Other disorders of white blood cells

D3_OTHERWHITECELL

Hypereosinophilic syndrome: The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D72
  • Cause of death: ICD-10 D72

2 out of 7 registries used, show all original rules.

2037

4. Check minimum number of events

None

2037

5. Include endpoints

2158

6. Filter based on genotype QC (FinnGen only)

2060

Control definitions (FinnGen only)

Control exclude
D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D70-D77
Name in latin
Aliae morbositates leucocytorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15172 7959 7095
Only index persons 12791 6804 5987
Unadjusted period prevalence (%)
Whole population 0.21 0.23 0.20
Only index persons 0.24 0.25 0.23
Median age at first event (years)
Whole population 58.28 57.40 59.16
Only index persons 56.26 54.92 57.78

-FinnGen-

Key figures

All Female Male
Number of individuals 2060 1107 953
Unadjusted period prevalence (%) 0.41 0.39 0.44
Median age at first event (years) 57.15 52.74 62.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2158
Matched controls
21580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D72.1
ICD-10 Finland
Eosinophilia
3718.7
307.7
580
*
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
335.1
307.7
315
11
XW000
NOMESCO Finland
Bone marrow biopsy
24.3
307.7
605
340
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
46.6
307.7
252
61
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
12.3
307.7
372
360
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
2129.5
307.7
1213
13
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
53.6
277.9
159
32
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
27.9
213.6
146
56
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.3
173.9
565
1651
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
63.9
144.7
80
13
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
113.4
1271
7381
L01XX05
ATC
hydroxycarbamide; oral
14.1
103.7
96
71
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
31.9
95.3
62
20
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.0
92.9
216
474
189
Kela drug reimbursment
Imatinib
39.0
92.8
57
15
D70.89
ICD-10 Finland
Neutropenic splenomegaly
114.0
90.7
98
9
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
33.1
90.2
58
18
R50.9
ICD-10 Finland
Fever, unspecified
3.0
88.4
492
1951
2888B
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOPENIA]
+∞
81.8
78
*
H02AB06
ATC
prednisolone; systemic
2.3
80.7
1205
7551
L01XE01
ATC
[U] imatinib
40.9
79.0
48
12
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
41.8
74.4
45
11
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
70.2
693
3588
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
68.9
351
1311
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
13.1
67.6
65
51
M04AA01
ATC
allopurinol; systemic
2.8
66.2
401
1643
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
7.5
63.0
92
128
L03AA02
ATC
filgrastim; parenteral
5.5
61.4
122
232
WW500
NOMESCO Finland
Blood transfusion
4.5
57.4
148
351
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
56.6
284
1046
H02AB09
ATC
hydrocortisone; systemic
5.6
56.4
109
202
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
56.4
210
647
JN4BD
NOMESCO Finland
Extensive body CT
2.8
56.2
310
1202
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
56.1
805
4764
J32.4
ICD-10 Finland
Chronic pansinusitis
7.2
56.1
84
120
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.9
55.6
295
1120
J01MA12
ATC
levofloxacin; systemic
2.3
53.7
500
2485
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
53.0
499
2490
TGC00
NOMESCO Finland
Bronchial lavation
5.2
50.7
106
211
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
15.6
49.5
43
28
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.4
49.4
187
581
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.0
47.9
237
863
R03BB04
ATC
tiotropium bromide; inhalant
2.6
47.7
300
1240
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
10.2
47.0
53
53
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
15.7
46.1
40
26
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
43.5
291
1237
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.2
42.4
117
292
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
42.3
703
4294
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
40.8
39
*
A02BC02
ATC
pantoprazole; systemic
1.9
40.3
1494
11687
127
Kela drug reimbursment
Transplant complication
6.3
40.0
68
111
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
76.7
40.0
45
6
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.8
39.7
215
820
J45.1
ICD-10 Finland
Nonallergic asthma
2.8
39.7
210
791
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.5
39.7
272
1167
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.5
39.4
141
422
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
38.8
212
812
ZXE00
NOMESCO Finland
One hour or less
1.8
38.2
895
6053
C91.7
ICD-10 Finland
Other lymphoid leukaemia
135.8
37.8
40
*
R03DC03
ATC
montelukast; oral
2.1
37.7
402
2081
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.2
37.6
102
251
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
37.2
1152
8436
J01MA14
ATC
moxifloxacin; systemic
2.5
37.2
247
1043
C03CA01
ATC
furosemide; systemic
1.9
37.2
688
4317
ZX112
NOMESCO Finland
Subcutaneous
4.9
37.1
82
171
R03AK08
ATC
formoterol and beclometasone; inhalant
3.4
37.1
139
428
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
69.5
36.1
41
6
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
35.4
412
2201
WW200
NOMESCO Finland
Immunization
4.2
35.2
95
233
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.6
35.2
118
338
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
67.8
35.1
40
6
ZX120
NOMESCO Finland
Intravenous
2.5
35.0
250
1091
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.0
34.6
476
2698
JN4AD
NOMESCO Finland
Body CT examination
2.4
34.5
263
1182
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
50.9
33.5
40
8
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
33.2
517
3051
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
75.4
32.9
37
5
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.2
32.4
89
221
Z3231
NOMESCO Finland
Registered nurse
1.8
32.3
622
3920
J01DB01
ATC
cefalexin; oral
2.0
31.8
1784
15227
A04AA01
ATC
ondansetron; systemic, rectal
2.5
30.9
205
863
R03AC02
ATC
salbutamol; inhalant
1.7
30.7
1178
8962
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
4.1
30.6
85
213
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.9
30.5
146
520
L01EA01
ATC
imatinib; oral
52.2
30.4
36
7
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.4
30.3
231
1036
Z2221
NOMESCO Finland
Medical doctor
1.8
29.7
619
3977
H02AB07
ATC
prednisone; oral
2.1
29.4
326
1702
A41.9
ICD-10 Finland
Sepsis, unspecified
3.4
29.2
107
325
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
5.7
28.9
54
97
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
28.6
793
5505
JN6AD
NOMESCO Finland
CT of torso and neck
5.4
28.6
56
105
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
28.5
430
2497
GD1AD
NOMESCO Finland
Thorax CT examination
2.7
28.3
158
610
D72.0
ICD-10 Finland
Genetic anomalies of leukocytes
+∞
28.2
27
*
L04AA06
ATC
mycophenolic acid; systemic
4.7
27.9
64
138
A05AA02
ATC
ursodeoxycholic acid; oral
5.0
27.5
59
120
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
27.2
249
1204
L04AD01
ATC
ciclosporin; systemic
4.7
27.2
63
137
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
10.5
27.1
30
29
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
26.4
508
3171
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
26.4
505
3149
XG474
NOMESCO Finland
Exhalation nntrogen oxide
3.7
26.4
85
237
316
Kela drug reimbursment
Imatinib
52.4
26.2
31
6
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
37.2
26.2
33
9
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
26.0
576
3743
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
25.8
761
5336
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.5
25.3
90
268
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
25.2
519
3300
A02BC01
ATC
omeprazole; systemic
1.7
24.7
586
3872
R06.0
ICD-10 Finland
Dyspnoea
1.7
24.6
589
3900
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
24.0
389
2299
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
24.0
240
1201
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.4
23.8
169
733
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
23.7
235
1171
B73
ICPC
Leukaemia
41.9
23.6
29
7
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
23.6
156
654
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
23.6
412
2490
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
23.5
385
2283
R4110
NOMESCO Finland
Physiotherapy
1.7
22.9
592
3988
E0000UV, ,
ATC
1.6
22.4
858
6355
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
22.4
133
530
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.2
21.8
90
294
ZX108
NOMESCO Finland
Inhalation
7.5
21.7
31
42
H02AB04
ATC
methylprednisolone; systemic
1.9
21.6
314
1788
D45
ICD-10 Finland
Polycythaemia vera
6.2
21.6
37
61
R03BA08
ATC
ciclesonide; inhalant
2.2
21.4
199
966
R06AE07
ATC
cetirizine; oral
1.6
21.2
880
6615
UJF32
NOMESCO Finland
Coloscopy
1.7
21.1
549
3694
J01AA02
ATC
doxycycline; systemic
1.6
21.0
1606
13830
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
21.0
352
2096
D75.2
ICD-10 Finland
Essential thrombocytosis
60.6
20.9
24
*
L04AX01
ATC
azathioprine; systemic
2.8
20.7
106
391
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
20.7
456
2934
J01FF01
ATC
clindamycin; systemic
1.6
20.6
570
3889
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.2
20.5
82
263
A46
ICD-10 Finland
Erysipelas
1.8
20.4
318
1850
Z3226
NOMESCO Finland
Physiotherapist
1.7
20.4
399
2484
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
20.3
315
1829
R03BA05
ATC
fluticasone; inhalant
1.8
20.3
388
2399
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
20.2
165
760
J46
ICD-10 Finland
Status asthmaticus
3.4
20.2
72
215
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
20.0
143
622
A07AA02
ATC
nystatin; oral
2.4
19.9
139
598
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.6
19.9
118
470
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
