Oher contracture of tendon (sheath)

M13_TENDONCONTRACT

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M67.1 Cause of death: ICD-10 — M67.1 2 out of 7 registries used, show all original rules.	127
4. Check minimum number of events None	127
5. Include endpoints None	127
6. Filter based on genotype QC (FinnGen only)	127

Control definitions (FinnGen only)

Control exclude: M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M67
Name in latin: Alia contractura tendinis et vaginae tendinis

NAME	M13_TENDONCONTRACT
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M671
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M671
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Oher contracture of tendon (sheath) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	895	394	498
Only index persons	856	381	475
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	54.47	52.79	55.66
Only index persons	53.77	52.82	54.53

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	127	66	61
Unadjusted period prevalence (%)	0.02	0.02	0.03
Median age at first event (years)	55.66	53.29	58.23

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
115: Matched controls
1151

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M67.1

ICD-10 Finland

Other contracture of tendon (sheath)

+∞

166.0

115

M72.0

ICD-10 Finland

Palmar fascial fibromatosis [Dupuytren]

219.0

32.5

NDM10

NOMESCO Finland

Palmar fasciotomy of hand

332.1

26.9

G56.0

ICD-10 Finland

Carpal tunnel syndrome

9.2

15.1

NDM40

NOMESCO Finland

Discission of sheath of tendon of wrist or hand

+∞

14.9

M65.3

ICD-10 Finland

Trigger finger

35.1

14.4

NDM20

NOMESCO Finland

Excision of synovial ganglion of wrist or hand

+∞

11.7

M67.4

ICD-10 Finland

Ganglion

19.7

11.6

M75.1

ICD-10 Finland

Rotator cuff syndrome

4.8

9.8

100

ACC51

NOMESCO Finland

Release of median nerve

9.1

8.8

M19.0

ICD-10 Finland

Primary arthrosis of other joints

7.4

8.1

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

14.7

7.6

N02AX02

ATC

tramadol; systemic, rectal

3.0

7.3

276

NBG15

NOMESCO Finland

Acromioplastia, arthroscopic

42.6

6.8

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

4.1

6.8

M71.2

ICD-10 Finland

Synovial cyst of popliteal space [Baker]

73.8

6.5

NBT60

NOMESCO Finland

Forcible manipulation of humeroscapular joint

+∞

6.3

ND2AA

NOMESCO Finland

Hand and fingers X-ray examination

6.2

6.3

M75.0

ICD-10 Finland

Adhesive capsulitis of shoulder

13.5

6.2

ZXA05

NOMESCO Finland

Left side

3.3

6.2

141

N03AX12

ATC

gabapentin; oral

4.2

6.2

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(42870588) Differential panel, method unspecified - Blood

