Acute hepatitis B

AB1_HEPATITIS_B

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B16
  • Hospital discharge: ICD-9 070[2-3]
  • Cause of death: ICD-10 B16
  • Cause of death: ICD-9 070[2-3]

2 out of 7 registries used, show all original rules.

162

4. Check minimum number of events

None

162

5. Include endpoints

None

162

6. Filter based on genotype QC (FinnGen only)

151

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_HEPATITIS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
B15-B19
Name in latin
Hepatitis B acuta

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1640 629 974
Only index persons 1328 541 787
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 30.79 27.28 32.85
Only index persons 30.02 26.63 32.34

-FinnGen-

Key figures

All Female Male
Number of individuals 151 74 77
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 32.73 29.03 36.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
162
Matched controls
1620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B16.9
ICD-10 Finland
Acute hepatitis B without delta-agent and without hepatic coma
+∞
123.1
102
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
16.8
58.7
58
52
0703A
ICD-9 Finland
Viral hepatitis B without mention of hepatic coma
+∞
55.4
50
*
B18.2
ICD-10 Finland
Chronic viral hepatitis C
+∞
47.2
43
*
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
+∞
26.8
25
*
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
+∞
25.7
24
*
P19
ICPC
Drug abuse
293.4
25.4
25
*
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
113.3
19.0
20
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
37.7
16.2
20
6
N05BA01
ATC
diazepam; systemic, rectal
4.8
15.5
42
110
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.5
14.9
23
35
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
+∞
14.8
14
*
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
152.2
13.7
14
*
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
152.2
13.7
14
*
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
+∞
12.7
12
*
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
+∞
12.7
12
*
F19.21
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances currently independent but staying in a controlling environment
+∞
11.6
11
*
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
+∞
11.6
11
*
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
64.4
10.8
12
*
3049X
ICD-9 Finland
Drug dependence, Unspecified drug dependence
+∞
10.5
10
*
Z72.2
ICD-10 Finland
Drug use
+∞
10.5
10
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.6
9.9
26
65
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
5.8
9.9
19
36
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
+∞
9.5
9
*
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
+∞
9.5
9
*
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
+∞
9.5
9
*
N05CD07
ATC
temazepam; oral
4.0
9.5
30
87
N05AH04
ATC
quetiapine; oral
3.0
9.1
50
207
Z2221
NOMESCO Finland
Medical doctor
2.8
8.7
61
287
3044A
ICD-9 Finland
Drug dependence, Amphetamine and other psychostimulant dependence
94.8
8.5
9
*
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
94.8
8.5
9
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
8.5
31
99
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.8
8.4
29
89
B17.1
ICD-10 Finland
Acute hepatitis C
+∞
8.4
8
*
F19.9
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, unspecified mental and behavioural disorder
+∞
8.4
8
*
0705A
ICD-9 Finland
Viral hepatitis, Other specified viral hepatitis without mention of hepatic coma
+∞
8.4
8
*
F19.2
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, dependence syndrome
+∞
8.4
8
*
F15.3
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, withdrawal state
+∞
8.4
8
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.4
8.2
33
112
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.1
8.1
18
39
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.9
8.1
26
76
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
47.3
7.8
9
*
A06AD11
ATC
lactulose; oral
3.6
7.7
28
89
F60.2
ICD-10 Finland
Dissocial personality disorder
83.8
7.5
8
*
K05.31
ICD-10 Finland
Periodontitis pronounced
3.5
7.4
28
91
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
+∞
7.3
7
*
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
+∞
7.3
7
*
N05BA02
ATC
chlordiazepoxide; systemic
10.8
7.2
13
13
R4110
NOMESCO Finland
Physiotherapy
2.6
7.1
55
268
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.8
6.9
15
21
F60.9
ICD-10 Finland
Personality disorder, unspecified
10.7
6.7
12
12
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
10.7
6.7
12
12
P01AB01
ATC
metronidazole; oral, rectal
2.4
6.6
79
466
Z3231
NOMESCO Finland
Registered nurse
2.5
6.6
52
254
Z71.8
ICD-10 Finland
Other specified counselling
2.4
6.6
60
315
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
6.4
32
124
F19.00
ICD-10 Finland
Intoxication caused by several drugs in combination or by other psychoactive substances uncomplicated
+∞
6.3
6
*
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
+∞
6.3
6
*
A46
ICD-10 Finland
Erysipelas
2.9
6.1
31
121

