Respiratory tuberculosis, not confirmed

AB1_RESP_TUBERCU_NONCONF

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A16
  • Hospital discharge: ICD-9 01[1-2]
  • Hospital discharge: ICD-8 01[1-2]
  • Hospital discharge: excluded ICD-9 01[1-2].A
  • Cause of death: ICD-10 A16
  • Cause of death: ICD-9 01[1-2]
  • Cause of death: ICD-8 01[1-2]
  • Cause of death: excluded ICD-9 01[1-2].A

2 out of 7 registries used, show all original rules.

1697

4. Check minimum number of events

None

1697

5. Include endpoints

None

1697

6. Filter based on genotype QC (FinnGen only)

1639

Control definitions (FinnGen only)

Control exclude
AB1_TUBERCULOSIS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26949 10715 15412
Only index persons 12955 6283 6672
Unadjusted period prevalence (%)
Whole population 0.39 0.31 0.43
Only index persons 0.24 0.23 0.25
Median age at first event (years)
Whole population 49.87 48.85 50.29
Only index persons 38.41 38.00 38.81

-FinnGen-

Key figures

All Female Male
Number of individuals 1639 576 1063
Unadjusted period prevalence (%) 0.39 0.20 0.49
Median age at first event (years) 40.76 32.89 45.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1697
Matched controls
16970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
+∞
307.7
394
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
279.1
260
*
01220
ICD-8 Finland
Other respiratory tuberculosis, Pleurisy with effusion without mention of cause
+∞
215.3
202
*
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
2048.4
183.7
175
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
43.9
178.9
107
26
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
154.6
146
*
01210
ICD-8 Finland
Other respiratory tuberculosis, Tuberculosis pleurae, pleuritis exsudativa tuberculosa
+∞
132.0
125
*
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
49.7
91.2
53
11
0110K, ,
ICD-8 Finland
+∞
74.5
71
*
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
+∞
70.3
67
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.1
66.5
336
1261
0110X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, EPÄILTY]
+∞
65.0
62
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.3
63.9
277
948
A16.5
ICD-10 Finland
Tuberculous pleurisy, without mention of bacteriological or histological confirmation
+∞
59.7
57
*
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
12.6
56.7
56
46
A16.1
ICD-10 Finland
Tuberculosis of lung, bacteriological and histological examination not done
+∞
48.1
46
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.4
46.1
381
1807
0110J, ,
ICD-8 Finland
+∞
45.0
43
*
A16.9
ICD-10 Finland
Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
+∞
41.8
40
*
0120X
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, EPÄILTY]
+∞
38.7
37
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
37.6
36
*
0110A, ,
ICD-8 Finland
+∞
35.5
34
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
32.4
31
*
R03BB04
ATC
tiotropium bromide; inhalant
2.2
31.8
296
1457
01104
ICD-8 Finland
Pulmonary tuberculosis, Tuberculoma pulmonum
+∞
30.3
29
*
01106
ICD-8 Finland
Pulmonary tuberculosis, Pulmonum alia sive NUD
+∞
29.2
28
*
0119X
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, EPÄILTY]
+∞
29.2
28
*
01109
ICD-8 Finland
Pulmonary tuberculosis, Unspecified
+∞
27.2
26
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
26.4
396
2314
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
7.7
25.1
35
46
01297
ICD-8 Finland
Other respiratory tuberculosis, Suspecta
+∞
25.1
24
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.4
23.2
165
719
R03DA04
ATC
theophylline; systemic, rectal
2.2
21.3
188
899
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
20.4
614
4335
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.7
20.2
109
415
R03BB01
ATC
ipratropium bromide; inhalant
2.3
19.9
152
683
H02AB06
ATC
prednisolone; systemic
1.6
19.1
788
5980
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.6
18.3
60
170
01710
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum colli
+∞
17.7
17
*
1240
FHL
Bronchoscopy
3.8
17.7
55
150
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.0
17.1
190
991
51120
ICD-8 Finland
Pleurisy, Other specified forms of effusion, except tuberculous
50.5
17.0
20
*
J45.8
ICD-10 Finland
Mixed asthma
3.1
15.8
67
223
R03AC12
ATC
salmeterol; inhalant
2.3
15.7
123
558
0120B
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, HISTOLOGISESTI VARMENNETTU]
+∞
15.6
15
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
15.4
275
1669
TGC00
NOMESCO Finland
Bronchial lavation
3.2
15.3
60
191
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.1
15.0
151
758
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.4
14.3
99
425
J96.1
ICD-10 Finland
Chronic respiratory failure
2.8
14.3
72
265
R03AC02
ATC
salbutamol; inhalant
1.5
14.2
769
6059
48509
ICD-8 Finland
Bronchopneumonia, unspecified
5.5
14.0
27
50
48609
ICD-8 Finland
Pneumonia, unspecified
4.5
13.8
33
74
J47
ICD-10 Finland
Bronchiectasis
3.4
13.7
50
152
01908
ICD-8 Finland
Late effects of tuberculosis, Sequelae aliae o tuberculosis organorum respirationis
+∞
13.6
13
*
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
+∞
13.6
13
*
0118X
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, EPÄILTY]
+∞
13.6
13
*
A15.6
ICD-10 Finland
Tuberculous pleurisy, confirmed bacteriologically and histologically
+∞
13.6
13
*
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
34.3
13.5
17
5
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
2.7
12.9
72
279
M05BA04
ATC
alendronic acid; oral
1.9
12.7
169
935
01292
ICD-8 Finland
Other respiratory tuberculosis, Lymphonodorum tracheobronchialium et mediastini
+∞
12.5
12
*
A70
ICPC
Tuberculosis
130.9
12.4
13
*
13597
ICD-8 Finland
Sarcoidosis, Suspecta
6.1
12.1
21
35
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
8.7
12.0
25
29
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
4.2
12.0
31
74
48601
ICD-8 Finland
More specifically, unspecified pneumonia and the pleural irritation caused by it
10.6
11.8
22
21
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
11.7
89
399
0112X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, EPÄILTY]
+∞
11.5
11
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
11.5
11
*
51899
ICD-8 Finland
Bronchiectasis
12.8
11.1
19
15
L04AA13
ATC
[U] leflunomide
3.4
11.1
40
121
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
4.5
11.0
26
58
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
8.9
10.8
22
25
132
Kela drug reimbursment
Sarcoidosis
4.8
10.7
24
51
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
10.4
279
1872
01103
ICD-8 Finland
Pulmonary tuberculosis, Bronchialis
+∞
10.4
10
*
03199
ICD-8 Finland
Other diseases due to Mycobacteria, Other and unspecified
+∞
10.4
10
*
R03BB02
ATC
oxitropium bromide; inhalant
3.6
10.3
34
97
J01MA14
ATC
moxifloxacin; systemic
1.8
10.2
157
909
R05CB01
ATC
acetylcysteine; inhalant, oral
2.9
10.2
48
171
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
10.0
223
1429
J43.9
ICD-10 Finland
Emphysema, unspecified
2.8
9.7
47
170
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
55.3
9.7
11
*
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
3.1
9.5
38
123
13599
ICD-8 Finland
Sarcoidosis, Unspecified
7.2
9.5
22
31
R03BA01
ATC
beclometasone; inhalant
1.6
9.4
216
1395
Y0499
ICD-8 Finland
Investigation of respiratory system
3.3
9.3
35
109
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
9.1
160
963
J94.9
ICD-10 Finland
Pleural condition, unspecified
4.8
9.1
20
42
L04AX01
ATC
azathioprine; systemic
2.4
9.0
58
242
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.0
8.9
90
454
51109
ICD-8 Finland
Pleurisy, Sicca NUD
20.1
8.5
12
6
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
8.4
109
600
A16.8
ICD-10 Finland
Other respiratory tuberculosis, without mention of bacteriological or histological confirmation
+∞
8.3
8
*
01202, ,
ICD-8 Finland
+∞
8.3
8
*
0110B, ,
ICD-8 Finland
+∞
8.3
8
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.0
8.3
35
117
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.6
8.3
48
191
A98
ICPC
Health maint/preventive medicine
0.7
8.2
1088
12030
N05CD07
ATC
temazepam; oral
1.5
8.1
261
1820
P01BA02
ATC
hydroxychloroquine; oral
1.9
8.0
107
594
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
4.3
7.9
20
47
49300
ICD-8 Finland
Asthma, bronchiale
2.5
7.9
48
196
A02BC01
ATC
omeprazole; systemic
1.4
7.7
439
3403
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.7
7.6
40
152
5111B
ICD-9 Finland
Pleurisy, With effusion, with mention of a bacterial cause other than tuberculosis[PLEURITIS EXSUDATIVA ALIA DEFINITA]
25.1
7.6
10
*
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
3.5
7.6
25
72
H02AB07
ATC
prednisone; oral
1.5
7.5
233
1612
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
2.9
7.5
33
114
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
80.4
7.4
8
*
J01FA06
ATC
roxithromycin; oral
1.3
7.4
571
4641
A07EC01
ATC
sulfasalazine; oral, rectal
1.8
7.3
104
588
A10BA02
ATC
metformin; oral
0.7
7.3
281
3791
A16.4
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation
+∞
7.3
7
*
R03BA02
ATC
budesonide; inhalant
1.5
7.3
243
1705
J46
ICD-10 Finland
Status asthmaticus
2.5
7.3
43
173
A02BA02
ATC
ranitidine; systemic
1.4
7.1
342
2571
R95
ICPC
Chron obstructive pulmonary disease
2.2
7.1
60
283
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
6.9
82
438
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
3.7
6.9
21
57
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
40.2
6.8
8
*
R04.2
ICD-10 Finland
Haemoptysis
2.0
6.7
71
366
49109
ICD-8 Finland
Chronic bronchitis, Unspecified
5.5
6.6
18
33
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
12.3
6.6
11
9
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
14.4
6.4
10
7
L01BA01
ATC
methotrexate; systemic
2.1
6.3
54
256
0116X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA, EPÄILTY]
+∞
6.3
6
*
01105
ICD-8 Finland
Pulmonary tuberculosis, Disseminata pulmonum
+∞
6.3
6
*
01904
ICD-8 Finland
Late effects of tuberculosis, Adhaesiones pleurae
+∞
6.3
6
*
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
6.3
6
*
01230
ICD-8 Finland
Other respiratory tuberculosis, Tuberculous laryngitis
+∞
6.3
6
*
R03AC13
ATC
formoterol; inhalant
1.8
6.2
86
485

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
58
209
2.84
11.98
3.3
2.6
—
—
—
0
0
53
192
2.82
10.87
5.4
2.6
—
—
—
0
0
984
11072
0.74
8.53
5.2
5.3
2.62
2.57
mmol/l
0.85
883
9901
1117
12276
0.74
7.81
32.2
25.6
39.28
39.17
%
0.22
1006
11210
1118
12275
0.74
7.67
32.0
25.4
248.20
239.22
e9/l
4.06
1075
11827
1119
12279
0.74
7.60
32.1
25.6
131.49
132.33
g/l
1.01
1090
11963
1119
12278
0.74
7.58
31.9
25.5
7.21
6.95
e9/l
2.13
1073
11779
1119
12277
0.74
7.57
32.0
25.4
4.36
4.38
e12/l
0.58
1070
11780
1119
12276
0.74
7.56
31.8
25.3
30.38
30.44
pg
0.49
1088
11962
1119
12276
0.74
7.56
31.9
25.4
91.85
91.75
fl
0.30
1088
11963
1040
11509
0.75
7.28
20.1
16.9
—
—
—
0
0
960
10742
0.76
7.27
4.7
4.7
4.50
4.44
mmol/l
1.19
864
9681
1081
11881
0.75
7.06
25.6
20.7
84.60
85.56
umol/l
0.32
1081
11876
1095
11955
0.76
6.34
25.3
20.9
139.52
139.60
mmol/l
0.50
1064
11561
1097
11972
0.76
6.32
25.5
21.0
4.01
4.01
mmol/l
0.09
1064
11563
956
10620
0.77
6.31
4.6
4.6
1.44
1.43
mmol/l
0.44
854
9466
923
10274
0.78
6.03
4.1
4.2
1.30
1.28
mmol/l
0.38
816
9072
998
10980
0.78
5.80
4.9
5.0
6.07
6.11
mmol/l
0.36
891
9684
958
10549
0.79
5.35
6.2
6.4
40.54
41.03
mmol/mol
0.93
867
9518
1094
11846
0.78
5.21
13.3
11.0
25.53
25.10
u/l
0.08
1042
11268
228
3024
0.72
5.18
2.7
3.3
0.92
0.84
ug/l
0.30
154
2130
33
139
2.40
5.15
1.9
1.7
0.79
0.91
g/l
0.18
23
106
15
34
4.44
4.74
1.1
1.4
—
—
—
0
0
151
1052
1.48
4.70
1.7
1.6
—
—
—
0
0
217
1664
1.35
3.92
6.5
7.0
1.52
1.23
mmol/l
0.52
179
1292
216
1659
1.35
3.87
6.2
7.0
11.56
11.65
kpa
0.09
206
1570
216
1659
1.35
3.87
6.2
7.0
5.17
5.08
kpa
0.52
206
1569
120
832
1.48
3.86
1.6
1.4
—
—
—
0
0
452
5285
0.80
3.86
4.5
5.4
3.06
4.60
ug/l
1.04
388
4631
140
1003
1.43
3.80
4.0
4.8
—
—
—
0
0
21
83
2.55
3.80
2.3
1.3
7.88
7.15
g/l
0.35
16
59
21
83
2.55
3.80
2.3
1.3
2.54
2.72
g/l
0.20
15
59
21
83
2.55
3.80
2.3
1.3
0.49
0.44
g/l
0.24
16
58
12
29
4.16
3.70
1.2
1.3
—
—
—
0
0
21
85
2.49
3.63
2.2
1.3
—
—
—
0
0
52
302
1.74
3.51
2.0
2.2
122.61
126.07
g/l
0.52
38
228
945
10217
0.83
3.49
4.8
4.6
1.93
2.04
mu/l
1.93
841
9046
28
132
2.14
3.46
1.3
1.2
27.09
15.83
u/l
0.88
23
121
1060
11319
0.83
3.32
23.8
17.6
27.94
27.80
mg/l
0.04
908
9291
113
812
1.42
3.07
3.2
2.8
10.32
10.83
g/l
0.61
104
735
77
514
1.52
3.03
1.4
1.2
265.38
211.05
u/ml
0.25
69
463
874
9416
0.85
2.74
25.9
20.8
15.44
15.40
%
0.08
859
9180
188
1496
1.29
2.65
7.0
7.3
94.85
95.15
%
0.26
179
1437
90
639
1.43
2.64
2.1
1.9
1.07
1.95
ug/l
0.75
76
549
230
1878
1.26
2.63
2.5
2.0
—
—
—
0
0
34
191
1.80
2.63
1.4
1.4
—
—
—
0
0
118
884
1.36
2.54
5.0
3.9
0.76
0.74
%
0.02
47
325
161
1266
1.30
2.50
1.4
1.3
595.29
464.66
titre
0.35
34
279
123
931
1.35
2.49
7.9
6.8
25.10
24.40
mmol/l
1.12
117
887
265
3138
0.82
2.42
2.9
3.2
—
—
—
0
0
58
388
1.51
2.33
2.9
3.4
24.98
25.19
mmol/l
0.13
58
381
130
1003
1.32
2.33
4.9
3.9
0.91
0.96
%
0.07
57
390
12
47
2.56
2.27
1.0
1.0
1.77
3.14
u/ml
—
5
18
357
4086
0.84
2.26
3.5
3.7
14.36
9.43
mg/mmol
0.59
221
2608
340
3898
0.84
2.19
4.5
4.3
—
—
—
0
0
837
8962
0.87
2.18
30.3
23.3
330.49
331.22
g/l
1.38
823
8828
15
67
2.25
2.18
1.1
1.3
2.15
0.74
u/ml
—
10
38
336
3852
0.84
2.16
2.9
3.2
520.47
265.08
mg/l
0.45
216
2499
178
1453
1.25
2.08
2.2
1.8
—
—
—
0
0
621
5676
1.15
2.01
7.5
5.4
0.04
0.04
e9/l
0.15
552
4821
619
5662
1.15
1.98
7.5
5.4
0.64
0.62
e9/l
1.03
549
4806
639
5866
1.14
1.93
7.8
5.6
0.19
0.20
e9/l
0.66
578
5067
778
8316
0.88
1.85
4.6
4.3
—
—
—
0
0
765
8184
0.88
1.84
6.1
5.0
6054.94
1952.99
e6/l
0.30
17
159
346
3906
0.86
1.82
3.2
3.1
7.05
7.17
mmol/l
0.20
283
3207
15
73
2.06
1.80
4.4
2.6
—
—
—
0
0
43
287
1.51
1.80
1.9
2.1
10.77
12.47
mg/l
0.60
43
262
118
943
1.27
1.68
5.2
4.0
0.13
0.12
%
0.10
45
331
505
5521
0.88
1.67
3.1
2.7
—
—
—
0
0
6
19
3.17
1.66
1.7
1.4
—
—
—
0
0
9
186
0.48
1.62
1.6
1.7
—
—
—
0
0
16
84
1.91
1.60
2.3
2.4
—
—
—
0
0
75
569
1.33
1.58
1.6
1.4
—
—
—
0
0
625
5789
1.13
1.58
7.7
5.5
1.81
1.89
e9/l
0.54
564
5043
511
5556
0.89
1.53
2.2
2.1
92.22
92.26
pmol/l
0.01
265
2893
5
15
3.34
1.52
4.2
2.6
—
—
—
0
0
83
645
1.30
1.50
2.2
1.8
1.60
1.62
g/l
0.01
74
579
20
117
1.72
1.45
1.1
1.4
—
—
—
0
0
5
16
3.13
1.44
1.4
1.1
—
—
—
0
0
63
827
0.75
1.43
2.1
2.2
11.09
11.77
nmol/l
0.26
55
716
42
295
1.43
1.42
2.7
2.9
—
—
—
0
0
239
2721
0.86
1.41
1.2
1.3
—
—
—
0
0
108
876
1.25
1.40
5.5
4.0
0.06
0.46
%
0.66
34
273
46
330
1.40
1.40
1.2
1.2
1.53
1.13
u/ml
—
9
28
48
347
1.39
1.39
2.6
3.0
7.72
7.69
kpa
0.04
48
341
44
315
1.41
1.36
4.0
3.8
—
—
—
0
0
626
6685
0.90
1.33
3.9
3.1
51.78
55.81
u/l
0.40
579
6054
133
1111
1.21
1.32
4.1
3.4
—
—
—
0
0
81
1016
0.79
1.31
4.8
4.1
—
—
—
0
0
780
8229
0.90
1.30
5.5
4.6
—
—
—
0
0
159
1356
1.19
1.28
2.1
1.4
—
—
—
0
0
33
228
1.46
1.24
2.6
3.7
0.52
1.74
%
3.08
27
199
569
5303
1.11
1.24
8.1
6.0
—
—
—
0
0
258
2889
0.87
1.22
1.6
1.6
1.36
1.33
mmol/l
0.18
220
2362
8
37
2.17
1.21
3.4
2.3
16.89
240.44
ug/l
—
8
31
32
222
1.45
1.19
1.5
1.4
1704.14
1650.97
e6/l
0.05
22
161
12
64
1.88
1.18
1.1
1.1
—
—
—
0
0
0
36
0.00
1.14
0.0
1.2
—
92.82
—
0
26
269
2986
0.88
1.12
1.9
1.8
1143.75
1182.67
nmol/l
0.33
203
2194
20
304
0.65
1.09
1.4
1.5
—
—
—
0
0
44
329
1.35
1.09
1.2
1.2
—
—
—
0
0
5
21
2.38
1.09
6.0
5.1
—
—
—
0
0
12
66
1.82
1.09
1.7
1.8
68.33
72.46
%
0.43
12
61
14
81
1.73
1.09
7.9
1.3
—
—
—
0
0
22
145
1.52
1.06
1.2
1.1
—
—
—
0
0
623
6594
0.91
1.05
18.5
19.7
1.31
1.39
inr
1.18
183
1814
27
187
1.45
1.04
1.4
1.2
—
—
—
0
0
39
519
0.75
1.03
1.3
1.2
88.26
148.94
iu/ml
0.99
11
182
16
98
1.64
1.03
7.1
1.3
—
—
—
0
0
790
8267
0.92
1.03
3.8
3.8
15.15
15.07
pmol/l
0.37
696
7274
91
755
1.22
1.02
7.3
9.9
—
—
—
0
0
439
4077
1.10
1.02
5.9
4.4
—
—
—
0
0
10
53
1.89
1.01
1.2
1.0
0.18
0.83
u/ml
—
5
26
23
155
1.49
1.01
1.0
1.1
—
—
—
0
0
9
48
1.88
1.00
1.6
1.3
—
—
—
0
0
28
197
1.43
1.00
1.5
1.4
26071.82
84511.84
e6/l
1.03
17
121
575
5414
1.09
0.99
8.5
6.0
8.93
8.95
%
0.03
539
4993
12
69
1.74
0.96
13.7
1.6
—
—
—
0
0
0
32
0.00
0.95
0.0
1.2
—
157.43
—
0
7
0
32
0.00
0.95
0.0
1.1
—
0.73
—
0
19
26
183
1.43
0.94
1.2
1.3
—
—
—
0
0
150
1317
1.15
0.90
2.7
2.5
4.25
6.23
ug/l
2.39
125
1113
230
2078
1.12
0.89
3.6
3.1
0.81
0.81
mmol/l
0.17
206
1927
572
5409
1.09
0.89
7.9
5.6
58.33
58.78
%
0.36
537
5003
40
307
1.31
0.87
1.4
1.2
—
—
—
0
0
582
5511
1.09
0.87
8.2
5.9
25.67
25.70
%
0.03
546
5095
16
103
1.56
0.87
7.2
1.3
—
—
—
0
0
16
103
1.56
0.87
7.1
1.3
—
—
—
0
0
8
43
1.86
0.87
1.0
1.0
—
—
—
0
0
6
31
1.94
0.84
1.3
1.9
—
—
—
0
0
6
31
1.94
0.84
1.8
1.5
—
—
—
0
0
14
88
1.60
0.84
7.0
3.2
7.42
7.42
ph
—
6
27
711
7426
0.93
0.83
5.7
5.0
6.88
6.88
mmol/l
0.03
673
7006
8
46
1.74
0.82
1.0
1.0
—
—
—
0
0
12
73
1.65
0.81
1.2
1.1
1.79
1.37
u/ml
—
7
36
218
1978
1.12
0.80
2.5
2.5
2.23
2.25
g/l
0.35
203
1809
381
3557
1.09
0.80
3.9
3.1
36.37
36.02
u/l
0.03
356
3361
69
574
1.21
0.79
5.3
4.3
—
—
—
0
0
6
33
1.82
0.79
1.3
1.4
—
—
—
0
0
23
315
0.73
0.78
1.4
1.6
8091.50
15528.78
e6/l
0.53
12
231
22
157
1.41
0.76
1.1
1.4
138.60
110.15
u/ml
—
5
25
0
28
0.00
0.76
0.0
3.5
—
14.48
—
0
23
9
53
1.70
0.75
11.4
1.4
—
—
—
0
0
12
75
1.60
0.75
1.8
2.7
38.17
39.99
%
—
6
47
12
75
1.60
0.75
1.0
1.2
—
—
—
0
0
106
923
1.16
0.74
1.6
1.5
—
—
—
0
0
7
38
1.85
0.73
1.0
1.1
—
—
—
0
0
141
1254
1.14
0.73
6.1
6.4
11.62
11.54
mmol/l
0.04
135
1182
317
2948
1.09
0.73
8.6
6.6
—
—
—
0
0
30
390
0.77
0.73
1.1
1.1
—
163.44
—
0
9
36
281
1.29
0.73
1.9
1.4
0.23
0.24
g/l
0.40
36
270
551
5244
1.08
0.72
8.2
5.6
0.66
0.64
%
0.21
517
4823
103
898
1.16
0.71
3.8
3.7
7.43
7.40
ph
2.41
14
110
566
5394
1.07
0.71
8.1
5.6
2.85
2.83
%
0.06
530
4971
691
6633
1.07
0.70
11.0
8.6
4.39
4.31
e9/l
0.32
616
5732
152
1363
1.13
0.70
3.7
3.1
205.64
269.56
ng/l
1.70
142
1250
9
58
1.55
0.69
1.1
1.2
187.00
378.17
u/l
—
9
52
381
4046
0.92
0.68
4.4
3.5
77.71
89.49
e6/l
0.18
316
3209
104
912
1.15
0.67
3.8
3.7
5.17
5.19
kpa
0.07
98
857
15
102
1.47
0.67
7.5
1.3
—
—
—
0
0
427
4512
0.93
0.67
2.3
2.3
—
—
—
0
0
288
2679
1.09
0.67
4.8
4.1
195.78
302.06
ng/l
0.93
245
2311
19
136
1.40
0.67
1.1
1.1
230.74
98.13
iu/ml
—
5
24
17
120
1.42
0.64
1.1
1.2
126.86
223.06
miu/ml
—
7
40
312
3332
0.92
0.64
1.6
1.6
20.37
20.10
nmol/l
0.11
262
2799
149
1344
1.12
0.64
4.6
3.5
1.82
2.05
mmol/l
0.34
122
1085
26
336
0.77
0.63
1.0
1.2
—
—
—
0
0
25
190
1.32
0.63
1.4
1.5
—
—
—
0
0
435
4577
0.93
0.61
5.0
4.0
121.17
122.85
e6/l
0.01
341
3424
281
3005
0.92
0.60
4.7
3.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
1.87
—
0
20
456
4787
0.94
0.60
3.1
2.7
142.35
156.22
ug/l
0.56
402
4279
99
875
1.14
0.59
1.9
1.6
—
—
—
0
0
204
1880
1.10
0.59
2.6
2.5
21.86
21.90
%
0.01
175
1579
11
72
1.53
0.59
2.5
1.9
—
43.07
—
0
6
160
1459
1.11
0.58
3.4
3.9
73.69
21.85
ug/l
0.49
137
1213
6
35
1.72
0.57
1.2
1.2
—
—
—
0
0
6
35
1.72
0.57
1.5
1.1
—
—
—
0
0
103
916
1.13
0.57
1.7
1.5
—
—
—
0
0
12
81
1.48
0.57
2.4
2.3
—
—
—
0
0
38
461
0.82
0.55
2.3
2.5
38.49
37.05
g/l
0.96
32
393
13
90
1.45
0.55
2.0
1.4
—
32.29
—
0
7
19
142
1.34
0.54
2.7
2.7
—
—
—
0
0
16
116
1.38
0.54
1.1
1.6
—
—
—
0
0
63
726
0.86
0.53
1.2
1.2
—
—
—
0
0
18
237
0.76
0.52
1.5
1.5
—
—
—
0
0
241
2254
1.08
0.51
3.2
3.0
1.51
1.16
e6/l
0.70
153
1341
293
3105
0.93
0.51
5.0
4.0
87.58
83.44
%
2.03
285
3027
22
171
1.29
0.50
1.6
1.4
—
—
—
0
0
24
189
1.27
0.49
1.6
1.4
—
—
—
0
0
21
268
0.78
0.49
1.0
1.1
—
—
—
0
0
97
873
1.12
0.47
4.0
3.1
122.37
125.63
g/l
0.78
97
852
336
3532
0.94
0.47
4.3
3.4
—
—
—
0
0
26
209
1.25
0.46
1.2
1.2
—
—
—
0
0
78
875
0.89
0.46
4.3
3.3
—
—
—
0
0
83
741
1.13
0.46
3.2
3.2
11.47
6.43
e9/l
0.37
58
557
284
3000
0.94
0.46
3.0
2.4
—
—
—
0
0
125
1143
1.10
0.46
2.6
2.3
31.26
34.88
u/l
0.67
99
954
18
138
1.31
0.45
1.7
1.3
28.12
28.61
iu/l
0.02
13
114
14
103
1.36
0.45
6.0
1.3
—
—
—
0
0
20
157
1.28
0.43
1.1
1.0
—
—
—
0
0
5
31
1.61
0.43
36.8
18.8
1430.80
1628.58
nmol/l
—
5
31
19
240
0.79
0.42
1.3
1.7
—
—
—
0
0
65
576
1.13
0.42
1.4
1.3
—
—
—
0
0
20
158
1.27
0.41
3.2
4.2
—
—
—
0
0
289
2746
1.06
0.41
4.4
3.9
—
—
—
0
0
38
323
1.18
0.41
4.8
4.7
3.34
2.77
mmol/l
0.49
28
219
0
15
0.00
0.41
0.0
1.2
—
7.63
—
0
9
228
2151
1.07
0.41
2.6
2.5
11.93
12.00
umol/l
0.05
216
1980
58
511
1.14
0.41
2.4
2.2
273.73
508.51
ug/l
1.09
52
479
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
89
981
0.90
0.40
1.5
1.5
—
—
—
0
0
29
346
0.84
0.39
3.3
2.6
—
—
—
0
0
7
103
0.68
0.39
2.4
2.9
—
—
—
0
0
18
142
1.27
0.38
1.2
1.3
—
—
—
0
0
11
80
1.38
0.38
1.3
1.2
—
—
—
0
0
12
89
1.35
0.38
8.7
2.4
—
—
—
0
0
29
344
0.84
0.37
2.1
2.3
91.70
79.65
ug/min
0.06
18
206
353
3678
0.95
0.37
4.1
3.4
0.47
0.53
e6/l
0.22
292
2895
9
69
1.31
0.37
5.3
1.6
8.22
10.17
mmol/l
—
9
69
15
116
1.30
0.37
1.1
1.1
—
—
—
0
0
13
169
0.77
0.37
1.5
1.8
191.54
216.86
pmol/l
0.63
13
155
27
226
1.20
0.36
1.6
1.3
30.55
755.82
e6/l
0.88
20
185
27
226
1.20
0.36
1.6
1.2
27.21
48.83
e6/l
0.25
19
178
12
90
1.34
0.35
1.8
1.1
—
—
—
0
0
5
76
0.66
0.35
1.0
1.3
—
—
—
0
0
13
99
1.32
0.35
1.4
1.2
—
—
—
0
0
254
2419
1.06
0.35
1.9
1.6
1.35
1.46
mg/l
0.20
200
1893
14
108
1.30
0.35
1.1
1.1
—
—
—
0
0
44
386
1.14
0.34
2.1
1.8
21.41
21.68
s
0.15
39
355
17
211
0.80
0.34
2.8
2.7
—
—
—
0
0
12
156
0.77
0.34
3.2
2.1
—
—
—
0
0
32
372
0.86
0.34
17.8
13.2
—
—
—
0
0
13
100
1.30
0.33
1.3
1.4
—
—
—
0
0
16
127
1.26
0.33
1.1
1.2
—
—
—
0
0
126
1175
1.08
0.33
2.1
2.1
0.20
0.20
g/l
0.09
119
1083
6
90
0.67
0.32
3.8
2.4
8.73
7.23
mmol/l
—
6
57
6
90
0.67
0.32
1.5
1.8
9.25
10.74
%
—
6
90
125
1168
1.08
0.31
8.5
7.6
—
—
—
0
0
193
1831
1.06
0.31
5.5
5.2
1.08
1.03
mmol/l
1.11
173
1663
381
3941
0.96
0.31
3.0
2.5
—
—
—
0
0
465
4515
1.04
0.30
4.2
3.7
5.80
5.80
ph
0.00
23
200
7
54
1.30
0.30
1.9
4.1
51.64
51.07
%
—
7
48
563
5772
0.96
0.30
4.8
4.0
0.00
0.00
estimate
0.50
103
1052
24
203
1.18
0.30
1.8
2.9
—
—
—
0
0
97
1043
0.93
0.29
2.4
2.5
—
—
—
0
0
17
206
0.82
0.29
1.5
1.5
—
—
—
0
0
536
5228
1.04
0.28
4.3
4.3
38.48
57.63
ng/l
1.67
401
4036
918
9319
0.97
0.27
9.1
7.5
77.92
81.34
u/l
2.08
851
8646
18
215
0.84
0.27
1.7
1.6
2.82
4.68
iu/l
—
8
66
663
6497
1.03
0.26
6.8
6.0
10.81
12.37
umol/l
3.77
624
6114
38
338
1.13
0.26
1.6
1.6
—
—
—
0
0
5
71
0.70
0.26
4.4
1.5
—
—
—
0
0
166
1582
1.05
0.25
1.2
1.2
—
—
—
0
0
91
973
0.93
0.25
2.0
2.1
351.27
374.29
nmol/l
0.55
79
872
73
676
1.08
0.25
4.2
2.5
1.26
1.15
%
0.43
73
671
10
78
1.28
0.24
5.7
3.2
—
—
—
0
0
15
124
1.21
0.24
1.5
1.2
1.71
5.73
u/ml
—
7
52
6
85
0.70
0.24
1.3
1.2
—
—
—
0
0
34
303
1.12
0.23
4.6
2.5
—
—
—
0
0
16
134
1.20
0.23
2.4
2.0
4.50
2.27
u/field
—
8
41
192
1843
1.05
0.23
1.7
1.4
3.03
2.70
g/l
0.70
113
1041
136
1294
1.06
0.22
2.2
2.4
65.40
67.56
e9/l
0.41
108
1020
556
5671
0.97
0.22
5.1
4.8
34.07
34.42
g/l
0.68
500
5227
20
231
0.86
0.22
1.5
2.0
—
—
—
0
0
300
2911
1.04
0.22
3.3
2.7
5.95
4.71
e6/l
0.87
275
2629
0
11
0.00
0.21
0.0
1.1
—
0.30
—
0
5
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
5.2
—
0.31
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
561
5718
0.97
0.21
4.8
4.0
0.00
0.00
estimate
0.99
113
1179
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.62
—
0
5
254
2623
0.96
0.21
3.3
3.1
2.46
2.46
mmol/l
0.05
218
2284
133
1394
0.95
0.21
2.4
2.6
6.86
9.40
umol/l
1.82
111
1224
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
75.86
—
0
5
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
131
1249
1.05
0.21
1.3
1.3
—
—
—
0
0
586
5966
0.97
0.20
6.6
6.0
1.21
1.21
mmol/l
0.01
514
5366
435
4254
1.03
0.20
4.1
3.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
7.40
—
0
8
50
541
0.92
0.19
4.7
4.0
24.88
24.95
mmol/l
0.05
45
491
559
5689
0.97
0.19
6.2
5.4
0.00
0.00
estimate
-0.00
101
1070
109
1038
1.05
0.18
3.2
3.7
85.46
98.14
ng/l
1.15
93
876
6
53
1.13
0.18
4.2
2.6
785.17
1615.26
u/ml
—
6
53
7
60
1.17
0.17
1.3
1.0
—
—
—
0
0
51
474
1.08
0.17
3.7
2.9
0.31
0.29
g/l
0.08
25
180
42
387
1.09
0.17
5.0
4.3
7.42
7.42
ph
0.57
37
340
263
2560
1.03
0.17
5.6
4.4
1.02
1.02
kg/l
0.07
45
414
198
2044
0.96
0.17
1.2
1.2
1.17
1.61
u/ml
0.55
63
498
661
6517
1.02
0.17
7.3
6.8
1.21
1.21
mmol/l
0.66
553
5474
321
3285
0.97
0.17
3.2
2.8
3753.08
8136.13
umol/l
1.02
267
2761
8
68
1.18
0.16
1.0
1.0
—
—
—
0
0
391
3833
1.03
0.16
2.6
2.5
57.22
81.04
u/l
0.58
361
3506
61
648
0.94
0.16
3.9
2.8
—
—
—
0
0
493
5013
0.98
0.16
12.4
10.2
0.00
0.00
e9/l
0.10
407
4049
126
1310
0.96
0.16
3.6
4.5
—
—
—
0
0
32
293
1.09
0.15
2.1
2.6
15.35
15.57
%
0.12
21
153
148
1532
0.96
0.15
1.3
1.4
—
—
—
0
0
43
400
1.08
0.15
3.0
3.1
0.78
0.84
nmol/l
0.52
37
316
128
1234
1.04
0.14
2.6
2.7
65.77
65.99
g/l
0.12
114
1105
7
88
0.79
0.14
11.6
15.5
—
—
—
0
0
292
2982
0.97
0.14
1.7
1.8
23744743.02
10429360.51
pmol/l
0.23
219
2378
276
2820
0.97
0.13
3.6
3.1
528.09
547.40
mosm/kgh2o
0.96
240
2414
30
325
0.92
0.13
3.7
3.5
7.93
7.84
mmol/l
0.07
30
319
69
657
1.05
0.13
4.2
2.5
0.66
0.65
%
0.07
69
652
71
677
1.05
0.13
1.3
1.3
—
—
—
0
0
37
396
0.93
0.12
3.5
3.6
—
—
—
0
0
31
334
0.93
0.12
1.6
1.4
—
—
—
0
0
32
344
0.93
0.12
3.5
3.4
1.62
1.71
mmol/l
0.31
32
337
480
4738
1.02
0.11
2.3
2.2
81.48
78.81
nmol/l
1.08
414
4091
361
3554
1.02
0.11
2.3
2.2
3.02
3.12
mg/l
0.38
302
2965
15
134
1.12
0.11
1.1
1.2
—
—
—
0
0
159
1629
0.97
0.10
1.3
1.2
65.34
39.66
iu/ml
0.43
48
510
5
45
1.11
0.09
1.2
1.7
—
—
—
0
0
15
135
1.11
0.09
4.7
3.2
—
—
—
0
0
70
727
0.96
0.09
4.3
3.9
—
—
—
0
0
433
4382
0.98
0.09
3.3
3.4
2.34
2.35
mmol/l
0.37
373
3770
5
46
1.09
0.09
1.4
1.5
0.29
0.15
nmol/l
—
5
34
23
248
0.93
0.09
1.7
1.5
—
—
—
0
0
849
8541
0.99
0.08
5.7
4.1
16.29
14.72
mm/h
1.74
777
7739
38
399
0.95
0.08
1.1
1.3
—
—
—
0
0
112
1093
1.03
0.08
3.8
3.6
1.22
1.22
mmol/l
0.25
95
932
14
127
1.10
0.08
1.1
1.2
—
—
nmol/l
—
0
0
6
71
0.84
0.07
1.0
1.2
—
4.50
—
0
18
108
1054
1.03
0.07
1.4
1.4
—
—
—
0
0
21
225
0.93
0.07
1.2
1.3
—
—
—
0
0
40
418
0.96
0.07
1.4
1.4
—
—
—
0
0
9
88
1.02
0.07
2.1
2.0
3.08
1.89
ug/l
—
9
72
43
413
1.04
0.06
4.2
4.8
—
—
—
0
0
9
100
0.90
0.06
1.8
1.2
—
—
—
0
0
64
659
0.97
0.06
4.2
3.8
—
—
—
0
0
51
526
0.97
0.05
2.4
3.2
147.66
8032.34
u/ml
0.87
43
449
395
3919
1.01
0.05
2.5
2.2
207.74
227.29
u/l
0.23
365
3640
11
100
1.10
0.05
1.1
1.1
—
—
—
0
0
20
189
1.06
0.04
1.5
1.2
41.00
47.56
u/ml
—
6
15
26
271
0.96
0.04
1.2
1.1
—
—
—
0
0
154
1558
0.99
0.04
1.3
1.2
18.41
14.74
u/ml
0.26
64
544
452
4496
1.01
0.03
3.5
3.2
1738.33
2007.81
ng/l
0.61
397
3874
51
522
0.98
0.03
1.3
1.2
—
—
—
0
0
17
161
1.06
0.03
1.2
1.3
—
—
—
0
0
52
509
1.02
0.03
2.5
2.0
—
—
—
0
0
16
152
1.05
0.02
2.5
2.2
0.56
1.48
g/24h
—
8
75
73
720
1.01
0.02
2.5
2.5
—
—
—
0
0
11
117
0.94
0.01
1.0
1.2
—
—
—
0
0
12
127
0.94
0.01
1.3
1.2
—
—
—
0
0
14
133
1.05
0.01
1.1
1.2
—
—
—
0
0
14
147
0.95
0.01
1.1
1.2
0.63
0.64
nmol/l
0.04
14
137
72
712
1.01
0.01
1.5
1.7
1.44
1.55
g/l
0.54
60
606
49
497
0.99
0.01
4.1
3.5
108.54
70.48
mg/l
0.18
40
408
215
2157
1.00
0.00
3.6
3.2
2.42
1.90
e6/l
0.49
126
1250
35
344
1.02
0.00
1.9
1.6
—
—
—
0
0
49
496
0.99
0.00
4.1
3.5
43.83
67.83
mg/l
1.00
40
405
14
145
0.97
0.00
1.5
2.0
—
—
—
0
0
16
165
0.97
0.00
1.2
1.4
—
—
—
0
0
49
485
1.01
0.00
4.0
3.5
2.16
1.73
ratio
—
6
35
106
1058
1.00
0.00
2.4
2.1
182.94
142.20
ug/g
0.44
83
831
55
548
1.00
0.00
2.6
2.5
9.64
10.47
g/l
0.76
49
477
32
318
1.01
0.00
3.9
3.7
31.24
28.62
mg/l
0.13
22
215
17
167
1.02
0.00
1.8
1.3
16.91
8.59
u/l
1.09
12
131
18
177
1.02
0.00
1.1
1.1
—
—
—
0
0
22
223
0.99
0.00
1.0
1.1
—
—
—
0
0
316
3163
1.00
0.00
5.2
4.3
0.00
0.00
estimate
0.50
94
1009
391
3907
1.00
0.00
4.6
4.0
7.40
7.40
ph
0.13
71
730
37
367
1.01
0.00
4.4
3.7
—
—
—
0
0
0
8
0.00
0.00
0.0
5.4
—
—
—
0
0
5
56
0.89
0.00
2.0
2.4
1063.80
846.83
e6/l
—
5
46
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
8
84
0.95
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
69
1.01
-0.00
2.0
1.1
—
—
—
0
0
8
89
0.90
-0.00
1.1
1.8
—
—
—
0
0
5
52
0.96
-0.00
2.4
3.0
24.40
32.19
umol/l
—
5
37
9
89
1.01
-0.00
2.2
2.0
4.17
2.98
ug/l
—
9
80
5
58
0.86
-0.00
1.6
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
15.4
—
215.29
—
0
7
35
350
1.00
-0.00
1.5
1.5
237.82
269.17
ug/g
0.44
22
204
0
7
0.00
-0.00
0.0
4.4
—
—
—
0
0
9
91
0.99
-0.00
1.0
1.1
—
—
—
0
0
177
1770
1.00
-0.00
2.3
2.3
1.83
1.78
%
0.24
149
1547
9
91
0.99
-0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_RESP_TUBERCU_NONCONF and mortality.

Females

Parameter HR [95% CI] p-value
AB1_RESP_TUBERCU_NONCONF 2.647 [2.24, 3.13] < 0.001
Birth year 0.993 [0.98, 1.0] 0.118

During the follow-up period (1.1.1998 — 31.12.2019), 641 out of 1245 females with AB1_RESP_TUBERCU_NONCONF died.

Males

Parameter HR [95% CI] p-value
AB1_RESP_TUBERCU_NONCONF 2.682 [2.28, 3.16] < 0.001
Birth year 0.988 [0.98, 1.0] 0.014

During the follow-up period (1.1.1998 — 31.12.2019), 1179 out of 1955 males with AB1_RESP_TUBERCU_NONCONF died.

Mortality risk

Mortality risk for people of age

years, who have AB1_RESP_TUBERCU_NONCONF.

N-year risk Females Males
1 0.247% 0.493%
5 1.684% 3.329%
10 3.933% 8.096%
15 6.764% 15.062%
20 12.124% 24.76%

Relationships between endpoints

Index endpoint: AB1_RESP_TUBERCU_NONCONF – Respiratory tuberculosis, not confirmed

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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