19.8
248
1343
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
19.7
208
1059
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.8
19.7
60
161
L01BB05
ATC
fludarabine; systemic
40.5
19.5
24
6
L04AX03
ATC
methotrexate; systemic
2.0
19.5
216
1120
R05
ICD-10 Finland
Cough
1.7
19.4
443
2871
J45.8
ICD-10 Finland
Mixed asthma
3.1
19.3
82
273
Z2446
NOMESCO Finland
Social worker
2.2
19.2
160
743
B03XA02
ATC
darbepoetin alfa; parenteral
3.5
18.9
64
185
R53
ICD-10 Finland
Malaise and fatigue
1.6
18.8
492
3301
212
Kela drug reimbursment
Gout
3.8
18.7
57
153
3028
Kela drug reimbursment
Mepolizumab
70.5
18.7
21
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
18.7
221
1172
L01XX52
ATC
venetoclax; oral
23.9
18.6
26
11
N02AX02
ATC
tramadol; systemic, rectal
1.5
18.6
877
6721
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
18.4
246
1361
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.5
18.3
64
189
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
18.2
938
7310
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
7.2
18.2
27
38
J05AB11
ATC
valaciclovir; oral
1.8
18.2
302
1789
D07AB08
ATC
desonide; topical
1.9
18.0
231
1261
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
6.7
17.9
28
42
XQ800
NOMESCO Finland
Prick test
2.2
17.9
160
765
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
26.9
17.8
24
9
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
13.8
17.8
30
22
399
Kela drug reimbursment
Venetoclax
20.2
17.7
26
13
297, ,
Kela drug reimbursment
67.2
17.7
20
*
R03DX09
ATC
mepolizumab; parenteral
67.2
17.7
20
*
2883X
ICD-9 Finland
Diseases of white blood cells, Eosinophilia[EOSINOPHILIA, NUD]
+∞
17.7
17
*
2888A
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOSIS]
+∞
17.7
17
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
17.7
235
1296
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
17.6
339
2093
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.6
17.5
41
90
N05CF01
ATC
zopiclone; oral
1.5
17.5
645
4676
J01MA02
ATC
ciprofloxacin; systemic
1.5
17.4
793
6013
1512
Kela drug reimbursment
Ibrutinib
24.2
17.3
24
10
390
Kela drug reimbursment
Ibrutinib
24.2
17.3
24
10
R01AD08
ATC
fluticasone; nasal
1.6
17.2
563
3973
D07AC01
ATC
betamethasone; topical
1.5
17.2
723
5388
WX402
NOMESCO Finland
General anaesthesia
1.6
17.1
430
2847
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
17.1
403
2627
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
5.0
16.9
36
73
L01AA02
ATC
chlorambucil; oral
19.4
16.9
25
13
152
Kela drug reimbursment
Nilotinib
63.8
16.7
19
*
J01CA04
ATC
amoxicillin; systemic
1.6
16.7
1686
14963
L04AA01
ATC
[U] ciclosporin
4.5
16.6
40
90
DPA30
NOMESCO Finland
Sphenotomy
6.2
16.4
28
46
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
16.4
87
328
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.0
16.3
73
251
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
16.2
727
5476
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.6
16.1
92
360
J45
ICD-10 Finland
Asthma
1.9
16.1
215
1188
L01EL01
ATC
ibrutinib; oral
47.9
16.0
19
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.5
16.0
54
156
B03XA01
ATC
erythropoietin; parenteral
5.4
15.9
31
58
ZXD05
NOMESCO Finland
Urgent procedure
1.5
15.7
619
4531
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.3
15.7
40
94
R02
ICPC
Shortness of breath/dyspnoea
1.8
15.7
270
1612
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
15.7
413
2761
A02BC05
ATC
esomeprazole; systemic
1.5
15.5
802
6199
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
15.5
833
6486
XF600
NOMESCO Finland
Bloodpressure measurement
2.1
15.4
143
693
J01FA10
ATC
azithromycin; systemic
1.4
15.4
1123
9258
M05BA04
ATC
alendronic acid; oral
2.0
15.4
174
908
SPAT1263
SPAT
Sampling
1.5
15.3
834
6506
WX892
NOMESCO Finland
Monitored bed care
2.0
15.3
174
909
R03AK11
ATC
formoterol and fluticasone; inhalant
3.0
15.2
67
228
J02AC03
ATC
voriconazole; systemic
17.9
15.1
23
13
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
15.1
182
971
J01FA09
ATC
clarithromycin; systemic
1.5
15.1
613
4512
WZC30
NOMESCO Finland
Teaching
1.7
15.0
325
2067
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
14.8
577
4205
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.2
14.8
128
603
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
57.1
14.8
17
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
14.7
266
1610
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
14.6
135
654
AA1AD
NOMESCO Finland
CT of head and brain
1.5
14.6
545
3937
SPAT1254
SPAT
Administration of medicine
1.7
14.3
301
1899
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
19.3
14.2
21
11
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
22.4
14.2
20
9
P01AB01
ATC
metronidazole; oral, rectal
1.4
14.1
772
6004
XG410
NOMESCO Finland
Flow-volume spirometry
2.4
14.1
93
390
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.1
13.9
59
197
C07AB07
ATC
bisoprolol; oral
1.4
13.8
966
7844
L01XX28
ATC
[U] imatinib
53.7
13.8
16
*
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
4.9
13.8
30
62
N05BA01
ATC
diazepam; systemic, rectal
1.7
13.7
262
1610
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
5.7
13.7
25
44
R05
ICPC
Cough
1.5
13.6
471
3341
SPAT1255
SPAT
Intravenous administration of medicine
2.0
13.6
147
755
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
13.6
136
679
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
13.6
281
1764
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
13.6
553
4058
ZY010
NOMESCO Finland
Hospital outpatient
2.2
13.6
111
512
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.6
13.5
78
307
UJF92
NOMESCO Finland
Capsular endoscopy
3.2
13.5
54
174
1518, ,
Kela drug reimbursment
16.3
13.4
21
13
DHB20
NOMESCO Finland
Polypectomy of internal nose
3.6
13.4
44
125
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
5.6
13.4
25
45
L04AD02
ATC
tacrolimus; systemic
4.6
13.3
31
68
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
9.7
13.2
26
27
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
13.2
872
6994
B01AB10
ATC
tinzaparin; parenteral
1.8
13.0
204
1183
R01AD09
ATC
mometasone; nasal
1.4
13.0
865
6944
D75.1
ICD-10 Finland
Secondary polycythaemia
28.5
13.0
17
6
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
4.7
12.8
29
62
N02AA05
ATC
oxycodone; systemic
1.6
12.8
348
2335
N03AX16
ATC
[U] pregabalin
1.5
12.8
452
3214
A03
ICPC
Fever
1.6
12.8
319
2099
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
12.7
271
1712
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.6
12.7
75
299
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
12.6
126
628
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
12.6
357
2417
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
4.8
12.6
28
59
150
Kela drug reimbursment
Dasatinib
70.3
12.6
14
*
328
Kela drug reimbursment
Nilotinib
70.3
12.6
14
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.2
12.5
111
529
SPAT1262
SPAT
Handing over of treatment supplies
1.6
12.5
349
2356
N02BE01
ATC
paracetamol; systemic, rectal
1.6
12.5
1824
16773
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.3
12.5
99
451
S97
ICPC
Chronic ulcer skin
2.0
12.5
129
652
ZXA10
NOMESCO Finland
Bilateral
1.6
12.4
360
2453
B01AA03
ATC
warfarin; systemic
1.6
12.4
366
2504
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
3.8
12.3
37
99
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
14.4
12.3
20
14
WX002
NOMESCO Finland
Sedation and analgesia
1.5
12.2
384
2661
N06AX16
ATC
venlafaxine; oral
1.6
12.2
273
1746
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
12.2
296
1932
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
37.8
12.2
15
*
R03AC12
ATC
salmeterol; inhalant
2.3
12.2
96
436
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.6
12.1
69
270
J33.8
ICD-10 Finland
Other polyp of sinus
2.9
12.1
55
191
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.9
12.1
55
191
R60.0
ICD-10 Finland
Localized oedema
1.7
12.1
239
1481
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
12.0
395
2765
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
12.0
165
920
N05BA04
ATC
oxazepam; oral
1.5
11.9
498
3661
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.1
11.9
112
547
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
11.9
1414
12432
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
11.8
264
1687
J02AC01
ATC
fluconazole; systemic
1.4
11.8
718
5647
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
11.8
118
589
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
4.3
11.7
30
71
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
11.7
158
876
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.1
11.7
104
497
R96
ICPC
Asthma
1.8
11.7
190
1115
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.9
11.6
54
190
RS220, ,
NOMESCO Finland
3.6
11.6
37
103
L01EA03
ATC
nilotinib; oral
65.3
11.6
13
*
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
65.3
11.6
13
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.4
11.6
80
343
Z88.6
ICD-10 Finland
Personal history of allergy to analgesic agent
19.0
11.6
17
9
9101
FHL
Bone biopsy
23.0
11.6
16
7
120
Kela drug reimbursment
Hypogammaglobulinaemia
23.0
11.6
16
7
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
11.5
94
433
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
4.0
11.5
32
81
N03AE01
ATC
clonazepam; systemic
2.0
11.4
117
589
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
120.6
11.4
12
*
E000001, ,
ATC
1.5
11.4
377
2641
N06AB04
ATC
citalopram; systemic
1.5
11.3
393
2778
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
35.2
11.3
14
*
A06AD11
ATC
lactulose; oral
1.6
11.2
285
1881
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.0
11.2
119
608
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
11.1
220
1364
UDC00
NOMESCO Finland
Ear microscopy
1.9
11.1
150
832
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.4
11.0
77
333
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
11.0
176
1028
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
14.0
11.0
18
13
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.3
11.0
40
122
N07BA03
ATC
varenicline; oral
2.2
11.0
93
436
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
10.9
251
1616
