
323.0
1926
88
L04AX01
ATC
azathioprine; systemic
199.5
323.0
1672
226
A07EA06
ATC
budesonide; oral, local oral
569.3
323.0
1374
50
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.3
323.0
1336
3672
UJF92
NOMESCO Finland
Capsular endoscopy
54.0
323.0
515
118
A07EA02
ATC
hydrocortisone; rectal
175.0
323.0
451
31
UJF30
NOMESCO Finland
Ileoscopy through colon
32.4
323.0
1308
773
L01BB02
ATC
mercaptopurine; oral
178.8
323.0
396
26
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
300.9
283
*
ZX120
NOMESCO Finland
Intravenous
8.9
286.8
671
967
A07EC01
ATC
sulfasalazine; oral, rectal
9.2
280.5
644
896
J01MA02
ATC
ciprofloxacin; systemic
4.4
270.9
1475
5878
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
253.3
269.8
273
12
H02AB07
ATC
prednisone; oral
6.6
267.7
794
1611
C10AC01
ATC
colestyramine; oral
26.6
254.2
359
155
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
246.8
233
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
9.3
228.1
513
670
D94
ICPC
Chronic enteritis/ulcerative colitis
288.2
210.4
212
8
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
6.6
209.3
601
1126
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
2007.9
205.8
197
*
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
200.6
190
*
JF1BD
NOMESCO Finland
Very extensive small bowel CT
169.8
195.7
204
13
4AA12
NOMESCO Finland
NA
377.9
178.7
178
5
TPH04
NOMESCO Finland
Cathetrisation of vein
4.0
175.5
867
2864
4AB02
NOMESCO Finland
NA
202.9
166.0
171
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
163.8
1326
6368
WX002
NOMESCO Finland
Sedation and analgesia
4.0
159.7
759
2390
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
64.6
155.7
181
30
L04AC05
ATC
ustekinumab; parenteral
80.0
152.6
172
23
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.0
149.7
1273
6200
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
10.0
147.2
310
347
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.1
145.7
519
1216
JFB20
NOMESCO Finland
Ileocaecal resection
93.9
143.9
159
18
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
15.3
143.3
244
174
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
60.6
140.5
165
29
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
36.1
137.9
179
53
B03BA03
ATC
hydroxocobalamin; parenteral
8.9
135.4
304
379
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
129.2
123
*
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
128.2
122
*
K60.3
ICD-10 Finland
Anal fistula
14.6
123.6
214
158
JFB00
NOMESCO Finland
Partial resection of small intestine
22.0
121.8
181
88
A02BC02
ATC
pantoprazole; systemic
2.7
121.5
1801
11706
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
412.2
119.6
119
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.3
112.8
693
2580
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
36.9
108.6
140
40
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.2
108.0
312
558
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
364.7
106.0
106
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.7
104.3
516
1611
5550A
ICD-9 Finland
Regional enteritis, Small intestine
+∞
103.8
99
*
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
123.8
99.7
107
9
JF1AD
NOMESCO Finland
Small bowel CT
55.5
98.4
117
22
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
14.9
97.6
167
119
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.3
93.9
266
461
JHA00
NOMESCO Finland
Anal or perianal incision
12.4
89.5
166
142
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.1
88.9
381
1038
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
232.7
88.0
90
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
86.9
83
*
UJF02
NOMESCO Finland
Peroral enteroscopy
41.7
86.1
108
27
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
85.9
852
4176
107
Kela drug reimbursment
Pernicious anaemia
15.9
84.9
141
93
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
84.8
81
*
1370
FHL
Colonoscopy, whole colon
177.6
82.6
86
5
N02AX02
ATC
tramadol; systemic, rectal
2.3
81.5
1158
6761
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
81.3
678
2994
K61.0
ICD-10 Finland
Anal abscess
10.0
80.7
167
177
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
123.8
78.4
84
7
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
6.2
77.8
222
386
K83.0
ICD-10 Finland
Cholangitis
17.3
77.2
124
75
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
75.2
466
1690
K51
ICD-10 Finland
Ulcerative colitis
377.6
74.1
74
*
B81
ICPC
Anaemia vit B12/folate deficiency
7.9
72.9
173
231
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
716.9
71.4
70
*
K56.7
ICD-10 Finland
Ileus, unspecified
19.1
71.1
110
60
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
69.0
66
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.6
68.9
259
615
A07DA03
ATC
loperamide; oral
6.8
68.6
180
279
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
182.2
68.4
71
*
M45
ICD-10 Finland
Ankylosing spondylitis
8.1
68.1
159
207
4AA33
NOMESCO Finland
NA
+∞
64.8
62
*
A02BC03
ATC
lansoprazole; oral
2.3
64.5
772
4045
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.1
63.5
382
1345
Z93.2
ICD-10 Finland
Ileostomy status
81.1
63.3
71
9
N02BE01
ATC
paracetamol; systemic, rectal
2.3
62.2
2232
18416
3042
Kela drug reimbursment
NA
+∞
60.6
58
*
253
Kela drug reimbursment
NA
+∞
59.6
57
*
A07EA01
ATC
prednisolone; rectal
158.6
59.1
62
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
12.8
59.0
107
87
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
10.8
