Hypereosinophilic syndrome: The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1943 |
4. Check minimum number of eventsNone |
1943 |
5. Include endpoints |
2064 |
6. Filter based on genotype QC (FinnGen only) |
2064 |
Control definitions (FinnGen only)
- Control exclude
- D3_BLOODOTHER
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D70-D77
- Name in latin
- Aliae morbositates leucocytorum
Similar endpoints
↥List of similar endpoints to
Other disorders of white blood cells
based on the number of shared cases.
Similar with more cases:
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 15172 | 7959 | 7095 |
| Only index persons | 12791 | 6804 | 5987 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.21 | 0.23 | 0.20 |
| Only index persons | 0.24 | 0.25 | 0.23 |
| Median age at first event (years) | |||
| Whole population | 58.28 | 57.40 | 59.16 |
| Only index persons | 56.26 | 54.92 | 57.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2064 | 1100 | 964 |
| Unadjusted period prevalence (%) | 0.40 | 0.37 | 0.42 |
| Median age at first event (years) | 56.57 | 52.19 | 61.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1886
- Matched controls
- 18860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D72.1
ICD-10 Finland
Eosinophilia
6387.5
323.0
491
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
2087.8
323.0
1083
12
XW000
NOMESCO Finland
Bone marrow biopsy
26.7
323.0
518
263
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
599.3
268.3
260
5
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
14.6
187.1
329
268
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
41.1
173.6
219
60
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.5
118.2
485
1339
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
48.4
107.6
131
29
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
104.0
1056
5751
D70.89
ICD-10 Finland
Neutropenic splenomegaly
464.1
90.0
89
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
22.2
79.3
117
56
H02AB06
ATC
prednisolone; systemic
2.4
72.7
1018
6150
2888B
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOPENIA]
+∞
72.3
69
*
R50.9
ICD-10 Finland
Fever, unspecified
3.2
66.6
399
1439
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
94.9
66.4
73
8
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
59.5
569
2732
L01XX05
ATC
hydroxycarbamide; oral
17.8
55.1
87
51
M04AA01
ATC
allopurinol; systemic
3.0
52.7
342
1283
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
50.2
421
1850
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
47.8
292
1047
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
46.7
667
3806
189
Kela drug reimbursment
Imatinib
38.0
46.5
59
16
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.0
45.9
195
523
J01MA12
ATC
levofloxacin; systemic
2.5
45.6
431
2010
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.3
44.8
175
434
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
48.5
43.1
52
11
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
51.3
41.8
50
10
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
9.8
40.9
84
89
A02BC02
ATC
pantoprazole; systemic
1.9
40.6
1229
9239
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
40.2
235
810
JN4BD
NOMESCO Finland
Extensive body CT
2.8
40.0
284
1116
L01XE01
ATC
[U] imatinib; oral
36.6
39.2
50
14
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.9
39.1
262
991
WW500
NOMESCO Finland
Blood transfusion
5.0
39.0
132
282
D70.82
ICD-10 Finland
Drug-induced neutropenia
104.7
37.9
41
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
37.6
589
3425
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.7
37.3
172
494
L03AA02
ATC
filgrastim; parenteral
5.9
36.6
106
189
J32.4
ICD-10 Finland
Chronic pansinusitis
9.2
34.0
72
81
H02AB09
ATC
hydrocortisone; systemic
6.6
33.9
90
143
R03BB04
ATC
tiotropium bromide; inhalant
2.7
33.8
249
995
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.1
33.2
200
702
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
75.6
32.9
37
5
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
32.7
976
7048
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
15.0
32.4
54
37
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
62.8
32.1
37
6
J45.1
ICD-10 Finland
Nonallergic asthma
3.2
31.8
179
598
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
115.4
31.8
34
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
48.4
31.6
38
8
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.1
30.6
405
2169
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
30.0
224
900
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
29.7
431
2392
J01MA14
ATC
moxifloxacin; systemic
2.8
29.6
211
821
R03AC02
ATC
salbutamol; inhalant
1.7
28.8
972
7176
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.8
28.4
201
781
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
39.6
28.1
35
9
R03DC03
ATC
montelukast; oral
2.2
28.0
328
1656
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.3
27.9
106
255
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
27.9
323
1624
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.9
27.7
183
681
J01DB01
ATC
cefalexin; oral
1.9
27.5
1518
12951
C03CA01
ATC
furosemide; systemic
1.9
27.5
546
3390
TGC00
NOMESCO Finland
Bronchial lavation
5.3
27.5
86
169
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.7
27.3
125
356
D72.0
ICD-10 Finland
Genetic anomalies of leukocytes
+∞
27.1
26
*
C91.7
ICD-10 Finland
Other lymphoid leukaemia
76.3
26.8
30
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.4
26.8
99
232
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
26.6
187
722
ZX120
NOMESCO Finland
Intravenous
2.6
26.3
214
899
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
73.7
25.8
29
*
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
28.8
25.4
34
12
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
70.9
24.8
28
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
23.7
24.8
35
15
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
24.4
352
1932
R03AK08
ATC
formoterol and beclometasone; inhalant
4.0
24.4
102
269
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.4
24.1
213
935
127
Kela drug reimbursment
Transplant complication
6.6
24.0
62
96
ZX112
NOMESCO Finland
Subcutaneous
5.2
22.7
71
140
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
22.5
512
3285
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
22.5
418
2512
WW200
NOMESCO Finland
Immunization
4.2
22.3
86
211
316
Kela drug reimbursment
Imatinib
52.7
22.1
26
5
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
22.0
405
2422
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.6
21.5
100
289
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
4.7
21.4
74
163
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.0