R01AD12
ATC
fluticasone furoate; nasal
1.4
10.9
579
4440
T78.4
ICD-10 Finland
Allergy, unspecified
2.2
10.9
88
405
N05AA02
ATC
levomepromazine; systemic
2.3
10.8
83
373
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
2.9
10.8
51
181
J47
ICD-10 Finland
Bronchiectasis
3.0
10.8
46
154
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
10.8
54
198
E000002, ,
ATC
1.7
10.8
210
1295
C03DA01
ATC
spironolactone; oral
1.6
10.7
233
1480
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.9
10.7
31
81
P01BA02
ATC
hydroxychloroquine; oral
1.8
10.6
158
902
L01XE06
ATC
[U] dasatinib
60.3
10.6
12
*
T90
ICPC
Diabetes non-insulin dependent
1.5
10.6
456
3361
L28
ICPC
Limited function/disability (L)
1.5
10.5
337
2340
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
10.5
803
6529
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
4.0
10.5
29
73
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.6
10.5
34
96
N05AH02
ATC
clozapine; systemic
3.2
10.4
41
131
J01FA06
ATC
roxithromycin; oral
1.4
10.4
757
6103
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2.3
10.4
77
341
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
10.4
259
1699
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.2
10.3
89
420
L01XE27
ATC
[U] ibrutinib
32.7
10.3
13
*
R11
ICD-10 Finland
Nausea and vomiting
1.8
10.3
165
964
D07AA02
ATC
hydrocortisone; topical
1.6
10.3
258
1696
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
10.6
10.3
19
18
A01AB09
ATC
miconazole; local oral
1.8
10.3
164
957
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.3
10.3
76
337
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
10.2
362
2567
L01AA01
ATC
cyclophosphamide; systemic
7.5
10.2
23
31
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.2
10.1
81
371
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
10.1
132
725
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.8
10.1
50
183
N06AX11
ATC
mirtazapine; oral
1.4
10.1
634
4991
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
11.3
10.0
18
16
R03BA02
ATC
budesonide; inhalant
1.5
10.0
336
2354
R03DC01
ATC
zafirlukast; oral
3.2
10.0
38
119
R4120
NOMESCO Finland
Occupational therapy
1.9
10.0
130
712
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.2
9.9
38
120
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
9.9
171
1021
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.3
9.9
71
311
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
2.8
9.8
49
180
J33.9
ICD-10 Finland
Nasal polyp, unspecified
3.6
9.8
32
91
1XC02, ,
NOMESCO Finland
4.5
9.8
23
51
B99
ICPC
Blood/lymph/spleen disease other
9.6
9.8
19
20
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
3.5
9.7
33
96
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
9.7
158
928
L01XE08
ATC
[U] nilotinib
55.2
9.6
11
*
J20
ICD-10 Finland
Acute bronchitis
1.7
9.6
191
1183
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.8
9.6
131
729
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
9.6
117
628
R4190
NOMESCO Finland
Nutritional therapy
2.2
9.6
79
367
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
9.6
137
774
Z51.5
ICD-10 Finland
Palliative care
1.8
9.5
148
856
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
15.1
9.5
15
10
R03BA01
ATC
beclometasone; inhalant
1.6
9.5
257
1718
R06.2
ICD-10 Finland
Wheezing
2.1
9.5
91
448
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.1
9.5
86
415
A28
ICPC
Limited function/disability NOS
1.5
9.4
316
2212
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
3.0
9.4
40
134
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
9.4
173
1050
R03DX10
ATC
benralizumab; systemic
30.1
9.4
12
*
395
Kela drug reimbursment
Dupilumab
17.6
9.4
14
8
D72
ICD-10 Finland
Other disorders of white blood cells
+∞
9.4
9
*
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
9.4
130
727
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
9.4
463
3492
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
9.3
208
1328
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
9.5
9.3
18
19
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
9.5
9.3
18
19
R03DA04
ATC
theophylline; systemic, rectal
2.0
9.2
101
522
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
9.2
449
3376
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
9.2
208
1332
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
9.2
160
957
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.8
9.2
44
158
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
9.2
185
1151
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.7
9.2
184
1144
A07EA06
ATC
budesonide; oral, local oral
2.3
9.2
70
315
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.3
9.1
64
278
N03AX09
ATC
lamotrigine; oral
2.0
9.1
90
449
R55
ICD-10 Finland
Syncope and collapse
1.6
9.1
210
1353
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
9.1
480
3661
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.8
9.0
131
743
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.6
9.0
199
1267
C95.9
ICD-10 Finland
Leukaemia, unspecified
36.8
9.0
11
*
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
36.8
9.0
11
*
D02AX
ATC
Other emollients and protectives
2.3
9.0
64
279
N05CD07
ATC
temazepam; oral
1.6
9.0
218
1420
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
9.0
125
700
B01AB05
ATC
enoxaparin; parenteral
1.4
8.9
585
4617
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
8.9
721
5876
N05AH04
ATC
quetiapine; oral
1.5
8.9
322
2288
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
4.3
8.9
22
51
N18.8
ICD-10 Finland
Other chronic renal failure
2.5
8.8
53
214
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.9
8.8
117
646
C83.1
ICD-10 Finland
Mantle cell lymphoma
8.6
8.8
18
21
A02BC03
ATC
lansoprazole; oral
1.4
8.8
534
4164
RD210, ,
NOMESCO Finland
2.9
8.8
40
140
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.2
8.7
69
315
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
8.7
222
1464
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
1.9
8.6
99
521
I51.4
ICD-10 Finland
Myocarditis, unspecified
4.6
8.6
20
44
D11AH05
ATC
dupilumab; topical
16.3
8.5
13
8
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
16.3
8.5
13
8
TAB00
NOMESCO Finland
Lumbar puncture
2.0
8.5
92
474
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.2
8.5
33
105
3027
Kela drug reimbursment
Benralizumab
27.6
8.5
11
*
SPAT1260
SPAT
Consultation of another employee
1.5
8.4
321
2303
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.5
8.4
49
195
D73.1
ICD-10 Finland
Hypersplenism
90.4
8.4
9
*
B84
ICPC
Unexplained abnormal white cells
90.4
8.4
9
*
D07AC13
ATC
mometasone; topical
1.4
8.4
532
4171
A10AB05
ATC
insulin aspart; parenteral
1.7
8.4
146
873
L29.9
ICD-10 Finland
Pruritus, unspecified
2.4
8.4
57
244
ZXA05
NOMESCO Finland
Left side
1.4
8.4
459
3517
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
8.4
562
4448
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
3.8
8.3
25
67
9831/3-C42.1
ICD-O-3
T-cell large granular lymphocytic leukemia of bone marrow
+∞
8.3
8
*
L50.0
ICD-10 Finland
Allergic urticaria
2.5
8.3
52
214
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.3
8.3
58
251
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
8.3
499
3879
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
8.3
146
876
J05AB01
ATC
aciclovir; systemic
1.4
8.3
398
2981
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
4.1
8.3
22
54
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.3
8.2
30
92
J01DA01
ATC
[U] cefalexin
1.3
8.2
1190
10479
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
4.2
8.2
21
50
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.8
8.2
39
140
TQW99
NOMESCO Finland
Other minor procedure on skin
1.9
8.1
101
546
D07AD01
ATC
clobetasol; topical
1.5
8.1
295
2097
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
2.7
8.1
41
152
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
17.2
8.1
12
7
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
8.0
249
1714
R03AC13
ATC
formoterol; inhalant
1.9
8.0
98
527
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
8.0
207
1369
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
4.1
8.0
21
51
L03
ICD-10 Finland
Cellulitis
3.9
8.0
23
60
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.4
8.0
343
2518
S18
ICPC
Laceration/cut
1.3
8.0
871
7379
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.9
7.9
104
572
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.6
7.9
168
1059
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.9
292
2081
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
7.9
114
646
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
4.4
7.9
19
43
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.9
320
2323
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.9
7.9
101
552
318
Kela drug reimbursment
Teriparatide
6.1
7.8
20
33
6BA02, ,
NOMESCO Finland
8.5
7.8
16
19
R51.80
ICD-10 Finland
Headache
1.5
7.8
277
1960
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
2.7
7.8
39
144
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.3
7.7
56
247
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
45.1
7.7
9
*
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
3.9
7.7
22
57
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
7.7
525
4157
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
4.3
7.7
19
44
X57
ICD-10 Finland
Unspecified privation
2.5
7.7
46
186
Z2445
NOMESCO Finland
Psychologist
2.0
7.7
76
380
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.0
7.7
78
394
R06AX22
ATC
ebastine; oral
1.5
7.6
297
2139
J94.8
ICD-10 Finland
Other specified pleural conditions
2.9
7.6
34
118
374
Kela drug reimbursment
Ruxolitinib
25.1
7.6
10
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
6.2
7.5
19
31
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.9
7.5
97
531
DHA10
NOMESCO Finland
Biopsy of cavity of nose
3.8
7.5
22
58
Z31.5
ICD-10 Finland
Genetic counselling
1.9
7.5
91
488
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.6
7.5
43
170
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
4.3
7.5
19
45
ED1AA
NOMESCO Finland
Mandibular X-ray examination
4.4
7.4
18
41
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
80.4
7.4
8
*
D69.4
ICD-10 Finland
Other primary thrombocytopenia
