Oher contracture of tendon (sheath)

M13_TENDONCONTRACT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M67.1 Cause of death: ICD-10 — M67.1 2 out of 7 registries used, show all original rules.	127
4. Check minimum number of events None	127
5. Include endpoints None	127
6. Filter based on genotype QC (FinnGen only)	125

Control definitions (FinnGen only)

Control exclude: M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M67
Name in latin: Alia contractura tendinis et vaginae tendinis

NAME	M13_TENDONCONTRACT
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M671
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M671
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Oher contracture of tendon (sheath) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	895	394	498
Only index persons	856	381	475
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	54.47	52.79	55.66
Only index persons	53.77	52.82	54.53

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	125	64	61
Unadjusted period prevalence (%)	0.03	0.02	0.03
Median age at first event (years)	55.70	53.29	58.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
127: Matched controls
1270

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M67.1

ICD-10 Finland

Other contracture of tendon (sheath)

+∞

183.4

127

M72.0

ICD-10 Finland

Palmar fascial fibromatosis [Dupuytren]

165.6

35.8

NDM10

NOMESCO Finland

Palmar fasciotomy of hand

372.3

30.1

G56.0

ICD-10 Finland

Carpal tunnel syndrome

7.3

20.0

NDM40

NOMESCO Finland

Discission of sheath of tendon of wrist or hand

168.6

14.8

M75.1

ICD-10 Finland

Rotator cuff syndrome

4.9

14.0

106

M65.3

ICD-10 Finland

Trigger finger

15.9

11.4

M67.4

ICD-10 Finland

Ganglion

13.7

11.3

NDM20

NOMESCO Finland

Excision of synovial ganglion of wrist or hand

119.5

10.6

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

4.4

10.4

ACC51

NOMESCO Finland

Release of median nerve

9.1

10.1

ZXA05

NOMESCO Finland

Left side

3.4

9.0

160

M19.0

ICD-10 Finland

Primary arthrosis of other joints

5.1

8.4

N02AX02

ATC

tramadol; systemic, rectal

2.9

8.0

314

NBG15

NOMESCO Finland

Acromioplastia, arthroscopic

21.5

7.3

L12

ICPC

Hand/finger symptom/complaint

3.5

6.9

S46.0

ICD-10 Finland

Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder

6.4

6.7

R4120

NOMESCO Finland

Occupational therapy

7.2

6.6

NHL68

NOMESCO Finland

Tenodesis, shortening or lengthening of tendon of foot

73.4

6.5

7286A

ICD-9 Finland

Disorders of muscle, ligament and fascia, Contracture of palmar fascia

+∞

6.3

NBT60

NOMESCO Finland

Forcible manipulation of humeroscapular joint

+∞

6.3

M79.6

ICD-10 Finland

Pain in limb

2.6

6.1

238

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

2.7

6.1

195

L15

ICPC

Knee symptom/complaint

2.8

6.0

155

ND2AA

NOMESCO Finland

Hand and fingers X-ray examination

3.9

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40760892) CBC W Ordered Manual Differential panel - Blood

432

2.38

5.43

7.2

6.0

—

(3019198) Lymphocytes [#/volume] in Blood

475

2.34

5.16

6.3

5.4

1.92

1.78

e9/l

0.83

431

(3006315) Basophils [#/volume] in Blood

469

2.31

5.04

6.3

5.4

0.04

e9/l

0.25

416

(3001604) Monocytes [#/volume] in Blood

470

2.30

5.00

6.4

5.4

0.57

0.58

e9/l

0.01

416

(3013115) Eosinophils [#/volume] in Blood

480

2.30

4.97

6.4

5.7

0.22

0.19

e9/l

0.65

432

(3018010) Neutrophils/100 leukocytes in Blood

437

2.27

4.88

5.7

5.4

55.87

58.14

0.74

417

(3022096) Basophils/100 leukocytes in Blood

422

2.24

4.77

6.3

5.3

0.73

0.69

0.27

401

(3002030) Lymphocytes/100 leukocytes in Blood

449

2.25

4.76

6.3

5.5

28.05

27.44

0.16

429

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

124

2.61

4.36

1.3

1.2

1.31

15.25

u/ml

—

(3006504) Eosinophils/100 leukocytes in Blood

435

2.14

4.28

6.5

5.3

3.04

2.81

0.33

414

(3019069) Monocytes/100 leukocytes in Blood

439

2.11

4.14

6.7

5.6

9.12

8.74

0.41

418

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

372

2.03

3.69

2.1

1.8

94.79

94.56

pmol/l

0.01

198

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

149

2.23

3.23

1.6

1.9

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

119

1047

3.17

3.21

21.6

14.6

139.81

139.78

mmol/l

0.04

119

1015

(3022217) INR in Platelet poor plasma by Coagulation assay

443

1.90

3.12

11.8

12.3

1.24

1.22

inr

0.05

123

(3044290) Cell count panel - Cerebral spinal fluid

7.80

3.09

1.0

1.6

—

(3013707) Erythrocyte sedimentation rate by Westergren method

700

1.98

3.05

4.9

3.7

12.60

11.77

mm/h

0.22

641

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

131

2.24

3.03

1.2

24.27

52.99

iu/ml

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

297

1.92

3.00

4.1

2.1

55.67

55.85

u/l

0.02

271

(3007853) Bacteria identified in Skin by Aerobe culture

2.45

2.87

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

579

1.84

2.78

3.1

2.8

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

121

1094

3.24

2.67

13.9

9.7

25.41

26.65

u/l

0.39

121

1055

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

184

1.99

2.65

1.6

0.77

1.20

mg/l

1.33

148

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

117

1031

2.71

2.50

5.3

4.9

2.63

2.77

mmol/l

1.02

110

957

(3023368) Bacteria identified in Blood by Culture

245

1.85

2.47

5.8

4.3

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

553

1.75

2.45

8.1

9.4

3.89

4.21

e9/l

0.75

491

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

107

915

2.08

2.37

5.2

4.0

1.94

2.01

mu/l

0.28

820

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

114

1002

2.35

2.29

4.5

4.3

1.45

1.47

mmol/l

0.13

107

928

(40761511) CBC panel - Blood by Automated count

118

1066

2.51

2.21

19.6

12.2

—

(3037467) Urinalysis macro (dipstick) panel - Urine

663

1.73

2.21

5.4

3.8

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

107

922

2.02

2.21

6.8

5.7

41.83

40.07

mmol/mol

0.90

100

859

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

727

1.75

2.16

4.2

3.4

15.04

14.74

pmol/l

0.49

649

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

105

2.07

2.10

1.5

1.8

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

111

974

2.11

2.10

4.1

3.9

1.14

1.29

mmol/l

2.19

105

900

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

113

1001

2.17

2.03

19.8

12.8

26.72

25.01

mg/l

0.22

101

759

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

107

2.03

2.00

1.5

1.7

—

(3019309) Folate [Moles/volume] in Red Blood Cells

162

1.85

1.95

1.7

1.6

1271.35

1184.51

nmol/l

0.16

128

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

441

1.63

1.95

2.7

2.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.34

1.91

1.7

3.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.12

1.84

2.8

3.5

—

(4200892) Spirometry reversibility

2.16

1.84

1.9

1.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.97

1.72

1.3

1.5

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

307

1.61

1.66

3.0

3.6

2.36

2.35

mmol/l

0.17

274

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

195

1.70

1.66

1.2

1.28

0.60

u/ml

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.44

1.63

8.3

7.2

—

(3044889) 12 lead EKG panel

715

1.57

4.2

3.7

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.33

1.50

8.9

5.3

23.41

24.69

mmol/l

—

(3012516) Albumin [Mass/volume] in Urine

296

1.57

1.50

4.4

3.3

26.63

77.49

mg/l

1.83

195

(3021901) Oxygen saturation in Capillary blood

3.21

1.45

3.2

2.7

—

(3019225) pH of Specimen

1.89

1.41

4.5

5.3

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.22

1.37

1.2

1.9

2.12

4.57

mg/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

421

1.49

1.37

8.0

6.0

1.21

mmol/l

0.00

389

(1616796) Gas panel - Central venous blood

3.02

1.37

8.6

3.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

461

1.48

1.33

9.4

6.9

1.21

mmol/l

0.11

397

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.37

1.29

2.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.37

1.29

1.1

1.0

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.70

1.22

1.2

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

2.70

1.22

1.2

0.00

g/l

—

(3037522) Nuclear Ab [Titer] in Serum

111

1.72

1.20

1.2

1.3

373.33

303.70

titre

—

(3009508) Creatinine [Moles/volume] in Urine

310

1.48

1.19

4.2

3.1

7.46

8.07

mmol/l

0.47

267

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

120

1.69

1.17

13.8

7.8

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

1.84

1.11

2.0

2.6

75.67

60.65

ml/min/173m2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.25

1.10

1.1

1.2

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.18

1.07

2.0

1.7

—

(3020682) Albumin/Creatinine [Ratio] in Urine

316

1.44

1.07

4.9

3.8

5.03

12.93

mg/mmol

1.21

203

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.03

1.06

2.7

2.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.32

1.04

1.0

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.32

1.04

1.2

1.0

—

(40760888) Immunoglobulin light chains.free panel - Serum

2.32

1.04

1.6

6.1

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.94

1.03

1.2

1.7

—

(3019060) Gas panel - Arterial blood

1.85

0.97

4.7

3.5

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.12

0.90

5.2

2.7

—

(40768443) Skin Pathology biopsy report

1.96

0.90

1.8

1.3

—

(3003396) Base excess in Arterial blood by calculation

105

1.60

0.86

8.2

5.5

0.09

0.87

mmol/l

0.43

(3009261) Glucose [Presence] in Urine by Test strip

479

1.34

0.86

5.1

3.3

0.00

estimate

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.98

0.85

1.5

4.7

38.33

101.21

mg/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.98

0.85

1.5

4.7

30.18

36.77

mg/l

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

174

1.47

0.85

4.5

3.6

46.00

198.48

ng/l

1.22

141

(3018418) pH of Serum or Plasma

291

1.38

0.85

6.3

4.4

7.40

—

(3021589) Normoblasts [#/volume] in Blood

442

1.34

0.84

12.5

8.9

0.00

0.01

e9/l

0.50

362

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

123

1.54

0.83

3.9

2.6

19.35

22.85

0.57

110

(4034850) Laboratory test

1.92

0.83

21.2

8.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.75

0.82

1.5

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.79

0.82

1.6

1.4

—

(36660697) Celiac disease serology panel - Serum

1.73

0.81

1.3

1.2

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

176

1.45

0.80

3.3

2.4

2.31

1.10

e6/l

0.71

106

(3035350) Ketones [Presence] in Urine by Test strip

476

1.32

0.77

5.1

3.3

0.00

estimate

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.13

0.75

1.8

1.3

—

(40761535) Cells panel - Urine sediment

1.64

0.74

3.9

3.8

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.79

0.72

1.1

1.2

—

(3000492) Spirometry study

1.59

0.72

1.4

1.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

374

1.31

0.71

3.9

3.7

21.87

32.85

ng/l

0.86

256

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.70

0.69

2.3

4.8

23.47

24.31

mmol/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

475

1.28

0.65

6.6

4.5

0.00

estimate

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.67

0.63

1.3

2.0

1.19

1.36

g/l

—

(3025941) Bacteria identified in Stool by Culture

1.61

0.62

1.1

1.4

—

(3042936) Bacteria identified in Isolate by Culture

132

1.42

0.61

2.2

2.0

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.60

0.0

1.5

—

5.80

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.60

0.0

3.5

—

59.00

—

(3026008) Bacteria identified in Urine by Culture

271

1.29

0.56

5.5

2.6

—

(3013512) EKG study

281

1.29

0.55

5.2

3.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.48

0.55

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

207

1.32

0.55

4.8

3.1

—

(3022313) Gas panel - Capillary blood

1.59

0.50

5.6

4.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

111

1.40

0.49

1.7

1.5

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

203

1.29

0.47

1.6

1.7

611111540.61

412.86

pmol/l

0.48

182

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

383

1.23

0.46

5.2

3.5

—

(3030467) Casts [#/volume] in Urine by Automated count

279

1.25

0.45

4.8

2.8

0.57

0.49

e6/l

0.06

207

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

131

1.34

0.45

1.7

1.6

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.41

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.41

0.0

1.1

—

(40768804) Tissue Pathology biopsy report

397

1.21

0.41

1.9

2.1

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.41

0.0

1.9

—

67.00

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

369

1.21

0.40

4.8

2.9

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.45

0.40

1.0

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.39

0.39

4.3

2.7

128.22

127.59

g/l

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

305

1.20

0.36

5.5

4.4

22.05

20.59

0.26

152

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.35

0.34

1.0

2.6

51.17

37.79

u/l

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

221

1.22

0.34

3.4

2.9

0.63

0.93

ug/l

1.18

148

(3014576) Chloride [Moles/volume] in Serum or Plasma

119

1.30

0.33

5.0

4.6

105.67

104.50

mmol/l

0.50

119

(40768797) Stomach Pathology biopsy report

119

1.30

0.33

1.2

—

(40758558) Short blood count panel - Blood

250

1.21

0.33

3.7

7.4

—

(3000330) Specific gravity of Urine by Test strip

1.29

0.33

9.7

4.0

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.34

0.31

1.6

3.6

62.71

50.91

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.26

0.30

1.6

—

(3007164) IgA [Mass/volume] in Serum or Plasma

196

1.21

0.29

1.3

1.4

2.51

2.30

g/l

0.43

126

(3014007) Fractional oxyhemoglobin in Arterial blood

1.24

0.29

12.1

5.8

92.33

94.64

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

159

1.23

0.29

3.8

2.6

2.85

2.01

e6/l

0.25

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

226

1.19

0.28

2.5

