Varicella [chickenpox]

AB1_VARICELLA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B01
  • Hospital discharge: ICD-9 05[2]
  • Hospital discharge: ICD-8 05[2]
  • Cause of death: ICD-10 B01
  • Cause of death: ICD-9 05[2]
  • Cause of death: ICD-8 05[2]

2 out of 7 registries used, show all original rules.

1875

4. Check minimum number of events

None

1875

5. Include endpoints

None

1875

6. Filter based on genotype QC (FinnGen only)

1875

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_SKIN_MUCOUS_MEMBRANE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24317 7662 16552
Only index persons 20463 6106 14357
Unadjusted period prevalence (%)
Whole population 0.38 0.22 0.46
Only index persons 0.45 0.22 0.55
Median age at first event (years)
Whole population 15.07 5.26 19.52
Only index persons 15.83 6.61 19.75

-FinnGen-

Key figures

All Female Male
Number of individuals 1875 612 1263
Unadjusted period prevalence (%) 0.44 0.21 0.56
Median age at first event (years) 17.14 10.85 20.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1714
Matched controls
17140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B01.9
ICD-10 Finland
Varicella without complication
494.6
323.0
464
13
05209
ICD-8 Finland
Chickenpox, Unspecified
+∞
323.0
575
*
0529X
ICD-9 Finland
Chickenpox, Varicella without mention of complication
+∞
247.0
231
*
05200
ICD-8 Finland
Chickenpox, Cum meningoencephalitide
+∞
127.7
121
*
B01.8
ICD-10 Finland
Varicella with other complications
782.1
76.9
75
*
05201
ICD-8 Finland
Chickenpox, Cum complicatione alia
+∞
52.4
50
*
05207
ICD-8 Finland
Chickenpox, Suspectae
+∞
50.2
48
*
J05AB01
ATC
aciclovir; systemic
2.6
41.1
355
1577
0528X
ICD-9 Finland
Chickenpox, With unspecified complication
+∞
37.6
36
*
G05.1*B01.1
ICD-10 Finland
Varicella encephalitis
+∞
34.5
33
*
J05AB11
ATC
valaciclovir; oral
2.7
29.3
212
837
0527A
ICD-9 Finland
Chickenpox, With other specified complications
+∞
27.1
26
*
127
Kela drug reimbursment
Transplant complication
7.0
24.7
62
92
H02AB09
ATC
hydrocortisone; systemic
4.9
22.8
76
161
G02.0*B01.0
ICD-10 Finland
Varicella meningitis
+∞
20.9
20
*
L04AA01
ATC
[U] ciclosporin; systemic
8.0
20.8
47
60
L04AD01
ATC
ciclosporin; systemic
5.3
20.1
62
121
B02.9
ICD-10 Finland
Zoster without complication
5.0
19.4
63
130
R50.9
ICD-10 Finland
Fever, unspecified
2.1
18.8
248
1306
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.7
16.0
71
199
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.3
15.8
82
260
Z94.0
ICD-10 Finland
Kidney transplant status
6.1
15.2
41
69
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
45.4
15.1
18
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
9.0
15.0
31
35
L04AX01
ATC
azathioprine; systemic
2.9
14.7
90
321
05699
ICD-8 Finland
Rubella, Non definita
+∞
14.6
14
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.8
14.5
48
103
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
14.3
283
1720
L04AA06
ATC
mycophenolic acid; systemic
4.6
14.1
48
106
A11CC03
ATC
alfacalcidol; systemic
4.7
14.0
47
102
B07.9
ICD-10 Finland
Verruca simplex
4.1
13.7
53
133
B01AF
ICD-10 Finland
NA
+∞
13.6
13
*
ZX120
NOMESCO Finland
Intravenous
2.2
13.5
136
638
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
13.3
555
4097
XW000
NOMESCO Finland
Bone marrow biopsy
3.3
13.2
66
205
B03XA01
ATC
erythropoietin; parenteral
9.1
12.7
26
29
J17.1*B01.2
ICD-10 Finland
Varicella pneumonia
+∞
12.5
12
*
05697
ICD-8 Finland
Rubella, Suspecta
+∞
12.5
12
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
14.8
11.8
19
13
BE00A
NOMESCO Finland
NA
65.4
11.6
13
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
11.6
50
139
B01.0
ICD-10 Finland
Varicella meningitis
+∞
11.5
11
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
11.4
235
1439
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
11.3
104
469
H02AB06
ATC
prednisolone; systemic
1.5
11.3
614
4760
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
11.2
275
1772
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
7.1
11.0
26
37
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.2
11.0
41
100
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
21.6
10.7
15
7
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.0
10.6
41
104
H02AB04
ATC
methylprednisolone; systemic
1.8
10.5
174
993
602
Kela drug reimbursment
Children's severe malnutrition
5.9
10.4
28
48
0520B
ICD-9 Finland
Chickenpox, Postvaricella encephalitis[VARICELLA CUM PNEUMONITIDE]
+∞
10.4
10
*
C03CA01
ATC
furosemide; systemic
1.7
10.2
208
1267
J01DB01
ATC
cefalexin; oral
1.4
10.0
1286
11574
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
4.9
9.9
31
64
Z85.6
ICD-10 Finland
Personal history of leukaemia
26.2
9.8
13
5
TAB00
NOMESCO Finland
Lumbar puncture
2.5
9.7
75
308
137
Kela drug reimbursment
Uraemia requiring dialysis
6.4
9.6
24
38
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
9.4
138
755
05299
ICD-8 Finland
NA
+∞
9.4
9
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.6
9.4
41
117
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
9.3
73
302
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
6.9
9.3
22
32
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
9.3
194
1192
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
9.2
211
1329
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.1
258
1721
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
5.9
9.1
24
41
A04AA01
ATC
ondansetron; systemic, rectal
2.3
9.0
83
375
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
9.0
196
1217
B05DA
ATC
Isotonic solutions
6.5
9.0
22
34
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
8.8
101
504
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
8.6
81
371
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
8.6
122
660
L03AA02
ATC
filgrastim; parenteral
3.3
8.6
42
131
J02AC01
ATC
fluconazole; systemic
1.4
8.6
427
3217
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
8.6
63
255
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.0
8.5
26
53
J01DA01
ATC
[U] cefalexin; systemic
1.3
8.4
884
7559
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
1.7
8.4
184
1146
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.0
8.2
25
51
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.7
8.1
53
201
Z94.4
ICD-10 Finland
Liver transplant status
10.1
8.0
15
15
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.2
8.0
39
122
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
7.8
275
1925
H26.2
ICD-10 Finland
Complicated cataract
4.5
7.8
26
59
C90.0
ICD-10 Finland
Multiple myeloma
5.9
7.7
20
34
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.7
7.7
31
84
A05AA02
ATC
ursodeoxycholic acid; oral
3.7
7.7
31
84
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.7
265
1851
H26.3
ICD-10 Finland
Drug-induced cataract
8.1
7.6
16
20
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
7.6
240
1643
TK800
NOMESCO Finland
Hemodialysis
3.2
7.5
37
117
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.1
7.5
27
66
R11
ICD-10 Finland
Nausea and vomiting
1.9
7.4
105
569
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.4
398
3033
B05DB
ATC
Hypertonic solutions
6.0
7.4
19
32
K06.18
ICD-10 Finland
Another gingival hyperplasia
8.4
7.3
15
18
05599
ICD-8 Finland
Measles, Non definita
+∞
7.3
7
*
XF602
NOMESCO Finland
Bloodpressure monitoring
4.6
7.2
23
50
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.7
7.2
155
962
Z99.2
ICD-10 Finland
Dependence on renal dialysis
30.1
7.1
9
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
7.1
208
1394
E0000UV
ATC
NA
1.4
7.1
529
4256
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
7.1
96
513
153
Kela drug reimbursment
Lenalidomid
8.8
7.0
14
16
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.3
7.0
32
97
WW200
NOMESCO Finland
Immunization
2.5
7.0
50
202
J01FF01
ATC
clindamycin; systemic
1.4
6.9
353
2662
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.6
6.9
29
82
A41.9
ICD-10 Finland
Sepsis, unspecified
2.6
6.9
46
179
B03XA02
ATC
darbepoetin alfa; parenteral
4.0
6.8
25
63
5AB01
NOMESCO Finland
NA
16.8
6.7
10
6
A07AA02
ATC
nystatin; oral
2.2
6.7
62
282
N05BA09
ATC
clobazam; oral
4.4
6.7
22
50
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
6.6
129
778
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
6.4
6.6
16
25
L04AX04
ATC
lenalidomide; oral
8.7
6.6
13
15
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.7
6.5
142
884
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.5
279
2034
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
5.0
6.5
19
38
Z49.2
ICD-10 Finland
Other dialysis
5.7
6.5
17
30
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
6.4
97
541
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
6.4
70
347
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
8.2
6.3
13
16
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
8.2
6.3
13
16
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
6.3
237
1682
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
6.3
92
505
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.0
6.3
80
418
Z94.1
ICD-10 Finland
Heart transplant status
11.1
6.3
11
10
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
18.1
6.3
9
5
B01.1
ICD-10 Finland
Varicella encephalitis
+∞
6.3
6
*
7101
FHL
Needle biopsy in the operating room
+∞
6.3
6
*
0520A
ICD-9 Finland
Chickenpox, Postvaricella encephalitis[ENCEPHALITIS POST VARICELLAM]
+∞
6.3
6
*
A12AA04
ATC
calcium carbonate; oral
3.5
6.2
27
79
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
3.9
6.2
23
59
K03.66
ICD-10 Finland
Tooth plaque
1.8
6.1
105
609
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.1
6.1
61
291
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
3.0
6.0
31
103
ZX121
NOMESCO Finland
Central venous catheter
6.7
6.0
14
21
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.0
6.0
69
347

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
317
1808
1.91
22.06
11.8
7.7
1.1
1.1
mmol/l
0.36
308
1717
45
88
5.21
21.98
37.3
27.0
95.8
136.7
ug/l
3.14
40
66
25
28
9.04
20.33
2.0
2.1
—
—
—
0
0
712
5335
1.54
17.13
7.0
5.6
36.2
36.7
g/l
1.40
675
5023
278
1681
1.77
15.66
2.0
1.7
—
—
—
0
0
333
2119
1.69
15.62
7.3
4.7
0.8
0.8
mmol/l
2.09
315
2013
28
53
5.35
14.20
3.0
2.9
—
—
—
0
0
941
7666
1.46
14.08
10.3
6.4
2.0
2.0
e9/l
0.82
856
6826
913
7399
1.46
14.02
10.3
6.4
0.0
0.0
e9/l
0.03
818
6451
1011
8354
1.46
14.01
13.8
9.4
3.9
4.0
e9/l
0.98
905
7291
910
7384
1.45
13.80
10.3
6.4
0.6
0.6
e9/l
0.31
818
6439
838
6720
1.45
13.40
10.9
6.7
0.7
0.7
%
0.00
791
6358
40
107
3.80
13.28
32.7
36.8
6.5
7.5
ug/l
1.62
31
98
933
7646
1.44
13.19
11.0
6.8
0.2
0.2
e9/l
0.17
848
6780
461
3299
1.53
13.01
5.9
4.3
—
—
—
0
0
862
6976
1.44
12.97
11.1
6.9
8.7
8.6
%
0.65
818
6626
856
6925
1.43
12.87
10.7
6.6
3.0
2.9
%
0.29
805
6540
672
5209
1.45
12.68
3.1
2.3
71.7
71.6
nmol/l
0.00
622
4839
889
7261
1.43
12.58
10.7
6.5
29.9
29.5
%
0.56
840
6869
877
7155
1.42
12.44
10.1
6.4
55.0
55.8
%
1.21
829
6796
27
56
4.88
12.39
1.4
1.4
—
—
—
0
0
161
886
1.89
12.24
4.3
3.3
71.7
72.6
e9/l
0.11
123
662
147
786
1.94
12.18
8.0
4.9
94.6
82.6
ng/l
0.87
142
717
52
177
2.99
11.88
2.4
2.8
1.2
1.2
e9/l
0.14
32
99
696
5487
1.43
11.76
12.6
7.1
1.2
1.2
mmol/l
0.61
651
5061
192
1131
1.78
11.72
5.6
4.7
0.6
0.9
%
1.58
61
317
45
143
3.20
11.55
2.4
2.3
11.5
12.7
%
0.30
26
83
756
6064
1.41
11.52
12.3
7.6
1.2
1.2
mmol/l
0.77
640
5203
183
1070
1.79
11.45
5.4
4.8
0.1
0.1
%
1.39
57
293
203
1226
1.74
11.36
4.5
2.5
9.9
10.4
g/l
0.70
179
1127
632
4922
1.43
11.32
10.8
6.6
—
—
—
0
0
205
1246
1.72
11.21
6.7
3.4
1.8
1.7
%
0.17
189
1144
488
3628
1.47
11.18
11.0
7.2
—
—
—
0
0
970
8146
1.40
11.18
7.6
5.1
6.7
6.7
mmol/l
0.04
917
7561
466
3438
1.47
11.09
8.7
4.2
7.4
7.4
ph
0.20
102
685
40
122
3.33
10.97
1.6
2.0
—
—
—
0
0
175
1024
1.78
10.92
5.3
4.7
0.1
0.4
%
0.39
46
246
374
2669
1.50
10.43
4.2
2.6
5.0
5.2
e6/l
0.08
336
2339
30
78
3.89
10.40
2.1
2.5
161.7
237.0
e6/l
0.75
18
47
74
323
2.34
10.37
1.5
1.9
—
—
—
0
0
288
1962
1.55
9.94
4.2
2.5
13.9
14.5
umol/l
0.70
274
1844
209
1321
1.66
9.85
9.9
5.3
1.2
1.8
mmol/l
1.71
179
1070
146
836
1.81
9.80
11.3
5.9
23.4
24.0
mmol/l
1.62
136
792
353
2520
1.49
9.77
4.3
2.6
561.5
583.6
mosm/kgh2o
0.98
322
2165
209
1324
1.65
9.76
9.9
5.3
5.8
5.9
kpa
0.61
203
1292
802
6624
1.37
9.75
14.0
9.2
0.0
0.0
e9/l
0.54
683
5429
214
1366
1.64
9.70
9.8
5.2
—
7.4
—
0
9
816
6763
1.37
9.68
9.1
6.4
12.2
11.9
umol/l
0.20
778
6422
199
1249
1.66
9.64
16.9
10.9
—
—
—
0
0
36
112
3.26
9.60
2.7
2.9
32.2
39.1
%
—
6
31
172
1041
1.72
9.54
11.8
9.9
24.4
24.9
mmol/l
0.91
172
1036
253
1690
1.57
9.50
4.5
2.6
23.9
24.5
%
0.28
224
1501
183
1128
1.69
9.49
8.9
4.7
4.9
4.8
kpa
0.25
178
1100
70
312
2.29
9.38
4.7
4.0
56.5
55.2
%
0.40
70
312
172
1053
1.70
9.15
4.8
4.3
0.2
0.6
%
4.49
44
236
546
4289
1.39
8.86
4.1
3.3
8.6
8.9
mmol/l
0.65
479
3736
480
3690
1.40
8.85
6.9
4.3
91.8
91.6
%
0.07
471
3611
67
301
2.27
8.83
4.0
3.7
3.7
4.0
e9/l
0.63
67
301
44
162
2.76
8.80
2.2
1.8
—
—
—
0
0
500
3887
1.39
8.60
3.7
3.3
2.3
2.4
mmol/l
0.75
455
3515
45
170
2.69
8.57
1.9
1.7
—
—
—
0
0
45
170
2.69
8.57
1.9
1.7
—
—
—
0
0
45
170
2.69
8.57
1.9
1.7
—
—
—
0
0
45
170
2.69
8.57
1.9
1.7
—
—
—
0
0
303
2151
1.49
8.55
1.9
1.7
—
—
—
0
0
195
1259
1.61
8.43
3.3
2.8
0.2
0.2
g/l
0.20
177
1186
212
1400
1.58
8.34
1.7
1.5
—
—
—
0
0
1187
10550
1.34
8.30
10.8
7.1
82.3
78.8
u/l
1.33
1141
10022
39
139
2.84
8.29
2.1
3.1
0.2
0.2
e9/l
0.13
30
117
129
749
1.78
8.28
1.8
1.5
4.7
6.4
u/l
4.05
108
593
609
4916
1.35
8.20
7.7
7.1
1.1
1.2
inr
0.80
199
1467
467
3615
1.39
8.18
5.2
3.0
0.3
0.4
e6/l
1.06
374
2689
61
273
2.28
8.13
1.3
1.1
—
—
—
0
0
43
164
2.66
8.06
2.5
2.7
641.2
667.1
e6/l
0.06
11
57
43
165
2.64
7.97
1.5
2.1
—
—
—
0
0
39
143
2.76
7.89
2.1
3.0
605.6
559.5
e6/l
0.13
30
118
289
2067
1.47
7.82
3.2
2.7
29.8
29.7
s
0.14
283
2009
484
3795
1.37
7.78
3.9
2.5
840.6
3648.3
umol/l
3.51
441
3452
519
4116
1.36
7.76
3.6
2.4
—
—
—
0
0
154
957
1.66
7.75
1.7
1.4
—
—
—
0
0
72
356
2.06
7.51
1.5
1.9
62.5
6.6
e6/l
1.32
57
277
136
833
1.68
7.24
5.3
2.5
65.8
67.1
g/l
1.02
127
786
88
475
1.89
7.17
8.2
5.4
9.4
9.2
kpa
0.41
80
444
71
356
2.03
7.15
1.5
1.9
1504.5
747.0
e6/l
0.29
59
289
292
2127
1.44
7.15
2.4
2.3
13.4
13.8
nmol/l
0.39
272
1948
423
3300
1.36
6.92
1.9
1.5
2.1
2.4
g/l
2.33
275
2084
392
3022
1.38
6.91
2.7
2.2
2.8
2.8
mg/l
0.06
346
2633
257
1839
1.46
6.91
4.4
2.5
2.3
2.4
g/l
1.19
243
1723
458
3619
1.35
6.90
4.2
3.3
451.9
428.5
mg/l
0.04
311
2517
34
126
2.73
6.78
1.6
1.5
—
—
—
0
0
26
83
3.16
6.72
3.8
3.3
1139.8
705.7
u/ml
0.67
26
83
265
1923
1.44
6.61
2.2
2.2
—
—
—
0
0
27
90
3.03
6.51
5.1
2.0
—
—
—
0
0
492
3961
1.33
6.48
5.4
3.1
61.7
95.3
e6/l
0.43
402
3027
73
387
1.92
6.32
1.9
1.6
121.1
114.8
u/ml
—
9
69
40
167
2.43
6.30
1.7
2.5
—
—
—
0
0
75
406
1.88
6.10
1.9
1.6
—
—
—
0
0
16
39
4.13
6.09
1.7
1.7
—
—
—
0
0
469
3792
1.32
5.92
4.9
4.1
12.3
10.1
mg/mmol
0.46
323
2634
440
3526
1.32
5.91
6.7
4.5
—
—
—
0
0
69
369
1.90
5.84
3.7
2.9
—
—
—
0
0
152
1011
1.55
5.81
6.1
4.3
5.1
5.1
kpa
0.79
138
946
1146
10374
1.27
5.78
5.4
3.7
9.8
9.0
mm/h
1.15
1084
9754
547
4528
1.29
5.77
2.0
1.8
93.9
96.0
pmol/l
0.56
315
2555
145
961
1.55
5.64
3.3
1.7
1.3
1.3
g/l
0.01
132
893
150
1002
1.54
5.63
6.1
4.4
7.4
7.4
ph
0.12
22
101
446
3606
1.31
5.59
5.3
2.9
—
—
—
0
0
20
61
3.30
5.58
1.6
1.6
—
—
—
0
0
188
1321
1.47
5.54
2.9
2.7
35.0
76.7
u/l
0.62
171
1162
170
1171
1.50
5.53
14.1
9.6
1.4
1.4
mmol/l
0.05
164
1122
236
1734
1.41
5.48
1.8
1.6
1138.6
1126.7
nmol/l
0.07
197
1361
149
1001
1.53
5.46
2.3
2.3
11.6
19.7
au/ml
—
8
68
83
482
1.76
5.42
2.9
2.1
1.4
1.4
g/l
0.19
74
415
25
89
2.83
5.41
5.4
3.1
—
—
—
0
0
29
112
2.61
5.39
5.3
3.0
—
—
—
0
0
58
301
1.96
5.38
5.0
4.7
2.0
2.4
mmol/l
0.74
41
190
104
644
1.65
5.37
5.9
2.0
—
—
—
0
0
84
494
1.73
5.26
1.4
1.1
—
—
—
0
0
712
6143
1.26
5.25
4.0
2.8
156.8
128.7
ug/l
0.65
667
5812
16
44
3.66
5.20
3.6
1.8
—
—
—
0
0
267
2022
1.37
5.18
1.5
1.3
562.3
445.6
titre
0.36
52
350
32
133
2.43
5.14
2.1
1.4
0.9
1.0
g/l
2.02
32
133
191
1367
1.44
5.12
2.7
2.3
354.2
364.6
nmol/l
0.33
183
1287
411
3324
1.30
5.09
3.5
3.1
—
—
—
0
0
137
919
1.53
5.07
1.2
1.3
40.6
53.1
au/ml
—
5
40
39
179
2.20
5.02
3.1
1.6
—
—
—
0
0
554
4662
1.27
5.01
6.0
3.5
58.8
65.7
e6/l
0.12
424
3256
502
4178
1.28
4.96
3.1
2.7
59.2
59.1
u/l
0.01
471
3923
69
390
1.80
4.96
1.3
1.3
—
—
—
0
0
109
698
1.60
4.94
1.7
1.5
13.9
19.4
iu/l
1.36
85
557
358
2853
1.31
4.93
4.3
3.1
1093.6
1001.1
ng/l
0.18
289
2328
463
3819
1.28
4.91
2.4
2.2
235.3
270.8
u/l
0.25
444
3636
41
194
2.14
4.90
6.0
4.0
0.6
1.2
%
2.06
35
163
271
2078
1.36
4.85
4.4
2.8
2.5
1.6
e6/l
0.61
155
1100
394
3191
1.30
4.81
3.4
2.4
—
—
—
0
0
123
816
1.54
4.80
1.4
1.2
—
—
—
0
0
23
84
2.76
4.78
3.8
2.5
1.7
1.8
umol/l
0.39
23
78
1607
15314
1.35
4.78
19.3
12.8
4.0
4.0
mmol/l
0.10
1579
14926
353
2820
1.31
4.77
3.7
2.5
—
—
—
0
0
25
97
2.60
4.64
1.7
1.6
—
—
—
0
0
117
779
1.54
4.50
6.0
4.6
—
—
—
0
0
279
2173
1.33
4.50
4.4
2.7
1.2
0.8
e6/l
0.37
169
1191
31
137
2.28
4.39
2.9
3.4
—
—
—
0
0
81
498
1.65
4.36
5.6
4.4
0.2
0.3
g/l
1.45
53
283
44
225
1.98
4.32
5.6
4.2
—
—
—
0
0
263
2044
1.33
4.30
2.9
2.8
144.7
134.8
ug/g
0.15
225
1668
1169
10776
1.23
4.29
4.0
3.4
14.6
14.5
pmol/l
0.66
1099
9997
1595
15235
1.31
4.26
19.1
12.7
139.6
139.6
mmol/l
0.03
1568
14874
33
153
2.18
4.19
2.0
3.4
—
—
—
0
0
216
1641
1.36
4.11
1.7
1.6
—
—
—
0
0
68
408
1.69
4.03
2.8
2.3
10.2
10.5
mg/l
0.08
63
382
97
636
1.55
4.03
3.9
3.2
21.5
21.7
s
0.12
89
563
72
440
1.66
3.99
1.7
1.4
314.5
237.7
u/ml
0.94
48
253
130
909
1.46
3.98
7.9
4.3
1.2
1.2
mmol/l
0.96
118
807
138
977
1.45
3.96
1.2
1.2
161.0
151.1
iu/ml
0.12
54
367
119
823
1.48
3.86
3.6
2.8
198.2
131.2
ng/l
1.10
107
725
23
95
2.44
3.81
1.1
1.3
—
—
—
0
0
55
317
1.76
3.78
5.1
4.0
23.9
24.3
mmol/l
0.38
48
277
43
230
1.89
3.75
10.5
3.1
—
—
—
0
0
553
4780
1.22
3.74
3.6
3.0
57.3
46.6
ng/l
0.27
374
2847
350
2879
1.27
3.72
1.9
1.7
—
—
—
0
0
71
442
1.63
3.69
2.3
1.4
0.2
0.2
g/l
0.45
66
418
434
3668
1.24
3.63
2.1
2.0
—
—
—
0
0
51
292
1.77
3.60
1.3
1.6
1.0
0.9
g/l
0.18
35
228
78
501
1.58
3.57
1.2
1.2
—
—
—
0
0
7
9
7.80
3.56
3.9
2.4
—
—
—
0
0
294
2384
1.28
3.51
1.7
1.5
19.0
20.3
nmol/l
0.81
259
2110
216
1684
1.32
3.47
6.2
3.1
9.3
8.0
umol/l
0.31
186
1461
50
291
1.74
3.36
11.3
3.1
40.1
32.9
mg/l
0.42
37
227
50
291
1.74
3.36
11.3
3.1
74.4
77.4
mg/l
0.03
37
228
1596
15348
1.27
3.31
18.1
11.5
21.7
22.8
mg/l
0.68
1288
11797
1026
9463
1.19
3.31
5.3
3.6
—
—
—
0
0
14
48
2.93
3.30
10.3
5.7
19.5
48.3
g/mol
1.00
14
42
40
219
1.84
3.28
1.8
1.5
0.5
0.3
nmol/l
0.41
33
181
22
96
2.31
3.27
4.0
4.5
8.4
8.6
mg/l
0.07
17
85
567
4970
1.20
3.25
2.1
1.9
—
—
—
0
0
13
43
3.04
3.25
1.2
1.2
—
—
—
0
0
16
60
2.68
3.23
3.1
1.9
—
—
—
0
0
17
66
2.59
3.21
3.8
3.8
202.1
161.3
umol/l
0.22
11
36
49
289
1.71
3.16
11.2
3.1
27.5
3.2
ratio
—
5
37
926
8490
1.18
3.14
5.0
3.5
57.3
341.1
e6/l
—
9
88
171
1309
1.34
3.13
14.9
16.7
1.2
1.2
inr
0.01
28
192
1397
13272
1.21
3.12
4.5
3.9
1.9
2.4
mu/l
0.93
1322
12440
46
268
1.73
3.10
3.8
2.5
16.9
17.4
%
0.25
25
141
103
735
1.42
2.91
1.7
1.3
—
—
—
0
0
233
1880
1.27
2.90
2.7
3.1
2.4
2.4
mmol/l
0.42
208
1639
51
312
1.65
2.90
11.9
4.8
—
—
—
0
0
15
58
2.60
2.87
1.3
1.1
137.7
252.7
ng/l
—
7
16
151
1156
1.33
2.79
4.2
3.6
—
—
—
0
0
9
23
3.93
2.77
2.1
2.1
—
—
—
0
0
19
84
2.27
2.77
1.8
1.8
—
—
—
0
0
12
42
2.87
2.75
1.0
1.1
—
—
—
0
0
65
428
1.54
2.74
2.4
2.1
4.0
1.5
ug/l
0.79
58
394
134
1011
1.35
2.73
4.5
4.2
—
—
—
0
0
97
695
1.42
2.70
13.1
13.4
—
—
—
0
0
8
19
4.22
2.68
5.9
7.6
4.5
8.5
mmol/l
—
8
19
28
147
1.92
2.66
6.0
4.8
—
—
—
0
0
37
213
1.75
2.64
5.3
3.6
—
—
—
0
0
1209
11419
1.17
2.58
4.0
3.2
51.6
49.4
u/l
0.36
1155
10929
137
1047
1.33
2.58
1.5
1.3
427.9
238.8
u/ml
0.68
128
970
33
185
1.80
2.57
6.1
7.1
9.7
10.4
mg/l
0.43
26
172
78
542
1.46
2.57
2.2
2.2
—
—
—
0
0
48
300
1.62
2.54
1.1
1.1
—
—
—
0
0
278
2327
1.23
2.52
1.6
1.6
36100028.0
41999434.0
pmol/l
0.06
241
2031
17
75
2.28
2.51
1.2
1.1
1648.6
1469.3
miu/ml
0.20
17
75
709
6452
1.16
2.46
5.2
3.9
—
—
—
0
0
213
1736
1.26
2.46
1.2
1.2
—
—
—
0
0
749
6845
1.16
2.46
4.1
3.0
0.0
0.0
estimate
0.50
165
1277
10
34
2.95
2.41
2.3
2.3
—
—
—
0
0
10
34
2.95
2.41
1.1
1.3
—
—
—
0
0
1685
16416
1.26
2.40
19.1
12.7
79.1
76.7
umol/l
1.80
1685
16409
109
815
1.36
2.38
15.5
12.3
0.7
0.7
%
0.25
109
810
5
8
6.26
2.37
1.0
1.1
—
—
—
0
0
48
306
1.58
2.37
6.3
3.6
—
—
—
0
0
109
816
1.36
2.37
15.2
12.2
1.6
1.5
%
0.43
109
811
172
1374
1.28
2.36
11.9
9.9
0.2
0.9
mmol/l
1.12
134
1098
59
395
1.51
2.35
1.5
1.4
258.2
285.5
ug/g
0.42
29
231
120
913
1.34
2.35
4.0
3.1
—
—
—
0
0
748
6852
1.15
2.35
5.7
4.1
0.0
0.0
estimate
0.50
172
1343
27
148
1.84
2.29
1.4
1.2
—
—
—
0
0
18
85
2.13
2.29
5.7
4.6
—
—
—
0
0
102
761
1.36
2.28
1.8
1.6
331.6
299.9
mu/l
0.48
95
702
7
18
3.90
2.25
1.0
1.1
—
—
—
0
0
171
1379
1.26
2.18
11.9
9.9
5.0
5.2
kpa
1.17
165
1317
171
1379
1.26
2.18
11.9
9.9
12.2
12.7
kpa
0.67
164
1320
37
226
1.65
2.18
3.6
2.9
9.0
7.9
umol/l
0.19
30
175
8
24
3.34
2.18
1.8
2.3
—
—
—
0
0
6
14
4.30
2.15
1.7
1.4
—
—
—
0
0
18
88
2.06
2.11
1.4
1.2
—
46.7
—
0
6
750
6912
1.14
2.10
4.1
3.0
0.0
0.0
estimate
0.56
167
1252
65
456
1.44
2.09
1.4
1.3
93.3
118.1
titre
—
6
48
38
238
1.61
2.05
1.8
1.5
—
—
—
0
0
31
184
1.70
2.05
1.3
1.3
—
—
—
0
0
15
69
2.18
2.04
3.5
1.5
26.2
6.4
ug/l
0.46
15
62
12
50
2.41
2.02
1.8
1.3
—
—
—
0
0
12
50
2.41
2.02
4.0
2.6
38.4
99.9
ug/l
2.84
12
50
31
185
1.69
2.01
1.2
1.3
2.7
2.8
g/l
0.21
18
129
31
185
1.69
2.01
1.2
1.3
6.9
6.6
g/l
0.32
17
131
31
185
1.69
2.01
1.2
1.3
0.3
0.4
g/l
1.36
18
128
19
97
1.97
2.00
1.3
1.2
—
—
—
0
0
409
3623
1.16
1.98
1.4
1.4
1.5
2.4
u/ml
0.95
108
968
17
84
2.03
1.95
1.1
1.1
—
—
—
0
0
11
45
2.45
1.93
1.5
2.5
—
—
—
0
0
16
78
2.06
1.91
1.1
1.2
—
—
—
0
0
17
85
2.01
1.90
1.1
1.0
—
—
—
0
0
22
121
1.83
1.88
1.2
1.3
—
—
—
0
0
1683
16464
1.22
1.83
13.1
9.1
30.5
30.8
u/l
0.20
1646
16052
1666
16282
1.21
1.83
14.2
10.5
—
—
—
0
0
5
12
4.17
1.82
4.0
2.8
25.2
28.6
umol/l
—
5
12
415
3707
1.15
1.80
1.7
1.7
1.5
1.5
mmol/l
0.54
359
3232
8
29
2.77
1.79
1.4
1.3
—
—
—
0
0
23
131
1.77
1.78
1.8
2.2
32.0
33.2
pg
0.48
23
131
399
3557
1.15
1.77
4.4
3.3
0.0
0.0
estimate
0.05
165
1283
20
109
1.84
1.77
1.0
1.0
—
—
—
0
0
22
124
1.78
1.76
1.3
1.5
11.9
12.2
umol/l
0.09
22
116
9
36
2.51
1.74
2.0
3.1
—
—
—
0
0
5
13
3.85
1.71
8.6
5.2
—
—
—
0
0
5
13
3.85
1.71
4.0
2.7
38.6
34.6
umol/l
—
5
13
360
3194
1.16
1.71
2.3
2.0
1.3
1.0
mg/l
0.45
279
2373
35
226
1.56
1.71
2.4
2.4
—
—
—
0
0
50
352
1.43
1.63
3.5
3.5
34.4
38.1
umol/l
0.41
44
306
18
98
1.84
1.61
3.6
2.5
0.9
0.9
nmol/l
0.01
11
75
5
14
3.58
1.61
9.4
4.5
—
—
—
0
0
1381
13345
1.13
1.60
5.7
4.8
39.7
39.1
mmol/mol
1.14
1311
12723
33
214
1.55
1.60
1.2
1.2
—
—
—
0
0
232
2004
1.18
1.55
1.8
1.8
—
—
—
0
0
14
71
1.98
1.54
1.1
1.2
—
—
—
0
0
8
33
2.43
1.53
1.0
1.4
—
—
—
0
0
56
408
1.38
1.53
3.1
4.0
962.5
1162.5
u/ml
0.08
49
357
5
15
3.34
1.52
1.4
1.3
—
—
—
0
0
17
93
1.84
1.51
2.9
2.4
67.1
55.7
umol/l
0.72
17
82
7
27
2.60
1.51
1.3
2.3
—
—
—
0
0
21
123
1.72
1.51
1.5
1.2
—
—
—
0
0
33
218
1.52
1.49
1.5
1.5
—
—
—
0
0
23
139
1.66
1.48
4.2
5.4
11.0
11.9
%
0.47
23
139
19
109
1.75
1.47
1.3
1.1
—
—
—
0
0
218
2511
0.85
1.46
1.4
1.4
—
—
—
0
0
24
148
1.63
1.44
2.5
1.7
—
—
—
0
0
46
328
1.41
1.43
2.0
1.8
2.9
5.4
iu/l
1.68
14
123
6
22
2.73
1.43
1.3
5.1
—
—
—
0
0
42
295
1.43
1.42
1.1
1.1
—
—
—
0
0
116
948
1.24
1.40
4.0
4.7
18.8
26.3
ug/l
0.26
92
759
440
4012
1.13
1.39
3.5
2.6
—
—
—
0
0
14
74
1.90
1.39
1.1
1.2
—
—
—
0
0
1043
9964
1.11
1.38
3.7
3.2
—
—
—
0
0
5
17
2.95
1.36
2.6
3.9
—
—
—
0
0
20
120
1.67
1.34
2.9
4.1
55.5
57.5
%
0.13
15
86
264
2334
1.15
1.34
1.2
1.2
33.1
28.1
iu/ml
0.22
78
753
11
54
2.04
1.33
1.0
1.6
—
—
—
0
0
5
18
2.78
1.28
1.0
1.0
—
—
—
0
0
51
380
1.35
1.26
1.4
1.3
—
—
—
0
0
64
499
1.29
1.17
6.4
5.1
—
—
—
0
0
37
265
1.40
1.17
1.6
1.4
112.5
181.6
pmol/l
0.27
15
86
56
429
1.31
1.17
1.1
1.1
4.5
6.8
u/ml
0.62
31
253
17
102
1.67
1.16
1.0
1.0
—
—
—
0
0
0
33
0.00
1.16
0.0
8.0
—
—
—
0
0
38
275
1.39
1.14
3.7
2.3
132.3
136.0
g/l
0.34
27
204
95
782
1.23
1.12
3.6
3.4
4.6
4.7
pmol/l
0.65
89
712
23
151
1.53
1.11
1.4
1.2
—
—
—
0
0
5
21
2.38
1.09
2.0
2.3
—
—
—
0
0
12
66
1.82
1.09
1.9
1.5
—
—
—
0
0
19
120
1.59
1.08
1.8
1.9
—
—
—
0
0
27
185
1.47
1.08
1.5
1.4
77.4
74.9
mmol/l
0.10
19
155
54
417
1.30
1.08
1.2
1.2
—
—
—
0
0
111
940
1.19
1.00
1.6
1.4
—
—
—
0
0
17
107
1.59
0.99
3.1
2.5
—
—
—
0
0
19
123
1.55
0.99
3.0
2.7
—
—
—
0
0
102
858
1.20
0.99
1.2
1.2
—
—
—
0
0
9
49
1.84
0.98
1.0
1.1
—
—
—
0
0
74
605
1.23
0.96
1.3
1.3
188.5
230.8
miu/ml
0.47
28
275
13
77
1.69
0.95
1.1
1.2
0.6
2.4
u/ml
—
6
50
32
234
1.37
0.93
4.8
3.4
—
—
—
0
0
20
135
1.49
0.89
1.0
1.1
0.9
2.2
u/ml
—
8
50
29
211
1.38
0.88
1.9
1.7
—
—
—
0
0
18
119
1.52
0.88
1.4
1.4
15112.5
93196.6
e6/l
0.73
13
92
57
459
1.25
0.86
2.4
2.8
—
—
—
0
0
19
128
1.49
0.86
1.2
1.1
—
—
—
0
0
15
96
1.57
0.84
1.9
4.1
0.6
1.7
ug/l
3.60
15
91
169
1507
1.13
0.82
1.3
1.2
—
—
—
0
0
82
968
0.84
0.81
1.4
1.6
—
—
—
0
0
8
47
1.71
0.80
1.8
2.6
—
—
—
0
0
90
768
1.18
0.79
4.9
5.9
—
—
—
0
0
16
106
1.51
0.79
1.1
1.5
0.2
0.6
u/ml
—
6
43
19
131
1.45
0.78
1.0
1.2
0.3
2.0
u/ml
—
9
54
1444
14167
1.08
0.77
4.1
3.8
6.0
5.9
mmol/l
0.85
1368
13293
90
770
1.18
0.77
2.5
2.1
—
—
—
0
0
38
296
1.29
0.77
1.2
1.2
2.9
4.8
u/ml
1.02
18
131
160
1787
0.89
0.77
1.6
1.7
—
—
—
0
0
271
2494
1.10
0.76
4.4
3.5
949.5
705.2
ng/l
0.24
203
1748
11
67
1.65
0.75
1.3
1.7
0.9
3.3
u/field
0.52
11
55
13
83
1.57
0.75
1.5
1.4
—
—
—
0
0
1366
13380
1.08
0.74
21.1
14.1
13.5
13.4
%
1.07
1346
13113
5
24
2.09
0.74
1.4
1.3
—
—
—
0
0
51
416
1.23
0.72
1.1
1.1
1.0
1.2
u/ml
0.18
25
217
316
2938
1.09
0.72
4.1
3.1
1.0
1.0
kg/l
0.35
49
419
1473
14479
1.08
0.71
4.0
3.6
1.4
1.4
mmol/l
0.03
1395
13774
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
5
26
1.93
0.70
1.6
1.1
—
—
—
0
0
5
26
1.93
0.70
1.0
1.2
—
—
—
0
0
11
170
0.64
0.70
10.0
20.5
1278.5
1412.0
nmol/l
0.21
11
165
122
1079
1.14
0.69
1.9
2.1
—
—
—
0
0
57
473
1.21
0.69
1.1
1.2
2.3
2.3
u/ml
0.01
28
225
17
118
1.44
0.69
1.5
1.6
34.7
29.9
%
0.22
12
83
19
135
1.41
0.69
1.1
1.1
—
—
—
0
0
5
91
0.55
0.67
1.6
1.4
—
—
—
0
0
24
179
1.35
0.67
2.0
1.4
1.9
1.4
promille
0.48
16
140
236
2177
1.10
0.65
1.2
1.2
10.7
10.2
u/ml
0.04
88
906
7
44
1.59
0.65
1.9
2.7
—
—
—
0
0
32
251
1.28
0.64
1.3
1.5
—
—
—
0
0
68
580
1.18
0.63
1.6
1.6
—
—
—
0
0
60
708
0.84
0.63
1.7
1.6
—
—
—
0
0
61
516
1.19
0.62
5.3
2.6
—
—
—
0
0
51
424
1.21
0.62
1.3
1.4
—
—
—
0
0
1537
15155
1.08
0.62
4.7
4.2
2.8
2.9
mmol/l
1.12
1458
14407
20
147
1.36
0.61
1.8
1.7
55.8
54.2
%
0.06
15
106
1415
14378
0.94
0.61
21.0
14.1
335.0
335.1
g/l
0.16
1409
14284
26
200
1.30
0.60
1.5
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
10.8
—
—
—
0
0
84
734
1.15
0.59
2.2
2.4
12119.6
3950.0
u/l
0.88
35
275
21
157
1.34
0.59
1.3
1.2
290.0
166.2
titre
—
5
32
120
1075
1.12
0.58
1.9
2.0
—
—
—
0
0
325
3056
1.08
0.58
4.4
2.9
—
—
—
0
0
64
549
1.17
0.57
1.5
1.7
—
—
—
0
0
146
1326
1.11
0.57
1.2
1.2
—
—
—
0
0
34
274
1.25
0.57
1.1
1.1
1.7
3.3
u/ml
0.79
16
135
16
115
1.39
0.56
1.3
1.1
—
—
—
0
0
121
1089
1.12
0.55
1.9
2.1
—
—
—
0
0
48
403
1.20
0.55
1.1
1.1
1.7
3.5
u/ml
0.62
12
103
121
1092
1.12
0.53
1.9
2.1
—
—
—
0
0
6
97
0.62
0.52
3.0
2.7
—
—
—
0
0
29
233
1.25
0.51
2.1
4.3
307.5
306.4
u/ml
0.00
29
220
28
224
1.25
0.51
1.6
1.3
—
—
—
0
0
48
407
1.18
0.51
1.7
2.0
1.2
0.8
nmol/l
1.09
41
348
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
14
101
1.39
0.49
1.1
1.1
—
—
—
0
0
11
76
1.45
0.48
1.1
1.0
—
—
—
0
0
10
68
1.47
0.47
1.2
1.4
143.0
152.2
nmol/l
—
10
68
7
48
1.46
0.46
1.9
1.3
—
—
—
0
0
34
282
1.21
0.46
1.1
1.1
7.1
6.5
u/ml
0.05
15
127
169
1820
0.92
0.45
1.7
1.4
—
—
—
0
0
38
320
1.19
0.45
1.3
1.2
—
—
—
0
0
33
274
1.21
0.45
1.2
1.2
—
—
—
0
0
15
112
1.34
0.44
1.1
1.1
0.2
5.2
u/ml
—
5
20
165
1531
1.09
0.44
1.5
1.4
—
—
—
0
0
1520
15030
1.06
0.44
4.4
4.0
4.6
4.7
mmol/l
2.16
1451
14371
10
69
1.45
0.44
1.6
2.0
—
34.3
—
0
9
5
31
1.61
0.43
2.2
1.4
—
—
—
0
0
8
56
1.43
0.42
1.6
1.1
—
—
—
0
0
16
122
1.31
0.42
1.7
1.5
—
72.4
—
0
16
94
852
1.11
0.41
1.9
2.1
—
—
—
0
0
8
58
1.38
0.41
1.0
1.1
—
—
—
0
0
5
33
1.52
0.41
3.2
2.6
—
—
—
0
0
239
2257
1.07
0.41
1.7
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
12
88
1.37
0.40
1.5
1.5
—
—
—
0
0
10
71
1.41
0.39
1.2
1.1
—
11.1
—
0
14
111
1019
1.09
0.39
1.9
2.1
—
—
—
0
0
83
751
1.11
0.39
7.7
8.3
23.9
24.5
mmol/l
0.62
77
695
79
714
1.11
0.38
2.6
2.9
—
—
—
0
0
38
327
1.17
0.37
1.1
1.1
85.7
101.4
iu/ml
—
6
88
9
69
1.31
0.37
1.0
1.2
—
—
—
0
0
5
37
1.35
0.37
1.2
1.4
—
—
—
0
0
5
37
1.35
0.37
1.2
1.4
—
—
—
0
0
5
37
1.35
0.37
1.2
1.4
—
—
—
0
0
25
207
1.21
0.36
2.3
2.2
—
—
—
0
0
51
452
1.13
0.34
7.8
8.4
—
—
—
0
0
11
82
1.34
0.34
1.0
1.1
102.4
214.1
iu/ml
1.98
11
82
34
293
1.16
0.33
1.2
1.2
—
—
—
0
0
1511
14972
1.05
0.33
4.5
3.9
1.3
1.4
mmol/l
1.00
1435
14275
50
447
1.12
0.31
5.1
4.6
1.8
1.3
mmol/l
0.87
50
439
32
278
1.15
0.29
5.5
9.0
11.5
11.5
mmol/l
0.04
27
245
380
3924
0.96
0.28
2.5
2.4
0.7
0.7
ug/l
0.15
187
2105
28
323
0.86
0.28
3.1
2.4
158.3
152.1
ug/min
0.02
17
212
652
6664
0.97
0.28
2.7
2.5
—
—
—
0
0
26
223
1.17
0.28
4.5
4.3
981.3
248.4
u/ml
0.69
26
206
8
62
1.29
0.28
2.5
1.4
—
—
—
0
0
135
1431
0.94
0.28
1.5
1.4
—
—
—
0
0
54
491
1.10
0.26
1.0
1.1
—
—
—
0
0
109
1023
1.07
0.26
3.2
2.9
4.4
4.1
e9/l
0.40
79
873
10
77
1.30
0.26
1.5
1.7
—
—
—
0
0
9
73
1.23
0.25
1.3
1.2
—
—
—
0
0
479
4677
1.03
0.23
1.6
1.5
—
—
—
0
0
109
1028
1.06
0.23
2.4
2.3
13.0
10.0
ug/l
0.31
102
937
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
28
247
1.14
0.22
1.3
1.2
37.8
28.4
u/l
0.21
28
213
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
4.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
1775
17693
1.06
0.21
24.5
16.7
6.7
6.7
e9/l
0.15
1744
17260
665
6538
1.03
0.21
3.5
3.4