80.4
7.4
8
*
D68.8
ICD-10 Finland
Other specified coagulation defects
3.5
7.4
25
73
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
3.5
7.4
25
73
PJA10
NOMESCO Finland
Exploration of lymph nodes
3.2
7.4
28
88
L01BB02
ATC
mercaptopurine; oral
3.4
7.4
26
78
L01BA01
ATC
methotrexate; systemic
2.1
7.4
68
331
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.2
7.4
58
265
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
6.0
7.4
19
32
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
6.0
7.4
19
32
L03AA13
ATC
pegfilgrastim; parenteral
2.0
7.4
77
393
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.0
7.3
20
50
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.3
7.3
53
234
K59.1
ICD-10 Finland
Functional diarrhoea
1.8
7.3
102
573
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
7.3
102
573
D73.5
ICD-10 Finland
Infarction of spleen
+∞
7.3
7
*
2888X
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOPATHIA ALIA DEFINITA]
+∞
7.3
7
*
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
7.3
7
*
A41.8
ICD-10 Finland
Other specified sepsis
2.6
7.3
40
155
J96.0
ICD-10 Finland
Acute respiratory failure
3.1
7.3
29
94
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.3
406
3112
M10.9
ICD-10 Finland
Gout, unspecified
1.7
7.3
128
769
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
2.8
7.3
34
121
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
3.5
7.3
24
69
N05BA06
ATC
lorazepam; systemic, sublingual
1.8
7.3
96
530
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
7.3
151
948
N05AB03
ATC
perphenazine; systemic, rectal
2.1
7.3
65
313
Z94.0
ICD-10 Finland
Kidney transplant status
3.3
7.2
26
79
N05AF03
ATC
chlorprothixene; systemic
2.4
7.2
49
210
A01AB04
ATC
amphotericin B; local oral
1.9
7.2
85
453
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
2.8
7.2
34
122
C01CA24
ATC
epinephrine; parenteral
1.8
7.1
112
652
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
7.1
270
1934
XG405
NOMESCO Finland
Education on PEF monitoring
2.8
7.1
33
117
TPH00
NOMESCO Finland
Phlebotomy
6.6
7.1
17
26
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
2.2
7.1
57
263
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.3
7.1
49
212
L26
ICD-10 Finland
Exfoliative dermatitis
12.1
7.1
12
10
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.1
7.1
63
303
H05AA02
ATC
teriparatide; parenteral
6.0
7.1
18
30
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.2
7.1
58
270
J12.8
ICD-10 Finland
Other viral pneumonia
3.6
7.0
22
61
3AC01, ,
NOMESCO Finland
3.2
7.0
26
81
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.4
6.9
44
183
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
2.5
6.9
42
171
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
2.5
6.9
42
171
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.0
6.9
70
353
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
6.9
148
936
Z49.1
ICD-10 Finland
Extracorporeal dialysis
2.9
6.9
31
108
R06AX27
ATC
desloratadine; oral
1.3
6.9
494
3932
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.1
6.9
28
92
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
4.0
6.9
19
48
C08CA01
ATC
amlodipine; oral
1.3
6.9
702
5864
R03AC03
ATC
terbutaline; inhalant
1.5
6.9
245
1734
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
2.6
6.9
38
148
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
2.7
6.9
34
125
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
3.1
6.9
27
87
TQW80
NOMESCO Finland
Local dermatologic skincare
2.3
6.9
51
228
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.8
6.9
105
607
B01AB04
ATC
dalteparin; parenteral
1.8
6.8
95
533
B02.9
ICD-10 Finland
Zoster without complication
1.7
6.8
119
713
D86.0
ICD-10 Finland
Sarcoidosis of lung
3.2
6.8
26
82
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.8
6.8
91
504
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
3.3
6.8
25
77
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
6.8
115
683
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
6.8
64
314
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
6.8
145
918
324
Kela drug reimbursment
Dasatinib
40.2
6.8
8
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.2
6.7
54
249
S21
ICPC
Skin texture symptom/complaint
1.5
6.7
252
1801
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
6.7
182
1217
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.2
6.7
53
243
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
6.7
491
3918
E000003, ,
ATC
1.9
6.7
80
428
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.4
6.7
23
68
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.7
6.7
125
764
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.7
6.7
114
680
N03AX12
ATC
[U] gabapentin; oral
1.4
6.7
295
2173
I42.3
ICD-10 Finland
Endomyocardial (eosinophilic) disease
22.6
6.7
9
*
251, ,
Kela drug reimbursment
22.6
6.7
9
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.5
6.7
194
1318
J42
ICD-10 Finland
Unspecified chronic bronchitis
3.0
6.7
28
94
R52.9
ICD-10 Finland
Pain, unspecified
1.6
6.7
171
1130
N06AX21
ATC
duloxetine; oral
1.5
6.7
204
1401
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
4.0
6.6
18
45
N03AX18
ATC
lacosamide; systemic
4.0
6.6
18
45
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.6
6.6
167
1099
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
7.8
6.6
14
18
D02AE01
ATC
carbamide; topical
1.7
6.6
114
682
D11AH01
ATC
tacrolimus; topical
3.6
6.6
21
59
B74
ICPC
Malignant neoplasm blood other
12.3
6.6
11
9
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
3.3
6.6
24
74
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.5
142
902
SPAT1281
SPAT
Other administrative function
1.6
6.5
144
918
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
6.5
125
769
9109
FHL
Other measure in this category
10.0
6.5
12
12
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.5
289
2130
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
2.7
6.5
33
123
R06AE09
ATC
levocetirizine; oral
1.4
6.5
246
1761
SPAT1104
SPAT
Monitoring of emergency patient
1.7
6.5
117
708
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
2.1
6.5
57
273
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
6.5
559
4561
R03AK03
ATC
[U] fenoterol and ipratropium bromide
1.8
6.5
91
513
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
3.7
6.5
20
55
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
6.5
467
3718
M81.4
ICD-10 Finland
Drug-induced osteoporosis
6.2
6.5
16
26
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
5.3
6.5
18
34
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.4
405
3160
C91
ICD-10 Finland
Lymphoid leukaemia
70.1
6.4
7
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
2.8
6.4
30
107
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.6
6.4
134
843
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
6.4
766
6514
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.4
1135
10110
UDM02
NOMESCO Finland
Sinoscopy
2.4
6.4
43
184
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
14.3
6.4
10
7
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
3.0
6.4
27
91
F20.9
ICD-10 Finland
Schizophrenia, unspecified
2.4
6.4
41
172
TKC20
NOMESCO Finland
Catheterisation of bladder
1.7
6.3
123
760
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.3
407
3185
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
2.7
6.3
33
125
A11CC03
ATC
alfacalcidol; systemic
2.2
6.3
48
217
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
6.0
6.3
16
27
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.4
6.3
40
167
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.0
6.3
61
304
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.1
6.3
57
277
174
Kela drug reimbursment
Ruxolitinib
18.1
6.3
9
5
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.3
1018
8970
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
6.3
6
*
D73.0
ICD-10 Finland
Hyposplenism
+∞
6.3
6
*
C91.5
ICD-10 Finland
Adult T-cell lymphoma/leukaemia [HTLV-1-associated]
+∞
6.3
6
*
2889X
ICD-9 Finland
Diseases of white blood cells, Unspecified disease of white blood cells
+∞
6.3
6
*
D70
ICD-10 Finland
Agranulocytosis
+∞
6.3
6
*
C09CA06
ATC
candesartan; oral
1.3
6.2
409
3209
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
3.0
6.2
26
87
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.0
6.2
26
87
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.6
6.2
124
771
C91.4
ICD-10 Finland
Hairy-cell leukaemia
26.7
6.2
8
*
L01XX35
ATC
anagrelide; oral
26.7
6.2
8
*
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
2.5
6.2
38
156
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
2.5
6.2
37
150
R78
ICPC
Acute bronchitis/bronchiolitis
2.3
6.2
43
187
TK800
NOMESCO Finland
Hemodialysis
2.3
6.2
42
181
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.3
6.2
42
181
E66.8
ICD-10 Finland
Other obesity
1.8
6.2
93
536
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
3.5
6.2
20
57
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
3.5
6.2
20
57
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
6.1
177
1200
A10AE04
ATC
insulin glargine; parenteral
1.5
6.1
172
1159
L28
ICD-10 Finland
Lichen simplex chronicus and prurigo
3.4
6.1
21
62
R5140
NOMESCO Finland
Monitoring the use of the aid
1.5
6.1
189
1300
R06.4
ICD-10 Finland
Hyperventilation
2.8
6.1
30
110
GEA00
NOMESCO Finland
Mediastinoscopy
7.7
6.1
13
17
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.3
6.1
43
188
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
6.1
520
4233
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
4.1
6.1
16
39
H50.1
ICD-10 Finland
Divergent concomitant strabismus
4.1
6.1
16
39
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
12.6
6.1
10
8
SPAT1079
SPAT
Echocardiography
3.0
6.1
25
83
K29.7
ICD-10 Finland
Gastritis, unspecified
2.0
6.1
62
315
R81
ICPC
Pneumonia
2.0
6.0
66
343
Z22.3
ICD-10 Finland
Carrier of other specified bacterial diseases
10.0
6.0
11
11
SAA04
NOMESCO Finland
Special examination of mouth
1.7
6.0
101
600
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.8
6.0
86
488
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
1.8
6.0
80
444
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
6.0
335
2564
R04.2
ICD-10 Finland
Haemoptysis
2.0
6.0
64
330

