pulmonary tuberculosis: A bacterial infection that affects the lungs and is caused by Mycobacterium tuberculosis. Most patients with tuberculosis do not have symptoms (latent tuberculosis) and are not contagious. When signs and symptoms occur (active tuberculosis), patients become contagious. The signs and symptoms include chronic cough with blood-tinged sputum, night sweats, fever, fatigue, and weight loss.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
2316 |
6. Filter based on genotype QC (FinnGen only) |
2316 |
Control definitions (FinnGen only)
- Control exclude
- IBD_TUBERCULOSIS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Respiratory tuberculosis
based on the number of shared cases.
Similar with more cases:
- Respiratory tuberculosis, confirmed and not-confirmed
- Tuberculosis
- Tuberculosis, IBD comorbidity
- Tuberculosis, wide
- Infections, IBD-co-morbidities
Similar with less cases:
- Respiratory tuberculosis, confirmed and not-confirmed
- Respiratory tuberculosis, not confirmed
- Respiratory TBC, ICD-8 codes not specifying whether confirmed bacteriologically or histologically
- Respiratory tuberculosis, bacteriologically and histologically confirmed
- Respiratory tuberculosis, confirmed
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 34910 | 13713 | 20113 |
| Only index persons | 17505 | 8163 | 9342 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.51 | 0.39 | 0.56 |
| Only index persons | 0.33 | 0.30 | 0.36 |
| Median age at first event (years) | |||
| Whole population | 53.02 | 52.55 | 53.15 |
| Only index persons | 42.73 | 41.60 | 43.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2316 | 804 | 1512 |
| Unadjusted period prevalence (%) | 0.53 | 0.27 | 0.67 |
| Median age at first event (years) | 45.55 | 37.14 | 50.03 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2155
- Matched controls
- 21549
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
+∞
323.0
372
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
294.7
276
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
260.8
245
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
209.9
198
*
01220
ICD-8 Finland
Other respiratory tuberculosis, Pleurisy with effusion without mention of cause
+∞
193.7
183
*
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
+∞
171.1
162
*
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
143.3
136
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
39.4
121.1
154
42
01210
ICD-8 Finland
Other respiratory tuberculosis, Tuberculosis pleurae, pleuritis exsudativa tuberculosa
+∞
119.9
114
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.8
98.8
486
1532
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.2
94.7
406
1128
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
+∞
78.6
75
*
0110K
ICD-8 Finland
NA
+∞
71.2
68
*
A70
ICPC
Tuberculosis
+∞
70.2
67
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
64.9
62
*
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
+∞
60.7
58
*
0110X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, EPÄILTY]
+∞
58.6
56
*
A16.5
ICD-10 Finland
Tuberculous pleurisy, without mention of bacteriological or histological confirmation
+∞
57.5
55
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
56.0
496
2240
A15.6
ICD-10 Finland
Tuberculous pleurisy, confirmed bacteriologically and histologically
+∞
50.2
48
*
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
+∞
47.0
45
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
46.5
803
4888
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
26.3
42.5
59
23
0110J
ICD-8 Finland
NA
+∞
41.8
40
*
A16.1
ICD-10 Finland
Tuberculosis of lung, bacteriological and histological examination not done
+∞
41.8
40
*
R03BB04
ATC
tiotropium bromide; inhalant
2.5
41.0
376
1701
A16.9
ICD-10 Finland
Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
+∞
39.7
38
*
A15.3
ICD-10 Finland
Tuberculosis of lung, confirmed by unspecified means
+∞
34.5
33
*
0110A
ICD-8 Finland
NA
+∞
34.5
33
*
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
18.1
34.1
53
30
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.0
34.0
217
787
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.0
33.8
506
2838
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
12.3
33.0
60
50
0120X
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, EPÄILTY]
+∞
32.4
31
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.5
31.7
159
486
A15.7
ICD-10 Finland
Primary respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
30.3
29
*
0119X
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, EPÄILTY]
+∞
29.2
28
*
01104
ICD-8 Finland
Pulmonary tuberculosis, Tuberculoma pulmonum
+∞
29.2
28
*
0112A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, BAKTERIOL.VARMA]
+∞
28.2
27
*
01106
ICD-8 Finland
Pulmonary tuberculosis, Pulmonum alia sive NUD
+∞
28.2
27
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
28.1
325
1621
1240
FHL
Bronchoscopy
5.4
27.6
85
163
R03DA04
ATC
theophylline; systemic, rectal
2.4
27.6
254
1135
H02AB06
ATC
prednisolone; systemic
1.7
27.0
977
7194
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
16.0
25.4
41
26
01297
ICD-8 Finland
Other respiratory tuberculosis, Suspecta
+∞
24.0
23
*
J01MA14
ATC
moxifloxacin; systemic
2.3
23.5
226
1032
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
23.2
352
1952
01109
ICD-8 Finland
Pulmonary tuberculosis, Unspecified
+∞
22.9
22
*
R03AC02
ATC
salbutamol; inhalant
1.6
22.6
944
7100
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.4
22.6
196
849
R03AC12
ATC
salmeterol; inhalant
2.6
22.5
168
669
R03BB01
ATC
ipratropium bromide; inhalant
2.4
22.1
198
871
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
2.2
21.8
251
1244
A15.8
ICD-10 Finland
Other respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
20.9
20
*
J96.1
ICD-10 Finland
Chronic respiratory failure
3.5
20.7
100
298
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.8
20.1
130
475
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
19.6
146
578
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.8
19.2
131
495
TGC00
NOMESCO Finland
Bronchial lavation
3.7
19.2
85
236
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
8.8
17.9
38
44
J47
ICD-10 Finland
Bronchiectasis
4.0
17.8
72
185
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
26.9
17.8
24
9
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.6
17.8
81
231
A15.4
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, confirmed bacteriologically and histologically
+∞
17.7
17
*
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
95.8
17.6
19
*
R04.2
ICD-10 Finland
Haemoptysis
2.8
17.1
113
419
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.0
16.0
94
325
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
15.3
347
2179
H02AB07
ATC
prednisone; oral
1.7
14.9
322
1994
51120
ICD-8 Finland
Pleurisy, Other specified forms of effusion, except tuberculous
25.2
14.7
20
8
01710
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum colli
+∞
14.6
14
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.1
14.0
75
244
J01FA06
ATC
roxithromycin; oral
1.5
14.0
749
5767
0118X
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, EPÄILTY]
+∞
13.6
13
*
0119A
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, BAKTERIOLOG. VARMA]
+∞
13.6
13
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
13.5
797
6250
J45.8
ICD-10 Finland
Mixed asthma
3.0
12.8
75
259
R03BA01
ATC
beclometasone; inhalant
1.7
12.8
283
1760
M05BA04
ATC
alendronic acid; oral
1.9
12.7
190
1038
0120B
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, HISTOLOGISESTI VARMENNETTU]
+∞
12.5
12
*
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
12.2
141
696
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.4
11.9
102
439
R03BA02
ATC
budesonide; inhalant
1.6
11.9
305
1975
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
65.3
11.6
13
*
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
11.5
11
*
A02BA02
ATC
ranitidine; systemic
1.5
11.3
435
3105
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
11.2
834
6752
L04AX01
ATC
azathioprine; systemic
2.6
11.1
79
310
R03AC13
ATC
formoterol; inhalant
2.2
10.9
114
543
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
10.9