305

2.34

5.05

5.8

5.0

—

(3019198) Lymphocytes [#/volume] in Blood

478

2.31

5.04

6.2

5.3

1.9

1.8

e9/l

0.83

433

(3006315) Basophils [#/volume] in Blood

474

2.27

4.85

6.3

5.3

0.0

e9/l

0.24

420

(3001604) Monocytes [#/volume] in Blood

474

2.27

4.85

6.3

5.2

0.6

e9/l

0.04

419

(3013115) Eosinophils [#/volume] in Blood

484

2.27

4.82

6.4

5.5

0.2

e9/l

0.67

437

(3018010) Neutrophils/100 leukocytes in Blood

440

2.24

4.76

5.5

5.4

55.8

58.3

0.83

420

(3002030) Lymphocytes/100 leukocytes in Blood

452

2.22

4.65

6.1

5.5

28.6

27.4

0.35

429

(3022096) Basophils/100 leukocytes in Blood

426

2.21

4.62

6.3

5.3

0.7

0.33

406

(3006504) Eosinophils/100 leukocytes in Blood

438

2.12

4.18

6.5

5.4

3.0

2.8

0.44

414

(3019069) Monocytes/100 leukocytes in Blood

442

2.09

4.04

6.4

5.6

9.2

8.8

0.50

422

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

129

2.50

4.01

1.3

1.2

1.3

14.4

u/ml

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

375

2.01

3.58

2.1

1.8

94.8

94.5

pmol/l

0.01

204

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

148

2.24

3.29

1.6

1.8

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

119

1049

3.13

3.21

21.6

14.6

139.8

mmol/l

0.03

119

1019

(3044290) Cell count panel - Cerebral spinal fluid

7.80

3.09

1.0

1.8

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

299

1.91

2.93

4.1

2.1

55.7

56.0

u/l

0.03

272

(3007853) Bacteria identified in Skin by Aerobe culture

2.45

2.87

1.4

—

(3013707) Erythrocyte sedimentation rate by Westergren method

708

1.93

2.84

4.9

3.7

12.6

11.7

mm/h

0.26

650

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

137

2.13

2.71

1.2

24.3

52.8

iu/ml

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

582

1.82

2.70

3.1

2.9

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

121

1095

3.22

2.67

13.9

9.7

25.4

26.5

u/l

0.33

121

1058

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

186

1.96

2.56

1.6

0.8

1.2

mg/l

1.30

150

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

117

1032

2.70

2.48

5.3

4.9

2.6

2.8

mmol/l

1.00

110

959

(3023368) Bacteria identified in Blood by Culture

246

1.84

2.44

5.8

4.2

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

558

1.72

2.33

8.1

9.0

3.9

4.2

e9/l

0.78

496

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

114

1002

2.35

2.29

4.5

4.3

1.5

mmol/l

0.14

107

929

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

107

919

2.04

2.27

5.2

4.0

1.9

2.0

mu/l

0.22

825

(3032080) INR in Blood by Coagulation assay

382

1.72

2.27

9.8

7.4

1.3

1.2

inr

—

113

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

107

923

2.01

2.19

6.9

5.7

41.8

40.0

mmol/mol

0.92

100

861

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

104

2.10

2.15

1.5

1.8

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

111

973

2.12

4.1

3.9

1.1

1.3

mmol/l

2.15

105

901

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

730

1.73

2.10

4.2

3.4

15.0

14.7

pmol/l

0.49

652

(40761511) CBC panel - Blood by Automated count

118

1071

2.44

2.07

19.6

12.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

106

2.05

1.6

1.7

—

(3037467) Urinalysis macro (dipstick) panel - Urine

671

1.68

2.04

5.4

3.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

439

1.64

1.99

4.8

3.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

113

1006

2.12

1.92

19.8

12.7

26.7

25.4

mg/l

0.16

101

771

(3004588) Protein electrophoresis panel - Serum or Plasma

2.34

1.91

1.7

2.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

164

1.82

1.88

1.7

1.6

1271.4

1171.2

nmol/l

0.19

130

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.12

1.84

2.8

3.5

—

(4010399)

2.13

1.78

1.9

1.4

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

308

1.60

1.64

3.0

3.5

2.4

mmol/l

0.19

275

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

100

1.93

1.63

1.3

1.5

—

(3012516) Albumin [Mass/volume] in Urine

292

1.60

1.59

4.4

3.3

26.6

79.3

mg/l

1.88

190

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.38

1.57

8.3

7.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

105

930

1.74

1.57

18.7

13.4

38.9

40.1

0.57

683

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

199

1.66

1.54

1.2

1.3

0.6

u/ml

—

(3044889) 12 lead EKG panel

719

1.55

1.50

4.2

3.8

—

(3021901) Oxygen saturation in Capillary blood

3.21

1.45

3.2

2.7

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.27

1.44

8.9

5.2

23.4

24.7

mmol/l

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.22

1.37

1.2

1.9

2.1

4.6

mg/l

—

(1616796) Gas panel - Central venous blood

3.02

1.37

8.6

3.4

—

(3019225) pH of Specimen

1.87

1.36

4.5

5.3

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

423

1.48

1.33

8.0

5.8

1.2

mmol/l

0.02

389

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.37

1.29

2.0

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

464

1.46

1.27

9.4

6.7

1.2

mmol/l

0.13

398

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

117

1.73

1.27

13.8

8.0

—

(3009508) Creatinine [Moles/volume] in Urine

307

1.50

1.25

4.2

3.1

7.5

8.1

mmol/l

0.54

266

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.24

1.24

1.1

1.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

210

1.56

1.24

6.5

5.0

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

583

1.45

1.23

6.1

4.1

7.0

6.7

mmol/l

0.58

546

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.70

1.22

1.2

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

2.70

1.22

1.2

0.0

g/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

312

1.46

1.14

5.2

4.0

5.0

13.1

mg/mmol

1.23

200

(40768443) Skin Pathology biopsy report

2.01

1.11

1.8

1.3

—

(40760888) Immunoglobulin light chains.free panel - Serum

2.44

1.10

1.6

3.6

—

(3037522) Nuclear Ab [Titer] in Serum

114

1.67

1.10

1.2

1.3

373.3

304.3

titre

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

1.82

1.07

2.0

2.6

75.7

60.7

ml/min/173m2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.18

1.07

1.1

1.2

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.18

1.07

2.0

1.7

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.03

1.06

2.7

2.3

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.32

1.04

1.2

1.0

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.32

1.04

1.0

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.94

1.03

1.2

1.7

—

(3019060) Gas panel - Arterial blood

1.82

0.93

4.7

3.5

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.20

0.93

5.2

2.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.85

0.90

1.6

1.4

—

(3012544) pH of Venous blood

1.64

0.89

3.6

3.8

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

2.05

0.88

1.5

2.8

38.3

105.4

mg/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

2.05

0.88

1.5

2.9

30.2

32.3

mg/l

—

(3003396) Base excess in Arterial blood by calculation

105

1.60

0.86

8.2

5.5

0.1

0.8

mmol/l

0.42

(3018418) pH of Serum or Plasma

292

1.38

0.83

6.3

4.2

7.4

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

175

1.46

0.82

4.5

3.6

46.0

205.9

ng/l

1.32

143

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.75

0.82

1.5

—

(3000492) Spirometry study

1.65

0.81

1.4

1.6

—

(4034850)

1.86

0.80

21.2

8.1

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

177

1.44

0.78

3.3

2.4

2.3

1.1

e6/l

0.72

105

(40761535) Cells panel - Urine sediment

1.66

0.78

3.9

3.8

—

(3009261) Glucose [Presence] in Urine by Test strip

486

1.31

0.76

5.1

3.3

0.0

estimate

—

(3021589) Normoblasts [#/volume] in Blood

448

1.31

0.75

12.5

8.9

0.0

e9/l

0.50

367

(3003327) Ova and parasites identified in Stool by Light microscopy

2.13

0.75

1.8

1.3

—

(36660697) Celiac disease serology panel - Serum

1.68

0.74

1.3

1.1

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

128

1.47

0.70

3.9

2.5

19.4

22.6

0.51

113

(3022313) Gas panel - Capillary blood

1.66

0.68

5.6

4.6

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.66

0.68

1.1

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

483

1.29

0.67

5.1

3.3

0.0

estimate

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.55

0.66

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

379

1.29

0.64

3.9

3.6

21.8

32.9

ng/l

0.87

257

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.64

0.62

1.3

2.0

1.2

1.3

g/l

—

(3025941) Bacteria identified in Stool by Culture

1.61

0.62

1.1

1.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.60

0.0

3.5

—

59.0

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.60

0.0

1.5

—

3.0

—

(3013512) EKG study

280

1.29

0.57

5.2

3.8

—

(3021601) Nitrite [Presence] in Urine by Test strip

482

1.25

0.56

6.6

4.6

0.0

estimate

—

(3042936) Bacteria identified in Isolate by Culture

135

1.39

0.55

2.2

2.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

209

1.31

0.52

4.8

3.1

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.41

0.52

4.3

2.7

128.2

127.9

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

111

1.40

0.49

1.7

1.5

—

(3030467) Casts [#/volume] in Urine by Automated count

279

1.25

0.45

4.8

2.8

0.6

0.5

e6/l

0.07

205

(40768804) Tissue Pathology biopsy report

395

1.22

0.44

1.9

2.1

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

132

1.33

0.43

1.7

1.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

386

1.21

0.43

5.2

3.5

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

206

1.27

0.42

1.6

1.7

611111540.6

414.2

pmol/l

0.48

184

(40768795) Lymph node Pathology biopsy report

0.00

0.41

0.0

1.1

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.41

0.0

1.9

—

67.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

374

1.18

0.34

4.8

2.9

—

(3026008) Bacteria identified in Urine by Culture

269

1.20

0.33

5.8

2.6

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.32

0.33

1.0

2.6

51.2

37.2

u/l

—

(3000330) Specific gravity of Urine by Test strip

1.29

0.33

9.7

4.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

309

1.18

0.31

5.5

4.4

22.1

20.7

0.23

154

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.34

0.31

1.6

3.6

62.7

50.2

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.26

0.30

1.6

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.24

0.29

12.1

5.8

92.3

94.6

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

225

1.20

0.29

3.4

2.9

0.6

0.9

ug/l

1.18

149

(40758558) Short blood count panel - Blood

254

1.18

0.28

3.7

7.0

—

(40768797) Stomach Pathology biopsy report

122

1.26

0.28

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

226

1.19

0.28

2.5

2.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

101

975

1.18

0.26

15.7

12.3

79.8

80.1

ml/min/173m2

0.05

789

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

162

1.20

0.24

3.8

2.6

2.9

2.0

e6/l

0.25

(3007164) IgA [Mass/volume] in Serum or Plasma

200

1.18

0.24

1.3

1.4

2.5

2.3

g/l

0.42

129

(3029937) Albumin [Presence] in Urine by Test strip

258

1.16

0.24

5.3

3.6

0.0

estimate

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.37

0.24

1.0

—

(36304419) Bacteria [Presence] in Urine

268

1.16

0.23

4.4

2.7

—

(3020891) Body temperature

1.33

0.23

3.8

4.2

—

(3000494) Fungus identified in Specimen by Culture

116

1.23

0.23

1.5

1.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.29

0.23

1.2

1.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.8

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.9

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.21

0.0

2.6

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.9

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.1

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.21

0.0

1.0

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.9

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(4281824)

0.00

0.21

0.0

1.1

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

1.8

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.21

0.0

3.0

—

(3002582) Erythrocytes [#/volume] in Urine

309

1.14

0.21

4.8

2.9

91.8

44.0

e6/l

0.34

236

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.2

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.20

0.0

1.3

—

(3018095) Leukocytes [#/volume] in Urine

359

1.12

0.20

4.9

3.2

307.5

88.2

e6/l

0.44

259

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.75

0.17

2.0

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.19

0.17

1.4

1.5

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.15

0.16

6.4

4.4

95.5

88.3

ng/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.14

0.16

2.8

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.77

0.16

1.0

2.2

—

(3044640) Blood type and Crossmatch panel - Blood

305

1.11

0.15

2.6

2.2

—

(3000991) Gas panel - Venous blood

1.21

0.14

8.7

6.3

—

(4035726)

0.81

0.14

1.5

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.80

0.14

2.4

1.7

—

(3022145) Colonoscopy Study observation

104

1.17

0.13

1.6

1.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

144

1.13

0.11

1.5

1.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

154

1.12

0.10

1.7

1.8

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.04

0.09

2.0

3.2

3.3

4.3

pmol/l

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.10

0.08

1.3

1.8

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.03

0.07

1.3

1.6

314.6

366.4

nmol/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.83

0.07

1.0

2.2

—

(3002256) Pathology report gross observation

130

0.92

0.05

1.3

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

408

1.04

0.04

3.3

2.4

133.3

110.7

ug/l

0.30

379

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

160

0.93

0.04

1.3

1.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

282

1.04

0.02

4.9

3.1

—

(3003694) ABO and Rh group [Type] in Blood

257

1.01

0.00

1.3

1.4

—

(1761868) Lipid panel - Serum or Plasma

387

1.01

0.00

2.8

2.7

—

(21494755) Public health laboratory ask at order entry panel

108

1.02

0.00

1.3

1.4

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

0.0

4.8

—

5.6

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.5

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.0

—

(3020650) Glucose [Presence] in Urine

0.00

0.0

1.2

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

1.2

—

(3022621) pH of Urine by Test strip

1.00

0.00

2.2

2.3

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.2

—

10.0

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

26.3

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.0

—

(3044007) Cell count panel - Peritoneal fluid

0.00

0.0

1.2

—

(3024263) Appearance of Synovial fluid

0.00

0.0

1.2

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

1.8

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

8.5

—

0.6

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.0

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

2.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

2.6

—

(3000012) Reticulocyte production index

0.00

0.0

2.3

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

0.0

1.8

—

85.2

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.1

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

0.0

2.6

—

62.2

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

260

1.00

0.00

1.4

1.6

1.2

1.4

mmol/l

0.55

215

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

0.0

1.0

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

1.6

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

2.1

—

(40761536) Microorganisms panel - Urine sediment

0.88

0.00

7.3

3.2

—

(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

16.3

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3012565) Volume of 24 hour Urine

0.00

0.0

4.0

—

2530.0

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

1.8

—

841.5

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3011648) Oxygen content in Venous blood

0.00

0.0

1.0

—

11.1

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_TENDONCONTRACT and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
M13_TENDONCONTRACT	0.751 [0.57, 0.99]	0.041
Birth year	0.991 [0.98, 1.0]	0.042

During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 451 males with M13_TENDONCONTRACT died.

Mortality risk

Mortality risk for people of age

years, who have M13_TENDONCONTRACT.

N-year risk	Females	Males
1	No data	0.162%
5	No data	0.972%
10	No data	2.63%
15	No data	4.932%
20	No data	8.201%

Relationships between endpoints

↥

Index endpoint: M13_TENDONCONTRACT – Oher contracture of tendon (sheath)

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Oher contracture of tendon (sheath)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints