Ménière disease

H8_MENIERE

endolymphatic hydrops: An accumulation of endolymph in the inner ear (labyrinth) leading to buildup of pressure and distortion of intralabyrinthine structures, such as cochlea and semicircular canals. It is characterized by sensorineural hearing loss; tinnitus; and sometimes vertigo.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H81.0
  • Hospital discharge: ICD-9 3860
  • Hospital discharge: ICD-8 38599
  • Cause of death: ICD-10 H81.0
  • Cause of death: ICD-9 3860
  • Cause of death: ICD-8 38599

2 out of 7 registries used, show all original rules.

3878

4. Check minimum number of events

None

3878

5. Include endpoints

None

3878

6. Filter based on genotype QC (FinnGen only)

3779

Control definitions (FinnGen only)

Control exclude
H8_INNER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H81
Name in latin
Morbus Ménière

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26706 17134 9455
Only index persons 24436 15945 8491
Unadjusted period prevalence (%)
Whole population 0.41 0.49 0.26
Only index persons 0.50 0.59 0.32
Median age at first event (years)
Whole population 57.15 57.45 56.61
Only index persons 56.64 56.87 56.19

-FinnGen-

Key figures

All Female Male
Number of individuals 3779 2467 1312
Unadjusted period prevalence (%) 0.78 0.88 0.60
Median age at first event (years) 55.74 54.61 57.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3878
Matched controls
38780
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H81.2
ICD-10 Finland
Vestibular neuronitis
96.9
321.3
167
18
Z01.1
ICD-10 Finland
Examination of ears and hearing
6.0
307.7
1380
3276
N07CA01
ATC
betahistine; oral
103.6
307.7
3001
1240
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
14.2
307.7
747
642
N05AB04
ATC
prochlorperazine; systemic, rectal
13.4
307.7
416
345
DFF59
NOMESCO Finland
Other assessment of balance
36.6
307.7
244
71
H81.0
ICD-10 Finland
Ménière disease
12235.0
307.7
3674
57
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
4.4
307.7
1393
4388
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
7.7
307.7
763
1199
H81.3
ICD-10 Finland
Other peripheral vertigo
45.5
307.7
504
127
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
4.0
307.7
1334
4482
R42
ICD-10 Finland
Dizziness and giddiness
7.3
307.7
2133
5554
DFF00
NOMESCO Finland
Pure tone audiometry
6.5
307.7
1070
2155
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
11.6
307.7
390
371
C03EA02
ATC
trichlormethiazide and potassium-sparing agents; oral
10.3
271.5
314
329
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
16.5
260.1
222
142
UDC00
NOMESCO Finland
Ear microscopy
4.9
249.7
619
1446
38599
ICD-8 Finland
Ménière's disease
+∞
221.0
210
*
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
22.6
198.8
146
67
DFF50
NOMESCO Finland
Electronystagmography
102.6
193.4
100
10
DFF15
NOMESCO Finland
Speech audiometry
5.0
193.0
449
987
3860A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Ménière's disease
+∞
177.5
169
*
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
13.6
171.4
162
124
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.8
147.4
496
1435
H93.1
ICD-10 Finland
Tinnitus
3.9
147.3
472
1320
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.3
137.5
383
965
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.1
130.8
394
1051
H02
ICPC
Hearing complaint
2.7
123.2
811
3462
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
31.4
118.2
77
25
N17
ICPC
Vertigo/dizziness
2.8
115.2
690
2798
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
105.5
1128
5955
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
87.2
474
1811
H82
ICPC
Vertiginous syndrome
6.2
86.6
150
249
DFE00
NOMESCO Finland
Insertion of cochlear implant
24.8
86.4
61
25
DC1AD
NOMESCO Finland
Temporalbone CT
9.3
85.3
103
113
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.9
81.8
248
660
DAX08
NOMESCO Finland
Fitting of hearing aid
3.1
73.8
329
1122
SPAT1043
SPAT
Audiometry
2.4
73.5
558
2503
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
69.9
599
2829
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
680.1
68.2
67
*
R5120
NOMESCO Finland
Preparation of an aid
3.9
65.9
202
541
H02AB06
ATC
prednisolone; systemic
1.8
63.9
1979
14391
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
6.1
63.9
112
188
H91.9
ICD-10 Finland
Hearing loss, unspecified
3.0
60.5
281
979
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
6.1
57.8
101
169
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
5.0
56.3
123
253
DFX00
NOMESCO Finland
Connecting cochlear implant
21.8
55.2
41
19
AA1AD
NOMESCO Finland
CT of head and brain
1.8
55.0
1169
7545
78050
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Vertigo
6.2
53.7
92
151
G44.2
ICD-10 Finland
Tension-type headache
2.1
53.1
583
3020
H29
ICPC
Ear symptom/complaint other
2.1
50.8
524
2648
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.4
50.4
185
559
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.8
46.1
85
150
R51.80
ICD-10 Finland
Headache
2.0
45.6
609
3369
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
44.6
923
5852
H81
ICD-10 Finland
Disorders of vestibular function
17.0
44.5
37
22
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
42.3
452
2306
H80.9
ICD-10 Finland
Otosclerosis, unspecified
148.3
41.8
44
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.2
41.8
170
547
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
13.6
41.7
39
29
H81.4
ICD-10 Finland
Vertigo of central origin
10.1
41.6
47
47
R06AE53
ATC
cyclizine, combinations; systemic
6.3
40.3
68
110
A02BC05
ATC
esomeprazole; systemic
1.6
40.1
1614
12056
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
40.0
347
1630
4173
FHL
Surgery on Saccus endolymphaticus
+∞
37.6
36
*
R01AD08
ATC
fluticasone; nasal
1.6
36.4
1064
7330
R01AD09
ATC
mometasone; nasal
1.5
36.3
1655
12625
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
35.3
1341
9806
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.7
33.2
76
163
DDA00
NOMESCO Finland
Stapedotomy
117.7
32.7
35
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
32.5
1099
7798
M03BX02
ATC
tizanidine; oral
1.5
32.4
2260
18679
H80.1
ICD-10 Finland
Otosclerosis involving oval window, obliterative
+∞
32.3
31
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
31.9
291
1392
H13
ICPC
Plugged feeling ear
1.7
31.1
762
4996
M25.5
ICD-10 Finland
Pain in joint
1.5
30.8
1178
8573
A02BC03
ATC
lansoprazole; oral
1.5
30.7
1141
8248
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
30.4
339
1749
R11
ICD-10 Finland
Nausea and vomiting
2.0
30.0
349
1828
A02BC02
ATC
pantoprazole; systemic
1.5
29.9
2612
22415
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.7
29.2
67
144
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
27.7
1129
8287
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
27.7
288
1447
M01AH05
ATC
etoricoxib; oral
1.5
27.6
2246
18848
H81.8
ICD-10 Finland
Other disorders of vestibular function
30.3
27.2
36
12
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
27.1
1128
8309
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
27.1
788
5366
M54.5
ICD-10 Finland
Low back pain
1.5
26.6
1282
9723
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
4.0
26.5
75
190
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
26.4
328
1755
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
26.1
1006
7283
N02BE01
ATC
paracetamol; systemic, rectal
1.7
25.9
3398
31253
UJF32
NOMESCO Finland
Coloscopy
1.5
25.7
1014
7375
Z97.8
ICD-10 Finland
Presence of other specified devices
6.9
25.4
39
57
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
25.4
1106
8202
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
25.3
398
2298
M79.6
ICD-10 Finland
Pain in limb
1.4
23.8
1520
12084
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
23.8
469
2888
R01AD58
ATC
fluticasone, combinations; nasal
1.5
23.7
786
5492
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
23.6
655
4398
N03AX12
ATC
[U] gabapentin; oral
1.6
23.3
627
4177
R03AC02
ATC
salbutamol; inhalant
1.4
23.1
1962
16359
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
22.8
1685
13708
H91.8
ICD-10 Finland
Other specified hearing loss
4.4
22.7
57
132
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
22.6
635
4272
Z01.2
ICD-10 Finland
Dental examination
1.4
22.3
1516
12143
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
22.2
722
5017
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
22.2
2469
21490
J01DB01
ATC
cefalexin; oral
1.5
22.1
3028
27364
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
22.0
1502
12035
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
21.9
1004
7480
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
21.7
798
5690
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
21.7
317
1788
XF404
NOMESCO Finland
Ambulatory ECG
1.8
21.4
341
1974
L01
ICPC
Neck symptom/complaint
1.6
21.3
547
3598
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
21.3
1887
15761
R53
ICD-10 Finland
Malaise and fatigue
1.5
21.0
848
6159
M01AE02
ATC
naproxen; oral, rectal
1.4
20.8
1976
16667
J01CA04
ATC
amoxicillin; systemic
1.4
20.5
2939
26530
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
20.5
649
4478
DFF16
NOMESCO Finland
Speech-in-noise audiometry
17.0
20.4
32
19
J01AA02
ATC
doxycycline; systemic
1.4
20.4
2908
26205
J01MA02
ATC
ciprofloxacin; systemic
1.4
20.2
1400
11198
SFA10
NOMESCO Finland
One-surface restoration
1.4
20.2
1837
15359
N06AX11
ATC
mirtazapine; oral
1.4
20.2
1218
9516
DFA00
NOMESCO Finland
Saccotomy
+∞
19.8
19
*
R06.0
ICD-10 Finland
Dyspnoea
1.4
19.6
992
7504
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.8
19.6
316
1835
A02BC01
ATC
omeprazole; systemic
1.4
19.5
1003
7608
H92.0
ICD-10 Finland
Otalgia
2.0
19.4
210
1071
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
19.3
422
2664
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.0
19.3
213
1094
R03BA05
ATC
fluticasone; inhalant
1.5
19.2
630
4372
A04AA01
ATC
ondansetron; systemic, rectal
1.8
18.9
310
1808
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
18.9
898
6711
3882A
ICD-9 Finland
Other disorders of ear, Sudden hearing loss, unspecified
15.9
18.8
30
19
C07AB07
ATC
bisoprolol; oral
1.4
18.7
1839
15496
SFA20
NOMESCO Finland
Two-surface restoration
1.4
18.5
1940
16493
M01AB05
ATC
diclofenac; systemic, rectal
1.4
18.4
2366
20745
SPAT1263
SPAT
Sampling
1.4
18.4
1469
11973
RK520, ,
NOMESCO Finland
6.9
18.2
28
41
N02AX02
ATC
tramadol; systemic, rectal
1.4
18.2
1541
12666
L03
ICPC
Low back symptom/complaint
1.4
18.1
953
7246
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
18.1
387
2429
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
17.8
2211
19234
R07.3
ICD-10 Finland
Other chest pain
1.7
17.7
372
2322
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
17.7
1767
14875
H02AB04
ATC
methylprednisolone; systemic
1.5
17.7
523
3545
J02AC01
ATC
fluconazole; systemic
1.4
17.7
1392
11302
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.9
17.6
82
287
3891A
ICD-9 Finland
Deafness, Sensorineural deafness
17.0
17.4
27
16
J01FA10
ATC
azithromycin; systemic
1.3
17.3
1927
16463
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.1
17.3
70
226
A02BC04
ATC
rabeprazole; oral
1.7
17.2
318
1918
TDA90
NOMESCO Finland
Removal wax from ear
3.3
17.2
64
196
N06AX21
ATC
duloxetine; oral
1.6
17.2
415
2684
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
17.1
547
3771
R05
ICD-10 Finland
Cough
1.4
17.0
751
5523
N03AX16
ATC
[U] pregabalin
1.4
17.0
839
6297
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
16.8
1677
14075
G43.9
ICD-10 Finland
Migraine, unspecified
2.0
16.7
177
895
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
16.7
516
3529
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
16.7
740
5444
K02.1
ICD-10 Finland
Caries of dentine
1.3
16.4
1904
16315
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
16.4
375
2391
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
16.4
700
5112
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
16.3
929
7137
J01FA06
ATC
roxithromycin; oral
1.3
16.3
1426
11727
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
16.2
290
1735
A98
ICPC
Health maint/preventive medicine
1.7
16.1
3627
34602
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
15.9
1549
12921
G47.3
ICD-10 Finland
Sleep apnoea
1.4
15.9
715
5266
N03AE01
ATC
clonazepam; systemic
1.9
15.7
211
1158
R01AD12
ATC
fluticasone furoate; nasal
1.4
15.7
987
7702
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
15.7
1466
12152
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
15.6
409
2693
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
15.6
1383
11375
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
15.6
390
2542
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
15.5
352
2240
J01DA01
ATC
[U] cefalexin
1.3
15.5
2197
19301
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
15.5
562
3973
N06AA09
ATC
amitriptyline; systemic
1.6
15.4
365
2347
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
15.4
859
6569
M01AX17
ATC
nimesulide; oral
1.4
15.2
884
6803
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
15.2
225
1272
SPAT1301
SPAT
No procedures
1.4
15.2
1102
8790
SPAT1260
SPAT
Consultation of another employee
1.5
15.1
617
4461
SPAT1153
SPAT
Removal of sutures
1.3
15.1
1141
9154
SPAT1312
SPAT
General health counselling
1.4
15.1
1054
8354
K30
ICD-10 Finland
Functional dyspepsia
1.6
15.0
388
2548
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
15.0
1815
15570
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
14.9
182
969
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.6
14.8
358
2313
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
14.8
261
1555
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
14.8
1425
11839
R55
ICD-10 Finland
Syncope and collapse
1.6
14.7
392
2590
R06AE07
ATC
cetirizine; oral
1.3
14.7
1501
12563
J35.0
ICD-10 Finland
Chronic tonsillitis
2.1
14.6
136
656
H83.1
ICD-10 Finland
Labyrinthine fistula
+∞
14.6
14
*
3861A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other and unspecified peripheral vertigo
+∞
14.6
14
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
14.6
353
2282
SPAT1097
SPAT
Recording of ECG
1.5
14.5
531
3758
R03DC03
ATC
montelukast; oral
1.5
14.4
555
3963
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
14.4
223
1278
A02BA02
ATC
ranitidine; systemic
1.4
14.4
702
5238
C07AA05
ATC
propranolol; systemic
1.4
14.4
661
4880
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
14.4
1307
10756
C10AA07
ATC
rosuvastatin; oral
1.3
14.4
1117
8986
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
14.2
1459
12208
XQ800
NOMESCO Finland
Prick test
1.8
14.2
232
1353
P01AB01
ATC
metronidazole; oral, rectal
1.3
14.1
1376
11427
S18
ICPC
Laceration/cut
1.3
14.1
1612
13685
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
14.0
881
6855
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
3.9
14.0
41
107
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
14.0
443
3040
J01FA09
ATC
clarithromycin; systemic
1.3
13.9
1037
8280
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
13.8
475
3317
R21
ICPC
Throat symptom/complaint
1.5
13.8
562
4057
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
13.7
1234
10125
H28
ICPC
Limited function/disability (H)
3.2
13.7
53
167
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
13.4
655
4886
DC1AI
NOMESCO Finland
Cone beam CT of ear
25.8
13.4
18
7
M79.1
ICD-10 Finland
Myalgia
1.5
13.3
465
3256
H66.9
ICD-10 Finland
Otitis media, unspecified
1.9
13.3
171
926
SGA01
NOMESCO Finland
Emergency treatment
1.5
13.2
464
3254
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
13.1
920
7269
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
12.9
219
1291
SFA30
NOMESCO Finland
Three-surface restoration
1.3
12.9
1383
11600
N05BB51
ATC
hydroxyzine, combinations; systemic
14.1
12.7
21
15
SPAT1310
SPAT
Counselling related to known health issue
1.3
12.7
1072
8697
N02BF01
ATC
gabapentin; oral
1.6
12.7
282
1785
UKC02
NOMESCO Finland
Cystoscopy
1.4
12.7
533
3867
H01
ICPC
Ear pain/earache
1.6
12.7
344
2283
R05
ICPC
Cough
1.4
12.6
797
6195
R01AD01
ATC
beclometasone; nasal
1.4
12.5
514
3715
R4110, ,
SPAT
1.6
12.5
304
1968
H61.2
ICD-10 Finland
Impacted cerumen
1.7
12.4
232
1403
J01EA01
ATC
trimethoprim; systemic
1.3
12.4
952
7614
H81
ICPC
Excessive ear wax
1.4
12.4
597
4436
R4135
NOMESCO Finland
Rehabilitation for hearing problems
2.5
12.3
75
302
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
12.2
2412
21787
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.8
12.1
188
1079
N06AB04
ATC
citalopram; systemic
1.4
12.1
714
5485
R06AX27
ATC
desloratadine; oral
1.3
12.0
876
6953
C03AA03
ATC
hydrochlorothiazide; oral
1.5
12.0
349
2352
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.6
11.9
272
1733
R50.9
ICD-10 Finland
Fever, unspecified
1.4
11.9
472
3385
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.6
11.8
322
2138
G04BD12
ATC
mirabegron; oral
1.5
11.7
427
3011
M01AG02
ATC
tolfenamic acid; oral, rectal
1.4
11.7
494
3583
R12
ICD-10 Finland
Heartburn
1.6
11.6
255
1608
XF402
NOMESCO Finland
ECG with work load test
1.5
11.6
369
2532
SPAT1325
SPAT
Vaccination
1.3
11.5
1166
9671
3870A
ICD-9 Finland
Otosclerosis involving oval window, nonobliterative
+∞
11.5
11
*
KMAK, ,
NOMESCO Finland
1.3
11.4
1644
14241
DE2CF
NOMESCO Finland
Acoustic channel extensive MRI examination with median intensity magnet
120.4
11.4
12
*
M48.0
ICD-10 Finland
Spinal stenosis
1.4
11.3
445
3184
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
4.2
11.3
29
69
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.5
11.3
377
2615
L08
ICPC
Shoulder symptom/complaint
1.3
11.2
738
5758
D82
ICPC
Teeth/gum disease
1.3
11.2
1107
9149
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
11.2
1420
12110
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
11.1
152
840
L17
ICPC
Foot/toe symptom/complaint
1.3
11.1
964
7825
M77.1
ICD-10 Finland
Lateral epicondylitis
1.7
11.1
219
1344
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
1.9
11.1
129
676
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.9
11.1
128
669
R74
ICPC
Upper respiratory infection acute
1.3
10.9
881
7079
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
10.9
224
1391
H60.3
ICD-10 Finland
Other infective otitis externa
2.3
10.9
83
371
R02
ICPC
Shortness of breath/dyspnoea
1.4
10.9
442
3183
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.7
10.8
205
1245
K07.60
ICD-10 Finland
Snapping jaw
1.8
10.8
157
885
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
10.8
790
6261
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
10.7
174
1013
A03CA02
ATC
clidinium and psycholeptics; oral
1.7
10.7
212
1304
K04.0
ICD-10 Finland
Pulpitis
1.6
10.7
247
1579
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
10.6
612
4677
M01AH02
ATC
rofecoxib; oral
1.4
10.6
454
3299
J01CA08
ATC
pivmecillinam; oral
1.3
10.6
1469
12634
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
10.6
398
2823
K07.61
ICD-10 Finland
Cracking jaw joint
2.6
10.6
60
234
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.6
10.5
221
1379
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.5
1503
12972
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.5
10.4
370
2595
34609
ICD-8 Finland
Migraine, Unspecified
3.5
10.4
35
101
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
10.4
719
5646
M01AH01
ATC
celecoxib; oral
1.4
10.4
623
4790
R03AC03
ATC
terbutaline; inhalant
1.4
10.3
461
3375
SPAT1041
SPAT
Comprehensive hearing test
2.7
10.3
53
197
M54.3
ICD-10 Finland
Sciatica
1.7
10.3
200
1225
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
3.4
10.3
36
107
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
10.2
188
1135
RK320, ,
NOMESCO Finland
3.5
10.2
34
98
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
10.1
650
5048
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.8
10.1
144
807
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
10.1
990
8156
P06
ICPC
Sleep disturbance
1.5
10.1
344
2396
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
10.0
680
5323
7840A
ICD-9 Finland
Symptoms involving head and neck, Headache
3.1
10.0
40
129
H53.2
ICD-10 Finland
Diplopia
2.0
10.0
112
581
L86
ICPC
Back syndrome with radiating pain
1.6
10.0
202
1250
H03
ICPC
Tinnitus, ringing/buzzing ear
2.3
10.0
75
334
UJF30
NOMESCO Finland
Ileoscopy through colon
1.5
9.9
336
2335
P01
ICPC
Feeling anxious/nervous/tense
1.5
9.9
271
1801
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
1.9
9.9
117
618
C10AA01
ATC
simvastatin; oral
1.2
9.9
1516
13161
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.9
9.8
115
605
L13
ICPC
Hip symptom/complaint
1.3
9.8
652
5087
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
9.8
930
7620
SPAT1216
SPAT
Assessment of functional ability
1.4
9.8
556
4234
B37.0
ICD-10 Finland
Candidal stomatitis
3.0
9.8
41
136
RK420, ,
NOMESCO Finland
10.6
9.8
18
17
G04CA02
ATC
tamsulosin; oral
1.3
9.8
657
5137
TAB00
NOMESCO Finland
Lumbar puncture
1.8
9.7
136
758
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
9.7
754
6015
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
9.7
761
6079
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
9.7
714
5654
C10AA05
ATC
atorvastatin; oral
1.2
9.7
1468
12718
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
2.6
9.7
56
221
H03AA01
ATC
levothyroxine sodium; systemic
1.3
9.7
830
6712
A01AB09
ATC
miconazole; local oral
1.5
9.7
294
1999
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.7
9.7
162
953
L02
ICPC
Back symptom/complaint
1.5
9.6
297
2025
C05AA08
ATC
fluocortolone; rectal, topical
1.4
9.6
452
3339
D33.30
ICD-10 Finland
Acoustic neuroma
3.7
9.6
29
78
R01AD59
ATC
mometasone, combinations; nasal
1.9
9.6
117
625
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
9.6
257
1702
C07AB02
ATC
metoprolol; systemic
1.3
9.5
703
5566
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.9
9.5
117
626
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
9.5
3212
30435
K80
ICPC
Cardiac arrhythmia NOS
1.5
9.5
272
1826
R83
ICPC
Respiratory infection other
1.3
9.5
672
5290
N05CF01
ATC
zopiclone; oral
1.3
9.5
1132
9536
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
2.4
9.5
65
278
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
9.5
447
3303
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
9.5
420
3071
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.6
9.4
240
1569
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
9.4
747
5973
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
9.4
421
3081
H83.8
ICD-10 Finland
Other specified diseases of inner ear
100.3
9.4
10
*
H80.8
ICD-10 Finland
Other otosclerosis
+∞
9.4
9
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.7
9.3
176
1069
N01
ICPC
Headache
1.5
9.3
280
1902
SPAT1104
SPAT
Monitoring of emergency patient
1.6
9.2
221
1425
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
9.2
1291
11070
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.0
9.2
90
445
R51
ICD-10 Finland
Headache
1.7
9.2
156
921
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
9.2
346
2456
A03FA02
ATC
cisapride; oral, rectal
1.5
9.2
263
1767
R06AX22
ATC
ebastine; oral
1.4
9.1
539
4129
L15
ICPC
Knee symptom/complaint
1.3
9.1
793
6419
R00.2
ICD-10 Finland
Palpitations
1.6
9.0
238
1569
R06AX13
ATC
loratadine; oral
1.4
9.0
450
3357
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
9.0
322
2264
XA402
NOMESCO Finland
ENMG
2.1
9.0
84
409
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
1.8
8.9
128
720
R03BC03
ATC
nedocromil; inhalant
1.6
8.9
226
1477
L12
ICPC
Hand/finger symptom/complaint
1.4
8.9
492
3729
R03BA02
ATC
budesonide; inhalant
1.3
8.9
572
4438
UDM02
NOMESCO Finland
Sinoscopy
2.2
8.9
74
344
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
8.9
640
5047
C01DA14
ATC
isosorbide mononitrate; oral
1.4
8.9
522
3996
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
8.9
279
1911
-1, ,
NOMESCO Finland
1.3
8.8
969
8070
M01AC06
ATC
meloxicam; systemic, rectal
1.2
8.8
1255
10775
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.5
8.7
241
1607
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
8.6
831
6808
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
8.6
320
2264
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
8.6
446
3345
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.6
8.6
213
1385
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.6
1354
11741
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.3
8.6
597
4684
K08.80
ICD-10 Finland
Toothache NOS
1.5
8.6
247
1661
A03
ICPC
Fever
1.4
8.6
440
3296
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
8.6
767
6227
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.8
8.6
113
620
N03AX11
ATC
topiramate; oral
2.2
8.6
71
330
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
16.3
8.5
13
8
H02AB07
ATC
prednisone; oral
1.4
8.5
454
3420
M02AA07
ATC
piroxicam; topical
1.2
8.5
1267
10913
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
8.5
611
4813
RK120, ,
NOMESCO Finland
6.9
8.5
20
29
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.3
8.5
827
6784
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.2
8.5
71
331
A04
ICPC
Weakness/tiredness general
1.4
8.5
469
3555
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
8.5
1253
10787
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.0
8.4
91
467
H80
ICD-10 Finland
Otosclerosis
90.3
8.4
9
*
M54.2
ICD-10 Finland
Cervicalgia
1.5
8.4
242
1629
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.4
8.3
322
2296
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.7
8.3
162
994
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
8.3
574
4499
G03DB01
ATC
dydrogesterone; oral
1.4
8.3
376
2760
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
2.9
8.3
37
128
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
8.3
518
4002
N06AB06
ATC
sertraline; oral
1.4
8.3
322
2300
R60.9
ICD-10 Finland
Oedema, unspecified
1.6
8.2
183
1160
N80.0
ICD-10 Finland
Endometriosis of uterus
2.2
8.2
63
284
C01CA24
ATC
epinephrine; parenteral
1.6
8.2
177
1115
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
8.2
829
6830
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
1.8
8.2
123
703
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
8.2
259
1778
N06AB10
ATC
escitalopram; oral
1.3
8.1
580
4564
H83.3
ICD-10 Finland
Noise effects on inner ear
4.4
8.1
20
46
J01DA09
ATC
[U] cefadroxil
1.3
8.1
826
6808
A01
ICPC
Pain general/multiple sites
1.5
8.1
296
2088
SPAT1229
SPAT
Assessment of need for aid
1.5
8.1
270
1873
Z45.3
ICD-10 Finland
Adjustment and management of implanted hearing device
17.2
8.1
12
7
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
8.1
1158
9926
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.3
8.0
702
5679
M01AC01
ATC
piroxicam; systemic, rectal
1.4
8.0
443
3361
RK110, ,
NOMESCO Finland
3.2
7.9
30
94
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.4
7.9
437
3312
N30.0
ICD-10 Finland
Acute cystitis
1.3
7.9
546
4279
Z71.8
ICD-10 Finland
Other specified counselling
1.3
7.8
938
7878
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
4.1
7.8
21
52
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
1.8
7.8
105
581
N06AX16
ATC
venlafaxine; oral
1.4
7.8
412
3102
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
7.7
399
2991
C01BC04
ATC
flecainide; systemic
1.8
7.7
114
648
4133
FHL
Stapedectomy sampling
45.1
7.7
9
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.5
7.7
220
1478
J01MA06
ATC
norfloxacin; oral
1.4
7.7
445
3396
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.7
7.7
124
724
K59.09
ICD-10 Finland
Constipation, unspecified
1.5
7.6
219
1472
R52.9
ICD-10 Finland
Pain, unspecified
1.4
7.6
296
2112
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.1
7.6
73
359
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
7.6
333
2427
N06AX26
ATC
vortioxetine; oral
1.6
7.6
183
1183
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
7.6
546
4302
J01FF01
ATC
clindamycin; systemic
1.3
7.6
862
7194
S06.0
ICD-10 Finland
Concussion
1.4
7.5
314
2271
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
7.5
942
7945
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.5
7.5
262
1833
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
3.0
7.5
32
108
SPAT1081
SPAT
Cardiorespiratory global assessment
1.6
7.5
182
1180
D02
ICPC
Abdominal pain epigastric
1.6
7.5
187
1220
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
7.5
635
5113
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
7.5
804
6664
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.3
7.4
801
6640
ZXA10
NOMESCO Finland
Bilateral
1.3
7.4
617
4953
N02CC03
ATC
zolmitriptan; nasal, oral
1.6
7.4
149
922
J05AB11
ATC
valaciclovir; oral
1.3
7.4
453
3484
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
2.0
7.4
74
371
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.7
7.3
115
666
38699, ,
ICD-8 Finland
+∞
7.3
7
*
M45
ICD-10 Finland
Ankylosing spondylitis
2.2
7.3
60
279
SPAT1351
SPAT
Extensive ear examination
3.1
7.3
29
94
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
2.4
7.3
47
197
SFA00
NOMESCO Finland
Small restoration
1.4
7.2
414
3153
PA6AD
NOMESCO Finland
CT of neck arteries
1.9
7.2
91
493
K39
ICPC
Cardiovascular, Physical function test
4.3
7.2
18
42
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
2.9
7.2
33
116
M79.7
ICD-10 Finland
Fibromyalgia
1.8
7.2
106
603
A02BA04
ATC
nizatidine; systemic
1.5
7.2
249
1740
D07AC01
ATC
betamethasone; topical
1.2
7.2
1176
10194
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.8
7.2
99
552
R04
ICPC
Breathing problem other
1.7
7.2
114
663
R03BA08
ATC
ciclesonide; inhalant
1.4
7.2
271
1926
M01AB08
ATC
etodolac; oral
1.5
7.2
234
1617
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.5
7.2
207
1395
N05BA04
ATC
oxazepam; oral
1.2
7.1
850
7124
J01FA01
ATC
erythromycin; systemic
1.4
7.1
379
2855
A02BX02
ATC
sucralfate; oral
1.7
7.1
132
801
M54.1
ICD-10 Finland
Radiculopathy
1.7
7.1
125
748
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
7.1
573
4583
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
1.8
7.1
97
540
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
7.0
596
4795
ZXC10
NOMESCO Finland
Use of laser
2.1
7.0
63
303
K04.1
ICD-10 Finland
Necrosis of pulp
1.4
7.0
300
2179
R06AE03
ATC
cyclizine; systemic, rectal
10.0
7.0
13
13
WZB00, ,
SPAT
1.5
7.0
192
1279
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
7.0
439
3391
207
Kela drug reimbursment
Chronic arrhythmias
1.3
7.0
532
4223
TDA90, ,
SPAT
1.6
7.0
158
1009
M22.4
ICD-10 Finland
Chondromalacia patellae
1.9
7.0
77
400
A06AC51
ATC
ispaghula, combinations; oral
1.6
6.9
150
948
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.5
6.9
210
1431
M54
ICD-10 Finland
Dorsalgia
1.4
6.8
352
2637
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
3.4
6.8
23
67
R30.0
ICD-10 Finland
Dysuria
1.7
6.8
123
741
R13
ICD-10 Finland
Dysphagia
1.5
6.8
220
1518
WX290
NOMESCO Finland
Other blockage of nerve
1.2
6.8
1324
11660
R06.5
ICD-10 Finland
Mouth breathing
1.4
6.8
246
1735
C03BB04
ATC
chlortalidone and potassium; oral
40.1
6.8
8
*
R35
ICD-10 Finland
Polyuria
1.5
6.7
202
1372
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.3
6.7
381
2898
M50.3
ICD-10 Finland
Other cervical disc degeneration
1.9
6.7
75
392
N03AF01
ATC
carbamazepine; oral, rectal
1.6
6.7
156
1004
M02AA10
ATC
ketoprofen; topical
1.3
6.6
520
4140
A11
ICPC
Chest pain NOS
1.4
6.6
257
1836
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.2
6.6
1208
10568
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.5
6.6
195
1323
N02CC07
ATC
frovatriptan; oral
1.8
6.5
97
554
K59.0
ICD-10 Finland
Constipation
1.5
6.5
169
1113
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
10.0
6.5
12
12
R31
ICD-10 Finland
Unspecified haematuria
1.4
6.5
295
2165
TEA00
NOMESCO Finland
Biopsy of lip
2.5
6.5
37
146
Z00.0
ICD-10 Finland
General medical examination
1.3
6.5
587
4758
D09
ICPC
Nausea
1.7
6.5
115
690
R07.0
ICD-10 Finland
Pain in throat
1.5
6.5
175
1163
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.5
2197
20299
C08CA05
ATC
nifedipine; systemic
1.5
6.5
190
1285
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.4
6.5
232
1633
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
1.7
6.5
110
653
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
1.8
6.5
88
490
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.1
6.4
58
280
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
1.9
6.4
73
383
XKD00
NOMESCO Finland
Uroflowmetry
1.3
6.4
432
3370
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.2
6.4
895
7620
L50.9
ICD-10 Finland
Urticaria, unspecified
1.7
6.4
102
595
H91.0
ICD-10 Finland
Ototoxic hearing loss
14.3
6.4
10
7
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.5
6.4
183
1232
N39.3
ICD-10 Finland
Stress incontinence
1.4
6.4
252
1806
L28
ICPC
Limited function/disability (L)
1.3
6.4
601
4897
SDA03
NOMESCO Finland
Periodontal treatment
1.2
6.4
1195
10473
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
6.4
547
4407
OAA65, ,
SPAT
1.4
6.3
326
2443
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
6.3
491
3905
D11
ICPC
Diarrhoea
1.4
6.3
318
2375
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
6.3
205
1417
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.4
6.3
282
2067
C10AA04
ATC
fluvastatin; oral
1.4
6.3
287
2110
D01
ICPC
Abdominal pain/cramps general
1.4
6.2
331
2495
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.6
6.2
129
808
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.5
6.2
200
1381
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.5
6.2
36
144
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.2
6.2
1070
9303
R52.2
ICD-10 Finland
Other chronic pain
1.7
6.1
112
678
PA7BD
NOMESCO Finland
CT angiography of neck and brain
2.1
6.1
53
252
E0000UV, ,
ATC
1.2
6.1
1335
11850
ZXA05
NOMESCO Finland
Left side
1.2
6.1
830
7041
G43
ICD-10 Finland
Migraine
1.7
6.1
103
611
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
2.5
6.1
36
145
R05FB02
ATC
cough suppressants and expectorants; systemic
1.2
6.1
1267
11200
J05AB01
ATC
aciclovir; systemic
1.2
6.1
687
5715
P25
ICPC
Phase of life problem adult
1.7
6.1
102
604
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
6.1
804
6804
C08DA01
ATC
verapamil; systemic
1.6
6.1
134
852
G50.1
ICD-10 Finland
Atypical facial pain
2.0
6.1
58
287
M01AX05
ATC
glucosamine; oral
1.2
6.1
703
5866
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
2.3
6.0
43
189
H57.1
ICD-10 Finland
Ocular pain
1.7
6.0
104
621
SPAT1240
SPAT
Therapeutic discussion
1.4
6.0
258
1877
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
3.2
6.0
23
73
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.4
6.0
285
2109

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2890
24202
1.76
49.64
4.8
4.1
11.71
13.22
mm/h
7.30
2703
22266
1418
10091
1.64
44.34
2.1
2.1
138.11
206.51
u/l
4.87
1317
9426
1661
12677
1.54
36.39
4.1
3.7
37.99
87.94
ng/l
0.78
1138
9002
2642
22487
1.55
33.63
5.1
4.5
—
—
—
0
0
1390
10371
1.53
32.83
2.4
2.5
56.98
66.62
u/l
0.64
1271
9547
3484
31991
1.88
30.56
16.6
15.0
21.80
24.18
mg/l
4.01
2863
25563
2310
19345
1.48
29.79
4.3
4.6
6.65
6.75
mmol/l
1.59
2199
18158
2900
25500
1.54
29.09
7.6
7.6
76.33
79.30
u/l
3.54
2707
23974
2540
21816
1.48
27.76
5.1
4.7
474.70
2383.54
e6/l
2.70
47
306
1922
15676
1.45
27.44
15.8
16.0
1.25
1.29
inr
0.78
540
4493
3574
33321
1.93
26.51
18.8
17.4
139.61
139.66
mmol/l
0.46
3506
32480
3270
29741
1.63
26.51
5.7
5.0
1.93
2.17
mu/l
1.48
3007
27055
3576
33405
1.91
25.48
19.0
17.5
3.95
3.97
mmol/l
7.08
3502
32512
3267
29822
1.61
24.76
6.2
5.9
39.69
40.08
mmol/mol
1.83
2981
27398
2820
25002
1.47
23.99
4.7
4.2
15.01
14.88
pmol/l
1.87
2558
22588
1869
15451
1.40
23.17
5.0
5.9
1.22
1.21
mmol/l
3.40
1687
14033
2064
17384
1.40
22.78
5.4
6.2
11.11
11.41
umol/l
0.65
1949
16499
3604
33967
1.86
21.81
11.8
10.8
24.93
25.18
u/l
0.46
3480
32671
360
2115
1.77
21.48
2.4
2.4
29.77
24.15
au/ml
0.27
23
139
2020
17066
1.38
21.24
5.9
6.6
1.22
1.22
mmol/l
3.88
1712
14447
3380
31355
1.61
21.12
5.2
4.7
5.93
5.97
mmol/l
1.02
3085
28390
3597
33944
1.82
20.77
19.3
17.6
77.10
76.90
umol/l
0.15
3597
33931
1255
9848
1.41
20.30
4.1
4.0
—
—
—
0
0
3446
32204
1.63
19.85
5.5
5.1
2.74
2.74
mmol/l
0.10
3158
29427
3358
31238
1.56
19.19
4.9
4.5
1.48
1.50
mmol/l
2.01
3063
28510
3380
31491
1.57
19.16
5.0
4.5
4.65
4.68
mmol/l
0.93
3104
28930
3514
33049
1.67
19.14
16.4
14.2
—
—
—
0
0
323
1911
1.75
18.76
1.3
1.3
70.47
49.91
au/ml
0.50
15
113
3682
35136
1.95
18.56
24.5
22.3
39.89
39.65
%
1.35
3415
32698
2313
20211
1.36
18.39
3.2
3.1
48.92
49.83
u/l
0.19
2140
18619
3255
30146
1.50
18.29
4.4
4.0
1.30
1.29
mmol/l
0.36
2937
27255
3682
35162
1.93
18.13
24.6
22.2
251.33
251.63
e9/l
0.10
3611
34208
3682
35170
1.93
17.99
24.5
22.1
91.07
91.31
fl
2.71
3636
34600
3682
35171
1.93
17.97
24.5
22.1
30.33
30.31
pg
0.23
3636
34598
3683
35184
1.93
17.97
24.8
22.3
134.71
133.51
g/l
6.04
3637
34621
3682
35174
1.93
17.92
24.6
22.2
4.47
4.43
e12/l
4.39
3599
34099
1253
10001
1.37
17.74
3.1
3.0
1279.51
1509.08
ng/l
0.65
1068
8605
3681
35173
1.92
17.73
24.7
22.2
6.72
6.73
e9/l
0.09
3598
34090
530
3609
1.54
17.55
2.2
2.1
107.52
136.35
ug/g
1.62
425
2813
695
5018
1.47
17.33
1.9
2.0
29.11
29.88
s
3.43
667
4866
1788
15124
1.34
17.13
6.6
6.3
—
—
—
0
0
1870
15934
1.34
16.99
4.1
3.9
0.00
0.00
estimate
0.13
348
3187
585
4107
1.50
16.73
4.9
4.6
33.08
33.09
%
0.00
420
2748
1943
16682
1.33
16.60
6.1
5.9
0.19
0.19
e9/l
0.12
1709
14550
1862
15916
1.33
16.28
5.5
5.2
0.00
0.00
estimate
0.80
327
2945
1877
16075
1.32
16.13
5.9
5.7
0.58
0.59
e9/l
0.82
1638
13809
882
6729
1.40
16.13
1.3
1.2
1.27
1.60
u/ml
0.50
215
1747
1917
16483
1.32
15.95
5.9
5.8
1.94
1.91
e9/l
0.31
1711
14492
1878
16117
1.32
15.76
5.9
5.7
0.04
0.04
e9/l
0.00
1634
13842
914
7046
1.39
15.65
1.9
1.7
1.18
1.26
mg/l
0.23
691
5430
1875
16106
1.32
15.55
4.2
3.9
0.02
0.00
estimate
0.63
326
2896
631
4566
1.46
15.40
1.2
1.2
—
—
—
0
0
739
5513
1.42
15.27
1.3
1.3
28.19
33.14
iu/ml
0.74
218
1766
1522
12749
1.32
14.91
3.8
3.6
5.93
5.84
ph
0.51
97
757
588
4222
1.46
14.90
1.4
1.3
615.89
523.73
titre
0.52
141
943
706
5247
1.42
14.86
1.3
1.2
10.76
12.36
u/ml
0.26
256
1969
369
2418
1.58
14.37
1.1
1.2
—
—
—
0
0
1064
8526
1.34
13.98
2.6
2.7
3823.20
5392.17
umol/l
0.69
929
7377
1761
15160
1.30
13.70
6.8
6.3
8.48
8.67
%
1.86
1641
14120
1795
15501
1.29
13.60
6.5
6.1
28.09
27.50
%
1.41
1677
14472
1751
15080
1.29
13.51
6.4
6.0
2.83
2.83
%
0.05
1633
14019
1710
14683
1.29
13.50
4.2
4.7
35.85
35.18
g/l
6.02
1580
13614
1770
15270
1.29
13.46
6.2
5.9
57.02
57.53
%
0.99
1651
14236
833
6486
1.36
13.08
4.1
3.7
214.33
382.37
ng/l
1.32
650
5214
2123
18828
1.28
12.67
8.5
9.1
4.11
4.11
e9/l
0.03
1859
16403
480
3441
1.45
12.13
4.1
4.3
—
—
—
0
0
1630
14041
1.28
12.08
2.1
2.0
98.53
95.49
pmol/l
1.50
805
7056
752
5843
1.36
11.84
1.5
1.5
2.33
2.49
g/l
1.41
427
3450
1686
14648
1.27
11.44
6.4
6.0
0.70
0.68
%
1.05
1568
13586
1565
13553
1.26
10.67
2.2
2.1
—
—
—
0
0
1563
13548
1.26
10.53
2.9
2.8
124.83
128.39
ug/l
0.16
1429
12446
1292
10955
1.27
10.48
3.3
3.3
—
—
—
0
0
1367
11704
1.26
10.13
3.0
3.4
2.35
2.36
mmol/l
0.23
1155
10217
862
6973
1.30
10.07
4.6
4.4
1.01
1.02
kg/l
1.59
151
1052
319
2191
1.50
9.99
2.6
3.2
4.58
5.17
e9/l
0.28
245
1735
407
2948
1.43
9.67
2.1
2.2
374.26
374.05
nmol/l
0.01
371
2691
332
2319
1.47
9.56
1.4
1.4
—
—
—
0
0
150
887
1.72
8.81
1.3
1.2
15.23
44.56
u/ml
1.27
12
55
83
406
2.07
8.76
1.3
1.2
—
—
—
0
0
1585
13957
1.23
8.72
2.4
2.2
80.05
79.17
nmol/l
0.59
1422
12424
245
1672
1.50
7.94
2.5
2.7
0.13
0.30
e6/l
3.41
236
1625
266
1846
1.47
7.94
1.3
1.3
252.20
195.93
u/ml
0.30
253
1686
991
8383
1.24
7.73
3.8
3.5
—
—
—
0
0
1005
8530
1.24
7.58
2.4
2.2
2.93
3.05
mg/l
1.02
872
7218
326
2376
1.41
7.48
3.0
2.7
10.00
10.55
g/l
1.68
300
2164
801
6643
1.26
7.40
1.7
1.8
1126.07
1180.78
nmol/l
0.99
622
4993
81
420
1.95
7.33
2.6
2.2
25.22
24.10
mg/l
0.06
27
103
467
3629
1.33
7.13
1.3
1.3
—
—
—
0
0
134
819
1.66
7.03
1.3
1.2
2.21
6.28
u/ml
0.62
12
92
1323
11633
1.21
6.93
3.7
3.7
82.71
118.19
e6/l
1.14
956
8267
135
831
1.65
6.90
1.3
1.2
6.69
7.67
u/ml
0.07
20
143
1181
10280
1.21
6.86
3.7
4.0
7.40
7.40
ph
0.66
197
1952
186
1240
1.53
6.78
1.3
1.2
1.26
1.50
u/ml
0.08
22
109
986
8442
1.23
6.73
5.5
5.1
3.80
3.59
ug/l
0.08
896
7511
1004
8614
1.22
6.71
4.7
4.3
0.01
0.00
estimate
0.26
321
2858
2477
23108
1.20
6.65
4.2
3.9
—
—
—
0
0
477
3764
1.30
6.51
2.4
2.6
9.35
8.38
umol/l
0.31
419
3258
130
806
1.63
6.48
1.1
1.1
5.60
6.57
u/ml
—
5
86
46
205
2.26
6.23
1.0
1.1
269.11
278.83
mg/l
0.14
41
175
79
431
1.85
6.20
1.3
1.3
—
—
—
0
0
84
469
1.81
6.12
1.4
1.3
0.16
0.36
nmol/l
—
5
31
1139
9989
1.20
5.94
3.2
3.2
62.70
79.38
e6/l
0.46
878
7673
74
402
1.86
5.90
1.4
1.3
—
—
nmol/l
—
0
0
46
212
2.18
5.78
1.1
1.1
34.80
40.74
mg/l
0.56
41
178
272
2019
1.37
5.64
3.2
3.7
7.42
7.41
ph
0.81
41
269
295
2222
1.35
5.57
1.2
1.2
—
—
—
0
0
411
3254
1.29
5.47
1.6
1.6
—
—
—
0
0
368
2875
1.31
5.41
2.7
2.7
66.16
66.42
g/l
0.29
337
2619
40
181
2.22
5.28
1.2
1.6
5.11
7.31
u/l
1.28
34
156
251
1862
1.37
5.24
2.5
2.4
—
—
—
0
0
204
1462
1.42
5.22
1.3
1.2
—
—
—
0
0
272
2045
1.35
5.21
3.2
3.7
5.12
5.18
kpa
0.58
256
1942
916
7957
1.20
5.20
1.5
1.6
20.70
20.68
nmol/l
0.01
776
6758
67
369
1.83
5.16
4.0
4.1
—
—
—
0
0
54
278
1.96
5.10
1.3
1.2
—
50.00
—
0
13
1168
10378
1.18
5.10
3.1
3.2
30.16
36.64
u/l
2.86
1095
9811
43
205
2.11
5.01
1.8
1.7
17.24
16.95
nmol/l
0.10
43
188
1680
15381
1.16
5.00
2.5
2.6
—
—
—
0
0
176
1238
1.44
5.00
3.7
3.9
25.00
24.94
mmol/l
0.11
162
1136
155
1070
1.47
4.87
4.9
6.8
1.37
1.32
mmol/l
0.24
138
945
378
3013
1.28
4.79
3.1
2.9
210.08
211.50
ng/l
0.02
354
2748
11
17
6.49
4.77
1.8
1.4
15.75
35.95
pmol/l
0.48
11
12
308
2393
1.31
4.74
2.6
2.5
—
—
—
0
0
263
1998
1.34
4.73
3.3
3.3
4.38
4.43
pmol/l
0.37
233
1760
341
2690
1.29
4.69
3.0
3.6
76.85
90.33
ng/l
2.98
289
2294
1111
9891
1.17
4.66
3.3
3.2
493.36
359.18
mg/l
0.35
649
6184
808
7010
1.19
4.60
2.5
2.6
4.43
5.86
e6/l
3.88
710
6296
1164
10424
1.17
4.51
3.8
3.8
7.12
8.56
mg/mmol
0.53
661
6450
134
914
1.48
4.50
2.1
1.6
0.23
0.24
g/l
0.28
129
869
37
175
2.13
4.43
1.1
1.1
0.31
6.58
nmol/l
—
7
39
354
2839
1.27
4.28
3.9
3.6
—
—
—
0
0
64
370
1.74
4.26
1.5
1.4
31.30
32.93
u/l
0.13
51
307
136
943
1.46
4.22
2.0
1.6
1.17
1.18
g/l
0.14
131
899
35
166
2.12
4.18
1.2
1.5
5.89
8.84
ug/l
1.60
30
143
1139
10242
1.16
4.12
3.2
3.1
7.09
7.07
mmol/l
0.05
953
8599
194
1447
1.36
3.98
3.4
3.8
—
—
—
0
0
288
2273
1.29
3.98
4.2
4.9
—
—
—
0
0
97
637
1.54
3.94
1.3
1.2
52.55
45.10
u/ml
0.11
11
70
358
2912
1.25
3.86
1.5
1.5
—
—
—
0
0
34
165
2.07
3.85
1.4
1.5
—
—
—
0
0
0
101
0.00
3.81
0.0
2.3
—
149.39
—
0
87
635
5480
1.19
3.80
3.1
3.2
0.82
0.82
mmol/l
0.71
572
5110
65
391
1.67
3.79
1.3
1.3
88.72
55.83
u/ml
—
8
23
2849
27366
1.15
3.78
18.8
17.9
15.73
15.14
%
4.27
2811
26842
168
1236
1.38
3.78
2.7
2.6
—
—
—
0
0
87
564
1.56
3.76
1.5
1.6
—
—
—
0
0
1027
9223
1.15
3.72
3.1
3.1
0.37
0.47
e6/l
0.77
787
7056
155
1131
1.39
3.67
1.6
1.6
—
—
—
0
0
360
2960
1.24
3.54
2.5
2.3
6.75
6.75
ug/l
0.00
308
2580
902
8051
1.16
3.54
2.3
2.3
—
—
—
0
0
835
7414
1.16
3.51
1.6
1.7
544.34
31358866.78
pmol/l
5.66
693
6110
138
1003
1.39
3.37
1.4
1.4
286.89
277.10
ug/g
0.21
83
579
75
483
1.56
3.37
1.8
1.6
0.68
0.81
g/l
0.70
56
360
862
7695
1.15
3.36
4.1
3.8
—
—
—
0
0
607
5282
1.18
3.29
2.3
2.5
13.33
12.76
umol/l
1.13
561
4904
18
71
2.54
3.29
1.9
2.0
—
—
—
0
0
89
599
1.50
3.28
2.0
1.8
5939.94
3366.19
u/l
0.25
26
237
1157
10554
1.14
3.28
2.4
2.4
—
—
—
0
0
96
658
1.47
3.24
1.2
1.4
12.75
31.53
e6/l
1.06
83
500
255
2038
1.27
3.23
1.2
1.2
109.39
152.73
iu/ml
1.26
104
746
446
3787
1.20
3.20
1.5
1.4
—
—
—
0
0
57
348
1.65
3.20
2.3
2.0
—
—
—
0
0
184
1411
1.32
3.20
4.7
5.6
1.57
1.61
%
0.21
172
1319
96
660
1.47
3.20
1.3
1.4
1492.55
1433.48
e6/l
0.02
84
534
310
2539
1.24
3.18
3.4
3.9
0.50
0.70
%
1.32
110
831
87
588
1.49
3.16
1.5
1.3
11.79
12.72
u/l
0.28
75
470
988
8957
1.14
3.05
3.1
3.1
—
—
—
0
0
67
432
1.56
3.03
1.3
1.4
70.66
44.01
mu/l
0.83
61
385
107
760
1.42
3.02
6.0
7.9
105.12
105.02
mmol/l
0.09
98
679
107
760
1.42
3.02
6.0
7.9
11.08
11.14
mmol/l
0.07
98
679
736
6554
1.15
2.95
2.9
3.1
2.45
2.46
mmol/l
0.89
620
5730
319
2646
1.22
2.93
3.7
4.1
0.09
0.11
%
0.23
108
832
41
235
1.75
2.92
2.2
1.7
—
—
—
0
0
19
83
2.30
2.83
1.2
1.1
248.43
316.87
pmol/l
0.59
14
63
234
1884
1.26
2.82
2.0
1.9
1.11
1.43
g/l
2.43
210
1711
750
6708
1.15
2.82
3.0
2.9
523.71
532.00
mosm/kgh2o
0.42
627
5771
264
2160
1.24
2.77
6.1
7.0
24.88
24.63
mmol/l
0.61
249
2056
332
2782
1.21
2.76
3.7
4.1
0.82
0.89
%
0.22
123
965
103
741
1.40
2.74
2.1
2.3
138.71
127.36
g/l
4.54
73
539
218
1751
1.26
2.70
1.3
1.2
—
—
—
0
0
175
1371
1.29
2.65
1.9
2.0
2.43
2.40
ug/l
0.01
144
1209
117
865
1.36
2.65
1.1
1.1
—
—
—
0
0
954
8704
1.13
2.62
1.8
1.6
1.36
1.36
mmol/l
0.02
799
7245
178
1401
1.28
2.61
4.8
5.6
0.95
0.89
%
1.22
167
1311
85
597
1.43
2.60
1.1
1.3
—
—
—
0
0
17
74
2.30
2.57
1.0
1.1
0.88
0.70
umol/24h
—
7
37
1006
9219
1.12
2.56
4.1
4.3
—
—
—
0
0
174
1370
1.28
2.55
1.1
1.1
52.00
174.74
titre
—
5
35
438
3802
1.17
2.47
1.7
1.8
—
—
—
0
0
148
1148
1.30
2.45
1.4
1.3
29.90
33.57
iu/l
0.71
126
985
338
2875
1.19
2.43
2.5
2.5
69.12
70.19
e9/l
0.21
276
2154
439
3819
1.17
2.41
2.5
2.5
1.78
1.81
%
0.19
394
3369
204
1651
1.25
2.40
2.2
2.2
11.77
12.10
nmol/l
0.22
183
1452
267
2226
1.21
2.38
3.5
3.2
—
—
—
0
0
111
832
1.34
2.34
1.8
2.0
13.48
11.65
mg/l
0.18
102
763
494
4350
1.16
2.32
4.2
5.5
1.01
1.04
mmol/l
1.95
454
4015
632
5664
1.14
2.30
2.8
2.7
1.15
1.21
e6/l
0.15
392
3253
6
13
4.62
2.27
1.5
1.8
213.67
216.31
ng/l
—
6
13
169
1355
1.26
2.18
1.7
2.5
7.47
7.46
g/l
0.01
152
1224
2722
26404
1.10
2.12
21.3
19.6
332.42
331.41
g/l
7.57
2709
26186
168
1353
1.25
2.10
1.7
2.5
3.72
3.65
g/l
0.25
151
1223
19
95
2.00
2.10
2.1
1.7
—
—
—
0
0
5
10
5.00
2.07
1.0
1.1
5.68
4.56
mmol/l
—
5
5
201
1663
1.22
1.98
3.3
3.1
25.61
25.35
mmol/l
0.51
195
1610
157
1268
1.25
1.94
1.7
2.5
2.84
2.98
g/l
1.05
140
1137
37
236
1.57
1.87
1.2
1.2
—
—
—
0
0
15
291
0.51
1.86
1.3
1.5
—
—
—
0
0
82
612
1.35
1.85
1.9
1.9
5.72
4.83
mmol/24h
1.09
72
522
32
198
1.62
1.83
1.7
1.6
—
—
—
0
0
117
921
1.28
1.81
1.0
1.1
—
—
—
0
0
422
3747
1.14
1.80
3.4
4.0
11.94
26.47
ug/l
1.17
340
3047
15
284
0.53
1.74
1.3
1.4
—
—
—
0
0
9
36
2.50
1.74
1.6
1.8
2.69
2.90
mmol/l
—
9
29
13
61
2.13
1.71
1.0
1.1
3.25
12.23
u/ml
—
5
35
96
743
1.30
1.71
1.8
1.6
—
—
—
0
0
15
282
0.53
1.70
1.3
1.4
—
—
—
0
0
577
5245
1.12
1.69
3.0
2.9
3.59
2.91
e6/l
0.63
341
2853
30
187
1.61
1.68
1.1
1.0
—
—
—
0
0
45
308
1.47
1.68
1.5
1.4
6.77
7.10
g/l
0.29
31
214
45
308
1.47
1.68
1.5
1.4
2.49
2.88
g/l
0.85
31
215
45
308
1.47
1.68
1.5
1.4
0.39
0.40
g/l
0.11
33
215
72
536
1.35
1.68
1.4
1.4
—
—
—
0
0
49
342
1.44
1.66
3.4
3.4
51.99
56.92
%
0.83
41
289
537
4868
1.12
1.65
2.2
2.4
2.40
2.32
g/l
2.84
490
4489
14
69
2.03
1.64
1.1
1.1
0.02
2.10
u/ml
—
9
30
239
2052
1.18
1.62
3.1
3.0
128.66
127.61
g/l
0.34
232
1998
31
197
1.58
1.62
1.1
1.1
—
—
—
0
0
287
2501
1.16
1.61
3.7
4.1
0.59
0.42
%
0.10
78
692
12
56
2.15
1.61
1.2
1.4
84.34
103.65
ng/l
0.40
12
56
103
816
1.27
1.55
1.9
1.8
3.46
4.57
iu/l
1.42
36
278
7
27
2.60
1.51
1.0
1.2
—
—
—
0
0
502
4561
1.12
1.50
2.3
2.5
22.42
22.35
%
0.03
402
3871
139
1145
1.22
1.50
3.2
3.0
0.26
0.27
g/l
0.07
50
437
25
154
1.63
1.49
1.2
1.1
—
—
—
0
0
27
171
1.58
1.45
1.3
1.7
3.94
1.94
u/field
0.58
18
119
180
1526
1.19
1.44
1.9
2.0
—
—
—
0
0
17
95
1.79
1.43
1.2
1.2
36.25
38.54
g/l
—
10
50
34
229
1.49
1.41
1.0
1.0
292.50
327.86
ng/l
0.36
26
145
34
229
1.49
1.41
1.0
1.0
719.79
712.49
ng/l
0.03
24
142
536
4912
1.11
1.37
3.1
3.1
0.80
0.78
ug/l
0.12
354
3358
124
1493
0.82
1.33
1.5
1.5
—
—
—
0
0
11
54
2.04
1.32
1.2
1.0
—
—
—
0
0
43
309
1.40
1.30
1.5
1.4
—
—
—
0
0
150
1266
1.19
1.29
1.8
2.5
9.88
10.31
g/l
0.75
132
1126
5
18
2.78
1.28
2.2
1.5
347.80
332.83
umol/24h
—
5
18
9
175
0.51
1.28
1.7
2.1
—
—
—
0
0
22
138
1.60
1.26
1.2
1.3
139.82
149.67
mmol/24h
0.27
22
138
46
337
1.37
1.25
2.5
1.4
26.20
21.33
iu/ml
—
5
15
31
211
1.47
1.25
1.5
1.3
33.33
73.16
titre
—
6
19
78
617
1.27
1.25
2.2
2.9
—
—
—
0
0
8
36
2.22
1.24
2.0
2.6
—
33.44
—
0
5
50
372
1.35
1.24
2.3
2.0
—
—
—
0
0
11
56
1.97
1.22
5.1
2.8
—
—
—
0
0
8
37
2.16
1.21
1.0
1.2
1.49
1.75
umol/24h
—
8
37
19
116
1.64
1.21
2.9
2.4
270.25
151.11
umol/l
—
8
63
34
238
1.43
1.20
1.1
1.1
—
—
—
0
0
89
720
1.24
1.19
2.7
2.6
18.30
15.92
%
5.20
51
372
15
86
1.75
1.18
1.1
1.0
—
—
—
0
0
66
515
1.29
1.18
2.3
2.6
—
—
—
0
0
9
168
0.53
1.18
1.8
2.3
—
—
—
0
0
505
4654
1.10
1.18
1.8
2.0
—
—
—
0
0
428
3914
1.11
1.17
4.7
7.0
12.34
12.21
kpa
0.18
402
3728
12
211
0.57
1.16
1.0
1.1
—
—
—
0
0
49
368
1.34
1.16
2.7
2.7
—
—
—
0
0
0
34
0.00
1.16
0.0
1.3
—
—
—
0
0
0
34
0.00
1.16
0.0
1.2
—
—
—
0
0
5
20
2.50
1.15
1.4
1.1
—
—
—
0
0
5
20
2.50
1.15
1.0
1.4
—
—
—
0
0
427
3916
1.10
1.11
4.7
7.0
5.05
5.10
kpa
0.52
402
3731
426
3908
1.10
1.10
4.7
7.0
1.34
1.19
mmol/l
0.34
333
3093
163
1409
1.16
1.10
4.5
4.2
—
—
—
0
0
29
202
1.44
1.07
1.0
1.1
—
—
—
0
0
338
3070
1.11
1.07
2.9
3.5
1.80
2.03
mmol/l
0.63
300
2595
128
1088
1.18
1.06
1.1
1.1
—
—
—
0
0
17
105
1.62
1.06
1.5
1.2
—
—
—
0
0
24
162
1.48
1.04
1.0
1.0
—
—
—
0
0
18
114
1.58
1.02
1.2
1.1
1610.38
436.68
ng/l
—
5
28
55
430
1.28
1.01
2.7
2.4
—
—
—
0
0
93
773
1.21
1.00
1.2
1.2
—
—
—
0
0
47
361
1.31
0.99
1.2
1.3
7.73
7.59
mmol/l
0.11
40
307
7
133
0.53
0.98
2.0
1.4
—
—
—
0
0
473
4388
1.09
0.98
1.3
1.3
—
—
—
0
0
131
1127
1.17
0.97
2.9
3.4
34.32
106.32
mg/l
0.83
111
926
131
1127
1.17
0.97
2.9
3.4
45.15
62.93
mg/l
0.45
110
924
29
208
1.40
0.94
2.9
3.7
—
—
—
0
0
123
1056
1.17
0.94
1.6
2.4
38.06
37.64
g/l
0.32
106
924
8
145
0.55
0.92
7.6
11.5
0.57
0.63
mmol/l
—
8
131
337
3088
1.10
0.92
2.9
3.5
5.74
5.86
kpa
1.43
331
2992
40
304
1.32
0.92
1.1
1.4
—
—
—
0
0
85
708
1.21
0.91
3.8
3.5
28.67
28.15
mg/l
0.04
53
435
33
441
0.75
0.91
3.5
5.0
372.34
356.14
umol/l
0.25
25
383
50
393
1.28
0.90
1.4
1.5
—
—
—
0
0
25
176
1.42
0.90
2.2
1.6
—
—
—
0
0
22
151
1.46
0.90
4.4
4.0
—
—
—
0
0
41
314
1.31
0.90
3.9
5.0
15.35
77.87
u/ml
1.84
11
88
48
376
1.28
0.89
1.0
1.1
5.39
3.52
u/ml
0.41
21
178
82
684
1.20
0.88
1.2
1.3
161.94
212.60
miu/ml
0.79
33
299
239
2159
1.11
0.87
1.4
1.4
—
—
—
0
0
237
2140
1.11
0.87
1.4
1.3
—
—
—
0
0
31
415
0.74
0.87
1.1
1.2
—
—
—
0
0
101
860
1.18
0.87
1.2
1.2
124.00
85.00
titre
—
10
66
23
161
1.43
0.86
1.2
1.3
135.13
134.68
nmol/l
0.01
23
161
29
212
1.37
0.86
1.3
1.3
0.09
1.04
u/ml
1.58
17
122
91
769
1.19
0.85
3.3
4.5
2.20
2.71
mmol/l
1.32
53
533
18
120
1.50
0.85
5.8
6.2
70.78
62.39
mg/l
—
9
87
12
72
1.67
0.85
1.1
1.3
2.50
1.62
mmol/l
—
6
48
6
31
1.94
0.84
1.2
1.2
—
—
—
0
0
6
31
1.94
0.84
1.2
1.0
—
—
—
0
0
6
31
1.94
0.84
1.2
1.2
—
—
—
0
0
6
31
1.94
0.84
3.0
3.0
—
—
—
0
0
78
651
1.20
0.84
1.2
1.3
65.03
61.30
mmol/l
0.36
59
527
878
8383
1.06
0.84
5.9
6.8
—
—
—
0
0
66
542
1.22
0.84
1.3
1.2
35.25
35.05
u/l
0.00
59
466
40
310
1.29
0.82
1.1
1.2
—
—
—
0
0
22
155
1.42
0.81
1.3
