Mechanical strabismus

H7_STRABMECH

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H50.6 Cause of death: ICD-10 — H50.6 2 out of 7 registries used, show all original rules.	81
4. Check minimum number of events None	81
5. Include endpoints None	81
6. Filter based on genotype QC (FinnGen only)	81

Control definitions (FinnGen only)

Control exclude: H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H50
Name in latin: Strabismus mechanicus

NAME	H7_STRABMECH
CONTROL_EXCLUDE	H7_OCUMUSCLE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H506
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H506
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Mechanical strabismus based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	628	362	266
Only index persons	526	307	219
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	-	33.99	31.00
Only index persons	44.68	45.23	43.92

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	81	56	25
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	54.61	51.62	61.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
71: Matched controls
709

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H50.6

ICD-10 Finland

Mechanical strabismus

+∞

102.0

H53.2

ICD-10 Finland

Diplopia

94.3

30.4

H06.2*E05.9

ICD-10 Finland

Dysthyroid exophthalmos

150.5

28.1

CEC00

NOMESCO Finland

Recession of extraocular muscle

+∞

26.8

CEW99

NOMESCO Finland

Other operation on extraocular muscle

+∞

24.4

H50.2

ICD-10 Finland

Vertical strabismus

+∞

22.0

CEC60

NOMESCO Finland

Transposition of extraocular muscle with adjustable suture

+∞

20.8

H50.0

ICD-10 Finland

Convergent concomitant strabismus

+∞

20.8

H06.2

ICD-10 Finland

Dysthyroid exophthalmos

+∞

20.8

E05.0

ICD-10 Finland

Thyrotoxicosis with diffuse goitre

24.9

20.3

XCW99

NOMESCO Finland

Other investigative procedure of eye

14.1

17.8

H50.8

ICD-10 Finland

Other specified strabismus

+∞

12.9

H03BB01

ATC

carbimazole; oral

12.7

12.1

CA1BG

NOMESCO Finland

Eye and orbita MRI examination with high intensity magnet

142.1

11.8

CE2W4

NOMESCO Finland

Eye movement mapping

+∞

11.8

CEC10

NOMESCO Finland

Recession and resection of extraocular muscle

+∞

10.7

E05.9

ICD-10 Finland

Thyrotoxicosis, unspecified

13.4

9.4

H03AA01

ATC

levothyroxine sodium; systemic

5.1

9.2

125

CEC90

NOMESCO Finland

Total transposition of extraocular muscle or muscles

+∞

8.5

WX100

NOMESCO Finland

Conjunctival surface anesthesia

7.8

8.5

XCD10

NOMESCO Finland

Electrophysiological examination of eye

38.2

8.3

WF002

NOMESCO Finland

Radical radiotherapy

14.1

8.0

ZXA10

NOMESCO Finland

Bilateral

5.1

7.9

CK2X4

NOMESCO Finland

Optical coherence tomography (OCT) of ocular fundus

8.6

7.9

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

4.3

7.7

151

CA1CG

NOMESCO Finland

Eye and orbita extensive MRI examination with high intensity magnet

89.0

7.6

CAC44

NOMESCO Finland

Combined decompression of orbit

+∞

7.4

CAC10

NOMESCO Finland

Reconstruction of orbital wall using bone graft or plate

+∞

7.4

CAC30

NOMESCO Finland

Decompression of orbit to sinuses

+∞

7.4

H50.1

ICD-10 Finland

Divergent concomitant strabismus

+∞

7.4

S02.30

ICD-10 Finland

Fracture of orbital floor, closed

76.4

6.5

ZX050

NOMESCO Finland

Stereotactic radiotherapy

+∞

6.3

CEC30

NOMESCO Finland

Resection of extraocular muscle

+∞

6.3

CS444

NOMESCO Finland

Visual field testing with Octopus automated perimetry

14.3

6.3

L04AX03

ATC

methotrexate; systemic (immunosuppressants)

5.7

6.2

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3013650) Neutrophils [#/volume] in Blood by Automated count

395

3.00

4.63

9.8

8.5

3.9

e9/l

0.09

337

(40758558) Short blood count panel - Blood

160

2.15

2.53

5.6

5.9

—

(40761536) Microorganisms panel - Urine sediment

2.66

2.45

7.9

3.4

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

2.62

2.26

1.7

1.3

163.7

136.8

iu/ml

—

(3018418) pH of Serum or Plasma

192

2.00

2.23

3.8

3.6

7.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

625

2.70

2.18

12.2

11.2

83.8

84.8

ml/min/173m2

0.18

499

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

228

1.94

2.17

2.9

2.8

—

(3026008) Bacteria identified in Urine by Culture

203

1.95

2.13

3.4

2.8

—

(3044889) 12 lead EKG panel

463

2.01

2.05

3.1

3.4

—

(40768443) Skin Pathology biopsy report

3.55

2.01

1.1

1.0

—

(3002256) Pathology report gross observation

2.25

1.96

1.3

1.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

620

2.45

1.95

16.6

12.2

39.3

39.9

0.31

471

(3029937) Albumin [Presence] in Urine by Test strip

183

1.91

1.94

4.3

3.5

0.0

estimate

0.00

(36304419) Bacteria [Presence] in Urine

184

1.90

2.7

2.6

—

(3021601) Nitrite [Presence] in Urine by Test strip

331

1.81

1.83

5.2

4.8

0.0

estimate

0.00

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.24

1.77

1.1

1.5

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

3.09

1.76

1.4

1.3

—

(3009261) Glucose [Presence] in Urine by Test strip

336

1.76

1.70

4.4

3.5

0.0

estimate

0.00

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

291

1.74

1.63

2.5

2.1

71.4

72.6

nmol/l

0.09

255

(3035350) Ketones [Presence] in Urine by Test strip

329

1.74

1.63

4.0

3.4

0.0

estimate

0.00

(3018095) Leukocytes [#/volume] in Urine

242

1.70

1.47

3.5

3.4

24.2

41.3

e6/l

0.44

166

(3011397) Hemoglobin [Presence] in Urine by Test strip

141

1.77

1.36

1.6

3.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.23

1.35

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

212

1.66

1.31

1.8

2.0

—

(3021589) Normoblasts [#/volume] in Blood

305

1.62

1.29

7.9

8.2

0.0

e9/l

0.49

243

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

1.84

1.17

1.8

3.1

0.8

0.7

ug/l

—

(3002385) Erythrocyte distribution width [Ratio]

578

1.77

1.15

21.0

14.5

13.5

13.6

0.25

572

(40768804) Tissue Pathology biopsy report

264

1.57

1.15

2.5

2.0

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

312

1.56

1.13

6.7

5.4

1.2

mmol/l

0.28

267

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.22

1.08

1.1

2.0

—

(3006315) Basophils [#/volume] in Blood

334

1.53

1.07

6.5

4.6

0.0

e9/l

0.04

289

(3000494) Fungus identified in Specimen by Culture

1.84

0.99

1.4

1.3

—

(42870588) Differential panel, method unspecified - Blood

216

1.53

0.98

6.0

3.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

104

1.67

0.93

1.4

1.6

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

230

1.48

0.88

2.8

3.2

2.4

mmol/l

0.24

197

(3001604) Monocytes [#/volume] in Blood

335

1.45

0.87

6.6

4.6

0.6

e9/l

0.19

289

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

260

1.45

0.84

4.8

3.5

—

(3015736) pH of Urine

251

1.45

0.83

3.3

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

271

1.44

0.81

4.3

3.7

35.3

35.9

g/l

0.27

257

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.70

0.80

4.3

7.5

—

(3023368) Bacteria identified in Blood by Culture

144

1.52

0.78

5.1

4.0

—

(3011288) Drugs identified in Urine by Screen method

2.25

0.77

1.2

1.7

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.68

0.75

2.2

3.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

155

1.48

0.73

1.6

1.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.73

0.72

1.7

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.91

0.69

1.2

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

193

1.43

0.69

5.6

3.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

101

0.56

0.67

2.8

2.0

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.65

0.67

1.3

2.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.67

0.65

1.7

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

111

0.60

0.64

2.6

2.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.61

0.63

1.2

2.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

124

1.47

0.62

3.8

4.2

22.5

21.8

—

(3037467) Urinalysis macro (dipstick) panel - Urine

470

1.37

0.62

7.2

4.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

686

1.65

0.60

13.8

12.0

30.0

20.9

mg/l

0.92

520

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

608

1.46

0.60

5.0

5.2

36.3

39.0

mmol/mol

3.51

576

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.60

0.0

1.5

—

(4035726)

1.53

0.56

1.6

1.3

—

(3026493) Urate [Moles/volume] in Serum or Plasma

166

0.67

0.55

1.8

2.4

313.5

4144.1

umol/l

0.79

145

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

325

1.32

0.54

3.5

3.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.56

0.52

2.0

1.7

—

(3022621) pH of Urine by Test strip

1.50

0.48

4.1

2.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

131

1.38

0.47

1.8

2.1

—

(3021960) Folate [Moles/volume] in Serum or Plasma

161

0.70

0.47

1.7

1.4

18.9

20.9

nmol/l

0.23

136

(3022145) Colonoscopy Study observation

1.47

0.46

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

469

0.78

0.45

3.2

3.1

—

(3016879) Cocaine [Presence] in Urine

1.65

0.44

1.2

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

1.60

0.43

1.2

1.3

—

(3027008) Opiates [Presence] in Urine

1.55

0.42

1.2

1.3

—

(3027944) Amphetamines [Presence] in Urine

1.55

0.42

1.2

1.3

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.41

0.0

2.1

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.41

0.0

1.1

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.41

0.0

1.7

—

(3028300) Cannabinoids [Presence] in Urine

1.50

0.41

1.2

1.4

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.40

0.0

5.0

—

(40761535) Cells panel - Urine sediment

1.39

0.35

1.7

3.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.41

0.32

1.4

—

(36660697) Celiac disease serology panel - Serum

1.26

0.28

1.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

153

1.23

0.25

7.3

4.3

—

(40761511) CBC panel - Blood by Automated count

717

1.37

0.24

14.3

11.6

—

(3000991) Gas panel - Venous blood

1.34

0.23

13.6

3.4

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.1

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

1.1

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.21

0.0

1.5

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.21

0.0

1.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

3.5

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

1.4

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.9

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.8

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(3037522) Nuclear Ab [Titer] in Serum

1.26

0.20

1.2

1.3

—

735.6

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.20

0.0

3.4

—

6.2

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.22

0.20

1.3

3.0

35.3

70.8

ng/l

—

(3012544) pH of Venous blood

1.17

0.19

1.2

3.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

139

1.19

0.18

1.4

—

(21494755) Public health laboratory ask at order entry panel

0.75

0.17

1.0

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

257

1.14

0.16

2.0

1.8

104.9

97.9

pmol/l

0.41

125

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.21

0.15

1.9

1.6

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

0.78

0.15

1.6

2.0

2.2

2.5

g/l

—

(1761868) Lipid panel - Serum or Plasma

227

0.90

0.10

2.5

2.8

—

(3013512) EKG study

185

0.90

0.09

2.9

3.4

—

(4010399)

1.14

0.09

1.8

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.07

0.08

1.4

1.9

—

(40768797) Stomach Pathology biopsy report

1.08

0.07

1.0

1.3

—

(3042936) Bacteria identified in Isolate by Culture

1.05

0.07

1.8

2.1

—

(3022948) Iron [Moles/volume] in Serum or Plasma

0.83

0.07

1.6

2.0

12.6

14.0

umol/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

229

1.07

0.05

2.4

3.3

13.0

25.5

ng/l

2.02

153

(3007164) IgA [Mass/volume] in Serum or Plasma

158

0.94

0.02

1.4

1.5

1.6

2.3

g/l

—

(3003694) ABO and Rh group [Type] in Blood

197

0.95

0.01

1.4

1.5

—

(3032080) INR in Blood by Coagulation assay

235

0.97

0.00

4.2

6.7

1.0

1.2

inr

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

141

0.99

0.00

1.4

1.5

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

0.0

3.6

—

0.8

—

(4146454)

0.00

0.0

3.4

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

2.7

—

24.1

—

(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

118.3

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.3

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.0

1.0

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.2

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

3.1

—

4.1

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.5

—

31.9

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

227.8

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.02

0.00

2.6

4.9

1.3

1.2

mmol/l

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

2.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

2.8

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

0.0

2.0

—

12.3

—

(4027681)

0.00

0.0

1.2

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

0.4

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

10.7

—

0.7

—

(4024509)

0.00

0.0

1.3

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.4

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.5

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

2.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

3.1

—

107.9

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.0

—

6.5

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

0.9

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

3.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.2

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.2

—

5.9

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

3.9

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.94

0.00

1.1

1.6

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.1

—

13.7

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

137.2

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

49.3

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.7

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

3.6

—

3.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

25.4

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

117.9

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_STRABMECH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_STRABMECH.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_STRABMECH – Mechanical strabismus

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Mechanical strabismus

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints