No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
127 |
4. Check minimum number of eventsNone |
127 |
5. Include endpointsNone |
127 |
6. Filter based on genotype QC (FinnGen only) |
127 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M67
- Name in latin
- Alia contractura tendinis et vaginae tendinis
Similar endpoints
↥List of similar endpoints to
Oher contracture of tendon (sheath)
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 895 | 394 | 498 |
| Only index persons | 856 | 381 | 475 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 54.47 | 52.79 | 55.66 |
| Only index persons | 53.77 | 52.82 | 54.53 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 127 | 66 | 61 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 55.66 | 53.29 | 58.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 115
- Matched controls
- 1151
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M67.1
ICD-10 Finland
Other contracture of tendon (sheath)
+∞
166.0
115
*
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
219.0
32.5
32
*
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
332.1
26.9
26
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
9.2
15.1
33
48
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
+∞
14.9
14
*
M65.3
ICD-10 Finland
Trigger finger
35.1
14.4
18
6
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
+∞
11.7
11
*
M67.4
ICD-10 Finland
Ganglion
19.7
11.6
17
10
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.8
9.8
36
100
ACC51
NOMESCO Finland
Release of median nerve
9.1
8.8
18
23
M19.0
ICD-10 Finland
Primary arthrosis of other joints
7.4
8.1
19
30
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
14.7
7.6
12
9
N02AX02
ATC
tramadol; systemic, rectal
3.0
7.3
56
276
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
42.6
6.8
8
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.1
6.8
27
80
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
73.8
6.5
7
*
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
+∞
6.3
6
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
6.2
6.3
16
29
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
13.5
6.2
10
8
ZXA05
NOMESCO Finland
Left side
3.3
6.2
36
141
N03AX12
ATC
gabapentin; oral
4.2
6.2
23
64
Mortality – FinRegistry
↥Association
Association between endpoint M13_TENDONCONTRACT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_TENDONCONTRACT | 0.751 [0.57, 0.99] | 0.041 |
| Birth year | 0.991 [0.98, 1.0] | 0.042 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 451 males with M13_TENDONCONTRACT died.
Mortality risk
Mortality risk for people of age
years, who have M13_TENDONCONTRACT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.162% |
| 5 | No data | 0.972% |
| 10 | No data | 2.63% |
| 15 | No data | 4.932% |
| 20 | No data | 8.201% |
Relationships between endpoints
↥Index endpoint: M13_TENDONCONTRACT – Oher contracture of tendon (sheath)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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