118
570
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
3.7
10.7
45
123
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.2
10.6
110
522
5111B
ICD-9 Finland
Pleurisy, With effusion, with mention of a bacterial cause other than tuberculosis[PLEURITIS EXSUDATIVA ALIA DEFINITA]
60.3
10.6
12
*
03199
ICD-8 Finland
Other diseases due to Mycobacteria, Other and unspecified
+∞
10.4
10
*
0112X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, EPÄILTY]
+∞
10.4
10
*
01103
ICD-8 Finland
Pulmonary tuberculosis, Bronchialis
+∞
10.4
10
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.2
10.4
54
174
R03BB02
ATC
oxitropium bromide; inhalant
3.6
10.3
45
127
J01MA12
ATC
levofloxacin; systemic
1.5
10.0
387
2755
13599
ICD-8 Finland
Sarcoidosis, Unspecified
9.2
10.0
20
22
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.0
9.9
118
592
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
9.9
335
2315
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
5.7
9.8
27
48
01908
ICD-8 Finland
Late effects of tuberculosis, Sequelae aliae o tuberculosis organorum respirationis
20.1
9.8
14
7
Z20.1
ICD-10 Finland
Contact with and exposure to tuberculosis
9.6
9.8
19
20
A98
ICPC
Health maint/preventive medicine
0.7
9.7
1349
14938
R06.0
ICD-10 Finland
Dyspnoea
1.4
9.6
477
3573
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
9.5
189
1140
R05CB01
ATC
acetylcysteine; inhalant, oral
2.7
9.4
61
228
N05CD07
ATC
temazepam; oral
1.5
9.4
325
2260
A18.0
ICD-10 Finland
Tuberculosis of bones and joints
+∞
9.4
9
*
01292
ICD-8 Finland
Other respiratory tuberculosis, Lymphonodorum tracheobronchialium et mediastini
+∞
9.4
9
*
J43.9
ICD-10 Finland
Emphysema, unspecified
2.9
9.3
54
187
48609
ICD-8 Finland
Pneumonia, unspecified
3.7
9.3
39
107
51899
ICD-8 Finland
Bronchiectasis
8.3
9.1
19
23
A31.9
ICD-10 Finland
Mycobacterial infection, unspecified
36.8
9.0
11
*
J01AA02
ATC
doxycycline; systemic
1.3
9.0
1454
13099
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.1
9.0
48
159
XG410
NOMESCO Finland
Flow-volume spirometry
2.2
8.9
88
409
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
8.9
289
1977
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
4.4
8.9
31
72
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
8.8
87
404
A10BA02
ATC
metformin; oral
0.7
8.7
344
4599
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.6
8.4
59
232
A16.8
ICD-10 Finland
Other respiratory tuberculosis, without mention of bacteriological or histological confirmation
+∞
8.3
8
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
8.3
8
*
48601
ICD-8 Finland
More specifically, unspecified pneumonia and the pleural irritation caused by it
5.8
8.3
22
38
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.3
783
6497
132
Kela drug reimbursment
Sarcoidosis
4.9
8.2
25
51
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
8.2
134
759
R95
ICPC
Chron obstructive pulmonary disease
2.3
7.9
68
299
P01BA02
ATC
hydroxychloroquine; oral
1.8
7.8
128
727
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
25.1
7.6
10
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
3.3
7.6
36
111
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
3.9
7.5
29
75
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
4.1
7.5
27
66
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
3.1
7.4
38
124
A07EC01
ATC
sulfasalazine; oral, rectal
1.8
7.4
132
770
0120A
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, BAKTERIOLOGISESTI VARMA]
+∞
7.3
7
*
01202
ICD-8 Finland
NA
+∞
7.3
7
*
A18.8
ICD-10 Finland
Tuberculosis of other specified organs
+∞
7.3
7
*
0110B
ICD-8 Finland
NA
+∞
7.3
7
*
48509
ICD-8 Finland
Bronchopneumonia, unspecified
3.7
7.2
29
79
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
7.1
515
4085
J46
ICD-10 Finland
Status asthmaticus
2.4
7.1
56
234
R03AC03
ATC
terbutaline; inhalant
1.5
7.0
230
1575
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
2.4
7.0
55
230
13597
ICD-8 Finland
Sarcoidosis, Suspecta
5.2
6.9
20
39
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
2.3
6.9
58
252
L04AA13
ATC
leflunomide; oral
2.7
6.9
45
171
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.8
6.8
41
149
N02AC04
ATC
dextropropoxyphene; oral
1.8
6.8
106
595
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.1
6.8
70
334
A06AD11
ATC
lactulose; oral
1.4
6.7
362
2734
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
6.5
147
2184
Y3498
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Other illnesses, accidents or surgeries
10.0
6.5
12
12
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
2.6
6.5
44
173
H02AB04
ATC
methylprednisolone; systemic
1.5
6.5
251
1782
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
6.5
581
4751
A31.89
ICD-10 Finland
Other mycobacterial infections
70.0
6.4
7
*
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
7.4
6.4
14
19
49109
ICD-8 Finland
Chronic bronchitis, Unspecified
4.9
6.3
19
39
A15.5
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, confirmed bacteriologically and histologically
+∞
6.3
6
*
A15
ICD-10 Finland
Respiratory tuberculosis, bacteriologically and histologically confirmed
+∞
6.3
6
*
M49.0*A18.0
ICD-10 Finland
Tuberculosis of spine
+∞
6.3
6
*
A19.1
ICD-10 Finland
Acute miliary tuberculosis of multiple sites
+∞
6.3
6
*
0116A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA,BAKTER.VARMA]
+∞
6.3
6
*
01105
ICD-8 Finland
Pulmonary tuberculosis, Disseminata pulmonum
+∞
6.3
6
*
A16.4
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation
+∞
6.3
6
*
A18.3
ICD-10 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands
+∞
6.3
6
*
0118A
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, BAKTERIOLOG.VARMA]
+∞
6.3
6
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
6.2
51
221
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
3.3
6.2
29
90
5188X
ICD-9 Finland
Other diseases of lung
5.0
6.2
18
36
Y0499
ICD-8 Finland
Investigation of respiratory system
2.9
6.1
35
123
5120A
ICD-9 Finland
Pneumothorax, Spontaneous tension pneumothorax
6.7
6.0
14
21
D86.0
ICD-10 Finland
Sarcoidosis of lung
3.4
6.0
26
76
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
309
668
5.18
136.46
6.3
2.6
—
—
—
0
0
155
217
7.58
105.83
9.9
3.7
—
—
—
0
0
150
401
3.93
49.44
2.6
1.5
—
—
—
0
0
124
424
3.03
27.75
1.8
1.6
1.7
13.2
iu/ml
0.42
44
92
85
235
3.72
26.67
1.2
1.1
—
—
—
0
0
94
290
3.34
24.97
1.5
1.4
—
—
—
0
0
31
36
8.71
24.55
1.8
1.4
—
—
—
0
0
38
57
6.76
24.24
1.4
1.4
—
—
—
0
0
58
132
4.48
23.66
1.6
1.6
—
—
—
0
0
49
97
5.14
23.57
7.1
3.5
—
—
—
0
0
79
232
3.49
22.68
1.6
1.4
—
—
—
0
0
73
228
3.27
19.06
1.4
1.4
—
—
—
0
0
78
261
3.06
18.17
1.4
1.4
—
—
—
0
0
106
423
2.58
17.76
1.6
1.6
—
—
—
0
0
100
398
2.58
16.86
1.7
1.6
—
—
—
0
0
15
13
11.61
14.43
1.1
1.4
—
—
—
0
0
73
299
2.49
11.68
1.7
1.7
—
—
—
0
0
1352
15167
0.74
11.01
5.2
5.2
2.6
2.6
mmol/l
0.09
1217
13606
50
175
2.90
10.88
1.3
1.3
28.6
15.2
u/l
2.26
44
163
25
55
4.58
10.71
1.3
2.6
2191.3
36891.6
u/ml
—
7
13
116
607
1.96
10.19
1.8
1.9
39.8
38.5
u/l
0.31
103
524
435
3222
1.43
9.65
2.1
1.9
—
—
—
0
0
1321
14737
0.76
9.37
4.6
4.6
4.5
4.4
mmol/l
0.45
1191
13320
1544
16838
0.75
9.12
35.0
25.1
249.5
240.2
e9/l
5.40
1495
16244
1546
16850
0.75
9.04
35.0
25.1
7.3
6.9
e9/l
3.85
1493
16184
1546
16847
0.75
9.00
35.1
25.2
130.9
132.7
g/l
4.39
1513
16436
314
2213
1.48
9.00
7.2
6.8
5.1
5.1
kpa
0.39
299
2090
314
2213
1.48
9.00
7.2
6.8
11.4
11.6
kpa
0.24
300
2091
1546
16844
0.75
8.96
34.9
25.1
4.4
4.4
e12/l
1.85
1490
16178
179
1111
1.66
8.94
2.9
2.7
10.3
10.8
g/l
0.73
168
1009
314
2218
1.48
8.89
7.4
6.8
1.4
1.2
mmol/l
0.44
260
1695
316
2239
1.48
8.81
2.1
1.8
—
—
—
0
0
1310
14565
0.77
8.62
4.6
4.6
1.4
1.4
mmol/l
0.97
1174
13028
313
2242
1.46
8.23
2.0
1.8
—
—
—
0
0
28
85
3.32
7.79
1.5
2.1
754.4
563.0
e6/l
0.41
23
72
42
163
2.61
7.61
1.7
1.7
—
—
—
0
0
1364
14992
0.78
7.58
4.9
4.9
6.0
6.1
mmol/l
0.76
1216
13278
1273
14098
0.78
7.46
4.1
4.1
1.3
1.3
mmol/l
0.01
1129
12502
41
159
2.61
7.45
1.4
1.6
—
—
—
0
0
41
159
2.61
7.45
1.4
1.6
—
—
—
0
0
41
159
2.61
7.45
1.4
1.6
—
—
—
0
0
55
245
2.28
7.42
1.8
1.6
—
—
—
0
0
43
173
2.51
7.26
1.7
1.7
—
—
—
0
0
121
717
1.73
7.21
1.5
1.2
215.5
231.3
u/ml
0.08
108
652
51
223
2.32
7.19
1.3
1.3
473.5
335.6
u/l
0.88
46
212
46
194
2.40
7.04
1.9
1.6
—
—
—
0
0
1502
16257
0.78
6.96
27.9
20.3
85.7
85.2
umol/l
0.16
1502
16249
311
4115
0.72
6.76
2.9
3.2
0.9
0.8
ug/l
0.16
209
2887
28
94
3.00
6.65
1.6
2.1
641.1
674.6
e6/l
0.07
14
38
11
18
6.14
6.43
2.3
1.7
—
—
—
0
0
50
229
2.21
6.36
1.4
1.5
5.8
6.5
mmol/l
0.82
45
215
472
5805
0.77
6.16
4.0
4.6
21.8
22.0
%
0.07
237
3001
1518
16322
0.80
6.05
28.0
20.6
4.0
4.0
mmol/l
0.09
1480
15767
12
23
5.24
6.01
1.2
1.2
—
—
—
0
0
91
526
1.76
5.97
1.6
1.7
—
—
—
0
0
1516
16292
0.80
5.94
27.8
20.4
139.4
139.6
mmol/l
2.73
1481
15765
361
2804
1.34
5.82
4.2
3.0
0.8
0.8
mmol/l
0.59
332
2585
613
7235
0.79
5.62
4.5
5.3
4.2
4.4
ug/l
0.05
530
6343
71
388
1.86
5.62
1.6
2.0
10.9
13.4
mg/l
0.91
62
354
25
88
2.86
5.51
1.6
1.3
1.5
0.7
u/ml
0.32
19
51
1320
14351
0.81
5.51
6.2
6.4
40.5
40.9
mmol/mol
0.76
1194
12980
1517
16231
0.81
5.27
14.9
10.9
25.4
25.3
u/l
0.01
1456
15473
21
69
3.06
5.22
1.6
1.9
—
—
—
0
0
21
69
3.06
5.22
1.6
1.9
—
—
—
0
0
26
97
2.70
5.17
1.5
1.7
—
—
—
0
0
26
97
2.70
5.17
1.5
1.7
—
—
—
0
0
26
97
2.70
5.17
1.5
1.7
—
—
—
0
0
241
1792
1.38
5.12
8.5
7.6
119.9
119.9
g/l
0.01
232
1725
1328
14379
0.82
5.08
22.4
16.3
74.6
73.3
ml/min/173m2
1.23
1121
11873
21
71
2.98
4.98
1.6
1.8
—
—
—
0
0
21
73
2.89
4.76
1.6
1.7
—
—
—
0
0
25
96
2.62
4.73
1.7
1.5
—
—
—
0
0
987
8820
1.21
4.68
8.3
6.0
10.6
12.4
umol/l
6.98
941
8309
14
38
3.70
4.64
1.8
2.3
—
—
—
0
0
25
97
2.59
4.64
1.7
1.5
—
—
—
0
0
25
97
2.59
4.64
1.5
1.7
—
—
—
0
0
15
43
3.50
4.61
1.2
1.2
—
—
—
0
0
173
1244
1.42
4.49
8.4
7.0
24.9
24.5
mmol/l
0.73
163
1165
55
302
1.84
4.36
1.4
1.4
1859.5
1760.3
e6/l
0.11
37
219
19
66
2.89
4.33
1.1
1.2
—
—
—
0
0
1013
9119
1.20
4.33
12.4
8.5
4.4
4.3
e9/l
0.44
902
7886
335
2694
1.28
4.17
2.8
2.4
2.2
2.3
g/l
1.34
309
2456
142
1002
1.44
4.10
9.2
8.3
24.3
24.3
mmol/l
0.01
133
912
32
148
2.18
4.09
1.3
1.1
—
—
u/ml
—
0
0
71
431
1.67
4.01
2.0
2.3
119.6
127.1
g/l
1.72
48
320
306
2447
1.29
3.98
6.1
5.2
1.1
1.0
mmol/l
2.19
277
2227
27
118
2.30
3.94
1.7
1.4
—
—
—
0
0
1250
13463
0.84
3.91
26.1
18.5
38.3
38.6
%
0.33
753
8415
278
2211
1.29
3.77
4.0
3.9
238.8
248.9
u/l
0.60
261
2066
124
868
1.45
3.76
2.0
1.9
2.0
2.3
ug/l
0.11
107
746
565
4869
1.21
3.75
3.8
3.1
35.5
35.4
u/l
0.02
531
4602
74
463
1.62
3.74
1.6
1.4
—
—
—
0
0
74
463
1.62
3.74
1.6
1.4
—
—
—
0
0
53
303
1.77
3.73
5.0
5.2
499.1
813.6
iu/ml
—
8
42
314
2547
1.27
3.64
2.9
2.5
21.3
21.9
%
0.32
263
2137
1302
13910
0.85
3.45
4.9
4.6
1.9
2.1
mu/l
1.56
1160
12358
48
275
1.76
3.39
1.4
1.4
30283.0
71047.0
e6/l
0.83
28
166
352
2920
1.24
3.37
2.8
2.5
11.4
12.1
umol/l
0.97
332
2663
176
1335
1.34
3.36
1.9
1.6
—
—
—
0
0
30
147
2.05
3.36
1.6
1.6
—
—
—
0
0
21
89
2.37
3.32
1.6
1.9
16.6
15.3
%
0.12
12
38
21
89
2.37
3.32
1.7
1.8
—
—
—
0
0
216
1692
1.31
3.30
6.7
6.3
11.7
11.3
mmol/l
0.35
205
1590
24
109
2.21
3.25
1.3
1.3
—
—
—
0
0
43
242
1.79
3.23
8.3
6.4
13.8
12.3
mg/l
1.22
37
224
243
1948
1.28
3.12
3.2
3.8
58.5
20.9
ug/l
0.54
204
1632
52
321
1.63
2.85
3.3
3.7
1.0
1.7
%
1.06
40
242
1480
15536
0.87
2.67
26.2
17.4
27.8
27.6
mg/l
0.07
1284
12712
153
1181
1.32
2.65
4.0
3.7
2.0
1.9
mmol/l
0.02
114
864
63
418
1.52
2.58
2.2
1.8
—
—
—
0
0
384
3301
1.20
2.58
2.0
1.6
1.3
1.4
mg/l
0.27
299
2558
481
5445
0.85
2.50
3.7
3.9
14.1
9.1
mg/mmol
0.85
301
3473
413
3584
1.19
2.49
4.9
4.1
452.6
310.5
ng/l
0.49
349
3058
16
69
2.33
2.48
1.4
1.6
—
—
—
0
0
1157
12306
0.88
2.43
29.3
20.8
14.1
13.9
%
5.05
1138
11950
225
1847
1.24
2.40
4.6
3.4
5.8
5.8
kpa
0.15
218
1776
38
227
1.69
2.40
1.2
1.3
118.0
130.3
u/ml
—
9
44
201
1636
1.25
2.32
8.3
6.1
1.4
1.4
mmol/l
0.34
192
1554
76
537
1.43
2.31
3.1
3.4
24.8
25.1
mmol/l
0.20
70
465
204
1666
1.25
2.29
2.2
2.6
66.1
66.0
g/l
0.13
178
1497
83
597
1.40
2.29
1.5
1.2
—
—
—
0
0
154
1217
1.28
2.27
1.8
1.7
—
—
—
0
0
157
1249
1.28
2.21
4.2
3.7
5.1
5.2
kpa
0.42
148
1139
16
73
2.20
2.21
3.0
2.5
1313.7
1420.8
u/ml
0.07
16
73
84
1141
0.73
2.21
1.9
2.1
11.8
12.0
nmol/l
0.05
71
973
57
385
1.49
2.19
2.0
1.5
0.2
0.2
g/l
0.22
57
366
222
1842
1.23
2.17
4.7
3.4
2.0
2.0
mmol/l
0.03
172
1435
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
97
730
1.34
2.06
2.3
2.6
0.3
0.3
u/ml
0.71
52
423
66
466
1.43
2.05
1.2
1.2
1.2
0.9
u/ml
0.17
12
36
7
21
3.34
1.96
1.0
1.3
—
—
—
0
0
5
11
4.55
1.94
1.0
1.1
—
—
—
0
0
5
11
4.55
1.94
1.2
1.2
—
—
—
0
0
48
322
1.50
1.94
1.6
1.3
—
—
—
0
0
52
747
0.69
1.93
1.5
1.8
—
—
—
0
0
196
1628
1.22
1.92
2.2
2.1
0.2
0.2
g/l
0.00
184
1500
470
5233
0.87
1.91
3.3
3.1
7.0
7.3
mmol/l
0.71
388
4292
532
4800
1.14
1.91
2.5
2.2
3.0
3.1
mg/l
0.31
450
4014
275
2361
1.19
1.90
9.0
6.3
103.9
104.3
mmol/l
0.77
270
2288
51
349
1.47
1.88
1.5
1.6
—
—
—
0
0
14
65
2.16
1.88
1.4
1.4
—
—
—
0
0
14
65
2.16
1.88
1.4
1.4
—
—
—
0
0
14
65
2.16
1.88
1.4
1.4
—
—
—
0
0
14
65
2.16
1.88
1.4
1.4
—
—
—
0
0
8
28
2.86
1.86
1.1
1.0
—
—
—
0
0
211
1775
1.21
1.83
2.7
2.5
5.0
6.6
ug/l
1.58
172
1506
80
597
1.35
1.82
5.7
3.9
3.8
3.9
mmol/l
0.94
75
546
7
23
3.05
1.80
1.0
1.2
—
—
—
0
0
20
109
1.84
1.77
1.3
1.1
250.0
143.2
titre
—
6
19
19
102
1.87
1.76
1.1
1.3
—
—
—
0
0
19
102
1.87
1.76
1.2
1.3
—
—
—
0
0
19
102
1.87
1.76
1.1
1.3
—
—
—
0
0
14
67
2.10
1.76
1.0
1.0
—
—
—
0
0
45
305
1.48
1.75
1.1
1.1
—
—
—
0
0
30
185
1.63
1.75
1.3
1.4
—
—
—
0
0
61
439
1.40
1.74
1.2
1.2
—
—
—
0
0
32
201
1.60
1.74
4.0
3.5
50.1
57.4
%
0.74
21
127
26
155
1.69
1.72
1.2
1.3
—
—
—
0
0
7
24
2.92
1.72
1.0
1.2
—
—
—
0
0
5
13
3.85
1.71
1.0
1.2
—
—
—
0
0
575
5250
1.13
1.71
2.8
2.5
58.4
58.0
u/l
0.09
533
4805
111
878
1.28
1.70
6.2
3.4
24.3
24.1
mmol/l
0.44
98
776
214
1818
1.20
1.69
3.9
3.1
226.5
272.8
ng/l
1.05
196
1672
6
19
3.16
1.66
1.0
1.2
—
—
—
0
0
7
25
2.81
1.65
1.1
1.1
—
—
—
0
0
60
436
1.39
1.64
1.2
1.2
—
—
—
0
0
937
8808
1.11
1.63
8.1
6.7
1.2
1.2
mmol/l
0.11
791
7316
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
339
3009
1.15
1.56
3.3
2.9
1.4
1.3
e6/l
0.22
214
1775
13
64
2.04
1.54
1.2
1.3
2.0
55.8
ug/l
—
6
30
5
15
3.34
1.52
1.0
1.1
—
—
—
0
0
6
21
2.86
1.50
10.2
13.0
5.4
5.8
mmol/l
—
6
21
11
51
2.16
1.50
2.7
2.1
17.5
177.7
ug/l
0.48
11
43
36
242
1.50
1.50
1.7
1.9
—
—
—
0
0
36
242
1.50
1.50
8.1
8.8
7.4
7.6
mmol/l
0.09
30
202
14
72
1.95
1.48
9.1
5.9
50.6
68.3
u/ml
—
5
18
30
194
1.55
1.48
3.4
2.5
—
—
—
0
0
20
117
1.72
1.45
1.1
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.1
—
—
—
0
0
68
520
1.32
1.38
1.5
1.5
—
—
—
0
0
32
215
1.50
1.35
1.3
1.3
85.3
202.9
miu/ml
1.90
13
81
42
298
1.42
1.35
1.4
1.3
—
—
—
0
0
851
8024
1.10
1.34
7.4
5.9
1.2
1.2
mmol/l
0.28
754
7152
178
1523
1.18
1.34
3.8
2.8
4.3
4.5
kpa
0.48
170
1457
102
826
1.25
1.34
2.2
2.0
—
—
—
0
0
23
144
1.60
1.32
1.4
1.3
—
—
—
0
0
19
113
1.69
1.31
2.0
3.7
—
—
—
0
0
815
7679
1.09
1.30
5.4
4.7
33.9
34.5
g/l
2.06
733
7044
9
44
2.05
1.26
1.0
1.1
—
—
—
0
0
644
6013
1.10
1.24
3.7
3.2
2179.6
1956.1
ng/l
0.51
567
5154
10
49
2.05
1.22
1.0
1.1
—
—
—
0
0
33
230
1.44
1.19
1.6
1.3
23.9
26.4
iu/l
0.20
27
191
6
26
2.31
1.18
1.7
1.3
74.7
51.3
umol/l
—
6
26
46
341
1.36
1.18
1.3
1.4
—
—
—
0
0
75
596
1.27
1.18
1.4
1.2
—
—
—
0
0
1081
11277
0.92
1.17
4.0
3.8
15.1
15.1
pmol/l
0.37
956
9955
10
50
2.00
1.16
1.0
1.1
—
—
—
0
0
749
7062
1.09
1.16
4.6
4.3
40.1
59.7
ng/l
1.75
562
5409
11
58
1.90
1.12
1.1
1.2
—
—
—
0
0
8
40
2.00
1.12
1.0
1.1
—
—
—
0
0
7
31
2.26
1.10
1.1
1.3
—
—
—
0
0
240
2137
1.14
1.10
1.3
1.2
16.5
14.2
u/ml
0.19
87
768
12
66
1.82
1.09
1.7
1.2
—
—
—
0
0
14
81
1.73
1.09
1.1
1.1
—
—
—
0
0
176
1536
1.16
1.08
2.7
2.3
31.9
36.4
u/l
0.96
146
1299
706
7471
0.92
1.07
2.3
2.1
90.4
92.3
pmol/l
0.46
382
3940
190
1674
1.15
1.03
1.4
1.4
—
—
—
0
0
80
653
1.23
1.03
1.8
1.8
—
—
—
0
0
1215
11723
1.08
1.02
6.2
4.1
16.9
14.5
mm/h
4.43
1121
10675
9
47
1.92
1.02
1.0
1.1
—
—
—
0
0
115
977
1.19
0.99
1.5
1.7
1.5
1.6
g/l
0.63
100
828
1306
12651
1.07
0.97
10.6
7.5
79.0
81.3
u/l
0.92
1222
11771
241
2168
1.12
0.96
9.6
8.6
—
—
—
0
0
567
5324
1.09
0.96
2.4
2.2
233.2
244.0
u/l
0.11
525
4950
421
3902
1.10
0.96
3.3
2.7
5.7
4.7
e6/l
0.88
376
3446
9
51
1.77
0.94
37.6
17.7
1515.7
1528.0
nmol/l
—
9
51
247
2229
1.12
0.94
1.4
1.2
68.4
38.8
iu/ml
0.74
75
719
30
217
1.39
0.93
1.6
1.4
—
—
—
0
0
264
2393
1.12
0.93
2.5
2.4
1.8
1.8
%
0.14
227
2085
135
1171
1.16
0.92
1.6
1.5
—
—
—
0
0
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
13
78
1.67
0.91
1.7
1.4
—
—
—
0
0
358
3875
0.91
0.91
1.6
1.6
1.3
1.3
mmol/l
0.07
311
3179
27
193
1.40
0.90
1.6
1.9
—
—
—
0
0
90
757
1.20
0.89
2.0
1.9
—
—
—
0
0
48
377
1.28
0.88
1.8
2.7
31.3
34.8
umol/l
0.32
38
310
15
95
1.58
0.87
1.5
1.1
—
—
—
0
0
15
95
1.58
0.87
1.5
1.1
—
—
—
0
0
41
316
1.30
0.87
1.6
1.4
25.8
640.7
e6/l
1.11
33
261
41
316
1.30
0.87
1.6
1.3
32.2
37.3
e6/l
0.08
31
249
15
96
1.57
0.84
1.5
1.1
—
—
—
0
0
15
96
1.57
0.84
1.5
1.1
—
—
—
0
0
15
96
1.57
0.84
1.5
1.1
—
—
—
0
0
8
45
1.78
0.84
1.0
1.1
—
—
—
0
0
71
588
1.21
0.84
1.8
1.7
—
—
—
0
0
19
129
1.48
0.83
1.0
1.1
—
—
—
0
0
87
736
1.19
0.82
4.7
4.0
24.8
24.9
mmol/l
0.10
79
665
81
681
1.20
0.82
2.5
2.2
286.8
495.3
ug/l
1.30
75
636
94
802
1.18
0.81
4.6
5.5
1.7
1.6
%
0.35
89
754
18
122
1.48
0.80
1.5
1.5
—
—
—
0
0
13
82
1.59
0.78
1.2
1.0
—
—
—
0
0
725
7579
0.94
0.77
5.1
4.3
—
—
—
0
0
24
174
1.38
0.76
1.5
1.2
3.3
3.5
u/ml
0.03
12
57
29
381
0.76
0.75
2.6
1.8
12.3
3.1
mg/l
0.57
21
293
5
24
2.09
0.74
1.6
1.5
82.9
141.4
ng/l
—
5
24
33
256
1.29
0.70
1.1
1.1
—
—
—
0
0
20
143
1.40
0.70
1.4
1.5
29.8
30.4
u/ml
—
5
28
29
221
1.32
0.69
1.2
1.2
310.2
277.7
u/ml
0.17
21
122
9
58
1.55
0.69
1.0
1.2
—
—
—
0
0
14
93
1.51
0.69
3.9
2.1
—
—
—
0
0
12
78
1.54
0.65
1.0
1.1
—
—
—
0
0
7
44
1.59
0.65
1.3
1.2
—
—
—
0
0
1075
11058
0.95
0.64
6.1
5.0
6114.9
2006.5
e6/l
0.46
27
211
189
2066
0.91
0.63
4.5
4.7
32.1
33.1
%
0.55
112
1326
31
243
1.28
0.62
2.1
2.3
26.6
24.7
mg/l
—
9
59
150
1354
1.12
0.62
1.9
1.7
1.7
1.6
%
1.15
129
1126
15
104
1.45
0.62
1.1
1.3
15.1
11.1
mmol/l
—
6
30
11
71
1.55
0.62
1.7
1.5
—
—
—
0
0
10
63
1.59
0.61
1.1
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
2.3
—
0.6
—
0
14
204
1877
1.10
0.59
2.6
2.6
6.1
10.2
umol/l
5.60
173
1650
670
6438
1.06
0.59
2.4
2.2
79.9
78.5
nmol/l
0.55
582
5577
14
97
1.45
0.59
1.4
2.1
—
—
—
0
0
22
166
1.33
0.58
1.5
1.2
2.3
5.1
u/ml
1.03
11
72
142
1285
1.11
0.58
3.7
2.9
56.8
61.1
ml/min/173m2
0.85
70
552
30
238
1.26
0.56
1.3
1.2
—
—
—
0
0
777
7506
1.05
0.56
2.7
2.5
—
—
—
0
0
147
1337
1.11
0.55
2.1
2.1
363.9
374.7
nmol/l
0.31
130
1197
306
2875
1.07
0.55
3.6
3.1
2.2
1.9
e6/l
0.37
179
1648
29
231
1.26
0.54
1.4
2.2
41.3
195.7
u/ml
0.42
29
223
151
1385
1.10
0.49
3.7
3.6
89.9
96.5
ng/l
0.48
129
1167
273
2899
0.93
0.49
27.8
28.8
1.5
1.5
inr
0.15
39
389
17
128
1.33
0.47
1.2
1.1
0.5
1.2
u/ml
—
5
46
54
466
1.16
0.47
1.5
1.5
262.7
272.7
ug/g
0.13
35
280
26
209
1.25
0.46
1.1
1.1
192.5
75.9
iu/ml
—
6
35
103
931
1.11
0.46
4.1
2.4
1.3
1.2
%
1.10
103
925
466
4473
1.05
0.44
3.3
2.9
2691.3
7296.7
umol/l
1.87
389
3785
39
459
0.85
0.44
2.0
2.3
109.8
102.3
ug/min
0.04
22
273
25
202
1.24
0.43
1.3
1.4
—
—
—
0
0
25
202
1.24
0.43
1.3
1.4
—
—
—
0
0
370
3532
1.06
0.43
5.3
4.4
1.0
1.0
kg/l
0.11
62
560
21
166
1.27
0.43
1.1
1.1
—
—
—
0
0
47
405
1.16
0.43
2.8
2.6
14.7
15.8
%
1.02
29
208
6
92
0.65
0.42
2.8
1.1
—
—
—
0
0
6
92
0.65
0.42
2.8
1.1
—
—
—
0
0
25
203
1.23
0.42
1.3
1.4
—
—
—
0
0
609
5895
1.04
0.41
3.4
3.3
2.3
2.3
mmol/l
0.62
518
5005
155
1440
1.08
0.41
2.3
2.2
210.8
154.0
ug/g
0.67
121
1119
25
204
1.23
0.40
1.3
1.4
—
—
—
0
0
25
204
1.23
0.40
1.3
1.4
—
—
—
0
0
72
645
1.12
0.39
3.2
3.4
2.0
1.8
ratio
—
7
47
180
1921
0.93
0.39
4.6
3.8
—
—
—
0
0
44
382
1.15
0.38
3.1
3.3
2276.9
1044.4
u/ml
0.32
39
354
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
38
327
1.16
0.37
1.1
1.2
40.7
41.9
u/l
0.03
31
283
13
99
1.31
0.35
1.8
1.5
6.3
8.2
u/l
—
8
49
15
118
1.27
0.33
1.0
1.0
—
—
—
0
0
669
6521
1.04
0.33
3.4
2.8
154.9
153.8
ug/l
0.03
601
5861
15
119
1.26
0.31
1.0
1.0
—
—
—
0
0
30
348
0.86
0.31
2.0
1.7
—
—
—
0
0
75
685
1.10
0.31
2.6
3.1
5615.3
6204.7
u/ml
0.03
65
586
40
453
0.88
0.31
4.1
3.5
7.8
7.8
mmol/l
0.02
40
444
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
84
1.31
0.30
1.0
1.1
—
—
—
0
0
24
203
1.18
0.30
1.3
1.4
—
—
—
0
0
98
910
1.08
0.29
4.1
2.4
0.7
0.7
%
0.48
93
875
588
6027
0.97
0.28
5.0
4.3
—
—
—
0
0
85
786
1.08
0.28
2.1
2.5
—
—
—
0
0
72
661
1.09
0.28
3.2
3.4
45.1
63.5
mg/l
1.02
57
543
10
76
1.32
0.28
1.0
1.1
—
—
—
0
0
85
787
1.08
0.27
2.1
2.5
7.6
7.4
g/l
0.46
53
571
72
662
1.09
0.27
3.2
3.4
84.6
83.1
mg/l
0.01
57
546
25
290
0.86
0.27
1.6
1.3
—
—
—
0
0
10
77
1.30
0.26
1.1
1.2
—
—
—
0
0
13
105
1.24
0.24
1.1
1.1
—
—
—
0
0
20
234
0.85
0.24
1.4
1.8
200.3
213.0
pmol/l
0.32
20
218
84
785
1.07
0.23
2.1
2.5
3.7
3.9
g/l
0.41
52
551
431
4422
0.97
0.23
1.7
1.6
19.7
19.9
nmol/l
0.11
364
3730
12
146
0.82
0.22
1.8
2.2
396.5
631.4
ml
—
6
89
14
167
0.84
0.21
1.5
1.3
668898.8
85320.7
e6/l
—
8
118
5
42
1.19
0.21
1.8
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
14
0.00
0.20
0.0
1.3
—
4221.3
—
0
8
0
14
0.00
0.20
0.0
1.0
—
27.2
—
0
14
6
48
1.25
0.20
1.0
1.3
—
—
—
0
0
6
52
1.15
0.19
1.8
3.0
—
—
—
0
0
7
58
1.21
0.18
1.1
1.3
—
—
—
0
0
18
157
1.15
0.17
1.6
1.2
23.6
79.9
u/ml
—
5
6
18
157
1.15
0.17
1.1
1.2
42.5
47.9
u/l
0.42
13
105
50
537
0.93
0.17
2.1
2.5
0.0
0.0
g/l
0.00
41
484
46
427
1.08
0.16
3.8
3.9
34.0
29.0
mg/l
0.30
28
287
8
72
1.11
0.16
1.4
1.1
—
—
—
0
0
21
187
1.12
0.15
1.0
1.0
—
—
—
0
0
56
526
1.07
0.15
3.1
3.1
0.8
0.8
nmol/l
0.65
48
414
78
741
1.05
0.15
2.2
2.5
10.0
10.4
g/l
0.30
60
618
27
246
1.10
0.14
1.6
1.3
12.8
9.3
u/l
0.58
20
193
13
149
0.87
0.13
1.0
1.2
10.1
7.5
mmol/l
—
8
103
54
571
0.94
0.13
2.1
2.4
0.0
0.0
g/l
1.70
45
515
50
529
0.94
0.12
2.1
2.5
0.0
0.0
g/l
0.00
41
482
40
377
1.06
0.11
2.1
1.6
—
—
—
0
0
415
4093
1.02
0.10
3.2
2.4
—
—
—
0
0
33
310
1.07
0.10
2.7
2.0
1.6
1.7
mmol/l
0.39
33
302
12
106
1.13
0.09
2.4
2.4
—
—
—
0
0
63
656
0.96
0.09
2.1
2.6
0.7
1.4
g/l
1.06
47
552
5
46
1.09
0.09
1.0
1.4
—
—
—
0
0
75
723
1.04
0.09
2.0
2.6
3.0
3.1
g/l
0.67
53
562
1013
10065
1.01
0.09
6.3
4.9
6.8
6.9
mmol/l
0.54
961
9467
500
4946
1.01
0.09
4.1
3.3
0.5
0.5
e6/l
0.07
404
3846
19
206
0.92
0.08
1.5
1.6
70.5
65.0
%
0.29
14
136
918
9239
0.99
0.08
4.3
3.1
54.7
55.3
u/l
0.05
853
8397
7
81
0.86
0.07
1.1
1.4
—
—
—
0
0
7
81
0.86
0.07
1.1
1.4
—
—
—
0
0
7
82
0.85
0.07
2.1
1.6
11.4
16.6
nmol/l
—
7
73
782
7869
0.99
0.07
4.7
4.0
0.0
0.0
estimate
0.50
140
1426
9
86
1.05
0.07
3.3
3.3
241.3
214.8
u/l
—
9
86
144
1413
1.02
0.07
1.4
1.4
—
—
—
0
0
41
393
1.04
0.07
1.1
1.2
—
—
—
0
0
43
413
1.04
0.06
1.6
1.7
8062.9
17915.2
e6/l
1.65
27
305
399
4027
0.99
0.06
1.9
1.8
1141.1
1165.5
nmol/l
0.23
299
2979
23
217
1.06
0.06
1.6
1.5
—
—
—
0
0
10
110
0.91
0.05
1.5
1.3
—
—
—
0
0
780
7765
1.01
0.05
4.6
4.0
0.0
0.0
estimate
0.00
137
1467
34
353
0.96
0.04
1.5
1.2
3.9
4.2
u/ml
—
6
52
48
466
1.03
0.04
1.4
1.4
—
—
—
0
0
403
4006
1.01
0.03
1.7
1.7
16667116.5
12802656.3
pmol/l
0.08
312
3226
58
567
1.02
0.03
1.1
1.0
—
—
—
0
0
281
2789
1.01
0.03
1.3
1.2
2.0
1.5
u/ml
0.26
77
695
18
188
0.96
0.02
2.3
2.0
4.0
2.4
u/field
—
9
65
60
608
0.99
0.01
2.0
2.3
37.8
37.0
g/l
0.52
44
513
431
4317
1.00
0.00
5.2
4.3
0.0
0.0
estimate
0.50
127
1386
777
7764
1.00
0.00
6.1
5.4
0.0
0.0
estimate
0.00
137
1466
11
111
0.99
0.00
1.5
1.3
—
—
—
0
0
12
121
0.99
0.00
1.4
1.1
—
52.9
—
0
14
27
269
1.00
0.00
1.2
1.2
—
—
—
0
0
147
1471
1.00
0.00
4.2
3.7
1.2
1.2
mmol/l
0.25
129
1263
30
304
0.99
0.00
1.5
1.7
2.7
5.0
iu/l
—
9
98
17
168
1.01
0.00
1.3
1.1
—
—
—
0
0
25
248
1.01
0.00
1.5
1.2
41.0
43.6
u/ml
—
6
18
347
3474
1.00
0.00
3.5
3.1
2.5
2.5
mmol/l
0.16
298
3005
74
743
1.00
0.00
1.2
1.2
116.1
131.9
iu/ml
0.13
25
265
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.0
1.1
—
—
—
0
0
12
120
1.00
0.00
1.4
1.1
—
37.5
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.2
1.2
83.9
234.2
iu/ml
—
6
63
0
7
0.00
0.00
0.0
1.1
—
7.6
—
0
7
6
66
0.91
0.00
13.0
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
2.6
—
0
8
6
66
0.91
0.00
13.2
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint TBC_RESP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| TBC_RESP | 2.077 [1.85, 2.33] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.314 |
During the follow-up period (1.1.1998 — 31.12.2019), 1483 out of 2958 females with TBC_RESP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| TBC_RESP | 2.815 [2.49, 3.19] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 2702 out of 4601 males with TBC_RESP died.
Mortality risk
Mortality risk for people of age
years, who have TBC_RESP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.237% | 0.513% |
| 5 | 1.239% | 3.228% |
| 10 | 3.108% | 7.591% |
| 15 | 5.846% | 14.501% |
| 20 | 10.563% | 23.591% |
Relationships between endpoints
↥Index endpoint: TBC_RESP – Respiratory tuberculosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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