Ulcer of vagina/vulva

N14_ULCERVAGVUL

anus disease: A non-neoplastic or neoplastic disorder that affects the anal canal or anal margin. Representative examples of non-neoplastic disorders include hemorrhoids and anal ulcer. Representative examples of neoplastic disorders include carcinoma, lymphoma, and melanoma. [database_cross_reference: NCIT:C26695]

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N76.5, N76.6
  • Hospital discharge: ICD-9 6165
  • Cause of death: ICD-10 N76.5, N76.6
  • Cause of death: ICD-9 6165

2 out of 7 registries used, show all original rules.

1005

4. Check minimum number of events

None

1005

5. Include endpoints

None

1005

6. Filter based on genotype QC (FinnGen only)

960

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENINF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5605 5605 -
Only index persons 5168 5168 -
Unadjusted period prevalence (%)
Whole population 0.16 0.16 -
Only index persons 0.19 0.19 -
Median age at first event (years)
Whole population - 46.23 -
Only index persons - 48.21 -

-FinnGen-

Key figures

All Female Male
Number of individuals 960 960 -
Unadjusted period prevalence (%) 0.34 0.34 -
Median age at first event (years) 52.38 52.38 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1005
Matched controls
10050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N76.6
ICD-10 Finland
Ulceration of vulva
777.5
307.7
703
30
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
27.3
307.7
266
131
N76.5
ICD-10 Finland
Ulceration of vagina
387.8
307.7
336
13
ULA02
NOMESCO Finland
Kolposcopy
7.1
185.0
369
759
LEB00
NOMESCO Finland
Biopsy of vagina
16.1
125.5
111
77
D07AD01
ATC
clobetasol; topical
4.4
98.1
333
1023
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
8.3
96.7
136
185
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
4.0
79.7
291
927
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
3.2
69.7
553
2810
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
14.4
56.5
52
38
J02AC01
ATC
fluconazole; systemic
2.6
46.8
597
3624
N76.3
ICD-10 Finland
Subacute and chronic vulvitis
13.7
43.6
41
31
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
6.6
40.6
67
107
N76.2
ICD-10 Finland
Acute vulvitis
16.7
40.2
34
21
N76.0
ICD-10 Finland
Acute vaginitis
3.6
38.6
138
420
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.7
34.5
227
980
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.4
32.0
274
1337
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
31.0
465
2857
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
6.1
30.8
55
95
P01AB01
ATC
metronidazole; oral, rectal
2.1
28.8
484
3080
N76.8
ICD-10 Finland
Other specified inflammation of vagina and vulva
7.4
27.3
40
56
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
10.0
26.9
31
32
LCA06
NOMESCO Finland
Biopsy of endometrium
2.5
26.6
198
898
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
8.1
26.5
36
46
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
5.1
25.8
55
112
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
25.5
345
2003
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.0
25.5
619
4430
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.9
25.4
131
493
J05AB11
ATC
valaciclovir; oral
2.4
24.8
199
932
N94.1
ICD-10 Finland
Dyspareunia
5.7
24.8
47
86
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
24.7
363
2169
E0000UV, ,
ATC
2.0
24.1
504
3398
D07AC01
ATC
betamethasone; topical
2.0
22.6
392
2466
L29.2
ICD-10 Finland
Pruritus vulvae
5.0
22.4
49
102
G01AA10
ATC
clindamycin; vaginal
2.2
21.9
226
1172
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
21.4
212
1081
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
8.6
21.1
27
32
LFC00
NOMESCO Finland
Partial excision of vulva
22.0
20.9
30
14
N77.1*B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
4.8
20.7
48
105
UKC02
NOMESCO Finland
Cystoscopy
2.7
19.7
118
479
A02BC02
ATC
pantoprazole; systemic
1.9
19.4
675
5220
L43.9
ICD-10 Finland
Lichen planus, unspecified
5.3
19.2
39
76
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.2
19.1
178
883
J01DB01
ATC
cefalexin; oral
2.3
18.9
861
7276
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
71.3
18.8
21
*
X15
ICPC
Vaginal symptom/complaint other
2.9
18.2
88
318
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
17.9
265
1557
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
67.9
17.8
20
*
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
2.3
17.4
155
753
N03AX16
ATC
[U] pregabalin
2.0
17.1
238
1366
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
5.8
16.9
31
55
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
16.7
288
1774
J05AB01
ATC
aciclovir; systemic
1.9
16.6
270
1633
N30.0
ICD-10 Finland
Acute cystitis
1.9
16.4
236
1368
J01MA02
ATC
ciprofloxacin; systemic
1.8
16.4
352
2317
H02AB06
ATC
prednisolone; systemic
1.7
16.2
462
3296
N81.1
ICD-10 Finland
Cystocele
2.5
16.2
106
448
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
21.4
16.0
23
11
U07
ICPC
Urine symptom/complaint other
2.6
15.6
96
394
J01EA01
ATC
trimethoprim; systemic
1.8
15.3
342
2269
B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
4.3
15.2
39
93
UJF32
NOMESCO Finland
Coloscopy
1.9
15.1
242
1450
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
15.0
399
2775
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.4
14.9
106
465
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
14.7
120
560
X16
ICPC
Vulval symptom/complaint
4.1
14.6
40
100
N89.8
ICD-10 Finland
Other specified noninflammatory disorders of vagina
5.9
14.0
25
43
M25.5
ICD-10 Finland
Pain in joint
1.7
14.0
355
2428
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
54.1
13.8
16
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
13.8
75
289
R52.9
ICD-10 Finland
Pain, unspecified
2.3
13.7
109
503
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.8
13.5
268
1706
N02AX02
ATC
tramadol; systemic, rectal
1.7
13.5
377
2641
N95.0
ICD-10 Finland
Postmenopausal bleeding
2.2
13.4
119
575
R51.80
ICD-10 Finland
Headache
1.9
13.2
200
1171
N30
ICD-10 Finland
Cystitis
2.1
13.2
128
640
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.8
13.0
66
245
N76.4
ICD-10 Finland
Abscess of vulva
17.0
13.0
20
12
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
3.2
13.0
53
174
M79.6
ICD-10 Finland
Pain in limb
1.6
12.9
440
3233
C05AA08
ATC
fluocortolone; rectal, topical
2.1
12.9
136
703
N06AX11
ATC
mirtazapine; oral
1.7
12.7
355
2478
N03AX12
ATC
[U] gabapentin; oral
1.9
12.7
167
934
U02
ICPC
Urinary frequency/urgency
1.9
12.6
195
1150
E000006, ,
ATC
2.4
12.5
90
397
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.9
12.5
61
222
L43.8
ICD-10 Finland
Other lichen planus
4.4
12.5
31
72
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.3
12.4
100
463
K12.00
ICD-10 Finland
Recurrent oral aphthae
4.9
12.4
27
56
A02BC05
ATC
esomeprazole; systemic
1.6
12.3
397
2868
WX400
NOMESCO Finland
Inhalation anesthesy
2.8
12.2
61
225
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
12.1
151
828
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.5
11.9
23
43
J01CA08
ATC
pivmecillinam; oral
1.6
11.8
571
4532
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
4.8
11.7
26
55
A02BC03
ATC
lansoprazole; oral
1.7
11.6
268
1771
R06.0
ICD-10 Finland
Dyspnoea
1.7
11.5
256
1673
N06AX21
ATC
duloxetine; oral
2.0
11.5
143
782
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
11.5
271
1800
R06AX27
ATC
desloratadine; oral
1.6
11.4
340
2398
J01FF01
ATC
clindamycin; systemic
1.7
11.3
257
1690
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.4
11.1
81
359
X29
ICPC
Genital sympt/compl female other
4.0
11.1
31
79
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
10.9
135
737
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
10.9
201
1245
N81.6
ICD-10 Finland
Rectocele
2.2
10.9
95
455
M54.5
ICD-10 Finland
Low back pain
1.6
10.9
372
2707
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.4
10.8
79
351
G04BD12
ATC
mirabegron; oral
2.1
10.8
108
546
G04BD08
ATC
solifenacin; oral
2.5
10.7
68
283
ZXE00
NOMESCO Finland
One hour or less
1.6
10.7
398
2949
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
2.4
10.7
74
321
M35.2
ICD-10 Finland
Behçet disease
60.7
10.6
12
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.4
10.6
38
115
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
10.6
404
3010
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.5
339
2429
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.1
10.5
97
476
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.9
10.5
48
169
LWW96
NOMESCO Finland
Other reoperation in gynaecological surgery
19.0
10.3
15
8
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.9
10.2
142
806
Z2221
NOMESCO Finland
Medical doctor
1.6
10.1
292
2033
N90.4
ICD-10 Finland
Leukoplakia of vulva
11.4
10.1
18
16
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
10.0
124
676
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
10.0
367
2700
N02BE01
ATC
paracetamol; systemic, rectal
1.9
10.0
887
8014
N30.9
ICD-10 Finland
Cystitis, unspecified
2.2
10.0
81
377
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
9.8
108
565
R52.2
ICD-10 Finland
Other chronic pain
2.9
9.7
46
165
M01AH05
ATC
etoricoxib; oral
1.5
9.7
581
4749
UJH02
NOMESCO Finland
Anoscopy
2.8
9.7
47
171
C51.81
ICD-10 Finland
Squamous cell carcinoma of the vulva
55.5
9.7
11
*
D06BB10
ATC
imiquimod; topical
2.5
9.7
63
266
JAH01
NOMESCO Finland
Laparoscopy
2.7
9.6
52
200
L29.9
ICD-10 Finland
Pruritus, unspecified
3.1
9.6
40
133
LEG12
NOMESCO Finland
Transobturatoric tape
4.4
9.6
24
56
R01AD09
ATC
mometasone; nasal
1.5
9.6
481
3780
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
9.6
402
3043
N39.3
ICD-10 Finland
Stress incontinence
2.1
9.5
97
494
WX320
NOMESCO Finland
Spinalanesthesy
1.6
9.5
235
1572
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
9.5
370
2754
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
9.5
230
1531
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
9.4
77
359
N02BF01
ATC
gabapentin; oral
2.1
9.4
89
440
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
+∞
9.4
9
*
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.7
9.3
29
80
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
9.3
557
4536
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.2
214
1407
K30
ICD-10 Finland
Functional dyspepsia
1.9
9.2
127
719
K60.0
ICD-10 Finland
Acute anal fissure
5.1
9.1
19
38
A01
ICPC
Pain general/multiple sites
2.0
9.1
101
530
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
2.0
9.1
97
502
A07EA02
ATC
hydrocortisone; rectal
3.7
9.0
28
77
XKC03
NOMESCO Finland
Water cystometry
3.2
9.0
36
117
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
8.8
178
1126
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
8.8
149
897
J01FA10
ATC
azithromycin; systemic
1.5
8.8
623
5223
R42
ICD-10 Finland
Dizziness and giddiness
1.6
8.8
217
1448
J01MA12
ATC
levofloxacin; systemic
1.8
8.7
147
883
H02AB04
ATC
methylprednisolone; systemic
1.8
8.7
137
808
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.6
186
1197
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
8.6
207
1370
P06
ICPC
Sleep disturbance
1.8
8.6
125
718
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
8.6
190
1231
J01AA02
ATC
doxycycline; systemic
1.5
8.6
720
6238
LDA10
NOMESCO Finland
Curettage of cervix uteri
2.4
8.6
61
268
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
8.5
220
1484
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
20.2
8.5
12
6
B01AB05
ATC
enoxaparin; parenteral
1.6
8.4
283
2027
U05
ICPC
Urination problems other
2.6
8.4
48
190
N77.1
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
4.5
8.4
20
45
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
+∞
8.3
8
*
G44.2
ICD-10 Finland
Tension-type headache
1.7
8.3
163
1022
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
3.2
8.3
33
107
N77.1*A60.0
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in herpesviral [herpes simplex] infection
10.9
8.3
15
14
U01
ICPC
Dysuria/painful urination
1.9
8.3
111
621
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
8.3
123
711
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
8.3
319
2353
K13.78
ICD-10 Finland
Other change in the oral mucosa
3.5
8.3
28
82
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
8.2
148
906
N05CF01
ATC
zopiclone; oral
1.5
8.2
284
2046
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
8.1
132
784
UJF92
NOMESCO Finland
Capsular endoscopy
3.5
8.1
27
78
Z71.8
ICD-10 Finland
Other specified counselling
1.5
8.1
342
2569
R01AD58
ATC
fluticasone, combinations; nasal
1.6
8.1
265
1885
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
8.0
88
460
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.6
8.0
45
177
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.5
8.0
48
195
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
7.3
8.0
18
25
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
8.0
282
2040
N06AB10
ATC
escitalopram; oral
1.6
8.0
229
1581
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