21.0
128
452
A41.9
ICD-10 Finland
Sepsis, unspecified
3.7
20.8
93
261
L01BB05
ATC
fludarabine; systemic
77.7
20.7
23
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
20.7
387
2320
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
18.5
20.4
31
17
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
20.4
196
895
A04AA01
ATC
ondansetron; systemic, rectal
2.7
20.4
144
558
H02AB07
ATC
prednisone; oral
2.0
20.1
278
1490
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
20.1
733
5342
JN4AD
NOMESCO Finland
Body CT examination
2.5
20.0
164
688
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.7
19.7
140
543
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
74.3
19.7
22
*
152
Kela drug reimbursment
Nilotinib
106.1
19.6
21
*
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.1
19.5
77
194
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.0
19.4
80
209
A02BC01
ATC
omeprazole; systemic
1.7
19.0
516
3462
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
19.0
614
4320
B73
ICPC
Leukaemia
34.7
18.9
24
7
H02AB04
ATC
methylprednisolone; systemic
2.0
18.7
270
1470
R06.0
ICD-10 Finland
Dyspnoea
1.7
18.6
454
2951
R03BA05
ATC
fluticasone; inhalant
1.8
18.4
329
1938
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.8
18.3
78
210
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.3
18.3
176
806
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
19.5
18.2
27
14
R4110
NOMESCO Finland
Physiotherapy
1.7
18.0
480
3195
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
53.0
18.0
21
*
E0000UV
ATC
NA
1.6
17.7
690
5064
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.7
17.7
121
459
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
17.7
171
782
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
17.6
137
561
J01FF01
ATC
clindamycin; systemic
1.7
17.5
479
3208
J01AA02
ATC
doxycycline; systemic
1.6
17.5
1382
11954
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
17.4
127
501
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
17.4
281
1593
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
17.4
307
1796
J01CA04
ATC
amoxicillin; systemic
1.6
17.3
1442
12616
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
17.3
328
1963
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
17.2
309
1821
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
17.0
371
2323
D75.2
ICD-10 Finland
Essential thrombocytosis
63.9
16.8
19
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
16.3
259
1459
L04AD01
ATC
ciclosporin; systemic
4.3
16.1
59
139
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
16.0
118
468
J05AB11
ATC
valaciclovir; oral
1.9
15.8
232
1267
2888A
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOSIS]
+∞
15.6
15
*
UJF32
NOMESCO Finland
Coloscopy
1.6
15.5
447
3021
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
15.4
370
2376
J01FA09
ATC
clarithromycin; systemic
1.6
15.4
533
3774
N02AX02
ATC
tramadol; systemic, rectal
1.5
15.3
739
5652
1512
Kela drug reimbursment
Ibrutinib
28.8
15.2
20
7
R06AE07
ATC
cetirizine; oral
1.5
15.1
745
5717
WX110
NOMESCO Finland
Local anesthesy
1.5
15.1
1194
10121
N02BE01
ATC
paracetamol; systemic, rectal
1.6
15.1
1530
13729
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
15.0
305
1860
A46
ICD-10 Finland
Erysipelas
1.8
15.0
257
1484
L04AA06
ATC
mycophenolic acid; systemic
4.6
14.9
51
113
390
Kela drug reimbursment
Ibrutinib
25.2
14.7
20
8
A05AA02
ATC
ursodeoxycholic acid; oral
4.7
14.6
49
106
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.1
14.6
56
139
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.1
14.4
172
866
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
4.8
14.4
47
99
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
12.6
14.4
25
20
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.4
666
5028
212
Kela drug reimbursment
Gout
4.4
14.3
51
118
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.2
14.3
75
241
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.1
14.1
76
249
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
10.1
14.0
27
27
R53
ICD-10 Finland
Malaise and fatigue
1.7
13.9
349
2264
B03XA02
ATC
darbepoetin alfa; parenteral
4.4
13.9
50
117
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
13.8
204
1116
R03BA08
ATC
ciclesonide; inhalant
2.1
13.8
152
739
R05
ICD-10 Finland
Cough
1.7
13.8
334
2146
WX402
NOMESCO Finland
General anaesthesia
1.7
13.7
281
1716
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
13.6
702
5402
D07AC01
ATC
betamethasone; topical
1.5
13.6
577
4257
L01XX28
ATC
[D] imatinib; oral
75.7
13.6
15
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
13.5
200
1095
J46
ICD-10 Finland
Status asthmaticus
3.5
13.5
64
190
150
Kela drug reimbursment
Dasatinib
34.3
13.5
17
5
N06AX16
ATC
venlafaxine; oral
1.8
13.5
230
1323
WX892
NOMESCO Finland
Monitored bed care
2.1
13.4
147
714
XQ800
NOMESCO Finland
Prick test
2.2
13.3
138
654
A02BC05
ATC
esomeprazole; systemic
1.5
13.3
670
5129
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
13.3
286
1772
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
40.4
13.2
16
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
13.1
196
1075
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
7.9
13.1
29
37
P01AB01
ATC
metronidazole; oral, rectal
1.5
13.0
647
4932
J45.8
ICD-10 Finland
Mixed asthma
3.2
12.9
68
220
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
12.9
134
636
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
12.9
183
988
L01XE06
ATC
[U] dasatinib; systemic
50.3
12.8
15
*
A07AA02
ATC
nystatin; oral
2.3
12.8
126
580
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.1
12.8
49
122
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
12.8
565
4199
WX002
NOMESCO Finland
Sedation and analgesia
1.6
12.8
336
2204
R03AK11
ATC
formoterol and fluticasone; inhalant
3.5
12.7
58
168
R01AD08
ATC
fluticasone; nasal
1.5
12.6
473
3385
N05CF01
ATC
zopiclone; oral
1.5
12.6
533
3920
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.4
12.6
106
454
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.1
12.6
68
224
D07AB08
ATC
desonide; topical
1.9
12.5
184
1005
2883X
ICD-9 Finland
Diseases of white blood cells, Eosinophilia[EOSINOPHILIA, NUD]
+∞
12.5
12
*
R03DX09
ATC
mepolizumab; parenteral
+∞
12.5
12
*
3028
Kela drug reimbursment
Mepolizumab
130.8
12.4
13
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.4
12.4
102
433
N03AX16
ATC
pregabalin; oral
1.6
12.3
394
2713
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
11.7
12.3
22
19
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
12.3
768
6103
399
Kela drug reimbursment
Venetoclax
37.8
12.2
15
*
Z88.6
ICD-10 Finland
Personal history of allergy to analgesic agent
37.8
12.2
15
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
18.2
12.0
18
10
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
26.9
12.0
16
6
L01AA01
ATC
cyclophosphamide; systemic
11.1
12.0
22
20
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
12.0
154
796
ZX108
NOMESCO Finland
Inhalation
7.3
12.0
28
39
ZXA10
NOMESCO Finland
Bilateral
1.6
12.0
321
2110
L01AA02
ATC
chlorambucil; oral
13.5
11.9
20
15
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
11.9
220
1298
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.1
11.9
65
216
DHB20
NOMESCO Finland
Polypectomy of internal nose
4.6
11.9
40
88
L01XX52
ATC
venetoclax; oral
47.0
11.9
14
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
4.1
11.8
45
112
L03AA13
ATC
pegfilgrastim; parenteral
3.0
11.8
67
226
AA1AD
NOMESCO Finland
CT of head and brain
1.6
11.7
396
2760
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
11.7
122
580
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.9
11.7
37
76
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
7.4
11.7
27
37
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.7
11.7
50
138
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
23.0
11.6
16
7
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
11.5
448
3220
SPAT1254
SPAT
Administration of medicine
1.7
11.5
256
1597
297
Kela drug reimbursment
NA
120.7
11.4
12
*
R01AD09
ATC
mometasone; nasal
1.4
11.4
738
5882
R02
ICPC
Shortness of breath/dyspnoea
1.8
11.4
207
1217
L04AX01
ATC
azathioprine; systemic
2.5
11.3
86
349
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
11.3
178
993
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
7.0
11.3
27
39
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.7
11.2
74
276
SPAT1262
SPAT
Handing over of treatment supplies
1.6
11.2
312
2072
WZC30
NOMESCO Finland
Teaching
1.7
11.2
221
1332
R96
ICPC
Asthma
2.0
11.2
150
792
N02AA05
ATC
oxycodone; systemic
1.7
11.2
240
1485
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
11.1
110
511
SPAT1263
SPAT
Sampling
1.4
11.0
721
5747
D45
ICD-10 Finland
Polycythaemia vera
5.6
11.0
31
56
R01AD12
ATC
fluticasone furoate; nasal
1.5
11.0
469
3437
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
10.9
310
2065
GD1AD
NOMESCO Finland
Thorax CT examination
2.5
10.9
86
355
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.8
10.9
69
253
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.7
10.9
73
277
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
10.8
306
2036
R60.0
ICD-10 Finland
Localized oedema
1.8
10.8
183
1050
N05BA01
ATC
diazepam; systemic, rectal
1.7
10.7
226
1387
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
21.6
10.7
15
7
J45
ICD-10 Finland
Asthma
1.9
10.7
162
897
L01XE08
ATC
[U] nilotinib; oral
60.3
10.6
12
*
RS220
NOMESCO Finland
NA
4.7
10.6
35
76
B99
ICPC
Blood/lymph/spleen disease other
10.6
10.3
19
18
J01FA10
ATC
azithromycin; systemic
1.4
10.3
960
8110
J02AC03
ATC
voriconazole; systemic
18.9
10.3
15
8
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
10.2
94
425
C83.1
ICD-10 Finland
Mantle cell lymphoma
13.2
10.2
17
13
B01AB10
ATC
tinzaparin; parenteral
2.0
10.1
123
624
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
11.3
10.1
18
16
D07AA02
ATC
hydrocortisone; topical
1.7
10.0
216
1335
XG410
NOMESCO Finland
Flow-volume spirometry
2.4
10.0
84
362
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
40.3
10.0
12
*
JN6AD
NOMESCO Finland
CT of torso and neck
4.9
9.9
31
64
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
9.9
197
1192
120
Kela drug reimbursment
Hypogammaglobulinaemia
26.2
9.8
13
5
L01EL01
ATC
ibrutinib; oral
26.2
9.8
13
5
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
9.8
444
3285
L01XE27
ATC
[U] ibrutinib; oral
20.1
9.8
14
7
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
9.7
101
481
C07AB07
ATC
bisoprolol; oral
1.4
9.6
773
6340
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.6
9.6
69
273
N05BA04
ATC
oxazepam; oral
1.5
9.6
403
2935
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
9.5
197
1206
A41.8
ICD-10 Finland
Other specified sepsis
4.0
9.4
36
91
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.4
280
1886
L01EA03
ATC
nilotinib; oral
100.5
9.4
10
*
328
Kela drug reimbursment
Nilotinib
100.5
9.4
10
*
M05BA04
ATC
alendronic acid; oral
1.9
9.4
138
752
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
30.2
9.4
12
*
D75.1
ICD-10 Finland
Secondary polycythaemia
17.6
9.4
14
8
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
17.6
9.4
14
8
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.7
9.3
39
107
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
9.6
9.3
18
19
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
9.2
133
723
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
13.7
9.2
15
11
N03AE01
ATC
clonazepam; systemic
2.1
9.1
101
494
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
9.1
86
394
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.8
9.0
55
199
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
9.0
227
1467
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
3.3
9.0
44
137
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.0
9.0
111
569
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
9.0
144
812
J01DA01
ATC
[U] cefalexin; systemic
1.3
8.9
1038
8992
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
8.9
88
412
B02.9
ICD-10 Finland
Zoster without complication
2.1
8.8
96
466
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
8.8
363
2627
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
10.7
8.8
16
15
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.2
8.8
84
387
L01BB02
ATC
mercaptopurine; oral
6.0
8.8
23
39
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
8.7
205
1298
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
4.0
8.6
33
84
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.0
8.6
112
583
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.9
8.6
34
89
S18
ICPC
Laceration/cut
1.4
8.6
679
5521
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
8.6
177
1078
J02AC01
ATC
fluconazole; systemic
1.4
8.6
615
4926
A28
ICPC
Limited function/disability NOS
1.6
8.6
233
1534
9101
FHL
Bone biopsy
16.4
8.5
13
8
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.0
8.5
20
29
S97
ICPC
Chronic ulcer skin
2.1
8.5
97
482
J47
ICD-10 Finland
Bronchiectasis
3.4
8.5
40
121
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.7
8.5
35
95
B01AB05
ATC
enoxaparin; parenteral
1.4
8.5
483
3717
R03AC12
ATC
salmeterol; inhalant
2.2
8.5
82
378
L28
ICPC
Limited function/disability (L)
1.6
8.5
247
1653
R11
ICD-10 Finland
Nausea and vomiting
1.9
8.5
131
730
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
20.1
8.5
12
6
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.1
8.4
89
428
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