2.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

101

974

1.18

0.27

15.8

12.3

79.80

80.13

ml/min/173m2

0.05

790

(3029937) Albumin [Presence] in Urine by Test strip

257

1.17

0.25

5.3

3.7

0.00

estimate

—

(3000494) Fungus identified in Specimen by Culture

115

1.24

0.25

1.5

1.4

—

(36304419) Bacteria [Presence] in Urine

268

1.16

0.23

4.4

2.6

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.29

0.23

1.2

1.4

—

(3020891) Body temperature

1.26

0.22

3.8

4.1

—

(3002582) Erythrocytes [#/volume] in Urine

308

1.14

0.22

4.8

2.9

91.77

43.99

e6/l

0.34

236

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

100

0.79

0.22

2.4

1.7

—

(3018095) Leukocytes [#/volume] in Urine

357

1.13

0.22

4.9

3.2

307.47

88.22

e6/l

0.44

259

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.1

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.21

0.0

2.4

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.21

0.0

1.0

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.21

0.0

3.2

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

1.8

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.21

0.0

1.1

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.8

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.2

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.74

0.17

2.0

1.5

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.19

0.17

6.4

4.5

95.50

90.21

ng/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.15

0.16

1.4

1.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.12

0.16

2.8

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.77

0.16

1.0

2.2

—

(3044640) Blood type and Crossmatch panel - Blood

306

1.11

0.15

2.6

2.2

—

(3022145) Colonoscopy Study observation

103

1.18

0.14

1.6

1.4

—

(4035726) Immunohistochemistry procedure

0.80

0.14

1.5

1.4

—

(3000991) Gas panel - Venous blood

1.16

0.10

8.7

6.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

155

1.11

0.09

1.7

1.9

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.04

0.09

2.0

3.1

3.30

4.25

pmol/l

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

146

1.11

0.08

1.5

1.6

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

403

1.06

0.08

3.3

2.4

133.25

111.42

ug/l

0.29

374

(3019832) Treponema pallidum Ab [Presence] in Serum

1.07

0.07

1.3

1.8

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.82

0.07

1.0

2.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

278

1.06

0.05

4.9

3.1

—

(3002256) Pathology report gross observation

128

0.93

0.03

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

158

0.94

0.02

1.3

1.4

—

(21494755) Public health laboratory ask at order entry panel

111

0.99

0.00

1.3

1.4

—

(3003694) ABO and Rh group [Type] in Blood

258

1.01

0.00

1.3

1.4

—

(1761868) Lipid panel - Serum or Plasma

389

1.00

0.00

2.8

2.7

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

256

1.02

0.00

1.4

1.6

1.23

1.40

mmol/l

0.54

211

(40761536) Microorganisms panel - Urine sediment

0.89

0.00

7.3

3.2

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.0

—

0.60

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.3

—

(3022621) pH of Urine by Test strip

1.02

-0.00

2.2

2.1

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3014271) Vancomycin [Susceptibility]

0.00

-0.00

0.0

1.6

—

(3044007) Cell count panel - Peritoneal fluid

0.00

-0.00

0.0

1.2

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

4.0

—

2530.00

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.6

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.2

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

29.48

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.2

—

(3036603) Volume of Urine

0.00

-0.00

0.0

2.3

—

1357.50

—

(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

16.30

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.8

—

(3020650) Glucose [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.2

—

9.98

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

1.65

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.6

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

-0.00

0.0

1.8

—

85.18

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.01

-0.00

1.3

1.5

314.63

368.27

nmol/l

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

841.50

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3024263) Appearance of Synovial fluid

0.00

-0.00

0.0

1.2

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.2

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

5.3

—

5.80

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.0

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

1.0

—

11.11

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.1

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

-0.00

0.0

1.8

—

7.55

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_TENDONCONTRACT and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
M13_TENDONCONTRACT	0.751 [0.57, 0.99]	0.041
Birth year	0.991 [0.98, 1.0]	0.042

During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 451 males with M13_TENDONCONTRACT died.

Mortality risk

Mortality risk for people of age

years, who have M13_TENDONCONTRACT.

N-year risk	Females	Males
1	No data	0.162%
5	No data	0.972%
10	No data	2.63%
15	No data	4.932%
20	No data	8.201%

Relationships between endpoints

↥

Index endpoint: M13_TENDONCONTRACT – Oher contracture of tendon (sheath)

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Oher contracture of tendon (sheath)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints