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Other and unspecified disorders of white blood cells

DOID EFO Endpoint Browser PheWeb

D3_WHITEBLOODCELLNAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D72.8, D72.9
  • Hospital discharge: ICD-9 — 288[8-9]
  • Cause of death: ICD-10 — D72.8, D72.9
  • Cause of death: ICD-9 — 288[8-9]

2 out of 7 registries used, show all original rules.

1558

4. Check minimum number of events

None

1558

5. Include endpoints

None

1558

6. Filter based on genotype QC (FinnGen only)

1484

Control definitions (FinnGen only)

Control exclude
D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11640 6110 5442
Only index persons 9637 5134 4503
Unadjusted period prevalence (%)
Whole population 0.16 0.18 0.15
Only index persons 0.18 0.19 0.17
Median age at first event (years)
Whole population 59.46 58.68 60.22
Only index persons 57.31 56.07 58.71

-FinnGen-

Key figures

All Female Male
Number of individuals 1484 800 684
Unadjusted period prevalence (%) 0.30 0.28 0.31
Median age at first event (years) 57.47 52.98 62.71

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1558
Matched controls
15580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
61.7
307.7
245
47
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
558.4
307.7
315
7
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
8925.6
307.7
1212
6
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
15.8
307.7
339
269
XW000
NOMESCO Finland
Bone marrow biopsy
30.4
307.7
502
240
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
69.7
287.5
157
25
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
27.9
173.8
119
46
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.6
144.5
429
1183
L01XX05
ATC
hydroxycarbamide; oral
17.9
103.8
85
50
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
47.5
93.7
55
12
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
35.6
87.2
55
16
D70.89
ICD-10 Finland
Neutropenic splenomegaly
160.9
87.1
91
6
2888B
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOPENIA]
+∞
82.0
78
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
118.8
73.6
79
7
L03AA02
ATC
filgrastim; parenteral
6.9
70.0
112
173
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
70.0
889
5343
M04AA01
ATC
allopurinol; systemic
3.2
69.9
327
1181
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
9.4
69.8
85
95
R50.9
ICD-10 Finland
Fever, unspecified
3.0
63.3
352
1397
WW500
NOMESCO Finland
Blood transfusion
5.4
60.4
126
252
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
13.9
53.8
50
37
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
50.1
255
955
189
Kela drug reimbursment
Imatinib
78.5
47.2
53
7
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
45.8
494
2641
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.7
43.6
145
416
L01XE01
ATC
[U] imatinib
96.9
43.0
47
5
JN4BD
NOMESCO Finland
Extensive body CT
2.9
42.2
228
878
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
8.2
39.4
53
67
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
39.3
205
773
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
38.7
37
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
86.4
38.0
42
5
C91.7
ICD-10 Finland
Other lymphoid leukaemia
199.9
38.0
39
*
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
133.3
36.9
39
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.7
35.7
119
341
J01MA12
ATC
levofloxacin; systemic
2.2
34.3
350
1801
ZX120
NOMESCO Finland
Intravenous
2.7
34.1
197
782
A04AA01
ATC
ondansetron; systemic, rectal
2.9
33.3
171
637
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
64.8
33.1
38
6
127
Kela drug reimbursment
Transplant complication
6.7
32.0
51
78
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
31.9
214
913
H02AB06
ATC
prednisolone; systemic
1.9
31.0
783
5487
L01EA01
ATC
imatinib; oral
71.4
31.0
35
5
JN6AD
NOMESCO Finland
CT of torso and neck
6.7
30.7
49
75
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.6
30.1
192
799
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
84.3
29.8
33
*
H02AB09
ATC
hydrocortisone; systemic
4.7
29.4
69
152
JN4AD
NOMESCO Finland
Body CT examination
2.5
28.9
202
878
316
Kela drug reimbursment
Imatinib
101.9
27.7
30
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
27.5
302
1587
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
63.2
27.0
31
5
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
26.4
491
3090
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
23.7
26.2
37
16
C03CA01
ATC
furosemide; systemic
1.8
25.7
506
3235
B73
ICPC
Leukaemia
59.0
25.1
29
5
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
24.9
379
2228
WW200
NOMESCO Finland
Immunization
4.2
24.9
68
169
D45
ICD-10 Finland
Polycythaemia vera
7.7
24.3
34
45
A02BC02
ATC
pantoprazole; systemic
1.8
24.2
1063
8505
Z2221
NOMESCO Finland
Medical doctor
1.8
24.0
462
2924
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
19.9
23.5
35
18
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
22.8
531
3542
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.5
22.3
151
644
Z3231
NOMESCO Finland
Registered nurse
1.8
22.2
452
2896
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.1
22.2
93
308
TGC00
NOMESCO Finland
Bronchial lavation
4.1
22.1
62
157
J01DB01
ATC
cefalexin; oral
1.9
21.4
1281
11000
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
20.9
139
587
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
20.9
351
2115
J01MA14
ATC
moxifloxacin; systemic
2.3
20.8
165
756
A41.9
ICD-10 Finland
Sepsis, unspecified
3.4
20.7
77
237
L04AD01
ATC
ciclosporin; systemic
4.8
20.6
47
101
D72.1
ICD-10 Finland
Eosinophilia
111.5
20.6
22
*
212
Kela drug reimbursment
Gout
4.6
20.4
49
110
L01BB05
ATC
fludarabine; systemic
48.7
20.2
24
5
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
19.7
801
6123
D75.2
ICD-10 Finland
Essential thrombocytosis
106.4
19.6
21
*
A05AA02
ATC
ursodeoxycholic acid; oral
4.8
19.5
44
94
ZXE00
NOMESCO Finland
One hour or less
1.6
18.9
615
4433
L01XX52
ATC
venetoclax; oral
28.2
18.7
25
9
152
Kela drug reimbursment
Nilotinib
192.2
18.6
19
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
18.5
413
2695
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
18.4
174
855
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
18.4
307
1841
1512
Kela drug reimbursment
Ibrutinib
30.4
18.4
24
8
390
Kela drug reimbursment
Ibrutinib
30.4
18.4
24
8
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
18.2
117
487
R4110
NOMESCO Finland
Physiotherapy
1.7
18.1
438
2919
399
Kela drug reimbursment
Venetoclax
23.1
17.8
25
11
2888A
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOSIS]
+∞
17.7
17
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
17.7
359
2276
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
17.5
540
3825
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
17.3
171
854
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
17.3
283
1684
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.2
17.0
25
35
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
16.8
114
486
J05AB11
ATC
valaciclovir; oral
1.9
16.7
231
1301
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
16.7
276
1646
ZX108
NOMESCO Finland
Inhalation
7.0
16.6
25
36
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
27.9
16.5
22
8
L04AA06
ATC
mycophenolic acid; systemic
4.4
16.2
41
96
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
15.5
16.2
26
17
L01EL01
ATC
ibrutinib; oral
48.0
16.0
19
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.2
15.9
65
212
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.9
15.8
46
120
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
6.9
15.7
24
35
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
15.7
184
979
L01XX28
ATC
[U] imatinib
161.6
15.5
16
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
15.4
168
871
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
7.1
15.3
23
33
Z3226
NOMESCO Finland
Physiotherapist
1.8
15.2
292
1814
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
28.9
15.2
20
7
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
15.2
170
889
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
3.7
15.2
48
133
L01AA02
ATC
chlorambucil; oral
20.3
15.1
22
11
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
15.1
105
453
B03XA01
ATC
erythropoietin; parenteral
6.0
14.8
26
44
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.2
14.8
59
190
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
14.7
548
4023
N05AA02
ATC
levomepromazine; systemic
2.8
14.6
74
273
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
80.9
14.6
16
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
14.4
253
1531
1518, ,
Kela drug reimbursment
19.3
14.2
21
11
A46
ICD-10 Finland
Erysipelas
1.8
14.2
228
1342
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.1
14.1
58
190
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.3
14.1
112
512
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
14.0
152
785
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
4.1
14.0
38
94
R03BB04
ATC
tiotropium bromide; inhalant
1.9
14.0
175
951
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
12.8
13.9
24
19
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2.8
13.8
68
247
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
13.6
204
1176
J01MA02
ATC
ciprofloxacin; systemic
1.5
13.6
575
4320
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.1
13.5
57
190
328
Kela drug reimbursment
Nilotinib
141.2
13.5
14
*
150
Kela drug reimbursment
Dasatinib
141.2
13.5
14
*
Z2446
NOMESCO Finland
Social worker
2.2
13.5
118
562
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.9
13.4
63
223
J02AC03
ATC
voriconazole; systemic
18.4
13.4
20
11
N05CF01
ATC
zopiclone; oral
1.6
13.3
476
3444
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
9.8
13.2
26
27
WX892
NOMESCO Finland
Monitored bed care
2.1
13.2
129
642
A07AA02
ATC
nystatin; oral
2.3
13.0
97
432
SPAT1255
SPAT
Intravenous administration of medicine
2.2
13.0
112
530
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
12.9
100
452
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
12.8
526
3914
L01EA03
ATC
nilotinib; oral
131.0
12.4
13
*
WX402
NOMESCO Finland
General anaesthesia
1.6
12.4
308
2043
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
37.9
12.2
15
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
12.2
357
2462
L01AA01
ATC
cyclophosphamide; systemic
11.8
11.8
21
18
N05BA01
ATC
diazepam; systemic, rectal
1.8
11.8
200
1194
N03AE01
ATC
clonazepam; systemic
2.3
11.8
91
411
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
11.8
174
997
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.7
405
2896
B03XA02
ATC
darbepoetin alfa; parenteral
3.3
11.7
43
132
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
16.5
11.7
18
11
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
11.7
62
235
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
11.6
73
301
ZX112
NOMESCO Finland
Subcutaneous
3.3
11.5
43
133
L01XE06
ATC
[U] dasatinib
120.9
11.4
12
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
11.4
657
5202
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
4.3
11.3
29
69
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
11.3
329
2261
D75.1
ICD-10 Finland
Secondary polycythaemia
35.3
11.3
14
*
J01FF01
ATC
clindamycin; systemic
1.5
11.2
392
2806
XF600
NOMESCO Finland
Bloodpressure measurement
2.1
11.2
104
507
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
11.2
278
1840
E0000UV, ,
ATC
1.5
11.2
587
4563
120
Kela drug reimbursment
Hypogammaglobulinaemia
25.2
11.1
15
6
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.3
11.1
88
402
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.9
11.0
52
185
R53
ICD-10 Finland
Malaise and fatigue
1.6
11.0
345
2410
UJF32
NOMESCO Finland
Coloscopy
1.5
11.0
380
2712
N06AX16
ATC
venlafaxine; oral
1.7
11.0
205
1258
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
14.0
11.0
18
13
9101
FHL
Bone biopsy
43.6
10.9
13
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
10.9
156
886
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
60.4
10.6
12
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
5.3
10.6
21
40
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
10.6
240
1550
N02AX02
ATC
tramadol; systemic, rectal
1.4
10.6
619
4895
L01XE08
ATC
[U] nilotinib
110.7
10.4
11
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
110.7
10.4
11
*
H02AB07
ATC
prednisone; oral
1.7
10.4
201
1246
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
16.2
10.4
16
10
L01XE27
ATC
[U] ibrutinib
32.7
10.3
13
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
10.3
124
664
T90
ICPC
Diabetes non-insulin dependent
1.5
10.3
346
2449
A02BC01
ATC
omeprazole; systemic
1.5
10.3
392
2849
L04AA01
ATC
[U] ciclosporin
4.4
10.3
25
57
N06AB04
ATC
citalopram; systemic
1.6
10.3
291
1983
L04AD02
ATC
tacrolimus; systemic
4.9
10.3
22
45
Z51.5
ICD-10 Finland
Palliative care
2.0
10.2
118
623
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
13.2
10.2
17
13
N02AA05
ATC
oxycodone; systemic
1.6
10.1
259
1725
AA1AD
NOMESCO Finland
CT of head and brain
1.5
10.0
391
2853
N05AH02
ATC
clozapine; systemic
3.4
10.0
35
104
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
10.0
128
700
A06AD11
ATC
lactulose; oral
1.7
10.0
216
1377
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.7
10.0
31
85
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.9
259
1732
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
16.8
9.9
15
9
ZY010
NOMESCO Finland
Hospital outpatient
2.2
9.9
79
363
L04AX01
ATC
azathioprine; systemic
2.4
9.9
64
268
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
12.3
9.9
17
14
C83.1
ICD-10 Finland
Mantle cell lymphoma
12.3
9.9
17
14
B99
ICPC
Blood/lymph/spleen disease other
12.3
9.9
17
14
SPAT1263
SPAT
Sampling
1.4
9.9
591
4679
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
9.8
167
998
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.2
9.7
82
385
N03AX16
ATC
[U] pregabalin
1.5
9.7
331
2347
1XC02, ,
NOMESCO Finland
5.3
9.6
19
36
N02BE01
ATC
paracetamol; systemic, rectal
1.6
9.5
1325
12177
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
17.6
9.4
14
8
UJF92
NOMESCO Finland
Capsular endoscopy
3.1
9.4
38
124
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
9.4
88
431
J05AB01
ATC
aciclovir; systemic
1.5
9.4
303
2124
N07BA03
ATC
varenicline; oral
2.3
9.3
70
313
R60.0
ICD-10 Finland
Localized oedema
1.7
9.3
176
1082
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
9.3
206
1321
J01CA04
ATC
amoxicillin; systemic
1.5
9.3
1194
10753
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
9.3
202
1290
N05AF03
ATC
chlorprothixene; systemic
2.9
9.2
41
142
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.1
9.1
37
121
ZXD05
NOMESCO Finland
Urgent procedure
1.4
9.1
441
3350
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.2
9.1
72
330
R03AC02
ATC
salbutamol; inhalant
1.4
9.1
776
6499
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
9.1
267
1832
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.1
9.1
89
444
R4190
NOMESCO Finland
Nutritional therapy
2.4
9.0
62
267
C95.9
ICD-10 Finland
Leukaemia, unspecified
36.9
9.0
11
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
9.0
157
944
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.0
9.0
104
550
R4120
NOMESCO Finland
Occupational therapy
2.0
9.0
98
508
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
8.9
582
4655
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
24.2
8.9
12
5
D07AB08
ATC
desonide; topical
1.7
8.9
155
932
L04AX03
ATC
methotrexate; systemic
1.8
8.9
139
810
R05
ICPC
Cough
1.5
8.9
338
2448
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.4
8.9
57
238
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.3
8.9
65
288
A02BC05
ATC
esomeprazole; systemic
1.4
8.8
563
4483
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
8.7
8.8
18
21
B01AB10
ATC
tinzaparin; parenteral
1.8
8.8
148
881
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
3.5
8.8
30
88
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
50.3
8.7
10
*
A28
ICPC
Limited function/disability NOS
1.6
8.6
240
1624
J01AA02
ATC
doxycycline; systemic
1.4
8.6
1125
10067
N06AX11
ATC
mirtazapine; oral
1.4
8.6
465
3594
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.1
8.6
76
364
J12.8
ICD-10 Finland
Other viral pneumonia
4.8
8.6
19
40
RS220, ,
NOMESCO Finland
3.6
8.6
27
75
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
11.6
8.6
15
13
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
8.6
1012
8899
R05
ICD-10 Finland
Cough
1.5
8.5
292
2068
N03AX09
ATC
lamotrigine; oral
2.2
8.5
68
313
R02
ICPC
Shortness of breath/dyspnoea
1.6
8.5
185
1181
L03AA13
ATC
pegfilgrastim; parenteral
2.3
8.5
63
281
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.3
8.5
60
262
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
8.5
215
1425
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.8
8.4
140
830
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
90.5
8.4
9
*
B84
ICPC
Unexplained abnormal white cells
90.5
8.4
9
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
8.4
163
1010
D07AC01
ATC
betamethasone; topical
1.4
8.4
494
3874
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
8.4
192
1242
9831/3-C42.1
ICD-O-3
T-cell large granular lymphocytic leukemia of bone marrow
+∞
8.3
8
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.0
8.3
35
117
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
8.3
339
2485
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
8.3
115
646
SPAT1254
SPAT
Administration of medicine
1.6
8.3
207
1366
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
8.2
183
1174
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.4
8.2
29
87
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
8.2
286
2033
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.8
8.2
40
146
TAB00
NOMESCO Finland
Lumbar puncture
2.2
8.1
70
332
SPAT1262
SPAT
Handing over of treatment supplies
1.5
8.1
249
1722
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.8
8.1
24
64
L28
ICPC
Limited function/disability (L)
1.5
8.0
244
1683
K59.1
ICD-10 Finland
Functional diarrhoea
2.0
8.0
82
416
Z2445
NOMESCO Finland
Psychologist
2.3
7.9
58
257
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
4.0
7.9
22
56
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.9
7.9
35
121
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
3.6
7.9
25
70
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.4
7.8
53
227
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.7
7.8
42
161
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
7.8
341
2532
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.9
7.8
89
470
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.8
619
5085
N05BA04
ATC
oxazepam; oral
1.4
7.8
361
2710
N05AH04
ATC
quetiapine; oral
1.5
7.7
237
1640
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
3.4
7.7
27
81
J01FA10
ATC
azithromycin; systemic
1.3
7.7
779
6636
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.0
7.6
32
107
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.6
546
4407
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.0
7.6
77
389
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
18.4
7.6
11
6
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
7.6
191
1263
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.5
7.6
25
72
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
7.5
74
370
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.8
7.5
36
130
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.2
7.5
58
264
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.2
7.5
61
284
A03
ICPC
Fever
1.5
7.4
218
1491
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
7.4
106
601
Z31.5
ICD-10 Finland
Genetic counselling
2.1
7.4
72
358
324
Kela drug reimbursment
Dasatinib
80.5
7.4
8
*
N05AB03
ATC
perphenazine; systemic, rectal
2.3
7.4
53
233
RD210, ,
NOMESCO Finland
3.0
7.4
32
109
B02.9
ICD-10 Finland
Zoster without complication
1.9
7.4
94
514
B01AB05
ATC
enoxaparin; parenteral
1.4
7.4
436
3407
TQW99
NOMESCO Finland
Other minor procedure on skin
2.0
7.4
77
394
TPH00
NOMESCO Finland
Phlebotomy
8.4
7.3
15
18
J02AC01
ATC
fluconazole; systemic
1.4
7.3
503
4029
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.3
220
1514
6BA02, ,
NOMESCO Finland
10.9
7.3
13
12
2888X
ICD-9 Finland
Diseases of white blood cells, Other specified disease of white blood cells[LEUCOCYTOPATHIA ALIA DEFINITA]
+∞
7.3
7
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.1
7.3
71
354
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
4.2
7.3
19
46
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
7.3
83
438
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.4
7.3
49
210
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.3
7.3
26
79
ZXA05
NOMESCO Finland
Left side
1.4
7.2
343
2580
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
4.3
7.2
18
42
P01BA02
ATC
hydroxychloroquine; oral
1.8
7.2
112
652
N05AH03
ATC
olanzapine; systemic
1.9
7.2
86
461
N03AX12
ATC
[U] gabapentin; oral
1.5
7.2
228
1587
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.6
7.2
151
956
374
Kela drug reimbursment
Ruxolitinib
30.2
7.1
9
*
B74
ICPC
Malignant neoplasm blood other
20.1
7.1
10
5
N05CD07
ATC
temazepam; oral
1.6
7.1
164
1062
R06AE07
ATC
cetirizine; oral
1.3
7.1
581
4777
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
2.6
7.1
39
152
R04.2
ICD-10 Finland
Haemoptysis
2.3
7.0
52
232
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.0
528
4282
3AC01, ,
NOMESCO Finland
3.9
7.0
20
52
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.4
7.0
24
71
R55
ICD-10 Finland
Syncope and collapse
1.6
7.0
155
994
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
7.0
100
569
C07AB07
ATC
bisoprolol; oral
1.3
6.9
686
5792
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.8
6.9
34
125
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
6.9
121
730
C03DA01
ATC
spironolactone; oral
1.6
6.9
169
1111
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
6.8
126
771
R11
ICD-10 Finland
Nausea and vomiting
1.7
6.8
117
702
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
5.7
6.8
18
32
C91.4
ICD-10 Finland
Hairy-cell leukaemia
40.2
6.8
8
*
E000002, ,
ATC
1.6
6.8
145
922
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
16.8
6.7
10
6
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.6
6.7
36
138
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.9
6.7
84
457
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
3.4
6.7
23
68
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
2.9
6.7
31
110
J20
ICD-10 Finland
Acute bronchitis
1.6
6.7
140
885
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
22.6
6.7
9
*
J01FA09
ATC
clarithromycin; systemic
1.4
6.7
411
3227
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.8
6.7
32
116
R51.80
ICD-10 Finland
Headache
1.5
6.6
207
1434
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.6
367
2830
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
6.6
107
630
M10.9
ICD-10 Finland
Gout, unspecified
1.8
6.6
97
555
J94.8
ICD-10 Finland
Other specified pleural conditions
3.1
6.6
26
84
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
8.7
6.6
13
15
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.5
384
2991
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
6.5
82
448
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.4
6.5
41
171
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
6.5
86
478
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
5.3
6.5
18
34
R31
ICD-10 Finland
Unspecified haematuria
1.6
6.4
144
925
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.5
6.4
250
1810
D69.4
ICD-10 Finland
Other primary thrombocytopenia
70.1
6.4
7
*
C91
ICD-10 Finland
Lymphoid leukaemia
70.1
6.4
7
*
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
70.1
6.4
7
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
70.1
6.4
7
*
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
70.1
6.4
7
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
7.4
6.4
14
19
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
6.4
144
928
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.3
6.3
45
198
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.2
6.3
49
224
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.3
366
2844
188
Kela drug reimbursment
Psychosis requiring demanding treatment
3.9
6.3
18
47
S01.50
ICD-10 Finland
Open wound in oral cavity
3.9
6.3
18
47
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
18.1
6.3
9
5
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
18.1
6.3
9
5
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
6.3
6
*
C91.5
ICD-10 Finland
Adult T-cell lymphoma/leukaemia [HTLV-1-associated]
+∞
6.3
6
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
6.3
6
*
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
+∞
6.3
6
*
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
D73.5
ICD-10 Finland
Infarction of spleen
+∞
6.3
6
*
D73.0
ICD-10 Finland
Hyposplenism
+∞
6.3
6
*
2889X
ICD-9 Finland
Diseases of white blood cells, Unspecified disease of white blood cells
+∞
6.3
6
*
D73.1
ICD-10 Finland
Hypersplenism
+∞
6.3
6
*
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.7
6.2
33
126
174
Kela drug reimbursment
Ruxolitinib
26.8
6.2
8
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.2
6.2
52
245
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
6.2
313
2374
E000001, ,
ATC
1.4
6.2
260
1911
PE1AT
NOMESCO Finland
Femoral artery PTA
3.2
6.2
23
72
E66.8
ICD-10 Finland
Other obesity
1.9
6.2
72
384
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.0
6.1
67
349
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.9
6.1
28
99
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.1
525
4325
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.6
6.1
34
134
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.0
350
2715
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
2.7
6.0
30
111
N05AX08
ATC
risperidone; systemic
1.7
6.0
114
703

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
293
164
21.77
307.65
1.9
1.6
—
—
—
0
0
218
102
24.69
298.68
1.3
1.2
—
—
—
0
0
221
110
23.25
295.13
1.4
1.3
—
—
—
0
0
622
1403
6.71
283.17
5.6
2.5
1.79
1.79
%
0.04
586
1239
510
1041
6.80
254.56
6.0
2.6
73.07
69.84
e9/l
0.90
392
803
462
952
6.48
226.13
3.8
2.7
9.31
10.71
g/l
6.72
422
875
1212
5927
5.70
201.18
17.8
6.2
—
—
—
0
0
1213
5939
5.71
200.94
16.2
6.1
8.34
8.63
%
1.25
1169
5542
1209
5911
5.67
200.43
15.2
5.8
2.40
2.83
%
6.93
1167
5502
1188
5730
5.52
200.31
14.9
5.8
0.62
0.66
%
1.32
1146
5327
1222
6092
5.66
195.72
15.5
5.9
36.17
27.56
%
38.00
1173
5707
158
100
17.47
187.35
1.2
1.1
—
—
—
0
0
1193
6014
5.20
183.20
14.0
5.7
49.68
57.49
%
36.47
1145
5623
437
1025
5.54
182.65
9.1
4.1
0.81
0.92
%
0.35
318
344
194
184
11.90
181.56
6.3
3.1
0.91
1.27
%
0.58
181
166
367
745
6.14
179.55
2.2
1.8
1.56
1.45
g/l
0.20
325
692
148
101
16.09
168.48
3.6
2.4
1.80
1.17
e9/l
0.45
131
93
1199
6302
4.92
167.78
13.3
5.7
0.06
0.04
e9/l
0.99
1081
5427
401
935
5.43
167.63
9.0
4.0
0.47
0.62
%
0.90
290
299
1194
6289
4.85
165.71
13.3
5.7
0.74
0.58
e9/l
6.47
1073
5416
1216
6529
4.93
163.42
15.1
5.9
0.21
0.19
e9/l
2.08
1109
5707
1204
6462
4.80
160.68
13.7
5.8
5.69
1.96
e9/l
13.53
1118
5708
397
977
5.11
154.87
9.4
4.2
0.13
0.09
%
0.26
279
296
379
920
5.12
149.93
9.0
4.3
0.35
0.45
%
0.09
262
241
1243
7331
4.44
132.98
20.9
8.6
4.51
4.14
e9/l
2.78
1149
6378
382
1035
4.56
130.55
2.3
2.9
66.41
66.39
g/l
0.02
356
944
336
858
4.72
123.31
2.1
2.6
—
—
—
0
0
106
77
14.70
116.06
3.8
2.5
912.99
540.46
e6/l
0.48
85
68
255
565
5.20
110.43
2.4
1.8
1.29
1.53
g/l
3.55
217
487
1121
6612
3.48
109.37
10.8
6.0
10.51
11.54
umol/l
3.62
1086
6273
100
74
14.37
108.27
4.0
2.6
0.20
0.20
e9/l
0.12
85
67
120
131
9.84
100.73
9.2
3.4
—
—
—
0
0
133
178
8.08
94.89
1.4
1.2
57.77
50.02
u/l
0.13
120
156
108
113
10.19
93.44
6.6
3.0
42.60
54.32
%
3.39
92
101
147
234
6.83
89.66
1.3
1.4
—
—
—
0
0
129
180
7.72
88.70
4.8
2.1
—
—
—
0
0
959
5619
2.84
85.64
21.2
9.4
0.01
0.00
e9/l
1.83
820
4589
672
3281
2.84
85.57
5.2
2.7
2529.65
6222.07
umol/l
2.03
615
2856
134
212
6.82
82.09
1.4
1.4
107.56
125.69
u/ml
0.42
25
43
200
460
4.84
81.96
2.0
2.7
2.99
2.99
g/l
0.03
184
415
431
1695
3.13
80.78
3.3
2.5
22.73
22.76
%
0.01
382
1444
720
3728
2.73
80.61
7.3
3.9
7.39
7.40
ph
0.80
168
705
66
39
17.63
80.21
2.5
1.7
—
—
—
0
0
205
490
4.67
80.07
2.0
2.6
3.47
3.68
g/l
1.10
189
446
205
491
4.66
79.86
2.0
2.6
6.98
7.41
g/l
2.52
189
446
534
2416
2.84
77.10
1.9
1.5
2.12
2.47
g/l
4.50
392
1461
195
462
4.68
76.91
2.0
2.6
9.98
10.42
g/l
0.49
178
415
178
397
4.93
75.51
1.9
2.5
38.56
37.53
g/l
1.07
162
352
1009
6327
2.69
74.43
11.2
6.7
1.21
1.21
mmol/l
0.35
839
5394
439
1819
2.97
74.26
3.2
2.5
2.31
2.32
g/l
0.20
413
1680
461
1970
2.90
73.60
3.2
2.5
12.43
13.01
umol/l
0.88
436
1826
421
1713
3.00
73.51
8.7
5.7
1.04
1.03
mmol/l
0.43
400
1578
942
5747
2.62
72.98
10.3
6.1
1.21
1.21
mmol/l
0.41
887
5243
675
3524
2.62
72.40
6.9
4.3
—
—
—
0
0
900
5465
2.53
68.96
7.0
4.8
34.91
35.43
g/l
1.81
848
5090
618
3161
2.58
68.29
14.6
6.5
—
—
—
0
0
461
2053
2.77
67.24
6.0
3.4
0.81
0.82
mmol/l
0.39
440
1926
267
872
3.49
66.96
1.4
1.4
—
—
—
0
0
468
2118
2.73
65.97
1.7
1.8
—
—
—
0
0
164
386
4.63
64.91
2.4
3.9
1.16
1.64
ratio
0.50
12
34
165
394
4.57
64.12
2.4
3.9
47.00
67.27
mg/l
0.60
135
321
165
395
4.55
63.91
2.4
3.9
38.18
77.06
mg/l
0.65
134
324
127
250
5.44
61.94
5.5
3.7
49.94
58.27
%
4.46
127
250
1307
9799
3.07
60.55
15.3
7.3
82.89
78.17
u/l
3.05
1274
9219
155
380
4.42
58.12
1.3
1.3
—
—
—
0
0
120
238
5.38
57.99
1.3
1.3
249.64
272.08
u/ml
0.30
80
138
48
29
17.05
57.53
2.7
2.4
3446.88
253.33
e6/l
0.73
32
15
335
1369
2.84
56.53
1.5
1.5
—
—
—
0
0
49
32
15.78
56.45
2.6
1.8
—
—
—
0
0
145
367
4.25
52.04
2.9
2.7
3.66
3.66
g/l
0.01
140
346
127
292
4.65
51.52
2.4
4.2
—
—
—
0
0
50
40
12.88
51.38
1.1
1.1
—
—
—
0
0
275
1079
2.88
49.58
1.5
1.4
—
—
—
0
0
380
1758
2.54
49.40
1.6
1.6
—
—
—
0
0
64
78
8.51
49.03
2.6
2.7
35.25
42.00
%
0.92
28
40
1239
9407
2.55
49.01
6.6
4.0
14.72
12.24
mm/h
5.16
1180
8673
118
267
4.70
48.79
1.4
1.7
—
—
—
0
0
77
117
6.87
48.74
1.2
1.2
—
—
—
0
0
582
3263
2.25
48.67
2.9
2.2
3.25
2.97
mg/l
1.52
504
2744
329
1431
2.65
48.51
5.1
2.7
7.31
8.23
umol/l
0.29
295
1253
366
1679
2.54
48.32
1.5
1.3
554.36
476.70
titre
0.31
78
352
846
5515
2.17
48.17
4.1
2.8
213.42
126.31
ug/l
2.40
785
5061
79
126
6.55
47.75
2.3
2.5
—
—
—
0
0
576
3239
2.23
47.60
6.5
3.9
88.06
89.47
%
0.70
563
3160
405
1979
2.41
46.40
3.0
2.2
30.45
29.85
s
0.85
397
1916
1045
7477
2.21
45.89
7.3
4.9
6.67
6.73
mmol/l
0.44
1003
7009
592
3431
2.17
44.75
4.2
3.2
—
—
—
0
0
644
3864
2.14
44.44
4.4
3.3
100.92
82.75
e6/l
0.11
532
3002
483
2590
2.25
44.24
3.5
2.9
524.51
545.51
mosm/kgh2o
1.33
428
2221
664
4090
2.09
42.16
4.8
3.2
38.22
34.04
u/l
0.73
637
3885
593
3531
2.10
40.96
4.3
3.2
0.44
0.45
e6/l
0.01
489
2710
704
4518
2.02
39.10
5.1
3.8
74.48
105.80
e6/l
0.61
562
3223
472
2703
2.07
35.16
3.4
2.6
6.45
5.65
e6/l
0.20
431
2422
62
107
5.99
34.62
1.3
1.3
6.47
7.03
g/l
0.22
35
77
62
107
5.99
34.62
1.3
1.3
2.39
2.69
g/l
0.48
35
75
62
107
5.99
34.62
1.3
1.3
0.37
0.39
g/l
0.09
34
75
62
110
5.83
33.65
1.3
1.3
—
—
—
0
0
765
5234
1.91
33.55
2.4
2.0
93.38
94.56
pmol/l
0.32
447
2741
206
849
2.64
33.06
3.4
2.9
6.93
5.97
e9/l
0.26
164
691
258
1186
2.41
32.84
2.5
2.2
354.89
369.13
nmol/l
0.56
244
1087
80
182
4.58
32.76
1.4
1.6
0.72
0.84
g/l
0.32
50
139
837
5937
1.89
32.42
15.4
15.8
1.24
1.28
inr
0.54
295
1737
473
2797
1.99
31.66
2.2
1.8
1.11
1.22
mg/l
0.57
373
2130
45
63
7.33
30.62
3.2
2.7
1632.33
1195.95
u/ml
0.40
45
63
242
1134
2.34
29.29
10.5
7.6
10.46
9.81
mmol/l
0.69
230
1078
411
2380
1.99
28.79
2.1
1.7
1233.89
1185.77
nmol/l
0.46
335
1786
645
4333
1.83
28.56
4.0
3.3
2.34
2.35
mmol/l
0.68
589
3811
118
388
3.21
28.51
2.1
1.5
1.10
1.20
g/l
2.54
109
366
115
374
3.24
28.29
2.1
1.5
0.21
0.24
g/l
2.41
104
354
107
334
3.37
28.12
2.2
2.2
11.86
11.80
mg/l
0.02
100
306
598
3951
1.83
27.75
3.0
2.5
55.08
79.94
u/l
0.65
562
3651
489
3059
1.87
26.86
2.0
1.5
21.12
20.76
nmol/l
0.19
447
2580
108
351
3.23
26.58
6.4
4.2
1.54
1.56
mg/l
0.12
101
320
93
277
3.51
26.28
4.6
3.7
—
—
—
0
0
338
1883
2.02
26.12
2.4
2.1
—
—
—
0
0
728
5187
1.76
25.56
3.0
2.3
76.03
76.95
nmol/l
0.37
672
4635
1098
8820
1.83
25.25
5.9
4.3
—
—
—
0
0
127
473
2.83
24.61
3.0
2.3
21.55
21.62
s
0.05
121
423
1433
12689
2.61
24.49
30.8
14.3
23.25
24.78
mg/l
0.97
1264
10062
214
1035
2.24
23.78
5.7
3.6
1.21
1.23
mmol/l
3.28
194
891
401
2446
1.86
23.32
4.0
3.8
440.85
384.30
ng/l
0.15
322
1920
349
2049
1.91
22.80
3.7
3.0
2.77
2.37
e6/l
0.27
213
1152
1051
8449
1.75
22.77
5.9
4.4
251.70
2383.78
e6/l
1.86
27
122
563
3839
1.73
22.26
2.8
2.2
170.11
242.53
u/l
1.59
529
3608
27
30
9.14
22.11
1.0
1.0
—
—
—
0
0
26
6
43.99
21.44
1.2
1.0
—
—
—
0
0
85
277
3.19
20.82
4.8
4.3
2.48
2.54
mmol/l
0.06
57
184
215
1096
2.12
20.80
4.7
3.8
—
—
—
0
0
583
4074
1.69
20.70
4.7
2.3
—
—
—
0
0
166
765
2.31
20.59
1.7
1.3
326.10
233.75
u/ml
0.34
147
703
541
3724
1.69
20.22
3.3
3.0
1970.27
1408.34
ng/l
1.28
461
3178
1273
10990
1.87
19.80
37.5
16.9
15.32
14.94
%
1.75
1261
10781
231
1240
2.01
19.36
2.6
2.3
0.20
0.21
g/l
1.02
207
1166
1016
8262
1.66
19.34
4.1
3.1
63.32
49.32
u/l
2.25
954
7709
62
176
3.63
18.85
2.8
2.8
—
—
—
0
0
350
2170
1.79
18.78
3.7
2.8
0.74
1.25
e6/l
1.76
217
1266
67
201
3.44
18.74
2.6
3.1
—
—
—
0
0
265
1510
1.91
18.62
2.0
1.5
—
—
—
0
0
92
340
2.81
18.07
5.0
3.9
7.42
7.42
ph
0.24
85
300
296
1765
1.84
17.99
1.3
1.2
—
—
—
0
0
553
3923
1.64
17.89
3.4
3.1
—
—
—
0
0
70
223
3.24
17.81
1.3
1.2
—
—
—
0
0
77
262
3.04
17.54
3.8
2.5
14.74
16.23
%
2.21
44
146
680
5101
1.59
17.30
2.4
2.1
—
—
—
0
0
42
98
4.38
16.70
1.1
1.1
—
—
—
0
0
198
1064
1.99
16.43
12.0
9.1
—
—
—
0
0
258
1526
1.83
15.96
1.7
1.7
—
—
—
0
0
49
134
3.74
15.75
1.9
1.6
—
—
—
0
0
70
244
2.96
15.31
4.5
3.1
—
—
—
0
0
788
6226
1.54
15.25
6.2
4.9
0.00
0.00
estimate
0.50
212
1189
788
6236
1.53
15.07
4.5
3.6
0.00
0.00
estimate
0.75
216
1254
769
6058
1.53
14.99
4.3
2.5
—
—
—
0
0
95
396
2.49
14.70
5.2
3.1
—
—
—
0
0
330
2143
1.68
14.61
1.3
1.3
37.25
33.46
iu/ml
0.21
109
697
48
137
3.58
14.52
1.8
1.4
—
—
—
0
0
40
101
4.04
14.38
1.2
1.2
83.75
155.00
titre
—
8
18
56
178
3.23
14.34
1.7
1.4
32.99
31.95
g/l
0.22
48
159
75
282
2.74
14.29
3.3
2.2
116.90
130.45
g/l
3.39
52
216
1126
9699
1.58
14.17
4.5
4.0
14.79
14.77
pmol/l
0.09
1042
8796
357
2383
1.65
14.16
3.3
3.0
2.46
2.45
mmol/l
0.29
309
2093
26
25
10.56
13.74
1.3
1.1
—
—
—
0
0
110
505
2.27
13.72
3.0
1.8
2.36
1.88
ug/l
0.22
100
448
786
6295
1.50
13.70
4.6
3.6
0.02
0.01
estimate
0.28
194
1145
205
1182
1.85
13.66
7.3
3.7
1.91
1.94
mmol/l
0.04
179
964
1423
13098
2.00
13.41
31.5
16.6
139.35
139.65
mmol/l
4.31
1398
12751
630
4846
1.50
13.21
4.9
3.7
114.09
57.35
ng/l
0.33
464
3380
48
147
3.34
13.06
1.7
1.6
—
—
—
0
0
1424
13131
1.98
13.03
32.8
16.7
3.99
3.97
mmol/l
1.27
1396
12763
201
1175
1.82
12.78
2.9
2.4
33.13
81.48
u/l
0.61
178
987
201
1192
1.79
12.16
7.4
3.7
5.98
5.84
kpa
1.08
195
1156
21
17
12.50
12.12
1.1
1.4
—
—
—
0
0
158
870
1.91
12.11
6.9
3.8
7.41
7.41
ph
0.42
32
105
24
26
9.36
11.99
3.2
1.2
—
—
—
0
0
75
309
2.50
11.93
1.4
1.2
1.49
2.19
u/ml
—
9
31
306
2046
1.62
11.84
1.3
1.3
10.43
13.48
u/ml
0.43
93
774
45
142
3.23
11.70
1.6
1.4
215821.77
123770.05
e6/l
0.24
30
84
182
1060
1.81
11.68
2.9
3.0
261.65
211.13
ng/l
0.67
161
970
54
190
2.91
11.67
1.3
1.2
4.58
6.11
u/ml
0.27
24
81
75
313
2.47
11.61
1.4
1.2
3.43
8.22
u/ml
0.70
16
52
158
882
1.88
11.61
6.9
3.8
5.17
5.16
kpa
0.04
147
848
56
203
2.82
11.47
1.1
1.0
—
—
—
0
0
24
29
8.39
11.30
1.2
1.1
—
—
—
0
0
33
87
3.85
11.22
1.2
1.1
—
—
—
0
0
21
38
5.59
11.18
1.7
1.6
—
—
—
0
0
56
206
2.78
11.17
1.1
1.1
—
—
—
0
0
427
3117
1.51
11.11
4.4
2.2
—
—
—
0
0
1033
8933
1.46
11.02
4.6
3.8
—
—
—
0
0
458
3416
1.48
10.65
4.5
3.3
—
—
—
0
0
62
247
2.57
10.60
1.3
1.2
27.25
34.01
u/ml
—
8
20
631
5020
1.43
10.39
3.9
3.4
6.11
5.82
ph
0.88
31
355
40
129
3.16
10.07
1.3
1.1
—
—
—
0
0
227
1466
1.64
9.99
8.9
8.3
11.75
12.05
kpa
0.38
215
1406
227
1466
1.64
9.99
8.9
8.3
5.13
5.11
kpa
0.09
215
1404
1439
13492
1.87
9.91
20.8
10.2
26.83
26.31
u/l
0.41
1414
13012
53
204
2.65
9.72
1.3
1.3
—
—
—
0
0
166
995
1.75
9.64
5.2
3.8
91.19
86.23
ng/l
0.29
145
874
1280
11671
1.54
9.57
5.5
4.7
1.95
2.03
mu/l
0.28
1181
10646
46
166
2.82
9.54
1.6
1.3
1882.50
1599.33
e6/l
0.19
36
120
75
347
2.22
9.24
1.2
1.2
81.25
81.88
titre
—
8
32
103
541
1.97
9.09
1.5
1.2
—
—
—
0
0
373
2752
1.47
8.93
1.8
1.7
22186946.83
38720074.28
pmol/l
0.29
311
2265
223
1477
1.59
8.81
2.5
2.4
173.36
130.69
ug/g
0.59
174
1183
221
1464
1.59
8.73
9.2
8.3
0.96
1.14
mmol/l
0.24
179
1156
372
2757
1.46
8.67
1.3
1.3
1.56
1.49
u/ml
0.04
97
726
74
353
2.15
8.47
1.2
1.2
—
1290.83
—
0
12
20
45
4.49
8.37
1.6
1.4
—
—
—
0
0
18
37
4.91
8.37
2.1
1.6
—
—
—
0
0
72
342
2.16
8.34
1.3
1.2
—
—
—
0
0
22
54
4.12
8.27
1.4
1.2
—
—
—
0
0
236
1612
1.55
8.13
1.4
1.3
—
—
—
0
0
210
1403
1.57
7.97
1.3
1.3
—
—
—
0
0
126
739
1.77
7.89
3.0
3.5
4.52
4.56
pmol/l
0.06
107
653
37
133
2.83
7.78
1.8
1.3
—
—
—
0
0
119
691
1.78
7.71
1.5
1.2
—
—
—
0
0
23
62
3.75
7.64
1.4
1.3
—
—
—
0
0
117
680
1.78
7.56
10.0
11.8
—
—
—
0
0
15
17
8.90
7.54
5.1
3.5
—
—
—
0
0
157
1000
1.63
7.26
7.1
3.1
4.54
4.56
kpa
0.03
149
966
38
144
2.68
7.25
1.2
1.2
—
—
nmol/l
—
0
0
504
4042
1.36
7.25
3.6
3.2
7.24
7.54
mmol/l
0.74
421
3407
69
341
2.07
7.25
1.6
1.4
9.83
9.55
u/l
0.06
51
271
41
163
2.56
7.13
1.2
1.2
0.16
0.46
nmol/l
—
7
14
195
1320
1.55
6.97
9.7
8.7
94.69
95.52
%
0.94
184
1277
1402
13244
1.59
6.89
24.3
13.5
—
—
—
0
0
428
3373
1.37
6.80
5.0
4.0
0.00
0.01
estimate
1.28
195
1145
472
3779
1.36
6.78
3.6
3.3
965.46
277.77
mg/l
1.33
328
2455
71
364
2.00
6.77
1.4
1.5
284.89
277.99
ug/g
0.10
46
216
10
6
16.77
6.74
1.2
1.2
—
—
—
0
0
494
3989
1.35
6.69
4.4
3.9
12.95
8.59
mg/mmol
1.32
318
2548
35
133
2.67
6.67
1.6
2.2
—
—
—
0
0
136
856
1.65
6.60
2.2
2.4
12.02
23.04
au/ml
—
9
60
25
79
3.20
6.58
1.5
1.3
—
—
—
0
0
180
1224
1.53
6.30
1.7
1.5
—
—
—
0
0
133
844
1.63
6.26
5.0
5.5
—
—
—
0
0
36
144
2.54
6.21
1.4
1.4
417.21
351.54
pmol/l
0.31
29
126
37
150
2.50
6.21
1.3
1.2
—
—
—
0
0
47
214
2.23
6.11
2.9
2.9
—
—
—
0
0
16
39
4.13
6.09
1.0
1.1
—
—
—
0
0
18
49
3.70
5.93
1.1
1.1
—
—
—
0
0
16
30
5.38
5.85
1.3
1.6
74.39
107.40
nmol/24h
0.73
16
30
37
156
2.41
5.74
1.6
1.4
52.83
40.41
mu/l
0.31
32
141
34
138
2.50
5.72
1.6
1.4
274.14
280.76
mosm/kgh2o
0.99
29
100
176
1219
1.50
5.65
9.7
9.2
115.39
120.90
g/l
2.66
167
1191
18
51
3.56
5.61
1.8
2.2
53.97
55.46
ug/l
0.04
18
51
457
3727
1.32
5.60
4.5
3.9
—
—
—
0
0
16
42
3.84
5.54
1.1
1.1
—
—
—
0
0
47
224
2.13
5.49
1.6
1.3
60.33
61.49
mmol/l
0.07
39
187
90
536
1.72
5.41
1.4
1.4
22.80
27.85
iu/l
0.87
77
451
13
21
6.23
5.38
3.0
2.2
39.62
120.57
u/l
0.50
13
21
52
261
2.03
5.32
3.4
1.5
—
—
—
0
0
1246
11661
1.34
5.06
6.7
5.8
40.07
39.91
mmol/mol
0.23
1146
10779
16
45
3.58
5.05
1.9
1.6
—
—
—
0
0
16
45
3.58
5.05
2.5
2.7
—
—
—
0
0
54
281
1.95
5.01
4.9
2.5
—
—
—
0
0
34
148
2.33
4.96
9.9
7.5
7.35
7.37
mmol/l
0.01
27
126
14
28
5.04
4.94
1.7
1.8
—
—
—
0
0
426
3493
1.30
4.93
1.6
1.4
—
—
—
0
0
34
149
2.31
4.89
1.5
1.2
—
—
—
0
0
31
133
2.36
4.68
1.9
2.5
1.13
1.22
g/24h
0.07
14
66
180
1304
1.43
4.60
2.9
4.2
16.48
19.73
ug/l
0.09
142
1060
37
173
2.17
4.58
1.2
1.2
—
—
—
0
0
13
27
4.85
4.50
1.8
1.4
—
185.33
—
0
6
31
138
2.27
4.33
3.1
1.5
—
—
—
0
0
24
95
2.55
4.31
1.3
1.4
—
—
—
0
0
141
988
1.47
4.30
1.2
1.2
—
—
—
0
0
67
1090
0.60
4.18
1.3
1.3
—
—
—
0
0
9
13
6.95
4.16
2.4
1.8
—
—
—
0
0
26
109
2.41
4.15
1.0
1.1
—
—
—
0
0
131
915
1.47
4.07
1.6
1.4
—
—
—
0
0
18
63
2.88
4.07
1.2
1.6
—
—
—
0
0
13
31
4.22
4.01
6.5
3.8
—
—
—
0
0
1297
12315
1.32
3.98
5.1
4.5
6.09
5.96
mmol/l
2.15
1181
11168
22
87
2.55
3.97
10.2
3.7
—
—
—
0
0
83
529
1.60
3.92
2.5
2.7
—
—
—
0
0
13
32
4.09
3.90
1.3
1.2
114.99
42.87
ug/l
—
7
15
23
94
2.47
3.89
1.5
1.1
—
—
—
0
0
31
145
2.16
3.88
1.2
1.1
—
—
—
0
0
10
19
5.29
3.83
1.2
1.3
—
—
—
0
0
352
2903
1.27
3.78
4.0
3.6
—
—
—
0
0
97
648
1.53
3.75
7.8
3.9
—
—
—
0
0
1457
14123
1.49
3.68
45.3
20.9
249.32
249.00
e9/l
0.04
1428
13748
30
142
2.13
3.66
1.1
1.2
—
—
—
0
0
1457
14127
1.48
3.63
45.1
20.8
91.95
91.02
fl
8.42
1440
13909
1456
14116
1.48
3.63
45.5
21.0
39.07
40.05
%
7.62
1368
13170
1457
14128
1.48
3.62
45.1
20.8
30.35
30.31
pg
0.32
1439
13908
1457
14128
1.48
3.62
45.3
20.9
11.43
6.75
e9/l
26.00
1420
13707
1457
14129
1.48
3.61
45.3
20.9
4.33
4.48
e12/l
18.39
1421
13714
1457
14133
1.48
3.56
45.6
21.0
129.95
135.11
g/l
26.47
1438
13913
7
9
7.81
3.56
4.4
2.0
268.57
140.78
ug/g
—
7
9
83
543
1.56
3.54
2.0
1.8
—
—
—
0
0
52
302
1.75
3.51
1.8
1.7
8023.40
14621.22
e6/l
0.98
35
230
29
138
2.12
3.50
8.6
3.3
—
—
—
0
0
130
935
1.43
3.49
2.7
2.1
11.73
12.33
nmol/l
0.37
111
827
24
106
2.28
3.46
6.6
1.5
10.29
10.99
%
0.36
24
106
17
404
0.41
3.44
32.8
10.0
—
—
—
0
0
22
94
2.36
3.41
1.3
1.1
—
—
—
0
0
24
107
2.26
3.39
1.7
2.3
619.57
625.41
ml
0.02
14
69
12
32
3.77
3.39
1.3
1.2
—
—
—
0
0
118
840
1.44
3.36
1.3
1.2
46.00
152.98
iu/ml
5.77
35
339
10
23
4.37
3.31
2.5
2.3
15.73
17.87
umol/l
—
10
23
20
83
2.43
3.31
1.5
2.2
532.17
490.50
min
0.69
12
58
17
65
2.63
3.30
1.1
1.1
1.07
1.07
ratio
—
9
26
34
178
1.93
3.20
2.5
2.0
—
—
—
0
0
11
29
3.81
3.18
1.2
1.2
—
—
—
0
0
19
79
2.42
3.14
1.2
1.1
—
—
—
0
0
41
230
1.80
3.14
2.0
1.2
—
—
—
0
0
12
35
3.45
3.10
1.8
1.6
—
—
—
0
0
31
159
1.97
3.10
1.7
1.6
53.32
60.26
%
0.38
21
104
27
132
2.06
3.07
1.8
2.2
17.38
6.44
umol/l
0.52
14
94
22
99
2.24
3.06
1.1
1.5
13.89
13.58
umol/l
0.05
22
94
6
8
7.52
3.05
1.3
1.4
—
—
—
0
0
71
469
1.54
2.95
2.9
3.7
0.35
0.27
g/l
0.42
40
201
163
1254
1.33
2.94
7.1
4.1
—
—
—
0
0
57
359
1.61
2.90
1.2
1.3
199.85
224.64
miu/ml
0.21
20
171
18
76
2.38
2.89
1.4
1.7
—
—
—
0
0
50
306
1.66
2.85
2.7
1.7
—
—
—
0
0
82
563
1.48
2.85
8.5
4.1
24.70
24.86
mmol/l
0.20
77
532
45
269
1.69
2.80
4.9
2.4
—
—
—
0
0
8
18
4.46
2.79
2.8
1.0
—
—
—
0
0
8
18
4.46
2.79
2.8
1.0
—
—
—
0
0
8
18
4.46
2.79
2.8
1.0
—
—
—
0
0
64
420
1.55
2.75
1.6
1.7
—
—
—
0
0
34
189
1.82
2.72
5.2
5.1
414.64
361.19
umol/l
1.28
28
167
12
40
3.01
2.69
2.0
1.2
20.07
33.84
%
1.06
12
35
12
40
3.01
2.69
1.2
1.4
—
—
—
0
0
10
29
3.46
2.69
2.3
1.9
—
—
—
0
0
391
3377
1.21
2.68
1.8
1.6
1.61
1.37
mmol/l
3.20
326
2838
30
162
1.87
2.63
1.4
1.5
0.19
0.33
nmol/l
1.93
25
131
47
290
1.64
2.62
3.7
1.6
311.00
533.84
e6/l
0.23
39
232
24
121
2.00
2.56
1.5
1.4
19146.08
156052.01
e6/l
0.97
13
84
5
7
7.16
2.55
1.2
1.9
1.80
1.93
%
—
5
7
13
50
2.61
2.53
2.4
1.3
—
—
—
0
0
82
580
1.44
2.48
1.1
1.1
—
125.50
titre
—
0
12
47
295
1.61
2.47
3.1
1.5
3.69
3.80
mmol/l
0.27
41
280
15
64
2.36
2.39
1.7
1.5
—
—
—
0
0
46
290
1.60
2.38
3.7
1.5
10.72
21.52
e6/l
0.40
36
224
7
17
4.13
2.36
1.7
1.8
—
—
—
0
0
89
647
1.40
2.33
2.7
2.4
—
—
—
0
0
13
53
2.47
2.28
1.2
1.1
64.40
275.07
ng/l
—
5
14
8
23
3.49
2.27
1.3
1.1
—
—
—
0
0
49
318
1.56
2.26
1.7
1.9
3.97
5.41
iu/l
0.50
19
110
7
18
3.90
2.25
1.7
3.4
—
—
—
0
0
19
93
2.06
2.22
1.9
2.1
—
—
—
0
0
5
9
5.57
2.21
1.0
1.4
—
—
—
0
0
6
14
4.30
2.15
4.5
10.4
4.83
6.12
mmol/l
—
6
14
7
19
3.70
2.15
1.6
3.7
—
—
—
0
0
25
137
1.84
2.14
1.4
1.6
—
—
—
0
0
21
109
1.94
2.11
2.5
2.0
1.50
2.16
u/field
—
8
45
48
318
1.53
2.05
2.4
2.3
102.79
97.71
ug/min
0.04
28
196
15
70
2.15
1.98
1.0
1.0
—
—
—
0
0
7
21
3.34
1.96
1.3
1.4
—
—
—
0
0
57
396
1.46
1.95
6.6
7.6
1.16
1.37
mmol/l
1.70
45
351
57
396
1.46
1.95
2.7
1.9
—
—
—
0
0
56
388
1.46
1.95
1.3
1.2
—
—
—
0
0
5
11
4.56
1.94
1.2
1.3
—
—
—
0
0
6
16
3.76
1.93
2.0
1.3
40.33
100.63
ng/l
—
6
16
54
372
1.47
1.93
2.7
1.9
—
—
—
0
0
57
399
1.44
1.89
2.7
1.9
—
—
—
0
0
7
22
3.19
1.88
2.0
1.2
—
—
—
0
0
24
136
1.78
1.87
5.4
1.7
—
—
—
0
0
57
400
1.44
1.87
2.7
1.9
—
—
—
0
0
50
713
0.69
1.82
1.6
1.4
—
—
—
0
0
14
66
2.13
1.82
3.4
3.6
7.43
7.42
ph
—
5
20
33
207
1.61
1.80
1.6
1.3
—
—
—
0
0
41
271
1.53
1.80
6.6
3.8
26.05
27.15
mg/l
0.08
28
172
55
388
1.43
1.76
1.7
2.1
12354.94
3679.52
u/l
0.40
16
160
14
67
2.10
1.76
4.2
2.6
—
—
—
0
0
12
54
2.23
1.74
2.0
3.5
86.17
99.06
umol/l
—
6
31
65
475
1.38
1.72
2.8
3.4
10.73
3001.55
u/ml
0.81
60
407
5
13
3.85
1.71
1.2
1.3
—
—
—
0
0
15
75
2.01
1.69
1.0
1.0
—
—
—
0
0
84
641
1.33
1.69
4.1
3.6
—
—
—
0
0
31
197
1.59
1.63
1.5
1.1
—
—
—
0
0
55
395
1.41
1.62
2.7
1.8
—
—
—
0
0
58
424
1.38
1.55
1.7
1.7
229.51
308.40
mu/l
2.74
53
383
44
618
0.70
1.51
1.4
1.7
—
—
—
0
0
101
805
1.27
1.50
8.9
7.9
25.22
24.38
mmol/l
1.17
93
769
6
21
2.86
1.50
1.0
1.0
—
—
—
0
0
10
45
2.23
1.46
1.0
1.1
2107.90
1646.67
miu/ml
—
10
45
20
117
1.72
1.45
1.7
1.4
21.75
31.11
%
0.48
11
76
6
22
2.73
1.43
1.0
1.2
2.31
1.87
umol/24h
—
6
22
99
793
1.27
1.43
1.2
1.2
—
—
—
0
0
127
1052
1.23
1.37
1.5
1.6
—
—
—
0
0
12
223
0.53
1.37
1.8
1.4
—
—
—
0
0
0
38
0.00
1.34
0.0
1.0
—
0.90
—
0
18
11
54
2.04
1.33
13.8
15.7
—
—
—
0
0
6
24
2.51
1.30
1.0
3.1
—
—
—
0
0
8
34
2.36
1.29
1.1
2.5
—
—
—
0
0
8
35
2.29
1.27
1.0
2.5
—
—
—
0
0
12
217
0.55
1.27
1.8
1.4
—
—
—
0
0
8
36
2.23
1.24
1.3
1.4
—
—
—
0
0
17
100
1.71
1.23
1.1
1.3
0.14
0.66
u/ml
—
7
56
25
163
1.54
1.23
3.1
2.6
—
—
—
0
0
29
196
1.49
1.22
1.6
1.1
—
—
—
0
0
30
205
1.47
1.20
2.0
1.5
—
—
—
0
0
6
26
2.31
1.18
2.2
1.7
—
—
—
0
0
12
64
1.88
1.18
1.2
1.2
—
—
—
0
0
33
231
1.44
1.18
1.9
1.6
—
—
—
0
0
39
282
1.39
1.17
7.2
8.8
11.06
11.40
mmol/l
0.23
34
258
39
282
1.39
1.17
7.2
8.8
105.85
105.34
mmol/l
0.27
34
258
14
79
1.78
1.17
2.2
1.5
—
—
—
0
0
67
531
1.27
1.10
6.0
6.0
2.03
1.62
%
1.10
61
501
43
321
1.35
1.08
2.6
2.5
—
—
—
0
0
13
218
0.59
1.08
1.8
1.4
—
—
—
0
0
99
825
1.21
1.06
3.8
2.9
—
—
—
0
0
19
121
1.58
1.05
1.0
1.2
—
—
—
0
0
6
125
0.48
1.04
1.0
1.0
—
0.39
—
0
42
128
1095
1.18
1.04
2.3
2.4
7.00
7.02
ug/l
0.01
106
974
65
522
1.26
0.98
6.2
6.1
0.90
0.89
%
0.15
59
493
37
275
1.35
0.98
3.1
3.1
0.80
0.84
nmol/l
0.23
29
214
26
182
1.44
0.96
1.4
1.2
—
—
—
0
0
0
32
0.00
0.95
0.0
1.0
—
15.41
—
0
23
17
109
1.57
0.93
5.6
5.0
19.05
70.85
u/ml
—
6
35
6
27
2.23
0.93
9.2
6.7
—
—
—
0
0
91
1079
0.83
0.93
4.8
3.4
—
—
—
0
0
25
175
1.44
0.93
1.5
1.4
33.94
23.23
u/l
0.70
18
145
1298
12744
1.11
0.83
5.2
4.9
2.58
2.73
mmol/l
7.23
1203
11704
60
491
1.23
0.81
1.1
1.1
—
—
—
0
0
1225
12000
1.10
0.80
4.4
3.9
1.42
1.29
mmol/l
6.06
1131
10940
1275
12514
1.10
0.80
4.7
4.4
4.41
4.62
mmol/l
9.84
1188
11566
43
339
1.28
0.79
4.5
4.5
—
—
—
0
0
0
27
0.00
0.77
0.0
1.0
—
2.43
—
0
22
12
75
1.60
0.75
2.8
2.8
—
—
—
0
0
9
57
1.58
0.71
1.3
3.1
—
—
—
0
0
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
7
44
1.59
0.65
1.1
1.0
—
3.04
—
0
5
1262
12425
1.08
0.60
4.7
4.4
1.34
1.46
mmol/l
17.27
1168
11408
27
214
1.27
0.52
1.1
1.3
—
—
—
0
0
9
64
1.41
0.51
9.2
7.7
—
—
—
0
0
154
1416
1.10
0.49
1.6
1.7
—
—
—
0
0
7
48
1.46
0.46
1.9
2.3
—
—
—
0
0
19
243
0.78
0.46
1.4
1.7
—
—
—
0
0
26
210
1.24
0.45
1.1
1.1
0.23
3.17
u/ml
3.53
15
114
5
32
1.56
0.42
1.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
6.78
—
0
6
8
59
1.36
0.41
1.1
1.3
141.38
170.13
mmol/24h
—
8
59
0
17
0.00
0.40
0.0
1.9
—
3.37
—
0
7
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
12
88
1.37
0.40
1.3
1.5
0.96
1.00
g/l
0.23
12
88
9
66
1.37
0.38
2.7
3.0
—
—
—
0
0
146
1561
0.93
0.36
4.1
4.5
31.86
32.35
%
0.21
109
1055
24
288
0.83
0.35
1.4
1.3
—
—
—
0
0
49
432
1.14
0.35
1.1
1.1
—
—
—
0
0
9
72
1.25
0.25
1.0
1.3
1.44
1.55
g/l
—
9
72
12
97
1.24
0.23
2.2
1.4
93.92
81.47
umol/l
0.50
12
97
247
2553
0.96
0.21
3.0
3.1
0.74
0.76
ug/l
0.14
168
1693
446
4361
1.03
0.21
4.8
5.0
2.08
2.72
ug/l
1.40
390
3895
0
12
0.00
0.21
0.0
1.0
—
257.60
—
0
5
0
12
0.00
0.21
0.0
1.0
—
1.52
—
0
7
6
48
1.25
0.20
1.0
1.1
—
—
—
0
0
6
50
1.20
0.19
1.0
1.4
—
—
—
0
0
37
337
1.10
0.19
1.1
1.1
—
—
—
0
0
450
4425
1.02
0.15
3.3
2.8
—
—
—
0
0
25
274
0.91
0.13
1.2
1.2
—
—
—
0
0
54
513
1.05
0.11
6.1
4.8
—
—
—
0
0
106
1089
0.97
0.08
1.4
1.4
—
—
—
0
0
16
175
0.91
0.08
1.1
1.1
3.46
1.80
u/ml
—
10
89
5
63
0.79
0.08
2.0
1.3
—
—
—
0
0
13
142
0.91
0.06
2.2
2.6
—
—
—
0
0
13
141
0.92
0.05
1.5
2.1
—
—
—
0
0
15
139
1.08
0.05
2.3
1.4
—
—
—
0
0
275
2777
0.99
0.05
5.0
4.0
1.01
1.02
kg/l
1.05
43
409
1069
10714
0.99
0.03
40.0
18.3
329.88
332.46
g/l
14.92
1060
10625
18
182
0.99
0.00
1.1
1.1
0.07
0.88
u/ml
—
8
78
19
189
1.01
0.00
1.1
1.1
2.23
5.75
u/ml
—
9
93
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
212.58
—
0
5
0
5
0.00
0.00
0.0
1.8
—
4.76
—
0
5
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
3.0
—
—
—
0
0
7
76
0.92
-0.00
1.9
1.2
184.30
166.86
pmol/l
—
7
76
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint D3_WHITEBLOODCELLNAS and mortality.

Females

Parameter HR [95% CI] p-value
D3_WHITEBLOODCELLNAS 2.642 [2.33, 3.0] < 0.001
Birth year 0.991 [0.98, 1.0] 0.036

During the follow-up period (1.1.1998 — 31.12.2019), 1292 out of 4517 females with D3_WHITEBLOODCELLNAS died.

Males

Parameter HR [95% CI] p-value
D3_WHITEBLOODCELLNAS 2.552 [2.21, 2.94] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 1504 out of 4168 males with D3_WHITEBLOODCELLNAS died.

Mortality risk

Mortality risk for people of age

years, who have D3_WHITEBLOODCELLNAS.

N-year risk Females Males
1 0.209% 0.51%
5 1.386% 2.595%
10 3.304% 6.39%
15 6.409% 12.203%
20 10.995% 20.185%

Relationships between endpoints

↥

Index endpoint: D3_WHITEBLOODCELLNAS – Other and unspecified disorders of white blood cells

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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