8.4
215
1393
D72
ICD-10 Finland
Other disorders of white blood cells
90.4
8.4
9
*
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
90.4
8.4
9
*
T90
ICPC
Diabetes non-insulin dependent
1.5
8.4
362
2645
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.1
8.4
44
145
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
8.4
116
621
D73.1
ICD-10 Finland
Hypersplenism
+∞
8.3
8
*
3027
Kela drug reimbursment
Benralizumab
+∞
8.3
8
*
N06AB04
ATC
citalopram; systemic
1.5
8.3
344
2487
R4120
NOMESCO Finland
Occupational therapy
2.0
8.3
108
567
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
8.2
169
1031
1XC02
NOMESCO Finland
NA
6.5
8.2
20
31
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
8.2
126
700
E000001
ATC
NA
1.5
8.2
333
2404
J01FA06
ATC
roxithromycin; oral
1.4
8.1
637
5167
1518
Kela drug reimbursment
NA
33.5
8.1
10
*
L04AA01
ATC
[U] ciclosporin; systemic
3.5
8.1
35
100
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
9.0
8.0
16
18
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
8.0
141
818
B01AA03
ATC
warfarin; systemic
1.5
8.0
323
2323
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
8.0
111
594
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
7.9
149
883
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.4
7.9
67
290
N03AX12
ATC
gabapentin; oral
1.6
7.9
233
1562
J20
ICD-10 Finland
Acute bronchitis
1.7
7.9
149
888
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
7.9
157
950
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.7
7.8
161
982
C03DA01
ATC
spironolactone; oral
1.7
7.8
174
1087
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.2
7.7
77
364
ED1AA
NOMESCO Finland
Mandipular X-ray examination
7.4
7.7
17
23
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.7
7.7
150
901
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
7.7
101
533
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
7.7
126
719
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
7.6
116
643
N06AX11
ATC
mirtazapine; oral
1.4
7.6
484
3787
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
7.6
112
616
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
25.1
7.6
10
*
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
3.8
7.6
30
80
SPAT1255
SPAT
Intravenous administration of medicine
1.9
7.5
108
588
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.9
7.5
29
76
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
4.4
7.4
25
57
L29.9
ICD-10 Finland
Pruritus, unspecified
2.9
7.4
43
151
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.9
7.4
41
141
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
13.4
7.4
12
9
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
3.7
7.4
30
82
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
7.3
96
503
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
7.3
362
2708
C91
ICD-10 Finland
Lymphoid leukaemia
+∞
7.3
7
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
7.3
7
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.3
7.3
34
104
N05CD07
ATC
temazepam; oral
1.6
7.2
195
1279
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
5.2
7.2
21
41
B82
ICPC
Anaemia other/unspecified
2.8
7.2
43
155
N06AX21
ATC
duloxetine; oral
1.6
7.2
165
1039
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
7.1
168
1065
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
30.1
7.1
9
*
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
30.1
7.1
9
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
30.1
7.1
9
*
C91.4
ICD-10 Finland
Hairy-cell leukaemia
30.1
7.1
9
*
324
Kela drug reimbursment
Dasatinib
20.1
7.1
10
5
DPA30
NOMESCO Finland
Sphenotomy
5.0
7.1
21
42
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
12.1
7.1
12
10
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.8
7.1
42
151
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.4
7.1
56
236
N06AA10
ATC
nortriptyline; systemic
3.0
7.0
38
129
R55
ICD-10 Finland
Syncope and collapse
1.6
7.0
170
1085
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
7.0
412
3173
N05AA02
ATC
levomepromazine; systemic
2.1
7.0
74
356
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.0
577
4691
ZXA05
NOMESCO Finland
Left side
1.4
7.0
398
3051
UDC00
NOMESCO Finland
Ear microscopy
1.8
7.0
120
695
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.7
7.0
45
169
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.0
319
2347
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.0
7.0
38
130
R03BA01
ATC
beclometasone; inhalant
1.5
7.0
220
1501
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
5.2
6.9
20
39
A01AB09
ATC
miconazole; local oral
1.7
6.9
140
852
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
7.5
6.9
15
20
N03AX09
ATC
lamotrigine; oral
2.1
6.9
74
362
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.8
6.9
27
72
J33.8
ICD-10 Finland
Other polyp of sinus
2.7
6.9
44
164
N05AH04
ATC
quetiapine; oral
1.5
6.9
244
1708
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.7
6.9
45
172
A02BC03
ATC
lansoprazole; oral
1.4
6.8
448
3513
TAB00
NOMESCO Finland
Lumbar puncture
2.0
6.8
78
391
M81.4
ICD-10 Finland
Drug-induced osteoporosis
8.3
6.8
14
17
R06.2
ICD-10 Finland
Wheezing
2.1
6.8
73
356
J05AB01
ATC
aciclovir; systemic
1.4
6.8
318
2350
UJF92
NOMESCO Finland
Capsular endoscopy
2.9
6.8
39
136
6BA02
NOMESCO Finland
NA
9.3
6.8
13
14
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
9.3
6.8
13
14
C08CA01
ATC
amlodipine; oral
1.3
6.8
549
4452
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.8
376
2869
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
40.2
6.8
8
*
R03DC01
ATC
zafirlukast; oral
3.1
6.7
35
116
P01BA02
ATC
hydroxychloroquine; oral
1.7
6.7
125
742
T78.4
ICD-10 Finland
Allergy, unspecified
2.1
6.7
70
337
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.8
6.7
114
657
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.1
6.7
75
373
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
6.7
95
516
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
22.6
6.7
9
*
N05AH02
ATC
clozapine; systemic
3.0
6.7
36
123
A06AD11
ATC
lactulose; oral
1.5
6.6
219
1509
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.9
6.6
91
490
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
5.5
6.6
18
33
M10.9
ICD-10 Finland
Gout, unspecified
1.9
6.6
98
542
R03DA04
ATC
theophylline; systemic, rectal
1.9
6.5
84
441
D11
ICPC
Diarrhoea
1.6
6.5
154
980
A03
ICPC
Fever
1.5
6.5
237
1668
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.1
6.5
71
350
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.3
6.5
58
260
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.7
6.5
40
149
R03AC13
ATC
formoterol; inhalant
1.9
6.4
83
436
9831/3-C42.1
ICD-O-3
T-cell large granular lymphocytic leukemia of bone marrow
70.1
6.4
7
