Retinal detachment with retinal break

H7_RETINALDETACHBREAK

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H33.0
  • Hospital discharge: ICD-9 3610
  • Hospital discharge: ICD-8 37602
  • Cause of death: ICD-10 H33.0
  • Cause of death: ICD-9 3610
  • Cause of death: ICD-8 37602

2 out of 7 registries used, show all original rules.

5557

4. Check minimum number of events

None

5557

5. Include endpoints

None

5557

6. Filter based on genotype QC (FinnGen only)

5399

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H33
Name in latin
Amotio/ablatio retinae cum ruptura

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 38578 16940 21396
Only index persons 34930 15487 19443
Unadjusted period prevalence (%)
Whole population 0.55 0.49 0.60
Only index persons 0.67 0.57 0.74
Median age at first event (years)
Whole population 61.36 62.21 60.64
Only index persons 60.64 61.44 60.01

-FinnGen-

Key figures

All Female Male
Number of individuals 5399 2283 3116
Unadjusted period prevalence (%) 1.17 0.81 1.43
Median age at first event (years) 61.04 59.71 62.02

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5557
Matched controls
55570
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H33
ICD-10 Finland
Retinal detachments and breaks
134.6
312.2
157
12
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.6
308.2
1221
3997
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
182.3
307.7
437
26
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
6.3
307.7
3536
12138
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
8.5
307.7
1138
1638
H33.3
ICD-10 Finland
Retinal breaks without detachment
1174.4
307.7
1269
14
CKD15
NOMESCO Finland
Injection of vitreous substitute
5506.5
307.7
512
*
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
250.4
307.7
522
23
CKD40
NOMESCO Finland
Endophotocoagulation of retina
4688.5
307.7
1456
*
H26.02
ICD-10 Finland
Presenil cataract
9.8
307.7
486
537
H43.1
ICD-10 Finland
Vitreous haemorrhage
42.2
307.7
764
209
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.1
307.7
1248
2184
CKC12
NOMESCO Finland
Photocoagulation of retina
282.9
307.7
1318
61
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
70.1
307.7
510
80
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
307.7
404
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
42.3
307.7
323
81
WX142
NOMESCO Finland
Sub-tenon anesthesy
50.6
307.7
270
56
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
1247.3
307.7
1400
15
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
1170.0
307.7
530
5
H25.1
ICD-10 Finland
Senile nuclear cataract
3.7
307.7
2520
10118
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
218.8
307.7
773
41
CKD20
NOMESCO Finland
Removal of vitreous body substitute
3145.9
307.7
587
*
H26.4
ICD-10 Finland
After-cataract
8.6
307.7
1654
2608
H26.2
ICD-10 Finland
Complicated cataract
39.8
307.7
494
136
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.6
307.7
607
1015
CJB10
NOMESCO Finland
Laser discission of secondary cataract
8.5
307.7
1387
2091
CKC10
NOMESCO Finland
Local photocoagulation of retina
263.3
307.7
503
21
S01EC01
ATC
acetazolamide; systemic
12.6
307.7
440
377
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
239.9
307.7
1319
72
Z96.1
ICD-10 Finland
Presence of intraocular lens
9.0
307.7
2223
3825
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
212.4
307.7
572
30
H35.4
ICD-10 Finland
Peripheral retinal degeneration
211.2
307.7
223
11
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
10.3
307.7
4188
12680
H33.5
ICD-10 Finland
Other retinal detachments
133.7
307.7
432
35
CKC60
NOMESCO Finland
Local buckling of sclera using implant
8954.1
307.7
783
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
307.7
736
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
307.7
465
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4503599627370496.0
307.7
5240
6
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
1533.7
307.7
1549
14
S01EA03
ATC
apraclonidine; ophthalmic
40.2
307.7
400
107
S01ED01
ATC
timolol; ophthalmic
9.0
307.7
636
790
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
58.0
307.7
244
44
WX002
NOMESCO Finland
Sedation and analgesia
3.4
307.7
1798
6877
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
1420.5
307.7
396
*
WX140
NOMESCO Finland
Parabulbar anesthesy
90.3
307.7
2391
461
S01ED51
ATC
timolol, combinations; ophthalmic
11.4
307.7
1673
2017
H43.8
ICD-10 Finland
Other disorders of vitreous body
4.5
307.7
971
2511
S01BC05
ATC
ketorolac; ophthalmic
6.6
306.3
520
854
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
34.4
304.3
193
58
S01EE01
ATC
latanoprost; ophthalmic
4.8
302.3
747
1729
S01FA01
ATC
atropine; ophthalmic
35.3
298.7
188
55
S01EA05
ATC
brimonidine; ophthalmic
8.4
292.3
395
503
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
271.4
1355
5085
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
11.8
262.8
272
241
XCK10
NOMESCO Finland
Photography of fundus of eye
4.0
257.7
823
2307
ZXA05
NOMESCO Finland
Left side
2.7
248.1
1934
9177
ZXA00
NOMESCO Finland
Right side
2.7
247.5
2065
10130
H34.8
ICD-10 Finland
Other retinal vascular occlusions
69.5
237.2
129
19
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.5
235.5
2847
16526
S01BC03
ATC
diclofenac; ophthalmic
7.8
218.4
309
414
XCH00
NOMESCO Finland
Eye pressure measurement
5.4
215.9
452
901
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
40.0
212.1
129
33
H52.1
ICD-10 Finland
Myopia
7.1
209.7
326
485
114
Kela drug reimbursment
Glaucoma
3.5
206.9
821
2645
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
1967.4
186.4
180
*
H35.37
ICD-10 Finland
Macular holes
377.7
183.7
184
5
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
180.2
172
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
11.0
175.6
189
177
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
5.0
172.6
390
828
H33.2
ICD-10 Finland
Serous retinal detachment
351.9
171.2
172
5
H20.1
ICD-10 Finland
Chronic iridocyclitis
13.6
170.1
160
121
XCD20
NOMESCO Finland
Photoangiography of eye
28.0
162.9
110
40
3745
FHL
Hard membrane girding, cerclage with coagulation
801.0
159.3
156
*
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
20.8
158.4
120
59
A10AA01, ,
ATC
9.4
153.3
185
203
ZXD05
NOMESCO Finland
Urgent procedure
2.2
152.2
1973
11245
CKC15
NOMESCO Finland
Panretinal photocoagulation
179.5
150.4
157
9
H27.0
ICD-10 Finland
Aphakia
27.3
149.8
102
38
H3603, E103,
ICD-10 Finland
+∞
148.6
142
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
308.5
147.3
149
5
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
146.8
2326
14263
S01EC04
ATC
brinzolamide; ophthalmic
4.3
146.5
399
982
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
146.5
140
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
494.0
146.1
145
*
H27.1
ICD-10 Finland
Dislocation of lens
20.8
145.2
110
54
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
144.4
138
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.3
143.4
161
160
A10AA02, ,
ATC
6.3
133.9
229
375
CKD60
NOMESCO Finland
Anterior vitrectomy
10.1
125.5
143
145
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
23.5
122.3
88
38
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
184.1
121.0
126
7
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.9
120.8
220
383
H40.0
ICD-10 Finland
Glaucoma suspect
2.9
120.2
613
2257
XCK00
NOMESCO Finland
Perimetry
3.3
118.6
484
1566
A10AB01
ATC
insulin (human); parenteral
5.9
117.4
214
373
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
1141.9
115.1
112
*
H36.01
ICD-10 Finland
Diabetic maculopathy
50.6
112.6
65
13
H35.36
ICD-10 Finland
Macular cyst
378.3
111.8
112
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
6.7
104.8
167
254
H3603, E113,
ICD-10 Finland
+∞
103.4
99
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
16.4
102.8
87
54
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.1
102.2
455
1547
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
6.6
102.1
167
261
S01FA04
ATC
cyclopentolate; ophthalmic
7.3
102.0
150
209
ZXE00
NOMESCO Finland
One hour or less
1.8
101.0
2229
14781
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
8.9
95.8
120
138
S01EE05
ATC
tafluprost; ophthalmic
3.7
94.9
317
899
H36.00
ICD-10 Finland
Diabetic background retinopathy
29.8
93.7
62
21
H54.4
ICD-10 Finland
Blindness, monocular
22.2
92.4
68
31
S01EC03
ATC
dorzolamide; ophthalmic
6.0
91.7
163
277
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
15.7
91.5
79
51
H25.8
ICD-10 Finland
Other senile cataract
2.3
88.0
755
3550
3747
FHL
Combined ablation and vitreous surgery with coagulation
861.8
86.9
85
*
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
20.9
84.8
64
31
S01BA04
ATC
prednisolone; ophthalmic
4.6
84.0
203
453
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
80.7
437
1651
H35.6
ICD-10 Finland
Retinal haemorrhage
208.0
79.5
82
*
ZXA10
NOMESCO Finland
Bilateral
2.0
76.3
1053
5910
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
76.3
2181
15249
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.0
75.6
357
1251
CKD30
NOMESCO Finland
Internal drainage of subretinal fluid
748.5
75.4
74
*
3643
FHL
Vitrectomy through pars Plana
135.3
75.1
80
6
H3601, E113,
ICD-10 Finland
+∞
73.1
70
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.0
72.2
210
540
H43.3
ICD-10 Finland
Other vitreous opacities
5.5
71.4
138
254
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
126.7
70.0
75
6
H04AA01
ATC
glucagon; nasal, parenteral
7.0
69.8
106
153
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
32.4
69.6
45
14
CKD25
NOMESCO Finland
External drainage of subretinal fluid
+∞
68.9
66
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.4
68.5
251
755
S01EX03, ,
ATC
4.3
68.2
177
418
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
67.8
65
*
H35.7
ICD-10 Finland
Separation of retinal layers
666.3
67.1
66
*
CKC75
NOMESCO Finland
Removal of cerclage from sclera
+∞
66.8
64
*
H44.2
ICD-10 Finland
Degenerative myopia
28.9
64.2
43
15
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
10.1
63.7
72
72
H3600, E103,
ICD-10 Finland
+∞
63.7
61
*
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
63.7
61
*
A10AB04
ATC
insulin lispro; parenteral
4.4
63.1
160
371
S01EE03
ATC
bimatoprost; ophthalmic
3.9
62.3
188
496
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.6
62.2
149
330
S01BA01
ATC
dexamethasone; ophthalmic
3.2
61.1
251
810
Z2221
NOMESCO Finland
Medical doctor
1.7
60.8
1465
9653
ZXD20
NOMESCO Finland
Day surgery
2.0
59.7
741
3982
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
22.2
59.7
44
20
H3601, E103,
ICD-10 Finland
+∞
58.4
56
*
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
24.3
57.6
41
17
T89
ICPC
Diabetes insulin dependent
3.5
55.1
191
554
S01EE04
ATC
travoprost; ophthalmic
3.9
55.0
164
429
S01AX11
ATC
[U] ofloxacin
3.1
54.0
237
795
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.3
53.3
107
204
H3600, E113,
ICD-10 Finland
+∞
53.2
51
*
H21.0
ICD-10 Finland
Hyphaema
11.9
52.3
53
45
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
51.9
491
2379
H26.1
ICD-10 Finland
Traumatic cataract
9.8
51.9
60
62
CA1ME
NOMESCO Finland
Ultrasound oculometry
7.5
51.7
74
100
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
15.1
51.1
45
30
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.9
51.0
151
393
H25.0
ICD-10 Finland
Senile incipient cataract
2.3
50.5
406
1840
S01BA07
ATC
fluorometholone; ophthalmic
4.3
48.3
127
303
TCG10
NOMESCO Finland
Removal of sutures from cornea
8.5
48.0
62
74
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
47.3
583
3112
A10AC01
ATC
insulin (human); parenteral
2.3
47.2
376
1697
H53.4
ICD-10 Finland
Visual field defects
3.6
46.7
155
437
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
11.8
46.3
47
40
3759
FHL
Other measure in this category
+∞
45.9
44
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
7.9
45.5
62
79
3661A
ICD-9 Finland
Cataract, Senile cataract
5.3
44.9
91
175
H16.0
ICD-10 Finland
Corneal ulcer
2.6
44.8
279
1126
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
16.9
44.5
37
22
H57.1
ICD-10 Finland
Ocular pain
3.0
44.3
204
703
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
9.1
44.2
54
60
E10
ICD-10 Finland
Type 1 diabetes mellitus
5.3
43.6
87
165