7.9
331
2478
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.5
7.9
48
196
WX002
NOMESCO Finland
Sedation and analgesia
1.7
7.9
171
1101
S31.4
ICD-10 Finland
Open wound of vagina and vulva
13.2
7.9
13
10
M79.1
ICD-10 Finland
Myalgia
1.7
7.8
164
1047
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
7.8
165
1056
R33
ICD-10 Finland
Retention of urine
2.8
7.8
38
139
A02BC01
ATC
omeprazole; systemic
1.5
7.8
252
1787
C51.9
ICD-10 Finland
Malignant neoplasm: Vulva, unspecified
15.2
7.7
12
8
D07BC01
ATC
betamethasone and antiseptics; topical
1.9
7.7
108
613
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
7.7
129
773
XKD03
NOMESCO Finland
Urethral pressure profilometry
3.3
7.7
29
91
G04CA02
ATC
tamsulosin; oral
3.3
7.7
28
86
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.7
209
1423
R30.0
ICD-10 Finland
Dysuria
2.5
7.6
48
200
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
7.6
116
677
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
7.5
125
747
N75.1
ICD-10 Finland
Abscess of Bartholin gland
10.1
7.5
14
14
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
7.5
110
633
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
7.5
110
633
N06AA09
ATC
amitriptyline; systemic
1.9
7.5
95
522
XKD00
NOMESCO Finland
Uroflowmetry
2.5
7.5
45
183
J02AC02
ATC
itraconazole; systemic
1.7
7.5
165
1066
U13
ICPC
Bladder symptom/complaint other
2.7
7.5
38
142
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
80.7
7.4
8
*
LEE96
NOMESCO Finland
Other repair of vagina
80.7
7.4
8
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.4
7.4
51
222
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.7
7.3
132
808
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
7.3
233
1643
SPAT1263
SPAT
Sampling
1.4
7.3
423
3363
N99.3
ICD-10 Finland
Prolapse of vaginal vault after hysterectomy
3.0
7.3
31
105
N06AB04
ATC
citalopram; systemic
1.6
7.2
202
1382
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
15.9
7.2
11
7
J01MA06
ATC
norfloxacin; oral
1.7
7.2
136
843
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
7.2
185
1242
R06AE07
ATC
cetirizine; oral
1.4
7.2
470
3819
E000001, ,
ATC
1.6
7.2
212
1470
EKA10
NOMESCO Finland
iopsy of buccal mucosa
3.2
7.2
27
85
S29
ICPC
Skin symptom/complaint other
1.6
7.1
187
1262
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.1
7.1
63
305
D01
ICPC
Abdominal pain/cramps general
1.7
7.0
139
873
X14
ICPC
Vaginal discharge
2.6
7.0
38
147
N05AH04
ATC
quetiapine; oral
1.6
7.0
172
1141
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
7.0
7.0
16
23
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
7.0
86
468
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
7.0
89
490
R21
ICPC
Throat symptom/complaint
1.5
7.0
266
1947
K59.0
ICD-10 Finland
Constipation
2.3
7.0
54
247
M01AB05
ATC
diclofenac; systemic, rectal
1.4
6.9
591
5023
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.6
6.9
38
148
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.9
410
3265
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
13.9
6.9
11
8
K60.2
ICD-10 Finland
Anal fissure, unspecified
3.6
6.9
22
62
N05BA04
ATC
oxazepam; oral
1.5
6.9
251
1820
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
6.9
77
406
R12
ICD-10 Finland
Heartburn
1.9
6.9
85
464
K05.1
ICD-10 Finland
Chronic gingivitis
2.0
6.8
79
421
N75.0
ICD-10 Finland
Cyst of Bartholin gland
11.0
6.8
12
11
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.8
239
1720
H92.0
ICD-10 Finland
Otalgia
2.0
6.8
74
387
LEE00
NOMESCO Finland
Suture of vagina
16.8
6.8
10
6
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
6.7
271
2003
M35.7
ICD-10 Finland
Hypermobility syndrome
3.3
6.7
25
78
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
2.3
6.7
48
213
XLA10, ,
NOMESCO Finland
2.2
6.6
57
272
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
6.6
126
782
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
6.6
100
581
WX702
NOMESCO Finland
Supraglottic ventilation device
2.2
6.6
56
266
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
6.6
61
300
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
2.3
6.5
49
221
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.5
171
1151
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
6.5
61
301
L04
ICPC
Chest symptom/complaint
2.0
6.5
73
385
P76
ICPC
Depressive disorder
1.9
6.5
80
436
D07CC01
ATC
betamethasone and antibiotics; topical
1.7
6.5
127
795
L04AX03
ATC
methotrexate; systemic
1.8
6.5
96
555
L02
ICPC
Back symptom/complaint
1.7
6.4
115
702
XQ800
NOMESCO Finland
Prick test
1.8
6.4
90
511
M03BX02
ATC
tizanidine; oral
1.4
6.4
587
5019
N70.9
ICD-10 Finland
Salpingitis and oophoritis, unspecified
70.3
6.4
7
*
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
2.2
6.4
51
236
D06
ICPC
Abdominal pain localized other
1.8
6.4
98
572
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
2.2
6.4
52
243
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
6.4
84
468
C01CA24
ATC
epinephrine; parenteral
1.9
6.4
80
439
P03
ICPC
Feeling depressed
1.7
6.4
126
791
WX704
NOMESCO Finland
Intubation
2.0
6.3
70
368
N81.3
ICD-10 Finland
Complete uterovaginal prolapse
6.0
6.3
16
27
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
6.3
74
397
S21
ICPC
Skin texture symptom/complaint
1.6
6.3
139
898
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.3
415
3354
N75.8
ICD-10 Finland
Other diseases of Bartholin gland
18.1
6.3
9
5
N77.8*M35.2
ICD-10 Finland
Ulceration of vulva in Behçet's disease
+∞
6.3
6
*
61207
ICD-8 Finland
Acute salpingitis and oophoritis, suspecta
+∞
6.3
6
*
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.3
395
3167
C07AA05
ATC
propranolol; systemic
1.5
6.2
222
1599
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
6.2
92
533
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.2
712
6320
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.6
6.2
35
139
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.9
6.1
72
386
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
6.1
32
122
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
12.6
6.1
10
8
K60.1
ICD-10 Finland
Chronic anal fissure
2.9
6.1
27
94
R01AD12
ATC
fluticasone furoate; nasal
1.4
6.1
327
2546
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
6.1
728
6495
XX3DW
NOMESCO Finland
Time consuming IT work
1.8
6.1
89
513
R03AC02
ATC
salbutamol; inhalant
1.4
6.1
553
4707
SPAT1260
SPAT
Consultation of another employee
1.6
6.0
165
1121
R74
ICPC
Upper respiratory infection acute
1.4
6.0
367
2919

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
211
870
2.80
35.13
2.0
1.5
—
—
—
0
0
544
3494
2.21
33.09
2.7
2.0
—
—
—
0
0
81
186
4.65
33.07
1.7
1.8
—
—
—
0
0
462
2966
2.03
26.08
3.8
2.8
—
—
—
0
0
764
5930
2.20
25.01
6.6
4.3
2050.50
3119.19
e6/l
—
8
72
609
4398
1.98
23.66
4.7
3.6
0.00
0.00
estimate
0.50
130
851
604
4367
1.96
23.18
6.1
4.8
0.00
0.00
estimate
0.50
131
865
768
6087
2.11
22.11
6.1
4.2
—
—
—
0
0
375
2354
1.95
21.52
2.7
2.2
55.37
58.87
u/l
0.75
334
2140
363
2277
1.93
20.70
3.6
3.0
37.86
67.24
e6/l
0.73
287
1697
339
2099
1.93
19.96
3.6
2.9
0.21
0.42
e6/l
2.52
261
1557
588
4360
1.84
19.29
4.7
3.5
0.00
0.00
estimate
0.50
134
908
426
2870
1.84
19.06
4.5
3.4
57.31
91.19
e6/l
1.52
303
1849
333
2086
1.89
18.68
3.6
2.8
—
—
—
0
0
759
6144
1.96
18.43
8.1
6.5
73.55
75.21
u/l
0.68
720
5742
766
6225
1.97
18.32
5.2
3.9
11.98
11.44
mm/h
0.47
716
5745
576
4308
1.79
17.71
7.0
5.4
1.99
1.95
e9/l
0.23
517
3848
491
3507
1.78
17.66
4.1
3.3
5.98
5.93
ph
0.16
58
254
483
3438
1.78
17.54
5.7
4.9
1.22
1.22
mmol/l
0.00
444
3121
560
4165
1.78
17.44
7.0
5.5
0.53
0.54
e9/l
0.14
486
3638
560
4170
1.77
17.32
7.0
5.5
0.04
0.04
e9/l
0.07
487
3635
214
1180
2.03
17.28
2.5
2.3
147.62
100.89
ug/g
0.80
174
905
464
3276
1.77
17.23
4.9
4.1
35.84
36.07
g/l
0.41
426
3034
575
4323
1.77
17.12
7.1
5.7
0.18
0.18
e9/l
0.27
516
3825
515
3762
1.76
16.86
7.0
5.6
0.68
0.68
%
0.04
477
3495
187
991
2.09
16.78
2.2
1.8
—
—
—
0
0
529
3898
1.75
16.76
7.7
5.9
—
—
—
0
0
539
3993
1.75
16.76
5.5
5.3
9.40
10.08
umol/l
1.50
503
3758
530
3909
1.75
16.72
6.9
5.5
2.84
2.71
%
0.71
497
3649
547
4071
1.75
16.71
6.9
5.6
29.72
29.16
%
0.61
515
3821
258
1535
1.92
16.65
3.1
2.7
498.02
514.53
mosm/kgh2o
0.58
217
1323
625
4850
1.76
16.31
9.4
8.3
3.90
3.92
e9/l
0.07
560
4266
530
3932
1.74
16.17
7.1
5.8
8.23
8.08
%
0.56
496
3684
949
8518
3.05
15.94
16.7
11.5
19.78
19.98
mg/l
0.07
786
6579
536
4023
1.71
15.39
6.5
5.4
55.79
56.65
%
0.98
504
3768
263
1610
1.86
15.38
2.9
2.4
7.52
9.00
e6/l
0.76
229
1438
208
1180
1.96
15.33
1.5
1.4
594.42
642.76
titre
0.11
43
261
201
1139
1.96
14.82
3.2
2.6
4.94
4.62
e6/l
0.11
119
563
328
2169
1.76
14.73
2.3
2.1
116.25
174.73
u/l
1.17
305
2042
509
3799
1.69
14.65
6.0
5.6
1.22
1.22
mmol/l
0.07
417
3206
345
2339
1.72
14.05
4.1
3.4
7.40
7.40
ph
0.46
77
448
296
1937
1.75
13.60
4.1
3.5
94.84
94.73
%
0.03
283
1872
53
172
3.20
13.22
4.3
3.7
55.85
58.18
%
0.70
53
172
27
53
5.21
13.21
1.3
1.3
—
—
—
0
0
290
1908
1.73
12.98
1.9
1.8
0.75
1.00
mg/l
2.67
219
1424
207
1235
1.85
12.89
3.1
2.4
1.40
1.26
e6/l
0.10
125
653
368
2598
1.66
12.56
3.7
3.2
26.76
44.48
ng/l
0.51
210
1533
23
21
11.18
12.56
2.1
2.2
1.81
2.10
ug/l
—
18
9
51
167
3.16
12.54
4.2
3.4
3.80
4.25
e9/l
0.79
51
167
574
4526
1.63
12.51
4.7
4.0
6.32
6.43
mmol/l
0.61
534
4085
81
343
2.48
12.31
1.4
1.2
—
—
—
0
0
430
3171
1.62
12.25
2.2
1.9
100.95
97.61
pmol/l
0.64
230
1554
297
2007
1.68
11.87
4.6
3.5
—
—
—
0
0
659
5427
1.62
11.59
3.3
2.8
35.55
35.73
u/l
0.02
612
5097
144
788
1.97
11.59
2.1
2.1
371.81
382.84
nmol/l
0.25
133
717
189
1131
1.83
11.56
3.4
3.0
0.82
0.82
mmol/l
0.04
177
1060
211
1307
1.78
11.50
3.3
3.4
52.71
324.27
ng/l
3.04
140
892
928
8446
2.29
11.40
17.3
12.7
139.51
139.57
mmol/l
0.28
914
8183
830
7284
1.80
11.22
5.2
4.4
14.66
14.61
pmol/l
0.20
775
6678
928
8468
2.25
10.96
17.5
12.8
3.90
3.91
mmol/l
0.70
912
8183
258
1721
1.67
10.67
4.3
3.6
—
—
—
0
0
282
1925
1.65
10.66
1.6
1.5
2.14
2.14
g/l
0.02
166
1125
182
1107
1.79
10.47
1.3
1.2
—
—
—
0
0
360
2620
1.58
10.40
3.6
2.8
28.22
27.86
u/l
0.08
335
2493
243
1612
1.67
10.21
1.3
1.3
20.26
30.84
iu/ml
1.50
74
519
487
3838
1.52
9.60
11.6
8.3
0.00
0.00
e9/l
0.12
409
3140
410
3118
1.53
9.53
16.1
12.3
1.16
1.15
inr
0.09
144
978
958
8934
2.55
9.47
12.3
9.1
22.97
22.88
u/l
0.07
933
8595
152
903
1.81
9.41
1.7
1.3
—
—
—
0
0
180
1125
1.73
9.36
2.3
2.2
13.68
13.45
umol/l
0.13
167
1041
231
1548
1.64
9.23
1.4
1.2
6.50
12.12
u/ml
1.16
83
602
210
1375
1.67
9.18
1.8
1.7
1231.65
1192.21
nmol/l
0.23
170
1013
165
1012
1.75
9.16
2.3
2.2
2.40
2.44
g/l
0.43
150
936
95
487
2.05
9.14
1.2
1.2
—
—
—
0
0
143
846
1.80
8.96
2.9
2.6
4.87
5.71
umol/l
0.77
121
705
46
173
2.74
8.91
1.1
1.5
—
—
—
0
0
111
611
1.92
8.72
1.5
1.3
1052.45
222.28
u/ml
0.46
104
561
166
1035
1.72
8.67
2.6
2.1
30.46
29.32
s
1.51
155
1000
329
2428
1.53
8.58
3.9
3.2
—
—
—
0
0
642
5437
1.50
8.46
3.9
3.4
—
—
—
0
0
315
2309
1.53
8.46
1.4
1.3
0.94
1.97
u/ml
1.45
83
592
473
3775
1.48
8.36
2.6
2.3
81.51
77.26
nmol/l
2.32
437
3409
296
2147
1.54
8.32
6.4
6.5
—
—
—
0
0
370
2817
1.50
8.25
3.2
3.2
2.34
2.36
mmol/l
2.17
327
2487
150
925
1.73
8.13
2.6
2.3
23.68
22.29
%
0.40
131
786
137
830
1.75
7.90
1.4
1.3
—
—
—
0
0
507
4132
1.46
7.88
2.9
2.4
—
—
—
0
0
293
2143
1.52
7.85
2.4
2.1
2.89
2.91
mg/l
0.04
258
1808
316
2354
1.50
7.73
5.3
3.8
0.00
0.00
estimate
1.08
127
857
39
146
2.74
7.65
2.8
3.6
3.11
2.73
mmol/l
0.19
22
101
99
550
1.89
7.57
1.3
1.4
23.83
23.28
iu/l
0.05
84
473
42
166
2.60
7.42
2.3
2.4
—
—
—
0
0
47
197
2.45
7.36
1.0
1.5
3.80
3.71
mmol/l
0.16
42
185
103
588
1.84
7.23
3.3
3.1
10.95
10.33
g/l
0.73
92
533
46
193
2.45
7.20
1.2
1.5
1031.26
165.39
e6/l
0.46
31
155
46
193
2.45
7.20
1.1
1.5
25.18
16.03
e6/l
0.18
28
146
530
4411
1.43
7.04
3.6
2.8
72.09
74.21
ug/l
0.19
500
4074
843
7678
1.61
7.04
19.9
14.0
14.44
14.50
%
0.12
836
7526
109
640
1.79
6.98
3.0
3.3
25.45
55.62
u/ml
2.04
99
617
951
8975
2.11
6.84
15.9
10.9
—
—
—
0
0
112
668
1.76
6.80
1.6
1.4
—
—
—
0
0
172
1151
1.60
6.75
1.6
1.5
—
—
—
0
0
894
8291
1.71
6.61
6.3
5.2
1.75
1.98
mu/l
0.88
851
7698
35
135
2.65
6.52
2.5
2.2
16.44
15.94
%
0.32
18
61
92
531
1.81
6.25
2.3
2.7
67.63
66.77
g/l
0.61
85
488
313
2420
1.43
6.04
2.4
2.0
—
—
—
0
0
125
794
1.66
6.04
5.6
3.5
—
—
—
0
0
243
1796
1.47
5.96
1.5
1.5
21.65
22.04
nmol/l
0.14
215
1533
35
142
2.52
5.91
3.7
3.0
—
—
—
0
0
799
7277
1.48
5.79
5.5
4.9
38.45
38.48
mmol/mol
0.03
748
6750
25
86
2.96
5.76
1.2
1.5
—
—
—
0
0
19
55
3.50
5.75
2.1
1.7
42.54
42.72
%
0.01
19
55
247
1861
1.43
5.42
4.7
3.9
1.02
1.02
kg/l
0.07
33
295
15
29
5.23
5.40
1.4
1.4
—
—
—
0
0
83
487
1.77
5.35
1.5
1.6
389.96
302.40
mu/l
0.86
71
424
988
9571
2.91
4.98
25.5
17.4
262.63
263.35
e9/l
0.13
977
9319
44
214
2.10
4.95
1.4
1.4
289.58
312.94
ug/g
0.24
19
121
25
94
2.70
4.94
1.2
1.6
—
—
—
0
0
64
356
1.85
4.93
1.1
1.1
—
—
—
0
0
52
270
1.98
4.91
1.2
1.3
14.18
11.96
u/l
0.35
42
218
97
610
1.65
4.88
2.5
2.4
44.19
25.82
au/ml
0.58
13
47
85
516
1.71
4.88
1.4
1.4
—
—
—
0
0
988
9580
2.85
4.80
25.5
17.4
4.40
4.41
e12/l
0.28
972
9309
987
9567
2.77
4.77
25.7
17.4
39.48
39.29
%
0.72
939
9014
988
9582
2.84
4.76
25.5
17.4
6.65
6.66
e9/l
0.09
973
9307
856
7983
1.49
4.75
4.5
4.0
5.73
5.71
mmol/l
0.10
799
7293
82
498
1.70
4.71
2.9
2.7
96.52
190.89
ng/l
3.80
71
455
68
393
1.78
4.64
2.4
2.3
—
—
—
0
0
57
312
1.88
4.63
1.9
2.6
21.20
20.73
s
0.35
49
277
41
200
2.09
4.60
1.9
2.0
—
—
—
0
0
111
733
1.58
4.59
1.4
1.4
—
—
—
0
0
94
597
1.63
4.56
4.1
3.2
—
—
—
0
0
327
2650
1.35
4.51
2.5
2.1
—
—
—
0
0
221
1682
1.40
4.50
1.7
1.6
33702131.22
28942130.43
pmol/l
0.05
181
1389
148
1046
1.49
4.48
1.3
1.2
—
—
—
0
0
23
88
2.65
4.42
1.5
3.1
—
—
—
0
0
110
733