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
6.4
68
331
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
6.4
127
769
N05BA06
ATC
lorazepam; systemic, sublingual
2.0
6.4
81
423
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
4.7
6.4
20
43
R06AX27
ATC
desloratadine; oral
1.4
6.4
399
3100
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
6.4
130
792
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
14.4
6.4
10
7
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
14.4
6.4
10
7
9109
FHL
Other measure in this category
14.4
6.4
10
7
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
6.4
104
593
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
6.4
125
755
-50
ICPC
Medication/prescr/renewal
2.1
6.4
67
324
GD1LA
NOMESCO Finland
GD
3.3
6.4
29
88
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.3
178
1181
XG405
NOMESCO Finland
Education on PEF monitoring
3.2
6.3
31
99
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
6.3
60
278
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.5
6.3
45
180
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.3
6.3
52
226
D07AD01
ATC
clobetasol; topical
1.5
6.3
229
1611
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.1
6.3
65
314
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
3.8
6.3
24
63
N18.8
ICD-10 Finland
Other chronic renal failure
2.4
6.3
48
200
2888X
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOPATHIA ALIA DEFINITA]
+∞
6.3
6
*
251
Kela drug reimbursment
NA
+∞
6.3
6
*
9875/3-C42.1
ICD-O-3
Chronic myelogenous leukemia, BCR/ABL positive of bone marrow
+∞
6.3
6
*
R03DX10
ATC
benralizumab; systemic
+∞
6.3
6
*
I42.3
ICD-10 Finland
Endomyocardial (eosinophilic) disease
+∞
6.3
6
*
D73.5
ICD-10 Finland
Infarction of spleen
+∞
6.3
6
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.2
890
7767
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
3.4
6.2
28
84
L04AA10
ATC
sirolimus; oral
26.8
6.2
8
*
C84.59
ICD-10 Finland
Other and unspecified T-cell lymphomas
26.8
6.2
8
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.0
6.2
79
412
3AC01
NOMESCO Finland
NA
4.1
6.2
22
54
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.4
6.2
50
213
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
6.2
111
655
C01CA24
ATC
epinephrine; parenteral
1.8
6.1
91
504
I51.4
ICD-10 Finland
Myocarditis, unspecified
5.8
6.1
16
28
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
6.1
258
1867
B01AB04
ATC
dalteparin; parenteral
2.0
6.1
75
388
R95
ICPC
Chron obstructive pulmonary disease
2.5
6.1
45
185
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
6.1
870
7586
B03XA01
ATC
erythropoietin; parenteral
4.0
6.1
22
55
R31
ICD-10 Finland
Unspecified haematuria
1.6
6.1
157
1019
J33.9
ICD-10 Finland
Nasal polyp, unspecified
3.9
6.1
23
60
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.2
6.1
56
258
ZXA00
NOMESCO Finland
Right side
1.3
6.1
418
3301
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
6.1
157
1024
DHA10
NOMESCO Finland
Biopsy of cavity of nose
4.9
6.0
18
37
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
4.9
6.0
18
37
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.1
6.0
67
332
E000002
ATC
NA
1.5
6.0
176
1180
WZA10
NOMESCO Finland
Long statement of health and health related matters
3.5
6.0
26
76
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
857
1864
7.15
307.65
8.4
3.8
250.1
247.2
u/l
0.12
822
1768
331
241
16.17
307.65
1.8
1.6
—
—
—
0
0
602
1256
6.35
289.88
3.7
2.7
9.5
10.7
g/l
6.15
548
1145
744
1885
5.61
289.35
5.0
2.5
1.8
1.8
%
0.41
693
1679
601
1395
5.67
255.07
5.4
2.6
71.3
69.7
e9/l
0.43
465
1064
1577
7846
5.28
248.64
15.1
5.8
3.6
2.8
%
9.12
1522
7307
1594
8094
5.26
241.96
15.2
5.9
33.3
27.7
%
25.93
1528
7555
1558
7981
4.88
227.98
14.0
5.7
51.3
57.4
%
34.63
1497
7478
525
1215
5.45
221.05
8.1
3.7
0.4
0.5
%
1.53
253
274
1603
8703
4.77
208.42
15.2
5.9
0.3
0.2
e9/l
23.68
1488
7625
1589
8621
4.66
205.49
13.8
5.7
4.7
1.9
e9/l
13.24
1490
7586
224
250
9.93
185.83
6.0
3.0
0.8
1.3
%
1.02
188
200
1631
9766
4.19
165.10
19.6
8.6
4.5
4.1
e9/l
4.28
1534
8524
153
127
12.93
154.88
2.9
2.0
34.1
44.0
%
1.22
24
16
481
1363
4.30
153.32
2.2
2.8
66.0
66.4
g/l
0.38
444
1250
401
1014
4.67
147.88
2.3
1.3
526.8
222.2
u/ml
2.38
373
941
134
107
13.32
138.72
2.4
2.2
11.0
12.5
%
0.46
63
53
235
396
6.57
135.88
2.3
1.6
—
—
—
0
0
208
318
7.16
131.88
6.6
5.3
380.2
830.0
iu/ml
0.50
25
44
1450
8696
3.24
131.59
9.9
6.1
10.3
11.6
umol/l
6.88
1406
8242
125
98
13.51
130.75
2.3
2.4
—
—
—
0
0
208
333
6.83
126.18
5.0
3.8
52.3
58.0
%
4.10
208
333
269
560
5.37
124.18
1.9
1.5
90.8
146.1
titre
0.76
13
23
124
105
12.50
123.68
3.4
2.5
838.3
508.8
e6/l
0.50
97
94
174
248
7.57
117.32
3.0
3.0
935.2
2062.5
u/ml
0.40
13
20
118
101
12.33
116.84
3.5
2.6
0.2
0.2
e9/l
0.04
97
93
1273
7448
2.85
114.02
20.6
9.3
0.0
0.0
e9/l
1.54
1109
6077
302
768
4.43
108.93
2.3
1.8
1.4
1.5
g/l
2.56
257
661
164
240
7.34
107.86
1.7
1.7
1.3
0.9
g/l
1.37
113
183
164
241
7.31
107.45
1.4
1.2
53.3
50.9
u/l
0.04
147
207
711
3201
2.86
103.62
1.9
1.5
2.1
2.4
g/l
5.03
525
1939
184
326
6.10
100.54
1.4
1.4
—
18.5
—
0
7
102
91
11.74
98.20
2.5
1.8
—
—
—
0
0
102
91
11.74
98.20
2.5
1.8
—
—
—
0
0
248
589
4.65
97.18
2.0
2.6
3.1
3.1
g/l
0.12
200
470
554
2248
3.00
96.91
3.3
2.6
22.7
22.9
%
0.09
489
1916
256
628
4.51
96.28
2.0
2.5
3.6
3.8
g/l
1.71
199
460
256
629
4.50
96.08
2.0
2.5
—
—
—
0
0
256
629
4.50
96.08
2.0
2.5
7.1
7.4
g/l
1.18
202
482
234
537
4.79
95.62
2.1
2.7
0.5
1.3
g/l
2.96
207
473
245
586
4.61
95.10
2.0
2.6
9.9
10.3
g/l
0.63
206
505
112
121
9.73
94.36
3.7
2.2
1480.5
685.2
e6/l
0.37
48
47
217
476
4.98
93.56
2.0
2.5
0.1
0.0
g/l
0.43
197
440
1322
8361
2.62
93.52
10.9
6.7
1.2
1.2
mmol/l
0.51
1068
7066
219
493
4.85
91.49
1.9
2.4
38.0
37.4
g/l
0.57
192
430
1233
7611
2.54
90.76
10.0
6.0
1.2
1.2
mmol/l
0.90
1151
6898
205
447
4.98
88.91
1.9
2.5
0.0
0.0
g/l
0.50
185
413
565
2420
2.84
88.49
3.2
2.5
2.3
2.3
g/l
0.37
530
2239
120
156
8.11
87.29
6.6
3.0
43.7
54.6
%
3.04
79
107
163
294
5.93
87.24
1.4
1.4
108.6
122.0
u/ml
0.41
30
60
91
83
11.42
86.27
1.5
1.6
9.0
8.7
ug/l
0.03
78
71
201
444
4.91
85.77
2.0
2.5
0.0
0.0
g/l
0.00
185
412
536
2273
2.83
85.16
8.8
5.8
1.1
1.0
mmol/l
0.39
507
2105
834
4398
2.50
84.97
4.8
2.7
2411.1
5681.7
umol/l
2.21
762
3824
588
2631
2.73
84.08
3.3
2.5
12.4
13.0
umol/l
1.16
550
2428
1169
7210
2.43
83.62
6.9
4.9
34.6
35.5
g/l
6.12
1089
6706
213
505
4.59
83.30
2.4
3.6
1.4
1.7
ratio
0.44
15
43
169
332
5.46
82.46
1.3
1.3
—
—
—
0
0
215
518
4.52
82.37
2.4
3.6
46.0
61.7
mg/l
0.60
166
421
215
520
4.50
81.96
2.4
3.6
37.8
80.6
mg/l
0.97
166
424
1732
12949
3.10
81.15
14.3
7.3
81.5
78.4
u/l
2.14
1685
12176
590
2701
2.66
80.08
5.7
3.4
0.8
0.8
mmol/l
1.17
557
2534
403
1529
3.03
77.88
2.7
2.2
338.0
369.2
nmol/l
2.59
385
1399
191
438
4.70
77.73
1.9
2.1
11.7
