No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
740 |
4. Check minimum number of eventsNone |
740 |
5. Include endpointsNone |
740 |
6. Filter based on genotype QC (FinnGen only) |
699 |
Control definitions (FinnGen only)
- Control exclude
- AB1_TUBERCULOSIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Respiratory tuberculosis, confirmed
based on the number of shared cases.
Similar with more cases:
- Respiratory tuberculosis, bacteriologically and histologically confirmed
- Respiratory tuberculosis, confirmed and not-confirmed
- Respiratory tuberculosis
- Tuberculosis
- Tuberculosis, IBD comorbidity
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10043 | 3678 | 6041 |
| Only index persons | 5568 | 2240 | 3328 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.11 | 0.17 |
| Only index persons | 0.11 | 0.08 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 65.07 | 68.60 | 63.07 |
| Only index persons | 58.70 | 59.64 | 58.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 699 | 226 | 473 |
| Unadjusted period prevalence (%) | 0.17 | 0.08 | 0.22 |
| Median age at first event (years) | 63.14 | 56.46 | 66.33 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 740
- Matched controls
- 7400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
307.7
304
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
237.7
215
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
88.3
162.7
86
11
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
7.4
140.3
263
510
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.7
128.0
221
390
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
+∞
78.6
74
*
A70
ICPC
Tuberculosis
733.4
69.2
67
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
67.8
64
*
A15.6
ICD-10 Finland
Tuberculous pleurisy, confirmed bacteriologically and histologically
+∞
54.9
52
*
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
521.4
50.0
49
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
45.4
358
1784
A15.3
ICD-10 Finland
Tuberculosis of lung, confirmed by unspecified means
+∞
43.1
41
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.3
42.3
202
752
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
64.0
41.8
48
8
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
385.9
37.4
37
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.6
36.4
73
142
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
5.2
35.9
78
163
A15.7
ICD-10 Finland
Primary respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
33.6
32
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.4
32.9
90
227
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.2
32.6
156
574
R03BB04
ATC
tiotropium bromide; inhalant
3.1
32.2
162
613
0112A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, BAKTERIOL.VARMA]
+∞
29.4
28
*
TGC00
NOMESCO Finland
Bronchial lavation
6.2
29.1
51
87
J01MA14
ATC
moxifloxacin; systemic
3.4
27.9
112
368
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.6
26.6
95
289
R04.2
ICD-10 Finland
Haemoptysis
4.7
26.0
63
144
1240
FHL
Bronchoscopy
6.7
25.4
41
64
