Melanocytic naevi of other and unspecified parts of face

CD2_BENIGN_MELANOCYTIC_FACE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.3&
  • Hospital discharge: ICD-9 2163A
  • Cause of death: ICD-10 D22.3&
  • Cause of death: ICD-9 2163A

2 out of 7 registries used, show all original rules.

2416

4. Check minimum number of events

None

2416

5. Include endpoints

None

2416

6. Filter based on genotype QC (FinnGen only)

2333

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) faciei

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 16215 10654 5504
Only index persons 15389 10225 5164
Unadjusted period prevalence (%)
Whole population 0.25 0.31 0.15
Only index persons 0.32 0.38 0.20
Median age at first event (years)
Whole population 44.36 44.13 44.75
Only index persons 44.23 43.97 44.75

-FinnGen-

Key figures

All Female Male
Number of individuals 2333 1637 696
Unadjusted period prevalence (%) 0.50 0.58 0.32
Median age at first event (years) 49.27 46.06 56.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2416
Matched controls
24160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
18.8
307.7
1033
921
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
5482.3
307.7
2336
128
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.6
233.6
519
1125
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
9.1
130.1
164
192
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
8.8
121.4
156
187
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
7.1
117.7
183
274
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
4.3
103.9
299
777
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.3
93.9
260
655
2163A
ICD-9 Finland
Benign neoplasm of skin, Skin of other and unspecified parts of face[KASVOJEN IHON BEN KASVAIN,NAEVUS PIGMENTOSUS]
+∞
88.1
84
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.7
83.3
285
834
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.9
83.2
261
719
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.6
81.7
634
2948
L57.0
ICD-10 Finland
Actinic keratosis
3.3
81.0
336
1113
L82
ICD-10 Finland
Seborrhoeic keratosis
2.6
74.3
549
2481
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.6
62.3
121
225
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.7
62.1
213
621
TQW99
NOMESCO Finland
Other minor procedure on skin
3.8
59.4
189
523
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
18.0
56.8
46
26
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
5.5
50.2
98
183
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
8.5
47.6
62
75
9733
FHL
Excision of skin change in operating room or anesthesia
6.7
46.9
75
115
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.5
41.3
102
233
XQ845
NOMESCO Finland
Dermatoscopy
5.6
40.9
79
146
S82
ICPC
Naevus/mole
2.2
39.4
393
1976
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.8
36.1
114
313
ZZR00
NOMESCO Finland
Flap of skin
4.6
35.1
84
187
XQ848
NOMESCO Finland
Dermatological photography
3.8
34.7
107
289
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.5
34.5
85
194
DHB00
NOMESCO Finland
Excision of lesion of external nose
7.1
33.9
51
73
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
3.6
33.9
113
322
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
5.0
33.4
72
147
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
4.9
32.9
72
149
S18
ICPC
Laceration/cut
1.7
32.8
1063
7700
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.0
32.5
93
238
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.9
32.2
158
569
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
5.0
30.5
66
135
Z2221
NOMESCO Finland
Medical doctor
1.7
28.2
686
4565
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
7.2
27.2
40
56
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.8
26.9
83
224
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
10.1
26.5
30
30
ZXC50
NOMESCO Finland
Cryotherapy
3.5
25.8
90
264
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
27.3
25.8
35
13
I78.1
ICD-10 Finland
Naevus, non-neoplastic
3.7
24.4
78
216
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
6.9
23.4
36
53
D22
ICD-10 Finland
Melanocytic naevi
2.4
22.4
162
706
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
4.2
21.8
58
141
SPAT1153
SPAT
Removal of sutures
1.6
21.6
695
4902
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
3.8
20.1
61
163
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
20.1
854
6385
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
28.0
18.7
25
9
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
31.7
17.0
22
7
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
6.1
16.9
29
48
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