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
69
208
5.04
22.17
2.3
1.6
—
—
—
0
0
28
34
9.75
22.08
11.2
1.8
—
—
—
0
0
47
104
5.96
21.51
2.1
1.6
—
—
—
0
0
74
261
4.38
18.96
2.6
1.8
—
—
—
0
0
24
32
8.63
17.46
1.1
1.1
—
—
—
0
0
56
171
4.48
17.16
2.2
1.8
—
—
—
0
0
16
0
+∞
16.97
2.3
0.0
—
—
—
0
0
24
24
11.53
13.02
1.3
1.2
—
—
—
0
0
23
42
6.22
12.52
7.1
1.4
—
—
—
0
0
24
50
5.46
11.37
1.5
1.4
170.50
269.19
miu/ml
—
8
32
72
329
3.14
11.33
9.6
7.2
—
—
—
0
0
21
24
9.88
10.66
1.0
1.1
—
—
—
0
0
24
53
5.14
10.64
7.4
1.5
—
—
—
0
0
24
57
4.77
9.76
7.5
1.5
—
—
—
0
0
24
57
4.77
9.76
7.5
1.5
—
—
—
0
0
24
57
4.77
9.76
7.5
1.5
—
—
—
0
0
20
26
8.61
9.47
7.9
1.6
—
—
—
0
0
9
0
+∞
9.46
1.0
0.0
—
—
—
0
0
79
416
2.75
9.15
2.3
1.9
95.18
92.68
pmol/l
0.21
45
238
100
598
2.76
8.93
9.4
6.0
0.68
0.71
%
0.21
94
560
23
57
4.54
8.86
7.7
1.5
—
—
—
0
0
97
582
2.66
8.44
12.1
8.9
0.00
0.00
e9/l
0.49
82
477
101
620
2.67
8.36
9.4
6.0
3.10
2.85
%
0.54
96
585
11
5
23.43
8.13
1.1
1.0
—
—
—
0
0
104
662
2.59
7.76
9.5
6.2
0.04
0.04
e9/l
0.21
89
588
106
681
2.61
7.76
9.7
6.5
0.19
0.19
e9/l
0.06
90
614
104
663
2.59
7.72
9.5
6.2
0.57
0.56
e9/l
0.24
89
587
11
6
19.51
7.71
1.1
1.0
—
—
—
0
0
106
683
2.60
7.68
9.3
6.2
1.83
1.96
e9/l
0.33
91
620
18
41
4.81
7.64
1.2
1.2
—
—
—
0
0
67
363
2.44
6.89
3.3
2.2
—
—
—
0
0
112
771
2.47
6.58
14.9
10.2
3.69
4.02
e9/l
1.11
100
682
10
7
15.11
6.48
5.5
1.1
—
—
—
0
0
18
47
4.18
6.46
1.7
1.3
—
—
—
0
0
83
517
2.24
5.96
6.1
5.9
1.22
1.21
mmol/l
0.22
78
480
39
177
2.58
5.72
4.1
2.5
1.69
2.25
e6/l
0.23
19
95
64
364
2.25
5.68
4.7
4.4
7.40
7.40
ph
—
6
69
132
1011
2.65
5.67
11.9
7.9
88.68
76.29
u/l
1.03
126
953
51
266
2.34
5.53
2.9
3.4
—
—
—
0
0
94
630
2.17
5.47
9.6
6.5
—
—
—
0
0
27
104
2.92
5.39
7.1
6.2
—
—
—
0
0
81
516
2.14
5.33
12.6
11.8
1.19
1.18
inr
0.02
20
157
55
305
2.22
5.10
7.6
4.3
—
—
—
0
0
78
497
2.10
5.06
5.5
3.2
5.65
5.84
ph
—
7
52
67
408
2.10
4.86
5.0
3.4
13.25
22.13
e6/l
0.76
43
288
36
170
2.44
4.81
2.1
2.2
—
—
—
0
0
56
323
2.12
4.65
4.5
2.5
—
—
—
0
0
27
113
2.67
4.61
4.0
4.1
—
—
—
0
0
56
326
2.10
4.52
4.4
2.7
0.18
0.55
e6/l
1.07
38
240
46
250
2.17
4.41
3.2
2.0
2.98
3.21
mg/l
0.24
40
213
83
563
1.97
4.34
6.9
7.1
1.21
1.22
mmol/l
0.11
73
484
60
369
1.99
4.11
6.9
3.0
7.26
8.26
mmol/l
0.88
54
325
31
148
2.35
4.02
3.8
6.5
104.71
104.09
mmol/l
0.41
31
148
58
355
1.99
4.01
4.4
2.9
22.93
201.89
e6/l
0.49
41
272
103
765
1.95
4.00
4.6
3.8
—
291.00
—
0
12
48
276
2.05
3.94
1.9
1.6
1.15
0.98
mg/l
0.28
40
217
153
1359
3.26
3.90
21.2
13.3
139.17
139.72
mmol/l
2.50
148
1330
99
734
1.90
3.77
5.7
4.5
6.99
6.64
mmol/l
0.39
94
688
153
1365
3.17
3.74
21.7
13.4
3.98
3.98
mmol/l
0.03
148
1333
11
25
4.64
3.70
4.3
2.2
16.56
5.08
u/ml
0.41
11
25
15
51
3.14
3.68
7.3
7.5
24.20
24.40
mmol/l
0.09
15
51
29
140
2.31
3.66
1.9
1.6
—
—
—
0
0
8
14
5.95
3.38
2.0
1.9
29.45
35.00
%
—
8
14
60
393
1.84
3.28
3.9
3.5
2.31
2.35
mmol/l
1.31
52
355
42
246
1.95
3.22
1.7
1.5
18.27
20.65
nmol/l
0.50
35
209
17
69
2.64
3.07
1.2
1.1
—
—
—
0
0
25
127
2.15
2.79
3.2
1.7
—
—
—
0
0
31
172
1.99
2.75
1.2
1.2
—
—
—
0
0
32
180
1.97
2.73
2.1
1.7
1044.28
1328.09
nmol/l
1.01
25
138
9
25
3.75
2.62
1.1
1.4
—
—
—
0
0
26
138
2.05
2.60
1.3
1.4
—
—
—
0
0
16
69
2.46
2.58
2.4
2.4
167.62
84.28
ng/l
0.52
16
60
82
619
1.66
2.57
3.2
3.3
0.00
0.01
estimate
—
10
124
5
7
7.32
2.56
1.0
1.6
—
—
—
0
0
33
193
1.89
2.51
3.5
2.6
2.47
2.44
mmol/l
0.66
26
172
36
219
1.83
2.43
5.7
3.2
214.73
133.45
ng/l
0.21
31
146
45
294
1.73
2.39
1.3
1.4
2.65
2.56
g/l
0.11
30
195
82
627
1.62
2.39
3.3
3.3
0.00
0.00
estimate
—
9
111
81
619
1.62
2.35
4.9
4.4
0.00
0.00
estimate
—
10
119
104
852
1.62
2.21
4.3
3.7
—
—
—
0
0
10
36
2.89
2.18
3.6
2.8
—
—
—
0
0
11
43
2.67
2.12
1.5
1.3
—
—
—
0
0
41
273
1.67
2.01
6.9
3.7
1.01
1.02
kg/l
—
5
36
9
200
0.42
2.01
1.1
1.4
—
—
—
0
0
110
933
1.56
1.85
4.1
3.4
—
—
—
0
0
134
1195
1.70
1.79
5.0
4.5
1.85
1.84
mu/l
0.03
125
1108
0
46
0.00
1.74
0.0
1.5
—
—
—
0
0
5
13
3.93
1.73
11.8
5.3
12.66
11.69
mg/l
—
5
13
154
1446
2.32
1.70
23.3
14.2
73.27
76.53
umol/l
0.90
154
1446
5
14
3.65
1.62
1.4
1.4
—
—
—
0
0
146
1347
1.85
1.54
20.5
12.4
24.13
22.26
mg/l
0.30
126
1026
30
198
1.63
1.52
1.1
1.4
224.00
436.44
titre
—
5
45
152
1426
2.07
1.43
16.2
11.4
—
—
—
0
0
111
976
1.44
1.31
3.9
3.8
12.17
10.01
mm/h
0.94
104
910
18
110
1.72
1.21
1.4
1.3
—
—
—
0
0
32
228
1.50
1.18
3.4
2.6
536.54
562.74
mosm/kgh2o
0.24
26
192
41
312
1.42
1.09
1.3
1.3
1.72
1.68
u/ml
0.01
14
95
12
67
1.85
1.08
7.6
4.5
24.95
24.84
mmol/l
0.03
12
67
33
243
1.45
1.04
3.4
2.6
8.84
8.20
e6/l
0.05
27
215
18
116
1.62
1.02
3.2
2.6
1.46
1.75
%
0.78
18
105
13
77
1.75
0.98
1.4
1.2
—
—
—
0
0
21
142
1.55
0.98
1.3
1.2
—
—
—
0
0
0
31
0.00
0.97
0.0
5.6
—
27.78
—
0
18
21
143
1.54
0.95
1.2
1.2
—
—
—
0
0
17
113
1.56
0.86
6.6
7.1
94.73
95.04
%
0.08
17
108
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
26
0.00
0.79
0.0
1.4
—
—
—
0
0
0
26
0.00
0.79
0.0
1.4
—
—
—
0
0
49
584
0.77
0.78
2.2
2.7
—
—
—
0
0
0
28
0.00
0.77
0.0
1.6
—
—
—
0
0
0
28
0.00
0.77
0.0
4.6
—
—
—
0
0
5
24
2.12
0.75
1.0
1.2
—
—
—
0
0
60
512
1.27
0.73
2.1
1.9
—
—
—
0
0
5
26
1.95
0.71
2.4
3.2
—
—
—
0
0
5
27
1.88
0.69
1.6
1.3
—
—
—
0
0
156
1518
1.75
0.64
30.9
18.2
40.07
40.97
%
1.03
150
1445
8
55
1.48
0.57
1.1
1.1
—
—
—
0
0
10
67
1.52
0.51
1.0
2.6
—
—
—
0
0
19
147
1.33
0.48
1.7
1.4
—
—
—
0
0
7
49
1.45
0.46
1.4
1.2
—
—
—
0
0
7
50
1.42
0.45
1.7
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
3.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
41
357
1.20
0.41
1.8
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
2.6
—
—
—
0
0
5
35
1.44
0.39
1.0
1.6
—
—
—
0
0
5
35
1.44
0.39
1.4
1.2
—
—
—
0
0
12
158
0.74
0.39
1.6
1.6
—
—
—
0
0
5
76
0.65
0.36
1.2
3.7
—
7.42
—
0
8
142
1379
1.24
0.34
4.8
4.5
2.74
2.86
mmol/l
0.74
133
1293
11
83
1.35
0.33
1.2
1.1
—
—
—
0
0
38
336
1.17
0.32
4.3
3.3
102.67
271.16
mg/l
0.39
27
222
12
93
1.31
0.31
1.4
1.5
—
—
—
0
0
12
93
1.31
0.31
2.1
4.4
—
—
—
0
0
7
55
1.28
0.30
1.9
2.1
—
—
—
0
0
7
56
1.26
0.30
1.4
3.5
—
—
—
0
0
9
117
0.76
0.28
1.9
1.4
—
—
—
0
0
134
1301
1.17
0.28
4.3
4.0
6.17
5.90
mmol/l
0.82
125
1209
12
95
1.28
0.27
2.3
3.8
—
—
—
0
0
10
77
1.32
0.27
2.3
3.6
122.80
129.84
g/l
—
10
77
35
315
1.14
0.24
2.3
3.3
—
—
—
0
0
7
95
0.73
0.23
1.3
1.8
—
—
—
0
0
39
355
1.13
0.23
5.3
3.8
14.04
11.93
mg/mmol
0.14
28
228
129
1322
0.88
0.21
3.9
3.7
1.45
1.31
mmol/l
1.00
123
1234
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
74.73
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
222.05
—
0
10
0
13
0.00
0.21
0.0
1.5
—
33.69
—
0
13
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
9
112
0.79
0.20
1.1
1.2
—
17.94
—
0
8
6
49
1.23
0.20
2.0
1.5
—
—
—
0
0
37
340
1.11
0.18
3.5
3.5
0.00
0.03
estimate
—
8
111
126
1230
1.11
0.18
5.7
5.2
38.87
39.43
mmol/mol
0.27
121
1168
27
246
1.12
0.15
1.3
1.2
75.97
34.13
iu/ml
—
6
79
9
80
1.13
0.15
1.9
1.8
—
—
—
0