1.56
4.38
2.4
3.0
1.73
1.82
%
0.50
95
647
113
758
1.55
4.37
2.3
2.1
29.71
35.05
u/l
1.02
95
629
279
2216
1.36
4.37
3.0
3.0
6.47
6.76
mmol/l
0.51
243
1898
101
662
1.58
4.32
3.9
3.0
1.23
1.23
mmol/l
0.00
88
552
87
552
1.63
4.25
2.6
2.3
7.32
5.12
e9/l
0.41
69
464
76
467
1.68
4.20
2.2
1.8
1.33
1.42
g/l
0.24
68
424
78
483
1.67
4.19
2.1
2.3
5.51
5.77
ug/l
0.07
61
420
26
109
2.42
4.17
1.5
1.9
1.58
1.69
mmol/l
0.29
26
109
103
684
1.56
4.17
2.3
2.2
1702.98
6030.53
u/l
2.81
34
291
23
91
2.56
4.15
1.3
1.7
—
—
—
0
0
19
68
2.83
4.13
4.1
3.1
—
—
—
0
0
13
30
4.38
4.13
2.3
1.8
275.71
218.95
e6/l
—
7
19
54
302
1.83
4.13
9.4
8.0
—
—
—
0
0
12
26
4.66
4.06
2.3
3.6
114.00
147.78
umol/l
—
7
18
52
289
1.84
4.06
1.2
1.7
—
11.57
—
0
6
39
197
2.02
4.02
1.3
1.3
88.00
82.22
titre
—
5
18
36
177
2.07
3.99
2.7
4.2
32.69
53.60
mg/l
0.49
24
139
36
177
2.07
3.99
2.7
4.1
27.62
43.60
mg/l
1.90
24
140
232
1817
1.36
3.93
3.3
2.9
943.84
1037.43
ng/l
0.23
193
1508
73
453
1.66
3.90
2.3
2.3
—
—
—
0
0
196
1496
1.39
3.89
3.3
2.6
2.45
2.45
mmol/l
0.04
171
1310
32
154
2.11
3.76
1.3
1.2
6.67
4.92
u/ml
0.14
15
71
258
2071
1.33
3.69
3.8
3.4
—
—
—
0
0
12
31
3.90
3.49
1.7
1.6
78.50
83.87
nmol/24h
0.11
12
31
96
659
1.50
3.37
3.3
3.3
4.35
4.53
pmol/l
1.34
87
590
99
684
1.50
3.37
7.0
6.0
0.94
1.15
mmol/l
0.26
77
547
123
888
1.44
3.35
5.2
4.7
1.05
1.05
mmol/l
0.00
117
805
260
2119
1.31
3.30
1.7
1.6
1.33
1.30
mmol/l
0.21
220
1802
55
332
1.69
3.30
1.6
1.3
—
—
—
0
0
38
207
1.87
3.21
1.2
1.5
0.47
0.38
nmol/l
0.35
29
171
34
179
1.93
3.17
1.2
1.3
—
—
—
0
0
32
166
1.96
3.12
1.5
1.3
217.49
246.33
u/ml
0.28
25
96
238
1931
1.30
3.11
3.1
3.2
1074.80
253.95
mg/l
0.75
134
1154
6
8
7.54
3.06
1.3
1.1
—
—
—
0
0
211
1693
1.31
2.98
1.8
1.7
—
—
—
0
0
30
155
1.96
2.97
1.5
1.4
—
—
—
0
0
16
63
2.56
2.96
7.6
6.1
12.67
11.99
mg/l
0.23
16
58
40
229
1.78
2.91
3.6
2.8
—
—
—
0
0
247
2032
1.29
2.89
3.7
3.7
7.58
7.83
mg/mmol
0.04
139
1196
26
129
2.04
2.88
1.2
1.1
—
—
—
0
0
87
606
1.48
2.87
2.8
3.6
84.48
79.61
ng/l
0.19
74
527
77
524
1.51
2.85
9.2
6.6
—
—
—
0
0
88
616
1.47
2.84
1.2
1.2
—
—
—
0
0
21
97
2.19
2.78
3.4
2.2
—
—
—
0
0
77
527
1.50
2.78
2.6
2.7
70.41
73.32
e9/l
0.26
51
394
18
78
2.33
2.75
2.3
1.3
—
—
—
0
0
47
288
1.66
2.71
1.2
1.2
—
—
—
0
0
49
306
1.63
2.63
2.2
2.2
—
—
—
0
0
46
283
1.66
2.62
1.5
2.2
1.50
1.45
g/l
0.12
37
247
18
80
2.27
2.61
2.0
2.5
—
—
—
0
0
21
100
2.12
2.60
1.2
1.0
—
—
—
0
0
26
135
1.95
2.57
2.3
4.5
—
—
—
0
0
93
672
1.42
2.56
2.3
2.2
0.23
0.22
g/l
0.87
87
630
35
202
1.76
2.51
1.1
1.1
11.60
3.84
u/ml
0.80
18
103
11
37
2.99
2.49
1.4
1.9
—
—
—
0
0
111
833
1.37
2.46
1.2
1.2
194.24
153.81
iu/ml
0.30
38
337
53
344
1.57
2.45
1.8
1.8
—
—
—
0
0
20
96
2.11
2.44
1.2
1.2
—
—
—
0
0
9
27
3.35
2.39
1.1
1.2
—
—
—
0
0
243
2044
1.25
2.33
1.8
1.7
—
—
—
0
0
108
815
1.36
2.32
1.2
1.2
—
—
—
0
0
85
618
1.41
2.28
4.0
3.6
2.38
2.00
mmol/l
0.39
74
511
57
384
1.51
2.26
4.1
4.6
—
—
—
0
0
36
217
1.68
2.25
1.6
2.3
5.69
4.82
umol/l
0.25
27
160
327
2853
1.22
2.20
1.7
1.7
—
—
—
0
0
13
54
2.43
2.20
1.1
1.1
—
—
—
0
0
15
67
2.26
2.18
1.1
1.0
—
—
—
0
0
93
693
1.38
2.17
2.9
3.8
12.01
10.08
ug/l
0.10
68
544
19
94
2.04
2.17
1.2
1.2
—
—
nmol/l
—
0
0
82
599
1.40
2.15
4.9
3.6
0.41
0.70
%
1.08
29
146
16
74
2.18
2.15
1.1
1.0
—
—
—
0
0
16
74
2.18
2.15
1.3
1.1
—
—
—
0
0
59
405
1.49
2.15
1.9
1.8
—
—
—
0
0
11
42
2.64
2.14
1.5
1.2
—
—
—
0
0
142
1134
1.29
2.08
1.7
1.4
—
—
—
0
0
23
124
1.87
2.08
1.3
1.2
—
—
—
0
0
15
69
2.19
2.05
1.0
1.1
0.48
3.67
u/ml
—
5
22
62
435
1.45
2.04
1.7
1.8
—
—
—
0
0
25
140
1.81
2.02
1.2
1.1
15.69
7.40
u/ml
—
8
51
32
193