11.6
mg/l
0.06
179
403
1660
12424
2.72
71.99
7.0
4.0
14.5
12.2
mm/h
6.13
1580
11475
43
11
39.90
70.27
8.7
6.3
—
—
—
0
0
201
520
4.17
69.90
2.1
1.7
—
—
—
0
0
72
64
11.62
69.32
2.8
1.9
51.1
151.9
ug/l
0.35
66
53
151
314
5.11
68.91
1.3
1.3
249.9
249.9
u/ml
0.00
101
192
56
34
16.90
66.97
1.2
1.4
—
—
—
0
0
42
13
32.96
65.13
1.1
1.1
—
—
—
0
0
40
11
37.06
64.09
1.1
1.0
—
—
—
0
0
186
485
4.12
63.87
1.9
1.5
1.1
1.2
g/l
1.53
175
455
182
469
4.16
63.50
1.9
1.5
0.2
0.2
g/l
1.80
168
441
232
715
3.53
62.54
2.0
1.9
42.0
38.8
u/l
1.11
209
634
135
284
5.02
60.70
2.8
1.6
—
—
—
0
0
660
3545
2.27
60.26
3.4
2.6
5.7
5.4
e6/l
0.09
595
3117
162
403
4.28
59.16
2.6
1.6
—
—
—
0
0
795
4632
2.17
59.01
4.2
3.2
0.3
0.4
e6/l
2.28
667
3531
158
391
4.29
58.08
2.8
1.6
—
—
—
0
0
1373
9906
2.15
57.09
7.1
4.8
6.7
6.7
mmol/l
0.23
1315
9274
103
182
5.90
56.07
2.0
1.7
—
—
—
0
0
1093
7301
2.06
55.19
4.2
2.8
195.3
126.0
ug/l
2.45
1014
6724
539
2745
2.30
55.15
2.6
1.8
—
—
—
0
0
52
40
13.31
54.65
2.5
1.7
—
—
—
0
0
408
1870
2.47
52.78
4.9
2.8
7.3
8.2
umol/l
0.34
355
1626
740
4348
2.09
52.34
3.0
2.2
3.2
2.9
mg/l
1.69
640
3702
91
161
5.87
49.44
1.0
1.1
—
—
—
0
0
864
5459
2.00
49.27
4.7
3.2
39.5
33.6
u/l
0.95
829
5179
51
48
10.87
47.17
5.3
2.3
—
—
—
0
0
498
2598
2.21
47.13
3.7
2.2
30.5
29.8
s
1.11
490
2517
63
79
8.19
47.05
2.8
2.5
1414.1
1238.6
u/ml
0.17
63
79
165
491
3.57
46.61
3.5
2.8
3.5
3.6
g/l
0.32
156
459
134
348
4.05
46.05
1.8
1.4
—
—
—
0
0
69
103
6.90
44.26
2.5
2.7
40.0
41.9
%
0.14
19
32
1003
6858
1.90
43.61
3.0
2.2
76.9
76.9
nmol/l
0.02
929
6129
105
238
4.59
43.05
2.0
1.6
—
—
—
0
0
391
1912
2.29
42.90
2.2
1.7
—
—
—
0
0
371
1780
2.32
42.54
4.8
3.3
—
—
—
0
0
63
90
7.19
42.06
1.3
1.2
—
—
—
0
0
390
1928
2.26
41.58
2.3
1.7
—
—
—
0
0
860
5661
1.89
41.44
3.7
3.3
2.3
2.4
mmol/l
2.02
778
4939
169
555
3.23
40.75
2.8
2.7
—
—
—
0
0
274
1174
2.54
40.23
2.1
1.6
—
—
—
0
0
304
1373
2.42
39.82
5.4
3.5
1.2
1.2
mmol/l
2.58
272
1184
325
1529
2.34
38.75
10.6
7.6
10.7
9.9
mmol/l
1.15
307
1459
45
8
57.45
38.42
1.4
1.1
—
—
—
0
0
111
287
4.03
38.33
1.8
1.5
—
—
—
0
0
798
5228
1.86
38.22
2.9
2.5
54.8
56.9
u/l
0.93
750
4835
153
492
3.28
38.16
2.2
1.9
—
—
—
0
0
609
3695
1.92
36.75
2.4
1.8
1.2
1.2
mg/l
0.04
478
2823
70
128
5.63
36.71
1.7
1.4
5.7
0.6
u/ml
1.02
29
64
169
605
2.95
35.04
1.3
1.2
0.2
0.8
u/ml
—
10
45
91
222
4.24
33.96
1.9
1.5
—
—
—
0
0
68
131
5.33
33.71
1.2
1.1
60.0
147.5
titre
—
9
24
68
132
5.29
33.42
2.0
1.6
—
—
—
0
0
144
484
3.12
33.31
5.8
4.1
1.6
1.5
mg/l
0.40
135
444
757
5056
1.79
32.78
3.0
2.2
166.7
234.7
u/l
2.07
711
4743
732
4841
1.79
32.78
3.6
3.0
2004.8
1462.0
ng/l
1.14
633
4122
143
486
3.09
32.45
1.4
1.3
—
—
—
0
0
956
6887
1.72
31.27
2.3
2.0
94.4
94.4
pmol/l
0.02
552
3625
1897
16844
2.56
31.02
30.2
14.2
22.5
24.4
mg/l
1.73
1683
13303
53
88
6.16
30.69
2.0
1.5
—
—
—
0
0
114
351
3.38
30.43
3.5
2.5
15.4
16.2
%
0.93
64
178
57
104
5.61
29.97
1.3
1.2
—
—
—
0
0
316
1623
2.12
29.88
2.5
2.3
0.2
0.2
g/l
1.32
286
1518
517
3151
1.85
29.79
2.1
1.7
1209.5
1171.0
nmol/l
0.41
416
2385
52
88
6.04
29.55
2.0
1.5
—
—
—
0
0
524
3222
1.84
29.27
4.5
3.7
410.4
438.4
ng/l
0.08
422
2521
84
216
4.01
29.22
1.8
1.4
—
—
—
0
0
113
357
3.29
28.95
1.5
1.3
—
—
—
0
0
113
357
3.29
28.95
1.5
1.3
—
—
—
0
0
91
253
3.72
28.36
1.8
1.4
—
—
—
0
0
70
161
4.47
28.18
1.1
1.2
100.9
55.0
u/l
0.48
49
112
1379
11143
1.72
28.13
5.8
4.4
228.2
2020.9
e6/l
1.99
33
152
886
6408
1.67
27.40
5.0
3.6
95.3
53.7
ng/l
0.33
641
4424
55
106
5.30
27.26
2.0
1.4
—
—
—
0
0
141
526
2.80
27.03
1.7
1.6
0.2
12.4
iu/ml
0.49
18
97
91
265
3.55
26.48
1.3
1.2
—
—
—
0
0
1639
14004
1.83
26.43
36.5
17.2
14.3
13.7
%
29.60
1623
13678
1351
10963
1.67
26.02
4.0
3.1
62.4
48.9
u/l
2.91
1265
10228
60
130
4.72
26.00
2.1
1.7
—
—
—
0
0
603
3980
1.73
25.94
1.9
1.5
20.4
20.6
nmol/l
0.11
549
3377
188
829
2.39
25.56
7.5
4.5
24.0
24.0
mmol/l
0.02
178
747
131
486
2.81
25.36
2.0
1.7
—
—
—
0
0
47
84
5.70
25.26
5.5
2.9
—
—
—
0
0
120
432
2.89
24.56
1.3
1.2
35.0
32.5
u/ml
—
5
19
62
145
4.38
24.45
1.2
1.2
—
—
—
0
0
114
400
2.96
24.44
1.4
1.2
4.0
3.7
u/ml
0.04
15
39
114
406
2.91
23.79
1.4
1.2
5.3
7.5
u/ml
0.26
23
65
433
2662
1.79
23.56
3.6
3.0
2.6
2.4
e6/l
0.16
262
1470
452
2818
1.77
23.44
1.3
1.3
35.6
34.0
iu/ml
0.10
147
893
1062
8242
1.59
23.37
5.9
4.9
0.0
0.0
estimate
0.50
318
1576
1060
8230
1.59
23.23
4.5
3.6
0.0
0.0
estimate
0.00
314
1546
42
74
5.77
22.92
4.5
3.9
—
—
—
0
0
1065
8332
1.57
22.18
4.5
3.6
0.0
0.0
estimate
0.16
292
1513
26
28
9.39
21.77
1.2
1.2
—
—
—
0
0
1506
12850
1.64
21.08
4.5
4.0
14.8
14.8
pmol/l
0.29
1388
11655
94
322
3.01
21.03
1.3
1.2
1.0
5.9
u/ml
—
6
23
113
430
2.72
20.84
6.8
4.3
8.2
8.3
kpa
0.60
107
396
444
2850
1.71
20.44
3.5
2.8
0.7
1.2
e6/l
2.37
276
1648
25
28
9.03
20.33
1.6
1.3
—
—
—
0
0
538
3648
1.64
20.03
1.4
1.3
1.2
1.5
u/ml
0.28
144
958
117
463
2.62
19.98
1.6
1.2
—
—
—
0
0
113
440
2.66
19.93
4.4
3.4
24.8
24.8
mmol/l
0.00
101
382
60
160
3.83
19.89
3.6
1.5
—
—
—
0
0
101
372
2.80
19.83
2.9
2.3
122.6
130.1
g/l
1.70
75
280
64
181
3.62
19.49
3.5
1.5
—
—
—
0
0
329
1977
1.79
18.98
2.5
2.4
168.6
128.6
ug/g
0.70
264
1572
466
3088
1.66
18.84
3.2
3.0
2.5
2.4
mmol/l
0.30
401
2722
47
109
4.39
18.77
1.2
1.1
—
—
—
0
0
47
109
4.39
18.77
1.2
1.1
—
—
—
0
0
47
110
4.35
18.56
1.2
1.1
—
—
—
0
0
47
110
4.35
18.56
1.3
1.2
—
—
—
0
0
47
110
4.35
18.56
1.2
1.1
—
—
—
0
0
47
110
4.35
18.56
1.2
1.1
—
—
—
0
0
89
318
2.88
18.49
1.3
1.2
38.2
46.7
u/ml
0.19
12
29
47
111
4.31
18.35
1.3
1.2
—
—
—
0
0
32
54
6.00
18.25
1.6
1.5
—
—
—
0
0
20
19
10.62
18.23
1.7
2.2
—
—
—
0
0
276
1594
1.84
18.09
6.5
4.0
1.7
1.9
mmol/l
0.28
226
1276
261
1484
1.87
17.97
9.5
7.3
1.5
1.4
mmol/l
0.35
252
1430
34
62
5.56
17.92
5.2
1.6
—
—
—
0
0
414
2708
1.66
17.45
1.3
1.2
11.9
13.0
u/ml
0.13
125
1048
33
60
5.57
17.45
5.4
1.6
—
—
—
0
0
33
60
5.57
17.45
5.4
1.6
—
—
—
0
0
1881
17310
1.98
17.38
30.5
16.4
139.3
139.6
mmol/l
6.83
1853
16865
69
224
3.15
16.96
1.7
1.5
34.9
32.5
g/l
0.71
60
196
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
126
558
2.34
16.91
8.1
3.1
0.3
0.4
u/ml
0.35
79
317
40
89
4.56
16.83
1.1
1.2
128.1
79.9
u/l
1.37
34
80
1882
17352
1.96
16.83
31.6
16.6
4.0
4.0
mmol/l
1.34
1848
16877
201
1072
1.97
16.75
6.7
4.1
2.2
1.7
mmol/l
1.18
149
799
272
1601
1.81
16.70
6.6
4.0
5.9
5.9
kpa
0.67
258
1556
53
147
3.67
16.64
1.0
1.0
—
—
—
0
0
143
676
2.20
16.44
2.8
1.8
1.9
1.9
ug/l
0.03
129
600
996
8010
1.47
16.14
6.2
4.0
—
—
—
0
0
37
80
4.69
16.13
4.9
1.6
—
—
—
0
0
37
80
4.69
16.13
4.9
1.6
—
—
—
0
0
37
80
4.69
16.13
4.9
1.6
—
—
—
0
0
37
80
4.69
16.13
4.9
1.6
—
—
—
0
0
173
892
2.03
15.85
11.3
10.1
24.1
24.3
mmol/l
0.40
165
829
206
1131
1.91
15.74
6.7
4.1
5.1
5.1
kpa
0.02
192
1058
38
86
4.48
15.67
1.1
1.2
47.6
16.2
u/l
1.32
32
76
609
4480
1.51
15.17
5.0
3.9
0.0
0.0
estimate
1.28
295
1513
55
170
3.30
14.68
4.1
4.1
—
—
—
0
0
27
48
5.69
14.62
1.3
1.1
—
—
—
0
0