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
640
1299
6.58
318.31
3.7
2.7
9.67
10.70
g/l
5.19
585
1188
792
1963
5.79
317.52
4.9
2.5
1.77
1.80
%
0.32
741
1748
281
150
21.39
307.65
1.2
1.2
—
—
—
0
0
280
150
21.30
307.65
1.3
1.3
—
—
—
0
0
358
247
17.18
307.65
1.8
1.5
—
—
—
0
0
642
1453
5.87
281.50
5.3
2.5
70.93
69.76
e9/l
0.29
496
1106
1668
8269
5.48
267.20
15.7
6.1
8.37
8.62
%
1.52
1612
7745
1664
8234
5.46
267.18
14.9
5.8
3.64
2.85
%
9.61
1610
7696
1632
7982
5.29
265.21
14.7
5.8
0.67
0.67
%
0.10
1578
7450
1664
8277
5.41
264.14
17.4
6.1
—
—
—
0
0
1683
8497
5.46
260.63
15.1
5.9
33.27
27.70
%
27.34
1621
7986
515
1020
6.32
258.92
2.1
1.8
1.42
1.44
g/l
0.03
461
941
598
1393
5.56
251.52
8.1
3.9
0.75
0.88
%
0.62
388
465
1647
8380
5.08
246.68
13.8
5.7
51.06
57.37
%
39.14
1586
7863
555
1269
5.54
237.35
8.0
3.7
0.45
0.67
%
1.90
358
402
1671
8816
4.97
232.44
13.4
5.7
0.06
0.04
e9/l
1.43
1530
7616
1665
8801
4.90
229.91
13.5
5.6
0.71
0.58
e9/l
8.90
1520
7606
1692
9118
4.96
225.81
15.1
5.9
0.30
0.19
e9/l
24.86
1561
7986
555
1328
5.28
224.29
8.3
3.9
0.11
0.10
%
0.06
345
400
1680
9052
4.86
222.98
13.7
5.7
4.63
1.94
e9/l
13.78
1572
8007
525
1247
5.24
213.21
8.1
4.0
0.30
0.58
%
0.32
318
325
186
144
14.04
196.81
1.2
1.1
—
—
—
0
0
231
257
9.95
192.03
5.9
2.8
0.89
1.31
%
0.94
215
233
180
141
13.84
189.05
3.2
2.4
1.69
1.13
e9/l
0.50
156
132
1718
10230
4.33
178.02
19.5
8.5
4.49
4.13
e9/l
4.00
1607
8922
356
734
5.61
167.65
1.5
1.4
2.92
14.04
u/ml
—
8
19
455
1173
4.65
164.32
2.2
2.6
—
—
—
0
0
507
1430
4.33
162.78
2.3
2.9
66.10
66.40
g/l
0.34
468
1311
418
1062
4.64
153.11
2.3
1.3
514.99
216.93
u/ml
2.47
390
986
1518
9105
3.25
137.80
9.8
6.0
10.33
11.54
umol/l
6.82
1475
8640
131
107
12.97
133.65
3.4
2.5
819.17
500.89
e6/l
0.51
103
96
285
587
5.44
133.24
1.9
1.5
254.67
163.08
titre
0.22
15
26
125
103
12.82
126.78
3.5
2.6
0.20
0.20
e9/l
0.01
103
95
212
350
6.61
124.69
4.9
3.7
52.35
58.09
%
4.27
212
350
1340
7791
2.90
122.82
20.5
9.3
0.00
0.00
e9/l
1.52
1160
6352
317
802
4.46
115.13
2.2
1.8
1.36
1.53
g/l
2.57
268
691
171
246
7.46
114.21
1.4
1.2
51.73
51.26
u/l
0.01
154
208
173
253
7.35
113.85
1.7
1.7
1.28
0.86
g/l
1.42
120
192
754
3345
2.93
113.85
1.9
1.4
2.15
2.45
g/l
4.98
558
2040
993
5131
2.73
111.25
7.0
3.9
7.40
7.40
ph
0.34
251
974
144
177
8.65
109.89
8.4
3.3
—
—
—
0
0
195
339
6.22
108.68
1.4
1.4
—
18.49
—
0
7
592
2353
3.09
108.22
3.3
2.6
22.65
22.83
%
0.10
520
2004
194
337
6.23
108.19
1.4
1.4
—
—
—
0
0
575
2287
3.06
104.57
1.5
1.3
538.93
497.84
titre
0.20
131
491
259
615
4.65
101.49
2.1
2.6
3.01
2.96
g/l
0.29
234
557
157
236
7.10
100.59
4.3
2.0
—
—
—
0
0
268
660
4.49
100.25
2.1
2.5
3.53
3.67
g/l
0.68
242
602
268
661
4.49
100.05
2.1
2.5
7.08
7.40
g/l
1.98
243
602
675
3001
2.82
99.38
1.7
1.8
—
—
—
0
0
1384
8735
2.63
98.69
11.0
6.7
1.21
1.21
mmol/l
0.48
1128
7442
601
2526
2.91
98.20
3.2
2.5
2.30
2.32
g/l
0.41
565
2339
1295
7954
2.57
97.22
10.0
6.0
1.21
1.21
mmol/l
0.85
1216
7254
174
303
6.16
96.62
1.5
1.4
109.85
120.52
u/ml
0.32
33
62
917
4807
2.58
96.34
6.9
4.3
—
—
—
0
0
127
159
8.42
95.34
6.4
2.8
43.46
55.65
%
4.81
110
142
253
619
4.50
95.28
2.1
2.6
10.04
10.28
g/l
0.29
226
559
626
2745
2.80
93.88
3.2
2.5
12.41
13.03
umol/l
1.30
590
2557
227
518
4.78
93.20
2.0
2.4
38.08
37.50
g/l
0.59
201
460
98
90
11.36
92.50
1.4
1.7
8.91
8.82
ug/l
0.01
84
77
565
2385
2.85
90.71
8.8
5.8
1.05
1.04
mmol/l
0.37
534
2208
877
4608
2.52
90.35
4.7
2.7
2300.27
5597.66
umol/l
2.42
805
4045
208
454
4.96
90.01
1.9
2.0
11.92
11.48
mg/l
0.24
193
419
1228
7555
2.45
88.81
6.8
4.9
34.60
35.54
g/l
6.31
1148
7040
224
528
4.62
88.24
2.4
3.6
1.33
1.74
ratio
0.52
17
44
226
540
4.56
87.51
2.4
3.7
46.01
61.02
mg/l
0.59
173
440
226
542
4.54
87.09
2.4
3.7
37.26
79.54
mg/l
1.02
172
444
623
2831
2.69
86.12
5.6
3.4
0.81
0.82
mmol/l
0.79
590
2663
1813
13546
3.12
85.36
14.2
7.3
81.29
78.16
u/l
2.27
1766
12764
116
154
7.90
82.82
1.4
1.4
0.42
0.38
g/l
0.44
73
108
116
154
7.90
82.82
1.4
1.4
2.68
2.77
g/l
0.17
73
108
116
154
7.90
82.82
1.4
1.4
6.89
6.81
g/l
0.04
74
109
116
155
7.85
82.36
1.4
1.4
—
—
—
0
0
357
1223
3.30
82.11
1.4
1.4
—
—
—
0
0
419
1590
3.03
80.87
2.7
2.2
338.37
368.37
nmol/l
2.49
400
1457
215
526
4.43
80.62
1.3
1.3
—
—
—
0
0
474
1932
2.86
80.26
1.6
1.6
—
—
—
0
0
74
55
13.90
79.52
2.5
1.6
—
—
—
0
0
164
325
5.38
79.13
1.3
1.3
247.19
248.60
u/ml
0.02
109
199
829
4461
2.39
78.59
14.0
6.4
—
—
—
0
0
1741
12999
2.76
76.80
7.0
4.0
14.55
12.16
mm/h
6.89
1657
12003
213
543
4.24
75.57
2.1
1.7
—
—
—
0
0
179
404
4.74
74.13
2.4
3.9
—
—
—
0
0
682
3528
2.36
69.07
3.5
2.9
531.98
541.72
mosm/kgh2o
0.57
607
3036
73
67
11.24
68.80
2.8
1.9
50.65
144.58
ug/l
0.34
67
56
62
44
14.48
68.32
2.4
1.7
—
—
—
0
0
536
2501
2.52
68.10
1.6
1.6
—
—
—
0
0
902
5299
2.21
66.77
4.2
3.3
75.89
81.43
e6/l
0.04
750
4109
831
4733
2.23
66.36
4.1
3.1
—
—
—
0
0
162
369
4.67
66.23
1.5
1.6
—
—
—
0
0
192
499
4.13
66.19
1.9
1.6
0.22
0.24
g/l
2.15
177
471
196
519
4.05
65.86
1.8
1.6
1.14
1.19
g/l
1.22
183
489
139
284
5.16
64.63
1.6
1.3
—
—
—
0
0
60
45
13.69
64.05
2.5
2.6
2946.32
232.86
e6/l
0.75
38
28
835
4857
2.17
62.36
4.1
3.2
0.36
0.44
e6/l
0.63
695
3732
369
1490
2.78
62.36
1.5
1.4
—
—
—
0
0
689
3718
2.25
61.99
3.3
2.6
6.05
5.42
e6/l
0.22
629
3344
1153
7644
2.09
60.37
4.2
2.8
193.76
125.40
ug/l
2.60
1070
7041
1436
10377
2.15
59.20
7.1
4.8
6.68
6.74
mmol/l
0.47
1376
9718
983
6208
2.07
57.97
4.9
3.7
71.08
106.65
e6/l
1.00
791
4412
780
4542
2.12
56.94
2.9
2.2
3.15
2.95
mg/l
1.30
677
3865
182
508
3.82
56.63
3.4
2.8
3.56
3.65
g/l
0.29
173
475
771
4486
2.12
56.26
6.4
4.0
87.81
89.18
%
0.80
751
4376
429
1955
2.49
56.25
4.7
2.8
7.22
8.19
umol/l
0.39
375
1700
59
56
10.80
54.29
1.1
1.1
—
—
—
0
0
530
2720
2.26
52.60
3.7
2.2
30.58
29.84
s
1.31
522
2636
906
5702
2.02
52.47
4.6
3.2
39.20
33.55
u/l
0.94
868
5412
1181
8164
1.99
52.08
15.9
15.7
1.25
1.28
inr
0.52
453
2395
66
78
8.70
51.71
2.8
2.5
1432.47
1227.03
u/ml
0.20
66
78
1054
7184
1.91
46.58
2.9
2.2
76.66
76.77
nmol/l
0.04
975
6412
341
1517
2.48
46.43
4.8
3.8
—
—
—
0
0
71
105
6.96
45.93
2.5
2.7
36.16
42.11
%
0.86
30
56
141
381
3.89
45.81
5.0
3.9
—
—
—
0
0
90
170
5.48
45.58
1.2
1.2
—
—
—
0
0
93
182
5.29
45.30
2.4
2.5
—
—
—
0
0
906
5934
1.91
44.68
3.6
3.3
2.34
2.35
mmol/l
2.50
826
5207
477
2511
2.15
43.46
2.3
2.1
—
—
—
0
0
316
1425
2.43
41.49
5.5
3.7
1.21
1.23
mmol/l
3.16
283
1230
343
1611
2.34
41.06
10.6
7.6
10.58
9.88
mmol/l
1.01
325
1537
644
3866
1.95
40.44
2.4
1.8
1.18
1.18
mg/l
0.01
508
2949
111
276
4.19
40.38
2.6
2.7
—
—
—
0
0
830
5470
1.84
38.65
3.0
2.5
55.17
73.98
u/l
0.70
780
5061
73
134
5.60
38.12
1.7
1.3
4.75
0.89
u/ml
0.90
35
77
775
5025
1.85
37.86
3.5
3.0
2011.83
1440.06
ng/l
1.28
671
4284
133
395
3.52
37.55
5.6
4.6
2.44
2.54
mmol/l
0.13
92
261
178
631
2.98
37.55
1.3
1.2
0.24
0.78
u/ml
—
10
46
153
501
3.21
36.98
5.8
4.1
1.61
1.54
mg/l
0.43
143
461
1528
12201
1.86
36.64
5.8
4.3
—
—
—
0
0
798
5266
1.82
36.49
2.9
2.2
163.82
232.77
u/l
2.26
748
4940
72
136
5.44
36.45
1.2
1.1
74.00
143.60
titre
—
10
25
1015
7206
1.77
36.10
2.3
2.0
94.89
94.25
pmol/l
0.16
583
3778
393
2055
2.12
35.77
2.0
1.7
—
—
—
0
0
1988
17646
2.61
32.95
30.1
14.1
22.58
24.38
mg/l
1.70
1762
13926
336
1707
2.15
32.75
2.4
2.2
0.21
0.21
g/l
0.88
306
1599
141
474
3.11
32.57
5.7
4.3
7.42
7.42
ph
0.37
133
423
35
33
10.76
32.25
2.7
1.2
—
—
—
0
0
259
1194
2.33
31.96
3.3
2.9
6.59
5.57
e9/l
0.39
210
974
119
365
3.39
31.93
3.4
2.5
15.34
16.23
%
1.16
67
183
543
3301
1.86
31.57
2.1
1.7
1194.20
1167.26
nmol/l
0.27
437
2489
92
240
3.96
31.35
3.2
2.7
—
—
—
0
0
550
3370
1.85
31.12
4.5
3.8
416.03
438.86
ng/l
0.07
443
2634
431
2446
1.95
30.83
1.3
1.2
—
—
—
0
0
644
4150
1.79
30.79
1.9
1.5
20.45
20.54
nmol/l
0.05
584
3511
1450
11668
1.74
30.73
5.7
4.4
221.59
1908.96
e6/l
2.02
34
163
927
6685
1.68
29.10
5.0
3.6
91.40
53.80
ng/l
0.31
674
4620
374
2062
1.98
28.94
1.9
1.4
—
—
—
0
0
171
681
2.64
28.85
3.5
2.2
22.18
21.35
s
0.89
158
606
1770
15242
1.90
28.25
36.0
16.7
15.17
14.91
%
1.25
1754
14952
95
274
3.58
28.02
1.1
1.0
—
—
—
0
0
481
2940
1.82
26.92
1.3
1.3
35.84
33.08
iu/ml
0.19
159
957
94
277
3.50
26.84
1.1
1.1
—
—
—
0
0
1415
11510
1.67
26.74
4.0
3.1
61.72
48.65
u/l
2.96
1325
10738
101
314
3.33
26.53
3.8
3.2
—
—
—
0
0
457
2792
1.81
25.45
3.6
3.0
2.56
2.41
e6/l
0.11
272
1547
1116
8627
1.61
25.27
5.9
4.9
0.00
0.00
estimate
0.50
332
1631
125
454
2.86
25.15
1.3
1.2
34.96
32.43
u/ml
—
5
22
118
419
2.92
24.74
1.3
1.2
4.01
4.42
u/ml
0.05
15
40
1114
8642
1.60
24.60
4.5
3.6
0.00
0.00
estimate
0.75
338
1723
118
425
2.88
24.10
1.4
1.2
5.34
9.59
u/ml
0.53
23
68
1118
8717
1.59
23.88
4.5
3.6
0.01
0.01
estimate
0.16
304
1563
753
5374
1.62
23.20
3.3
3.0
—
—
—
0
0
671
4667
1.64
22.89
4.4
3.2
—
—
—
0
0
278
1494
1.99
22.82
12.4
9.0
—
—
—
0
0
166
728
2.39
22.77
1.5
1.2
—
—
—
0
0
60
145
4.23
22.69
1.1
1.1
—
—
—
0
0
97
325
3.08
22.52
1.3
1.2
—
—
—
0
0
934
7057
1.57
22.35
2.4
2.1
—
—
—
0
0
469
2992
1.73
22.14
3.5
2.8
0.70
1.20
e6/l
2.55
287
1737
1577
13459
1.64
22.03
4.5
4.0
14.83
14.78
pmol/l
0.31
1452
12205
351
2063
1.84
21.90
2.5
2.4
164.10
130.60
ug/g
0.60
284
1652
130
519
2.60
21.78
5.1
3.2
—
—
—
0
0
566
3815
1.66
21.66
1.4
1.3
1.22
1.52
u/ml
0.28
149
1006
122
475
2.66
21.49
1.2
1.2
110.83
84.05
titre
0.36
12
37
104
382
2.81
20.50
2.9
2.3
121.78
130.09
g/l
2.02
78
288
297
1694
1.87
20.29
6.5
4.0
7.36
7.39
ph
—
7
12
768
5647
1.56
20.14
4.4
2.4
—
—
—
0
0
440
2831
1.70
19.89
1.3
1.2
11.43
12.95
u/ml
0.19
134
1094
94
335
2.89
19.60
1.3
1.2
38.25
43.90
u/ml
0.12
12
31
487
3235
1.65
19.44
3.1
3.0
2.45
2.45
mmol/l
0.31
419
2847
287
1643
1.86
19.34
6.8
4.0
1.75
1.84
mmol/l
0.17
246
1367
64
182
3.59
19.33
1.6
1.5
—
—
—
0
0
50
120
4.24
19.11
1.2
1.1
—
—
—
0
0
219
1150
2.01
19.08
6.8
4.2
7.42
7.40
ph
1.25
52
135
1971
18109
2.02
18.93
30.5
16.3
139.33
139.64
mmol/l
6.58
1942
17642
1972
18152
2.00
18.36
31.6
16.5
3.98
3.97
mmol/l
0.81
1937
17655
219
1166
1.98
18.33
6.8
4.2
5.14
5.14
kpa
0.00
206
1121
29
18
16.32
18.32
1.2
1.2
—
—
—
0
0
29
44
6.67
18.31
1.3
1.1
—
—
—
0
0
152
705
2.24
18.28
2.8
1.8
1.86
1.89
ug/l
0.01
138
624
319
1923
1.77
18.07
1.3
1.3
—
—
—
0
0
72
232
3.18
17.89
1.7
1.5
35.10
32.48
g/l
0.85
62
205
283
1651
1.82
17.88
6.8
4.0
5.92
5.84
kpa
0.58
269
1607
62
184
3.44
17.57
1.8
1.6
—
—
—
0
0
891
6961
1.48
16.64
3.8
3.3
5.95
5.85
ph
0.32
44
495
67
217
3.15
16.53
1.6
1.6
—
—
—
0
0
1039
8382
1.46
16.35
4.1
2.6
—
—
—
0
0
638
4683
1.51
16.07
5.0
3.9
0.00
0.00
estimate
1.28
308
1568
274
1645
1.76
15.63
2.8
2.4
32.40
70.04
u/l
0.70
242
1396
178
932
1.99
15.58
11.3
10.1
24.11
24.35
mmol/l
0.41
172
904
29
53
5.53
15.25
1.0
1.0
—
—
—
0
0
1430
12348
1.47
15.24
4.9
3.8
—
—
—
0
0
109
484
2.32
14.55
1.4
1.2
—
—
—
0
0
36
83
4.39
14.52
1.6
1.3
—
—
—
0
0
246
1469
1.76
14.25
3.8
3.0
268.43
216.66
ng/l
0.87
222
1343
530
3835
1.51
13.98
1.8
1.7
49537475.63
29962619.00
pmol/l
0.22
432
3174
1780
16182
1.57
13.91
5.5
4.7
1.93
2.07
mu/l
0.66
1651
14778
41
108
3.85
13.88
1.1
1.0
—
—
—
0
0
25
22
11.48
13.78
1.1
1.4
—
—
—
0
0
72
272
2.70
13.53
1.3
1.2
4.67
5.72
u/ml
0.24
33
115
57
192
3.02
13.21
1.5
1.4
176994.95
102206.96
e6/l
0.24
37
112
77
306
2.57
13.09
3.0
3.0
—
—
—
0
0
34
82
4.20
12.97
2.1
2.9
1602.07
1970.07
ml
1.18
29
72
187
1061
1.83
12.83
1.3
1.3
29.22
53.66
au/ml
—
5
64
201
1169
1.79
12.71
2.4
2.4
21.73
24.50
au/ml
0.11
13
86
182
1027
1.84
12.71
2.9
3.5
4.55
4.50
pmol/l
0.11
154
912
26
51
5.15
12.69
1.8
1.6
—
—
—
0
0
719
5603
1.42
12.68
3.6
3.3
7.21
7.60
mmol/l
1.46
596
4738
270
1708
1.66
12.63
1.8
1.4
—
—
—
0
0
91
399
2.34
12.53
2.6
2.9
34.11
34.30
umol/l
0.03
85
363
1992
18733
1.82
12.49
19.8
10.2
26.88
26.20
u/l
0.68
1961
18078
26
52
5.05
12.42
1.2
1.1
—
—
—
0
0
225
1362
1.73
12.39
6.1
3.3
4.54
4.57
kpa
0.06
210
1324
224
1367
1.71
11.97
5.4
4.0
97.37
89.84
ng/l
0.59
198
1189
60
221
2.76
11.87
1.6
1.4
3045.21
1953.49
e6/l
0.69
47
155
308
2043
1.59
11.86
9.4
7.7
5.11
5.09
kpa
0.15
290
1953
308
2043
1.59
11.86
9.3
7.7
11.71
12.22
kpa
1.03
290
1955
1986
18709
1.77
11.69
32.0
16.3
82.90
77.83
umol/l
5.10
1986
18702
106
510
2.13
11.68
1.5
1.5
281.52
280.57
ug/g
0.01
65
304
670
5229
1.41
11.47
3.6
3.3
873.84
310.67
mg/l
1.41
461
3391
54
192
2.86
11.41
1.1
1.1
—
—
—
0
0
63
243
2.64
11.41
1.1
1.1
1.67
1.50
g/l
1.56
58
218
122
629
2.00
11.18
3.1
2.2
664.74
481.89
ug/l
0.25
115
591
304
2038
1.57
11.16
9.5
7.7
1.01
1.07
mmol/l
0.08
240
1609
35
97
3.65
11.07
1.0
1.0
—
—
—
0
0
54
197
2.79
10.90
1.2
1.2
—
—
nmol/l
—
0
0
52
190
2.78
10.47
1.3
1.1
—
—
—
0
0
54
202
2.72
10.41
1.5
1.2
—
—
—
0
0
58
227
2.60
10.24
1.2
1.2
0.16
0.39
nmol/l
—
7
18
161
935
1.78
10.23
1.4
1.2
—
—
—
0
0
691
5507
1.37
10.18
4.3
3.9
13.73
9.08
mg/mmol
1.45
447
3519
323
2242
1.52
10.08
1.4
1.3
—
—
—
0
0
25
58
4.35
10.05
1.5
1.3
—
—
—
0
0
30
81
3.74
9.87
1.4
1.2
—
—
—
0
0
36
110
3.31
9.86
8.1
3.6
—
—
—
0
0
212
1348
1.64
9.66
1.2
1.2
—
—
—
0
0
561
4355
1.39
9.61
4.3
2.3
—
—
—
0
0
49
182
2.73
9.60
1.5
1.5
6.00
6.59
mmol/l
0.75
44
168
50
188
2.70
9.57
1.5
2.2
—
—
—
0
0
34
103
3.34
9.45
1.0
1.1
—
—
—
0
0
641
5104
1.36
9.34
4.6
3.8
—
—
—
0
0
20
41
4.91
9.31
1.3
1.3
82.06
31.47
ug/l
—
10
21
159
946
1.73
9.31
11.8
10.8
—
—
—
0
0
53
210
2.56
9.16
1.2
1.2
—
—
—
0
0
21
46
4.60
9.06
1.5
1.7
73.01
94.24
nmol/24h
0.66
21
46
49
188
2.64
9.03
2.3
2.6
1.17
1.61
g/24h
0.37
23
97
1942
18368
1.57
9.00
23.9
13.3
—
—
—
0
0
68
306
2.26
8.90
1.7
1.9
4.47
5.05
mmol/24h
0.93
63
263
37
123
3.04
8.86
1.3
1.2
—
—
—
0
0
32
98
3.30
8.76
2.2
1.4
6.11
8.06
u/l
0.51
26
81
266
1829
1.52
8.63
10.2
8.1
95.10
95.57
%
0.59
251
1766
47
181
2.63
8.61
1.7
1.4
—
—
—
0
0
24
61
3.97
8.60
1.6
1.7
—
—
—
0
0
33
105
3.18
8.51
1.6
1.7
—
—
—
0
0
1733
16076
1.40
8.49
6.6
5.7
40.20
39.88
mmol/mol
0.65
1595
14857
22
53
4.18
8.46
1.0
1.0
—
—
—
0
0
52
213
2.48
8.41
1.6
1.3
42.07
40.53
mu/l
0.04
45
189
32
101
3.20
8.36
1.5
1.4
—
—
—
0
0
49
197
2.52
8.25
1.4
1.4
382.08
326.87
pmol/l
0.33
39
169
33
108
3.09
8.13
1.7
2.0
545.63
496.73
min
1.66
24
73
17
21
8.15
8.08
4.6
3.0
—
—
—
0
0
66
307
2.19
8.01
1.5
1.4
64.16
62.85
mmol/l
0.10
57
246
193
1263
1.58
7.82
1.7
1.4
—
—
—
0
0
48
198
2.46
7.68
1.1
1.1
—
—
—
0
0
38
141
2.73
7.52
1.7
2.2
651.37
632.10
ml
0.10
27
89
183
1195
1.58
7.48
4.6
5.0
—
—
—
0
0
44
177
2.52
7.43
7.3
3.2
—
—
—
0
0
88
469
1.91
7.42
1.6
1.4
9.97
9.55
u/l
0.09
66
371
27
83
3.28
7.38
1.3
1.6
—
—
—
0
0
12
9
13.40
7.38
1.2
1.1
—
—
—
0
0
74
374
2.01
7.27
4.5
2.6
—
—
—
0
0
50
219
2.31
7.04
1.7
1.6
52.84
60.08
%
0.56
34
138
112
659
1.74
6.87
2.7
3.5
0.31
0.28
g/l
0.21
64
284
72
369
1.98
6.82
2.8
1.6
—
—
—
0
0
38
150
2.56
6.70
1.1
1.1
—
—
—
0
0
62
304
2.07
6.64
1.3
1.1
0.55
3.38
u/ml
3.70
37
173
23
69
3.36
6.55
2.5
2.5
—
—
—
0
0
238
1691
1.46
6.55
10.6
8.5
115.60
121.62
g/l
4.21
227
1648
21
60
3.52
6.44
2.1
2.3
50.60
54.19
ug/l
0.13
21
60
17
42
4.07
6.35
1.6
1.6
—
—
—
0
0
34
131
2.62
6.30
1.3
1.4
—
—
—
0
0
9
5
18.07
6.26
2.7
1.0
—
—
—
0
0
44
195
2.28
6.07
9.1
6.7
7.02
7.36
mmol/l
0.29
35
162
44
196
2.27
6.00
1.5
1.3
271.89
279.09
mosm/kgh2o
1.41
37
141
23
74
3.13
5.89
2.7
1.6
26.01
28.63
umol/l
0.59
23
69
34
136
2.52
5.87
1.2
1.2
37.08
40.44
mg/l
0.19
26
111
169
1148
1.51
5.82
1.3
1.2
65.36
150.18
iu/ml
3.47
55
449
118
739
1.63
5.78
1.4
1.4
24.00
27.46
iu/l
0.58
97
616
558
4627
1.28
5.60
1.8
1.6
1.59
1.37
mmol/l
3.98
451
3888
9
7
12.90
5.58
2.7
1.0
—
—
—
0
0
16
33
4.88
5.43
1.6
1.4
—
166.29
—
0
7
13
21
6.22
5.38
2.5
1.8
—
—
—
0
0
131
859
1.56
5.32
7.9
4.3
—
—
—
0
0
41
188
2.20
5.26
2.7
1.6
—
—
—
0
0
27
102
2.67
5.24
1.1
1.1
1.08
1.05
ratio
0.41
12
41
32
132
2.45
5.21
1.2
1.1
254.37
264.61
mg/l
0.11
27
114
127
831
1.56
5.21
1.1
1.1
—
199.00
titre
—
0
14
17
49
3.49
5.17
1.2
1.1
—
—
—
0
0
240
1786
1.39
5.11
2.9
4.2
40.00
17.44
ug/l
0.40
191
1455
13
23
5.68
5.06
1.5
1.7
—
—
—
0
0
50
252
2.01
5.05
1.2
1.2
—
—
—
0
0
50
253
2.00
5.00
1.2
1.1
2.60
2.37
u/ml
0.05
28
135
71
404
1.78
4.97
2.8
1.6
637.48
739.86
e6/l
0.09
61
329
1792
17046
1.30
4.97
5.1
4.5
6.06
5.95
mmol/l
2.11
1635
15478
581
4908
1.25
4.89
1.6
1.4
—
—
—
0
0
162
1132
1.47
4.89
13.1
9.5
0.64
0.68
%
0.65
157
1124
2022
19612
1.49
4.87
43.9
20.7
254.90
249.57
e9/l
1.86
1987
19119
36
162
2.24
4.85
1.6
1.5
28.01
31.19
%
0.17
21
98
2021
19604
1.49
4.82
44.2
20.8
39.31
40.08
%
7.05
1909
18327
2022
19621
1.48
4.76
43.7
20.6
91.81
91.00
fl
9.44
2002
19329
2022
19623
1.48
4.73
43.6
20.6
30.33
30.31
pg
0.12
2001
19328
2022
19624
1.48
4.72
43.8
20.7
4.36
4.49
e12/l
18.99
1980
19071
22
79
2.80
4.71
1.0
1.2
—
—
—
0
0
2022
19625
1.48
4.71
43.9
20.7
10.45
6.76
e9/l
30.15
1979
19067
70
404
1.76
4.69
2.8
1.6
8.28
30.43
e6/l
0.83
58
317
2022
19629
1.48
4.66
44.1
20.8
130.74
135.22
g/l
28.93
2001
19332
72
423
1.73
4.55
1.7
1.7
12259.10
14627.23
e6/l
0.24
50
315
17
54
3.17
4.48
7.4
4.1
—
—
—
0
0
69
403
1.74
4.46
4.4
2.6
—
—
—
0
0
57
317
1.82
4.35
1.8
1.6
—
—
—
0
0
8
9
8.92
4.28
1.3
1.0
—
—
—
0
0
102
1521
0.65
4.25
1.3
1.4
—
—
—
0
0
69
410
1.71
4.21
2.5
1.4
3.69
3.78
mmol/l
0.31
62
385
111
745
1.52
4.12
9.0
4.5
24.75
24.76
mmol/l
0.01
104
705
19
68
2.81
4.12
1.1
1.2
—
—
—
0
0
14
35
4.02
4.10
1.2
1.2
—
—
—
0
0
174
1275
1.40
4.09
2.6
2.2
11.69
12.47
nmol/l
0.63
147
1127
87
554
1.59
4.07
2.0
2.2
9028.50
3623.13
u/l
0.40
26
222
18
63
2.87
4.06
1.9
1.6
—
—
—
0
0
12
26
4.64
4.05
1.4
1.3
—
—
—
0
0
49
267
1.85
4.01
1.2
1.1
1.55
5.96
u/ml
2.89
27
140
20
75
2.68
3.99
1.2
1.1
87.13
288.10
ng/l
—
8
19
28
124
2.27
3.97
1.2
1.1
—
—
—
0
0
74
457
1.64
3.93
3.0
2.0
—
—
—
0
0
31
144
2.17
3.93
5.8
1.8
9.88
11.29
%
1.05
31
144
49
270
1.83
3.88
2.6
2.5
—
—
—
0
0
107
723
1.50
3.87
2.4
2.6
—
—
—
0
0
25
108
2.33
3.76
1.9
1.5
—
—
—
0
0
11
24
4.60
3.74
1.1
1.2
0.02
1.66
u/ml
0.60
11
24
38
195
1.97
3.73
1.9
2.1
15.27
8.45
umol/l
0.41
20
141
11
25
4.42
3.62
2.5
1.0
—
—
—
0
0
11
25
4.42
3.62
2.5
1.0
—
—
—
0
0
11
25
4.42
3.62
2.5
1.0
—
—
—
0
0
14
40
3.52
3.60
1.2
1.1
—
—
—
0
0
227
1770
1.32
3.59
6.8
4.1
—
—
—
0
0
128
911
1.43
3.58
2.7
2.3
—
—
—
0
0
196
1498
1.34
3.56
1.5
1.6
—
—
—
0
0
80
523
1.55
3.40
1.4
1.2
—
—
—
0
0
8
14
5.73
3.34
1.0
1.3
—
—
—
0
0
87
583
1.51
3.31
3.1
2.1
—
—
—
0
0
22
96
2.30
3.26
3.4
3.1
7.45
7.42
ph
—
10
31
30
569
0.52
3.25
23.1
9.8
—
—
—
0
0
474
4074
1.21
3.24
4.0
3.6
—
—
—
0
0
19
78
2.45
3.21
1.8
1.4
25.41
25.39
umol/l
0.00
19
72
18
72
2.51
3.21
1.7
3.0
86.38
130.16
umol/l
—
8
45
87
588
1.50
3.19
3.0
2.1
—
—
—
0
0
45
259
1.75
3.15
1.2
1.1
0.30
1.23
u/ml
1.39
23
122
110
781
1.43
3.15
1.9
1.9
—
—
—
0
0
87
590
1.49
3.15
3.1
2.0
—
—
—
0
0
85
576
1.50
3.09
3.1
1.9
—
—
—
0
0
10
25
4.01
3.08
7.6
7.7
4.64
6.72
mmol/l
—
10
25
69
450
1.55
3.00
2.4
2.2
166.32
99.91
ug/min
0.40
42
275
5
5
10.02
2.98
1.0
1.0
—
—
—
0
0
21
94
2.25
2.96
1.2
1.2
—
—
—
0
0
45
265
1.71
2.93
5.2
5.2
406.60
356.10
umol/l
1.36
37
229
10
27
3.72
2.88
1.7
1.3
—
—
—
0
0
15
58
2.60
2.87
1.3
1.3
—
—
—
0
0
80
545
1.49
2.86
3.2
2.1
—
—
—
0
0
37
208
1.79
2.83
1.2
1.0
9.78
3.31
u/ml
0.54
18
100
48
291
1.66
2.82
1.6
1.4
—
—
—
0
0
11
33
3.35
2.81
2.5
2.1
14.66
17.73
umol/l
0.45
11
33
22
103
2.15
2.81
1.0
1.1
2.98
7.91
iu/ml
—
5
24
14
53
2.65
2.79
1.9
1.5
22.49
27.05
%
0.29
14
48
87
606
1.45
2.79
1.6
1.6
—
—
—
0
0
10
28
3.58
2.78
1.8
3.6
—
—
—
0
0
12
39
3.09
2.77
2.4
1.9
—
—
—
0
0
7
14
5.01
2.73
1.0
1.5
—
—
—
0
0
14
54
2.60
2.70
1.7
1.6
—
—
—
0
0
15
60
2.51
2.70
2.3
1.3
—
—
—
0
0
112
823
1.38
2.68
4.7
2.6
1.48
1.22
%
0.98
112
818
34
190
1.80
2.67
1.2
1.0
0.95
5.63
u/ml
2.52
11
77
11
35
3.15
2.64
1.2
1.1
—
—
—
0
0
11
35
3.15
2.64
1.2
1.1
—
—
—
0
0
11
35
3.15
2.64
1.2
1.1
—
—
—
0
0
19
87
2.19
2.57
1.5
1.4
—
—
—
0
0
14
316
0.44
2.55
1.8
1.5
—
—
—
0
0
147
1136
1.32
2.54
1.2
1.2
—
—
—
0
0
45
277
1.64
2.53
1.4
1.1
—
—
—
0
0
10
31
3.24
2.51
1.2
1.1
—
—
—
0
0
19
88
2.17
2.51
1.8
1.4
9.83
4.89
%
—
6
18
50
317
1.59
2.50
1.8
1.3
—
—
—
0
0
139
1071
1.32
2.46
5.0
3.1
122.78