1.68
2.02
1.1
1.1
0.66
0.64
u/ml
0.03
15
79
216
1821
1.24
2.01
2.2
2.4
305.05
5644.50
umol/l
6.50
190
1594
8
26
3.09
2.01
1.6
1.3
—
—
—
0
0
11
44
2.52
2.01
1.4
1.2
—
—
—
0
0
9
32
2.83
2.00
1.6
2.3
0.14
0.13
e9/l
—
9
32
9
32
2.83
2.00
1.3
1.2
—
—
—
0
0
99
756
1.34
2.00
1.6
1.4
—
—
—
0
0
13
57
2.30
1.98
1.1
1.1
1.07
1.06
ratio
—
7
26
39
249
1.59
1.98
4.1
4.3
—
—
—
0
0
62
438
1.44
1.97
1.8
1.7
—
—
—
0
0
83
618
1.37
1.97
5.1
3.9
0.00
0.09
%
3.56
29
143
7
21
3.35
1.96
1.6
2.0
—
—
—
0
0
7
21
3.35
1.96
1.6
2.1
9.29
4.24
%
—
7
21
232
1978
1.22
1.94
2.6
2.0
—
—
—
0
0
11
45
2.46
1.93
6.1
2.6
—
—
—
0
0
62
441
1.43
1.91
1.9
1.7
—
—
—
0
0
35
220
1.61
1.90
1.2
1.1
4.24
4.11
u/ml
0.01
15
115
7
22
3.20
1.88
2.6
2.9
—
—
—
0
0
7
22
3.20
1.88
1.7
2.0
—
—
—
0
0
20
107
1.89
1.87
1.3
1.3
—
—
—
0
0
50
344
1.48
1.83
5.3
4.2
24.82
24.06
mmol/l
0.94
50
334
30
183
1.66
1.83
1.2
1.0
0.73
1.76
u/ml
1.07
13
91
31
191
1.64
1.83
4.9
5.1
1.50
1.39
mg/l
0.25
31
171
5
12
4.18
1.82
1.8
1.4
—
—
—
0
0
5
12
4.18
1.82
1.0
1.2
—
—
—
0
0
79
592
1.36
1.81
5.3
3.9
0.00
0.82
%
0.57
26
119
38
248
1.55
1.78
4.0
2.3
—
—
—
0
0
85
649
1.34
1.74
5.0
3.8
0.59
1.02
%
1.20
32
174
58
416
1.42
1.73
1.5
1.3
—
—
—
0
0
142
1165
1.25
1.70
1.9
1.9
—
—
—
0
0
60
436
1.40
1.67
1.9
1.8
—
—
—
0
0
12
56
2.16
1.61
1.1
1.2
—
—
—
0
0
22
128
1.73
1.61
3.6
2.0
—
—
—
0
0
26
159
1.65
1.60
1.2
1.0
4.68
5.24
u/ml
—
10
73
833
8029
1.22
1.59
4.2
3.9
1.53
1.58
mmol/l
3.24
782
7451
17
92
1.86
1.56
1.3
1.5
—
—
—
0
0
837
8078
1.22
1.53
4.3
3.9
4.68
4.78
mmol/l
2.32
794
7529
44
309
1.44
1.50
1.5
1.3
—
—
—
0
0
15
79
1.91
1.50
1.2
1.2
0.04
1.40
u/ml
—
8
38
18
101
1.80
1.49
3.8
4.0
49.20
59.20
u/ml
—
5
25
55
404
1.38
1.47
2.2
1.8
—
—
—
0
0
36
244
1.49
1.46
1.4
1.3
9.10
2.36
u/ml
—
5
28
53
388
1.39
1.44
3.3
2.9
125.36
127.44
g/l
0.33
53
378
14
73
1.93
1.44
1.4
1.9
28.86
31.16
pg
0.79
14
73
6
22
2.74
1.43
1.0
1.1
—
120.71
—
0
7
7
29
2.42
1.39
1.3
1.4
—
—
—
0
0
24
150
1.61
1.39
2.4
2.1
128.21
128.38
g/l
0.01
19
116
35
239
1.48
1.38
1.1
1.2
—
—
—
0
0
76
593
1.30
1.38
3.0
2.9
—
—
—
0
0
9
41
2.21
1.37
3.2
3.0
423.00
1198.73
u/ml
—
9
41
9
42
2.15
1.34
1.0
1.0
771.78
712.70
ng/l
—
9
27
16
90
1.79
1.33
1.6
2.0
—
—
—
0
0
22
136
1.63
1.33
1.1
1.0
—
—
—
0
0
19
113
1.69
1.32
1.2
1.3
—
—
—
0
0
9
43
2.10
1.30
4.7
3.6
—
—
—
0
0
30
203
1.49
1.26
1.4
1.2
25.90
40.32
u/ml
—
6
24
21
131
1.62
1.24
1.7
1.7
—
—
—
0
0
21
132
1.60
1.21
1.2
1.2
—
—
—
0
0
41
298
1.39
1.20
1.0
1.1
—
—
—
0
0
846
8221
1.18
1.17
4.9
4.3
2.73
2.81
mmol/l
2.06
797
7625
14
79
1.78
1.17
1.6
1.8
46.11
59.91
%
—
9
47
5
20
2.51
1.15
1.6
1.1
7.18
6.92
nmol/l
—
5
20
7
30
2.34
1.12
1.3
1.6
159.29
147.08
mmol/24h
—
7
30
7
30
2.34
1.12
1.4
1.0
—
—
—
0
0
7
32
2.20
1.08
1.0
1.2
—
—
—
0
0
45
340
1.34
1.06
1.8
1.6
—
—
—
0
0
793
7686
1.15
1.05
3.8
3.5
1.25
1.20
mmol/l
1.66
736
7085
9
46
1.97
1.03
1.1
1.5
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
17
106
1.61
1.03
1.4
1.6
—
—
—
0
0
10
53
1.90
1.01
5.8
6.3
—
—
—
0
0
10
53
1.90
1.01
1.6
1.3
67.00
69.89
umol/l
—
10
53
12
68
1.77
1.00
1.6
1.5
—
—
—
0
0
58
459
1.28
1.00
1.6
1.5
—
—
—
0
0
23
156
1.49
0.99
1.0
1.1
—
—
—
0
0
23
156
1.49
0.99
1.0
1.1
—
—
—
0
0
24
165
1.47
0.97
1.0
1.1
—
—
—
0
0
12
69
1.75
0.96
1.4
1.1
—
—
—
0
0
47
364
1.31
0.96
3.9
3.6
7.42
7.41
ph
0.67
15
51
16
101
1.59
0.94
5.7
3.1
63.14
60.47
%
0.19
16
101
22
150
1.48
0.93
1.6
1.8
4656.87
17233.63
e6/l
1.62
15
105
55
438
1.27
0.92
1.5
1.3
191.13
239.84
miu/ml
0.58
28
219
21
143
1.48
0.90
1.1
1.2
—
—
—
0
0
6
29
2.08
0.89
1.0
1.1
—
—
—
0
0
55
445
1.25
0.82
1.5
1.4
—
—
—