260
1568
1.75
14.62
2.8
2.4
32.8
71.7
u/l
0.69
232
1329
40
100
4.06
14.54
1.6
1.5
7.8
7.6
u/l
0.02
23
49
238
1412
1.77
14.14
3.8
3.0
266.5
221.5
ng/l
0.69
214
1291
29
57
5.15
14.11
1.4
1.3
—
—
—
0
0
42
113
3.77
13.81
2.0
1.4
18.2
19.5
u/ml
—
6
27
31
67
4.68
13.54
2.0
1.3
—
—
—
0
0
31
67
4.68
13.54
2.0
1.3
—
—
—
0
0
36
88
4.15
13.49
1.9
1.3
—
—
—
0
0
36
88
4.15
13.49
1.9
1.3
—
—
—
0
0
26
49
5.36
13.25
1.4
1.3
—
—
—
0
0
63
227
2.83
12.96
1.3
1.1
—
—
—
0
0
504
3666
1.50
12.92
1.8
1.7
52068561.2
31334858.0
pmol/l
0.22
411
3035
47
143
3.34
12.89
4.1
1.5
—
—
—
0
0
47
143
3.34
12.89
4.1
1.5
—
—
—
0
0
47
143
3.34
12.89
4.1
1.5
—
—
—
0
0
55
185
3.03
12.79
1.5
1.4
181894.8
104624.1
e6/l
0.25
36
107
299
1946
1.63
12.55
9.3
7.7
11.7
12.1
kpa
0.68
281
1865
299
1946
1.63
12.55
9.4
7.7
5.1
5.1
kpa
0.19
281
1862
1691
15408
1.54
12.49
5.5
4.7
1.9
2.1
mu/l
0.63
1570
14063
1724
15781
1.56
12.41
26.2
13.1
80.1
80.8
ml/min/173m2
0.62
1533
12975
178
1006
1.84
12.39
2.0
1.6
—
—
—
0
0
29
65
4.51
12.14
1.1
1.6
—
1903858.3
iu/ml
—
0
6
45
139
3.29
12.06
1.5
1.2
—
—
—
0
0
87
381
2.34
12.04
2.7
3.0
34.5
34.5
umol/l
0.00
78
324
685
5342
1.42
12.03
3.6
3.2
7.2
7.6
mmol/l
1.34
563
4495
121
606
2.06
12.01
3.1
2.3
669.0
492.1
ug/l
0.24
114
569
68
266
2.61
11.97
1.3
1.2
4.6
3.7
u/ml
0.12
19
90
191
1116
1.78
11.92
2.4
2.4
29.8
22.6
au/ml
—
8
63
295
1943
1.60
11.75
9.5
7.7
1.0
1.1
mmol/l
0.10
230
1510
66
257
2.62
11.73
1.3
1.2
4.8
5.7
u/ml
0.16
29
110
214
1298
1.72
11.72
5.4
4.0
96.7
90.4
ng/l
0.45
189
1134
216
1316
1.72
11.64
5.9
3.3
4.6
4.5
kpa
0.04
201
1278
30
72
4.21
11.54
1.4
1.2
—
—
—
0
0
172
984
1.82
11.51
2.8
3.5
4.6
4.5
pmol/l
0.12
145
876
1900
17893
1.78
11.33
19.9
10.2
26.6
26.2
u/l
0.34
1869
17267
35
96
3.69
11.24
1.1
1.1
—
—
—
0
0
57
211
2.75
11.19
1.6
1.4
3146.6
1952.0
e6/l
0.74
45
148
101
486
2.13
11.15
1.5
1.5
280.5
281.5
ug/g
0.02
64
292
787
6367
1.38
10.88
4.8
3.8
—
—
—
0
0
56
210
2.71
10.74
1.2
1.2
0.2
0.4
nmol/l
—
7
16
174
1024
1.76
10.59
1.5
1.5
—
—
—
0
0
1893
17870
1.72
10.36
32.2
16.5
82.9
77.9
umol/l
4.70
1893
17864
20
39
5.17
9.84
1.3
1.3
82.1
32.2
ug/l
—
10
20
658
5237
1.38
9.81
4.6
4.1
13.9
8.9
mg/mmol
1.52
429
3340
54
209
2.63
9.76
1.2
1.1
—
—
—
0
0
154
902
1.76
9.54
11.7
10.9
—
—
—
0
0
57
230
2.52
9.48
1.1
1.1
1.7
1.5
g/l
1.87
52
206
31
89
3.52
9.35
1.1
1.1
112.8
85.2
u/l
0.84
26
68
536
4155
1.39
9.30
4.3
2.3
—
—
—
0
0
31
90
3.48
9.20
1.0
1.0
—
—
—
0
0
31
90
3.48
9.20
1.1
1.1
49.5
24.1
u/l
1.32
24
64
16
27
5.96
9.12
2.8
3.1
53.6
41.4
u/l
—
5
10
31
93
3.37
8.77
2.2
1.4
6.1
8.2
u/l
0.53
26
76
46
174
2.68
8.73
1.6
1.5
6.0
6.6
mmol/l
0.94
41
160
63
279
2.30
8.58
1.2
1.1
—
—
—
0
0
47
183
2.60
8.44
1.4
1.4
405.9
271.0
pmol/l
1.08
36
135
49
197
2.52
8.25
2.0
1.3
—
—
—
0
0
49
197
2.52
8.25
2.0
1.4
—
—
—
0
0
49
197
2.52
8.25
2.0
1.4
—
—
—
0
0
49
198
2.51
8.17
2.0
1.4
—
—
—
0
0
1187
10497
1.31
8.03
3.3
3.0
—
—
—
0
0
33
109
3.06
8.02
1.3
1.2
—
—
—
0
0
49
200
2.49
8.01
2.0
1.3
—
—
—
0
0
18
39
4.65
7.88
1.4
1.2
—
—
—
0
0
71
343
2.11
7.85
1.9
1.6
—
—
—
0
0
298
2143
1.46
7.75
11.5
7.1
104.2
104.3
mmol/l
0.12
292
2089
12
9
13.40
7.38
2.9
3.3
—
—
—
0
0
37
137
2.73
7.36
1.7
2.2
666.0
629.1
ml
0.20
26
86
1650
15372
1.37
7.27
6.6
5.8
40.2
39.9
mmol/mol
0.73
1518
14201
116
679
1.75
7.25
3.5
1.8
—
—
—
0
0
49
212
2.34
7.09
1.7
1.6
52.1
60.8
%
0.69
33
134
47
200
2.38
7.06
2.1
1.3
—
—
—
0
0
84
449
1.91
7.04
1.6
1.4
9.8
9.3
u/l
0.10
64
359
70
352
2.02
6.99
1.9
1.3
—
—
—
0
0
231
1613
1.49
6.97
10.6
8.6
115.5
121.4
g/l
3.94
220
1555
1649
15406
1.35
6.78
31.8
15.2
39.1
39.7
%
2.28
1146
10969
21
58
3.65
6.75
2.1
2.3
50.6
54.5
ug/l
0.14
21
58
16
36
4.47
6.71
1.1
1.2
—
—
—
0
0
39
156
2.53
6.69
3.3
2.5
—
—
—
0
0
53
244
2.20
6.66
1.1
1.1
117.1
116.3
%
0.06
48
227
27
90
3.03
6.50
3.1
7.1
—
58.9
u/ml
—
0
26
59
290
2.06
6.30
1.2
1.1
0.4
2.7
u/ml
2.61
29
131
30
109
2.78
6.22
2.2
1.6
—
—
—
0
0
104
620
1.71
6.13
2.1
1.7
—
—
—
0
0
43
188
2.31
6.12
9.2
6.9
7.1
7.4
mmol/l
0.24
34
157
32
123
2.63
5.98
1.1
1.1
—
—
—
0
0
47
216
2.20
5.96
1.6
1.4
—
—
—
0
0
11
20
5.52
5.81
2.6
2.1
—
—
—
0
0
161
1095
1.51
5.54
1.3
1.2
65.9
148.4
iu/ml
3.02
51
429
8
5
16.06
5.41
1.0
1.0
—
—
—
0
0
16
43
3.74
5.37
1.4
1.2
—
—
—
0
0
12
26
4.64
5.26
4.1
5.2
—
—
—
0
0
12
26
4.64
5.26
1.2
1.0
—
—
—
0
0
111
703
1.61
5.23
1.5
1.4
24.4
27.2
iu/l
0.41
92
588
32
132
2.45
5.21
1.2
1.2
37.3
40.5
mg/l
0.17
25
108
157
1078
1.49
5.17
13.2
9.5
0.6
0.7
%
0.57
152
1071
230
1703
1.39
5.06
2.9
4.2
41.4
16.9
ug/l
0.42
184
1391
35
158
2.24
4.70
1.6
1.4
28.3
30.1
%
0.09
20
97
25
97
2.60
4.64
1.1
1.1
1.1
1.0
ratio
0.47
11
40
49
254
1.95
4.60
1.2
1.1
—
—
—
0
0
20
70
2.88
4.49
2.0
2.0
—
—
—
0
0
259
1994
1.34
4.47
2.2
1.8
1.6
1.5
%
1.28
230
1741
1929
18729
1.46
4.33
44.0
20.8
254.5
249.6
e9/l
1.53
1895
18261
18
61
2.97
4.28
2.1
1.2
—
—
—
0
0
524
4439
1.24
4.27
1.8
1.6
1.6
1.4
mmol/l
4.19
427
3721
66
386
1.73
4.26
2.9
1.6
669.4
748.0
e6/l
0.06
58
315
1929
18740
1.45
4.20
43.9
20.8
4.4
4.5
e12/l
17.86
1888
18213
1929
18745
1.44
4.14
44.3
21.0
130.9
135.2
g/l
25.95
1909
18465
1929
18746
1.44
4.13
44.0
20.9
10.6
6.8
e9/l
28.90
1887
18216
20
74
2.72
4.09
1.8
1.4
24.8
26.3
umol/l
0.07
20
68
72
438
1.67
4.05
1.3
1.3
—
—
—
0
0
1705
16288
1.27
4.04
5.1
4.5
6.1
6.0
mmol/l
2.00
1559
14796
65
386
1.71
4.00
2.8
1.6
8.3
31.1
e6/l
0.81
55
303
70
426
1.67
3.94
1.2
1.2
—
—
—
0
0
19
71
2.69
3.82
1.1
1.1
84.7
288.1
ng/l
—
7
19
46
250
1.86
3.81
1.2
1.1
—
—
—
0
0
37
187
2.00
3.79
1.9
2.1
15.9
8.5
umol/l
0.43
19
136
33
161
2.07
3.71
1.5
1.7
—
—
—
0
0
78
496
1.60
3.71
1.3
1.1
—
—
—
0
0
66
407
1.64
3.56
1.8
1.7
12176.1
14843.5
e6/l
0.26
45
305
82
534
1.56
3.54
2.0
2.2
9028.5
3504.3
u/l
0.41
26
214
164
1225
1.37
3.47
2.7
2.2
11.9
12.6
nmol/l
0.49
137
1072
21
87
2.43
3.47
2.0
1.7
—
—
—
0
0
14
363
0.38
3.45
1.8
1.4
—
—
—
0
0
64
395
1.64
3.45
2.5
1.4
3.7
3.8
mmol/l
0.26
57
370
16
391
0.40
3.44
1.8
1.5
—
—
—
0
0
14
362
0.38
3.43
1.8
1.4
—
—
—
0
0
77
498
1.57
3.43
1.4
1.1
—
—
—
0
0
14
361
0.38
3.41
1.8
1.4
—
—
—
0
0
14
361
0.38
3.41
1.8
1.4
—
—
—
0
0
19
430
0.44
3.39
1.6
1.4
—
—
—
0
0
18
70
2.59
3.38
1.7
3.1
86.4
118.4
umol/l
—
8
42
104
720
1.47
3.38
8.7
4.5
24.8
24.8
mmol/l
0.10
98
682
7
10
7.02
3.36
2.1
6.8
—
—
—
0
0
37
196
1.90
3.35
1.2
1.1
—
—
—
0
0
343
2852
1.24
3.26
1.6
1.5
—
—
—
0
0
101
1426
0.69
3.23
2.0
1.7
—
—
—
0
0
267
2160
1.27
3.21
23.0
26.5
1.2
1.4
inr
0.60
33
308
67
427
1.59
3.20
2.7
2.4
170.3
99.5
ug/min
0.42
41
257
71
459
1.57
3.19
1.4
1.4
—
—
—
0
0
22
99
2.24
3.06
1.2
1.1
—
—
—
0
0
33
174
1.91
3.05
1.1
1.0
—
—
—
0
0
159
2066
0.75
3.05
9.1
7.1
—
—
—
0
0
14
51
2.76
2.98
1.9
1.5
22.5
28.2
%
0.37
14
46
27
134
2.03
2.96
1.3
1.2
—
—
—
0
0
43
250
1.74
2.93
5.2
5.3
411.3
356.5
umol/l
1.44
35
221
9
23
3.93
2.77
7.9
5.7
4.5
6.9
mmol/l
—
9
23
21
97
2.18
2.77
1.0
1.1
3.0
8.4
iu/ml
—
5
22
67
445
1.52
2.72
1.2
1.1
—
—
—
0
0
19
85
2.25
2.70
1.8
1.4
9.8
4.1
%
—
6
16
10
32
3.14
2.64
1.2
1.1
—
—
—
0
0
30
163
1.85
2.58
1.4
1.3
36885.8
124311.9
e6/l
0.74
17
113
27
143
1.90
2.51
1.5
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
22
109
2.03
2.46
1.4
1.1
—
—
—
0
0
34
197
1.74
2.39
1.2
1.0
14.4
3.3
u/ml
0.65
12
76
107
801
1.35
2.32
4.6
2.6
1.5
1.2
%
1.10
107
796
11
41
2.69
2.28
3.9
2.0
6.8
7.5
mmol/l
—
6
22
11
41
2.69
2.28
2.4
1.0
—
—
—
0
0
21
106
1.99
2.25
1.2
1.1
1.0
1.1
u/l
—
10
54
7
18
3.90
2.25
1.1
1.1
—
—
—
0
0
180
1455
1.26
2.23
2.4
2.4
11.7
6.8
ug/l
0.54
153
1293
5
9
5.57
2.21
1.0
1.6
—
—
—
0
0
133
1038
1.30
2.18
4.8
3.1
123.5
128.6
g/l
1.51
128
1011
8
24
3.34
2.18
1.4
1.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
16
74
2.17
2.14
1.2
2.4
172.3
144.7
%
0.45
16
69
78
565
1.40
2.09
1.7
1.6
287.7
307.7
mu/l
0.23
68
516
9
31
2.91
2.07
2.7
2.2
16.1
17.3
umol/l
—
9
31
5
10
5.01
2.07
2.4
3.5
—
—
—
0
0
136
1075
1.28
2.04
7.8
7.3
24.7
24.4
mmol/l
0.38
125
1004
8
26
3.08
2.01
1.4
1.2
—
—
—
0
0
9
32
2.82
2.00
1.0
1.2
—
—
—
0
0
6
16
3.76
1.93
1.3
1.1
—
—
—
0
0
63
447
1.42
1.92
2.3
1.8
35.9
39.6
nmol/l
0.60
57
431
14
65
2.16
1.88
1.1
1.1
2143.5
1611.9
miu/ml
0.91
14
65
9
35
2.58
1.80
1.4
1.2
—
—
—
0
0
17
88
1.94
1.75
1.2
1.4
1.5
1.2
nmol/l
0.31
12
69
6
18
3.34
1.74
1.5
1.2
—
—
—
0
0
12
54
2.23
1.74
1.4
1.3
67.4
89.4
%
—
7
27
58
415
1.41
1.72
1.9
1.9
6.0
4.9
iu/l
0.30
25
144
66
484
1.38
1.70
1.2
1.3
190.1
227.5
miu/ml
0.39
23
224
6
19
3.16
1.66
1.0
1.4
47.5
51.1
umol/l
—
6
19
5
14
3.58
1.61
1.2
1.1
—
—
—
0
0
12
56
2.15
1.61
1.3
1.1
73.3
92.7
%
—
7
28
80
612
1.32
1.59
2.7
3.5
21.1
6561.6
u/ml
0.83
72
523
17
92
1.85
1.56
12.5
11.4
0.6
0.6
mmol/l
0.52
17
86
6
21
2.86
1.50
1.0
1.2
—
—
—
0
0
6
21
2.86
1.50
1.5
1.5
—
—
—
0
0
16
87
1.85
1.46
1.8
1.7
3.7
4.9
u/field
0.20
11
64
11
52
2.12
1.44
1.9
1.6
—
—
—
0
0
14
73
1.92
1.44
1.2
1.2
—
—
—
0
0
34
494
0.68
1.41
1.4
1.5
—
—
—
0
0
16
88
1.82
1.41
1.1
1.1
—
—
—
0
0
1694
16547
1.13
1.39
4.8
4.4
4.5
4.6
mmol/l
8.20
1580
15281
49
356
1.39
1.38
3.1
3.1
0.7
0.8
nmol/l
0.73
37
277
6
23
2.61
1.36
2.3
1.3
95.5
99.8
ng/l
—
6
23
5
17
2.95
1.36
5.6
5.2
—
—
—
0
0
22
135
1.64
1.36
2.5
2.2
1.5
2.2
u/field
—
8
54
1723
16858
1.13
1.34
5.2
4.9
2.6
2.7
mmol/l
6.71
1600
15469
5
18
2.78
1.28
3.4
1.9
—
—
—
0
0
160
1367
1.18
1.25
3.3
2.6
57.7
66.3
ml/min/173m2
2.01
84
541
1626
15873
1.11
1.25
4.4
3.9
1.4
1.3
mmol/l
7.67
1503
14484
6
25
2.40
1.24
1.0
1.2
2.2
1.8
umol/24h
—
6
25
6
25
2.40
1.24
1.3
1.3
—
—
—
0
0
8
36
2.23
1.24
3.1
1.9
1.2
1.2
mmol/l
—
8
36
8
36
2.23
1.24
1.0
1.3
—
—
—
0
0
17
100
1.71
1.23
1.6
1.3
—
—
—
0
0
5
19
2.64
1.21
1.2
1.1
0.0
2.2
u/ml
—
5
12
5
19
2.64
1.21
1.0
1.3
22.5
26.9
u/l
—
5
12
17
101
1.69
1.19
2.8
2.0
—
—
—
0
0
13
71
1.84
1.19
1.3
1.2
—
—
—
0
0
6
26
2.31
1.18
1.2
1.1
0.0
0.5
u/ml
—
6
20
8
38
2.11
1.18
1.0
1.5
108.9
100.0
%
—
8
33
11
57
1.93
1.17
1.5
1.2
—
—
—
0
0
46
342
1.35
1.16
2.2
3.6
22.3
1129.0
u/ml
0.88
40
325
18
110
1.64
1.15
1.1
1.1
—
—
—
0
0
32
225
1.43
1.12
1.5
1.4
0.2
0.3
nmol/l
1.64
26
179
199
1748
1.15
1.12
2.0
2.0
—
—
—
0
0
10
51
1.97
1.11
1.5
1.1
—
—
—
0
0
13
73
1.79
1.11
1.1
1.0
—
—
—
0
0
181
1582
1.16
1.09
2.0
1.9
—
—
—
0
0
10
52
1.93
1.06
1.5
1.1
—
—
—
0
0
7
33
2.12
1.05
1.4
1.1
—
—
—
0
0
7
33
2.12
1.05
1.4
1.1
—
—
—
0
0
20
129
1.56
1.05
1.4
1.4
11.9
12.0
mmol/l
—
5
36
18
114
1.58
1.02
1.1
1.1
0.4
3.9
nmol/l
—
5
21
84
691
1.22
1.01
5.8
5.6
1.9
1.6
%
1.04
76
648
0
29
0.00
0.97
0.0
1.2
—
—
—
0
0
32
234
1.37
0.93
1.5
1.5
—
—
—
0
0
100
847
1.19
0.92
1.4
1.3
—
—
—
0
0
273
2484
1.11
0.91
1.5
1.4
—
—
—
0
0
47
367
1.29
0.90
6.0
3.7
26.2
27.1
mg/l
0.07
30
237
49
385
1.28
0.90
1.7
1.7
—
—
—
0
0
51
636
0.80
0.85
2.0
1.6
3.9
3.9
mg/l
0.01
39
455
109
938
1.17
0.85
1.7
1.9
—
—
—
0
0
1671
16430
1.09
0.82
4.8
4.3
1.4
1.5
mmol/l
13.39
1551
15077
10
58
1.73
0.79
1.7
1.1
—
—
—
0
0
187
2072
0.89
0.77
4.4
4.5
31.6
32.3
%
0.36
135
1404
9
53
1.70
0.75
3.2
2.8
—
—
—
0
0
9
53
1.70
0.75
3.2
2.8
—
—
—
0
0
5
27
1.85
0.68
1.0
1.1
—
—
—
0
0
56
667
0.84
0.65
1.8
1.5
—
—
—
0
0
5
29
1.73
0.64
1.2
1.3
—
—
—
0
0
23
172
1.34
0.63
1.1
1.0
0.1
0.3
u/ml
—
5
50
85
739
1.16
0.63
1.6
1.8
—
—
—
0
0
10
63
1.59
0.61
1.5
2.4
1.2
1.6
ug/l
—
10
58
0
21
0.00
0.60
0.0
2.4
—
—
—
0
0
0
22
0.00
0.59
0.0
2.4
—
—
—
0
0
17
123
1.39
0.58
1.2
1.5
0.9
1.0
g/l
0.58
17
123
42
347
1.21
0.56
1.6
1.5
102.1
199.0
pmol/l
1.17
42
339
8
55
1.46
0.56
1.9
1.1
—
—
—
0
0
8
55
1.46
0.56
1.4
1.4
10.0
9.0
ug/l
—
8
55
28
221
1.27
0.55
1.6
1.4
29.8
24.1
u/l
0.35
21
182
93
824
1.13
0.55
4.6
3.4
25.3
25.2
mmol/l
0.09
87
794
20
151
1.33
0.54
5.0
5.1
16.5
57.6
u/ml
—
7
47
49
577
0.85
0.53
2.1
1.8
—
—
—
0
0
6
39
1.54
0.53
2.2
3.2
—
—
—
0
0
7
49
1.43
0.46
1.3
1.1
—
—
—
0
0
8
117
0.68
0.46
1.0
1.0
36.0
43.9
ng/l
—
8
68
11
78
1.41
0.43
1.1
1.0
—
—
—
0
0
23
185
1.25
0.42
1.1
1.2
—
—
—
0
0
448
4645
0.95
0.37
4.0
4.3
22.7
21.5
%
0.96
222
2278
8
116
0.69
0.37
1.0
1.0
282.1
298.5
ng/l
—
8
70
92
841
1.10
0.36
1.0
1.0
—
—
—
0
0
32
273
1.17
0.35
1.6
1.7
—
—
—
0
0
56
508
1.11
0.28
1.5
1.4
—
—
—
0
0
590
5764
1.03
0.27
4.8
5.0
4.2
2.9
ug/l
0.27
526
5163
28
244
1.15
0.25
1.1
1.0
5.2
2.6
u/ml
—
7
106
24
208
1.16
0.24
3.6
2.4
28.9
22.8
mg/l
—
7
52
23
199
1.16
0.23
1.4
1.6
—
—
—
0
0
33
294
1.12
0.23
1.5
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
34
307
1.11
0.20
1.6
1.6
—
—
—
0
0
12
100
1.20
0.18
1.7
1.8
7.3
7.6
mmol/l
—
7
60
57
533
1.07
0.17
4.8
4.1
4.0
3.9
mmol/l
0.54
49
498
23
211
1.09
0.11
1.3
1.3
6.7
7.5
mmol/l
0.47
17
150
330
3348
0.98
0.09
2.8
3.1
0.8
0.8
ug/l
0.08
224
2232
8
74
1.08
0.07
1.5
1.9
—
—
—
0
0
9
86
1.05
0.07
1.0
1.8
—
—
—
0
0
9
88
1.02
0.07
1.2
1.3
—
—
—
0
0
364
3637
1.00
0.00
4.8
4.0
1.0
1.0
kg/l
0.33
50
524
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
2.4
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
0.00
2.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_OTHERWHITECELL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_OTHERWHITECELL | 2.347 [2.09, 2.64] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.084 |
During the follow-up period (1.1.1998 — 31.12.2019), 1514 out of 5993 females with D3_OTHERWHITECELL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_OTHERWHITECELL | 2.421 [2.12, 2.76] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 1770 out of 5506 males with D3_OTHERWHITECELL died.
Mortality risk
Mortality risk for people of age
years, who have D3_OTHERWHITECELL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.184% | 0.514% |
| 5 | 1.121% | 2.821% |
| 10 | 3.172% | 6.665% |
| 15 | 6.287% | 12.13% |
| 20 | 10.342% | 20.488% |
Relationships between endpoints
↥Index endpoint: D3_OTHERWHITECELL – Other disorders of white blood cells
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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