H35.8
ICD-10 Finland
Other specified retinal disorders
57.2
43.4
51
9
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
70.5
43.0
49
7
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.3
42.7
72
116
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
9.9
42.7
49
50
CFB00
NOMESCO Finland
Suture of conjunctiva
16.5
42.7
36
22
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
12.5
41.8
41
33
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
16.0
40.9
35
22
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
4.7
40.6
93
199
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.4
40.3
147
441
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.9
39.9
197
706
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
196.3
37.8
39
*
Z94.0
ICD-10 Finland
Kidney transplant status
5.0
37.7
81
164
H26.8
ICD-10 Finland
Other specified cataract
5.1
37.3
79
158
CKA10
NOMESCO Finland
Biopsy of vitreous body
49.2
36.6
44
9
H18.1
ICD-10 Finland
Bullous keratopathy
11.2
36.2
38
34
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
48.1
35.6
43
9
3742
FHL
Cryocoagulation under general anesthesia
+∞
35.4
34
*
XCH05
NOMESCO Finland
Eye pressure longterm registration
5.0
35.2
75
151
3660C
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA PRAESENILIS]
7.2
35.1
52
73
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.2
35.1
141
449
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.4
34.6
246
1055
S01ED02
ATC
betaxolol; ophthalmic
4.7
34.2
80
174
F05
ICPC
Visual disturbance other
2.8
34.2
172
623
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
7.6
33.9
48
64
Z3231
NOMESCO Finland
Registered nurse
1.5
33.9
1398
10213
ZX198
NOMESCO Finland
Other local administration
6.3
33.4
56
90
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
329.1
32.9
33
*
XCW10
NOMESCO Finland
Assessment of vision
4.5
32.6
80
181
CKD75
NOMESCO Finland
Retinotomy
+∞
32.3
31
*
H54.7
ICD-10 Finland
Unspecified visual loss
6.1
32.3
56
93
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
8.6
32.2
41
48
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
10.7
32.2
35
33
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.1
32.1
135
442
S01FA02
ATC
scopolamine; ophthalmic
4.5
31.9
77
172
3649
FHL
Other measure in this category
318.9
31.9
32
*
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2.5
31.7
203
830
CS494
NOMESCO Finland
Other visual field testing
2.9
31.4
148
517
1LA05, ,
NOMESCO Finland
+∞
31.3
30
*
CKD45
NOMESCO Finland
Endocryotherapy of retina
+∞
31.3
30
*
L04AA06
ATC
mycophenolic acid; systemic
3.3
31.0
115
349
127
Kela drug reimbursment
Transplant complication
3.7
30.1
96
264
H44.0
ICD-10 Finland
Purulent endophthalmitis
41.3
29.9
37
9
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
107.3
29.7
32
*
H43.9
ICD-10 Finland
Disorder of vitreous body, unspecified
4.7
29.4
68
147
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
29.2
28
*
L04AD02
ATC
tacrolimus; systemic
4.7
28.9
66
141
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
28.0
28.8
39
14
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
9.7
27.6
32
33
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
6.9
27.5
42
61
S01EB01
ATC
pilocarpine; ophthalmic
4.8
27.1
60
125
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
4.3
26.9
69
162
A10AD01
ATC
insulin (human); parenteral
3.9
26.8
80
210
H54.1
ICD-10 Finland
Severe visual impairment, binocular
32.0
26.8
35
11
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
+∞
26.1
25
*
CKD80
NOMESCO Finland
Retinectomy
+∞
26.1
25
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
60.3
26.0
30
5
H53.8
ICD-10 Finland
Other visual disturbances
3.6
25.6
83
231
Z94.7
ICD-10 Finland
Corneal transplant status
6.4
25.1
41
64
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
30.2
25.0
33
11
A10AB05
ATC
insulin aspart; parenteral
1.9
24.7
341
1881
H54.5
ICD-10 Finland
Severe visual impairment, monocular
6.0
24.6
43
72
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.7
24.6
128
473
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.6
24.5
58
128
H44.5
ICD-10 Finland
Degenerated conditions of globe
24.4
24.3
34
14
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
34.6
24.2
31
9
H40.12
ICD-10 Finland
Pigmentary glaucoma
9.7
24.1
28
29
137
Kela drug reimbursment
Uraemia requiring dialysis
4.6
24.0
57
126
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.7
23.3
54
117
A10AE05
ATC
insulin detemir; parenteral
2.1
23.2
237
1179
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
22.8
711
4856
B05DA
ATC
Isotonic solutions
4.9
22.7
49
100
F29
ICPC
Eye symptom/complaint other
1.7
22.6
425
2567
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.1
22.6
47
93
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
3.1
22.0
92
301
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
21.9
1271
9761
3626A
ICD-9 Finland
Other retinal disorders, Peripheral retinal degenerations
+∞
21.9
21
*
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
62.8
21.8
25
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
80.4
21.7
24
*
H40.8
ICD-10 Finland
Other glaucoma
6.0
21.6
38
64
T85.3
ICD-10 Finland
Mechanical complication of other ocular prosthetic devices, implants and grafts
115.5
21.6
23
*
H40
ICD-10 Finland
Glaucoma
3.6
21.3
70
197
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
23.2
21.2
30
13
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
3.3
21.1
79
242
CGF45
NOMESCO Finland
Suture of laceration of sclera
60.2
20.9
24
*
CKD85
NOMESCO Finland
Removal of subretinal membrane or band
+∞
20.8
20
*
3618X
ICD-9 Finland
Retinal detachments and defects, Other forms of retinal detachment
+∞
20.8
20
*
37601
ICD-8 Finland
Detachment of retina, Secundaria
+∞
20.8
20
*
H3603, E107,
ICD-10 Finland
+∞
20.8
20
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
6.2
20.6
35
57
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
4.1
20.6
56
138
B05DB
ATC
Hypertonic solutions
4.9
20.4
44
90
A12AA04
ATC
calcium carbonate; oral
3.1
20.1
85
280
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
4.1
20.1
55
136
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.2
20.0
79
250
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
6.6
20.0
32
49
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.8
19.9
60
159
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
6.8
19.9
31
46
H3602, E103,
ICD-10 Finland
+∞
19.8
19
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
19.8
19
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
19.8
19
*
A10AE04
ATC
insulin glargine; parenteral
1.6
19.6
430
2701
H44.1
ICD-10 Finland
Other endophthalmitis
29.0
19.6
26
9
H34.1
ICD-10 Finland
Central retinal artery occlusion
200.7
19.6
20
*
A11CC03
ATC
alfacalcidol; systemic
2.5
19.6
126
518
A98
ICPC
Health maint/preventive medicine
1.6
19.5
5074
48341
CHC05
NOMESCO Finland
Iridotomy
2.9
19.5
92
323
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
2.4
19.2
128
535
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
5.6
19.1
36
65
H26.9
ICD-10 Finland
Cataract, unspecified
2.7
19.0
98
361
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
70.1
18.7
21
*
WX402
NOMESCO Finland
General anaesthesia
1.4
18.6
963
7229
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.5
18.6
64
186
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
18.8
18.6
28
15
H50.2
ICD-10 Finland
Vertical strabismus
4.2
18.6
49
118
H31.0
ICD-10 Finland
Chorioretinal scars
100.4
18.6
20
*
A10AA03, ,
ATC
5.7
18.5
34
60
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
33.0
17.9
23
7
S01CA03
ATC
hydrocortisone and antiinfectives; ophthalmic
3.3
17.8
66
201
H17.8
ICD-10 Finland
Other corneal scars and opacities
6.7
17.8
28
42
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.6
17.8
101
391
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
+∞
17.7
17
*
3619X
ICD-9 Finland
Retinal detachments and defects, Unspecified retinal detachment
+∞
17.7
17
*
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
20.1
17.7
26
13
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.1
17.5
47
115
H16.9
ICD-10 Finland
Keratitis, unspecified
2.8
17.4
88
321
CJW99
NOMESCO Finland
Other operation on lens
28.9
17.4
23
8
CJF20
NOMESCO Finland
Removal of artificial lens
24.1
17.3
24
10
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
42.1
17.3
21
5
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.4
17.1
61
182
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
31.5
17.0
22
7
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
19.3
16.8
25
13
Z49.2
ICD-10 Finland
Other dialysis
4.2
16.7
44
106
CKC99
NOMESCO Finland
Other extraocular operations on vitreous body and retina
+∞
16.7
16
*
H35.9
ICD-10 Finland
Retinal disorder, unspecified
15.1
16.6
27
18
CHB65
NOMESCO Finland
Posterior synechiolysis
90.3
16.6
18
*
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
170.5
16.5
17
*
H26.3
ICD-10 Finland
Drug-induced cataract
4.4
16.3
40
91
H53.0
ICD-10 Finland
Amblyopia ex anopsia
4.1
15.8
43
106
Z49.0
ICD-10 Finland
Preparatory care for dialysis
3.2
15.8
62
196
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
5.2
15.8
32
62
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
15.6
15
*
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
+∞
15.6
15
*
NHQ40
NOMESCO Finland
Amputation of toe
2.7
15.6
82
306
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
2.8
15.5
77
279
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.9
15.1
180
947
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
23.4
15.1
21
9
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
4.1
15.1
40
97
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
14.7
1056
8314
V03AE02
ATC
sevelamer; oral
4.7
14.7
33
70
F28
ICPC
Limited function/disability (F)
4.1
14.7
40
99
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
14.6
14
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
14.5
772
5804
3852
FHL
Reoperation for another reason
150.4
14.5
15
*
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
150.4
14.5
15
*
3722
FHL
Cryocoagulation under general anesthesia
150.4
14.5
15
*
N18.0
ICD-10 Finland
End-stage renal disease
3.1
14.4
59
192
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
15.4
14.4
23
15
H53
ICD-10 Finland
Visual disturbances
3.8
14.4
43
114
E16.0
ICD-10 Finland
Drug-induced hypoglycaemia without coma
6.0
14.3
25
42
WX144
NOMESCO Finland
Subconjunctival anesthesy
3.0
14.2
61
204
H40.11
ICD-10 Finland
Low pressure glaucoma
2.3
14.2
104
455
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
14.4
14.0
23
16
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.5
14.0
33
73
F38
ICPC
Eye, Other laboratory test NEC
2.8
14.0
70
255
C02AC05
ATC
moxonidine; oral
1.8
14.0
228
1324
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
10.0
13.9
27
27
J01DB01
ATC
cefalexin; oral
1.3
13.8
4138
38619
H54.0
ICD-10 Finland
Blindness, binocular
17.6
13.8
21
12
TK800
NOMESCO Finland
Hemodialysis
2.3
13.8
107
480
R4110
NOMESCO Finland
Physiotherapy
1.3
13.7
1305
10672
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
13.6
1568
13127
3613A
ICD-9 Finland
Retinal detachments and defects, Retinal defects without detachment
+∞
13.5
13
*
H3603, E109,
ICD-10 Finland
+∞
13.5
13
*
H360, E103,
ICD-10 Finland
+∞
13.5
13
*
F82
ICPC
Detached retina
140.3
13.4
14
*
3711
FHL
Cyclodiateria or cryocoagulation
140.3
13.4
14
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
3.3
13.4
49
149
CS2P4
NOMESCO Finland
Optic nerve head imaging
3.4
13.2
47
140
A10AE06
ATC
insulin degludec; parenteral
2.1
12.9
126
618
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
9.3
12.9
26
28
S01AA01
ATC
chloramphenicol; ophthalmic
1.7
12.8
213
1244
SPAT1009
SPAT
Measurement of intraocular pressure
2.6
12.7
74
291
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
3.8
12.7
38
101
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
12.6
3303
30175
N02BE01
ATC
paracetamol; systemic, rectal
1.3
12.6
4585
43501
3662A
ICD-9 Finland
Cataract, Traumatic cataract
15.4
12.6
20
13
196
Kela drug reimbursment
Paricalcitol and cinacalcet
4.8
12.6
28
59
3721
FHL
Photo, laser or xenocoagulation under general anesthesia
+∞
12.5
12
*
CKD00
NOMESCO Finland
Puncture of vitreous body for decompression
130.3
12.4
13
*
N0832, E102,
ICD-10 Finland
130.3
12.4
13
*
TK820
NOMESCO Finland
Peritoneal dialysis
4.4
12.4
30
68
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.7
12.3
231
1396
3642
FHL
Anterior vitrectomy
26.7
12.0
16
6
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
26.7
12.0
16
6
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
18.1
12.0
18
10
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
5.2
12.0
24
46
3631
FHL
Setting up an artificial lens as the only procedure
21.3
12.0
17
8
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
8.7
12.0
25
29
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
3.1
11.8
49
161
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.6
11.7
249
1554
CDC00
NOMESCO Finland
Enucleation of eye
30.1
11.6
15
5
H18.8
ICD-10 Finland
Other specified disorders of cornea
3.7
11.5
36
99
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
3.2
11.5
44
138
H3603, H431,
ICD-10 Finland
+∞
11.5
11
*
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
11.5
11
*
3625
FHL
Extracapsular nuclear cataract removal
+∞
11.5
11
*
3611A
ICD-9 Finland
Retinal detachments and defects, Retinoschisis and retinal cysts
+∞
11.5
11
*
37609
ICD-8 Finland
Detachment of retina, Unspecified
+∞
11.5
11
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
11.4
567
4209
177
Kela drug reimbursment
Insulin glargine 300 U / ml
2.4
11.2
75
316
CFW99
NOMESCO Finland
Other operation on conjunctiva
5.5
11.2
21
38
S05.5
ICD-10 Finland
Penetrating wound of eyeball with foreign body
12.7
11.1
19
15
3639
FHL
Other measure in this category
12.7
11.1
19
15
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.0
11.0
117
593
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
3.5
11.0
36
102
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
10.0
11.0
21
21
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
10.0
11.0
21
21
S01KA02
ATC
hypromellose; ophthalmic
2.3
11.0
79
344
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
10.8
707
5473
Q12.0
ICD-10 Finland
Congenital cataract
17.8
10.7
16
9
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
4.6
10.7
25
55
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
60.1
10.6
12
*
Z2446
NOMESCO Finland
Social worker
1.6
10.6
248
1586
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.6
10.5
243
1549
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.6
10.5
230
1447
25008
ICD-8 Finland
Diabetes mellitus, Complicatio alia definita
10.0
10.5
20
20
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
9.2
10.5
21
23
H35.29
ICD-10 Finland
Other proliferative retinopathy
110.2
10.4
11
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
10.4
10
*
H3603, E106,
ICD-10 Finland
+∞
10.4
10
*
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
5.4
10.4
20
37
B03XA02
ATC
darbepoetin alfa; parenteral
2.1
10.3
97
471
CFD10
NOMESCO Finland
Repair of conjunctiva
9.6
10.2
20
21
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
23.4
10.2
14
6
S01EA02
ATC
dipivefrine; ophthalmic
4.6
10.0
23
50
WX001
NOMESCO Finland
Nonpharmacological sedation or pain relief
12.2
9.8
17
14
I79.2*E10.5
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
20.0
9.8
14
7
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
3.8
9.7
29
77
F99
ICPC
Eye/adnexa disease other
3.3
9.6
35
107
37002
ICD-8 Finland
Refractive errors, Myopia
11.4
9.5
17
15
CGF10
NOMESCO Finland
Suture of laceration of cornea
7.1
9.5
22
31
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
2.8
9.5
46
166
S01AD03
ATC
aciclovir; ophthalmic
1.8
9.5
150
867
N083, E102,
ICD-10 Finland
30.1
9.4
12
*
3665A
ICD-9 Finland
Cataract, After-cataract
30.1
9.4
12
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
9.4
9
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
9.4
9
*
H3602, E113,
ICD-10 Finland
+∞
9.4
9
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
21.7
9.3
13
6
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
2.6
9.3
52
202
KBV00
NOMESCO Finland
Insertion of stent into ureter
3.3
9.1
33
100
H26.01
ICD-10 Finland
Infantile, juvenile and presenile cataract
11.5
9.0
16
14
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
1.9
9.0
117
637
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
2.2
8.9
76
356
S01XA18
ATC
ciclosporin; ophthalmic
3.2
8.9
34
107
E0000UV, ,
ATC
1.2
8.8
1774
15606
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.6
8.8
184
1147
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
8.6
1431
12351
321
Kela drug reimbursment
Paricalcitol and cinacalcet
3.2
8.6
32
99
A10AD04
ATC
insulin lispro; parenteral
4.8
8.6
19
40
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
2.8
8.6
41
147
R42
ICD-10 Finland
Dizziness and giddiness
1.2
8.6
1003
8351
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
11.6
8.6
15
13
V03AE01
ATC
polystyrene sulfonate; oral
2.4
8.5
57
241
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
10.0
8.5
16
16
H18.4
ICD-10 Finland
Corneal degeneration
3.5
8.5
28
80
CG2S4
NOMESCO Finland
Photography of cornea
3.7
8.4
26
71
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
7.3
8.4
19
26
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
7.3
8.4
19
26
N0830, E102,
ICD-10 Finland
90.2
8.4
9
*
3656E
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POSTTRAUMATICUM]
+∞
8.3
8
*
H3601, E107,
ICD-10 Finland
+∞
8.3
8
*
H32.0*B58.0
ICD-10 Finland
Toxoplasma chorioretinitis
+∞
8.3
8
*
Q87.4
ICD-10 Finland
Marfan syndrome
10.7
8.3
15
14
CJF50
NOMESCO Finland
Removal and implantation of artificial lens in posterior chamber
14.5
8.2
13
9
E10.01
ICD-10 Finland
Insulin-dependent diabetes diabetic coma with hyperglycemia
14.5
8.2
13
9
H18.2
ICD-10 Finland
Other corneal oedema
6.5
8.2
20
31
C08CA01
ATC
amlodipine; oral
1.2
8.1
1926
17165
C08CA13
ATC
lercanidipine; oral
1.3
8.1
661
5270
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
6.8
8.0
19
28
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.1
8.0
74
359
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
7.9
2270
20540
Z71.8
ICD-10 Finland
Other specified counselling
1.2
7.9
1211
10365
CJE00
NOMESCO Finland
Phakoemulsification
13.0
7.9
13
10
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
1.8
7.8
114
646
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.5
7.8
240
1635
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
1.8
7.7
104
575
J01CA04
ATC
amoxicillin; systemic
1.2
7.6
3854
36463
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
3.3
7.6
28
86
H17.1
ICD-10 Finland
Other central corneal opacity
4.5
7.6
18
40
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.5
7.6
242
1657
N18.8
ICD-10 Finland
Other chronic renal failure
1.8
7.6
109
613
B03XA01
ATC
erythropoietin; parenteral
2.6
7.6
41
157
CJD30
NOMESCO Finland
Pars plana lensectomy
18.4
7.6
11
6
S18
ICPC
Laceration/cut
1.2
7.5
2173
19652
J05AB11
ATC
valaciclovir; oral
1.3
7.5
566
4468
H20.8
ICD-10 Finland
Other iridocyclitis
3.9
7.4
21
54
CJB99
NOMESCO Finland
Other operation on lens for secondary cataract
80.2
7.4
8
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
2.9
7.4
33
114
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
7.4
3180
29655
M14.6
ICD-10 Finland
Neuropathic arthropathy
13.4
7.4
12
9
H3600, E107,
ICD-10 Finland
+∞
7.3
7
*
H3603, H330,
ICD-10 Finland
+∞
7.3
7
*
37603
ICD-8 Finland
Detachment of retina, Retinoschisis
+∞
7.3
7
*
CFD00
NOMESCO Finland
Repair of conjunctiva without graft
+∞
7.3
7
*
H35.20
ICD-10 Finland
Proliferative vitreoretinopathy
+∞
7.3
7
*
CKC50
NOMESCO Finland
Transscleral laser therapy of retina
+∞
7.3
7
*
H3603, E119,
ICD-10 Finland
+∞
7.3
7
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.3
7.3
433
3305
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.6
7.3
153
957
S01AA12
ATC
tobramycin; ophthalmic
4.1
7.3
19
46
CA1AD
NOMESCO Finland
Orbita CT
6.2
7.2
18
29
H50.6
ICD-10 Finland
Mechanical strabismus
15.7
7.2
11
7
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
15.7
7.2
11
7
205
Kela drug reimbursment
Chronic hypertension
1.2
7.2
1357
11826
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.5
7.2
17
38
L28
ICPC
Limited function/disability (L)
1.2
7.2
789
6516
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
2.5
7.1
43
174
WX320
NOMESCO Finland
Spinalanesthesy
1.2
7.1
1090
9313
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
20.0
7.1
10
5
H26.0
ICD-10 Finland
Infantile, juvenile and presenile cataract
12.0
7.1
12
10
2507B
ICD-9 Finland
Diabetes mellitus, Diabetes with peripheral circulatory disorders[DIABETES MELLITUS CUM COMPLICAT ALIA ,TYYPPI I]
10.0
7.0
13
13
CF2S4
NOMESCO Finland
Photography of conjunctiva
7.0
7.0
16
23
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
7.0
723
5930
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
4.4
7.0
17
39
N40
ICD-10 Finland
Hyperplasia of prostate
1.2
6.9
1221
10570
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
13.8
6.9
11
8
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.4
6.8
335
2486
1LA04, ,
NOMESCO Finland
40.1
6.8
8
*
3793B
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[DISLOCATIO LENTIS]
40.1
6.8
8
*
E10.09
ICD-10 Finland
Insulin-dependent diabetes mellitus - With coma
40.1
6.8
8
*
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
40.1
6.8
8
*
CKB00
NOMESCO Finland
Puncture and evacuation of suprachorioidal fluid
40.1
6.8
8
*
37404
ICD-8 Finland
Cataract, Secundaria
16.7
6.7
10
6
J01FA10
ATC
azithromycin; systemic
1.2
6.7
2376
21762
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
3.1
6.7
26
83
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.5
6.7
202
1373
M86.6
ICD-10 Finland
Other chronic osteomyelitis
3.7
6.6
20
54
D64.9
ICD-10 Finland
Anaemia, unspecified
1.3
6.6
481
3777
CJB30
NOMESCO Finland
Excision of secondary cataract
10.0
6.5
12
12
S05.9
ICD-10 Finland
Injury of eye and orbit, unspecified
2.6
6.5
34
129
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
3.1
6.4
25
80
3768
FHL
Eye examination under general anesthesia
69.9
6.4
7
*
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
7.4
6.4
14
19
R63.4
ICD-10 Finland
Abnormal weight loss
1.5
6.4
162
1061
RJ521, ,
NOMESCO Finland
8.1
6.3
13
16
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
5.2
6.3
18
35
2505B
ICD-9 Finland
Diabetes mellitus, Diabetes with ophthalmic manifestations[NEUROPATHIA DIABETICA,TYYPPI I]
9.2
6.3
12
13
H59.8
ICD-10 Finland
Other postprocedural disorders of eye and adnexa
18.0
6.3
9
5
H28.0
ICD-10 Finland
Diabetic cataract
18.0
6.3
9
5
JL9AE
NOMESCO Finland
Ultrasound examination of pancreas transplant
+∞
6.2
6
*
H36.04
ICD-10 Finland
Severe diabetic ophthalmopathy
+∞
6.2
6
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
6.2
6
*
3602A
ICD-9 Finland
Disorders of the globe, Degenerative disorders of globe[MYOPIA MALIGNA]
+∞
6.2
6
*
H35.3
ICD-10 Finland
Degeneration of macula and posterior pole
+∞
6.2
6
*
H3603, H103,
ICD-10 Finland
+∞
6.2
6
*
H3603, E1100,
ICD-10 Finland
+∞
6.2
6
*
H3601, E106,
ICD-10 Finland
+∞
6.2
6
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
2.7
6.2
32
120
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
26.7
6.2
8
*
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
26.7
6.2
8
*
S01AX12
ATC
[U] norfloxacin
3.0
6.2
26
87
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.5
6.2
185
1254
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
2.6
6.2
34
132
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
6.2
67
346
L04AD01
ATC
ciclosporin; systemic
1.9
6.2
69
360
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
5.3
6.1
17
32
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.2
6.1
1102
9546
S97
ICPC
Chronic ulcer skin
1.4
6.1
250
1798
C09CA06
ATC
candesartan; oral
1.2
6.1
1007
8657
L17
ICPC
Foot/toe symptom/complaint
1.2
6.1
1214
10612
F93
ICPC
Glaucoma
2.8
6.1
28
99
G04CA02
ATC
tamsulosin; oral
1.2
6.1
1302
11449
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
2.2
6.1
48
220
RK321, ,
NOMESCO Finland
12.5
6.1
10
8
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.2
6.0
794
6677
171
Kela drug reimbursment
Degludekinsuliini
10.0
6.0
11
11
H43.0
ICD-10 Finland
Vitreous prolapse
6.7
6.0
14
21
L82
ICD-10 Finland
Seborrhoeic keratosis
1.2
6.0
778
6532
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.2
6.0
861
7302
M05BA04
ATC
alendronic acid; oral
1.3
6.0
348
2648