6.1
16.4
28
46
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
15.2
767
5859
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
3.0
15.2
67
228
ZXA00
NOMESCO Finland
Right side
1.5
14.8
541
3875
F16
ICPC
Eyelid symptom/complaint
2.2
14.7
130
617
ZXA05
NOMESCO Finland
Left side
1.5
14.6
500
3532
ZXE00
NOMESCO Finland
One hour or less
1.4
14.5
860
6755
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
14.5
498
3518
S21
ICPC
Skin texture symptom/complaint
1.7
14.4
313
1985
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
3.6
14.0
45
126
L72.1
ICD-10 Finland
Trichilemmal cyst
2.0
13.9
158
824
Z94.0
ICD-10 Finland
Kidney transplant status
4.5
13.8
33
74
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
13.7
551
4018
127
Kela drug reimbursment
Transplant complication
3.8
13.5
41
110
D22.1
ICD-10 Finland
Melanocytic naevi of eyelid, including canthus
5.9
13.5
24
41
L04AA01
ATC
[U] ciclosporin
3.8
13.4
40
106
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
13.3
830
6554
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
13.2
561
4132
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
3.7
13.1
40
108
J01DB01
ATC
cefalexin; oral
1.5
13.0
1910
17385
DAB00
NOMESCO Finland
Excision of lesion of auricle
4.7
12.8
29
62
S77
ICPC
Malignant neoplasm of skin
4.2
12.7
33
79
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
3.7
12.5
39
107
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
4.6
12.4
29
64
S29
ICPC
Skin symptom/complaint other
1.5
12.1
409
2868
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
16.0
12.1
19
12
B03XA01
ATC
erythropoietin; parenteral
5.0
11.9
25
50
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
11.9
621
4734
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
4.5
11.4
27
60
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
5.2
11.3
23
45
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
11.3
191
1132
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
2.6
11.2
62
239
D22.0
ICD-10 Finland
Melanocytic naevi of lip
10.1
11.0
21
21
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
9.2
11.0
22
24
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
4.7
10.9
25
54
R42
ICD-10 Finland
Dizziness and giddiness
1.5
10.9
459
3359
Z71.8
ICD-10 Finland
Other specified counselling
1.4
10.8
687
5402
ZXD20
NOMESCO Finland
Day surgery
1.6
10.8
280
1852
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
17.9
10.7
16
9
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.5
10.7
67
275
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
3.9
10.7
31
81
J02AC01
ATC
fluconazole; systemic
1.3
10.6
917
7563
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
5.0
10.5
22
44
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
4.4
10.5
26
60
D06BB10
ATC
imiquimod; topical
2.0
10.4
113
582
A02BC02
ATC
pantoprazole; systemic
1.3
10.3
1464
12948
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
3.0
10.2
43
143
L04AA06
ATC
mycophenolic acid; systemic
3.0
10.0
42
140
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
3.7
9.9
30
81
8720/3-C44.3
ICD-O-3
Malignant melanoma, NOS, of skin of other and unspecified parts of face
16.8
9.9
15
9
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
9.8
341
2399
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
9.8
257
1702
L91.0
ICD-10 Finland
Hypertrophic scar
3.1
9.8
39
126
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
9.5
519
3968
EMB10
NOMESCO Finland
Tonsillectomy
1.8
9.5
136
768
A02BC05
ATC
esomeprazole; systemic
1.3
9.4
849
7009
Z3231
NOMESCO Finland
Registered nurse
1.4
9.4
551
4260
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
12.4
9.4
16
13
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
9.4
715
5764
CBA10
NOMESCO Finland
Biopsy of eyelid
4.0
9.3
26
66
D18.0
ICD-10 Finland
Haemangioma, any site
2.4
9.2
60
251
UJF32
NOMESCO Finland
Coloscopy
1.4
9.2
503
3844
E0000UV, ,
ATC
1.3
9.2
901
7520
Z01.7
ICD-10 Finland
Laboratory examination
1.5
9.2
307
2143
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
9.2
1148
9906
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
9.2
1621
14656
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.6
9.0
244
1628
A98
ICPC
Health maint/preventive medicine
1.9
9.0
2318
22364
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
2.7
8.9
46
172
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
8.8
276
1899
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
8.0
8.8
19
24
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
8.6
351
2546
ZQZ00
NOMESCO Finland
Treatment of several skin areas
6.9
8.5
20
29
Z01.2
ICD-10 Finland
Dental examination
1.3
8.5
1002
8547
J01FA10
ATC
azithromycin; systemic