0
9
80
1.13
0.15
4.4
4.0
4.70
4.66
pmol/l
—
9
68
29
268
1.10
0.13
2.2
2.8
0.55
0.72
ug/l
0.57
18
156
16
179
0.88
0.13
1.4
1.4
—
—
—
0
0
12
105
1.15
0.11
4.6
3.0
—
—
—
0
0
35
370
0.93
0.10
3.3
2.9
—
—
—
0
0
5
44
1.14
0.10
2.6
1.8
—
59.92
—
0
12
14
126
1.12
0.09
1.7
2.1
366.07
372.66
nmol/l
0.04
14
114
6
53
1.14
0.09
4.2
5.5
—
—
—
0
0
7
64
1.10
0.08
2.1
4.0
25.99
24.54
mmol/l
—
7
64
6
70
0.85
0.08
3.2
2.8
2.10
1.38
%
—
6
70
8
75
1.07
0.07
2.4
4.8
—
—
—
0
0
138
1365
1.07
0.07
4.3
4.1
4.62
4.74
mmol/l
0.58
129
1290
12
108
1.12
0.07
1.2
1.2
—
—
—
0
0
11
122
0.89
0.07
2.2
2.2
—
6.75
—
0
8
30
290
1.04
0.03
4.2
2.5
—
—
—
0
0
137
1362
1.04
0.02
4.3
4.1
1.33
1.45
mmol/l
2.48
129
1276
44
448
0.98
0.01
3.2
3.5
12.81
32.01
ng/l
2.44
21
276
24
239
1.00
0.00
1.4
1.2
31.04
11.73
u/ml
—
5
96
45
452
0.99
0.00
3.4
4.3
1.48
2.49
ug/l
0.75
36
411
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
7.75
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
8.20
—
0
5
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
5.58
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
985.14
—
0
7
0
7
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
2.87
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.87
-0.00
1.0
4.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
12.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
52.50
—
0
7
8
84
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
167.61
—
0
6
0
7
0.00
-0.00
0.0
11.4
—
—
—
0
0
6
68
0.88
-0.00
3.2
2.9
0.65
0.67
%
—
6
68
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
0.85
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
2456.43
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_HEPATITIS_B and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
AB1_HEPATITIS_B 3.56 [2.5, 5.06] < 0.001
Birth year 0.986 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 128 out of 555 males with AB1_HEPATITIS_B died.

Mortality risk

Mortality risk for people of age

years, who have AB1_HEPATITIS_B.

N-year risk Females Males
1 No data 0.522%
5 No data 4.322%
10 No data 10.091%
15 No data 17.924%
20 No data 29.368%

Relationships between endpoints

Index endpoint: AB1_HEPATITIS_B – Acute hepatitis B

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data