58.9
116
112
A05AA02
ATC
ursodeoxycholic acid; oral
8.7
57.2
127
152
JN3AD
NOMESCO Finland
Abdominal CT examination
3.7
55.9
266
780
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
39.9
55.6
70
18
3AC01
NOMESCO Finland
NA
13.8
54.9
96
72
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
538.5
53.7
53
*
A02BC01
ATC
omeprazole; systemic
2.2
53.6
709
3833
6403
FHL
Ileocal resection
276.4
53.3
54
*
WVA20
NOMESCO Finland
Medicine administration
7.6
53.2
129
178
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
53.1
620
3163
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
74.2
51.2
58
8
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
51.2
49
*
R50.9
ICD-10 Finland
Fever, unspecified
2.6
51.1
437
1900
J01MA12
ATC
levofloxacin; systemic
2.4
50.3
479
2202
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
+∞
50.1
48
*
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
50.1
48
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
49.1
47
*
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
244.2
47.1
48
*
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
47.0
45
*
WX402
NOMESCO Finland
General anaesthesia
2.3
46.6
523
2600
JAH00
NOMESCO Finland
Laparotomy
6.4
44.9
122
198
JFB30
NOMESCO Finland
Right hemicolectomy
13.6
44.5
78
59
H02AB09
ATC
hydrocortisone; systemic
6.4
44.3
121
198
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.1
42.5
120
205
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
42.0
195
557
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
41.7
1001
6647
JHD20
NOMESCO Finland
Incision of fistula-in-ano
10.8
41.1
80
76
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.5
41.0
110
176
UJH02
NOMESCO Finland
Anoscopy
4.2
40.4
159
392
J01DB01
ATC
cefalexin; oral
1.9
40.1
2158
18409
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
32.5
38.9
51
16
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.2
38.8
155
388
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
38.6
281
1102
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.4
38.5
145
343
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
25.0
38.5
54
22
D64.9
ICD-10 Finland
Anaemia, unspecified
3.1
38.2
230
799
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
197.8
37.9
39
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.0
37.6
107
185
WW200
NOMESCO Finland
Immunization
4.7
37.5
132
291
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
9.5
37.5
78
84
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.2
37.2
92
131
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
37.1
571
3214
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
23.5
37.1
53
23
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
36.9
248
924
K92.1
ICD-10 Finland
Melaena
4.3
36.6
143
350
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
36.5
35
*
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
6.0
36.5
103
176
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.3
36.1
194
621
L04AD01
ATC
ciclosporin; systemic
6.2
36.0
99
164
B01AB05
ATC
enoxaparin; parenteral
1.9
36.0
677
4097
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
36.0
254
976
L04AA33
ATC
vedolizumab; parenteral
+∞
35.5
34
*
JFF13
NOMESCO Finland
Terminal enterostomy
67.5
35.0
40
6
UJD02
NOMESCO Finland
Gastroscopy
3.8
34.9
156
431
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
79.2
34.9
39
5
A07EC03
ATC
olsalazine; oral
182.3
34.8
36
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
182.3
34.8
36
*
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
18.0
34.0
53
30
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.3
34.0
106
205
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
341.3
34.0
34
*
A02BA02
ATC
ranitidine; systemic
2.1
33.9
439
2295
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
33.8
471
2537
6402
FHL
Small bowel resection
93.8
33.8
37
*
M05BA04
ATC
alendronic acid; oral
3.4
33.5
173
538
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.5
33.3
283
1209
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
22.2
33.1
48
22
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.0
32.3
202
719
C05AA08
ATC
fluocortolone; rectal, topical
2.2
32.2
365
1798
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
31.7
1147
8398
H02AB04
ATC
methylprednisolone; systemic
2.2
31.5
371
1855
K61.1
ICD-10 Finland
Rectal abscess
27.3
31.5
43
16
A07AA09
ATC
vancomycin; oral
10.4
31.4
62
61
JFF10
NOMESCO Finland
Loop enterostomy
21.2
31.3
46
22
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.2
30.9
171
560
4AC05
NOMESCO Finland
NA
+∞
30.3
29
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
11.0
30.2
58
54
K56.0
ICD-10 Finland
Paralytic ileus
12.2
29.7
54
45
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.4
29.6
151
465
K59.1
ICD-10 Finland
Functional diarrhoea
3.7
29.5
135
381
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
8.1
29.1
66
83
ZX112
NOMESCO Finland
Subcutaneous
5.5
29.0
88
165
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
14.8
28.7
48
33
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
28.7
1075
7879
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
9.6
28.6
59
63
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.4
28.6
145
445
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
284.3
27.8
28
*
UJK12
NOMESCO Finland
Peroral cholangioscopy
33.1
27.8
36
11
Z93
ICD-10 Finland
Artificial opening status
25.7
27.5
38
15
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
47.7
27.4
33
