endolymphatic hydrops: An accumulation of endolymph in the inner ear (labyrinth) leading to buildup of pressure and distortion of intralabyrinthine structures, such as cochlea and semicircular canals. It is characterized by sensorineural hearing loss; tinnitus; and sometimes vertigo.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3773 |
4. Check minimum number of eventsNone |
3773 |
5. Include endpointsNone |
3773 |
6. Filter based on genotype QC (FinnGen only) |
3773 |
Control definitions (FinnGen only)
- Control exclude
- H8_INNER
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H81
- Name in latin
- Morbus Ménière
Similar endpoints
↥List of similar endpoints to
Ménière disease
based on the number of shared cases.
Similar with more cases:
- Disorders of vestibular function (Vertigo)
- Diseases of inner ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 26706 | 17134 | 9455 |
| Only index persons | 24436 | 15945 | 8491 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.41 | 0.49 | 0.26 |
| Only index persons | 0.50 | 0.59 | 0.32 |
| Median age at first event (years) | |||
| Whole population | 57.15 | 57.45 | 56.61 |
| Only index persons | 56.64 | 56.87 | 56.19 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3773 | 2458 | 1315 |
| Unadjusted period prevalence (%) | 0.75 | 0.84 | 0.58 |
| Median age at first event (years) | 55.61 | 54.52 | 57.65 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3413
- Matched controls
- 34130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H81.3
ICD-10 Finland
Other peripheral vertigo
61.2
323.0
429
80
Z01.1
ICD-10 Finland
Examination of ears and hearing
6.4
323.0
1156
2528
N07CA01
ATC
betahistine; oral
100.9
323.0
2607
1061
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
15.2
323.0
631
503
R42
ICD-10 Finland
Dizziness and giddiness
7.6
323.0
1791
4329
H81.0
ICD-10 Finland
Ménière disease
13423.2
323.0
3225
42
DFF00
NOMESCO Finland
Pure tone audiometry
6.6
284.1
827
1586
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
8.2
257.5
625
910
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
4.2
250.7
1191
3857
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
4.2
239.4
1123
3567
N05AB04
ATC
prochlorperazine; systemic, rectal
13.0
202.4
373
320
38599
ICD-8 Finland
Ménière's disease
+∞
202.1
192
*
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
12.7
171.5
318
274
UDC00
NOMESCO Finland
Ear microscopy
5.5
162.2
524
1083
DFF59
NOMESCO Finland
Other assessment of balance
36.7
155.3
201
58
3860A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Ménière's disease
+∞
154.3
147
*
C03EA02
ATC
trichlormethiazide and potassium-sparing agents; oral
11.4
148.1
289
275
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
18.1
117.8
187
109
H81.2
ICD-10 Finland
Vestibular neuronitis
66.8
116.7
135
21
DFF15
NOMESCO Finland
Speech audiometry
5.4
106.4
344
696
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
4.1
94.0
406
1100
H93.1
ICD-10 Finland
Tinnitus
4.0
88.4
381
1028
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
78.2
923
4776
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
23.1
77.0
112
50
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
14.2
76.6
133
97
N17
ICPC
Vertigo/dizziness
2.9
75.9
535
2081
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.3
75.8
303
758
H02
ICPC
Hearing complaint
2.7
74.7
592
2470
DFF50
NOMESCO Finland
Electronystagmography
103.7
74.2
81
8
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.3
72.0
284
701
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
+∞
63.7
61
*
SPAT1043
SPAT
Audiometry
2.6
56.2
472
2011
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
54.3
491
2176
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
4.7
51.3
183
407
H02AB06
ATC
prednisolone; systemic
1.7
48.9
1639
11954
AA1AD
NOMESCO Finland
CT of head and brain
1.9
46.5
878
5311
R5120
NOMESCO Finland
Preparation of an aid
4.5
45.8
168
384
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
33.3
45.1
59
18
DC1AD
NOMESCO Finland
Temporalbone CT
9.8
44.8
92
96
H82
ICPC
Vertiginous syndrome
6.3
44.3
121
197
G44.2
ICD-10 Finland
Tension-type headache
2.2
42.7
492
2435
R51.80
ICD-10 Finland
Headache
2.1
38.7
499
2584
H91.9
ICD-10 Finland
Hearing loss, unspecified
3.3
38.5
206
654
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
4.3
37.5
145
350
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.6
37.3
295
1203
H80.9
ICD-10 Finland
Otosclerosis, unspecified
81.0
35.9
40
5
4173
FHL
Surgery on Saccus endolymphaticus
+∞
35.5
34
*
A02BC05
ATC
esomeprazole; systemic
1.6
34.5
1380
10212
DDA00
NOMESCO Finland
Stapedotomy
+∞
34.4
33
*
DFE00
NOMESCO Finland
Insertion of cochlear implant
20.7
34.4
51
25
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
33.9
741
4629
R01AD08
ATC
fluticasone; nasal
1.7
33.4
914
6102
DAX08
NOMESCO Finland
Fitting of hearing aid
3.0
33.0
201
698
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
5.1
32.7
105
209
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.6
31.9
150
431
R01AD09
ATC
mometasone; nasal
1.6
31.8
1400
10540
78050
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Vertigo
6.2
31.3
86
142
H29
ICPC
Ear symptom/complaint other
2.1
31.2
384
1941
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
31.2
360
1770
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
6.0
30.9
87
148
H80.1
ICD-10 Finland
Otosclerosis involving oval window, obliterative
+∞
27.1
26
*
M03BX02
ATC
tizanidine; oral
1.5
27.0
1935
15998
M25.5
ICD-10 Finland
Pain in joint
1.6
26.6
910
6377
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
26.0
775
5237
A02BC02
ATC
pantoprazole; systemic
1.5
25.8
2135
18100
A02BC03
ATC
lansoprazole; oral
1.5
25.8
995
7166
N02BE01
ATC
paracetamol; systemic, rectal
1.6
25.6
2858
25908
H13
ICPC
Plugged feeling ear
1.7
24.6
592
3766
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.2
24.6
267
1272
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
4.9
24.5
82
172
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
24.4
1107
8244
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
23.8
887
6312
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
23.7
967
7022
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
23.5
960
6974
R11
ICD-10 Finland
Nausea and vomiting
2.1
23.1
271
1337
R06AE53
ATC
cyclizine, combinations; systemic
6.1
22.7
62
103
H81.8
ICD-10 Finland
Other disorders of vestibular function
40.3
22.6
28
7
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
22.6
995
7340
DFX00
NOMESCO Finland
Connecting cochlear implant
24.0
22.1
31
13
J01DB01
ATC
cefalexin; oral
1.5
22.1
2609
23352
M54.5
ICD-10 Finland
Low back pain
1.5
21.4
984
7303
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.4
21.3
64
120
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
13.5
20.9
36
27
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
4.8
20.9
70
148
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.6
20.8
579
3814
H81.4
ICD-10 Finland
Vertigo of central origin
12.0
20.5
37
31
UJF32
NOMESCO Finland
Coloscopy
1.5
20.5
854
6200
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
20.3
1379
11035
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
20.0
618
4177
J01AA02
ATC
doxycycline; systemic
1.4
19.6
2546
22854
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
19.5
1860
15768
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
19.4
2087
18064
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
19.1
275
1471
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
19.1
507
3293
N03AX12
ATC
gabapentin; oral
1.6
19.1
495
3195
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
5.2
19.0
59
115
R03AC02
ATC
salbutamol; inhalant
1.4
18.9
1607
13318
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
18.6
325
1861
R06.0
ICD-10 Finland
Dyspnoea
1.5
18.6
789
5727
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
18.2
235
1205
J01CA04
ATC
amoxicillin; systemic
1.4
17.9
2506
22542
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
17.9
1540
12747
N06AX11
ATC
mirtazapine; oral
1.4
17.8
960
7303
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
17.8
1365
11076
DFA00
NOMESCO Finland
Saccotomy
+∞
17.7
17
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
17.4
367
2227
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
17.4
626
4375
M01AH05
ATC
etoricoxib; oral
1.4
17.3
1797
15311
C07AB07
ATC
bisoprolol; oral
1.4
16.9
1527
12698
SPAT1263
SPAT
Sampling
1.4
16.7
1292
10465
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
16.6
1645
13869
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.9
16.4
266
1486
J01FA06
ATC
roxithromycin; oral
1.4
16.3
1254
10133
M79.6
ICD-10 Finland
Pain in limb
1.4
16.3
1102
8711
K02.1
ICD-10 Finland
Caries of dentine
1.4
16.3
1583
13291
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
16.2
617
4360
J01MA02
ATC
ciprofloxacin; systemic
1.4
16.0
1198
9631
R01AD01
ATC
beclometasone; nasal
1.6
15.9
456
3013
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.4
15.9
76
225
J01FA10
ATC
azithromycin; systemic
1.3
15.8
1683
14307
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
15.4
1474
12305
H81
ICD-10 Finland
Disorders of vestibular function
10.1
15.4
30
30
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
15.3
1611
13649
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
4.3
15.2
56
132
XF404
NOMESCO Finland
Ambulatory ECG
1.7
15.2
308
1846
L01
ICPC
Neck symptom/complaint
1.6
15.2
408
2647
H53.1
ICD-10 Finland
Subjective visual disturbances
2.0
15.2
199
1027
M01AB05
ATC
diclofenac; systemic, rectal
1.3
15.0
2044
17987
R01AD12
ATC
fluticasone furoate; nasal
1.4
14.9
797
6020
J01DA01
ATC
[U] cefalexin; systemic
1.3
14.8
1936
16906
SPAT1153
SPAT
Removal of sutures
1.4
14.7
1002
7896
R53
ICD-10 Finland
Malaise and fatigue
1.5
14.7
605
4342
3861A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other and unspecified peripheral vertigo
+∞
14.6
14
*
M01AE02
ATC
naproxen; oral, rectal
1.3
14.6
1702
14604
L03
ICPC
Low back symptom/complaint
1.4
14.4
710
5275
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
14.3
1372
11420
Z01.2
ICD-10 Finland
Dental examination
1.4
14.2
1155
9364
R03BA05
ATC
fluticasone; inhalant
1.5
14.1
532
3744
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
14.1
1280
10557
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
14.0
301
1837
A98
ICPC
Health maint/preventive medicine
1.6
14.0
3137
29879
H92.0
ICD-10 Finland
Otalgia
2.2
14.0
149
707
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
13.9
513
3591
J01FA09
ATC
clarithromycin; systemic
1.4
13.9
909
7106
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
13.7
1055
8470
M01AX17
ATC
nimesulide; oral
1.4
13.6
798
6115
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
13.6
1103
8921
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
13.5
567
4072
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
13.5
474
3276
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.1
13.5
150
726
G43.9
ICD-10 Finland
Migraine, unspecified
2.1
13.4
146
697
N03AE01
ATC
clonazepam; systemic
1.9
13.4
186
984
J02AC01
ATC
fluconazole; systemic
1.3
13.4
1201
9863
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
13.3
1156
9444
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
13.3
410
2754
K30
ICD-10 Finland
Functional dyspepsia
1.7
13.2
307
1917
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
13.1
640
4735
N02AX02
ATC
tramadol; systemic, rectal
1.3
13.1
1283
10666
SPAT1097
SPAT
Recording of ECG
1.5
13.1
466
3231
J35.0
ICD-10 Finland
Chronic tonsillitis
2.3
13.0
119
527
A02BC01
ATC
omeprazole; systemic
1.4
13.0
855
6676
G47.3
ICD-10 Finland
Sleep apnoea
1.5
12.9
567
4108
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
12.9
787
6065
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
12.8
1267
10535
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
12.7
323
2065
3882A
ICD-9 Finland
Other disorders of ear, Sudden hearing loss, unspecified
9.7
12.7
25
26
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
12.6
1217
10083
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
12.5
1058
8585
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
12.5
736
5630
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
12.5
180
963
R55
ICD-10 Finland
Syncope and collapse
1.6
12.5
325
2092
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
12.3
1516
12977
R06AE07
ATC
cetirizine; oral
1.3
12.3
1267
10577
A02BC04
ATC