0
0
10
58
1.73
0.80
1.1
1.2
—
195.71
—
0
14
10
58
1.73
0.80
4.0
3.8
—
—
—
0
0
38
295
1.30
0.79
2.3
2.8
25.19
25.37
mmol/l
0.12
38
285
55
448
1.24
0.79
1.5
1.5
—
—
—
0
0
5
99
0.50
0.78
3.0
2.2
—
—
—
0
0
10
59
1.70
0.76
1.0
1.1
—
—
—
0
0
7
38
1.85
0.73
1.3
1.6
—
—
—
0
0
5
25
2.00
0.72
1.6
1.7
—
—
—
0
0
5
26
1.93
0.70
1.2
1.3
—
—
—
0
0
17
119
1.44
0.67
1.8
1.8
—
—
—
0
0
5
28
1.79
0.66
1.6
1.5
161.40
142.71
nmol/l
—
5
28
20
145
1.39
0.66
1.2
1.1
2.36
2.50
u/ml
—
9
71
19
138
1.38
0.62
1.6
1.5
—
—
—
0
0
19
138
1.38
0.62
3.2
2.4
48.95
83.90
ug/min
0.27
13
85
10
63
1.59
0.62
1.8
1.6
—
—
—
0
0
11
72
1.53
0.59
1.2
1.2
—
—
—
0
0
14
97
1.45
0.59
1.2
1.3
—
—
—
0
0
8
53
1.51
0.58
1.0
1.0
283.25
311.75
mg/l
—
8
44
0
23
0.00
0.58
0.0
14.3
—
—
—
0
0
6
37
1.63
0.55
1.0
1.2
105.83
180.13
iu/ml
—
6
37
46
546
0.83
0.55
1.3
1.4
—
—
—
0
0
9
64
1.41
0.51
5.8
2.3
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
—
—
—
0
0
7
46
1.53
0.48
4.3
4.6
8.87
10.63
%
—
7
46
7
46
1.53
0.48
2.9
2.6
39257.14
41354.46
ug/l
—
7
46
7
47
1.49
0.47
1.4
1.4
15.90
14.03
pmol/l
—
7
38
13
94
1.39
0.46
1.1
1.1
—
—
—
0
0
5
83
0.60
0.45
1.6
2.1
—
—
—
0
0
50
432
1.17
0.45
4.1
3.3
—
—
—
0
0
19
148
1.29
0.43
1.9
1.5
—
—
—
0
0
29
240
1.21
0.41
8.2
8.5
—
—
—
0
0
5
33
1.52
0.41
1.6
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
50.50
—
0
6
8
59
1.36
0.41
1.8
1.9
—
—
—
0
0
8
59
1.36
0.41
1.1
1.5
0.94
0.98
g/l
—
8
59
0
18
0.00
0.40
0.0
1.1
—
39.67
—
0
9
13
171
0.76
0.39
4.9
3.2
29.43
25.88
mg/l
—
7
100
17
133
1.28
0.38
3.1
3.5
0.67
0.80
nmol/l
—
9
105
9
66
1.37
0.38
3.9
1.6
6.31
6.70
mmol/l
—
9
48
35
299
1.18
0.37
1.9
2.0
4.20
4.65
iu/l
0.16
13
117
5
37
1.35
0.37
2.2
2.1
9.48
10.22
mmol/l
—
5
37
5
37
1.35
0.37
1.0
1.0
—
—
—
0
0
18
143
1.26
0.37
1.5
1.2
—
—
—
0
0
24
198
1.22
0.36
4.6
4.6
—
—
—
0
0
66
593
1.12
0.36
1.9
1.7
—
—
—
0
0
12
157
0.76
0.36
1.3
1.7
7.40
7.58
mmol/l
0.13
12
151
14
108
1.30
0.35
2.4
2.7
—
—
—
0
0
6
43
1.40
0.35
2.0
3.2
—
—
—
0
0
14
109
1.29
0.33
1.1
1.1
—
—
—
0
0
7
56
1.25
0.29
1.0
1.4
—
—
—
0
0
7
57
1.23
0.29
1.7
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
1.32
—
0
11
0
10
0.00
0.21
0.0
5.5
—
—
—
0
0
6
49
1.23
0.20
1.2
1.4
1.53
1.65
g/l
—
6
49
6
53
1.13
0.18
1.2
1.3
—
—
—
0
0
16
138
1.16
0.17
5.8
3.2
—
—
—
0
0
12
104
1.16
0.12
3.7
3.5
18.57
56.73
u/ml
1.46
12
104
10
85
1.18
0.12
1.1
1.1
1.53
1.47
g/l
—
10
75
5
45
1.11
0.10
3.6
2.4
43.80
47.28
%
—
5
27
28
263
1.07
0.08
3.0
2.7
0.15
0.32
g/l
1.36
12
92
24
256
0.94
0.08
4.3
4.1
—
—
—
0
0
73
724
1.01
0.00
3.6
3.8
—
—
—
0
0
10
98
1.02
0.00
3.0
2.3
3.39
47.34
u/ml
—
10
98
84
838
1.00
0.00
1.2
1.3
—
—
—
0
0
290
2898
1.00
0.00
2.9
2.5
—
—
—
0
0
14
135
1.04
0.00
2.9
2.1
13.46
13.10
%
0.49
14
135
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
345.60
—
0
5
9
92
0.98
-0.00
1.2
1.4
46.87
32.91
nmol/l
—
9
79
0
6
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
2.90
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_ULCERVAGVUL and mortality.

Females

Parameter HR [95% CI] p-value
N14_ULCERVAGVUL 1.353 [1.16, 1.58] < 0.001
Birth year 0.99 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 484 out of 4215 females with N14_ULCERVAGVUL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_ULCERVAGVUL.

N-year risk Females Males
1 0.134% No data
5 0.701% No data
10 1.616% No data
15 3.088% No data
20 5.684% No data

Relationships between endpoints

Index endpoint: N14_ULCERVAGVUL – Ulcer of vagina/vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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