128.80
g/l
2.04
134
1044
83
591
1.42
2.41
1.7
1.6
292.95
304.83
mu/l
0.14
73
539
9
27
3.34
2.39
1.7
3.6
—
—
—
0
0
14
307
0.45
2.39
1.8
1.4
—
—
—
0
0
188
1519
1.26
2.32
2.4
2.4
11.31
6.81
ug/l
0.51
160
1347
47
300
1.58
2.31
1.4
1.5
—
—
—
0
0
30
170
1.78
2.29
1.4
1.3
36885.82
118858.30
e6/l
0.71
17
117
6
13
4.63
2.27
2.3
7.6
—
—
—
0
0
6
13
4.63
2.27
1.3
1.2
—
—
—
0
0
32
186
1.73
2.24
4.4
1.8
—
—
—
0
0
5
9
5.56
2.21
1.2
1.8
1.80
1.94
%
—
5
9
15
309
0.48
2.18
1.7
1.4
—
—
—
0
0
38
234
1.64
2.17
1.4
1.5
0.19
0.31
nmol/l
2.19
31
188
7
19
3.69
2.15
1.1
1.2
—
—
—
0
0
9
30
3.01
2.14
1.0
1.1
—
—
—
0
0
11
42
2.63
2.14
3.9
2.3
6.83
7.54
mmol/l
—
6
22
62
429
1.46
2.13
1.8
1.9
5.82
5.06
iu/l
0.21
26
149
43
275
1.58
2.12
1.4
1.1
—
—
—
0
0
18
88
2.05
2.11
4.0
2.6
—
—
—
0
0
15
68
2.21
2.11
1.1
1.1
2201.27
1588.74
miu/ml
1.19
15
68
23
124
1.86
2.07
1.7
2.1
—
—
—
0
0
7
20
3.51
2.05
1.1
1.2
—
—
—
0
0
23
125
1.85
2.02
1.9
1.3
89.61
81.37
umol/l
0.60
23
125
16
76
2.11
2.02
1.1
1.0
0.14
1.05
u/ml
—
5
19
666
6086
1.14
2.01
3.3
2.8
—
—
—
0
0
9
32
2.82
2.00
1.8
1.6
—
—
—
0
0
77
563
1.38
1.97
6.2
6.5
1.34
1.37
mmol/l
0.09
62
494
76
1018
0.74
1.87
1.6
1.4
—
—
—
0
0
1812
17652
1.17
1.87
5.2
4.9
2.61
2.73
mmol/l
7.00
1681
16225
1781
17332
1.16
1.84
4.8
4.4
4.46
4.62
mmol/l
8.87
1659
16029
140
1128
1.26
1.82
7.8
7.2
24.82
24.44
mmol/l
0.50
130
1075
77
575
1.35
1.76
1.2
1.1
—
—
—
0
0
7
24
2.92
1.72
2.1
1.3
89.71
97.75
ng/l
—
7
24
70
518
1.36
1.70
1.2
1.3
190.13
222.40
miu/ml
0.33
23
238
6
19
3.16
1.66
1.0
1.5
47.50
48.79
umol/l
—
6
19
18
97
1.86
1.66
1.2
1.4
1.58
1.17
nmol/l
0.51
13
77
64
470
1.37
1.64
2.2
1.7
35.67
39.95
nmol/l
0.74
58
452
51
365
1.41
1.54
3.1
3.1
0.75
0.83
nmol/l
0.68
39
284
82
633
1.31
1.53
2.8
3.4
21.77
6310.18
u/ml
0.83
73
544
138
1138
1.23
1.50
3.2
2.9
—
—
—
0
0
7
28
2.50
1.45
1.0
1.2
2.14
1.84
umol/24h
—
7
28
23
140
1.65
1.45
2.4
2.2
1.50
2.24
u/field
—
8
58
87
687
1.28
1.40
1.1
1.1
—
—
—
0
0
1704
16623
1.12
1.36
4.4
3.9
1.42
1.29
mmol/l
7.56
1571
15171
15
82
1.84
1.35
1.1
1.1
1.81
1.92
u/ml
—
8
34
13
68
1.92
1.33
2.5
2.9
636.13
841.23
e6/l
—
8
57
17
98
1.74
1.31
13.6
11.1
0.56
0.62
mmol/l
0.51
17
92
41
292
1.41
1.30
1.2
1.2
—
—
—
0
0
5
18
2.78
1.28
1.2
1.1
—
—
—
0
0
10
48
2.09
1.27
1.3
2.7
—
—
—
0
0
49
362
1.36
1.27
2.2
3.5
21.25
1069.22
u/ml
0.89
43
344
1759
17212
1.12
1.25
4.8
4.3
1.36
1.45
mmol/l
14.97
1628
15815
16
92
1.74
1.25
1.8
1.7
3.73
4.67
u/field
0.16
11
68
13
70
1.86
1.24
1.4
3.0
—
—
—
0
0
51
384
1.34
1.19
5.8
3.6
25.69
26.95
mg/l
0.10
31
249
8
38
2.11
1.18
8.4
5.9
—
—
—
0
0
10
50
2.00
1.16
1.2
2.4
—
—
—
0
0
58
447
1.31
1.16
2.4
2.4
—
—
—
0
0
5
20
2.50
1.15
1.2
1.2
—
—
—
0
0
5
20
2.50
1.15
1.0
1.0
—
—
—
0
0
14
80
1.75
1.13
15.6
13.2
—
—
—
0
0
29
200
1.46
1.12
1.6
1.8
—
—
—
0
0
11
58
1.90
1.12
2.2
2.4
—
—
—
0
0
52
398
1.31
1.10
6.9
7.6
11.47
11.28
mmol/l
0.12
45
359
12
66
1.82
1.09
1.4
2.5
1.02
1.62
ug/l
0.85
12
61
52
399
1.31
1.08
6.9
7.6
105.93
105.20
mmol/l
0.55
45
360
129
1507
0.85
1.06
4.9
3.3
—
—
—
0
0
9
46
1.96
1.03
1.1
1.5
—
—
—
0
0
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
22
146
1.51
1.03
1.1
1.2
340.12
383.34
nmol/l
0.49
17
131
13
75
1.74
1.02
1.2
1.3
151.92
169.65
mmol/24h
0.61
13
75
104
873
1.20
1.02
4.0
3.4
—
—
—
0
0
0
31
0.00
0.96
0.0
2.3
—
2.93
—
0
13
87
726
1.21
0.93
5.9
5.5
1.91
1.60
%
1.01
79
680
18
118
1.53
0.91
1.1
1.1
0.36
3.80
nmol/l
—
5
22
16
102
1.57
0.90
3.4
2.4
—
—
—
0
0
86
722
1.20
0.87
6.1
5.5
0.90
0.89
%
0.17
78
677
6
31
1.94
0.84
1.0
3.4
—
—
—
0
0
10
57
1.76
0.83
1.3
1.5
—
—
—
0
0
28
205
1.37
0.83
3.1
2.5
—
—
—
0
0
194
2152
0.89
0.81
4.4
4.5
31.63
32.43
%
0.47
143
1466
25
181
1.39
0.80
1.1
1.0
0.08
0.30
u/ml
—
10
64
30
226
1.33
0.76
1.5
1.3
33.89
24.27
u/l
0.61
22
185
14
91
1.54
0.75
3.7
2.7
—
—
—
0
0
34
264
1.29
0.71
1.3
1.2
—
—
—
0
0
45
366
1.23
0.66
1.6
1.5
101.27
192.72
pmol/l
1.16
45
358
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
97
848
1.15
0.65
4.5
3.4
25.18
25.17
mmol/l
0.01
91
819
18
129
1.40
0.63
1.2
1.6
0.91
0.97
g/l
0.48
18
129
13
88
1.48
0.60
1.1
1.0
1.06
0.45
u/ml
—
5
26
83
723
1.15
0.60
5.1
4.8
—
—
—
0
0
210
1935
1.09
0.60
1.7
1.7
—
—
—
0
0
0
22
0.00
0.59
0.0
1.6
—
7.38
—
0
8
21
158
1.33
0.57
5.2
5.0
16.47
55.73
u/ml
—
7
49
6
98
0.61
0.52
2.2
2.1
—
41.83
—
0
7
52
443
1.18
0.52
4.5
4.3
—
—
—
0
0
1473
14949
0.95
0.47
38.3
18.2
330.04
332.48
g/l
18.82
1463
14830
76
853
0.89
0.45
1.5
1.7
—
—
—
0
0
171
1590
1.08
0.43
1.4
1.4
—
—
—
0
0
14
105
1.34
0.41
1.1
1.4
1.47
1.57
g/l
0.79
14
105
21
170
1.24
0.37
1.0
1.2
—
—
—
0
0
15
190
0.79
0.35
1.9
2.1
—
—
—
0
0
6
43
1.40
0.35
1.8
1.6
—
—
—
0
0
621
6044
1.04
0.33
4.9
5.0
4.07
2.84
ug/l
0.26
551
5410
54
488
1.11
0.28
1.1
1.1
—
—
—
0
0
8
65
1.23
0.27
1.0
1.1
—
—
—
0
0
9
75
1.20
0.25
1.1
1.5
—
—
—
0
0
29
255
1.14
0.24
1.1
1.0
5.24
2.60
u/ml
—
7
111
35
389
0.90
0.22
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
37.50
—
0
6
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
16
183
0.87
0.16
2.3
2.5
—
—
—
0
0
12
102
1.18
0.15
8.0
6.9
—
—
—
0
0
7
89
0.79
0.14
1.7
1.2
—
—
—
0
0
7
89
0.79
0.14
1.1
1.1
—
—
—
0
0
36
388
0.93
0.14
1.1
1.2
—
—
—
0
0
31
336
0.92
0.13
1.4
1.6
—
—
—
0
0
5
47
1.06
0.09
1.0
1.0
—
—
—
0
0
347
3515
0.98
0.08
2.9
3.1
0.74
0.76
ug/l
0.13
237
2343
10
110
0.91
0.05
2.0
1.4
208.51
161.99
pmol/l
—
10
110
19
179
1.06
0.05
2.3
1.4
—
—
—
0
0
14
130
1.08
0.04
1.0
1.0
—
—
—
0
0
15
154
0.97
0.00
3.2
3.3
77.96
33.89
mg/l
—
9
117
381
3812
1.00
0.00
4.9
4.0
1.02
1.02
kg/l
0.54
53
542
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
2.17
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
490.95
—
0
6

Mortality – FinRegistry

Association

Association between endpoint D3_OTHERWHITECELL and mortality.

Females

Parameter HR [95% CI] p-value
D3_OTHERWHITECELL 2.347 [2.09, 2.64] < 0.001
Birth year 0.992 [0.98, 1.0] 0.084

During the follow-up period (1.1.1998 — 31.12.2019), 1514 out of 5993 females with D3_OTHERWHITECELL died.

Males

Parameter HR [95% CI] p-value
D3_OTHERWHITECELL 2.421 [2.12, 2.76] < 0.001
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 1770 out of 5506 males with D3_OTHERWHITECELL died.

Mortality risk

Mortality risk for people of age

years, who have D3_OTHERWHITECELL.

N-year risk Females Males
1 0.184% 0.514%
5 1.121% 2.821%
10 3.172% 6.665%
15 6.287% 12.13%
20 10.342% 20.488%

Relationships between endpoints

Index endpoint: D3_OTHERWHITECELL – Other disorders of white blood cells

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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