rabeprazole; oral
1.7
12.3
253
1526
Z97.8
ICD-10 Finland
Presence of other specified devices
7.1
12.3
29
41
KMAK
NOMESCO Finland
NA
1.3
12.2
1454
12382
N06AA09
ATC
amitriptyline; systemic
1.6
12.2
325
2102
SPAT1301
SPAT
No procedures
1.3
12.2
956
7666
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
12.1
213
1220
3891A
ICD-9 Finland
Deafness, Sensorineural deafness
15.9
12.1
19
12
N03AX16
ATC
pregabalin; oral
1.4
12.1
702
5354
DFF16
NOMESCO Finland
Speech-in-noise audiometry
12.4
12.1
21
17
C07AA05
ATC
propranolol; systemic
1.4
12.0
540
3926
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
12.0
233
1379
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
5.2
11.9
36
70
R07.3
ICD-10 Finland
Other chest pain
1.6
11.9
285
1795
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
11.9
288
1819
A02BA02
ATC
ranitidine; systemic
1.4
11.8
615
4597
L08
ICPC
Shoulder symptom/complaint
1.4
11.8
554
4061
WX110
NOMESCO Finland
Local anesthesy
1.3
11.7
2015
17993
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
11.6
393
2691
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
11.6
691
5292
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
11.5
694
5325
H83.1
ICD-10 Finland
Labyrinthine fistula
+∞
11.5
11
*
DE2CF
NOMESCO Finland
Acoustic channel extensive MRI examination with median intensity magnet
120.4
11.4
12
*
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
11.3
1143
9485
SGA01
NOMESCO Finland
Tooth opening as first aid
1.5
11.3
375
2555
TDA90
NOMESCO Finland
Removal wax from ear
3.5
11.3
51
147
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
11.2
330
2188
J01EA01
ATC
trimethoprim; systemic
1.4
11.2
792
6235
H91.8
ICD-10 Finland
Other specified hearing loss
4.1
11.2
42
103
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
11.2
807
6373
H02AB04
ATC
methylprednisolone; systemic
1.5
11.0
443
3148
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
11.0
176
978
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
10.9
396
2753
SPAT1216
SPAT
Assessment of functional ability
1.4
10.9
473
3418
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.1
10.8
123
602
SPAT1310
SPAT
Counselling related to known health issue
1.3
10.7
918
7429
UKC02
NOMESCO Finland
Cystoscopy
1.4
10.7
457
3287
SPAT1260
SPAT
Consultation of another employee
1.4
10.7
519
3827
R05
ICD-10 Finland
Cough
1.4
10.6
555
4145
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.9
10.5
151
811
R03DC03
ATC
montelukast; oral
1.4
10.5
447
3214
P01AB01
ATC
metronidazole; oral, rectal
1.3
10.5
1168
9797
H61.2
ICD-10 Finland
Impacted cerumen
1.8
10.4
171
960
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
10.4
230
1415
A04AA01
ATC
ondansetron; systemic, rectal
1.7
10.4
203
1204
3870A
ICD-9 Finland
Otosclerosis involving oval window, nonobliterative
+∞
10.4
10
*
M01AG02
ATC
tolfenamic acid; oral, rectal
1.5
10.4
433
3101
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
10.3
305
2022
SPAT1312
SPAT
General health counselling
1.3
10.3
905
7345
D82
ICPC
Teeth/gum disease
1.3
10.3
905
7346
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
10.3
177
1009
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
10.2
278
1809
R05
ICPC
Cough
1.4
10.1
620
4762
H01
ICPC
Ear pain/earache
1.6
10.1
266
1719
P06
ICPC
Sleep disturbance
1.6
10.0
247
1564
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
10.0
344
2360
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
10.0
1139
9570
RK520
NOMESCO Finland
NA
6.1
10.0
26
43
N06AB04
ATC
citalopram; systemic
1.4
9.9
624
4808
C03AA03
ATC
hydrochlorothiazide; oral
1.5
9.9
316
2136
R06AX27
ATC
desloratadine; oral
1.3
9.8
696
5462
N05BB51
ATC
hydroxyzine, combinations; systemic
8.7
9.8
20
23
S18
ICPC
Laceration/cut
1.3
9.7
1258
10729
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
9.7
2781
26195
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
9.7
650
5060
WZA90
NOMESCO Finland
Other doctors statement
1.4
9.6
611
4710
G04CA02
ATC
tamsulosin; oral
1.4
9.6
542
4097
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.6
9.6
255
1651
SPAT1104
SPAT
Monitoring of emergency patient
1.7
9.5
195
1175
R03AC03
ATC
terbutaline; inhalant
1.4
9.5
398
2849
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
9.5
138
746
-1
NOMESCO Finland
NA
1.3
9.4
861
7013
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.7
9.4
60
221
H80.8
ICD-10 Finland
Other otosclerosis
+∞
9.4
9
*
H28
ICPC
Limited function/disability (H)
3.8
9.4
38
101
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.7
9.3
193
1168
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.6
9.2
212
1321
L13
ICPC
Hip symptom/complaint
1.4
9.2
477
3555
WX290
NOMESCO Finland
Other blockade of nerve
1.3
9.1
1073
9025
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
9.1
510
3849
XF402
NOMESCO Finland
ECG with work load test
1.5
9.1
328
2278
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.1
9.0
105
520
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
9.0
1127
9552
M79.1
ICD-10 Finland
Myalgia
1.5
9.0
348
2453
R21
ICPC
Throat symptom/complaint
1.4
9.0
450
3333
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.5
8.9
318
2200
L02
ICPC
Back symptom/complaint
1.6
8.9
231
1487
R50.9
ICD-10 Finland
Fever, unspecified
1.5
8.9
365
2602
SPAT1325
SPAT
Vaccination
1.3
8.9
1037
8710
H81
ICPC
Excessive ear wax
1.4
8.9
467
3488
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.8
1317
11398
N06AX21
ATC
duloxetine; oral
1.5
8.8
292
1994
R12
ICD-10 Finland
Heartburn
1.6
8.6
199
1240
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.5
8.6
313
2177
H60.3
ICD-10 Finland
Other infective otitis externa
2.5
8.6
66
271
XQ800
NOMESCO Finland
Prick test
1.7
8.6
192
1189
34609
ICD-8 Finland
Migraine, Unspecified
4.2
8.6
31
75
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
8.5
575
4474
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.5
8.5
256
1710
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
8.4
415
3060
K04.0
ICD-10 Finland
Pulpitis
1.6
8.4
208
1323
H53.2
ICD-10 Finland
Diplopia
2.2
8.4
84
391
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.4
757
6143
J01CA08
ATC
pivmecillinam; oral
1.2
8.4
1222
10529
M54.2
ICD-10 Finland
Cervicalgia
1.7
8.4
182
1120
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.7
8.3
161
955
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
8.2
287
1979
M48.0
ICD-10 Finland
Spinal stenosis
1.4
8.2
363
2626
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
8.2
591
4639
A03FA02
ATC
cisapride; oral, rectal
1.6
8.2
235
1552
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.2
1190
10244
R03BA02
ATC
budesonide; inhalant
1.4
8.2
472
3581
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
8.1
267
1815
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
8.1
493
3769
H66.9
ICD-10 Finland
Otitis media, unspecified
1.9
8.1
121
663
SPAT1041
SPAT
Comprehensive hearing test
2.8
8.1
49
177
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
8.0
503
3863
M01AH01
ATC
celecoxib; oral (coxibs)
1.3
8.0
539
4187
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
2.8
8.0
48
172
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.6
8.0
210
1358
L86
ICPC
Back syndrome with radiating pain
1.7
7.9
156
931
C01CA24
ATC
epinephrine; parenteral
1.7
7.9
147
861
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.9
857
7114
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.7
7.9
147
866
DC1AI
NOMESCO Finland
Cone beam CT of ear
13.0
7.9
13
10
R4135
NOMESCO Finland
Rehabilitation for hearing problems
2.5
7.9
61
251
K07.60
ICD-10 Finland
Snapping jaw
1.8
7.9
119
654
R51
ICD-10 Finland
Headache
1.8
7.8
128
720
H03AA01
ATC
levothyroxine sodium; systemic
1.3
7.8
721
5864
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
7.7
436
3290
R06AX22
ATC
ebastine; oral
1.4
7.7
451
3429
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
7.7
694
5624
RK420
NOMESCO Finland
NA
8.0
7.6
16
20
M01AH02
ATC
rofecoxib; oral
1.4
7.6
400
2987
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.8
7.6
113
621
M01AC06
ATC
meloxicam; systemic, rectal
1.2
7.5
1079
9245
P01
ICPC
Feeling anxious/nervous/tense
1.6
7.5
186
1186
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
7.5
598
4762
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
3.7
7.4
30
81
H83.8
ICD-10 Finland
Other specified diseases of inner ear
80.2
7.4
8
*
4133
FHL
Stapedectomy sampling
80.2
7.4
8
*
A03
ICPC
Fever
1.4
7.4
352
2580
R35
ICD-10 Finland
Polyuria
1.7
7.4
162
999
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.3
599
4783
N06AX16
ATC
venlafaxine; oral
1.4
7.3
336
2447
TAB00
NOMESCO Finland
Lumbar puncture
1.8
7.3
109
598
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.0
7.3
90
459
38699
ICD-8 Finland
NA
+∞
7.3
7
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
1.8
7.3
118
666
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.7
7.3
143
857
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.3
7.3
642
5182
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.5
7.2
31
88
C10AA05
ATC
atorvastatin; oral
1.2
7.2
1141
9877
M54.3
ICD-10 Finland
Sciatica
1.6
7.1
163
1015
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
7.1
312
2254
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
7.1
361
2674
Z45.3
ICD-10 Finland
Adjustment and management of implanted hearing device
12.0
7.1
12
10
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.3
7.0
564
4492
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.2
7.0
1033
8872
M77.1
ICD-10 Finland
Lateral epicondylitis
1.6
7.0
163
1023
N03AX11
ATC
topiramate; oral
2.3
7.0
62
277
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
6.9
191
1251
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
6.9
864
7274
K04.1
ICD-10 Finland
Necrosis of pulp
1.5
6.9
248
1719
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.7
6.9
141
852
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.4
6.9
287
2051
UDM02
NOMESCO Finland
Sinoscopy
2.2
6.9
62
279
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
6.9
431
3310
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.1
6.9
69
325
SPAT1229
SPAT
Assessment of need for aid
1.5
6.9
236
1625
N06AB10
ATC
escitalopram; oral
1.3
6.9
474
3694
D33.30
ICD-10 Finland
Acoustic neuroma
3.7
6.8
28
77
C05AA08
ATC
fluocortolone; rectal, topical
1.4
6.8
397
3009
M01AC01
ATC
piroxicam; systemic, rectal
1.4
6.8
386
2921
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
6.7
1041
8974
G04BD12
ATC
mirabegron; oral
1.4
6.7
300
2175
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.6
6.7
172
1107
N05CF01
ATC
zopiclone; oral
1.2
6.7
949
8100
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
6.7
356
2663
C03BA04
ATC
chlortalidone; oral
22.5
6.7
9
*
C10AA07
ATC
rosuvastatin; oral
1.3
6.6
695
5727
ZXC10
NOMESCO Finland
Use of laser
2.3
6.6
57
251
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.6
648
5296
RK120
NOMESCO Finland
NA
5.5
6.6
18
33
A03CA02
ATC
clidinium and psycholeptics; oral
1.6
6.6
184
1207
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
3.5
6.6
28
80
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.6
6.6
143
884
C10AA01
ATC
simvastatin; oral
1.2
6.6
1332
11803
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
6.5
256
1811
N06AB06
ATC
sertraline; oral
1.4
6.5
256
1813
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
6.5
227
1570
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
1.8
6.5
98
543
A04
ICPC
Weakness/tiredness general
1.4
6.4
333
2480
H03
ICPC
Tinnitus, ringing/buzzing ear
2.3
6.4
56
249
M01AB08
ATC
etodolac; oral
1.5
6.4
206
1397
XA402
NOMESCO Finland
ENMG
2.0
6.4
73
365
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.0
6.4
77
393
M02AA10
ATC
ketoprofen; topical
1.3
6.4
451
3527
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.7
6.4
112
652
R00.2
ICD-10 Finland
Palpitations
1.6
6.3
175
1147
D07AC01
ATC
betamethasone; topical
1.2
6.3
942
8080
H83.3
ICD-10 Finland
Noise effects on inner ear
5.5
6.3
17
31
R83
ICPC
Respiratory infection other
1.3
6.3
507
4041
M02AA07
ATC
piroxicam; topical
1.2
6.2
1094
9536
DFD20
NOMESCO Finland
Closure of rupture of round window
+∞
6.2
6
*
M79.7
ICD-10 Finland
Fibromyalgia
1.9
6.2
88
477
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
3.2
6.2
30
95
S06.0
ICD-10 Finland
Concussion
1.4
6.2
242
1713
J01MA06
ATC
norfloxacin; oral
1.3
6.2
392
3014
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.5
6.2
209
1434
H02AB07
ATC
prednisone; oral
1.3
6.2
397
3062
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.2
6.2
728
6083
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
1.8
6.1
97
545
N63
ICD-10 Finland
Unspecified lump in breast
1.6
6.1
156
1003
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.6
6.1
153
982
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
6.1
630
5179
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.5
6.1
214
1482
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.6
6.1
140
879
I49.1
ICD-10 Finland
Atrial premature depolarization
1.8
6.1
89
488
C07AB02
ATC
metoprolol; systemic
1.3
6.1
620
5087
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
12.5
6.1
10
8
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
6.1
561
4550
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.4
6.1
326
2440
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
1.7
6.1
116
692
R06.5
ICD-10 Finland
Mouth breathing
1.5
6.0
203
1391
R03BC03
ATC
nedocromil; inhalant
1.5
6.0
190
1286
EMB10
NOMESCO Finland
Tonsillectomy
1.8
6.0
96
541
H82
ICD-10 Finland
Vertiginous syndromes in diseases classified elsewhere
10.0
6.0
11
11
L16
ICPC
Ankle symptom/complaint
1.4
6.0
252
1807
N01
ICPC
Headache
1.5
6.0
204
1401
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.2
6.0
719
6014
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2806
23579
1.74
46.51
4.8
4.2
11.8
13.3
mm/h
6.51
2623
21682
1374
9892
1.61
40.29
2.1
2.1
137.6
207.3
u/l
4.85
1275
9235
1615
12398
1.53
34.03
4.1
3.8
38.8
89.2
ng/l
0.76
1104
8807
1347
10089
1.52
31.03
2.4
2.5
56.1
57.6
u/l
0.36
1232
9281
3387
31114
1.87
29.38
16.7
15.1
21.8
24.3
mg/l
4.04
2781
24840
2827
24863
1.55
28.41
7.6
7.6
76.6
79.4
u/l
3.16
2636
23336
2247
18903
1.47
27.70
4.3
4.6
6.7
6.8
mmol/l
1.33
2136
17722
2470
21219
1.48
26.94
5.1
4.8
500.3
2400.9
e6/l
2.54
44
299
3176
28845
1.64
26.26
5.7
5.0
1.9
2.1
mu/l
1.00
2917
26221
3477
32437
1.92
25.45
18.9
17.5
139.6
139.7
mmol/l
0.43
3411
31617
3479
32526
1.89
24.34
19.1
17.6
3.9
4.0
mmol/l
7.00
3408
31658
3182
29059
1.61
24.03
6.2
6.0
39.7
40.1
mmol/mol
1.86
2904
26688
2745
24324
1.47
23.57
4.7
4.2
15.0
14.9
pmol/l
2.00
2485
21973
2016
16950
1.41
22.75
5.4
6.2
11.2
11.4
umol/l
0.52
1903
16076
1825
15100
1.40
22.52
5.0
5.9
1.2
1.2
mmol/l
3.42
1639
13612
1972
16667
1.38
20.72
5.9
6.7
1.2
1.2
mmol/l
3.62
1664
14003
348
2059
1.76
20.26
2.5
2.4
45.9
24.5
au/ml
0.72
12
93
3500
33041
1.82
20.04
11.8
10.8
24.9
25.2
u/l
0.43
3378
31772
3284
30535
1.58
19.40
5.2
4.8
5.9
6.0
mmol/l
0.93
2996
27629
3494
33014
1.79
19.29
19.4
17.8
77.2
77.0
umol/l
0.10
3494
33000
3344
31336
1.59
17.82
5.6
5.1
2.7
2.7
mmol/l
0.07
3062
28592
3281
30647
1.54
17.36
5.0
4.5
4.6
4.7
mmol/l
0.80
3010
28116
311
1862
1.73
17.32
1.3
1.3
68.2
45.2
au/ml
0.44
11
87
2243
19640
1.35
17.32
3.2
3.1
49.3
50.1
u/l
0.18
2075
18091
517
3515
1.55
17.27
2.2
2.1
108.9
134.6
ug/g
1.32
414
2717
3259
30407
1.53
17.24
4.9
4.5
1.5
1.5
mmol/l
2.11
2970
27717
3577
34181
1.89
17.02
24.7
22.4
251.2
251.5
e9/l
0.11
3507
33254
576
4027
1.51
16.87
4.9
4.6
33.0
33.1
%
0.07
410
2666
3578
34203
1.89
16.86
24.9
22.5
134.7
133.5
g/l
6.04
3533
33654
1227
9834
1.37
16.85
3.1
3.0
1293.5
1519.5
ng/l
0.62
1046
8454
3577
34193
1.89
16.82
24.7
22.4
4.5
4.4
e12/l
4.71
3495
33146
3577
34197
1.89
16.75
24.8
22.4
6.7
6.7
e9/l
0.08
3495
33143
3161
29355
1.47
16.64
4.4
4.0
1.3
1.3
mmol/l
0.58
2851
26528
1811
15443
1.33
16.29
4.1
3.9
0.0
0.0
estimate
0.00
306
2841
1894
16259
1.33
16.25
6.0
6.0
0.2
0.2
e9/l
0.12
1666
14169
856
6501
1.41
16.15
1.3
1.2
1.3
1.6
u/ml
0.52
208
1694
673
4909
1.45
15.84
1.9
2.1
29.2
29.9
s
2.66
646
4763
1808
15486
1.32
15.44
5.5
5.2
0.0
0.0
estimate
0.80
315
2870
1862
16037
1.32
15.18
5.9
5.8
1.9
1.9
e9/l
0.32
1649
14016
888
6862
1.38
14.96
1.9
1.8
1.1
1.3
mg/l
0.56
673
5286
1820
15671
1.31
14.67
4.2
3.9
0.0
0.0
estimate
0.63
314
2824
717
5365
1.42
14.55
1.3
1.3
28.8
34.1
iu/ml
0.75
208
1678
681
5107
1.41
13.55
1.3
1.2
10.4
12.3
u/ml
0.31
248
1907
1035
8310
1.34
13.40
2.6
2.7
3968.3
5546.0
umol/l
0.66
892
7123
1703
14676
1.29
13.06
6.3
6.0
2.8
2.8
%
0.12
1585
13602
2073
18341
1.29
12.87
8.4
9.1
4.1
4.1
e9/l
0.01
1815
15978
1742
15085
1.29
12.75
6.5
6.1
28.1
27.5
%
1.57
1608
13968
1718
14858
1.29
12.68
6.1
5.9
57.0
57.6
%
1.19
1597
13814
1665
14347
1.29
12.63
4.2
4.7
35.8
35.2
g/l
5.30
1530
13291
733
5654
1.37
12.18
1.5
1.5
2.3
2.5
g/l
1.33
414
3338
809
6337
1.35
12.17
4.1
3.8
218.7
386.0
ng/l
1.27
636
5098
1593
13714
1.28
11.94
2.1
2.0
98.7
95.2
pmol/l
1.84
789
6885
1978
17532
1.27
11.51
2.9
2.7
—
—
—
0
0
1387
11833
1.27
10.88
4.5
4.2
—
—
—
0
0
3122
29454
1.35
10.54
15.0
14.2
77.7
77.7
ml/min/173m2
0.04
2635
24414
1515
13138
1.26
10.14
2.9
2.8
123.9
129.0
ug/l
0.23
1384
12071
402
2892
1.44
9.94
2.1
2.2
373.7
374.3
nmol/l
0.02
367
2638
833
6786
1.29
9.16
4.7
4.4
1.0
1.0
kg/l
1.80
146
1037
1327
11458
1.24
8.90
2.9
3.4
2.4
2.4
mmol/l
0.05
1107
9934
566
4403
1.34
8.66
27.2
25.9
1.4
1.4
inr
0.41
95
605
147
876
1.71
8.42
1.3
1.2
15.2
43.8
u/ml
1.24
12
56
241
1625
1.52
8.28
2.5
2.7
0.1
0.3
e6/l
3.46
232
1581
1541
13609
1.22
8.15
2.4
2.2
80.1
79.3
nmol/l
0.52
1382
12112
260
1792
1.48
8.04
1.3
1.3
250.0
195.6
u/ml
0.28
247
1634
321
2309
1.43
7.94
3.0
2.8
10.0
10.5
g/l
1.52
295
2102
984
8330
1.25
7.66
2.4
2.2
2.9
3.0
mg/l
0.67
854
7063
116
669
1.76
7.50
1.2
1.2
3.2
3.4
u/ml
—
7
54
81
420
1.95
7.34
2.6
2.2
25.2
23.6
mg/l
0.09
27
103
471
3653
1.33
7.31
2.4
2.6
9.4
8.4
umol/l
0.31
414
3161
11
16
6.89
7.15
1.8
1.4
15.8
37.5
pmol/l
0.47
11
11
128
773
1.68
7.04
1.1
1.1
5.6
6.8
u/ml
—
5
83
132
808
1.66
6.90
1.3
1.2
2.2
6.1
u/ml
0.58
12
92
182
1207
1.53
6.80
1.3
1.2
1.3
1.5
u/ml
0.08
22
110
133
820
1.64
6.77
1.3
1.3
6.9
7.6
u/ml
0.05
19
145
151
961
1.60
6.76
1.7
1.8
—
—
—
0
0
778
6520
1.24
6.50
1.7
1.8
1116.8
1177.4
nmol/l
1.12
601
4899
545
4383
1.28
6.45
1.5
1.4
—
—
—
0
0
962
8262
1.22
6.35
5.5
5.2
3.9
3.6
ug/l
0.09
872
7342
45
197
2.30
6.35
1.0
1.1
271.6
281.3
mg/l
0.13
40
167
44
191
2.32
6.33
1.1
1.1
—
—
—
0
0
142
911
1.58
6.17
1.7
1.7
—
—
—
0
0
271
1986
1.39
6.06
3.2
3.7
5.1
5.2
kpa
0.60
249
1835
970
8379
1.21
5.99
4.8
4.3
0.0
0.0
estimate
0.26
309
2784
45
204
2.22
5.87
1.1
1.1
35.3
41.5
mg/l
0.57
40
170
258
1886
1.39
5.86
3.2
3.6
1.6
2.0
mmol/l
0.89
188
1418
207
1459
1.44
5.77
1.0
1.0
—
—
—
0
0
175
1200
1.48
5.63
3.7
3.9
25.0
24.9
mmol/l
0.12
161
1100
362
2819
1.31
5.46
2.7
2.7
66.2
66.4
g/l
0.23
332
2568
43
198
2.19
5.43
1.8
1.7
17.2
17.0
nmol/l
0.07
43
182
1141
10095
1.19
5.32
3.1
3.2
30.1
36.8
u/l
2.87
1068
9551
39
174
2.25
5.32
1.2
1.5
5.1
7.3
u/l
1.23
33
152
81
470
1.74
5.24
1.3
1.3
0.2
0.4
nmol/l
—
5
31
57
299
1.92
5.10
1.0
1.1
—
5.4
—
0
5
1146
10175
1.18
5.08
4.0
3.9
7.2
8.7
mg/mmol
0.53
645
6294
134
893
1.52
4.99
2.1
1.6
0.2
0.2
g/l
0.24
129
848
772
6630
1.21
4.96
4.9
4.4
22.0
21.8
%
0.15
375
3337
645
5443
1.22
4.95
1.9
1.8
—
—
—
0
0
51
261
1.97
4.92
1.0
1.1
—
—
—
0
0
895
7799
1.19
4.90
1.5
1.6
20.6
20.7
nmol/l
0.07
758
6635
136
921
1.49
4.71
2.0
1.6
1.2
1.2
g/l
0.14
131
877
1120
9981
1.17
4.68
3.2
3.1
7.1
7.1
mmol/l
0.12
931
8346
335
2638
1.30
4.68
2.9
3.6
76.7
90.4
ng/l
3.06
283
2249
370
2955
1.28
4.63
3.2
3.0
212.1
211.0
ng/l
0.01
347
2700
51
268
1.92
4.58
1.3
1.2
112.0
67.5
u/ml
—
5
11
1634
15014
1.16
4.54
4.0
4.0
—
—
—
0
0
51
271
1.89
4.44
1.3
1.2
24.5
55.3
u/ml
—
6
25
255
1949
1.33
4.43
3.3
3.3
4.4
4.4
pmol/l
0.30
226
1712
2876
27582
1.18
4.42
17.3
16.4
39.1
39.1
%
0.00
1882
18790
497
4141
1.23
4.30
8.0
7.4
—
—
—
0
0
35
164
2.14
4.30
1.2
1.5
5.9
8.9
ug/l
1.60
30
141
785
6838
1.19
4.26
2.5
2.6
4.4
5.9
e6/l
4.29
674
5989
63
364
1.74
4.21
1.5
1.4
31.8
32.4
u/l
0.04
50
303
149
1054
1.43
4.17
1.6
1.6
80.0
284.6
titre
—
7
52
65
384
1.70
4.03
1.3
1.3
88.7
53.6
u/ml
—
8
24
96
628
1.54
3.97
1.3
1.2
52.6
43.9
u/ml
0.13
11
70
36
178
2.03
3.88
1.1
1.1
0.3
6.6
nmol/l
—
7
39
1003
8996
1.16
3.72
3.1
3.1
0.4
0.5
e6/l
0.73
759
6821
175
1300
1.36
3.71
1.7
1.8
38.7
39.1
u/l
0.11
159
1148
620
5361
1.19
3.64
3.0
3.2
0.8
0.8
mmol/l
0.93
557
4984
136
974
1.41
3.60
1.4
1.4
286.9
276.4
ug/g
0.22
83
557
171
1278
1.35
3.51
2.0
1.8
—
—
—
0
0
882
7869
1.16
3.49
2.3
2.3
—
—
—
0
0
84
551
1.54
3.47
2.0
1.8
5578.1
3747.3
u/l
0.16
25
211
184
1393
1.34
3.47
2.2
1.9
—
—
—
0
0
592
5128
1.18
3.40
2.3
2.5
13.4
12.7
umol/l
1.26
546
4741
181
1372
1.34
3.39
4.7
5.6
1.6
1.6
%
0.18
169
1283
442
3730
1.21
3.39
3.7
4.2
242.1
248.6
u/l
0.40
411
3517
352
2903
1.23
3.38
2.5
2.4
6.9
6.7
ug/l
0.04
300
2535
811
7251
1.15
3.09
1.6
1.7
550.4
30810886.1
pmol/l
5.44
672
5972
93
642
1.46
3.05
1.2
1.4
12.5
29.8
e6/l
0.94
81
489
16
62
2.59
3.04
1.1
1.1
—
—
—
0
0
84
569
1.49
3.03
1.5
1.3
11.9
12.8
u/l
0.26
72
455
93
644
1.46
3.01
1.3
1.4
1002.1
1505.0
e6/l
0.24
82
521
147
1103
1.35
2.99
2.6
2.7
—
—
—
0
0
175
1352
1.31
2.92
1.9
2.0
2.4
2.4
ug/l
0.00
144
1193
245
1977
1.26
2.90
1.2
1.2
106.7
155.1
iu/ml
1.47
102
721
295
2431
1.23
2.89
1.6
1.6
—
—
—
0
0
19
83
2.30
2.83
1.1
1.1
98.4
85.5
%
—
10
44
18
77
2.34
2.81
1.1
1.2
—
—
—
0
0
259
2112
1.24
2.80
6.1
7.0
24.9
24.6
mmol/l
0.53
240
1963
31
165
1.89
2.80
1.9
1.7
—
—
—
0
0
31
165
1.89
2.80
1.9
1.7
—
—
—
0
0
31
165
1.89
2.80
1.9
1.7
—
—
—
0
0
31
165
1.89
2.80
1.9
1.7
—
—
—
0
0
102
730
1.41
2.79
2.2
2.3
138.5
127.2
g/l
4.47
72
531
175
1365
1.30
2.74
4.8
5.6
0.9
0.9
%
1.13
164
1278
50
311
1.62
2.67
2.1
2.8
—
—
—
0
0
34
190
1.80
2.66
1.4
1.3
—
—
—
0
0
488
4249
1.17
2.65
4.0
5.6
1.0
1.0
mmol/l
2.20
448
3923
34
192
1.78
2.58
1.4
1.3
—
—
—
0
0
63
419
1.51
2.54
1.6
1.4
—
—
—
0
0
18
81
2.23
2.53
1.2
1.1
221.9
320.0
pmol/l
1.06
13
62
930
8507
1.12
2.45
1.8
1.6
1.4
1.4
mmol/l
0.09
779
7081
26
137
1.90
2.45
1.1
1.3
—
—
—
0
0
199
1602
1.26
2.45
2.2
2.2
11.8
12.2
nmol/l
0.28
178
1394
25
131
1.91
2.40
2.1
1.8
—
—
—
0
0
25
131
1.91
2.40
2.1
1.8
—
—
—
0
0
618
5517
1.14
2.39
2.8
2.7
1.2
1.2
e6/l
0.17
390
3174
63
425
1.49
2.39
1.6
1.4
—
—
—
0
0
12
46
2.61
2.35
1.3
1.2
—
—
—
0
0
25
132
1.90
2.35
2.2
1.8
—
—
—
0
0
432
3764
1.17
2.34
1.7
1.8
—
—
—
0
0
142
1104
1.30
2.32
1.4
1.3
30.2
33.8
iu/l
0.67
120
946
108
809
1.34
2.30
1.9
2.0
13.6
11.8
mg/l
0.18
99
741
243
2021
1.22
2.24
1.7
1.6
—
—
—
0
0
35
210
1.67
2.19
1.3
1.3
—
—
—
0
0
16
74
2.17
2.14
1.0
1.1
0.9
0.7
umol/24h
—
6
38
59
403
1.47
2.14
1.2
1.3
289.0
277.6
pmol/l
0.13
47
320
430
3777
1.16
2.11
1.7
1.7
—
—
—
0
0
65
454
1.44
2.11
1.4
1.6
—
—
—
0
0
230
1915
1.21
2.11
1.7
1.5
—
—
—
0
0
34
205
1.66
2.10
1.3
1.3
—
—
—
0
0
39
244
1.60
2.09
1.7
1.5
24.1
17.8
u/ml
0.39
12
50
705
6402
1.12
2.09
2.8
3.1
2.5
2.5
mmol/l
0.47
591
5598
427
3755
1.15
2.07
2.5
2.5
1.8
1.8
%
0.15
383
3318
17
82
2.08
2.06
1.0
1.3
107.9
81.4
%
—
9
44
99
747
1.33
2.04
1.3
1.3
—
—
—
0
0
60
416
1.45
2.03
1.6
1.4
—
—
—
0
0
94
705
1.34
2.02
2.1
3.0
8.4
7.9
kpa
2.07
87
653
26
148
1.76
1.98
1.3
1.4
—
—
—
0
0
26
148
1.76
1.98
1.3
1.4
—
—
—
0
0
50
339
1.48
1.91
1.9
1.6
—
—
—
0
0
60
422
1.43
1.90
1.6
1.4
—
—
—
0
0
19
99
1.92
1.90
1.2
1.2
0.3
0.3
g/l
0.63
14
80
164
1336
1.24
1.88
1.7
2.5
—
—
—
0
0
59
415
1.43
1.88
1.6
1.4
—
—
—
0
0
59
415
1.43
1.88
1.6
1.4
—
—
—
0
0
164
1337
1.24
1.87
1.7
2.5
7.4
7.5
g/l
0.06
118
1000
8
28
2.86
1.86
1.3
1.0
—
—
—
0
0
36
230
1.57
1.81
1.2
1.2
—
—
—
0
0
414
3670
1.14
1.81
3.4
4.0
12.1
26.8
ug/l
1.16
334
2989
163
1335
1.23
1.80
1.7
2.5
3.9
3.8
g/l
0.28
109
953
196
1636
1.21
1.79
3.3
3.1
25.6
25.4
mmol/l
0.51
190
1584
36
231
1.56
1.78
1.2
1.2
—
—
—
0
0
524
4724
1.13
1.77
2.2
2.5
2.4
2.3
g/l
2.97
478
4362
29
177
1.64
1.76
1.1
1.0
—
—
—
0
0
36
232
1.56
1.75
1.2
1.2
—
—
—
0
0
36
232
1.56
1.75
1.2
1.2
—
—
—
0
0
36
232
1.56
1.75
1.2
1.2
—
—
—
0
0
563
5101
1.12
1.75
3.0
2.9
3.6
2.9
e6/l
0.63
338
2778
15
74
2.03
1.74
2.7
2.4
—
—
—
0
0
35
226
1.55
1.70
1.0
1.0
706.9
706.8
ng/l
0.00
25
139
35
226
1.55
1.70
1.0
1.0
303.9
323.7
ng/l
0.18
27
142
12
55
2.19
1.67
1.2
1.4
84.3
104.8
ng/l
0.43
12
55
8
31
2.58
1.66
1.0
1.0
—
—
—
0
0
152
1249
1.23
1.65
1.7
2.5
3.0
3.1
g/l
0.66
111
978
35
228
1.54
1.64
1.0
1.0
44.9
45.4
ng/l
0.02
26
140
48
335
1.44
1.63
3.4
3.4
51.1
57.4
%
0.91
33
216
21
120
1.75
1.62
1.0
1.2
—
—
—
0
0
489
4416
1.12
1.61
2.3
2.6
22.4
22.4
%
0.01
391
3747
42
287
1.47
1.59
1.7
1.6
—
—
—
0
0
42
287
1.47
1.59
1.7
1.6
—
—
—
0
0
42
287
1.47
1.59
1.7
1.6
—
—
—
0
0
27
168
1.61
1.55
1.0
1.0
1.0
1.1
u/l
0.83
13
93
122
988
1.24
1.53
1.3
1.3
—
—
—
0
0
93
729
1.28
1.53
1.2
1.1
—
—
—
0
0
38
260
1.47
1.45
1.2
1.5
—
—
—
0
0
31
203
1.53
1.45
1.5
1.3
33.3
75.9
titre
—
6
17
89
702
1.27
1.42
2.7
2.6
18.3
15.9
%
5.28
51
361
112
908
1.24
1.42
1.5
1.6
0.1
7.0
iu/ml
0.59
17
199
10
46
2.18
1.39
1.6
1.2
—
—
—
0
0
59
441
1.34
1.39
1.3
1.4
—
—
—
0
0
231
2008
1.16
1.38
3.0
3.0
128.3
127.6
g/l
0.23
224
1957
422
3819
1.12
1.37
4.7
7.0
12.4
12.2
kpa
0.22
396
3635
136
1132
1.21
1.35
1.7
2.6
0.8
1.1
g/l
0.52
115
980
10
47
2.13
1.33
1.0
1.1
—
—
—
0
0
0
40
0.00
1.32
0.0
13.3
—
5.4
—
0
40
38
266
1.43
1.32
1.2
1.2
—
—
—
0
0
26
168
1.55
1.31
1.3
1.7
4.2
1.9
u/field
0.65
17
117
102
827
1.24
1.31
2.1
3.3
25.1
25.1
mmol/l
0.04
86
720
421
3821
1.11
1.31
4.7
7.0
5.1
5.1
kpa
0.39
396
3639
420
3815
1.11
1.29
4.7
7.0
1.3
1.2
mmol/l
0.25
323
2966
522
4797
1.10
1.28
3.1
3.1
0.8
0.8
ug/l
0.11
345
3288
9
44
2.05
1.26
1.0
1.0
—
—
—
0
0
21
130
1.62
1.26
1.3
1.1
—
—
—
0
0
48
354
1.36
1.25
1.0
1.1
—
—
—
0
0
98
796
1.24
1.25
1.8
1.8
3.4
4.6
iu/l
1.78
35
270
8
158
0.51
1.24
1.0
1.3
—
—
—
0
0
6
25
2.40
1.24
1.3
1.2
—
—
—
0
0
13
70
1.86
1.23
1.0
1.0
—
—
—
0
0
188
2165
0.86
1.22
1.8
1.8
—
—
—
0
0
44
322
1.37
1.21
2.0
1.6
—
—
—
0
0
27
180
1.50
1.20
1.1
1.1
95.9
82.7
u/l
0.48
21
131
27
180
1.50
1.20
1.1
1.1
26.0
26.4
u/l
0.02
20
127
6
26
2.31
1.18
1.2
1.2
—
—
—
0
0
8
39
2.05
1.15
1.0
1.1
—
—
—
0
0
71
563
1.27
1.13
1.2
1.2
—
—
—
0
0
18
111
1.62
1.12
1.2
1.1
1610.4
436.7
ng/l
—
5
28
146
1249
1.18
1.11
1.9
2.5
10.1
10.3
g/l
0.38
121
1058
46
345
1.34
1.11
1.2
1.3
7.8
7.6
mmol/l
0.13
33
249
30
209
1.44
1.10
1.2
1.8
16.4
9.6
umol/l
0.21
19
144
118
994
1.19
1.08
1.6
2.4
0.0
0.0
g/l
0.00
106
911
91
749
1.22
1.06
1.5
1.3
—
—
—
0
0
530
4923
1.09
1.06
1.4
1.4
—
—
—
0
0
31
430
0.72
1.05
3.7
4.9
361.6
355.9
umol/l
0.08
24
373
12
67
1.79
1.04
1.5
1.4
—
—
—
0
0
23
154
1.50
1.03
1.0
1.1
—
—
—
0
0
38
283
1.35
0.98
1.2
1.6
—
—
—
0
0
129
1107
1.17
0.98
2.9
3.5
45.0
63.9
mg/l
0.48
108
907
129
1107
1.17
0.98
2.9
3.5
33.5
107.9
mg/l
0.84
109
909
110
933
1.18
0.96
1.5
1.7
—
—
—
0
0
40
302
1.33
0.95
4.0
5.0
15.4
59.1
u/ml
2.42
11
83
43
329
1.31
0.94
2.6
1.4
26.2
21.3
iu/ml
—
5
15
22
150
1.47
0.92
1.3
1.4
17.5
23.0
umol/l
0.49
22
141
171
1507
1.14
0.92
2.4
2.5
0.7
0.7
%
0.02
161
1438
287
2612
1.11
0.91
2.6
2.6
68.3
63.5
ml/min/173m2
1.38
110
1069
328
3007
1.10
0.90
2.8
3.5
1.8
2.0
mmol/l
0.81
276
2440
11
63
1.75
0.90
1.2
1.3
—
—
—
0
0
23
160
1.44
0.88
2.1
2.4
—
—
—
0
0
83
693
1.20
0.88
3.9
3.5
28.9
27.6
mg/l
0.10
52
431
110
943
1.17
0.87
1.2
1.2
—
—
—
0
0
46
360
1.28
0.87
1.2
1.2
53.8
59.5
u/l
0.41
30
253
78
650
1.20
0.85
1.6
1.6
—
—
—
0
0
66
541
1.22
0.85
4.0
3.6
1.3
1.5
%
0.25
50
423
65
532
1.23
0.85
1.2
1.2
35.7
35.3
u/l
0.01
58
457
26
187
1.39
0.85
2.9
2.2
646.5
727.2
e6/l
0.24
15
73
17
112
1.52
0.84
1.4
2.4
180.7
144.6
umol/l
—
7
61
120
1040
1.16
0.84
1.6
2.3
38.2
37.5
g/l
0.58
103
890
29
214
1.36
0.82
2.0
1.9
13.0
14.7
%
0.33
13
86
94
801
1.18
0.81
1.8
1.5
—
—
—
0
0
1437
13922
1.05
0.81
10.2
9.8
0.0
0.0
e9/l
1.16
1209
11344
160
1420
1.13
0.80
1.4
1.3
—
—
—
0
0
65
784
0.83
0.80
2.3
2.3
81.9
98.6
ug/min
0.15
43
470
329
3037
1.09
0.80
2.3
2.3
33.2
39.1
u/l
0.92
279
2589
19
271
0.70
0.80
1.3
1.5
—
—
—
0
0
328
3028
1.09
0.79
2.8
3.5
5.7
5.9
kpa
1.49
322
2934
45
564
0.80
0.79
1.3
1.5
—
—
—
0
0
6
33
1.82
0.79
8.8
4.4
—
—
—
0
0
0
25
0.00
0.79
0.0
1.3
—
—
—
0
0
16
235
0.68
0.78
1.8
1.7
—
—
—
0
0
332
3070
1.09
0.78
1.5
1.7
1.5
1.5
%
0.20
290
2666
12
187
0.64
0.78
1.4
1.5
—
—
—
0
0
40
313
1.28
0.77
1.1
1.1
—
2.9
—
0
5
28
208
1.35
0.77
1.3
1.3
0.1
0.9
u/ml
1.01
15
102
35
270
1.30
0.76
1.1
1.1
7.3
2.5
u/ml
0.35
13
104
71
595
1.20
0.75
1.9
1.6
—
—
—
0
0
14
91
1.54
0.75
1.4
1.3
36.3
33.4
%
—
8
60
51
414
1.24
0.74
1.2
1.1
2.5
1.7
u/ml
0.14
18
168
7
38
1.84
0.73
1.0
1.2
1.5
1.7
umol/24h
—
7
38
77
653
1.18
0.73
1.3
1.3
145.6
214.4
miu/ml
1.35
30
288
8
136
0.59
0.72
7.6
11.6
0.6
0.6
mmol/l
—
8
124
117
1027
1.14
0.72
4.0
3.8
3.9
3.9
mmol/l
0.39
112
963
49
398
1.23
0.71
1.4
1.5
50.3
60.8
%
0.88
27
245
59
708
0.83
0.71
1.7
1.5
—
—
—
0
0
125
1103
1.14
0.71
1.8
2.2
234.1
683.2
ug/l
1.58
113
1032
7
41
1.71
0.70
2.3
2.2
—
—
—
0
0
7
41
1.71
0.70
2.3
2.2
—
—
—
0
0
106
927
1.15
0.69
1.6
2.5
0.0
0.0
g/l
0.80
94
848
70
592
1.19
0.69
6.3
4.8
217.6
611.1
iu/ml
0.92
12
80
5
27
1.85
0.68
1.0
1.7
—
—
—
0
0
45
365
1.24
0.67
1.1
1.1
1.9
3.7
u/ml
0.77
13
146
21
153
1.37
0.67
1.0
1.1
—
—
—
0
0
85
981
0.86
0.66
1.7
1.7
3.1
3.6
mg/l
0.31
58
712
49
403
1.22
0.65
1.1
1.1
—
—
—
0
0
39
483
0.81
0.65
1.1
1.2
284.5
285.4
u/ml
0.01
21
297
182
1654
1.11
0.65
1.6
1.7
—
—
—
0
0
81
701
1.16
0.62
2.0
1.6
314.2
313.3
mu/l
0.01
74
642
106
936
1.14
0.62
1.2
1.2
—
—
—
0
0
97
852
1.14
0.61
1.2
1.2
—
—
—
0
0
54
452
1.20
0.61
1.2
1.1
—
—
—
0
0
5
30
1.67
0.61
1.0
1.0
—
—
—
0
0
21
156
1.35
0.61
1.2
1.1
—
—
—
0
0
2579
25438
1.04
0.60
19.8
18.4
13.7
13.8
%
1.93
2531
24834
17
122
1.40
0.60
2.6
1.9
18.5
19.9
ug/l
0.18
17
109
11
72
1.53
0.59
1.5
2.9
—
—
—
0
0
28
219
1.28
0.58
2.1
1.9
—
—
—
0
0
32
255
1.26
0.58
1.1
1.1
5.1
3.0
u/ml
0.20
12
101
266
2480
1.08
0.56
2.9
2.9
4.5
4.6
kpa
0.44
261
2395
20
150
1.34
0.55
1.1
1.6
—
—
—
0
0
120
1078
1.12
0.55
2.9
3.4
1.9
1.4
ratio
0.28
13
87
103
917
1.13
0.55
1.7
2.5
0.0
0.0
g/l
0.00
94
847
89
785
1.14
0.55
1.8
1.6
—
—
—
0
0
39
321
1.22
0.54
3.7
3.9
—
—
—
0
0
22
283
0.78
0.53
1.4
1.3
1.4
1.5
nmol/l
0.19
22
255
13
91
1.43
0.53
1.2
1.3
—
—
—
0
0
26
327
0.79
0.52
1.2
1.4
—
—
—
0
0
97
864
1.13
0.52
1.9
1.7
—
—
—
0
0
10
66
1.52
0.52
1.1
1.2
—
—
—
0
0
16
117
1.37
0.52
1.8
1.9
51.7
57.6
ug/l
0.26
16
112
6
98
0.61
0.52
2.0
2.7
—
—
—
0
0
6
98
0.61
0.52
2.0
2.7
—
—
—
0
0
9
65
1.39
0.50
1.8
1.5
—
—
—
0
0
44
519
0.85
0.49
1.1
1.2
—
—
—
0
0
98
880
1.12
0.48
1.2
1.4
—
—
—
0
0
164
1512
1.09
0.48
1.6
1.7
1.6
1.5
g/l
0.23
140
1295
102
920
1.11
0.46
1.6
1.5
—
—
—
0
0
27
218
1.24
0.46
1.1
1.1
—
—
—
0
0
25
309
0.81
0.45
1.4
1.4
—
—
—
0
0
11
77
1.43
0.45
1.0
1.1
—
—
—
0
0
22
174
1.27
0.44
1.1
1.2
1.0
1.0
ratio
—
7
58
25
308
0.81
0.44
1.4
1.4
—
—
—
0
0
25
307
0.81
0.43
1.4
1.4
—
—
—
0
0
25
307
0.81
0.43
1.4
1.4
—
—
—
0
0
11
78
1.41
0.43
1.2
1.1
—
—
—
0
0
5
31
1.61
0.43
1.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
2.6
0.6
0.8
u/field
—
5
34
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
18
0.00
0.40
0.0
1.3
—
4774.7
—
0
11
27
325
0.83
0.40
1.3
1.4
6.3
6.4
mmol/l
0.17
27
303
26
314
0.83
0.39
1.4
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
23.6
—
0
10
16
124
1.29
0.38
1.2
1.5
33.4
30.7
umol/l
0.50
16
119
27
224
1.21
0.38
1.1
1.0
290.0
291.3
mg/l
0.04
27
200
17
214
0.79
0.37
2.0
1.5
0.9
1.0
g/l
0.85
17
214
52
459
1.13
0.36
2.5