1.4
17.49
22.59
umol/l
0.44
22
146
54
436
1.24
0.80
1.1
1.1
1.82
2.06
u/ml
0.06
28
228
67
806
0.83
0.80
2.2
2.2
80.07
98.81
ug/min
0.18
44
478
30
224
1.34
0.79
1.2
1.8
16.38
9.17
umol/l
0.22
19
158
337
3116
1.09
0.79
2.3
2.3
33.41
39.41
u/l
0.98
287
2650
217
1964
1.11
0.79
1.3
1.4
—
—
—
0
0
45
357
1.26
0.78
1.6
1.2
—
—
—
0
0
14
90
1.56
0.78
1.4
1.3
36.25
33.42
%
—
8
57
1474
14303
1.05
0.77
10.2
9.8
0.00
0.00
e9/l
1.19
1241
11655
37
287
1.29
0.77
1.1
1.1
5.41
2.63
u/ml
0.27
18
130
67
558
1.20
0.76
4.0
3.6
1.21
1.58
%
0.53
58
496
876
8392
1.06
0.75
3.8
3.8
90.51
89.73
%
0.41
855
8165
275
2528
1.09
0.74
3.0
2.8
4.47
4.55
kpa
0.31
270
2441
128
1127
1.14
0.74
1.8
2.2
232.54
685.07
ug/l
1.66
116
1055
117
1025
1.15
0.73
2.6
3.5
—
—
—
0
0
60
497
1.21
0.72
1.1
1.1
—
—
—
0
0
129
1139
1.14
0.72
2.0
1.9
21.04
21.46
s
0.41
111
988
13
84
1.55
0.71
1.8
1.8
—
—
—
0
0
46
371
1.24
0.71
2.6
3.3
—
—
—
0
0
85
729
1.17
0.71
1.9
1.6
316.25
312.47
mu/l
0.03
77
665
49
400
1.23
0.69
1.3
1.2
—
—
—
0
0
49
401
1.22
0.68
1.4
1.5
50.30
60.49
%
0.84
27
244
7
121
0.58
0.67
1.6
2.3
124.14
924.24
e6/l
—
7
89
13
86
1.51
0.66
1.5
1.5
—
—
—
0
0
87
754
1.16
0.65
3.0
3.9
—
—
—
0
0
28
215
1.30
0.65
5.0
6.6
—
—
—
0
0
34
270
1.26
0.62
1.1
1.1
4.37
2.95
u/ml
0.15
14
104
110
974
1.13
0.62
1.2
1.2
—
—
—
0
0
6
104
0.58
0.61
1.2
2.0
—
—
—
0
0
369
3470
1.07
0.60
5.0
7.4
95.57
95.56
%
0.00
351
3339
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
10
64
1.56
0.58
4.0
2.6
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
46
382
1.21
0.58
1.1
1.1
1.89
3.56
u/ml
0.80
14
154
17
123
1.38
0.57
2.6
1.9
18.53
20.02
ug/l
0.20
17
110
22
287
0.77
0.57
1.4
1.3
1.40
1.48
nmol/l
0.15
22
259
6
35
1.72
0.57
1.2
2.6
0.67
0.80
u/field
—
6
35
122
1094
1.12
0.57
2.9
3.4
1.94
1.44
ratio
0.28
13
86
24
309
0.78
0.57
1.1
1.1
—
—
—
0
0
98
868
1.13
0.56
1.4
1.2
232.00
886.30
titre
—
5
27
22
167
1.32
0.56
1.1
1.2
—
—
—
0
0
806
8356
0.96
0.55
1.3
1.4
—
—
—
0
0
295
2766
1.07
0.54
4.6
4.1
—
—
—
0
0
121
1091
1.11
0.53
8.8
10.7
—
—
—
0
0
255
2728
0.93
0.52
4.5
7.7
—
—
—
0
0
42
501
0.84
0.52
1.1
1.2
288.82
280.32
u/ml
0.06
22
309
9
64
1.41
0.51
1.9
1.3
—
—
—
0
0
47
398
1.18
0.50
1.6
1.7
—
—
—
0
0
16
118
1.36
0.50
1.8
2.0
51.67
57.31
ug/l
0.25
16
113
95
850
1.12
0.49
3.3
3.5
—
—
—
0
0
35
290
1.21
0.47
1.4
1.5
—
—
—
0
0
40
337
1.19
0.46
1.1
1.1
1.03
1.42
u/ml
0.21
22
169
11
77
1.43
0.45
1.2
1.1
—
—
—
0
0
11
77
1.43
0.45
1.2
1.1
—
—
—
0
0
11
77
1.43
0.45
1.2
1.1
—
—
—
0
0
7
50
1.40
0.45
1.0
1.1
—
—
—
0
0
27
219
1.23
0.45
1.4
1.5
76.89
81.72
umol/l
0.39
27
219
7
51
1.37
0.44
1.1
1.5
—
—
—
0
0
25
202
1.24
0.43
1.2
1.1
—
—
—
0
0
74
659
1.13
0.43
4.0
3.7
56.49
57.73
%
0.33
74
659
48
553
0.87
0.42
1.3
1.3
—
—
—
0
0
5
32
1.56
0.42
12.8
11.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
9.3
—
167.83
—
0
12
166
1546
1.08
0.40
1.6
1.7
1.60
1.55
g/l
0.26
142
1322
21
168
1.25
0.40
5.2
13.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
3.1
—
—
—
0
0
54
475
1.14
0.39
2.5
2.1
—
—
—
0
0
22
178
1.24
0.38
1.1
1.2
1.00
1.04
ratio
—
7
58
39
336
1.16
0.37
1.7
1.5
0.27
0.30
nmol/l
0.17
26
247
35
299
1.17
0.37
1.1
1.2
—
—
—
0
0
16
125
1.28
0.37
1.2
1.5
33.44
30.73
umol/l
0.50
16
120
17
134
1.27
0.36
1.1
1.2
—
—
—
0
0
43
374
1.15
0.36
2.1
2.3
1.01
1.33
g/24h
0.24
18
182
34
290
1.17
0.36
1.1
1.1
—
—
—
0
0
15
191
0.78
0.36
1.4
1.5
—
—
—
0
0
9
70
1.29
0.36
1.3
1.4
—
—
—
0
0
85
773
1.10
0.36
3.2
3.2
0.88
0.81
nmol/l
0.27
68
589
166
1769
0.94
0.35
4.6
8.7
24.51
24.39
mmol/l
0.18
157
1716
16
126
1.27
0.35
2.4
2.3
—
—
—
0
0
66
594
1.11
0.34
1.2
1.6
—
—
—
0
0
6
45
1.33
0.33
1.3
1.4
—
—
—
0
0
99
912
1.09
0.33
5.9
4.5
—
—
—
0
0
89
817
1.09
0.32
1.5
1.6
8001.58
13404.05
e6/l
1.14
66
590
42
369
1.14
0.32
1.0
1.1
0.93
1.27
u/ml
0.28
16
150
18
220
0.82
0.32
1.9
1.5
0.86
0.96
g/l
1.03
18
220
6
47
1.28
0.32
1.2
1.4
73.27
76.49
%
—
6
41
49
437
1.12
0.31
1.3
1.9
—
—
—
0
0
7
96
0.73
0.30
1.6
2.1
—
—
—
0
0
28
240
1.17
0.30
1.4
1.5
12.61
13.44
u/l
0.37
28
230
24
282
0.85
0.29
2.3
2.4
—
—
—
0
0
15
185
0.81
0.29
2.0
2.7
7.42
7.42
ph
—
8
65
47
524
0.90
0.29
1.2
1.2
—
—
—
0
0
98
911
1.08
0.28
2.9
2.6
—
—
—
0
0
32
280
1.14
0.27
1.9
1.9
3.08
4.41
mg/l
2.12
32
271
48
433
1.11
0.26
1.2
1.1
12.24
13.74
au/ml
—
5
16
27
234
1.15
0.26
1.1
1.0
289.96
291.99
mg/l
0.06
27
210
8
67
1.19
0.26
3.6
6.5
—
—
—
0
0
27
235
1.15
0.25
2.2
2.5
—
—
—
0
0
31
351
0.88
0.25
1.3
1.5
—
—
—
0
0
12
96
1.25
0.24
1.2
1.1
—
—
—
0
0
15
124
1.21
0.24
1.4
1.8
—
—
—
0
0
52
475
1.10
0.23
1.1
1.1
1.11
1368.52
iu/ml
—
9
96
44
485
0.91
0.23
1.3
1.4
107.35
123.79
u/ml
0.67
11
97
96
901
1.07
0.23
3.2
4.2
7.42
7.42
ph
0.05
91
820
55
599
0.92
0.23
1.3
1.5
—
—
—
0
0
5
38
1.32
0.23
1.8
1.3
3.28
858071.76
nmol/l
—
5
31
332
3218
1.03
0.23
5.4
7.8
123.75
120.41
g/l
2.59
321
3129
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
7
94
0.74
0.22
1.0
1.1
—
—
—
0
0
10
79
1.27
0.22
1.2
1.1
—
—
—
0
0
42
381
1.10
0.22
1.0
1.3
—
—
—
0
0
5
41
1.22
0.22
1.8
1.1
—
—
—
0
0
5
41
1.22
0.22
1.8
1.1
—
—
—
0
0
5
41
1.22
0.22
1.8
1.1
—
—
—
0
0
158
1653
0.95
0.22
1.5
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
6.2
—
401.40
—
0
10
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
86
808
1.07
0.21
2.3
2.9
1.40
1.61
mg/l
2.37
78
727
81
863
0.94
0.21
1.3
1.4
—
—
—
0
0
80
750
1.07
0.21
1.2
1.2
—
—
—
0
0
46
421
1.09
0.21
1.3
1.5
2239.64
2096.46
e6/l
0.09
39
315
15
177
0.85
0.21
1.9
1.3
1.57
1.60
g/l
0.16
15
177
0
13
0.00
0.21
0.0
1.1
—
12.38
—
0
6
42
383
1.10
0.20
1.4
2.6
—
—
—
0
0
58
625
0.93
0.20
1.6
1.7
1.08
0.81
nmol/l
0.61
45
511
6
48
1.25
0.20
1.7
1.4
—
—
—
0
0
55
509
1.08
0.20
1.1
1.1
—
—
—
0
0
13
108
1.20
0.20
1.2
1.4
3.70
3.06
mmol/l
0.43
13
98
34
307
1.11
0.20
1.1
1.1
323.16
365.99
nmol/l
0.51
25
257
24
271
0.88
0.20
1.1
1.2
—
—
—
0
0
32
288
1.11
0.20
1.4
2.0
4.54
2.00
u/field
0.53
13
105
24
270
0.89
0.19
1.1
1.2
—
—
—
0
0
21
238
0.88
0.18
1.0
1.2
—
127.14
—
0
7
284
2921
0.97
0.18
4.0
6.4
1.35
1.36
mmol/l
0.08
274
2850
187
1805
1.04
0.18
6.2
9.9
—
—
—
0
0
5
68
0.73
0.17
1.0
1.1
—
7.21
pmol/l
—
0
9
46
495
0.93
0.16
1.6
1.3
—
—
—
0
0
26
288
0.90
0.16
1.2
1.1
—
—
—
0
0
18
204
0.88
0.16
1.3
1.4
—
—
—
0
0
23
256
0.90
0.16
1.5
2.3
—
—
—
0
0
13
111
1.17
0.15
1.3
1.1
—
—
—
0
0
6
77
0.78
0.15
1.8
1.4
—
—
—
0
0
6
80
0.75
0.15
1.2
1.6
—
—
—
0
0
9
82
1.10
0.15
1.4
2.0
1.87
1.34
mmol/l
—
9
76
9
82
1.10
0.15
1.1
1.1
—
—
—
0
0
26
236
1.10
0.14
1.0
1.1
27.88
35.10
mmol/l
1.05
21
201
51
543
0.94
0.14
1.3
1.4
—
—
—
0
0
28
306
0.91
0.14
2.9
2.9
35.01
32.66
mg/l
0.03
20
218
21
189
1.11
0.13
1.6
1.6
2.89
4.53
ug/l
0.44
14
152
349
3559
0.98
0.13
1.5
1.5
—
—
—
0
0
301
2947
1.02
0.13
5.5
7.0
9.31
10.23
mmol/l
1.66
276
2806
42
393
1.07
0.13
1.2
1.1
—
—
—
0
0
414
4071
1.02
0.12
1.6
1.6
—
—
—
0
0
23
252
0.91
0.12
1.3
2.0
10.82
10.98
%
0.07
23
252
42
394
1.07
0.12
1.2
1.1
—
—
—
0
0
36
336
1.07
0.12
1.4
1.5
—
—
—
0
0
183
1784
1.03
0.11
4.3
3.6
—
—
—
0
0
34
364
0.93
0.11
1.5
1.6
—
—
—
0
0
40
376
1.06
0.11
1.3
1.4
93552.96
73119.65
e6/l
0.15
27
226
19
172
1.11
0.11
3.1
3.1
—
—
—
0
0
30
321
0.93
0.10
1.3
1.4
29.53
30.16
%
0.03
15
197
55
575
0.96
0.09
1.3
1.9
—
—
—
0
0
5
47
1.06
0.09
1.2
1.3
—
—
—
0
0
16
145
1.10
0.09
1.3
1.5
173.32
210.05
pmol/l
0.21
16
145
12
107
1.12
0.08
1.9
1.4
69.58
137.87
nmol/24h
0.58
12
107
23
214
1.08
0.08
1.3
1.4
1.22
1.16
promille
0.07
15
163
57
548
1.04
0.08
1.3
1.2
—
—
—
0
0
308
3037
1.02
0.08
1.5
1.5
—
—
—
0
0
5
63
0.79
0.08
2.2
1.8
—
—
—
0
0
16
146
1.10
0.08
1.1
1.1
—
4.00
iu/ml
—
0
6
76
737
1.03
0.07
2.6
3.3
1162.89
862.12
u/ml
0.10
68
675
34
323
1.05
0.07
1.3
1.4
29467.22
88079.44
e6/l
0.83
18
227
296
2922
1.01
0.07
4.1
3.8
1.23
1.23
mmol/l
0.37
254
2531
12
108
1.11
0.07
1.1
1.1
—
—
—
0
0
25
235
1.06
0.07
1.2
1.3
—
—
—
0
0
8
78
1.03
0.07
1.0
1.1
—
—
—
0
0
55
570
0.96
0.07
1.3
1.9
—
—
—
0
0
9
84
1.07
0.07
1.0
1.2
—
—
—
0
0
13
118
1.10
0.07
1.2
1.6
2.15
2.05
umol/l
0.19
13
109
9
87
1.03
0.07
1.1
1.4
19.89
22.01
%
—
9
72
1042
10477
0.99
0.07
3.1
3.0
—
—
—
0
0
9
101
0.89
0.06
1.4
1.5
10.63
23.57
%
—
9
92
9
100
0.90
0.06
2.4
1.3
—
—
—
0
0
10
111
0.90
0.06
1.3
1.6
2.37
2.79
%
—
10
91
54
523
1.03
0.06
1.3
2.0
—
—
—
0
0
25
237
1.06
0.05
1.0
1.1
0.03
0.26
u/ml
—
8
75
14
129
1.09
0.05
1.8
2.6
—
—
—
0
0
325
3221
1.01
0.05
2.0
2.1
0.22
0.21
g/l
1.93
305
3002
26
271
0.96
0.04
1.0
1.2
—
—
—
0
0
130
1283
1.01
0.04
2.9
3.3
108.15
3469.92
u/ml
0.90
111
1076
315
3128
1.01
0.03
1.4
1.4
—
—
—
0
0
56
572
0.98
0.03
1.3
1.9
—
—
—
0
0
10
92
1.09
0.03
1.0
1.9
—
—
—
0
0
11
102
1.08
0.03
1.0
1.1
1433.18
1635.92
miu/ml
0.21
11
102
36
352
1.02
0.01
1.6
1.4
271.32
276.28
mosm/kgh2o
0.60
28
270
422
4230
1.00
0.01
4.9
6.5
104.09
104.23
mmol/l
0.25
422
4225
48
473
1.01
0.01
2.4
2.8
—
—
—
0
0
13
128
1.02
0.00
1.0
1.2
—
—
—
0
0
56
565
0.99
0.00
1.3
1.9
—
—
—
0
0
13
131
0.99
0.00
1.2
1.6
68.23
66.62
%
0.06
13
104
20
201
0.99
0.00
2.0
2.0
520.29
496.87
min
0.42
14
149
27
271
1.00
0.00
2.0
2.2
723.61
633.21
ml
0.34
18
176
35
351
1.00
0.00
1.1
1.2
—
—
—
0
0
42
419
1.00
0.00
1.7
1.7
—
—
—
0
0
11
106
1.04
0.00
1.2
1.2
—
—
—
0
0
137
1369
1.00
0.00
1.6
1.8
—
—
—
0
0
48
477
1.01
0.00
1.4
1.3
—
—
—
0
0
46
457
1.01
0.00
1.2
1.2
2.75
4.83
u/ml
1.51
24
187
63
627
1.00
0.00
2.3
2.9
—
—
—
0
0
10
103
0.97
0.00
1.0
1.1
—
—
—
0
0
16
157
1.02
0.00
3.2
2.6
617.75
1107.04
u/ml
1.62
16
157
7
74
0.95
-0.00
1.0
1.5
22.31
25.63
g/l
—
7
59
0
6
0.00
-0.00
0.0
1.5
—
3513.33
—
0
6
6
62
0.97
-0.00
3.7
7.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
154.83
—
0
6
18
180
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.95
-0.00
1.1
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
153.86
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
4.0
7.5
—
—
—
0
0
7
74
0.95
-0.00
5.4
4.7
—
—
—
0
0
8
80
1.00
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
25.80
—
0
5
11
110
1.00
-0.00
1.5
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
1.30
—
0
6
66
660
1.00
-0.00
1.5
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_MENIERE and mortality.

Females

Parameter HR [95% CI] p-value
H8_MENIERE 0.876 [0.8, 0.96] 0.006
Birth year 0.991 [0.98, 1.0] 0.033

During the follow-up period (1.1.1998 — 31.12.2019), 1902 out of 13148 females with H8_MENIERE died.

Males

Parameter HR [95% CI] p-value
H8_MENIERE 0.777 [0.71, 0.85] < 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 1269 out of 7015 males with H8_MENIERE died.

Mortality risk

Mortality risk for people of age

years, who have H8_MENIERE.

N-year risk Females Males
1 0.092% 0.158%
5 0.431% 0.937%
10 1.069% 2.318%
15 2.118% 4.412%
20 3.919% 7.457%

Relationships between endpoints

Index endpoint: H8_MENIERE – Ménière disease

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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