7
UJK02
NOMESCO Finland
ERCP
5.9
27.4
78
136
6455
FHL
Perianal fistula surgery
20.3
26.9
40
20
A03CA02
ATC
clidinium and psycholeptics; oral
3.3
26.9
143
455
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
26.7
186
708
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.5
26.1
95
218
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.2
25.9
71
118
A02BC05
ATC
esomeprazole; systemic
1.6
25.8
927
6667
D01
ICPC
Abdominal pain/cramps general
2.1
25.5
299
1484
E0000UV
ATC
NA
1.6
25.5
980
7167
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
24.9
200
826
TJF80
NOMESCO Finland
Ostomy education
10.2
24.7
49
49
6404
FHL
Hemicolectomy on the right
90.9
24.7
27
*
J05AB11
ATC
valaciclovir; oral
2.0
24.6
340
1809
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
24.6
275
1340
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
7.3
24.5
59
82
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
24.4
567
3603
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
24.3
230
1035
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
24.2
315
1635
K63.2
ICD-10 Finland
Fistula of intestine
56.5
24.0
28
5
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
12.1
23.7
43
36
L04AB06
ATC
golimumab; parenteral
9.4
23.7
49
53
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.7
23.4
106
298
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
47.1
23.3
28
6
D07AC01
ATC
betamethasone; topical
1.6
23.2
780
5483
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
23.0
388
2220
JF1CD
NOMESCO Finland
Extensive small bowel CT
+∞
22.9
22
*
K29.8
ICD-10 Finland
Duodenitis
11.2
22.9
43
39
K65.0
ICD-10 Finland
Acute peritonitis
6.8
22.6
57
85
K29.7
ICD-10 Finland
Gastritis, unspecified
3.7
22.6
100
276
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
5.7
22.5
65
116
R11
ICD-10 Finland
Nausea and vomiting
2.4
22.4
207
919
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
45.4
22.4
27
6
J02AC01
ATC
fluconazole; systemic
1.5
21.9
973
7287
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
21.9
21
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
21.9
21
*
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
9.0
21.8
46
52
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
21.8
810
5819
JFB96
NOMESCO Finland
Other partial excision of intestine
80.8
21.7
24
*
K60.4
ICD-10 Finland
Rectal fistula
20.2
21.7
32
16
D06BX01
ATC
metronidazole; topical
2.1
21.6
258
1289
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
21.5
753
5330
UJG02
NOMESCO Finland
Proctoscopy
4.7
21.1
72
156
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
21.0
212
982
WX110
NOMESCO Finland
Local anesthesy
1.5
20.9
1779
15268
M81.4
ICD-10 Finland
Drug-induced osteoporosis
19.6
20.8
31
16
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
7.7
20.8
48
63
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
9.7
20.8
42
44
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.5
20.8
98
285
L88
ICD-10 Finland
Pyoderma gangrenosum
37.5
20.8
26
7
A06AC51
ATC
ispaghula, combinations; systemic
2.9
20.7
130
464
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
20.2
215
1021
B04AD01
ATC
NA
32.8
20.2
26
8
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
5.8
20.1
57
100
Z93.3
ICD-10 Finland
Colostomy status
9.4
20.1
41
44
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.3
20.0
103
321
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
5.0
19.9
64
130
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.8
19.9
85
228
B02.9
ICD-10 Finland
Zoster without complication
2.9
19.9
125
447
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.2
19.8
107
346
Z94.4
ICD-10 Finland
Liver transplant status
15.4
19.7
32
21
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.1
19.7
112
374
JFA60
NOMESCO Finland
Stricturoplasty in small intestine
201.4
19.6
20
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
19.5
920
6935
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.8
19.4
83
223
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.9
18.9
79
208
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.0
18.9
52
88
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.5
18.7
90
267
L04AA01
ATC
[U] ciclosporin; systemic
5.1
18.7
59
118
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
14.2
18.6
31
22
RD210
NOMESCO Finland
NA
3.8
18.4
78
208
1490
FHL
Sigmoideoscopy (fiberscope)
15.1
18.4
30
20
JJC00
NOMESCO Finland
Allogenic transplantation of liver
30.2
18.3
24
8
E86
ICD-10 Finland
Volume depletion
4.9
18.3
60
125
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
18.1
648
4575
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
18.0
1191
9575
B01AB10
ATC
tinzaparin; parenteral
2.4
17.9
159
693
S18
ICPC
Laceration/cut
1.5
17.9
871
6584
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
3.0
17.8
105
361
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
17.7
17
*
UKC02
NOMESCO Finland
Cystoscopy
1.9
17.6
287
1615
J05AB01
ATC
aciclovir; systemic
1.6
17.5
473
3107
K60.2
ICD-10 Finland
Anal fissure, unspecified
4.2
17.5
67
164
L01BB01
ATC
NA
21.0
17.3
25
12
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
4.1
17.2
67
166
WW500
NOMESCO Finland
Blood transfusion
3.1
17.2
96
318
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
17.2
156
687
K76.9
ICD-10 Finland
Liver disease, unspecified
5.1
17.1
54
108
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
31.7
17.0
22
7
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
14.1
16.8
28
20
JFA96
NOMESCO Finland
Other local operation on intestine
90.6
16.6
18
*
D07AD01
ATC
clobetasol; topical
1.7
16.5
349
2132
E000001
ATC
NA
1.6
16.5
492
3308
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.2
16.5
88
283
5660A
ICD-9 Finland
Abscess of anal and rectal regions[ABSCESSUS ANI ET ANORECTALIS]
20.2
16.4
24
12
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
4.6
16.4
57
127
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
16.4
284
1633
R4190
NOMESCO Finland
Nutritional therapy
2.8
16.3
105
383
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
16.2
771
5769
D50.8
ICD-10 Finland
Other iron deficiency anaemias
5.1
16.2
51
102
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
16.8
16.1
25
15
5651A
ICD-9 Finland
Anal fissure and fistula, Anal fistula[FISTULA ANI]
18.6
16.0
24
13
JFB46
NOMESCO Finland
Resection of sigmoid colon
8.2
16.0
35
43
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
21.1
16.0
23
11
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
4.0
15.9
63
159
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
15.9
124
505
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
15.9
163
762
A07AA02
ATC
nystatin; oral
2.4
15.9
136
581
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
15.6
15
*
K60.1
ICD-10 Finland
Chronic anal fissure
3.6
15.6
71
203
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
19.3
15.5
23
12
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
160.9
15.5
16
*
4AA17
NOMESCO Finland
NA
160.9
15.5
16
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.6
15.4
114
449
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.4
15.4
137
599
R4110
NOMESCO Finland
Physiotherapy
1.5
15.4
568
4017
6419
FHL
Other measure in this category
38.3
15.4
19
5
S10
ICPC
Boil/carbuncle
2.3
15.3
141
625
L52
ICD-10 Finland
Erythema nodosum
7.3
15.2
36
50
6454
FHL
Incision of perianal abscess
28.8
15.2
20
7
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
10.9
15.0
28
26
R10.0
ICD-10 Finland
Acute abdomen
2.9
15.0
91
319
K85
ICD-10 Finland
Acute pancreatitis
4.6
14.9
51
112
D07AC13
ATC
mometasone; topical
1.5
14.9
649
4755
JAH01
NOMESCO Finland
Laparoscopy
2.4
14.8
127
545
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
14.7
209
1118
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
14.7
436
2925
A01AB09
ATC
miconazole; local oral
2.0
14.7
188
964
C10AC02
ATC
colestipol; oral
13.3
14.7
25
19
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
14.6
14
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
14.6
14
*
UJF34
NOMESCO Finland
Left colonoscopy
7.8
14.6
33
43
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
14.6
385
2505
1380
FHL
Colonoscopy, left side
80.5
14.6
16
*
K02.1
ICD-10 Finland
Caries of dentine
1.4
14.6
1471
12572
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
14.5
398
2614
M13.9
ICD-10 Finland
Arthritis, unspecified
2.1
14.5
163
792
J01FA10
ATC
azithromycin; systemic
1.4
14.5
1475
12618
B07.9
ICD-10 Finland
Verruca simplex
2.6
14.4
105
412
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
14.3
162
791
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
27.3
14.3
19
7
WX610
NOMESCO Finland
Patient controlled analgesia
6.3
14.3
37
59
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.8
14.2
60
161
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.8
14.2
60
162
JFA70
NOMESCO Finland
Suture of small intestine
10.9
14.0
26
24
J01DA01
ATC
[U] cefalexin; systemic
1.4
13.9
1482
12733
K30
ICD-10 Finland
Functional dyspepsia
1.8
13.9
233
1323
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.4
13.9
122
531
L73.8
ICD-10 Finland
Other specified follicular disorders
5.5
13.9
40
73
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
12.7
13.9
24
19
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.6
13.8
35
54
JFB43
NOMESCO Finland
Left hemicolectomy
11.5
13.8
25
22
M01AH01
ATC
celecoxib; oral (coxibs)
1.6
13.7
346
2218
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
13.7
367
2393
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
6.4
13.7
35
55
127
Kela drug reimbursment
Transplant complication
4.0
13.6
54
138
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
13.6
235
1349
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
13.5
13
*
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
13.5
13
*
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
+∞
13.5
13
*
JF2AB
NOMESCO Finland
Colongraphy with X-ray
16.3
13.4
21
13
JFB50
NOMESCO Finland
Other resection of colon
25.9
13.4
18
7
K62.4
ICD-10 Finland
Stenosis of anus and rectum
21.2
13.3
19
9
J01FA06
ATC
roxithromycin; oral
1.4
13.3
881
6966
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
13.3
180
948
L73.2
ICD-10 Finland
Hidradenitis suppurativa
4.7
13.2
44
95
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
13.2
212
1187
D11
ICPC
Diarrhoea
1.7
13.1
285
1752
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.7
13.1
301
1882
D07XC01
ATC
betamethasone, combinations; topical
1.8
13.0
251
1491
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
28.5
12.9
17
6
JHD00
NOMESCO Finland
Anal dilatation
7.4
12.9
30
41
WZC30
NOMESCO Finland
Teaching
1.7
12.9
277
1699
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
12.9
133
625
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
12.8
1673
14764
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
7.5
12.7
29
39
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.0
12.6
172
905
TQW99
NOMESCO Finland
Other minor procedure on skin
2.5
12.6
100
413
6408
FHL
Colectomy and ileostomy
+∞
12.5
12
*
JKA20
NOMESCO Finland
Cholecystectomy
3.7
12.5
53
144
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.9
12.5
73
252
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.1
12.5
47
115
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.2
12.5
120
547
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
24.4
12.5
17
7
JHD96
NOMESCO Finland
Other incision of anal sphincter
24.4
12.5
17
7
J01FF01
ATC
clindamycin; systemic
1.4
12.4
587
4346
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
20.1
12.4
18
9
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
13.2
12.4
21
16
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
4.7
12.4
41
88
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
5.3
12.4
37
71
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
12.3
238
1413
N02AA05
ATC
oxycodone; systemic
1.8
12.3
233
1376
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
12.3
202
1138
M03BX02
ATC
tizanidine; oral
1.3
12.2
1480
12847
S97
ICPC
Chronic ulcer skin
2.5
12.2
92
370
M50.8
ICD-10 Finland
Other cervical disc disorders
7.8
12.1
27
35
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
12.1
288
1817
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.6
12.0
90
360
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
11.8
232
1383
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.5
11.8
53
152
R06AE07
ATC
cetirizine; oral
1.3
11.7
1042
8602
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
9.7
11.7
23
24
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
11.6
1239
10518
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
19.0
11.6
17
9
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
11.6
216
1270
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
11.5
1316
11281
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
11.5
154
807
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.3
11.5
100
435
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
4.0
11.5
44
110
K74.3
ICD-10 Finland
Primary biliary cirrhosis
7.9
11.3
25
32
Y0599
ICD-8 Finland
Investigation of digestive system
4.3
11.3
41
97
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.7
11.3
76
287
A06AD11
ATC
lactulose; oral
1.7
11.3
224
1343
D99
ICPC
Disease digestive system other
5.0
11.2
35
71
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
11.2
211
1244
L04AA06
ATC
mycophenolic acid; systemic
3.4
11.1
53
159
5604
FHL
Vascular preparation or cannulation in the operating room
20.1
11.1
16
8
K63.0
ICD-10 Finland
Abscess of intestine
20.1
11.1
16
8
D95
ICPC
Anal fissure/perianal abscess
5.2
11.0
33
64
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
11.2
11.0
20
18
L88
ICPC
Rheumatoid/seropositive arthritis
2.5
11.0
87
358
WX004
NOMESCO Finland
Patient-controlled sedation
8.6
11.0
23
27
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.9
11.0
68
242
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
10.1
11.0
21
21
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.1
11.0
59
194
M25.5
ICD-10 Finland
Pain in joint
1.4
11.0
626
4792
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
13.9
11.0
18
13
QBA10
NOMESCO Finland
Incision of skin of trunk
4.2
10.9
40
96
JK3MN
NOMESCO Finland
Bile absorbtion isotope examination
43.5
10.9
13
*
M05BB03
ATC
alendronic acid and colecalciferol; oral
3.9
10.8
43
112
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
10.7
238
1475
N20.1
ICD-10 Finland
Calculus of ureter
2.5
10.7
83
342
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
10.6
953
7844
SPAT1263
SPAT
Sampling
1.3
10.6
950
7819
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.6
10.6
47
134
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.0
10.6
23
29
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.2
10.6
53
166
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.6
10.6
46
129
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
10.6
613
4701
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
10.6
297
1959
JAD10
NOMESCO Finland
Repair of incisional hernia
5.7
10.6
29
51
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
4.3
10.5
38
90
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
11.2
10.5
19
17
J01AA02
ATC
doxycycline; systemic
1.3
10.5
1755
15799
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.1
10.4
55
179
S01FA02
ATC
scopolamine; ophthalmic
5.4
10.4
30
56
H15.1
ICD-10 Finland
Episcleritis
3.8
10.4
42
111
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.3
10.3
92
405
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.3
10.3
95
427
K61.2
ICD-10 Finland
Anorectal abscess
10.6
10.3
19
18
H15.0
ICD-10 Finland
Scleritis
10.6
10.3
19
18
M54.5
ICD-10 Finland
Low back pain
1.4
10.2
708
5591
SPAT1153
SPAT
Removal of sutures
1.4
10.2
598
4589
WX892
NOMESCO Finland
Monitored bed care
1.9
10.2
140
743
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
4.0
10.2
39
98
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
6.6
10.2
25
38
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
4.3
10.2
36
84
KH1AD
NOMESCO Finland
CT of urinary organs
2.5
10.2
80
332
UJF30
SPAT
NA
7.9
10.1
22
28
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
10.0
309
2082
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
14.6
10.0
16
11
JJ5AT
NOMESCO Finland
NA
40.2
10.0
12
*
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.2
10.0
102
478
J01CA04
ATC
amoxicillin; systemic
1.4
9.9
2032
18770
R03AC02
ATC
salbutamol; inhalant
1.3
9.9
1198
10267
S29
ICPC
Skin symptom/complaint other
1.5
9.9
331
2272
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
12.2
9.8
17
14
A02BA03
ATC
famotidine; systemic
2.6
9.8
70
274
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
6.3
9.8
25
40
R06.0
ICD-10 Finland
Dyspnoea
1.4
9.8
442
3227
N06AX21
ATC
duloxetine; oral
1.7
9.8
229
1436
K90.8
ICD-10 Finland
Other intestinal malabsorption
26.1
9.8
13
5
N32.1
ICD-10 Finland
Vesicointestinal fistula
26.1
9.8
13
5
Z43.2
ICD-10 Finland
Attention to ileostomy
20.1
9.8
14
7
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
20.1
9.8
14
7
A02BA04
ATC
nizatidine; systemic
1.9
9.7
134
711
56510
ICD-8 Finland
Anal fissure and fistula, Anal fistula
9.6
9.7
19
20
D82
ICPC
Teeth/gum disease
1.3
9.7
847
6918
1470
FHL
Rectoscopy
6.5
9.7
24
37
JFB40
NOMESCO Finland
Resection of transverse colon
55.2
9.6
11
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
9.6
145
795
SPAT1262
SPAT
Handing over of treatment supplies
1.5
9.6
323
2218
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
9.6
84
366
A03FA02
ATC
cisapride; oral, rectal
1.9
9.6
131
695
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
9.6
249
1610
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
8.4
9.5
20
24
K60.0
ICD-10 Finland
Acute anal fissure
3.8
9.5
38
100
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
9.5
128
676
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.9
9.5
55
191
ULA02
NOMESCO Finland
Kolposcopy
1.7
9.4
216
1348
JFA76
NOMESCO Finland
Closure of fistula of small intestine
100.4
9.4
10
*
RS221
NOMESCO Finland
NA
3.3
9.4
45
137
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
9.4
121
627
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
17.6
9.4
14
8
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
9.4
9
*
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
9.4
9
*
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
9.4
9
*
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
12.4
9.3
16
13
H26.3
ICD-10 Finland
Drug-induced cataract
6.9
9.3
22
32
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
9.3
620
4854
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.2
9.3
91
422
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.7
9.3
63
241
D29
ICPC
Digestive symptom/complaint other
3.0
9.3
51
172
N03AX16
ATC
pregabalin; oral
1.4
9.1
450
3342
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.9
9.1
36
94
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
9.1
696
5566
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
9.1
209
1309
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
9.0
320
2223
6525
FHL
Enterostomy occlusion
36.8
9.0
11
*
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
9.0
235
1517
N05CF02
ATC
zolpidem; oral
1.5
9.0
369
2645
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
2.9
9.0
53
187
R05
ICD-10 Finland
Cough
1.5
8.9
371
2663
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.1
8.9
47
154
L82
ICD-10 Finland
Seborrhoeic keratosis
1.6
8.9
258
1710
H20.1
ICD-10 Finland
Chronic iridocyclitis
3.8
8.9
36
96
R51.80
ICD-10 Finland
Headache
1.5
8.8
329
2312
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
8.8
236
1536
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.5
8.8
64
256
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
4.9
8.7
27
56
L43.8
ICD-10 Finland
Other lichen planus
3.3
8.7
42
130
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
8.6
127
692
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.6
8.6
28
61
M01AX17
ATC
nimesulide; oral
1.4
8.6
410
3024
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
5.5
8.6
24
44
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
8.6
455
3420
K63.8
ICD-10 Finland
Other specified diseases of intestine
16.3
8.5
13
8
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.2
8.5
43
137
M79.6
ICD-10 Finland
Pain in limb
1.3
8.5
722
5851
N05CF01
ATC
zopiclone; oral
1.4
8.5
584
4584
E000002
ATC
NA
1.5
8.5
262
1765
N05BA04
ATC
oxazepam; oral
1.4
8.4
496
3796
R53
ICD-10 Finland
Malaise and fatigue
1.4
8.4
378
2756
R35
ICD-10 Finland
Polyuria
2.0
8.4
109
565
Z01.2
ICD-10 Finland
Dental examination
1.3
8.4
982
8317
SPAT1255
SPAT
Intravenous administration of medicine
1.9
8.4
123
670
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
8.3
8
*
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
8.3
8
*
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
8.3
181
1116
N06AA09
ATC
amitriptyline; systemic
1.7
8.3
169
1023
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
9.5
8.3
16
17
L20.0
ICD-10 Finland
Besnier prurigo
1.7
8.2
175
1074
S21
ICPC
Skin texture symptom/complaint
1.6
8.1
229
1509
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
5.7
8.1
22
39
R01AD12
ATC
fluticasone furoate; nasal
1.3
8.1
709
5768
K85.3
ICD-10 Finland
Drug-induced acute pancreatitis
33.4
8.1
10
*
JN4BD
NOMESCO Finland
Extensive body CT
1.7
8.0
175
1081
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
8.0
496
3825
KBT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of ureter
8.9
8.0
16
18
S85
ICPC
Pilonidal cyst/fistula
10.0
8.0
15
15
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
5.0
8.0
24
48
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
8.0
235
1565
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
8.0
136
2155
M01AE01
ATC
ibuprofen; systemic, rectal
0.8
8.0
2045
21673
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
8.0
1290
11360
5650B
ICD-9 Finland
Anal fissure and fistula, Anal fissure[FISSURA ANI TYPICA]
7.2
7.9
18
25
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.5
7.9
59
240
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
7.9
871
7304
N06AX11
ATC
mirtazapine; oral
1.3
7.9
649
5229
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
1.6
7.9
211
1372
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
4.9
7.9
24
49
JEA00
NOMESCO Finland
Appendectomy
1.7
7.9
153
914
R2110
NOMESCO Finland
Giving the first information
1.7
7.9
146
860
A98
ICPC
Health maint/preventive medicine
1.7
7.8
2532
24571
SPAT1325
SPAT
Vaccination
1.3
7.8
629
5050
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.6
7.8
52
199
JFK00
NOMESCO Finland
Division of adhesive band in intestinal obstruction
10.8
7.8
14
13
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
7.8
337
2438
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.8
7.8
140
818
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
7.7
561
4435
WZA90
NOMESCO Finland
Other doctors statement
1.3
7.7
523
4089
N82.4
ICD-10 Finland
Other female intestinal-genital tract fistulae
45.1
7.7
9
*
JN2CM
NOMESCO Finland
Lower part of abdomen extensive MRI examination with Tesla magnet
5.3
7.7
22
42
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
7.6
46
166
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
7.6
1395
12440
JFB01
NOMESCO Finland
Laparoscopic partial resection of small intestine
18.4
7.6
11
6
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
11.9
7.6
13
11
ZX114
NOMESCO Finland
Intramuscular
3.0
7.5
40
134
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
4.1
7.5
27
66
SPAT1125
SPAT
Stoma care and guidance
4.1
7.5
27
66
D02AX
ATC
Other emollients and protectives
2.2
7.4
75
354
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
7.4
534
4212
J01MA14
ATC
moxifloxacin; systemic
1.7
7.4
157
960
4AB04
NOMESCO Finland
NA
80.3
7.4
8
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.3
7.4
67
300
TKC20
NOMESCO Finland
Catheterisation of bladder
1.9
7.4
107
581
-50
ICPC
Medication/prescr/renewal
2.1
7.4
84
416
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
7.4
61
261
7879X
ICD-9 Finland
Symptoms involving digestive system, Other symptoms involving digestive system
7.7
7.4
16
21
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.3
396
2985
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
2.8
7.3
43
153
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.3
1131
9867
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
+∞
7.3
7
*
6410
FHL
Panprococolectomy and ileostomy
+∞
7.3
7
*
M074, K508
ICD-10 Finland
NA
+∞
7.3
7
*
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
+∞
7.3
7
*
4AB0X
NOMESCO Finland
NA
+∞
7.3
7
*
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
7.3
7
*
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.3
7.3
63
275
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.5
7.3
238
1626
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.3
463
3582
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
5.2
7.2
21
41
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
0.6
7.2
143
2189
C03CA01
ATC
furosemide; systemic
1.4
7.2
326
2378
K60
ICD-10 Finland
Fissure and fistula of anal and rectal regions
15.8
7.2
11
7
R15
ICD-10 Finland
Faecal incontinence
2.9
7.2
42
148
L40.8
ICD-10 Finland
Other psoriasis
4.1
7.2
26
64
A02BX02
ATC
sucralfate; oral
2.2
7.2
66
300
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.2
593
4775
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
7.2
107
588
B01AA03
ATC
warfarin; systemic
1.5
7.2
237
1624
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.1
1126
9838
JFC20
NOMESCO Finland
Other enterocolostomy
30.1
7.1
9
*
N05BA01
ATC
diazepam; systemic, rectal
1.5
7.1
248
1715
6406
FHL
Other column resection
20.1
7.1
10
5
6451
FHL
Dilatation
6.6
7.1
17
26
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
7.1
118
673
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
7.9
7.1
15
19
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.5
7.1
51
205
-1
NOMESCO Finland
NA
1.3
7.1
809
6793
5781A
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[MELAENA]
12.0
7.1
12
10
JN2BG
NOMESCO Finland
MRI examination of lower part of abdoment with high intensity magnet
4.5
7.1
23
51
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.8
7.1
42
151
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
3.7
7.1
29
80
A01AB04
ATC
amphotericin B; local oral
2.1
7.0
77
378
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.7
7.0
45
168
JN2DM
NOMESCO Finland
Lower part of abdomen very extensive MRI examination with Tesla magnet
7.0
7.0
16
23
XJH00
NOMESCO Finland
Transanal ultrasonography
2.0
7.0
81
406
JHD10
NOMESCO Finland
Myotomy of anal sphincter
4.9
7.0
21
43
K83.1
ICD-10 Finland
Obstruction of bile duct
3.8
6.9
27
71
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
6.9
411
3143
G44.2
ICD-10 Finland
Tension-type headache
1.4
6.9
279
1989
M05BA07
ATC
risedronic acid; oral
2.6
6.9
46
177
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.9
1746
16069
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
6.9
190
1247
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.0
6.9
81
409
A55
ICPC
General and Unspecified, Local injection/infiltration
3.6
6.9
29
82
N19
ICD-10 Finland
Unspecified kidney failure
2.6
6.9
48
188
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
6.8
551
4416
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
3.1
6.8
34