1.3
8.5
1312
11587
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
8.5
568
4478
D03.30
ICD-10 Finland
Melanoma in situ on the lip
+∞
8.3
8
*
ZXC20
NOMESCO Finland
Use of chemical agents
2.7
8.3
42
156
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.2
854
7157
S08
ICPC
Skin colour change
1.9
8.2
105
572
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
6.8
8.1
19
28
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.0
861
7246
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.0
1630
14863
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
8.0
417
3158
J20
ICD-10 Finland
Acute bronchitis
1.6
8.0
209
1385
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.0
754
6238
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.0
7.9
80
402
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
3.7
7.9
24
65
ZXA10
NOMESCO Finland
Bilateral
1.4
7.9
360
2664
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
13.1
7.9
13
10
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
7.8
7.9
17
22
S59
ICPC
Skin, Other therap proced/minor surg NEC
2.6
7.8
45
178
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.7
7.8
41
155
R60.0
ICD-10 Finland
Localized oedema
1.5
7.8
219
1474
J35.0
ICD-10 Finland
Chronic tonsillitis
1.7
7.8
125
731
M54.5
ICD-10 Finland
Low back pain
1.3
7.7
771
6415
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
3.7
7.7
24
66
-59
ICPC
Other therap proced/minor surg NEC
2.3
7.7
57
254
T78.4
ICD-10 Finland
Allergy, unspecified
1.8
7.7
104
578
J05AB11
ATC
valaciclovir; oral
1.4
7.6
296
2127
J01EA01
ATC
trimethoprim; systemic
1.3
7.6
555
4424
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
7.6
138
836
K07.60
ICD-10 Finland
Snapping jaw
1.7
7.6
125
737
M79.6
ICD-10 Finland
Pain in limb
1.3
7.5
880
7467
-, ,
ICD-10 Finland
2.4
7.5
50
212
G04CA02
ATC
tamsulosin; oral
1.4
7.5
310
2255
WX402
NOMESCO Finland
General anaesthesia
1.4
7.3
429
3305
I73.0
ICD-10 Finland
Raynaud syndrome
2.6
7.2
39
150
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.6
7.2
40
156
WX002
NOMESCO Finland
Sedation and analgesia
1.4
7.2
371
2801
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.2
218
1491
S04
ICPC
Lump/swelling localized
1.5
7.1
213
1455
A12AA04
ATC
calcium carbonate; oral
2.9
7.1
32
112
R4110
NOMESCO Finland
Physiotherapy
1.3
7.1
535
4282
J01AA02
ATC
doxycycline; systemic
1.3
7.0
1684
15526
UJF30
NOMESCO Finland
Ileoscopy through colon
1.5
7.0
199
1344
ZXC15
NOMESCO Finland
Use of photodynamic technique
3.0
6.9
29
97
9734
FHL
Excision and local plastic or associated free skin grafting
4.1
6.8
18
44
J01FA09
ATC
clarithromycin; systemic
1.3
6.8
653
5392
A02BC03
ATC
lansoprazole; oral
1.3
6.7
554
4481
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
3.9
6.7
19
49
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
3.0
6.7
28
94
N63
ICD-10 Finland
Unspecified lump in breast
1.6
6.7
142
897
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
6.6
753
6345
N02BE01
ATC
paracetamol; systemic, rectal
1.3
6.6
2012
19035
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
6.6
528
4255
SCA01
NOMESCO Finland
Preventive oral health care, short
1.3
6.6
629
5188
R01AD08
ATC
fluticasone; nasal
1.3
6.5
603
4949
UJH02
NOMESCO Finland
Anoscopy
1.9
6.5
82
447
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.5
6.5
220
1541
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
6.2
6.5
16
26
R01AD09
ATC
mometasone; nasal
1.2
6.4
991
8643
R74
ICPC
Upper respiratory infection acute
1.3
6.4
710
5957
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
6.4
170
1132
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.3
1505
13758
R06AX27
ATC
desloratadine; oral
1.3
6.3
625
5171
J01DA01
ATC
[U] cefalexin
1.2
6.3
1330
11995
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
6.3
909
7864
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.0
6.3
65
331
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
9.3
6.3
12
13
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
6.2
488
3918
R51.80
ICD-10 Finland
Headache
1.4
6.2
337
2563
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.6
6.2
34
132
H92.0
ICD-10 Finland
Otalgia
1.6
6.2
126
788
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
6.1
477
3824
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.1
532
4328
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.6
6.1
144
933
D06BX02
ATC
ingenol mebutate; topical
3.0
6.1
25
83
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
6.1
850
7324
Z3226
NOMESCO Finland
Physiotherapist
1.4
6.0
347
2662
D07AC01
ATC
betamethasone; topical
1.3
6.0
714
6034
TQW80
NOMESCO Finland
Local dermatologic skincare
2.1
6.0
52
248

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1303
8163
2.29
85.60
2.7
2.0
—
—
—
0
0
464
2491
2.07
39.21
1.4
1.2
—
—
—
0
0
1928
17488
1.51
14.25
19.0
16.4
332.13
332.27
g/l
0.31
1911
17360
1191
9980
1.38
13.40
6.1
5.7
0.04
0.04
e9/l
1.05
1037
8700
1187
9958
1.38
13.18
6.1
5.7
0.55
0.56
e9/l
1.29
1035
8688
1223
10332
1.37
12.88
6.5
5.9
0.19
0.19
e9/l
0.10
1077
9147
637
4862
1.42
12.20
4.2
3.7
92.22
92.64
%
0.17
623
4725
1120
9383
1.36
12.18
6.3
6.2
—
—
—
0
0
2157
20247
1.61
11.67
15.6
14.3
139.72
139.64
mmol/l
0.84
2115
19717
1334
11526
1.35
11.65
9.2
8.7
3.83
4.04
e9/l
3.28
1158
10124
1208
10283
1.35
11.64
6.1
5.7
2.03
1.93
e9/l
0.65
1079
9184
2053
19075
1.51
11.48
4.6
4.2
5.79
5.82
mmol/l
0.74
1920
17519
2161
20308
1.61
11.46
15.8
14.4
3.93
3.95
mmol/l
3.35
2116
19737
474
3464
1.46
11.40
3.2
3.5
236.71
424.57
ng/l
0.71
327
2469
2144
20132
1.58
11.16
14.0
12.9
21.37
22.09
mg/l
0.46
1690
15811
721
5695
1.38
11.11
3.3
3.1
32.01
87.32
e6/l
2.20
550
4331
1666
14953
1.37
11.04
8.0
7.2
76.49
76.51
u/l
0.00
1567
14109
2334
22479
2.13
10.59
21.4
19.0
40.22
40.01
%
0.98
2189
21172
434
3171
1.45
10.36
2.7
2.6
1.95
1.11
e6/l
0.35
237
1762
836
6816
1.35
10.36
3.9
3.5
49.28
99.87
e6/l
2.57
586
4691
1642
14767
1.35
10.31
4.3
3.9
10.49
11.43
mm/h
2.33
1532
13707
2012
18711
1.45
10.30
5.6
4.8
1.84
2.13
mu/l
1.09
1897
17351
2229
21193
1.67
10.23
16.1
14.6
73.95
73.61
umol/l
0.21
2229
21187
2335
22513
2.11
10.22
21.5
19.0
6.63
6.70
e9/l
0.53
2283
21925
2334
22511
2.09
10.02
21.4
18.9
30.15
30.20
pg
0.77
2312
22225
2334
22513
2.08
9.98
21.5
19.0
4.51
4.49
e12/l
1.61
2281
21936
1923
17778
1.40
9.83
5.6
5.2
38.56
39.13
mmol/mol
2.30
1829
16558
2334
22523
2.07
9.81
21.6
19.1
135.03
134.73
g/l
0.53
2310
22237
2333
22510
2.06
9.81
21.4
18.9
90.52
90.70
fl
1.19
2311
22227
964
8075
1.32
9.77
4.7
4.6
36.39
35.93
g/l
2.07
897
7532
1506
13435
1.32
9.62
3.8
3.5
—
—
—
0
0
326
2295
1.49
9.37
1.5
1.7
—
—
—
0
0
2110
19885
1.48
9.28
5.0
4.5
2.79
2.80
mmol/l
0.23
1993
18496
1095
9381
1.31
9.27
6.3
5.8
2.85
2.82
%
0.18
1029
8786
632
5012
1.35
9.19
6.9
6.5
—
—
—
0
0
1063
9078
1.31
9.18
6.3
5.9
0.67
0.67
%
0.06
997
8479
402
2971
1.42
8.92
2.7
2.7
3.80
3.02
e6/l
0.58
208
1573
2328
22497
1.96
8.92
21.5
19.0
256.82
256.68
e9/l
0.04
2282
21969
651
5208
1.34
8.88
3.2
3.0
0.40
0.42
e6/l
0.07
482
3920
2070
19475
1.44
8.81
4.3
4.1
1.49
1.49
mmol/l
0.16
1943
18125
1096
9436
1.30
8.76
6.6
6.1
8.40
8.38
%
0.07
1033
8851
1744
15987
1.33
8.59
4.7
4.1
14.59
14.65
pmol/l
0.50
1618
14697
2078
19591
1.43
8.48
4.4
4.1
4.70
4.73
mmol/l
0.47
1969
18346
1529
13784
1.30
8.41
4.8
4.2
—
—
—
0
0
316
2257
1.46
8.41
1.5
1.4
—
—
—
0
0
899
7583
1.30
8.26
2.0
1.9
100.57
96.19
pmol/l
1.86
447
3936
2000
18751
1.39
8.26
3.9
3.7
1.25
1.27
mmol/l
0.56
1863
17339
308
2202
1.46
8.15
3.0
2.6
7.86
7.34
umol/l
0.16
264
1898
1137
9910
1.28
7.98
6.3
5.9
10.87
10.95
umol/l
0.10
1075
9393
2223
21281
1.56
7.98
11.0
9.8
26.12
25.54
u/l
0.63
2164
20608
2206
21095
1.53
7.83
12.8
12.1
—
—
—
0
0
260
1817
1.48
7.72
2.4
2.3
33.74
64.35
u/l
0.61
216
1552
1116
9738
1.27
7.64
6.3
5.9
29.28
28.56
%
1.45
1054
9160
789
6606
1.29
7.50
3.4
3.1
30.62
32.02
u/l
0.50
749
6295
26
78
3.36
7.38
34.9
27.4
84.77
121.17
ug/l
4.47
26
66
1100
9612
1.27
7.34
6.2
5.7
56.10
56.87
%
1.50
1038
9034
1067
9304
1.26
7.20
6.9
6.3
1.22
1.21
mmol/l
0.29
934
7925
1457
13181
1.27
7.16
4.9
4.3
376.44
1941.43
e6/l
1.73
16
173
438
3405
1.35
7.05
2.9
2.8
2.44
2.45
mmol/l
0.71
364
3004
963
8320
1.26
6.95
2.4
2.3
76.53
76.59
nmol/l
0.02
888
7567
624
5125
1.29
6.76
3.2
2.9
—
—
—
0
0
1882
17631
1.31
6.69
17.8
15.3
14.34
14.69
%
2.42
1855
17316
132
818
1.65
6.67
1.2
1.2
—
—
—
0
0
663
5519
1.28
6.41
5.0
3.8
7.40
7.40
ph
0.33
82
1046
762
6454
1.26
6.38
3.3
3.3
2.36
2.35
mmol/l
0.20
663
5743
1124
9955
1.24
6.32
3.9
3.5
0.00
0.01
estimate
1.32
176
1823
202
1399
1.48
6.28
4.7
3.6
84.31
84.52
ng/l
0.01
186
1220
558
4560
1.29
6.22
4.2
3.5
—
—
—
0
0
616
5122
1.27
5.95
1.7
1.6
1.37
1.37
mmol/l
0.02
555
4348
489
3965
1.29
5.75
2.7
2.5
4.76
6.78
e6/l
2.81
443
3549
197
1383
1.46
5.73
3.7
3.3
4.50
4.51
pmol/l
0.03
174
1229
587
4881
1.27
5.63
2.7
2.5
2436.82
5091.04
umol/l
1.48
520
4329
341
2638
1.34
5.61
2.2
2.3
80.29
117.97
ug/g
3.94
270
2088
285
2148
1.37
5.55
1.3
1.3
—
—
—
0
0
1104
9853
1.22
5.49
5.2
4.8
0.00
0.00
estimate
0.50
179
1868
956
8417
1.22
5.41
6.2
5.6
1.21
1.21
mmol/l
0.01
884
7701
493
4035
1.28
5.35
5.4
4.8
2.28
2.62
ug/l
0.48
437
3601
906
7946
1.22
5.30
3.7
3.3
6.03
5.86
ph
1.02
80
661
706
6046
1.24
5.16
3.1
2.9
—
—
—
0
0
1098
9854
1.21
5.00
3.9
3.5
0.00
0.00
estimate
0.99
187
1967
1233
11200
1.21
4.91
4.4
4.5
6.47
6.59
mmol/l
1.18
1142
10403
19
62
3.08
4.79
2.0
2.9
—
—
—
0
0
1048
9394
1.20
4.75
3.3
2.8
101.29
103.59
ug/l
0.08
990
8739
644
5516
1.23
4.62
2.0
2.1
139.18
206.18
u/l
2.57
611
5205
263
2016
1.34
4.60
1.5
1.4
—
—
—
0
0
302
2363
1.32
4.59
