No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
93 |
4. Check minimum number of eventsNone |
93 |
5. Include endpointsNone |
93 |
6. Filter based on genotype QC (FinnGen only) |
88 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H50
- Name in latin
- Strabismus mechanicus
Similar endpoints
↥List of similar endpoints to
Mechanical strabismus
based on the number of shared cases.
Similar with more cases:
- Other strabismus
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 628 | 362 | 266 |
| Only index persons | 526 | 307 | 219 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 33.99 | 31.00 |
| Only index persons | 44.68 | 45.23 | 43.92 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 88 | 60 | 28 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 56.39 | 53.84 | 61.86 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 93
- Matched controls
- 930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
134.0
93
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
29.8
51.0
39
22
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
668.9
42.8
39
*
H03BB01
ATC
carbimazole; oral
19.8
35.8
32
24
H53.2
ICD-10 Finland
Diplopia
115.3
34.9
36
5
XCW99
NOMESCO Finland
Other investigative procedure of eye
15.0
34.3
38
41
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
31.0
28
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
26.3
24
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
25.1
23
*
H50.2
ICD-10 Finland
Vertical strabismus
+∞
25.1
23
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
22.8
21
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
7.0
18.9
41
94
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
21.1
16.3
24
15
H50.8
ICD-10 Finland
Other specified strabismus
+∞
15.0
14
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
13.9
13
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
149.3
12.8
13
*
H03AA01
ATC
levothyroxine sodium; systemic
4.8
12.7
45
152
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
11.7
11
*
CE2W4
NOMESCO Finland
Eye movement mapping
+∞
11.7
11
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
11.7
11
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
+∞
10.6
10
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
5.3
10.1
24
57
ZXA10
NOMESCO Finland
Bilateral
4.5
9.9
32
98
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.7
8.7
57
280
L04AX03
ATC
methotrexate; systemic
5.3
8.6
20
46
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
5.3
8.6
20
46
H50.52
ICD-10 Finland
Exophoria
98.6
8.6
9
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
98.6
8.6
9
*
WX002
NOMESCO Finland
Sedation and analgesia
4.1
8.5
30
97
CAC44
NOMESCO Finland
Combined decompression of orbit
+∞
8.5
8
*
WF002
NOMESCO Finland
Radical radiotherapy
7.7
8.3
19
30
H02AB06
ATC
prednisolone; systemic
3.5
8.0
59
307
XCK00
NOMESCO Finland
Perimetry
10.3
7.9
15
17
BAA60
NOMESCO Finland
Total thyroidectomy
11.5
7.8
14
14
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
20.5
7.8
11
6
CAC10
NOMESCO Finland
Reconstruction of orbital wall using bone graft or plate
+∞
7.4
7
*
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
+∞
7.4
7
*
T85
ICPC
Hyperthyroidism/thyrotoxicosis
+∞
7.4
7
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
7.4
7
*
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
7.4
7
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.3
7.3
44
200
WX402
NOMESCO Finland
General anaesthesia
3.5
7.2
33
126
ZX120
NOMESCO Finland
Intravenous
4.6
6.8
18
46
104
Kela drug reimbursment
Thyroid insufficiency
6.3
6.5
17
32
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
6.3
6
*
ZXA00
NOMESCO Finland
Right side
3.1
6.2
34
144
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.1
6.1
19
55
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
32
27
17.54
33.47
8.3
2.2
6.58
6.98
iu/l
0.06
27
11
30
59
7.03
15.84
8.4
3.7
4.31
4.64
pmol/l
1.11
30
53
71
459
3.31
5.93
11.4
8.6
3.78
3.94
e9/l
0.25
59
395
17
67
2.88
3.35
1.6
1.3
224.38
133.93
iu/ml
—
8
28
85
725
3.00
2.74
12.5
11.5
85.01
84.99
ml/min/173m2
0.00
72
586
7
16
4.64
2.52
1.7
1.3
—
—
—
0
0
41
271
1.92
2.38
2.9
2.9
—
—
—
0
0
53
386
1.87
2.25
5.4
4.8
0.00
0.00
estimate
-0.00
16
88
53
391
1.83
2.11
4.3
3.6
0.00
0.00
estimate
-0.00
15
87
47
339
1.78
1.98
2.7
2.1
71.68
74.04
nmol/l
0.23
40
300
52
388
1.77
1.94
4.0
3.5
0.00
0.00
estimate
-0.00
16
98
56
428
1.78
1.91
4.6
3.6
5.96
6.43
mmol/l
1.83
51
393
49
365
1.72
1.79
7.0
5.6
1.22
1.22
mmol/l
0.14
44
316
7
26
2.83
1.61
1.4
1.3
—
—
—
0
0
12
61
2.11
1.40
2.8
2.1
382.17
353.64
nmol/l
0.18
12
56
27
181
1.69
1.40
1.7
1.9
—
—
—
0
0
13
69
2.03
1.36
1.6
1.3
—
—
—
0
0
31
218
1.63
1.33
4.2
3.6
0.00
0.00
estimate
-0.00
16
88
5
18
2.87
1.30
13.2
4.8
24.78
24.53
mmol/l
—
5
18
13
71
1.97
1.27
1.6
1.4
—
—
—
0
0
17
104
1.78
1.19
1.8
3.2
0.79
0.74
ug/l
0.08
11
70
78
695
1.76
1.17
22.0
14.2
13.50
14.87
%
6.71
78
690
20
132
1.66
1.08
2.9
2.5
4.21
2.32
e6/l
0.22
14
74
85
790
1.88
0.92
14.3
12.0
27.19
21.49
mg/l
0.58
65
601
45
372
1.41
0.84
2.3
2.4
—
—
—
0
0
20
144
1.50
0.76
3.5
4.6
23.84
20.65
%
—
8
72
7
40
1.81
0.73
1.1
1.9
—
—
—
0
0
8
128
0.59
0.70
2.9
2.2
—
—
—
0
0
76
700
1.47
0.68
5.0
5.1
36.59
38.92
mmol/mol
2.81
76
664
5
28
1.83
0.67
1.2
1.3
—
—
—
0
0
7
115
0.58
0.62
2.9
2.0
—
—
—
0
0
8
52
1.59
0.61
1.3
1.9
—
—
—
0
0
6
37
1.66
0.57
1.2
1.6
—
—
—
0
0
36
304
1.30
0.54
4.9
3.6
—
—
—
0
0
12
87
1.44
0.45
4.3
7.6
—
—
—
0
0
14
105
1.39
0.44
1.8
1.7
—
—
—
0
0
5
31
1.65
0.44
23.6
4.6
1.42
1.63
%
—
5
31
5
31
1.65
0.44
23.6
4.6
0.84
0.70
%
—
5
31
8
57
1.44
0.43
1.4
1.4
—
—
—
0
0
10
71
1.46
0.41
2.3
3.4
—
—
—
0
0
17
140
1.26
0.30
2.9
2.4
0.42
1.02
e6/l
1.22
12
82
50
539
0.84
0.30
3.2
3.3
—
—
—
0
0
15
180
0.80
0.27
1.5
1.4
19.89
21.36
nmol/l
0.20
15
151
34
308
1.16
0.24
12.9
11.6
0.98
1.17
inr
—
10
91
18
155
1.20
0.22
1.4
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
32
293
1.14
0.19
2.0
1.8
103.91
98.90
pmol/l
0.29
14
145
28
256
1.13
0.17
2.4
3.8
12.66
27.44
ng/l
2.52
13
174
6
57
1.06
0.09
1.3
2.9
35.33
71.86
ng/l
—
6
51
5
60
0.82
0.08
2.6
4.7
1.25
1.22
mmol/l
—
5
53
7
80
0.86
0.07
15.6
4.0
106.14
104.28
mmol/l
—
7
80
14
152
0.91
0.06
1.5
1.6
1.64
0.89
mg/l
—
8
116
11
100
1.11
0.05
1.4
2.0
2.29
2.47
g/l
0.66
11
90
16
167
0.95
0.01
1.3
1.5
—
—
—
0
0
18
174
1.04
0.00
1.7
3.1
261.15
1079.85
ng/l
4.49
13
152
11
107
1.03
0.00
1.5
2.0
14.65
14.11
umol/l
0.09
11
101
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.0
—
137.20
—
0
5
0
5
0.00
0.00
0.0
1.0
—
4.06
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
5.92
—
0
5
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
252.95
—
0
6
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
24.07
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
-0.00
0.0
1.0
—
118.33
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
46.71
—
0
7
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
117.86
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
13.14
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_STRABMECH and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have H7_STRABMECH.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: H7_STRABMECH – Mechanical strabismus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data