109
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
6.8
823
6951
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.8
6.8
41
149
LEB00
NOMESCO Finland
Biopsy of vagina
2.9
6.8
39
135
6561
FHL
Removal of fasteners and related measures
10.9
6.8
12
11
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
40.1
6.8
8
*
K61.3
ICD-10 Finland
Ischiorectal abscess
16.7
6.7
10
6
K60.5
ICD-10 Finland
Anorectal fistula
16.7
6.7
10
6
K63.3
ICD-10 Finland
Ulcer of intestine
16.7
6.7
10
6
JGA98
NOMESCO Finland
Other transluminal endoscopic local operation on rectum
16.7
6.7
10
6
F43.29
ICD-10 Finland
Adaptation disorder UNS
2.3
6.7
55
237
ZQZ00
NOMESCO Finland
Treatment of several skin areas
7.2
6.7
15
21
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
7.2
6.7
15
21
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.7
6.7
130
780
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
3.1
6.6
34
112
A02BC04
ATC
rabeprazole; oral
1.6
6.6
173
1123
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
7.8
6.6
14
18
M79.7
ICD-10 Finland
Fibromyalgia
2.1
6.6
69
332
A07AA11
ATC
rifaximin; oral
12.3
6.6
11
9
JFG30
NOMESCO Finland
Closure of colostomy with resection of exteriorised loop
12.3
6.6
11
9
-69
ICPC
Other reason for encounter NEC
2.0
6.6
76
382
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
3.7
6.6
26
70
M05BA01
ATC
etidronic acid; systemic
8.7
6.5
13
15
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.8
6.5
98
540
D07AB08
ATC
desonide; topical
1.5
6.5
211
1440
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
10.0
6.5
12
12
N06AX16
ATC
venlafaxine; oral
1.4
6.5
311
2289
M01AX01
ATC
nabumetone; oral
2.1
6.5
73
361
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.5
6.5
47
190
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.5
6.5
229
1590
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
6.2
6.5
16
26
D84.18
ICD-10 Finland
Other specified defect in the complement system
70.0
6.4
7
*
K61.4
ICD-10 Finland
Intrasphincteric abscess
70.0
6.4
7
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.5
6.4
189
1261
E87.6
ICD-10 Finland
Hypokalaemia
2.4
6.4
49
203
D05AX52
ATC
calcipotriol, combinations; topical
1.8
6.4
106
603
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
3.9
6.4
24
62
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
6.4
175
1151
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
3.8
6.4
25
67
N87.0
ICD-10 Finland
Mild cervical dysplasia
2.2
6.4
58
264
E000007
ATC
NA
1.7
6.3
120
713
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.2
6.3
62
288
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
4.4
6.3
21
48
28009
ICD-8 Finland
Iron deficiency anaemias, Unspecified
8.2
6.3
13
16
TQW80
NOMESCO Finland
Local dermatologic skincare
2.3
6.3
52
225
B82
ICPC
Anaemia other/unspecified
2.6
6.3
43
169
D28
ICPC
Limited function/disability (D)
9.3
6.3
12
13
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
9.3
6.3
12
13
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.9
6.3
36
125
J01MA01
ATC
ofloxacin; systemic
1.7
6.3
133
818
M07.6
ICD-10 Finland
Other enteropathic arthropathies
+∞
6.2
6
*
M074K
ICD-10 Finland
NA
+∞
6.2
6
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
6.2
101
571
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
6.2
169
1108
JFA56
NOMESCO Finland
Faecal microbiota transplantation
26.7
6.2
8
*
A04AA01
ATC
ondansetron; systemic, rectal
1.7
6.2
120
719
L57.0
ICD-10 Finland
Actinic keratosis
1.8
6.2
104
596
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.1
6.2
68
334
K03.66
ICD-10 Finland
Tooth plaque
1.7
6.1
128
782
AA1AD
NOMESCO Finland
CT of head and brain
1.4
6.1
372
2855
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
4.2
6.1
21
50
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.2
6.1
21
50
WX723
NOMESCO Finland
CPAP therapy
2.0
6.1
70
350
R60.0
ICD-10 Finland
Localized oedema
1.6
6.1
160
1041
-44
ICPC
Preventive immunization/medic
1.6
6.1
136
847
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
6.1
197
1345
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
2.9
6.1
35
123
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
6.7
6.0
14
21
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
2.2
6.0
56
258
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.0
279
2042
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.1
6.0
65
318
D06
ICPC
Abdominal pain localized other
1.6
6.0
159
1036
N07BA03
ATC
varenicline; oral
1.7
6.0
115
685
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
6.0
234
1658
Mortality – FinRegistry
↥Association
Association between endpoint CHRONOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CHRONOTH | 1.589 [1.4, 1.81] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.559 |
During the follow-up period (1.1.1998 — 31.12.2019), 525 out of 6461 females with CHRONOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CHRONOTH | 1.474 [1.31, 1.66] | < 0.001 |
| Birth year | 0.985 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 669 out of 6316 males with CHRONOTH died.
Mortality risk
Mortality risk for people of age
years, who have CHRONOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.153% | 0.313% |
| 5 | 0.962% | 1.599% |
| 10 | 2.64% | 4.085% |
| 15 | 4.871% | 7.282% |
| 20 | 8.383% | 12.779% |
Relationships between endpoints
↥Index endpoint: CHRONOTH – Other Crohn's disease
GWS hits: 22
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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