Melanocytic naevi of other and unspecified parts of face

CD2_BENIGN_MELANOCYTIC_FACE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.3&
  • Hospital discharge: ICD-9 2163A
  • Cause of death: ICD-10 D22.3&
  • Cause of death: ICD-9 2163A

2 out of 7 registries used, show all original rules.

2330

4. Check minimum number of events

None

2330

5. Include endpoints

None

2330

6. Filter based on genotype QC (FinnGen only)

2330

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) faciei

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 16215 10654 5504
Only index persons 15389 10225 5164
Unadjusted period prevalence (%)
Whole population 0.25 0.31 0.15
Only index persons 0.32 0.38 0.20
Median age at first event (years)
Whole population 44.36 44.13 44.75
Only index persons 44.23 43.97 44.75

-FinnGen-

Key figures

All Female Male
Number of individuals 2330 1635 695
Unadjusted period prevalence (%) 0.48 0.56 0.31
Median age at first event (years) 48.85 45.85 55.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2068
Matched controls
20680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
10681.7
323.0
1998
72
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
20.0
323.0
867
720
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.5
131.8
439
969
2163A
ICD-9 Finland
Benign neoplasm of skin, Skin of other and unspecified parts of face[KASVOJEN IHON BEN KASVAIN,NAEVUS PIGMENTOSUS]
+∞
77.6
74
*
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
8.8
74.1
165
201
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
9.7
68.4
144
159
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
5.0
68.2
236
520
L82
ICD-10 Finland
Seborrhoeic keratosis
2.8
53.8
403
1652
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
8.6
53.6
120
147
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.7
52.8
406
1688
L57.0
ICD-10 Finland
Actinic keratosis
3.6
51.8
260
804
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.4
51.3
197
480
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.8
50.6
234
675
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.9
44.6
197
545
TQW99
NOMESCO Finland
Other minor procedure on skin
4.4
41.7
160
388
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.9
36.2
158
431
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
42.8
34.1
42
10
S82
ICPC
Naevus/mole
2.4
33.5
306
1374
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.1
31.1
101
206
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
4.5
26.2
96
223
9733
FHL
Excision of skin change in operating room or anesthesia
7.0
25.6
64
94
S18
ICPC
Laceration/cut
1.7
25.0
804
5714
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
5.8
24.2
70
125
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
8.1
23.5
53
67
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.1
23.3
92
230
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.6
22.0
78
176
ZZR00
NOMESCO Finland
Flap of skin
5.2
21.9
69
137
DHB00
NOMESCO Finland
Excision of lesion of external nose
12.0
21.5
39
33
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.9
20.7
130
466
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
212.0
20.6
21
*
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
5.2
19.6
61
120
XQ848
NOMESCO Finland
Dermatological photography
4.0
19.4
78
199
SPAT1153
SPAT
Removal of sutures
1.6
19.3
586
4035
XQ845
NOMESCO Finland
Dermatoscopy
7.0
19.2
47
68
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.9
18.9
78
204
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
23.9
18.6
26
11
ZXC50
NOMESCO Finland
Cryotherapy
3.9
17.6
74
197
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
5.7
17.5
50
89
D22
ICD-10 Finland
Melanocytic naevi
2.6
15.9
115
451
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.6
15.4
69
195
I78.1
ICD-10 Finland
Naevus, non-neoplastic
3.6
14.6
65
183
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
36.3
14.4
18
5
D22.0
ICD-10 Finland
Melanocytic naevi of lip
27.4
14.3
19
7
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.8
14.1
59
158
ZXA00
NOMESCO Finland
Right side
1.6
13.8
475
3326
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
7.3
13.2
31
43
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
4.4
13.0
46
106
ZXA05
NOMESCO Finland
Left side
1.5
12.1
433
3051
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
8.2
12.0
26
32
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
6.9
11.6
28
41
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
4.4
11.1
39
90
F16
ICPC
Eyelid symptom/complaint
2.3
11.0
97
426
S21
ICPC
Skin texture symptom/complaint
1.7
10.8
218
1319
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
10.6
661
5183
J01DB01
ATC
cefalexin; oral
1.4
10.6
1584
14407
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
3.4
10.4
48
142
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
32.7
10.3
13
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
10.1
373
2638
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
40.2
10.0
12
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
9.9
426
3105
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
6.3
9.8
25
40
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
10.7
9.8
18
17
D22.1
ICD-10 Finland
Melanocytic naevi of eyelid, including canthus
7.8
9.6
21
27
S29
ICPC
Skin symptom/complaint other
1.6
9.4
294
1996
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
3.0
9.3
51
172
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
8.7
9.3
19
22
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
5.5
9.2
26
48
A02BC02
ATC
pantoprazole; systemic
1.3
9.0
1155
10085
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
36.8
9.0
11
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
8.7
304
2120
E0000UV
ATC
NA
1.3
8.7
715
5833
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
3.6
8.6
37
104
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
5.3
8.6
25
48
K03.64
ICD-10 Finland
Dental calculus supragingival
1.4
8.6
520
4035
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
4.4
8.5
29
66
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
2.6
8.5
61
241
WX110
NOMESCO Finland
Local anesthesy
1.3
8.4
1308
11693
DAB00
NOMESCO Finland
Excision of lesion of auricle
5.0
8.3
25
50
L72.1
ICD-10 Finland
Trichilemmal cyst
1.9
8.3
112
592
J01FA10
ATC
azithromycin; systemic
1.3
8.3
1116
9758
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
22.1
8.0
11
5
ZXC20
NOMESCO Finland
Use of chemical agents
3.3
7.9
38
118
ZXA10
NOMESCO Finland
Bilateral
1.5
7.9
309
2205
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.9
1339
12062
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
3.5
7.9
34
97
S04
ICPC
Lump/swelling localized
1.7
7.5
156
953
Z01.7
ICD-10 Finland
Laboratory examination
1.6
7.5
195
1264
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
6.5
7.4
18
28
L04AA01
ATC
[U] ciclosporin; systemic
3.5
7.4
32
92
Z94.0
ICD-10 Finland
Kidney transplant status
4.1
7.4
27
67
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.2
409
3121
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
4.3
7.2
25
59
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
4.8
7.1
22
46
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
3.4
7.1
32
95
ZQZ00
NOMESCO Finland
Treatment of several skin areas
7.0
7.0
16
23
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
6.9
679
5642
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.9
390
2977
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
6.8
261
1848
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.8
152
951
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
4.1
6.7
24
59
A98
ICPC
Health maint/preventive medicine
1.6
6.7
1947
18790
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.7
256
1817
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
4.9
6.7
20
41
R74
ICPC
Upper respiratory infection acute
1.3
6.7
537
4332
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.4
6.6
53
223
EMB10
NOMESCO Finland
Tonsillectomy
1.8
6.6
115
670
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.6
928
8069
127
Kela drug reimbursment
Transplant complication
3.2
6.5
32
102
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.4
6.5
422
3288
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
10.0
6.5
12
12
J05AB11
ATC
valaciclovir; oral
1.5
6.5
221
1527
J02AC01
ATC
fluconazole; systemic
1.3
6.5
757
6417
CBA10
NOMESCO Finland
Biopsy of eyelid
5.3
6.5
18
34
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
4.4
6.3
21
48
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
4.4
6.3
21
48
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
5.2
6.3
18
35
-
ICD-10 Finland
NA
2.5
6.3
45
181
C43.33
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face nodular
+∞
6.3
6
*
D03.30
ICD-10 Finland
Melanoma in situ on the lip
26.7
6.2
8
*
A02BC05
ATC
esomeprazole; systemic
1.3
6.2
686
5767
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
2.5
6.2
44
175
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
6.2
146
925
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.1
621
5160
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
7.7
6.1
13
17
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
3.7
6.1
24
65
WX002
NOMESCO Finland
Sedation and analgesia
1.4
6.0
310
2323
R4110
NOMESCO Finland
Physiotherapy
1.3
6.0
430
3399
L91.0
ICD-10 Finland
Hypertrophic scar
3.0
6.0
32
109

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1246
7845
2.26
80.03
2.7
2.0
—
—
—
0
0
444
2389
2.06
37.27
1.4
1.2
—
—
—
0
0
1857
16831
1.51
13.88
18.8
16.4
332.1
332.3
g/l
0.44
1840
16708
1142
9614
1.37
12.24
6.0
5.7
0.0
0.0
e9/l
0.97
991
8378
1138
9578
1.37
12.20
6.0
5.7
0.6
0.6
e9/l
1.10
988
8347
614
4670
1.43
12.06
4.2
3.7
92.2
92.7
%
0.21
600
4537
1174
9951
1.36
11.93
6.3
6.0
0.2
0.2
e9/l
0.12
1031
8816
1285
11100
1.35
11.27
9.0
8.8
3.8
4.0
e9/l
2.95
1111
9763
458
3339
1.46
11.19
3.1
3.5
247.0
452.1
ng/l
0.75
313
2389
2078
19509
1.60
11.16
15.6
14.3
139.7
139.6
mmol/l
1.00
2036
18995
2081
19565
1.60
10.85
15.8
14.4
3.9
3.9
mmol/l
3.74
2036
19016
1158
9889
1.34
10.75
6.0
5.7
2.0
1.9
e9/l
0.67
1027
8794
1976
18387
1.49
10.64
4.5
4.2
5.8
5.8
mmol/l
0.77
1847
16884
1938
17973
1.47
10.53
5.6
4.8
1.8
2.0
mu/l
0.86
1825
16652
2064
19394
1.56
10.50
13.9
12.9
21.6
22.1
mg/l
0.26
1627
15229
787
6359
1.36
10.48
6.0
5.7
—
—
—
0
0
1603
14404
1.36
10.42
7.9
7.2
76.7
76.6
u/l
0.04
1504
13571
689
5472
1.37
10.18
3.2
3.1
29.4
88.4
e6/l
2.36
524
4171
2251
21696
2.11
9.94
21.3
19.0
6.6
6.7
e9/l
0.37
2200
21131
2250
21689
2.09
9.84
21.2
18.9
30.1
30.2
pg
0.97
2228
21412
1581
14227
1.35
9.83
4.2
4.0
10.6
11.4
mm/h
2.02
1476
13202
804
6566
1.34
9.83
3.8
3.5
49.0
100.6
e6/l
2.51
560
4524
2250
21691
2.09
9.80
21.3
19.0
4.5
4.5
e12/l
1.62
2199
21136
2147
20418
1.66
9.73
16.0
14.7
73.7
73.6
umol/l
0.05
2147
20410
2250
21701
2.07
9.62
21.4
19.1
135.0
134.7
g/l
0.40
2226
21424
2249
21688
2.06
9.62
21.3
18.9
90.5
90.7
fl
1.47
2227
21414
1855
17154
1.40
9.46
5.6
5.3
38.6
39.1
mmol/mol
2.31
1761
15977
613
4833
1.36
9.35
6.7
6.5
—
—
—
0
0
411
3040
1.43
9.14
2.7
2.6
0.9
1.1
e6/l
0.77
224
1694
314
2208
1.49
9.09
1.5
1.7
—
—
—
0
0
2244
21675
1.96
8.73
21.4
19.0
256.7
256.8
e9/l
0.03
2199
21165
1051
9019
1.30
8.73
6.1
5.8
2.8
2.8
%
0.05
982
8413
301
2116
1.49
8.72
2.9
2.6
7.9
7.2
umol/l
0.21
258
1824
1020
8741
1.30
8.47
6.2
5.8
0.7
0.7
%
0.01
955
8164
1447
12981
1.30
8.46
3.8
3.5
—
—
—
0
0
2030
19168
1.46
8.40
5.0
4.5
2.8
2.8
mmol/l
0.21
1912
17795
1053
9069
1.29
8.39
6.3
6.0
8.4
8.4
%
0.05
992
8508
1682
15412
1.33
8.38
4.8
4.1
14.6
14.7
pmol/l
0.68
1558
14163
919
7776
1.30
8.38
4.7
4.6
36.3
35.9
g/l
1.55
856
7245
1471
13253
1.30
8.18
4.8
4.2
—
—
—
0
0
622
5005
1.33
8.10
3.1
3.0
0.4
0.4
e6/l
0.01
448
3750
381
2846
1.40
7.94
2.7
2.7
3.9
3.0
e6/l
0.61
197
1510
1037
8965
1.28
7.84
6.7
6.3
1.2
1.2
mmol/l
0.08
905
7575
1990
18770
1.41
7.82
4.3
4.1
1.5
1.5
mmol/l
0.20
1863
17450
864
7308
1.29
7.73
2.0
1.9
100.8
96.2
pmol/l
1.90
433
3786
1998
18882
1.41
7.55
4.4
4.1
4.7
4.7
mmol/l
0.41
1888
17662
1093
9543
1.27
7.52
6.2
5.9
10.9
10.9
umol/l
0.01
1029
9040
1408
12687
1.28
7.44
4.9
4.3
376.4
1998.7
e6/l
1.77
16
168
2141
20512
1.54
7.43
10.9
9.8
26.1
25.5
u/l
0.58
2083
19862
25
73
3.45
7.39
34.0
28.0
83.3
122.2
ug/l
4.78
25
63
2126
20343
1.51
7.36
12.7
12.1
—
—
—
0
0
249
1745
1.48
7.31
2.4
2.3
33.6
65.6
u/l
0.61
207
1486
299
2171
1.43
7.29
1.4
1.4
—
—
—
0
0
1072
9361
1.27
7.28
6.2
5.8
29.3
28.6
%
1.26
1007
8748
1921
18063
1.36
7.27
3.9
3.7
1.3
1.3
mmol/l
0.56
1788
16702
1057
9237
1.26
7.05
6.0
5.6
56.1
56.9
%
1.40
994
8666
1766
16434
1.31
6.97
17.7
15.6
13.5
13.6
%
1.18
1736
16083
195
1328
1.51
6.59
3.7
3.3
4.5
4.5
pmol/l
0.01
172
1182
643
5339
1.28
6.40
4.6
3.8
7.4
7.4
ph
0.46
78
1009
417
3268
1.34
6.35
2.9
2.9
2.4
2.4
mmol/l
0.51
347
2880
539
4379
1.30
6.34
4.1
3.5
—
—
—
0
0
597
4923
1.29
6.25
3.1
2.9
—
—
—
0
0
933
8122
1.25
6.17
6.0
5.6
1.2
1.2
mmol/l
0.05
858
7373
734
6227
1.26
6.06
3.3
3.3
2.4
2.4
mmol/l
0.14
633
5501
195
1353
1.48
6.03
4.5
3.6
82.8
84.5
ng/l
0.11
181
1181
679
5733
1.26
5.79
3.1
2.9
—
—
—
0
0
1916
18166
1.31
5.67
16.2
13.8
40.1
39.8
%
1.07
1480
13635
1074
9595
1.22
5.30
3.9
3.5
0.0
0.0
estimate
1.32
166
1769
590
4946
1.26
5.28
1.7
1.6
1.4
1.4
mmol/l
0.04
533
4193
19
59
3.24
5.17
2.0
3.0
—
—
—
0
0
272
2068
1.36
5.03
1.3
1.3
—
—
—
0
0
561
4701
1.25
5.00
2.6
2.5
2548.4
5168.0
umol/l
1.35
494
4132
1189
10769
1.21
5.00
4.3
4.5
6.5
6.6
mmol/l
1.07
1098
9989
465
3818
1.27
4.92
2.7
2.5
4.4
6.7
e6/l
3.50
401
3345
465
3826
1.27
4.83
5.4
4.8
2.3
2.6
ug/l
0.47
412
3410
249
1886
1.36
4.72
1.5
1.4
—
—
—
0
0
623
5319
1.23
4.65
2.0
2.1
139.8
208.6
u/l
2.54
590
5027
119
789
1.54
4.62
1.2
1.2
—
—
—
0
0
321
2536
1.31
4.57
2.3
2.3
82.8
117.1
ug/g
3.07
249
2002
833
7338
1.21
4.54
3.7
3.3
—
5.9
—
0
6
1054
9497
1.20
4.51
5.1
4.8
0.0
0.0
estimate
0.50
169
1810
93
589
1.60
4.42
1.2
1.2
—
—
—
0
0
286
2242
1.31
4.30
3.0
2.9
0.7
0.7
ug/l
0.24
183
1430
286
2243
1.31
4.29
5.4
5.4
1.1
1.0
mmol/l
0.71
268
2081
1047
9473
1.19
4.16
3.9
3.5
0.0
0.0
estimate
0.50
162
1780
1011
9125
1.19
4.12
4.2
4.0
—
—
—
0
0
1002
9037
1.19
4.12
3.2
2.8
101.2
103.2
ug/l
0.07
949
8402
161
1168
1.41
4.00
2.4
3.2
85.0
46.3
u/ml
0.55
155
1130
324
2624
1.27
3.80
1.2
1.2
—
—
—
0
0
629
5471
1.21
3.79
3.2
3.2
7.7
7.5
mmol/l
0.63
550
4641
205
1564
1.34
3.74
6.0
8.3
124.2
121.5
g/l
1.18
195
1507
126
892
1.44
3.61
2.8
2.7
0.1
0.3
e6/l
2.53
120
861
1400
13082
1.18
3.56
3.1
3.0
47.6
43.4
u/l
0.61
1320
12298
143
1040
1.40
3.53
2.5
2.1
11.6
12.2
nmol/l
0.37
135
919
125
889
1.43
3.50
7.1
10.5
—
—
—
0
0
87
576
1.53
3.48
1.5
1.3
8.5
11.1
u/l
1.49
71
465
202
1558
1.32
3.44
1.3
1.2
123.3
150.0
iu/ml
0.51
80
603
88
586
1.52
3.43
2.3
2.6
—
—
—
0
0
343
2835
1.25
3.39
3.2
3.2
0.8
0.8
mmol/l
0.03
321
2659
239
1895
1.29
3.33
5.5
7.6
0.8
1.1
mmol/l
0.49
177
1467
330
2727
1.24
3.27
1.4
1.3
734.2
503.0
titre
0.72
73
561
6
7
8.59
3.26
1.2
1.0
—
—
—
0
0
593
5196
1.19
3.24
3.8
3.9
12.9
8.7
mg/mmol
0.64
368
3246
106
743
1.45
3.23
1.4
1.3
240.1
229.0
miu/ml
0.11
49
358
26
123
2.13
3.20
6.4
6.5
—
—
—
0
0
54
327
1.67
3.15
1.3
1.4
3.0
4.3
ug/l
0.78
45
301
13
44
2.97
3.13
1.2
1.4
—
—
—
0
0
563
4934
1.19
3.05
3.3
3.2
198.2
353.3
mg/l
0.53
366
3072
480
4150
1.20
3.03
4.5
3.9
1.0
1.0
kg/l
0.17
62
606
117
847
1.40
3.01
1.1
1.1
—
—
—
0
0
496
4308
1.19
2.97
2.0
1.7
1.1
1.1
mg/l
0.14
377
3254
236
1900
1.27
2.93
5.6
7.5
5.1
5.1
kpa
0.27
224
1818
397
3393
1.20
2.83
1.3
1.3
5.1
10.6
u/ml
1.93
143
1368
45
268
1.69
2.82
1.7
1.5
—
—
—
0
0
150
1143
1.33
2.82
1.3
1.3
24.8
28.3
iu/l
0.64
135
972
235
1901
1.26
2.82
5.6
7.5
12.7
12.7
kpa
0.02
223
1820
36
202
1.79
2.77
5.3
4.4
273.1
98.6
u/ml
0.34
11
53
529
4653
1.18
2.72
1.3
1.3
0.7
1.5
u/ml
3.76
122
1251
79
546
1.46
2.65
2.0
1.9
2.8
5.0
iu/l
2.42
22
202
319
2692
1.21
2.60
2.6
2.0
30.1
29.5
s
0.71
308
2603
208
1676
1.26
2.59
5.9
8.1
95.9
95.8
%
0.17
196
1621
40
238
1.69
2.55
1.6
1.6
—
—
—
0
0
78
543
1.45
2.53
4.5
7.3
1.1
1.3
mmol/l
0.79
68
473
670
6034
1.15
2.52
2.4
2.3
—
—
—
0
0
457
4000
1.18
2.49
1.5
1.4
2.1
2.3
g/l
2.30
268
2494
107
792
1.37
2.46
1.3
1.3
1.3
1.1
u/ml
0.05
12
61
76
531
1.45
2.43
2.5
3.1
—
—
—
0
0
759
6913
1.15
2.42
7.2
8.3
1.2
1.2
inr
0.83
193
2062
23
117
1.98
2.40
1.2
1.2
—
—
—
0
0
32
182
1.77
2.40
1.1
1.1
—
—
—
0
0
9
27
3.34
2.39
1.3
1.3
127.2
84.1
ng/l
—
9
27
7
17
4.13
2.36
1.0
1.1
—
—
—
0
0
173
1381
1.27
2.35
7.9
8.1
—
—
—
0
0
483
4273
1.16
2.29
2.0
1.9
—
—
—
0
0
162
1288
1.28
2.28
1.5
1.4
—
—
—
0
0
122
935
1.32
2.26
2.5
2.3
—
—
—
0
0
404
3535
1.17
2.21
1.3
1.3
33.3
30.6
iu/ml
0.09
109
1114
638
5782
1.14
2.16
2.5
2.5
54.3
56.9
u/l
1.36
587
5355
19
94
2.03
2.16
3.3
2.9
—
—
—
0
0
115
882
1.32
2.14
2.2
1.8
—
—
—
0
0
36
221
1.64
2.09
1.3
1.4
—
—
—
0
0
56
382
1.48
2.07
5.0
8.8
10.6
11.3
mmol/l
0.89
49
346
132
1038
1.29
2.05
2.1
2.2
4327.9
5770.4
u/l
0.23
53
421
56
383
1.47
2.04
5.0
8.8
105.0
105.2
mmol/l
0.18
49
347
917
8528
1.12
2.04
8.8
8.9
0.0
0.0
e9/l
0.01
728
6996
175
1426
1.25
2.03
6.9
7.2
10.1
9.1
mmol/l
0.87
161
1365
223
1867
1.22
2.01
2.7
2.7
1.7
1.8
%
0.70
201
1660
23
402
0.57
2.00
3.9
3.7
43.5
24.7
mg/l
0.68
16
261
39
251
1.56
1.90
1.3
1.3
—
0.4
nmol/l
—
0
15
50
340
1.48
1.90
1.2
1.2
—
—
—
0
0
18
92
1.96
1.90
2.4
2.3
18.9
105.0
ug/l
0.49
18
81
207
1734
1.21
1.87
3.3
4.1
28.9
21.5
ug/l
0.12
156
1383
111
866
1.30
1.86
6.9
9.4
24.0
24.3
mmol/l
0.50
102
813
27
159
1.71
1.85
2.5
3.1
17.8
38.9
mg/l
0.73
21
112
458
4101
1.15
1.84
1.6
1.5
20.9
20.9
nmol/l
0.01
405
3523
78
580
1.36
1.82
2.0
1.6
0.2
0.2
g/l
0.53
73
549
23
130
1.78
1.81
1.0
1.1
2.0
11.1
iu/ml
—
8
36
243
2073
1.19
1.81
22.6
22.7
1.2
1.3
inr
0.31
38
297
117
1470
0.79
1.80
2.9
3.4
1.2
1.2
mmol/l
0.36
101
1263
15
287
0.52
1.79
6.8
5.5
412.3
368.2
umol/l
0.69
15
247
25
146
1.72
1.77
1.2
1.2
—
—
—
0
0
9
36
2.51
1.74
1.0
1.1
—
—
—
0
0
9
36
2.51
1.74
1.2
1.7
—
—
—
0
0
163
1345
1.23
1.72
2.7
2.8
103.2
181.8
ng/l
6.37
147
1214
30
186
1.62
1.72
3.5
3.0
2.4
32.9
nmol/l
0.52
30
181
78
589
1.34
1.67
3.0
3.6
321.8
2337.6
u/ml
0.63
63
507
21
119
1.77
1.66
2.7
2.1
0.2
0.2
e9/l
0.64
16
104
43
293
1.48
1.65
1.4
1.4
—
—
—
0
0
163
1355
1.22
1.62
2.4
2.4
40.1
21.5
au/ml
—
9
86
160
1328
1.22
1.61
1.3
1.3
166.3
198.1
u/ml
0.40
155
1220
47
328
1.44
1.61
1.7
1.8
—
—
—
0
0
503
4572
1.13
1.60
2.5
2.2
—
—
—
0
0
23
136
1.70
1.59
1.2
1.3
—
—
—
0
0
398
3571
1.14
1.56
2.7
2.6
536.3
541.8
mosm/kgh2o
0.20
347
3039
35
232
1.52
1.54
1.3
1.3
—
—
—
0
0
21
123
1.71
1.51
2.7
2.1
480.3
575.0
e6/l
0.35
16
104
16
86
1.87
1.50
3.7
3.1
—
—
—
0
0
51
367
1.40
1.49
1.1
1.1
2.8
2.9
u/ml
0.00
17
91
138
1142
1.22
1.46
1.4
1.2
—
—
—
0
0
31
462
0.67
1.45
3.5
3.7
7.4
7.4
ph
0.66
31
370
11
52
2.12
1.44
1.5
1.9
146.0
167.7
e6/l
—
5
26
60
447
1.35
1.44
1.2
1.1
0.7
1.5
u/ml
0.82
30
174
61
456
1.35
1.43
1.1
1.2
—
6.2
—
0
8
43
304
1.42
1.40
1.9
1.5
0.9
0.7
g/l
0.29
37
228
52
381
1.37
1.39
1.2
1.1
0.9
1.5
u/ml
0.38
29
157
33
222
1.49
1.38
1.3
1.3
—
—
nmol/l
—
0
0
11
53
2.08
1.38
1.2
1.5
—
—
—
0
0
292
2591
1.15
1.37
2.8
2.3
2.4
2.4
g/l
0.44
276
2396
151
1272
1.20
1.35
1.3
1.2
—
—
—
0
0
237
2074
1.16
1.35
6.3
6.5
104.7
104.4
mmol/l
0.43
232
2028
191
1645
1.18
1.33
1.1
1.2
—
—
—
0
0
53
393
1.36
1.33
1.2
1.1
7.0
5.3
u/ml
0.29
36
204
12
61
1.97
1.32
1.3
1.2
—
—
—
0
0
275
2439
1.14
1.30
1.8
1.6
—
—
—
0
0
164
1398
1.19
1.29
2.0
2.3
5.0
6.8
ug/l
1.06
136
1233
207
1799
1.17
1.29
2.3
2.1
378.1
377.4
nmol/l
0.02
191
1650
160
1363
1.19
1.28
2.7
2.6
68.4
71.2
e9/l
0.42
119
1029
32
220
1.46
1.23
1.4
1.4
311.4
291.3
pmol/l
0.21
25
171
32
220
1.46
1.23
2.4
2.3
—
—
—
0
0
21
131
1.61
1.23
1.5
2.0
10.1
13.6
%
1.24
12
66
128
1074
1.20
1.21
3.8
5.4
—
—
—
0
0
485
4470
1.11
1.21
3.8
4.3
—
—
—
0
0
5
19
2.63
1.21
1.4
1.2
—
—
—
0
0
8
37
2.17
1.21
1.0
1.1
—
—
—
0
0
104
856
1.22
1.20
1.9
1.6
317.2
301.6
mu/l
0.21
96
768
34
239
1.43
1.18
1.7
1.5
21.8
45.7
mu/l
1.84
29
216
124
1041
1.20
1.18
5.3
7.3
24.7
24.5
mmol/l
0.24
114
973
44
324
1.36
1.18
1.5
1.5
—
—
—
0
0
123
1032
1.20
1.18
7.0
9.0
94.1
94.0
%
0.09
123
1026
20
125
1.61
1.17
1.1
1.0
—
—
—
0
0
51
385
1.33
1.17
1.5
1.5
0.3
0.4
nmol/l
0.23
43
301
123
1037
1.20
1.13
6.9
8.9
0.7
0.7
%
0.27
123
1031
25
167
1.50
1.12
2.6
2.1
1.2
1.2
e9/l
—
10
102
42
310
1.36
1.12
1.2
1.2
—
—
—
0
0
28
192
1.46
1.11
1.4
1.4
—
—
—
0
0
13
73
1.79
1.10
1.5
2.0
6.5
10.9
%
1.12
13
68
37
268
1.39
1.10
1.1
1.0
0.8
0.4
u/ml
0.25
12
61
7
31
2.26
1.10
1.9
1.2
5.3
5.7
nmol/l
—
7
31
7
31
2.26
1.10
1.1
1.2
—
—
—
0
0
60
469
1.29
1.09
1.1
1.1
—
—
—
0
0
23
152
1.52
1.09
1.7
1.5
0.8
1.0
g/l
2.05
23
152
312
2826
1.12
1.09
2.8
2.3
76.8
13.5
umol/l
0.49
299
2610
497
4613
1.10
1.08
4.2
4.1
—
—
—
0
0
59
749
0.78
1.08
3.9
3.6
—
—
—
0
0
48
365
1.32
1.07
5.6
2.7
—
—
—
0
0
148
1276
1.17
1.06
3.0
2.8
—
—
—
0
0
352
3846
0.90
1.06
1.6
1.6
431.5
29273275.7
pmol/l
3.29
302
3218
259
2325
1.13
1.05
1.7
1.8
—
—
—
0
0
39
289
1.36
1.03
1.1
1.1
5.3
5.9
u/ml
0.07
20
116
89
735
1.22
1.03
2.4
1.9
1.2
1.5
g/l
2.51
75
642
149
1293
1.16
1.00
1.4
1.4
—
—
—
0
0
93
775
1.21
0.99
1.8
1.7
—
—
—
0
0
32
436
0.73
0.99
4.0
4.3
—
—
—
0
0
130
1118
1.17
0.98
2.0
1.8
1.9
1.4
g/l
0.50
118
1027
0
29
0.00
0.97
0.0
1.1
—
1.7
—
0
18
21
140
1.50
0.97
2.4
1.9
12.3
11.1
%
0.72
21
140
20
132
1.52
0.97
2.5
2.3
693.9
629.9
ml
0.37
15
88
183
1617
1.14
0.96
1.3
1.4
—
—
—
0
0
0
32
0.00
0.95
0.0
1.8
—
—
—
0
0
45
578
0.77
0.94
1.4
1.5
—
—
—
0
0
284
2584
1.11
0.93
2.0
2.0
—
—
—
0
0
45
347
1.30
0.93
1.5
1.4
19.1
25.6
u/l
0.87
38
289
12
70
1.72
0.92
2.7
2.1
1.4
1.2
ug/l
0.24
12
65
21
142
1.48
0.92
1.1
1.1
—
—
—
0
0
48
376
1.28
0.90
1.5
1.4
—
—
—
0
0
21
143
1.47
0.89
1.9
2.1
—
—
—
0
0
263
2392
1.11
0.88
3.0
2.4
22.5
23.2
%
0.37
222
2046
120
1042
1.16
0.83
7.1
8.8
1.3
1.4
%
0.10
120
1036
26
188
1.39
0.83
1.3
1.4
3.1
2.9
g/l
0.22
21
127
39
301
1.30
0.83
1.1
1.0
2.0
2.2
u/ml
0.10
22
146
86
727
1.19
0.82
3.5
2.1
21.4
21.0
s
0.35
69
629
22
155
1.42
0.81
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
1371.8
—
0
16
46
574
0.80
0.79
1.4
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
1.5
—
0
16
0
26
0.00
0.78
0.0
2.1
—
3.1
—
0
10
185
1663
1.12
0.78
2.1
2.2
0.2
0.2
g/l
0.43
171
1562
12
74
1.62
0.78
3.1
2.9
—
—
—
0
0
21
148
1.42
0.77
1.3
1.1
70.0
140.0
titre
—
6
29
502
4737
1.08
0.76
2.4
2.1
2.8
2.9
mg/l
0.45
443
4033
92
790
1.17
0.75
1.1
1.1
—
—
—
0
0
48
592
0.81
0.75
1.4
1.5
—
—
—
0
0
11
67
1.64
0.75
1.5
2.5
—
—
—
0
0
80
681
1.18
0.73
4.1
6.1
1.7
1.6
%
0.49
73
637
18
125
1.44
0.72
3.3
2.2
663.2
787.7
e6/l
—
9
50
80
682
1.18
0.72
4.2
6.1
0.9
0.9
%
0.00
73
640
40
317
1.27
0.72
1.1
1.1
0.7
4.8
u/ml
3.28
19
118
12
76
1.58
0.71
1.3
1.6
12.5
14.0
pmol/l
0.64
12
63
7
40
1.75
0.71
1.1
1.0
—
—
—
0
0
19
134
1.42
0.71
1.1
1.3
43.5
30.6
nmol/l
0.89
14
114
5
26
1.93
0.70
1.0
1.5
7.1
464711.1
nmol/l
—
5
17
53
436
1.22
0.70
1.5
1.4
24.4
32.6
e6/l
0.20
41
339
53
436
1.22
0.70
1.6
1.5
143.7
1603.8
e6/l
1.48
42
356
33
257
1.29
0.68
1.2
1.2
—
—
—
0
0
26
341
0.76
0.68
2.6
2.4
16.3
16.4
%
0.02
18
170
160
1443
1.12
0.66
3.9
3.4
—
—
—
0
0
13
191
0.68
0.66
2.8
2.5
—
—
—
0
0
5
28
1.79
0.66
1.0
1.0
—
—
—
0
0
16
111
1.44
0.66
1.9
1.4
18.0
25.1
umol/l
0.49
16
105
50
603
0.83
0.65
15.6
8.9
—
—
—
0
0
167
1512
1.11
0.65
4.8
3.5
1.5
1.9
mmol/l
0.77
133
1217
40
322
1.25
0.65
1.2
1.2
4.7
4.6
u/ml
0.01
19
138
49
405
1.21
0.63
2.0
2.8
24.4
25.0
mmol/l
0.62
42
354
13
87
1.50
0.63
1.7
3.4
7.4
7.4
ph
—
6
27
11
164
0.67
0.61
1.1
1.3
0.0
0.7
u/ml
—
6
65
152
1676
0.90
0.61
3.6
3.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
5.7
—
0
11
376
3551
1.07
0.58
1.8
1.6
—
—
—
0
0
13
89
1.46
0.58
1.5
1.2
—
—
—
0
0
43
355
1.22
0.57
1.5
1.7
—
—
—
0
0
5
86
0.58
0.56
1.6
2.7
2082.8
1951.5
ml
—
5
76
40
329
1.22
0.56
2.1
2.5
—
—
—
0
0
5
89
0.56
0.56
1.4
1.6
—
—
—
0
0
91
804
1.14
0.55
6.3
3.7
24.1
24.1
mmol/l
0.10
83
731
6
38
1.58
0.54
1.3
1.2
—
—
—
0
0
9
60
1.50
0.54
3.2
3.2
—
—
—
0
0
42
349
1.21
0.54
1.4
1.4
102.3
110.4
u/ml
—
7
61
333
3150
1.07
0.50
1.6
1.7
1115.4
1191.4
nmol/l
0.86
244
2400
92
1029
0.89
0.50
3.4
3.4
7.4
7.4
ph
0.83
13
127
12
84
1.43
0.49
1.3
1.1
155.7
190.4
iu/ml
0.36
12
84
31
377
0.82
0.48
3.5
3.9
5.0
5.0
kpa
0.31
31
371
482
4619
1.05
0.48
2.8
2.9
1117.3
1231.0
ng/l
0.27
388
3864
31
376
0.82
0.47
3.5
4.0
8.9
8.7
kpa
0.38
31
370
31
376
0.82
0.47
3.4
3.9
2.8
2.6
mmol/l
0.18
19
255
7
48
1.46
0.46
4.6
4.7
—
—
—
0
0
163
1762
0.92
0.46
4.6
3.9
—
—
—
0
0
28
229
1.23
0.44
1.0
1.2
—
—
—
0
0
94
1038
0.90
0.43
3.4
3.4
5.1
5.2
kpa
0.83
85
971
5
31
1.61
0.43
1.4
1.0
—
—
—
0
0
5
31
1.61
0.43
1.4
1.0
—
—
—
0
0
5
31
1.61
0.43
1.4
1.0
—
—
—
0
0
5
32
1.56
0.42
1.6
1.3
30.2
21.8
%
—
5
24
164
1525
1.08
0.42
4.9
3.5
5.8
5.8
kpa
0.04
156
1480
0
15
0.00
0.41
0.0
1.1
—
190.7
—
0
7
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
59
520
1.14
0.41
1.3
1.2
77.0
90.2
titre
—
10
40
14
105
1.34
0.41
1.5
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
8
60
1.33
0.40
1.6
1.2
—
—
—
0
0
262
2483
1.06
0.40
1.6
1.7
—
—
—
0
0
35
411
0.85
0.40
1.2
1.2
—
—
—
0
0
110
1008
1.10
0.39
6.4
7.1
24.5
24.9
mmol/l
0.60
110
1001
12
160
0.75
0.39
1.1
1.1
—
—
—
0
0
17
215
0.79
0.39
2.9
2.7
—
—
—
0
0
16
124
1.29
0.38
1.1
1.1
—
—
—
0
0
42
364
1.16
0.37
1.9
3.0
8.5
8.2
kpa
0.55
37
336
8
116
0.69
0.37
1.3
1.2
—
11.1
—
0
13
9
70
1.29
0.36
4.0
3.8
88.2
64.6
mg/l
—
9
50
6
42
1.43
0.35
1.8
1.8
—
—
—
0
0
6
44
1.36
0.34
1.0
1.1
—
—
—
0
0
153
1434
1.07
0.34
2.7
2.7
10.0
10.6
g/l
0.91
141
1310
31
361
0.86
0.33
1.2
1.1
—
—
—
0
0
134
1433
0.93
0.33
3.4
3.8
0.5
0.6
%
0.18
25
306
697
7140
0.97
0.32
2.5
2.6
—
—
—
0
0
132
1410
0.93
0.32
3.8
4.1
0.0
0.6
%
0.90
29
323
31
359
0.86
0.32
1.2
1.1
—
—
—
0
0
20
165
1.21
0.31
1.4
1.5
36.3
35.4
%
0.03
12
103
24
202
1.19
0.31
1.2
1.6
—
—
—
0
0
33
286
1.16
0.31
1.9
2.5
—
—
—
0
0
33
287
1.15
0.30
2.3
1.9
—
4.2
—
0
6
169
1599
1.06
0.30
1.6
1.4
—
—
—
0
0
42
373
1.13
0.29
2.1
2.2
127.9
130.0
g/l
0.25
32
279
34
387
0.88
0.28
3.1
2.5
—
—
—
0
0
16
130
1.23
0.28
1.5
1.3
—
1.5
—
0
7
13
162
0.80
0.28
1.2
1.2
39.6
40.3
mg/l
0.02
13
135
13
162
0.80
0.28
1.3
1.5
—
—
—
0
0
46
512
0.90
0.28
1.2
1.3
—
—
—
0
0
8
63
1.27
0.27
1.8
1.9
—
—
—
0
0
43
384
1.12
0.27
1.3
1.3
—
—
—
0
0
9
120
0.75
0.27
20.3
13.8
975.4
874.5
nmol/l
—
9
115
27
311
0.87
0.27
3.4
3.2
0.8
0.8
nmol/l
0.01
19
249
50
552
0.90
0.26
1.5
1.3
—
—
—
0
0
15
182
0.82
0.26
1.0
1.0
—
—
—
0
0
5
72
0.69
0.26
2.2
2.3
126.0
150.4
nmol/l
—
5
65
142
1498
0.94
0.25
3.7
4.0
0.0
0.1
%
9.41
33
380
120
1272
0.94
0.25
1.8
1.7
—
—
—
0
0
33
293
1.13
0.24
1.3
1.5
—
—
—
0
0
14
115
1.22
0.23
1.1
1.1
—
—
—
0
0
118
1116
1.06
0.23
2.7
2.5
—
—
—
0
0
19
162
1.17
0.23
3.6
3.1
59.8
54.9
%
—
8
115
14
168
0.83
0.22
3.0
2.7
—
—
—
0
0
32
358
0.89
0.22
3.4
3.4
—
—
—
0
0
7
95
0.74
0.22
1.7
2.5
—
—
—
0
0
27
305
0.88
0.22
1.6
2.2
4.4
4.6
umol/l
0.07
22
221
87
926
0.94
0.22
3.4
3.3
—
—
—
0
0
28
248
1.13
0.21
1.2
1.3
—
70.5
—
0
13
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.1
—
0
7
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
12
98
1.23
0.21
1.7
1.4
—
—
—
0
0
55
595
0.92
0.21
3.3
3.7
1.2
1.4
mmol/l
0.66
55
587
5
43
1.16
0.21
1.2
2.8
—
—
—
0
0
11
89
1.24
0.21
1.5
1.9
—
—
—
0
0
11
89
1.24
0.21
1.1
1.1
1443.3
1640.7
miu/ml
0.23
11
89
0
13
0.00
0.21
0.0
1.1
—
0.1
—
0
6
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
10.9
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
516
5052
1.03
0.21
3.5
3.6
—
—
—
0
0
14
117
1.20
0.20
1.5
1.2
—
—
—
0
0
132
1259
1.05
0.20
3.7
2.9
4.7
4.6
kpa
0.22
125
1219
0
14
0.00
0.20
0.0
1.0
—
0.1
—
0
5
13
155
0.84
0.20
1.2
1.4
9.8
11.6
umol/l
0.53
13
146
13
155
0.84
0.20
1.2
1.1
271.6
244.2
mg/l
0.17
13
134
6
49
1.23
0.20
1.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.0
1.1
—
—
—
0
0
50
461
1.09
0.20
3.0
2.0
—
—
—
0
0
6
50
1.20
0.19
1.0
1.0
—
—
—
0
0
42
385
1.09
0.19
3.2
3.7
56.3
57.2
%
0.23
42
385
69
647
1.07
0.19
3.6
4.5
—
—
—
0
0
35
318
1.10
0.18
1.1
1.2
—
—
—
0
0
518
5081
1.03
0.18
4.6
3.8
0.0
0.0
estimate
1.28
165
1774
7
60
1.17
0.17
1.3
1.4
—
—
—
0
0
151
1569
0.96
0.17
3.5
4.0
0.7
0.9
%
0.48
37
415
30
272
1.10
0.17
1.5
1.5
—
—
—
0
0
33
301
1.10
0.17
1.6
1.3
62.1
64.6
mmol/l
0.13
26
246
36
330
1.09
0.17
1.2
1.1
—
—
—
0
0
44
408
1.08
0.16
2.8
2.4
49.2
93.0
ug/min
1.23
30
253
21
187
1.12
0.15
1.9
3.0
—
—
—
0
0
19
168
1.13
0.15
1.4
2.2
—
—
—
0
0
25
226
1.11
0.15
1.2
1.1
—
—
—
0
0
14
121
1.16
0.15
1.0
1.0
0.1
4.6
u/ml
—
5
18
17
151
1.13
0.13
1.0
1.2
—
—
—
0
0
40
374
1.07
0.13
3.3
3.4
4.1
4.1
e9/l
0.09
40
374
672
6643
1.02
0.12
3.3
3.4
23.5
45.4
ng/l
2.49
389
4182
39
365
1.07
0.12
2.6
3.9
—
—
—
0
0
16
179
0.89
0.12
1.4
1.2
—
—
—
0
0
80
767
1.04
0.12
4.1
2.5
1.4
1.2
%
0.37
80
762
207
2118
0.98
0.11
1.4
1.3
—
—
—
0
0
18
199
0.90
0.11
1.4
1.3
—
—
—
0
0
233
2281
1.02
0.11
1.4
1.4
—
—
—
0
0
38
403
0.94
0.10
1.4
1.5
—
—
—
0
0
16
177
0.90
0.10
1.1
1.4
23578.0
115318.7
e6/l
—
9
120
17
154
1.10
0.10
1.1
1.0
—
—
—
0
0
86
890
0.97
0.10
2.0
2.0
—
—
—
0
0
51
487
1.05
0.09
3.0
3.6
153.0
68.2
mg/l
0.42
37
401
22
237
0.93
0.09
1.4
1.2
—
—
—
0
0
65
626
1.04
0.09
2.7
2.7
—
—
—
0
0
51
489
1.04
0.08
3.0
3.6
28.1
75.4
mg/l
1.04
37
404
5
61
0.82
0.08
1.0
1.0
—
—
—
0
0
5
61
0.82
0.08
1.0
1.4
—
—
—
0
0
85
825
1.03
0.08
1.9
2.0
—
—
—
0
0
7
65
1.08
0.08
1.4
1.3
—
—
—
0
0
46
441
1.04
0.07
1.3
1.7
22661.3
11661.0
e6/l
0.31
31
323
6
75
0.80
0.07
1.0
1.0
—
—
—
0
0
138
1352
1.02
0.07
2.8
2.7
67.4
66.7
g/l
0.61
129
1235
8
77
1.04
0.07
1.0
1.1
—
—
—
0
0
7
81
0.86
0.07
1.1
1.7
—
—
—
0
0
7
84
0.83
0.07
3.0
1.9
—
—
—
0
0
64
621
1.03
0.06
1.9
2.0
1.0
1.7
ug/l
0.60
54
542
13
119
1.09
0.06
2.1
3.1
—
—
—
0
0
86
880
0.98
0.06
2.0
1.9
—
—
—
0
0
62
603
1.03
0.05
3.1
3.3
0.2
0.3
g/l
0.44
31
240
10
90
1.11
0.05
1.1
1.8
—
—
—
0
0
15
139
1.08
0.05
1.5
1.4
—
—
—
0
0
34
327
1.04
0.05
1.1
1.1
—
—
—
0
0
12
130
0.92
0.04
1.2
1.2
—
—
—
0
0
569
5721
0.99
0.04
1.5
1.5
—
—
—
0
0
22
209
1.05
0.04
1.3
1.5
—
—
—
0
0
22
209
1.05
0.04
1.3
1.5
—
—
—
0
0
22
209
1.05
0.04
1.3
1.5
—
—
—
0
0
22
209
1.05
0.04
1.3
1.5
—
—
—
0
0
29
302
0.96
0.04
1.0
1.1
82.8
1804.4
iu/ml
—
5
74
38
368
1.03
0.04
1.5
2.1
0.7
0.9
nmol/l
0.91
32
305
34
351
0.97
0.03
2.5
3.1
30.2
34.7
umol/l
0.79
26
298
530
5281
1.00
0.02
3.1
3.2
—
—
—
0
0
20
192
1.04
0.02
1.2
1.5
—
—
—
0
0
11
103
1.07
0.02
1.0
1.0
678.4
704.6
ng/l
—
5
69
11
117
0.94
0.01
1.1
1.2
—
—
—
0
0
69
699
0.99
0.01
2.1
2.0
—
—
—
0
0
89
899
0.99
0.01
1.9
2.0
—
—
—
0
0
53
523
1.01
0.01
1.4
1.4
315.5
297.1
ug/g
0.23
29
282
11
104
1.06
0.01
1.0
1.0
343.0
320.1
ng/l
—
5
71
19
184
1.03
0.00
1.0
1.1
—
—
—
0
0
33
336
0.98
0.00
1.5
1.6
—
—
—
0
0
89
896
0.99
0.00
1.9
2.0
—
—
—
0
0
11
105
1.05
0.00
1.2
1.4
149.9
136.0
nmol/l
0.67
11
105
15
155
0.97
0.00
1.0
1.1
422.1
399.9
nmol/l
0.18
15
141
14
139
1.01
0.00
1.2
2.0
3.5
3.8
mg/l
0.16
14
132
15
151
0.99
0.00
1.4
1.5
—
—
—
0
0
22
219
1.00
0.00
1.5
1.2
—
—
—
0
0
26
261
1.00
0.00
3.7
3.4
1.8
1.3
%
0.25
18
213
68
675
1.01
0.00
1.4
1.2
—
—
—
0
0
19
194
0.98
0.00
1.3
2.3
—
—
—
0
0
38
384
0.99
0.00
1.4
1.2
201.0
260.1
u/ml
0.96
22
246
53
526
1.01
0.00
1.3
1.2
2.2
2.3
u/ml
—
5
59
22
222
0.99
0.00
2.1
3.0
—
—
—
0
0
136
1357
1.00
0.00
3.0
2.8
4.0
4.1
e9/l
0.16
110
1090
12
117
1.03
0.00
1.1
1.0
—
—
—
0
0
22
223
0.99
0.00
1.3
1.6
58.6
57.8
%
0.02
11
147
24
237
1.01
0.00
2.9
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
8
81
0.99
0.00
1.6
2.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
116.0
—
0
5
5
49
1.02
0.00
2.0
1.1
338.2
299.1
pmol/l
—
5
36
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
55
550
1.00
0.00
1.1
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
0.00
1.5
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
19
190
1.00
0.00
6.8
3.7
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
0.00
2.2
1.6
—
—
—
0
0
13
130
1.00
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
1.2
1.3
47.3
48.7
%
—
5
50
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
64.8
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
1234.0
—
0
6
0
7
0.00
0.00
0.0
1.0
—
3.1
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
0.00
1.0
1.2
—
—
—
0
0
9
91
0.99
0.00
1.7
2.0
1.2
2.3
ug/l
—
9
76

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_FACE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_FACE 0.859 [0.77, 0.96] 0.009
Birth year 0.997 [0.99, 1.01] 0.513

During the follow-up period (1.1.1998 — 31.12.2019), 755 out of 8978 females with CD2_BENIGN_MELANOCYTIC_FACE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_FACE 0.856 [0.76, 0.97] 0.013
Birth year 0.993 [0.98, 1.0] 0.108

During the follow-up period (1.1.1998 — 31.12.2019), 590 out of 4616 males with CD2_BENIGN_MELANOCYTIC_FACE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_FACE.

N-year risk Females Males
1 0.072% 0.191%
5 0.436% 1.109%
10 1.176% 2.921%
15 2.395% 5.773%
20 4.597% 9.912%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_FACE – Melanocytic naevi of other and unspecified parts of face

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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