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5020
47069
1.69
28.70
21.0
18.2
3.98
3.99
mmol/l
1.91
4891
45874
5002
46943
1.66
27.40
20.7
18.1
139.59
139.68
mmol/l
1.64
4883
45813
5187
49280
1.79
25.57
25.4
22.7
91.55
91.44
fl
0.93
5108
48521
5187
49281
1.79
25.55
25.5
22.8
6.71
6.79
e9/l
1.28
5023
47769
5187
49284
1.79
25.51
25.5
22.7
4.46
4.48
e12/l
2.81
5027
47781
5186
49278
1.78
25.41
25.4
22.6
30.47
30.45
pg
0.25
5107
48518
5187
49291
1.79
25.40
25.7
22.9
134.84
135.69
g/l
3.69
5111
48536
5184
49264
1.78
25.24
25.5
22.8
241.83
243.99
e9/l
1.56
5042
47925
5181
49234
1.77
25.14
25.8
22.9
39.98
40.29
%
1.54
4830
45748
4828
45359
1.49
21.64
5.4
5.1
2.63
2.70
mmol/l
4.75
4406
41576
5031
47729
1.57
21.03
12.1
10.9
26.17
26.81
u/l
1.02
4840
45945
4890
46154
1.50
20.45
16.1
14.7
—
—
—
0
0
4725
44370
1.43
19.64
4.8
4.6
4.53
4.58
mmol/l
2.92
4319
40892
4130
37958
1.34
19.51
21.0
18.4
15.09
15.21
%
0.67
4062
37255
1710
13950
1.33
19.50
5.5
4.0
7.40
7.40
ph
0.05
328
2674
4366
40476
1.37
19.43
4.7
4.6
1.97
2.14
mu/l
1.19
3922
36685
1495
12001
1.34
18.95
4.6
4.0
86.21
87.37
%
0.99
1456
11717
2498
21511
1.29
18.93
7.6
6.0
1.21
1.21
mmol/l
0.65
2263
19592
4687
44035
1.41
18.64
4.8
4.6
1.44
1.43
mmol/l
1.29
4254
40311
3625
32824
1.30
18.32
4.2
4.0
—
—
—
0
0
2710
23647
1.29
18.27
8.6
6.8
1.21
1.21
mmol/l
0.86
2279
20075
4745
44711
1.42
18.24
17.6
15.5
25.04
25.81
mg/l
0.76
3874
35956
2393
20631
1.28
17.45
5.4
4.9
34.78
35.13
g/l
2.16
2209
19162
4673
44072
1.38
16.50
5.0
4.8
6.07
6.01
mmol/l
1.79
4205
39942
4538
42623
1.35
16.28
4.3
4.1
1.28
1.31
mmol/l
2.04
4067
38676
1946
16480
1.28
15.95
4.5
3.8
76.21
104.08
e6/l
1.22
1415
12002
1737
14507
1.29
15.89
4.0
3.4
77.50
86.57
e6/l
0.14
1342
11248
3652
33366
1.28
15.76
4.4
4.1
13.35
12.89
mm/h
0.99
3357
30741
2431
21201
1.26
15.44
6.8
6.4
8.89
8.81
%
0.54
2274
19764
1606
13331
1.29
15.28
3.9
3.3
0.38
0.45
e6/l
0.72
1232
10237
2558
22462
1.26
15.25
6.3
5.8
0.61
0.61
e9/l
0.13
2199
19271
2414
21087
1.26
14.95
6.6
6.1
2.92
2.87
%
0.51
2255
19626
985
7662
1.35
14.94
3.4
3.1
2.29
2.05
e6/l
0.37
538
4256
2347
20443
1.26
14.88
6.6
6.1
0.68
0.67
%
0.31
2195
18997
2561
22531
1.25
14.87
6.3
5.8
0.04
0.04
e9/l
0.84
2201
19336
2473
21677
1.25
14.81
6.7
6.2
26.44
27.08
%
2.02
2325
20243
501
3484
1.48
14.48
5.2
3.7
112.42
93.17
ng/l
3.01
437
2973
2435
21345
1.25
14.45
6.4
5.9
58.28
57.72
%
1.40
2289
19918
1544
12842
1.28
14.27
3.8
3.2
—
—
—
0
0
2266
19749
1.25
14.01
11.1
10.0
0.00
0.00
e9/l
0.39
1858
16091
2243
19532
1.25
13.95
2.1
2.0
95.10
93.84
pmol/l
0.62
1178
10356
2602
23036
1.24
13.93
6.3
5.8
1.91
1.91
e9/l
0.00
2283
20209
3866
35774
1.27
13.92
8.6
7.8
79.55
79.15
u/l
0.21
3674
33706
2396
21068
1.24
13.50
6.9
6.4
—
—
—
0
0
2040
17639
1.25
13.34
3.2
2.8
150.04
161.63
ug/l
0.99
1864
16181
2066
17903
1.25
13.21
2.4
2.2
78.27
78.09
nmol/l
0.10
1820
15929
2620
23297
1.24
13.19
6.4
6.0
0.20
0.20
e9/l
0.13
2268
20272
2911
26179
1.24
13.17
9.2
9.2
4.19
4.18
e9/l
0.04
2541
22747
1035
8247
1.31
13.11
3.3
2.9
1.40
1.08
e6/l
0.28
586
4800
4468
42206
1.30
12.97
6.6
5.9
40.58
40.07
mmol/mol
2.93
4101
38818
3061
27705
1.23
12.92
5.8
4.8
6.91
6.75
mmol/l
3.35
2892
26107
858
6724
1.33
12.16
2.3
2.0
—
—
—
0
0
2598
23214
1.22
12.06
18.6
16.6
1.31
1.32
inr
0.08
761
6580
42
124
3.41
12.03
5.8
4.5
—
—
—
0
0
1820
15699
1.24
11.78
3.8
3.5
2.35
2.35
mmol/l
0.12
1570
13687
1714
14695
1.24
11.72
2.2
2.2
199.72
223.53
u/l
0.57
1590
13739
134
701
1.93
11.53
1.8
1.3
99.13
117.09
u/ml
1.34
27
147
81
352
2.32
11.29
2.4
2.3
—
—
—
0
0
1164
9604
1.27
11.03
3.3
3.0
527.25
552.32
mosm/kgh2o
4.01
1005
8262
803
6326
1.31
10.89
8.5
5.6
1.06
1.03
mmol/l
2.29
749
5880
77
338
2.30
10.51
1.2
1.2
—
—
—
0
0
197
1193
1.68
10.44
3.4
2.7
1.84
1.59
mg/l
2.67
177
1089
3371
31156
1.21
10.31
4.8
4.3
—
—
—
0
0
144
801
1.82
10.29
1.8
1.3
—
—
—
0
0
378
2677
1.44
9.93
8.8
9.4
24.01
24.34
mmol/l
1.27
366
2595
1764
15379
1.22
9.87
4.4
3.7
13.79
8.31
mg/mmol
2.91
1142
9786
1058
8736
1.26
9.84
3.2
3.2
2.46
2.46
mmol/l
0.62
905
7632
3240
29904
1.20
9.79
5.0
4.6
1922.82
1340.44
e6/l
0.31
49
448
552
4181
1.36
9.76
2.7
2.6
65.75
66.22
g/l
0.70
496
3796
43
148
2.92
9.63
2.0
1.5
—
—
—
0
0
691
5426
1.31
9.53
2.1
1.8
—
—
—
0
0
51
194
2.64
9.49
23.4
25.6
99.00
113.05
ug/l
0.97
36
160
1717
15019
1.21
9.12
3.7
3.1
7.21
7.72
mmol/l
5.89
1455
12545
854
6935
1.27
9.07
3.4
2.5
2.22
2.29
g/l
2.95
798
6415
807
6517
1.28
8.96
3.5
2.5
22.79
22.70
%
0.07
699
5527
262
1767
1.51
8.84
1.6
1.5
—
—
—
0
0
1668
14594
1.20
8.76
3.9
3.1
402.83
393.35
mg/l
0.03
1112
9410
2685
24523
1.18
8.64
6.7
6.5
12.04
12.06
umol/l
0.02
2544
23354
931
7680
1.25
8.63
2.1
2.1
29.77
30.00
s
0.53
905
7460
997
8290
1.25
8.62
1.3
1.2
3.43
2.00
u/ml
0.88
255
2161
709
5662
1.29
8.58
2.8
2.5
1.80
1.76
%
0.42
620
4994
1359
11685
1.22
8.52
2.3
2.2
3.00
3.00
mg/l
0.02
1152
9951
24
62
3.88
8.40
1.3
1.2
56.31
137.64
ng/l
0.61
14
43
3514
32876
1.19
8.40
3.9
3.8
14.92
14.90
pmol/l
0.24
3130
29643
464
3504
1.35
8.36
2.6
2.4
—
—
—
0
0
202
1305
1.57
8.31
2.5
2.5
3.72
3.60
g/l
0.49
196
1235
561
4360
1.32
8.31
7.9
7.0
1.33
1.37
mmol/l
0.40
548
4239
1297
11127
1.22
8.28
1.6
1.5
20.06
20.19
nmol/l
0.11
1092
9513
1656
14540
1.20
8.28
3.3
3.1
1824.64
1492.24
ng/l
1.59
1440
12563
529
4081
1.33
8.25
10.6
8.3
—
—
—
0
0
241
1628
1.50
8.10
2.0
2.1
22.50
21.68
s
0.82
221
1443
899
7445
1.25
8.01
1.5
1.5
2.67
2.59
g/l
0.44
533
4474
649
5186
1.28
7.80
1.9
1.6
—
—
—
0
0
1141
9724
1.22
7.73
2.0
1.8
1.24
1.33
mg/l
0.53
896
7509
313
2246
1.42
7.69
6.8
3.8
23.89
24.21
mmol/l
0.96
304
2196
2044
18375
1.18
7.63
2.2
2.2
—
—
—
0
0
899
7484
1.24
7.62
3.4
2.5
12.68
12.84
umol/l
0.27
844
6971
32
107
3.00
7.60
1.1
1.0
—
—
—
0
0
73
360
2.04
7.57
1.2
1.1
—
—
—
0
0
1185
10163
1.21
7.50
3.2
2.7
4.12
4.66
e6/l
1.06
1081
9142
944
7916
1.23
7.46
3.3
3.3
0.82
0.81
mmol/l
0.30
884
7400
1328
11527
1.20
7.38
6.9
6.9
—
—
—
0
0
1387
12093
1.20
7.33
1.7
1.6
1.31
1.37
mmol/l
2.22
1158
10105
3902
37015
1.18
7.26
22.8
20.0
332.28
332.45
g/l
0.57
3870
36714
1664
14756
1.18
7.23
2.7
2.5
—
—
—
0
0
544
4298
1.29
7.13
2.9
2.5
35.11
50.48
u/l
0.76
462
3709
226
1549
1.48
7.11
2.3
2.1
36.74
37.66
g/l
1.33
194
1348
317
2319
1.39
6.99
1.9
1.7
1.48
1.58
g/l
1.10
279
1983
1111
9533
1.21
6.94
3.9
3.9
487.46
568.48
ng/l
0.18
924
7871
1454
12813
1.18
6.71
3.2
2.8
5489.23
4760.52
umol/l
0.24
1261
11163
1355
11879
1.19
6.64
3.1
3.1
0.80
0.78
ug/l
0.25
927
8141
261
1867
1.42
6.57
2.7
2.4
2.97
2.93
g/l
0.26
228
1671
2258
20634
1.16
6.53
5.3
5.0
3.13
3.42
ug/l
0.24
2026
18516
566
4545
1.27
6.53
11.6
6.9
11.46
10.17
mmol/l
4.10
544
4313
260
1863
1.42
6.49
2.7
2.3
10.45
10.10
g/l
0.53
228
1652
489
3859
1.29
6.48
2.3
2.3
379.13
372.11
nmol/l
0.33
459
3530
512
4078
1.28
6.31
1.8
1.5
—
—
—
0
0
2345
21544
1.15
6.20
2.8
2.6
—
—
—
0
0
1532
13634
1.17
6.19
4.8
4.4
—
—
—
0
0
536
4308
1.27
6.14
2.9
2.5
71.56
68.75
e9/l
0.79
382
3270
274
2003
1.39
6.11
2.7
2.3
7.38
7.40
g/l
0.04
242
1804
273
1999
1.38
6.03
2.7
2.3
3.68
3.65
g/l
0.12
242
1803
347
2642
1.33
5.97
1.5
1.4
—
—
—
0
0
32
123
2.61
5.95
1.0
1.0
—
—
—
0
0
1059
9192
1.19
5.73
1.8
1.7
1219.58
1153.60
nmol/l
1.28
799
6936
112
691
1.63
5.71
1.4
1.2
277.06
283.76
u/ml
0.09
84
421
151
1002
1.52
5.64
1.3
1.2
—
—
—
0
0
645
5358
1.23
5.52
1.5
1.5
—
—
—
0
0
1544
13862
1.16
5.44
3.4
3.2
—
—
—
0
0
3053
28722
1.14
5.40
3.3
3.2
56.16
53.83
u/l
0.56
2821
26511
1923
17548
1.15
5.38
3.6
3.5
5.82
5.77
ph
0.22
95
1088
545
4460
1.25
5.36
1.8
1.5
—
—
—
0
0
1821
16572
1.15
5.28
4.4
4.4
22.22
22.01
%
0.22
888
8364
160
1097
1.47
5.13
4.3
4.7
2.45
2.68
mmol/l
0.52
121
748
30
121
2.49
5.11
1.1
1.1
—
—
—
0
0
2357
21869
1.14
5.03
5.5
4.9
0.00
0.00
estimate
0.80
446
4048
1271
11307
1.16
5.01
2.7
2.4
—
—
—
0
0
480
3908
1.25
4.95
2.2
2.2
12.96
12.64
nmol/l
0.41
413
3469
174
1224
1.44
4.90
1.6
1.5
0.23
0.24
g/l
1.10
165
1158
638
5362
1.21
4.87
2.7
2.7
8.28
9.27
umol/l
0.67
561
4706
2355
21889
1.13
4.82
4.1
3.7
0.00
0.00
estimate
0.19
471
4330
712
6056
1.20
4.80
1.3
1.3
—
—
—
0
0
2015
18552
1.14
4.79
3.9
3.8
87.14
74.88
ng/l
0.12
1490
13542
547
4537
1.23
4.76
5.9
3.7
5.75
5.83
kpa
1.10
531
4400
454
3692
1.25
4.74
4.3
3.0
4.61
4.56
kpa
0.18
438
3567
539
4466
1.23
4.74
2.9
2.9
212.87
206.56
ng/l
0.12
502
4071
698
5935
1.20
4.72
7.4
7.1
12.36
12.19
kpa
0.38
666
5670
698
5936
1.20
4.71
7.4
7.1
5.01
5.09
kpa
1.71
665
5671
147
1010
1.47
4.70
4.8
2.9
—
—
—
0
0
695
5911
1.20
4.69
7.4
7.2
0.52
1.12
mmol/l
3.33
561
4658
2376
22124
1.13
4.68
4.1
3.7
0.00
0.00
estimate
0.11
422
3933
564
4705
1.22
4.64
5.9
3.7
7.38
7.37
ph
—
7
38
544
4523
1.22
4.63
6.0
3.7
1.35
1.98
mmol/l
3.80
470
3820
233
1749
1.35
4.49
2.2
2.3
405.97
629.93
ug/l
0.78
221
1657
118
785
1.51
4.44
4.6
3.0
—
—
—
0
0
176
1266
1.40
4.42
1.6
1.5
1.14
1.18
g/l
1.11
167
1197
356
2840
1.27
4.39
2.5
2.4
29.04
23.96
au/ml
0.22
22
174
263
2018
1.32
4.37
1.6
1.5
61.10
14.90
u/ml
—
5
51
154
1089
1.43
4.27
4.3
3.9
—
—
—
0
0
324
2567
1.28
4.24
1.3
1.3
36.53
56.28
au/ml
0.82
14
145
194
1432
1.37
4.19
3.4
3.3
—
—
—
0
0
1601
14634
1.13
4.14
3.4
3.3
34.20
36.57
u/l
0.68
1515
13832
113
758
1.50
4.12
1.6
1.9
4.83
4.87
mmol/24h
0.04
100
653
67
397
1.70
4.09
1.7
1.5
—
—
—
0
0
124
854
1.46
3.98
1.4
1.3
—
—
—
0
0
728
6310
1.18
3.95
1.2
1.2
—
—
—
0
0
212
1603
1.34
3.94
3.2
3.4
11.27
3.07
ratio
—
9
128
181
1337
1.37
3.91
1.3
1.4
265.30
269.55
ug/g
0.10
108
800
16
54
2.97
3.84
8.5
14.1
6.04
5.60
mmol/l
0.20
16
54
216
1645
1.33
3.83
3.5
3.4
63.32
94.66
mg/l
0.42
174
1340
646
5563
1.18
3.80
1.3
1.3
543.07
493.73
titre
0.27
137
1151
349
2834
1.25
3.74
9.5
9.8
—
—
—
0
0
71
442
1.61
3.63
1.5
1.3
—
—
—
0
0
214
1643
1.31
3.60
3.5
3.4
42.10
50.36
mg/l
0.43
172
1335
173
1288
1.35
3.59
4.5
4.4
7.42
7.42
ph
0.45
163
1160
156
1145
1.37
3.55
1.7
1.8
13.12
11.64
mg/l
1.06
148
1050
129
923
1.41
3.42
1.5
1.3
4.59
23.38
e6/l
2.13
96
716
35
180
1.95
3.42
1.1
1.0
—
—
—
0
0
129
925
1.40
3.39
1.5
1.4
995.11
1072.23
e6/l
0.06
99
756
616
5338
1.17
3.37
7.8
7.5
95.91
95.59
%
0.71
591
5143
145
1069
1.37
3.24
1.2
1.3
544.86
544.91
mg/l
0.00
140
1010
89
601
1.49
3.22
1.3
1.2
3.11
4.66
u/ml
0.99
44
248
504
4313
1.19
3.21
1.4
1.4
—
—
—
0
0
100
692
1.45
3.21
1.4
1.1
—
—
—
0
0
38
206
1.85
3.20
1.5
1.5
—
—
—
0
0
93
635
1.47
3.19
2.0
2.3
32.38
32.86
pg
0.54
93
630
463
3935
1.19
3.19
4.6
4.0
1.22
1.23
mmol/l
0.26
402
3486
93
638
1.47
3.13
1.7
1.9
89.49
89.26
%
0.15
93
631
128
931
1.38
3.12
1.2
1.2
3.98
3.80
mmol/l
0.81
121
868
22
98
2.25
3.12
1.4
1.8
7.94
8.83
mg/l
0.41
17
82
159
1198
1.34
3.10
1.2
1.2
—
—
—
0
0
57
352
1.63
3.07
1.2
1.2
170.00
130.00
titre
—
5
9
57
352
1.63
3.07
1.3
1.2
280.00
146.00
titre
—
6
65
527
4547
1.18
3.06
2.4
2.3
7.36
7.78
ug/l
0.22
460
3967
596
5197
1.16
3.03
1.4
1.3
—
—
—
0
0
147
1102
1.34
2.98
1.1
1.1
—
—
—
0
0
262
2123
1.25
2.93
2.6
2.8
—
—
—
0
0
141
1054
1.35
2.92
2.8
2.6
16.22
16.05
%
0.19
68
561
8
17
4.71
2.91
1.0
1.0
—
—
—
0
0
563
4903
1.16
2.91
8.4
8.0
120.01
121.82
g/l
1.19
551
4772
1531
14213
1.11
2.85
4.3
4.1
—
—
—
0
0
43
253
1.71
2.80
1.7
1.5
5.64
6.87
u/l
0.81
38
210
38
217
1.76
2.75
1.1
1.2
1.09
1.05
ratio
0.43
13
63
116
853
1.37
2.69
1.3
1.3
51.24
63.65
mmol/l
4.54
97
676
310
2591
1.21
2.61
2.0
1.9
1.62
1.36
g/l
0.48
284
2336
66
441
1.50
2.58
1.1
1.1
—
—
—
0
0
1279
11823
1.11
2.56
1.4
1.3
—
—
—
0
0
1145
10535
1.11
2.51
3.9
3.7
—
—
—
0
0
44
270
1.63
2.49
1.1
1.1
265.28
306.34
mg/l
1.02
39
236
9
220
0.41
2.42
19.0
18.2
900.67
1430.05
nmol/l
—
9
211
350
2984
1.18
2.39
1.2
1.2
—
—
—
0
0
281
2349
1.21
2.39
3.3
3.3
4.44
4.43
pmol/l
0.04
254
2059
32
182
1.76
2.39
1.2
1.3
157.03
171.48
mmol/24h
0.39
32
182
385
3314
1.17
2.35
2.9
2.7
10.88
10.48
g/l
0.60
350
3010
45
283
1.59
2.33
1.2
1.1
39.96
44.13
mg/l
0.39
36
238
78
552
1.42
2.32
2.8
2.5
1.64
1.35
g/24h
0.37
31
275
517
4563
1.15
2.27
2.4
2.2
0.20
0.21
g/l
0.50
472
4232
22
114
1.93
2.20
1.5
1.9
—
—
—
0
0
1570
14757
1.09
2.17
3.4
2.6
65.45
66.68
u/l
0.07
1445
13664
248
2070
1.21
2.17
2.0
1.9
—
—
—
0
0
9
214
0.42
2.17
15.6
12.9
439.89
840.05
nmol/l
—
9
199
19
94
2.02
2.15
1.3
2.1
921.11
413.33
e6/l
—
9
39
69
487
1.42
2.11
3.4
3.2
—
—
—
0
0
112
861
1.31
2.02
1.5
1.5
—
—
—
0
0
145
1153
1.26
2.01
2.5
2.1
247.08
110.95
ug/min
1.03
81
699
28
163
1.72
1.97
1.1
1.2
—
—
—
0
0
420
3696
1.15
1.96
4.5
4.1
—
—
—
0
0
150
1203
1.25
1.95
1.5
1.8
—
—
—
0
0
139
1107
1.26
1.92
1.6
1.6
—
—
—
0
0
97
745
1.31
1.80
1.3
1.5
33.18
32.12
g/l
0.34
89
671
112
877
1.28
1.79
6.5
1.4
0.83
0.84
nmol/l
0.05
93
734
13
60
2.17
1.77
2.4
2.1
28.62
32.30
mg/l
—
6
8
20
109
1.84
1.77
2.2
2.0
6.52
8.37
mmol/l
1.59
14
66
519
4666
1.12
1.76
1.9
2.2
128.30
150.31
ug/g
0.77
408
3704
190
1583
1.21
1.75
4.1
3.0
0.39
0.30
g/l
0.71
101
679
37
240
1.55
1.75
1.1
1.1
—
—
—
0
0
23
133
1.73
1.69
1.6
1.4
—
—
—
0
0
7
25
2.80
1.65
2.3
1.9
—
—
—
0
0
187
1569
1.20
1.63
1.2
1.2
0.30
0.94
u/ml
1.60
20
154
343
3022
1.14
1.62
4.6
3.3
125.84
129.08
g/l
1.81
336
2950
5
14
3.57
1.61
4.4
5.1
370.20
372.29
umol/l
—
5
14
33
214
1.55
1.59
1.4
1.7
9.05
10.66
umol/l
0.14
19
136
279
2428
1.16
1.57
3.8
3.5
—
—
—
0
0
53
380
1.40
1.56
2.8
2.2
10.92
11.18
%
0.18
53
380
199
1687
1.19
1.56
1.1
1.1
89.29
202.97
titre
—
7
39
83
640
1.30
1.54
1.3
1.5
12007.40
1879.48
e6/l
0.46
63
460
41
282
1.46
1.51
1.4
2.4
472.82
511.61
e6/l
0.25
28
237
1221
11520
1.08
1.51
3.9
3.4
—
—
—
0
0
132
1081
1.23
1.49
3.0
3.1
0.82
0.81
nmol/l
0.09
105
816
15
79
1.90
1.49
1.1
1.3
—
—
—
0
0
766
7096
1.09
1.48
1.2
1.3
32.51
35.21
iu/ml
0.20
251
2233
58
427
1.36
1.48
1.6
2.3
1.20
1.10
e9/l
0.50
47
386
72
550
1.31
1.44
2.1
2.1
—
—
—
0
0
46
327
1.41
1.44
1.2
1.2
—
—
—
0
0
134
1104
1.22
1.44
1.3
1.4
36.41
31.98
iu/l
0.75
120
940
5
16
3.13
1.44
13.0
4.9
—
—
—
0
0
39
270
1.45
1.41
1.4
2.4
0.24
0.23
e9/l
0.11
29
235
63
474
1.33
1.41
1.4
1.3
281.93
278.21
mosm/kgh2o
0.60
46
365
40
279
1.44
1.39
3.6
3.6
—
—
—
0
0
1549
14778
1.07
1.39
3.2
3.0
—
—
—
0
0
49
356
1.38
1.37
1.1
1.0
783.17
727.29
ng/l
0.34
41
232
6
23
2.61
1.36
3.2
3.3
—
—
—
0
0
75
583
1.29
1.34
1.4
1.5
129488.65
49259.32
e6/l
0.86
43
343
337
3012
1.13
1.32
2.9
3.0
—
—
—
0
0
86
682
1.27
1.32
7.0
6.6
12.35
11.98
mg/l
0.32
79
620
99
799
1.24
1.31
1.2
1.3
195.85
196.59
miu/ml
0.01
31
311
126
1507
0.83
1.26
12.6
10.2
—
—
—
0
0
85
679
1.26
1.25
1.1
1.1
—
—
—
0
0
8
36
2.22
1.24
1.3
1.3
—
—
—
0
0
1070
10122
1.07
1.23
1.7
1.7
36959502.15
32711039.48
pmol/l
0.07
855
8404
130
1088
1.20
1.23
2.5
2.7
31.04
35.04
umol/l
1.37
115
973
458
4184
1.10
1.23
1.5
1.5
—
—
—
0
0
5
19
2.63
1.21
1.8
1.0
—
—
—
0
0
5
19
2.63
1.21
1.0
1.0
—
—
—
0
0
48
356
1.35
1.21
1.1
1.0
502.82
305.98
ng/l
0.87
39
239
392
3556
1.11
1.21
4.6
4.2
0.74
0.26
%
0.39
115
1070
20
124
1.62
1.20
1.3
1.1
—
—
—
0
0
81
649
1.25
1.17
1.2
1.1
108.48
1176.99
iu/ml
0.62
20
141
38
273
1.39
1.17
1.9
2.0
535.86
490.50
min
1.09
22
211
126
1059
1.19
1.16
1.1
1.1
—
—
—
0
0
57
438
1.30
1.15
1.2
1.2
—
—
—
0
0
24
158
1.52
1.14
1.0
1.2
—
—
—
0
0
62
484
1.28
1.12
1.2
1.2
93.38
54.49
u/ml
—
8
32
44
327
1.35
1.12
1.0
1.1
7.72
3.03
u/ml
0.43
16
127
10
51
1.96
1.11
1.1
1.1
—
—
—
0
0
33
235
1.41
1.08
1.1
1.2
425.82
345.95
u/l
0.14
28
216
27
185
1.46
1.08
1.1
1.1
110.00
480.45
ng/l
—
8
42
92
757
1.22
1.07
2.4
2.2
—
—
—
0
0
87
713
1.22
1.05
1.1
1.1
—
—
—
0
0
6
123
0.49
1.05
3.0
2.3
—
—
—
0
0
9
46
1.96
1.03
2.0
1.4
50.33
41.78
umol/l
—
9
46
71
571
1.25
1.03
1.5
1.3
—
—
—
0
0
9
47
1.92
1.02
1.2
1.9
2.63
2.99
mmol/l
—
9
42
59
465
1.27
1.01
1.5
1.5
29.74
29.36
%
0.03
38
289
32
230
1.39
1.01
2.3
2.5
1694.38
1881.10
ml
0.54
24
197
7
132
0.53
0.98
5.1
2.2
0.56
1.12
ug/l
—
7
123
0
30
0.00
0.97
0.0
8.6
—
—
—
0
0
7
36
1.95
0.97
1.1
1.4
—
—
—
0
0
72
585
1.23
0.97
1.4
1.4
—
—
—
0
0
38
284
1.34
0.96
1.4
1.6
—
—
—
0
0
363
3328
1.10
0.95
1.5
1.4
—
—
—
0
0
230
2059
1.12
0.95
1.3
1.2
—
—
—
0
0
144
1252
1.15
0.93
3.5
3.6
—
—
—
0
0
22
150
1.47
0.92
1.3
2.1
26.27
30.89
%
0.84
22
136
92
771
1.20
0.92
2.0
1.4
—
—
—
0
0
76
625
1.22
0.92
1.9
2.3
—
—
—
0
0
519
4841
1.08
0.92
5.4
4.3
—
—
—
0
0
36
269
1.34
0.92
1.9
2.7
33.68
38.06
%
0.53
19
154
21
142
1.48
0.92
1.0
1.1
1650.81
1607.13
miu/ml
0.08
21
142
340
3115
1.10
0.92
4.1
3.5
7.41
7.42
ph
0.11
46
382
119
1021
1.17
0.91
1.3
1.2
3.97
6.88
u/ml
0.88
19
172
45
348
1.30
0.91
1.2
1.4
0.23
0.25
nmol/l
0.14
33
259
42
322
1.31
0.91
1.1
1.1
30.82
35.09
mmol/l
0.80
37
268
43
331
1.30
0.90
1.5
2.3
7.31
6.90
mmol/l
0.39
34
227
33
244
1.35
0.90
2.2
2.1
16.00
220.74
ug/min
—
9
61
393
3628
1.09
0.90
4.3
4.0
0.61
0.74
%
0.52
129
1286
251
2267
1.11
0.90
1.2
1.2
—
—
—
0
0
238
2638
0.90
0.90
1.3
1.3
—
—
—
0
0
14
218
0.64
0.88
3.2
3.7
—
—
—
0
0
68
556
1.23
0.88
1.4
1.6
—
—
—
0
0
183
1625
1.13
0.88
1.1
1.1
—
—
—
0
0
63
511
1.24
0.88
2.0
2.0
4263.32
2326.33
u/l
0.19
23
186
16
103
1.55
0.87
1.3
1.3
—
—
—
0
0
107
915
1.17
0.87
1.7
1.5
—
—
—
0
0
117
1008
1.16
0.87
1.3
1.2
33.91
3.00
u/ml
—
9
106
285
2600
1.10
0.85
2.6
2.4
—
—
—
0
0
92
779
1.18
0.84
1.4
1.5
—
—
—
0
0
16
104
1.54
0.84
1.1
1.2
1.48
1.66
mmol/l
—
9
65
72
596
1.21
0.84
1.5
1.5
59.51
61.37
%
0.15
45
374
23
162
1.42
0.84
2.1
1.8
39.96
58.52
ug/l
2.07
23
155
157
1387
1.14
0.83
1.4
1.2
—
—
—
0
0
125
1087
1.15
0.83
1.3
1.2
60.08
34.94
u/ml
—
8
58
19
129
1.47
0.83
1.5
1.7
—
—
—
0
0
58
470
1.24
0.83
1.1
1.1
15.56
3.79
u/ml
0.77
26
217
18
121
1.49
0.82
1.5
2.0
—
—
—
0
0
40
310
1.29
0.82
1.1
1.3
—
—
—
0
0
40
310
1.29
0.82
1.7
1.7
—
—
—
0
0
61
499
1.22
0.80
3.0
2.4
—
—
—
0
0
168
1495
1.13
0.80
1.6
1.6
—
—
—
0
0
110
951
1.16
0.80
1.8
1.7
5.69
4.62
iu/l
0.39
41
311
6
33
1.82
0.79
1.3
1.3
—
—
—
0
0
0
25
0.00
0.79
0.0
1.4
—
4.06
—
0
25
342
3164
1.09
0.77
4.1
3.5
5.08
5.16
kpa
1.21
330
2994
85
722
1.18
0.77
1.4
1.3
—
—
—
0
0
10
59
1.70
0.75
1.1
1.3
—
—
—
0
0
56
458
1.22
0.75
1.1
1.1
3.61
1.04
u/ml
0.36
24
184
403
3760
1.08
0.75
4.6
4.2
0.13
0.12
%
0.07
127
1269
5
24
2.08
0.74
1.6
1.4
60.22
14.78
pmol/l
—
5
17
9
54
1.67
0.74
1.7
1.5
—
—
—
0
0
73
615
1.19
0.73
1.9
1.4
50.52
62.47
mu/l
0.41
60
545
107
931
1.15
0.73
3.3
2.7
—
—
—
0
0
131
1159
1.13
0.71
1.2
1.3
—
—
—
0
0
35
273
1.28
0.71
1.4
1.2
—
—
—
0
0
74
628
1.18
0.70
1.5
1.3
0.18
0.27
nmol/l
—
8
47
7
41
1.71
0.70
1.1
1.3
—
8.02
—
0
5
36
283
1.27
0.69
1.0
1.0
6.32
0.28
u/ml
—
10
94
246
2258
1.09
0.69
4.1
3.6
—
—
—
0
0
50
409
1.22
0.69
1.1
1.1
2.96
1.32
u/ml
0.55
23
203
424
3982
1.07
0.67
4.5
4.1
0.94
0.97
%
0.07
147
1481
20
144
1.39
0.67
1.1
1.1
—
—
—
0
0
32
249
1.29
0.67
16.0
11.9
—
—
—
0
0
17
119
1.43
0.66
8.8
6.7
—
—
—
0
0
143
1279
1.12
0.66
4.5
4.2
—
—
—
0
0
44
357
1.23
0.66
1.0
1.1
4.52
2.12
u/ml
0.45
21
164
114
1006
1.14
0.66
1.8
1.9
202.75
198.77
pmol/l
0.18
106
950
132
1176
1.13
0.66
1.2
1.2
90.67
149.38
titre
1.04
15
97
88
763
1.16
0.65
1.2
1.2
29.39
47.28
u/ml
—
9
76
940
9762
0.96
0.64
4.6
4.2
1.02
1.02
kg/l
0.80
151
1462
61
514
1.19
0.64
1.1
1.2
—
—
—
0
0
13
87
1.50
0.63
4.9
7.1
—
—
—
0
0
75
645
1.17
0.62
1.2
1.3
—
—
—
0
0
27
347
0.78
0.62
1.7
2.5
—
—
—
0
0
36
288
1.25
0.62
3.2
2.9
—
—
—
0
0
10
63
1.59
0.61
1.1
1.2
2.56
532007.46
nmol/l
—
5
50
20
147
1.36
0.61
1.0
1.2
—
—
—
0
0
14
96
1.46
0.61
1.1
1.1
—
—
—
0
0
29
226
1.28
0.61
1.6
1.7
1.61
2.88
u/field
0.52
23
153
67
573
1.17
0.60
1.3
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
55
463
1.19
0.59
1.2
1.2
—
—
—
0
0
131
1178
1.11
0.58
1.2
1.2
—
939.71
—
0
34
174
1589
1.10
0.57
1.6
1.7
—
—
—
0
0
22
167
1.32
0.56
1.4
1.9
—
—
—
0
0
49
412
1.19
0.55
1.3
1.3
1.60
1.58
nmol/l
0.04
41
374
12
171
0.70
0.54
3.5
3.7
46.46
55.02
%
0.64
12
165
374
3531
1.06
0.54
4.6
4.7
—
—
—
0
0
6
38
1.58
0.54
3.0
1.7
—
—
—
0
0
19
142
1.34
0.54
1.2
1.2
34.00
39.30
g/l
0.89
12
73
617
5910
1.05
0.53
4.9
4.6
34.09
32.29
%
3.25
425
3999
65
562
1.16
0.53
1.4
1.5
—
—
—
0
0
67
582
1.15
0.52
1.6
1.3
260.96
299.03
pmol/l
0.59
57
489
150
1371
1.10
0.51
1.4
1.4
—
—
—
0
0
559
5351
1.05
0.51
4.0
4.2
37.46
23.26
ug/l
0.56
441
4455
25
197
1.27
0.51
2.6
2.7
—
—
—
0
0
41
488
0.84
0.50
1.2
1.3
9586.93
103042.41
e6/l
2.55
30
335
24
189
1.27
0.49
1.7
2.1
—
—
—
0
0
17
128
1.33
0.47
1.2
1.1
—
—
—
0
0
17
128
1.33
0.47
1.2
1.1
—
—
—
0
0
17
128
1.33
0.47
1.2
1.1
—
—
—
0
0
7
47
1.49
0.47
2.4
2.2
12.33
17.98
umol/l
—
7
47
10
68
1.47
0.47
1.3
1.4
—
—
—
0
0
7
48
1.46
0.46
1.1
1.0
—
—
—
0
0
41
346
1.19
0.46
4.2
5.3
247.10
50.42
u/ml
—
7
104
258
2425
1.07
0.46
4.7
3.4
24.50
25.22
mmol/l
2.79
253
2348
134
1227
1.09
0.45
2.6
2.7
—
—
—
0
0
8
118
0.68
0.45
1.3
1.7
—
—
—
0
0
111
1008
1.10
0.45
1.1
1.1
14.00
7.58
u/ml
0.39
12
102
36
302
1.19
0.44
1.1
1.0
—
—
—
0
0
18
139
1.30
0.43
1.6
1.6
1.41
0.64
mmol/l
0.24
18
130
5
31
1.61
0.43
1.0
1.1
0.80
0.05
u/ml
—
5
31
60
527
1.14
0.42
11.7
5.7
7.75
7.32
mmol/l
0.39
49
446
57
499
1.14
0.42
1.4
1.5
—
—
—
0
0
12
87
1.38
0.42
1.8
1.7
111.25
147.84
ng/l
0.49
12
87
25
203
1.23
0.42
12.7
5.9
65.26
64.21
mg/l
0.03
19
142
57
501
1.14
0.41
1.1
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.13
—
0
5
5
34
1.47
0.40
1.6
1.4
—
—
—
0
0
258
2439
1.06
0.40
1.3
1.3
293.96
228.16
u/ml
0.29
237
2230
62
549
1.13
0.40
1.1
1.1
2.28
2.01
u/ml
0.09
27
284
17
216
0.79
0.40
1.2
1.1
—
—
—
0
0
7
101
0.69
0.39
2.0
1.5
—
—
—
0
0
208
1955
1.07
0.39
4.6
3.8
24.49
24.92
mmol/l
1.28
192
1772
7
105
0.67
0.39
2.6
2.7
—
119.81
—
0
14
200
1878
1.07
0.39
2.8
3.5
14065.99
1704.45
u/ml
0.43
159
1609
45
391
1.15
0.38
2.2
2.1
846.81
636.53
ml
1.14
26
270
39
452
0.86
0.38
3.2
3.0
69.93
49.76
mg/l
0.18
27
340
38
326
1.17
0.38
1.1
1.2
—
—
—
0
0
9
67
1.34
0.38
1.1
1.2
42.51
48.58
mg/l
—
9
58
8
116
0.69
0.36
1.0
1.0
—
—
—
0
0
32
272
1.18
0.36
1.2
1.3
0.25
1.23
u/ml
1.80
19
151
41
356
1.15
0.36
1.8
1.4
1.12
1.27
promille
0.26
34
276
34
291
1.17
0.35
1.1
1.1
—
—
—
0
0
16
201
0.80
0.35
1.6
1.7
2.51
6.24
nmol/l
0.94
16
166
1223
11979
1.03
0.35
4.6
4.1
0.00
0.00
estimate
1.60
426
3853
19
153
1.24
0.35
1.0
1.1
1.59
0.41
u/ml
—
5
48
17
135
1.26
0.35
1.4
1.4
76.65
266.13
nmol/24h
1.24
17
135
219
2073
1.06
0.34
6.3
4.7
—
—
—
0
0
31
264
1.18
0.34
1.5
2.0
—
—
—
0
0
22
181
1.22
0.34
1.5
1.5
—
—
—
0
0
36
311
1.16
0.34
1.8
1.6
111.58
87.97
umol/l
0.50
36
311
22
265
0.83
0.34
1.5
1.9
—
—
—
0
0
62
557
1.11
0.33
1.5
1.3
—
—
nmol/l
—
0
0
70
634
1.11
0.33
4.0
4.9
342.28
359.27
umol/l
0.47
57
541
121
1126
1.08
0.32
2.4
2.2
129.58
128.25
g/l
0.26
88
799
11
83
1.33
0.32
1.1
1.1
—
5.58
pmol/l
—
0
14
21
174
1.21
0.31
1.5
1.4
—
—
—
0
0
54
485
1.11
0.30
1.1
1.1
5.94
2.90
u/ml
0.29
28
195
687
6692
1.03
0.30
1.2
1.2
12.31
12.97
u/ml
0.08
228
2504
22
184
1.20
0.30
1.8
2.2
314.47
5068.52
e6/l
0.59
15
129
21
175
1.20
0.30
1.4
1.4
—
—
—
0
0
300
2881
1.04
0.29
1.2
1.2
—
—
—
0
0
129
1210
1.07
0.29
1.6
1.6
13927.46
15435.00
e6/l
0.15
90
869
99
920
1.08
0.28
1.2
1.3
10.30
9.55
u/l
0.18
80
744
58
526
1.10
0.28
1.2
1.2
—
—
—
0
0
28
323
0.87
0.28
1.8
1.7
—
—
—
0
0
473
4589
1.03
0.28
1.5
1.5
—
—
—