A15.8
ICD-10 Finland
Other respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
24.1
23
*
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
+∞
23.0
22
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.3
22.9
47
93
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
7.3
22.2
33
47
H02AB06
ATC
prednisolone; systemic
2.1
21.4
385
2523
GD1AD
NOMESCO Finland
Thorax CT examination
3.9
21.4
67
186
J47
ICD-10 Finland
Bronchiectasis
6.1
21.1
37
63
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.3
19.8
191
976
J96.1
ICD-10 Finland
Chronic respiratory failure
4.6
19.2
47
108
A15.4
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, confirmed bacteriologically and histologically
+∞
18.8
18
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
18.3
371
2491
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.6
17.8
60
175
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
17.8
165
826
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.6
17.4
59
173
R03DA04
ATC
theophylline; systemic, rectal
2.7
16.8
95
377
R03AC12
ATC
salmeterol; inhalant
3.1
16.1
69
234
0119A
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, BAKTERIOLOG. VARMA]
+∞
15.7
15
*
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
13.6
14.8
25
19
H02AB07
ATC
prednisone; oral
2.2
14.5
136
679
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.8
14.4
79
308
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
14.3
73
274
R05
ICD-10 Finland
Cough
2.1
14.1
147
766
XG410
NOMESCO Finland
Flow-volume spirometry
3.5
13.8
49
148
R03AC02
ATC
salbutamol; inhalant
1.8
13.7
374
2678
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
+∞
13.6
13
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
3.4
13.5
49
150
R03BB01
ATC
ipratropium bromide; inhalant
2.7
12.7
74
297
A16.1
ICD-10 Finland
Tuberculosis of lung, bacteriological and histological examination not done
+∞
12.5
12
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
5.4
12.1
24
46
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
12.0
219
1378
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.4
11.8
89
403
SPAT1254
SPAT
Administration of medicine
2.1
11.8
130
689
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
11.7
99
472
J01MA12
ATC
levofloxacin; systemic
1.9
11.7
168
977
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
11.4
334
2398
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
10.8
151
868
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
4.8
10.8
24
51
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
10.6
139
782
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
10.5
62
250
R99
ICPC
Respiratory disease other
4.7
10.5
24
52
L04AX01
ATC
azathioprine; systemic
3.7
10.5
33
92
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
+∞
10.4
10
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
10.3
60
241
F10.25
ICD-10 Finland
Alcohol dependence continuous use
5.4
10.2
20
38
N05BA02
ATC
chlordiazepoxide; systemic
3.9
10.0
29
76
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.9
9.9
29
77
0110X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, EPÄILTY]
+∞
9.4
9
*
0120A
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, BAKTERIOLOGISESTI VARMA]
+∞
9.4
9
*
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
9.4
9
*
J01FA06
ATC
roxithromycin; oral
1.6
9.3
284
2034
R50.9
ICD-10 Finland
Fever, unspecified
2.0
9.3
117
648
M05BA04
ATC
alendronic acid; oral
2.3
9.2
72
332
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
9.2
123
695
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.1
9.1
19
38
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
9.0
147
884
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.7
8.9
28
78
R03AC03
ATC
terbutaline; inhalant
2.0
8.8
94
491
Z20.1
ICD-10 Finland
Contact with and exposure to tuberculosis
14.2
8.7
14
10
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
3.8
8.7
26
70
J46
ICD-10 Finland
Status asthmaticus
3.8
8.4
25
67
A16.5
ICD-10 Finland
Tuberculous pleurisy, without mention of bacteriological or histological confirmation
+∞
8.3
8
*
0118A
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, BAKTERIOLOG.VARMA]
+∞
8.3
8
*
0119X
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, EPÄILTY]
+∞
8.3
8
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
8.3
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.2
163
1037
R06.0
ICD-10 Finland
Dyspnoea
1.7
8.0
205
1393
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.4
8.0
29
89
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.3
7.8
20
48
JN4AD
NOMESCO Finland
Body CT examination
2.1
7.7
76
384
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
45.5
7.7
9
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
7.7
34
118
J01AA02
ATC
doxycycline; systemic
1.6
7.6
527
4490
R03BA01
ATC
beclometasone; inhalant
1.9
7.6
105
598
J45.8
ICD-10 Finland
Mixed asthma
3.4
7.6
27
82
L04AA13
ATC
[U] leflunomide
4.3
7.5
19
45
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
80.9
7.4
8
*
A15
ICD-10 Finland
Respiratory tuberculosis, bacteriologically and histologically confirmed
+∞
7.3
7
*
A16.9
ICD-10 Finland
Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
+∞
7.3
7
*
A15.5
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, confirmed bacteriologically and histologically
+∞
7.3
7
*
A18.0
ICD-10 Finland
Tuberculosis of bones and joints
+∞
7.3
7
*
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
6.3
7.3
18
29
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
4.4
7.2
18
42
L88
ICPC
Rheumatoid/seropositive arthritis
3.1
7.1
29
96
R03BB02
ATC
oxitropium bromide; inhalant
4.3
7.0
18
43
N05CD07
ATC
temazepam; oral
1.8
7.0
120
730
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.7
6.8
35
132
A31.9
ICD-10 Finland
Mycobacterial infection, unspecified
40.4
6.8
8
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.6
6.7
39
157
V03AA01, ,
ATC
4.1
6.7
18
45
R03AC13
ATC
formoterol; inhalant
2.4
6.6
45
195
WNF00
NOMESCO Finland
Infection source and contact determination
10.1
6.5
12
12
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
3.6
6.5
21
60
A31.89
ICD-10 Finland
Other mycobacterial infections
70.4
6.4
7
*
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
5.6
6.3
17
31
0116A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA,BAKTER.VARMA]
+∞
6.3
6
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
6.3
6
*
A19.1
ICD-10 Finland
Acute miliary tuberculosis of multiple sites
+∞
6.3
6
*
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
6.3
6
*
A18.3
ICD-10 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands
+∞
6.3
6
*
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
26.9
6.2
8
*
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.2
6.2
24
77
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.0
6.2
26
88
R81
ICPC
Pneumonia
2.7
6.2
31
116
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
6.1
93
545
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
203
198
13.75
191.58
7.1
2.8
—
—
—
0
0
108
58
21.63
139.48
12.9
3.7
—
—
—
0
0
95
142
7.53
62.10
2.9
1.4
—
—
—
0
0
55
82
7.17
35.69
1.1
1.1
—
—
—
0
0
60
133
4.82
25.67
1.8
1.6
1.30
0.10
iu/ml
3.24
21
33
48
98
5.17
22.57
1.5
1.5
—
—
—
0
0
42
80
5.51
21.31
1.5
1.5
—
—
—
0
0
41
85
5.05
18.93
1.7
1.6
—
—
—
0
0
41
85
5.05
18.93
1.7
1.6
—
—
—
0
0
52
137
4.01
17.81
1.8
1.6
—
—
—
0
0
30
50
6.21
17.43
1.4
1.6
—
—
—
0
0
23
11
21.53
16.05
1.7
1.2
—
—
—
0
0
343
2326
1.88
15.63
12.2
5.6
2.82
2.87
%
0.13
325
2164
29
54
5.55
15.05
1.4
1.4
15.86
14.24
u/l
0.39
29
49
27
24
11.63
14.87
8.3
4.5
—
—
—
0
0
48
136
3.70
14.84
1.9
1.6
—
—
—
0
0
160
847
2.13
14.76
4.7
3.3
0.80
0.82
mmol/l
1.22
153
788
37
87
4.42
14.70
1.6
1.5
—
—
—
0
0
346
2392
1.84
14.49
12.3
5.8
26.18
26.15
%
0.01
328
2236
341
2351
1.84
14.38
11.9
5.6
58.17
58.42
%
0.12
324
2200
34
76
4.64
14.37
1.5
1.5
—
—
—
0
0
382
2749
1.81
13.79
11.1
6.2
9.91
12.07
umol/l
4.89
373
2599
25
44
5.85
13.75
1.3
1.2
1.74
—
iu/ml
—
7
0
56
190
3.11
13.07
1.7
2.0
43.96
37.43
u/l
1.40
47
164
26
51
5.25
12.76
1.8
1.8
—
—
—
0
0
50
162
3.24
12.60
1.7
1.7
—
212.50
—
0
8
27
56
4.97
12.46
1.8
1.7
—
—
—
0
0
171
1003
1.92
11.59
2.5
1.8
—
—
—
0
0
385
2885
1.70
11.16
15.5
8.7
4.43
4.29
e9/l
0.54
346
2522
133
729
2.01
10.93
6.4
5.6
1.07
1.03
mmol/l
0.74
124
658
36
105
3.55
10.69
1.8
1.6
—
—
—
0
0
25
58
4.43
10.11
1.7
1.5
—
—
—
0
0
25
58
4.43
10.11
1.7
1.5
—
—
—
0
0
21
25
8.61
10.10
1.2
1.2
—
—
—
0
0
21
47
4.57
8.88
1.7
1.6
—
—
—
0
0
21
47
4.57
8.88
1.7
1.6
—
—
—
0
0
21
47
4.57
8.88
1.7
1.6
—
—
—
0
0
35
120
3.01
8.07
1.3
2.0
11.67
13.10
mg/l
0.34
26
106
136
831
1.78
7.85
3.2
2.5
2.14
2.26
g/l
1.53
124
758
131
794
1.79
7.76
3.2
2.5
20.18
22.24
%
0.90
107
679
145
906
1.75
7.74
3.2
2.5
10.67
12.36
umol/l
2.36
135
832
55
243
2.36
7.74
1.7
1.2
122.30
335.80
u/ml
1.25
49
219
74
375
2.08
7.47
2.1
1.6
—
—
—
0
0
318
2432
1.54
7.43
8.2
5.9
1.20
1.21
mmol/l
1.22
294
2188
119
710
1.81
7.42
2.4
1.8
—
—
—
0
0
308
2348
1.53
7.25
6.0
4.8
33.30
34.79
g/l
4.08
280
2171
41
164
2.59
7.13
1.6
1.6
—
—
—
0
0
117
706
1.78
7.01
2.3
1.8
—
—
—
0
0
111
660
1.80
6.99
8.7
7.2
5.08
5.08
kpa
0.01
106
626
102
593
1.84
6.90
2.7
4.4
22.55
28.84
ug/l
0.13
84
509
87
482
1.91
6.84
1.7
2.6
66.52
66.09
g/l
0.20
74
430
110
660
1.78