2.5
272.0
1801.0
u/ml
—
5
29
33
281
1.18
0.36
1.5
1.6
—
—
—
0
0
12
90
1.33
0.35
1.3
1.6
—
—
—
0
0
17
135
1.26
0.35
1.5
1.3
—
—
—
0
0
72
651
1.11
0.35
3.9
3.7
56.2
57.6
%
0.38
72
651
28
236
1.19
0.34
1.4
1.5
12.6
13.5
u/l
0.39
28
226
6
45
1.33
0.33
1.0
1.7
—
—
—
0
0
6
46
1.30
0.33
1.2
1.5
73.3
76.5
%
—
6
40
70
769
0.91
0.32
1.3
1.3
—
—
—
0
0
25
211
1.19
0.31
1.6
1.8
—
—
—
0
0
7
53
1.32
0.30
1.0
1.1
—
—
—
0
0
195
1851
1.06
0.30
1.7
1.8
—
—
—
0
0
139
1479
0.94
0.30
2.1
3.7
23.8
24.2
mmol/l
0.93
125
1318
14
111
1.26
0.30
1.5
1.7
—
—
—
0
0
326
3136
1.04
0.30
5.4
7.8
123.6
120.3
g/l
2.45
312
3021
274
2857
0.96
0.29
4.0
6.4
1.3
1.4
mmol/l
0.03
264
2755
87
804
1.08
0.29
1.5
1.6
8122.6
13932.6
e6/l
1.23
65
579
10
76
1.32
0.28
1.1
1.9
—
—
—
0
0
19
158
1.20
0.28
4.6
3.4
—
—
—
0
0
83
767
1.08
0.28
3.2
3.2
0.9
0.8
nmol/l
0.30
67
583
28
242
1.16
0.28
1.1
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
122
1145
1.07
0.28
2.6
3.0
0.4
0.4
u/ml
0.24
75
664
37
327
1.13
0.27
1.7
1.5
0.3
0.3
nmol/l
0.14
24
238
32
280
1.14
0.27
1.9
1.9
3.1
4.4
mg/l
2.17
32
271
9
117
0.77
0.27
1.0
1.0
—
—
—
0
0
26
224
1.16
0.27
1.3
1.6
5.1
6.5
u/l
—
9
112
46
414
1.11
0.26
1.3
1.5
2239.6
2094.2
e6/l
0.09
39
314
42
468
0.90
0.26
1.2
1.4
109.7
124.1
u/ml
—
10
95
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
19
160
1.19
0.25
1.1
1.1
—
—
—
0
0
9
75
1.20
0.25
3.2
1.5
—
—
—
0
0
9
77
1.17
0.24
1.0
1.3
—
—
—
0
0
9
77
1.17
0.24
1.1
1.1
—
—
—
0
0
6
82
0.73
0.24
1.0
1.1
—
—
—
0
0
41
454
0.90
0.24
1.2
1.2
1.3
3.9
u/ml
2.10
16
144
5
38
1.32
0.23
1.2
1.1
—
—
—
0
0
5
38
1.32
0.23
1.8
1.4
3.3
858071.9
nmol/l
—
5
31
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
13
106
1.23
0.23
1.2
1.4
3.7
3.1
mmol/l
0.42
13
96
183
1753
1.05
0.22
6.3
10.0
—
—
—
0
0
84
786
1.07
0.22
2.3
2.9
1.4
1.6
mg/l
2.32
76
709
165
1726
0.95
0.22
4.6
8.7
24.5
24.4
mmol/l
0.21
148
1601
297
2877
1.04
0.22
5.4
7.1
9.3
10.3
mmol/l
1.75
273
2738
0
10
0.00
0.21
0.0
1.8
—
1.7
—
0
10
23
201
1.15
0.21
1.2
1.2
—
—
—
0
0
23
201
1.15
0.21
1.5
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
2.4
—
0
14
56
520
1.08
0.19
1.3
1.4
—
—
—
0
0
49
453
1.08
0.18
1.3
1.4
—
—
—
0
0
14
164
0.85
0.18
1.1
1.1
—
—
—
0
0
76
717
1.06
0.17
2.6
3.2
1162.9
870.8
u/ml
0.10
68
657
42
387
1.09
0.17
1.7
1.6
—
—
—
0
0
24
214
1.12
0.17
1.7
1.6
—
—
—
0
0
45
417
1.08
0.16
1.2
1.1
12.2
13.1
au/ml
—
5
15
9
79
1.14
0.15
1.2
1.1
—
—
—
0
0
9
80
1.13
0.15
1.4
2.0
1.9
1.5
mmol/l
—
9
74
40
371
1.08
0.15
1.3
1.5
93553.0
73136.4
e6/l
0.15
27
226
46
430
1.07
0.14
1.1
1.1
—
—
—
0
0
11
93
1.18
0.14
1.4
1.5
8.3
8.9
ug/l
0.36
11
93
62
586
1.06
0.14
1.6
1.4
—
—
—
0
0
20
179
1.12
0.14
2.3
2.1
—
172.9
—
0
37
10
84
1.19
0.14
1.2
1.1
—
—
—
0
0
86
899
0.96
0.14
2.4
2.1
95.9
90.9
%
1.36
80
842
49
462
1.06
0.12
1.1
1.1
1.1
1368.5
iu/ml
—
9
96
41
436
0.94
0.12
1.1
1.1
—
—
—
0
0
31
288
1.08
0.11
1.4
2.1
4.8
2.0
u/field
0.55
12
104
79
823
0.96
0.11
1.7
1.5
—
—
—
0
0
34
318
1.07
0.11
1.3
1.4
29467.2
90636.2
e6/l
0.86
18
223
42
444
0.95
0.10
1.2
1.2
2.9
4.9
u/ml
1.38
22
182
13
115
1.13
0.10
1.2
1.5
2.2
2.1
umol/l
0.16
13
106
100
1033
0.97
0.10
1.3
1.4
—
—
—
0
0
58
606
0.96
0.10
1.6
1.8
1.1
0.8
nmol/l
0.60
45
497
5
45
1.11
0.09
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
82
847
0.97
0.09
2.5
2.5
3.7
3.6
g/l
0.21
77
796
72
696
1.04
0.08
1.3
1.3
—
—
—
0
0
72
696
1.04
0.08
1.3
1.3
—
—
—
0
0
5
60
0.83
0.08
1.4
1.4
—
—
—
0
0
11
98
1.12
0.07
1.0
1.1
1433.2
1658.2
miu/ml
0.24
11
98
19
176
1.08
0.07
1.6
1.7
2.9
4.7
ug/l
0.44
12
140
15
137
1.10
0.07
1.3
1.5
85.5
245.6
pmol/l
—
6
50
7
83
0.84
0.07
1.1
1.2
—
—
—
0
0
9
85
1.06
0.07
1.1
1.4
19.9
22.0
%
—
9
71
349
3451
1.01
0.07
3.4
3.6
—
—
—
0
0
9
88
1.02
0.07
1.0
1.1
—
—
—
0
0
9
88
1.02
0.07
1.0
1.1
—
—
—
0
0
49
472
1.04
0.06
1.8
1.4
—
—
—
0
0
8
92
0.87
0.06
1.0
1.1
—
—
—
0
0
8
92
0.87
0.06
1.0
1.1
—
—
—
0
0
79
770
1.03
0.06
1.9
1.7
—
—
—
0
0
288
2850
1.01
0.05
4.2
3.8
1.2
1.2
mmol/l
0.38
247
2470
16
171
0.94
0.05
1.5
1.4
—
—
—
0
0
16
171
0.94
0.05
1.5
1.4
—
—
—
0
0
23
242
0.95
0.05
2.7
1.6
—
—
—
0
0
30
312
0.96
0.04
1.3
1.4
29.5
29.5
%
0.00
15
191
17
160
1.06
0.04
1.0
1.2
—
—
—
0
0
21
200
1.05
0.03
1.5
1.6
—
—
—
0
0
16
151
1.06
0.03
3.3
2.6
617.8
1112.6
u/ml
1.58
16
151
12
112
1.07
0.03
2.4
1.3
—
—
—
0
0
316
3146
1.00
0.02
2.0
2.1
0.2
0.2
g/l
1.63
298
2931
127
1259
1.01
0.02
3.0
3.3
108.1
3535.1
u/ml
0.90
111
1056
28
272
1.03
0.02
1.0
1.0
—
—
—
0
0
413
4143
1.00
0.01
4.9
6.5
104.1
104.2
mmol/l
0.23
405
4048
29
297
0.98
0.01
1.0
1.1
—
—
—
0
0
98
988
0.99
0.01
1.9
1.7
—
—
—
0
0
47
464
1.01
0.00
1.8
1.5
—
—
—
0
0
21
208
1.01
0.00
1.1
1.4
1.3
1.2
promille
0.17
14
158
35
352
0.99
0.00
1.6
1.4
—
—
—
0
0
23
225
1.02
0.00
1.5
1.5
—
—
—
0
0
15
149
1.01
0.00
1.0
1.2
—
—
—
0
0
26
261
1.00
0.00
2.0
2.2
722.9
636.5
ml
0.30
17
169
82
824
1.00
0.00
3.0
2.4
183.0
195.9
%
0.68
75
782
65
654
0.99
0.00
2.3
2.7
35.7
35.4
umol/l
0.03
59
545
30
304
0.99
0.00
1.3
1.4
396.5
307.3
u/l
0.49
30
294
10
103
0.97
0.00
1.0
1.2
—
—
—
0
0
13
127
1.02
0.00
1.2
1.6
68.2
65.9
%
0.10
13
101
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
98
0.92
0.00
1.1
1.2
—
—
—
0
0
5
58
0.86
0.00
1.8
1.1
—
—
—
0
0
8
86
0.93
0.00
1.3
1.6
—
—
—
0
0
38
380
1.00
0.00
1.9
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
7.3
—
70.5
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
17
170
1.00
0.00
3.1
4.1
—
—
—
0
0
0
9
0.00
0.00
0.0
5.0
—
378.4
—
0
9
Mortality – FinRegistry
↥Association
Association between endpoint H8_MENIERE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MENIERE | 0.876 [0.8, 0.96] | 0.006 |
| Birth year | 0.991 [0.98, 1.0] | 0.033 |
During the follow-up period (1.1.1998 — 31.12.2019), 1902 out of 13148 females with H8_MENIERE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MENIERE | 0.777 [0.71, 0.85] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 1269 out of 7015 males with H8_MENIERE died.
Mortality risk
Mortality risk for people of age
years, who have H8_MENIERE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.092% | 0.158% |
| 5 | 0.431% | 0.937% |
| 10 | 1.069% | 2.318% |
| 15 | 2.118% | 4.412% |
| 20 | 3.919% | 7.457% |
Relationships between endpoints
↥Index endpoint: H8_MENIERE – Ménière disease
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data