0
0
8
63
1.27
0.27
1.6
1.6
—
—
—
0
0
96
893
1.08
0.27
1.7
1.7
374.21
300.38
mu/l
0.73
89
833
21
177
1.19
0.27
1.2
2.3
69.83
161.16
umol/l
1.82
12
94
67
614
1.09
0.27
2.0
2.1
22.17
23.33
mg/l
0.08
18
139
414
4010
1.04
0.27
4.1
3.5
—
—
—
0
0
16
131
1.22
0.27
1.4
1.5
—
—
—
0
0
21
247
0.85
0.27
1.1
1.1
—
—
—
0
0
37
330
1.12
0.25
1.5
1.3
—
—
—
0
0
225
2161
1.04
0.24
4.8
5.1
1.58
1.64
%
0.54
211
2023
245
2359
1.04
0.23
1.2
1.2
114.79
136.02
iu/ml
0.44
86
849
5
38
1.32
0.23
1.6
1.2
—
—
—
0
0
10
124
0.81
0.21
1.1
1.1
—
—
—
0
0
19
163
1.17
0.21
1.5
1.2
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
92.95
—
0
10
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
31
277
1.12
0.21
1.1
1.0
—
—
—
0
0
81
863
0.94
0.21
3.4
3.6
1.80
1.76
%
0.03
74
753
39
429
0.91
0.21
1.2
1.2
380.00
349.39
nmol/l
0.36
30
353
173
1659
1.04
0.21
4.7
6.0
1.34
1.34
mmol/l
0.02
154
1472
0
13
0.00
0.21
0.0
1.2
—
4.53
—
0
13
10
123
0.81
0.20
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
16
136
1.18
0.20
1.3
1.7
12.70
13.75
g/l
0.19
11
104
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
83
783
1.06
0.18
1.4
1.4
—
—
—
0
0
7
58
1.21
0.18
6.3
4.0
39.14
53.57
ug/min
—
7
46
15
174
0.86
0.17
1.1
1.3
56.30
55.00
%
0.05
15
147
8
69
1.16
0.16
1.0
1.2
—
—
—
0
0
11
92
1.20
0.16
1.1
1.1
—
—
—
0
0
142
1368
1.04
0.15
1.1
1.1
—
—
—
0
0
56
526
1.07
0.15
1.3
1.2
—
—
—
0
0
14
161
0.87
0.15
1.0
1.1
—
—
—
0
0
219
2131
1.03
0.14
4.8
5.1
0.85
0.89
%
1.01
204
2001
22
198
1.11
0.14
2.2
2.4
—
—
—
0
0
72
757
0.95
0.14
2.3
2.4
—
—
—
0
0
72
757
0.95
0.14
1.5
1.5
179.83
203.80
pmol/l
0.12
72
741
19
170
1.12
0.13
1.3
1.3
4.00
242.29
ug/l
—
7
85
73
765
0.95
0.13
1.4
1.9
—
—
—
0
0
32
296
1.08
0.13
1.1
1.1
—
—
—
0
0
26
283
0.92
0.12
2.2
1.9
15.54
16.77
nmol/l
0.39
26
260
17
152
1.12
0.12
1.8
1.8
—
—
—
0
0
21
229
0.92
0.10
1.8
1.2
—
—
—
0
0
68
709
0.96
0.10
1.4
2.0
—
—
—
0
0
31
290
1.07
0.10
1.9
2.4
7.41
7.43
ph
0.31
12
104
5
44
1.14
0.10
1.0
1.3
101.00
156.11
mmol/l
—
5
38
29
271
1.07
0.09
2.1
1.7
—
—
—
0
0
46
483
0.95
0.09
1.1
1.1
—
—
—
0
0
36
381
0.94
0.09
1.3
1.4
35.55
30.73
u/l
0.30
28
313
5
48
1.04
0.09
1.4
1.1
—
—
—
0
0
326
3308
0.98
0.09
7.6
6.9
24.07
24.59
mmol/l
1.72
309
3155
213
2165
0.98
0.07
1.9
1.9
1.09
2.13
ug/l
1.92
192
1906
51
530
0.96
0.07
1.1
1.2
7.27
7.66
mmol/l
0.37
41
463
51
491
1.04
0.07
2.2
2.7
—
—
—
0
0
117
1196
0.98
0.07
5.7
6.8
104.75
105.01
mmol/l
0.25
107
1075
117
1196
0.98
0.07
5.7
6.8
11.69
11.33
mmol/l
0.60
107
1075
9
103
0.87
0.06
1.2
1.4
—
—
—
0
0
18
193
0.93
0.06
1.3
1.2
—
—
—
0
0
45
434
1.04
0.06
1.6
1.3
—
—
—
0
0
71
729
0.97
0.06
2.2
2.8
—
—
—
0
0
56
543
1.03
0.05
3.9
4.3
—
—
—
0
0
310
3073
1.01
0.04
1.3
1.4
—
—
—
0
0
47
484
0.97
0.04
1.1
1.1
—
—
—
0
0
76
745
1.02
0.04
1.4
1.9
—
—
—
0
0
315
3126
1.01
0.04
2.5
3.1
4.52
5.19
e9/l
0.77
236
2482
108
1096
0.99
0.03
1.9
1.6
—
—
—
0
0
13
121
1.07
0.03
1.0
1.1
—
—
—
0
0
24
230
1.04
0.03
1.4
1.2
1.11
1.23
nmol/l
0.30
17
182
16
151
1.06
0.03
2.3
1.6
—
—
—
0
0
69
678
1.02
0.03
1.8
1.6
0.93
0.84
g/l
0.17
56
517
36
350
1.03
0.03
1.9
2.0
2.53
2.13
ug/l
0.27
26
290
99
1003
0.99
0.03
3.6
3.5
24.04
29.08
mg/l
0.92
63
630
60
589
1.02
0.02
1.4
2.0
—
—
—
0
0
85
838
1.01
0.02
1.3
1.4
—
—
—
0
0
186
1846
1.01
0.02
4.8
3.9
1.51
1.40
mmol/l
0.45
180
1816
44
431
1.02
0.02
1.6
1.3
2.93
2.96
g/l
0.04
31
308
44
431
1.02
0.02
1.6
1.3
6.93
6.84
g/l
0.05
31
307
44
431
1.02
0.02
1.6
1.3
0.33
0.41
g/l
1.00
30
305
10
93
1.08
0.02
1.7
3.1
—
—
—
0
0
33
322
1.02
0.01
2.5
2.6
—
—
—
0
0
76
768
0.99
0.01
1.4
1.9
—
—
—
0
0
29
297
0.98
0.01
1.0
1.1
—
—
—
0
0
85
842
1.01
0.01
1.3
1.3
39.59
39.82
u/l
0.00
70
734
36
367
0.98
0.01
1.7
2.0
1.94
1.48
u/field
0.25
17
131
10
94
1.06
0.01
1.4
2.0
—
—
—
0
0
12
114
1.05
0.00
1.3
1.4
—
—
—
0
0
26
254
1.02
0.00
5.5
6.6
—
—
—
0
0
19
188
1.01
0.00
1.9
1.5
—
—
—
0
0
27
272
0.99
0.00
1.3
1.3
—
—
—
0
0
36
365
0.99
0.00
1.6
1.3
165.14
187.42
pmol/l
0.35
36
365
17
166
1.02
0.00
1.9
2.1
10371.89
19215.73
e6/l
—
9
92
10
97
1.03
0.00
1.5
1.4
—
—
—
0
0
45
447
1.01
0.00
1.1
1.2
—
—
—
0
0
208
2084
1.00
0.00
1.5
1.5
—
—
—
0
0
10
101
0.99
0.00
8.4
6.9
—
—
—
0
0
76
763
1.00
0.00
1.4
1.9
—
—
—
0
0
107
1073
1.00
0.00
3.0
3.5
160.22
793.78
u/ml
1.60
96
988
21
209
1.00
0.00
1.2
1.1
18.44
12.23
iu/ml
—
9
59
26
259
1.00
0.00
1.8
1.4
1.55
1.54
g/l
0.11
26
259
53
529
1.00
0.00
3.5
3.6
60.08
56.91
%
0.53
46
437
0
8
0.00
0.00
0.0
1.1
—
1303.75
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.4
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
1760.00
—
0
7
9
93
0.97
-0.00
1.0
1.3
—
90.17
—
0
18
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
42.11
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
2.2
2.2
—
—
—
0
0
9
97
0.93
-0.00
1.1
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_RETINALDETACHBREAK and mortality.

Females

Parameter HR [95% CI] p-value
H7_RETINALDETACHBREAK 0.994 [0.91, 1.09] 0.901
Birth year 0.996 [0.99, 1.0] 0.284

During the follow-up period (1.1.1998 — 31.12.2019), 2259 out of 12600 females with H7_RETINALDETACHBREAK died.

Males

Parameter HR [95% CI] p-value
H7_RETINALDETACHBREAK 0.965 [0.88, 1.06] 0.442
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 3077 out of 16087 males with H7_RETINALDETACHBREAK died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETINALDETACHBREAK.

N-year risk Females Males
1 0.104% 0.192%
5 0.655% 1.074%
10 1.597% 2.582%
15 3.115% 5.082%
20 5.255% 8.492%

Relationships between endpoints

Index endpoint: H7_RETINALDETACHBREAK – Retinal detachment with retinal break

GWS hits: 6

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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