6.71
8.7
7.2
1.27
1.30
mmol/l
0.02
96
513
223
1611
1.55
6.58
3.7
3.1
33.49
34.94
u/l
0.22
212
1534
16
27
6.03
6.33
1.8
1.7
—
—
—
0
0
38
156
2.51
6.29
1.4
1.6
—
—
—
0
0
335
2654
1.48
6.29
9.1
6.7
1.20
1.21
mmol/l
1.04
295
2219
88
512
1.82
5.94
2.4
2.2
0.19
0.20
g/l
0.54
83
470
25
85
3.01
5.89
1.8
1.5
—
—
—
0
0
14
22
6.46
5.88
1.9
1.8
—
—
—
0
0
14
22
6.46
5.88
1.9
1.8
—
—
—
0
0
436
3667
1.46
5.84
7.8
3.9
18.17
14.07
mm/h
4.07
410
3307
202
1464
1.52
5.76
2.9
2.1
3.09
3.15
mg/l
0.12
173
1240
14
23
6.18
5.71
1.9
1.7
—
—
—
0
0
15
27
5.65
5.70
1.8
1.7
—
—
—
0
0
463
3951
1.46
5.67
14.1
7.6
81.33
80.49
u/l
0.10
445
3671
24
84
2.92
5.40
1.3
1.2
2117.63
1347.61
e6/l
0.89
16
54
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
43
201
2.21
5.36
2.2
2.8
0.34
0.33
u/ml
0.06
22
109
57
300
1.98
5.22
11.0
8.6
24.48
24.58
mmol/l
0.08
57
287
21
71
3.01
5.02
1.9
1.6
—
—
—
0
0
10
13
7.78
4.86
2.3
2.8
43860.50
42538.46
ug/l
—
10
13
87
538
1.70
4.76
4.5
3.7
5.83
5.77
kpa
0.20
82
520
83
507
1.72
4.75
7.4
7.1
11.45
11.14
mmol/l
0.12
78
478
63
356
1.84
4.69
5.0
3.9
1.40
2.01
mmol/l
0.52
52
263
215
1638
1.44
4.64
2.9
2.5
62.25
59.25
u/l
0.32
203
1517
17
53
3.26
4.64
1.2
1.4
—
—
—
0
0
17
53
3.26
4.64
4.3
2.5
—
—
—
0
0
70
412
1.77
4.56
1.8
1.7
—
—
—
0
0
47
243
2.00
4.55
2.6
1.9
—
—
—
0
0
8
8
10.09
4.53
1.4
1.4
—
—
—
0
0
13
27
4.88
4.51
1.6
1.9
—
—
—
0
0
21
77
2.78
4.38
1.3
1.2
33850.33
27578.82
e6/l
0.08
12
44
85
536
1.66
4.33
4.8
3.7
2.32
2.09
mmol/l
0.28
70
430
328
2717
1.37
4.27
18.0
18.0
1.25
1.34
inr
0.96
80
772
23
90
2.61
4.25
1.4
1.4
—
—
—
0
0
79
494
1.67
4.16
2.0
1.8
1.70
1.57
%
0.76
67
423
11
21
5.30
4.15
2.2
2.0
1523.36
890.00
u/ml
0.47
11
21
23
92
2.55
4.08
1.1
1.1
—
—
—
0
0
229
1810
1.38
3.91
4.1
3.1
2840.45
2032.46
ng/l
1.26
206
1542
28
126
2.27
3.88
2.0
2.1
113.44
127.72
g/l
1.55
16
95
41
219
1.92
3.66
2.3
1.7
—
—
—
0
0
30
143
2.14
3.64
1.6
1.3
—
—
—
0
0
30
143
2.14
3.64
1.6
1.3
—
—
—
0
0
14
47
3.02
3.42
1.4
1.1
—
—
—
0
0
143
1066
1.42
3.39
2.1
1.7
1.29
1.34
mg/l
0.09
110
841
69
441
1.62
3.37
2.1
2.0
386.31
377.56
nmol/l
0.16
61
401
145
1092
1.41
3.24
5.1
4.0
888.73
301.89
ng/l
0.91
124
920
8
15
5.38
3.19
1.6
1.3
—
—
—
0
0
153
1171
1.39
3.10
2.0
1.8
1116.46
1157.62
nmol/l
0.23
113
875
203
1630
1.34
3.03
2.4
2.1
302.82
316.33
u/l
0.05
191
1525
363
3158
1.29
3.02
7.1
4.8
6.64
6.80
mmol/l
0.81
345
2963
14
52
2.72
2.90
1.9
1.8
—
—
—
0
0
252
2099
1.30
2.88
3.8
2.7
194.61
157.88
ug/l
0.83
234
1904
7
13
5.42
2.87
1.3
1.2
—
—
—
0
0
353
3081
1.28
2.78
5.4
3.1
60.29
52.98
u/l
0.70
330
2838
100
724
1.44
2.78
1.4
1.3
64.26
36.29
iu/ml
0.46
33
235
10
29
3.48
2.70
1.1
1.3
—
—
—
0
0
8
19
4.24
2.68
1.3
1.4
—
—
—
0
0
12
41
2.96
2.63
1.3
1.3
—
—
—
0
0
55
355
1.59
2.62
1.8
1.5
—
—
—
0
0
11
36
3.09
2.57
1.1
1.5
—
—
—
0
0
11
36
3.09
2.57
1.0
1.0
—
—
—
0
0
11
36
3.09
2.57
1.1
1.5
—
—
—
0
0
22
109
2.05
2.48
1.5
1.5
—
—
—
0
0
12
45
2.69
2.46
1.3
1.5
—
—
—
0
0
12
45
2.69
2.46
1.3
1.5
—
—
—
0
0
12
45
2.69
2.46
1.3
1.5
—
—
—
0
0
12
45
2.69
2.46
1.3
1.5
—
—
—
0
0
32
182
1.79
2.43
1.4
3.5
49.30
98.29
mg/l
0.76
25
146
32
182
1.79
2.43
1.4
3.5
28.95
33.43
mg/l
0.57
26
146
444
4836
0.80
2.38
5.1
5.1
2.52
2.61
mmol/l
1.48
405
4361
5
8
6.28
2.37
1.0
1.3
—
—
—
0
0
93
691
1.40
2.26
1.3
1.3
18.58
13.95
u/ml
0.18
27
267
25
135
1.88
2.24
2.5
1.4
0.23
0.23
g/l
0.01
25
130
19
93
2.07
2.23
1.4
1.3
4.26
3.88
mmol/l
0.34
19
85
5
9
5.58
2.21
1.2
1.4
—
—
—
0
0
5
9
5.58
2.21
1.0
1.4
—
—
—
0
0
170
1389
1.29
2.19
3.3
2.8
365.53
7158.41
umol/l
5.43
145
1189
37
227
1.66
2.19
1.7
2.5
3.77
3.66
g/l
0.17
27
199
37
227
1.66
2.19
1.7
2.5
8.04
7.45
g/l
1.00
27
199
37
227
1.66
2.19
1.7
2.5
—
—
—
0
0
507
5419
0.80
2.17
43.1
23.8
252.70
239.74
e9/l
3.22
500
5251
7
19
3.71
2.15
1.0
1.0
—
—
—
0
0
35
213
1.68
2.14
1.7
2.6
3.09
3.06
g/l
0.05
25
185
429
4662
0.81
2.10
4.7
4.5
1.47
1.42
mmol/l
1.43
389
4209
508
5422
0.80
2.10
43.0
23.8
4.32
4.43
e12/l
4.14
499
5235
8
25
3.22
2.10
4.8
4.0
114.25
89.44
nmol/l
—
8
25
9
31
2.93
2.07
2.0
1.6
—
—
—
0
0
508
5419
0.80
2.07
43.0
23.9
38.74
39.63
%
2.42
468
5010
12
50
2.42
2.03
1.3
1.6
—
—
—
0
0
257
2225
1.24
2.01
5.1
4.0
41.47
44.52
ng/l
0.21
191
1668
9
32
2.83
2.00
2.0
1.6
—
—
—
0
0
120
947
1.32
1.99
3.8
3.1
1.24
1.11
e6/l
0.11
77
566
435
4709
0.82
1.99
4.6
4.5
4.41
4.47
mmol/l
0.63
395
4283
24
134
1.82
1.97
2.5
2.3
—
—
—
0
0
155
1870
0.78
1.97
4.1
4.5
22.55
21.76
%
0.30
78
949
81
603
1.39
1.96
3.1
2.7
4.68
9.28
umol/l
5.09
71
535
32
195
1.67
1.96
1.3
2.8
0.35
1.03
g/l
0.81
21
166
201
2347
0.80
1.91
4.4
5.1
6.81
5.19
ug/l
0.15
178
2058
69
502
1.41
1.91
3.9
3.2
261.25
241.81
ng/l
0.13
60
455
153
1256
1.28
1.89
3.7
2.4
—
—
—
0
0
214
1827
1.24
1.89
3.4
3.4
2.33
2.35
mmol/l
0.56
181
1581
15
73
2.08
1.81
1.8
2.6
28.20
23.52
mg/l
—
5
18
8
29
2.78
1.79
1.3
1.2
—
—
—
0
0
9
36
2.52
1.74
1.3
1.1
—
—
—
0
0
9
36
2.52
1.74
1.3
1.1
—
—
—
0
0
38
250
1.55
1.74
1.2
1.2
129.28
142.20
iu/ml
0.06
15
90
232
2014
1.22
1.73
2.4
2.2
78.81
76.99
nmol/l
0.34
210
1766
5
13
3.86
1.71
1.0
1.2
—
—
—
0
0
10
40
2.52
1.67
2.0
1.5
—
—
—
0
0
10
40
2.52
1.67
1.2
1.3
—
—
—
0
0
16
83
1.95
1.65
1.5
1.3
35.89
213.04
miu/ml
—
7
35
18
314
0.56
1.64
1.4
1.8
—
—
—
0
0
113
910
1.29
1.63
4.0
3.3
1.61
1.58
e6/l
0.02
68
533
295
2635
1.20
1.62
3.3
2.7
—
—
—
0
0
8
32
2.52
1.60
1.6
1.2
—
82.00
—
0
5
29
183
1.61
1.59
1.3
1.2
—
—
—
0
0
108
1328
0.78
1.59
3.3
3.1
0.76
0.81
ug/l
0.38
72
913
6
20
3.02
1.58
1.0
1.3
28.17
22.50
%
—
6
10
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
26
2.71
1.58
1.0
1.2
—
—
—
0
0
29
184
1.60
1.56
1.3
2.6
36.81
36.77
g/l
0.01
19
156
231
2026
1.20
1.53
4.6
3.4
—
—
—
0
0
6
21
2.87
1.51
1.0
1.1
—
—
—
0
0
6
21
2.87
1.51
15.0
14.1
698.67
913.52
nmol/l
—
6
21
6
21
2.87
1.51
28.0
19.1
1483.83
1516.19
nmol/l
—
6
21
9
37
2.45
1.48
1.3
1.1
—
—
—
0
0
9
37
2.45
1.48
1.3
1.1
—
—
—
0
0
9
37
2.45
1.48
1.3
1.1
—
—
—
0
0
444
4737
0.84
1.47
5.0
4.7
5.90
6.06
mmol/l
1.65
400
4223
20
117
1.73
1.46
1.8
1.7
8040.00
16566.73
e6/l
0.93
15
89
264
2354
1.19
1.45
3.8
2.7
—
—
—
0
0
11
52
2.13
1.45
4.1
3.3
7.45
6.77
nmol/l
0.06
11
52
22
133
1.67
1.44
1.8
2.1
—
—
—
0
0
422
4514
0.85
1.41
4.1
4.1
1.21
1.28
mmol/l
1.04
379
4047
146
1234
1.23
1.40
3.4
2.6
4.38
4.34
e6/l
0.02
132
1106
22
134
1.66
1.40
1.7
1.4
330.38
276.73
ug/g
0.49
15
74
19
111
1.73
1.40
1.2
1.4
—
—
—
0
0
11
53
2.09
1.39
2.0
1.6
—
—
—
0
0
16
89
1.82
1.38
1.3
1.2
—
—
—
0
0
31
207
1.52
1.37
1.8
2.5
10.80
10.66
g/l
0.06
21
178
11
55
2.02
1.28
1.1
1.1
—
—
—
0
0
8
35
2.30
1.27
1.6
1.1
1.41
1.30
promille
—
8
26
8
36
2.24
1.24
2.0
1.5
—
—
—
0
0
15
85
1.78
1.23
1.3
1.1
355.11
281.70
u/ml
—
9
43
5
19
2.64
1.21
1.4
1.8
38.60
55.11
ug/l
—
5
19
66
517
1.30
1.21
2.6
2.5
6.73
7.08
ug/l
0.07
50
447
26
173
1.52
1.19
1.3
2.8
0.00
0.03
g/l
0.50
21
155
196
1732
1.18
1.18
4.6
3.5
41.92
121.80
e6/l
1.32
162
1366
63
493
1.30
1.17
3.3
2.4
32.62
34.29
u/l
0.17
55
410
19
118
1.63
1.15
3.8
2.4
13.80
15.69
%
1.05
11
63
5
20
2.51
1.15
2.0
3.0
84.40
99.35
%
—
5
20
372
3468
1.15
1.08
6.2
4.8
6216.80
3100.19
e6/l
—
10
68
179
1583
1.17
1.06
4.4
3.4
0.64
0.54
e6/l
0.24
146
1234
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
433
4566
0.88
1.01
5.8
6.1
40.61
40.70
mmol/mol
0.06
395
4165
16
99
1.63
1.00
4.8
3.1
4.40
4.60
e9/l
0.13
16
99
38
286
1.35
0.95
2.2
1.8
—
—
—
0
0
7
37
1.90
0.94
1.0
1.1
—
—
—
0
0
146
1650
0.86
0.92
4.0
3.8
13.76
9.92
mg/mmol
0.41
95
1069
16
102
1.58
0.91
5.7
3.6
59.19
59.97
%
0.10
16
102
75
622
1.23
0.90
1.4
1.4
—
—
—
0
0
42
324
1.31
0.90
2.2
1.9
—
—
—
0
0
31
228
1.38
0.90
1.4
1.3
—
—
—
0
0
6
30
2.01
0.87
1.0
2.1
—
—
—
0
0
11
64
1.73
0.86
1.2
1.4
—
—
—
0
0
13
80
1.64
0.85
1.1
1.1
—
—
—
0
0
6
31
1.94
0.84
1.7
3.1
—
—
—
0
0
501
5204
0.88
0.83
33.9
19.4
86.92
84.84
umol/l
0.30
501
5199
11
65
1.70
0.82
1.6
1.8
—
—
—
0
0
11
65
1.70
0.82
1.2
1.4
—
—
—
0
0
11
65
1.70
0.82
1.2
1.4
—
—
—
0
0
11
65
1.70
0.82
1.2
1.4
—
—
—
0
0
18
122
1.49
0.80
1.9
1.3
—
—
—
0
0
6
33
1.82
0.79
6.0
2.9
19.50
65.35
u/ml
—
6
33
11
66
1.68
0.79
1.2
1.4
—
—
—
0
0
11
66
1.68
0.79
1.2
1.4
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
1.11
—
0
16
49
398
1.25
0.74
4.6
4.0
95.10
90.69
ng/l
0.12
42
350
264
2460
1.11
0.71
6.0
5.4
0.00
0.00
estimate
-0.00
46
481
265
2470
1.11
0.71
4.5
4.0
0.00
0.00
estimate
0.50
51
528
5
26
1.93
0.70
1.0
1.3
—
—
—
0
0
5
26
1.93
0.70
1.0
1.3
—
—
—
0
0
503
5199
0.90
0.68
19.2
10.6
24.30
25.84
u/l
1.44
494
4972
133
1195
1.14
0.66
1.6
1.8
463.57
17659570.93
pmol/l
0.74
112
974
19
137
1.40
0.65
1.7
1.3
—
—
—
0
0
48
397
1.22
0.63
2.9
3.0
57.50
60.25
ml/min/173m2
0.21
24
167
500
5162
0.90
0.63
34.0
19.4
138.89
139.62
mmol/l
6.30
495
4997
146
1604
0.89
0.62
3.4
3.1
6.48
7.54
mmol/l
2.42
127
1327
5
30
1.67
0.61
2.6
2.5
—
—
—
0
0
501
5168
0.91
0.61
34.2
19.6
4.00
4.01
mmol/l
0.31
495
5000
15
105
1.44
0.60
1.3
1.6
774.00
283.19
mu/l
0.77
15
95
11
72
1.54
0.59
3.0
1.9
85.44
89.78
%
0.68
11
72
265
2495
1.10
0.57
4.6
4.0
0.00
0.01
estimate
0.50
46
468
12
81
1.49
0.57
1.4
1.5
—
—
—
0
0
21
159
1.33
0.56
1.3
2.8
0.00
0.00
g/l
-0.00
16
144
10
65
1.55
0.55
1.1
1.0
—
—
—
0
0
15
107
1.41
0.55
1.8
2.0
—
—
—
0
0
74
650
1.15
0.53
9.6
8.1
—
—
—
0
0
9
132
0.68
0.52
1.3
1.8
55.11
43.32
nmol/l
—
9
125
13
92
1.42
0.50
1.5
1.2
—
—
—
0
0
21
162
1.30
0.50
1.3
2.8
0.00
0.00
g/l
-0.00
16
144
6
41
1.47
0.50
2.3
2.1
—
—
—
0
0
121
1103
1.12
0.50
4.8
4.3
1.02
1.02
kg/l
0.09
21
165
20
155
1.30
0.47
4.5
2.9
1.56
1.76
mg/l
0.33
20
140
148
1373
1.10
0.44
1.9
1.6
18.87
20.42
nmol/l
0.62
130
1156
5
31
1.62
0.43
1.2
1.1
259.60
251.92
mg/l
—
5
26
15
113
1.33
0.43
1.1
1.2
—
—
—
0
0
5
32
1.57
0.42
1.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
3.2
—
—
—
0
0
0
17
0.00
0.40
0.0
3.2
—
—
—
0
0
5
34
1.47
0.40
8.4
1.8
—
—
—
0
0
70
630
1.12
0.38
4.5
4.6
34.08
32.19
%
0.56
49
409
237
2261
1.07
0.36
2.5
2.1
85.86
92.56
pmol/l
1.54
150
1198
6
45
1.34
0.34
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
17
139
1.23
0.29
3.3
3.9
38.67
30.95
mg/l
—
7
94
15
121
1.24
0.28
2.5
1.5
—
—
—
0
0
115
1080
1.08
0.28
3.7
3.2
2.46
2.45
mmol/l
0.36
98
936
10
76
1.32
0.28
5.6
4.0
358.30
343.92
umol/l
—
10
65
19
159
1.20
0.27
1.2
1.2
—
—
—
0
0
433
4416
0.95
0.25
5.0
4.4
1.83
1.99
mu/l
2.04
389
3932
22
189
1.17
0.24
2.7
2.7
154.30
50.68
u/ml
0.46
22
181
10
78
1.29
0.24
1.2
1.3
—
—
—
0
0
66
611
1.09
0.24
4.8
3.8
—
—
—
0
0
5
40
1.25
0.22
1.2
1.3
—
38.00
—
0
5
0
11
0.00
0.21
0.0
1.9
—
8.23
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
2.33
—
0
6
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
7
61
1.15
0.17
1.4
1.1
—
—
—
0
0
18
158
1.14
0.16
1.2
1.2
—
—
—
0
0
97
930
1.05
0.15
1.3
1.2
4.05
1.45
u/ml
0.44
22
225
11
129
0.85
0.15
2.2
1.8
—
—
—
0
0
7
88
0.79
0.14
1.4
1.4
—
—
—
0
0
457
4614
0.98
0.11
27.0
15.7
77.71
75.62
ml/min/173m2
0.94
388
3829
10
87
1.15
0.09
1.9
1.4
—
—
—
0
0
5
62
0.81
0.08
1.0
1.4
—
—
—
0
0
125
1229
1.02
0.05
1.7
1.6
1.28
1.35
mmol/l
0.44
110
1014
500
4981
1.01
0.04
32.6
16.6
27.40
26.87
mg/l
0.15
450
4044
352
3530
0.99
0.01
4.2
3.6
15.11
14.92
pmol/l
0.68
315
3123
43
437
0.98
0.01
1.4
1.4
—
—
—
0
0
193
1937
1.00
0.00
4.7
4.2
—
—
—
0
0
136
1366
0.99
0.00
5.2
4.1
0.00
0.01
estimate
0.50
43
461
14
144
0.97
0.00
1.5
2.4
130.50
100.26
ug/min
—
6
90
33
329
1.00
0.00
4.0
2.8
0.18
0.30
e6/l
0.56
33
322
9
95
0.95
0.00
1.2
1.9
202.56
224.17
pmol/l
—
9
87
5
49
1.02
0.00
1.4
2.3
—
—
—
0
0
20
200
1.00
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
27.33
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_RESP_TUBERCU_CONF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_RESP_TUBERCU_CONF | 2.229 [1.96, 2.54] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.076 |
During the follow-up period (1.1.1998 — 31.12.2019), 994 out of 2033 females with AB1_RESP_TUBERCU_CONF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_RESP_TUBERCU_CONF | 2.551 [2.23, 2.92] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 1865 out of 3273 males with AB1_RESP_TUBERCU_CONF died.
Mortality risk
Mortality risk for people of age
years, who have AB1_RESP_TUBERCU_CONF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.13% | 0.496% |
| 5 | 0.995% | 2.92% |
| 10 | 2.597% | 6.619% |
| 15 | 5.126% | 11.95% |
| 20 | 9.257% | 20.013% |
Relationships between endpoints
↥Index endpoint: AB1_RESP_TUBERCU_CONF – Respiratory tuberculosis, confirmed
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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