1.7
1.8
ug/l
0.22
610
6066
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
35
316
1.11
0.20
1.1
1.1
11.1
3.9
u/ml
0.58
15
129
1774
17684
1.06
0.20
24.4
16.6
30.3
30.2
pg
0.28
1765
17499
1774
17686
1.06
0.19
24.4
16.6
90.2
90.0
fl
1.07
1765
17501
10
81
1.24
0.18
4.8
2.7
1921.9
2167.6
ml
—
10
76
1774
17688
1.05
0.18
24.5
16.7
4.6
4.7
e12/l
2.40
1744
17262
1772
17668
1.05
0.18
24.5
16.7
251.1
250.2
e9/l
0.24
1749
17270
7
59
1.19
0.18
1.7
1.4
—
—
—
0
0
7
61
1.15
0.17
1.4
1.2
—
—
—
0
0
22
195
1.13
0.17
1.2
1.4
70.9
113.5
pmol/l
0.35
22
188
90
947
0.95
0.17
1.1
1.1
—
—
—
0
0
17
148
1.15
0.17
1.2
1.4
12.3
12.0
mmol/l
—
9
46
8
68
1.18
0.16
1.1
1.0
—
5.3
—
0
8
1774
17693
1.05
0.16
24.8
16.8
139.8
141.0
g/l
2.53
1763
17509
20
179
1.12
0.14
1.1
1.1
—
—
—
0
0
67
641
1.05
0.11
1.1
1.1
—
—
—
0
0
28
261
1.07
0.10
2.3
1.8
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
41
389
1.06
0.09
2.4
2.2
26.8
44.7
u/ml
0.75
41
369
5
65
0.77
0.08
12.2
7.5
—
—
—
0
0
15
164
0.91
0.08
1.3
1.3
—
—
nmol/l
—
0
0
8
77
1.04
0.07
1.5
1.3
—
—
—
0
0
36
377
0.95
0.07
1.1
1.1
—
—
—
0
0
9
86
1.05
0.07
1.6
1.5
—
—
—
0
0
29
275
1.06
0.06
2.8
3.3
24.3
27.4
mg/l
0.16
16
169
12
110
1.09
0.05
1.1
1.2
1.0
1.1
ratio
—
7
40
12
110
1.09
0.05
1.1
1.2
—
—
—
0
0
29
278
1.04
0.04
1.1
1.2
—
—
—
0
0
17
160
1.06
0.04
1.2
1.4
—
—
—
0
0
37
358
1.03
0.04
2.2
2.4
—
—
—
0
0
13
121
1.07
0.03
1.1
1.1
5.0
6.5
iu/ml
—
5
30
10
92
1.09
0.03
1.0
1.3
—
—
—
0
0
37
379
0.98
0.02
1.1
1.1
—
—
—
0
0
1528
15291
1.00
0.01
18.2
12.3
40.9
41.5
%
2.04
1227
12637
17
176
0.97
0.00
1.2
1.3
—
0.3
nmol/l
—
0
13
37
376
0.98
0.00
1.6
1.5
—
—
—
0
0
11
115
0.96
0.00
1.2
1.2
—
—
—
0
0
13
125
1.04
0.00
4.6
4.7
392.7
75.6
u/ml
—
6
40
13
125
1.04
0.00
13.3
12.3
0.7
0.6
mmol/l
0.31
13
116
27
269
1.00
0.00
1.1
1.1
0.0
0.5
u/ml
—
5
76
37
368
1.01
0.00
1.5
1.4
—
—
—
0
0
18
178
1.01
0.00
1.2
1.4
0.5
0.6
nmol/l
0.23
18
168
37
367
1.01
0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
1381.3
—
0
5
0
6
0.00
0.00
0.0
1.0
—
133.9
—
0
6
0
6
0.00
0.00
0.0
1.0
—
36.6
—
0
6
0
8
0.00
0.00
0.0
2.0
—
188.1
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
0.00
1.1
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
95
0.95
0.00
1.6
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
2.0
2.3
18.6
15.8
umol/l
—
5
52
7
71
0.99
0.00
1.4
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
8
84
0.95
0.00
2.4
2.1
241.1
146.9
nmol/l
—
8
75
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_VARICELLA and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VARICELLA 2.371 [1.77, 3.17] < 0.001
Birth year 0.998 [0.99, 1.01] 0.578

During the follow-up period (1.1.1998 — 31.12.2019), 230 out of 5335 females with AB1_VARICELLA died.

Males

Parameter HR [95% CI] p-value
AB1_VARICELLA 2.514 [1.95, 3.24] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 291 out of 6337 males with AB1_VARICELLA died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VARICELLA.

N-year risk Females Males
1 0.272% 0.409%
5 1.555% 2.968%
10 3.899% 7.396%
15 7.226% 14.074%
20 12.554% 22.812%

Relationships between endpoints

Index endpoint: AB1_VARICELLA – Varicella [chickenpox]

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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