3.0
2.9
0.73
0.74
ug/l
0.10
193
1513
661
5689
1.22
4.51
3.2
3.1
7.75
7.46
mmol/l
0.76
581
4854
298
2336
1.31
4.47
5.8
5.4
1.06
1.04
mmol/l
0.63
279
2166
96
615
1.58
4.35
1.2
1.2
—
—
—
0
0
1047
9473
1.19
4.08
2.7
2.5
—
—
—
0
0
133
931
1.45
4.01
2.8
2.7
0.10
0.28
e6/l
2.22
127
900
1460
13605
1.18
3.97
3.1
3.0
47.37
43.51
u/l
0.57
1379
12784
335
2720
1.27
3.84
1.2
1.2
—
—
—
0
0
621
5390
1.20
3.80
3.7
3.7
12.49
8.95
mg/mmol
0.54
387
3375
165
1216
1.38
3.74
2.4
3.2
83.50
46.31
u/ml
0.54
159
1175
591
5115
1.21
3.72
3.3
3.2
186.66
340.58
mg/l
0.57
391
3219
151
1102
1.39
3.64
2.4
2.1
11.40
12.05
nmol/l
0.39
145
989
113
783
1.46
3.62
1.4
1.3
242.30
229.30
miu/ml
0.13
51
375
559
4827
1.21
3.59
1.3
1.3
0.75
1.45
u/ml
3.93
130
1295
344
2825
1.25
3.58
1.4
1.3
732.97
512.73
titre
0.68
74
583
503
4306
1.21
3.53
4.5
3.9
1.02
1.02
kg/l
0.09
67
630
123
876
1.43
3.42
1.1
1.1
—
—
—
0
0
128
920
1.41
3.39
7.1
10.8
—
—
—
0
0
913
8262
1.17
3.36
12.3
13.3
1.15
1.21
inr
1.76
247
2466
208
1616
1.31
3.36
1.3
1.2
122.06
150.05
iu/ml
0.57
83
626
520
4488
1.20
3.34
2.0
1.7
1.09
1.06
mg/l
0.08
399
3389
208
1621
1.31
3.29
6.0
8.5
123.64
121.64
g/l
0.76
202
1579
90
609
1.50
3.27
1.5
1.4
8.57
11.41
u/l
1.68
74
491
6
7
8.59
3.26
1.2
1.0
—
—
—
0
0
337
2793
1.24
3.23
2.6
2.1
29.98
29.49
s
0.65
326
2700
132
967
1.39
3.15
2.6
2.4
—
—
—
0
0
352
2946
1.23
3.08
3.3
3.3
0.82
0.82
mmol/l
0.32
329
2775
88
604
1.47
3.01
2.3
2.6
—
—
—
0
0
480
4154
1.19
2.98
1.5
1.4
2.06
2.30
g/l
2.26
283
2586
26
127
2.06
2.97
6.4
6.6
—
—
—
0
0
243
1963
1.26
2.93
5.5
7.7
0.92
1.08
mmol/l
0.25
181
1540
409
3493
1.21
2.93
1.3
1.3
4.94
10.45
u/ml
2.01
148
1410
157
1202
1.33
2.85
1.3
1.3
24.51
28.29
iu/l
0.77
142
1017
13
47
2.78
2.81
1.2
1.4
—
—
—
0
0
963
8839
1.15
2.80
9.0
8.9
0.00
0.00
e9/l
0.00
768
7236
37
209
1.78
2.79
5.2
4.5
342.03
92.86
u/ml
0.56
12
57
80
548
1.48
2.78
2.5
3.0
—
—
—
0
0
10
28
3.58
2.78
1.3
1.3
117.44
83.82
ng/l
—
10
28
47
285
1.66
2.76
1.6
1.5
—
—
—
0
0
34
188
1.82
2.75
1.1
1.1
—
—
—
0
0
112
819
1.39
2.74
1.3
1.3
1.18
1.08
u/ml
0.03
13
63
669
6000
1.16
2.66
2.5
2.5
59.97
71.94
u/l
0.40
619
5559
81
562
1.46
2.66
1.9
1.9
2.86
4.83
iu/l
2.26
23
210
421
3642
1.19
2.61
1.3
1.3
31.65
29.99
iu/ml
0.06
121
1172
122
913
1.35
2.60
2.2
1.8
—
—
—
0
0
171
1345
1.29
2.58
1.5
1.4
—
—
—
0
0
240
1968
1.24
2.57
5.6
7.7
5.12
5.09
kpa
0.22
228
1881
81
570
1.44
2.49
4.4
7.2
1.13
1.29
mmol/l
0.96
71
497
239
1969
1.24
2.46
5.6
7.7
12.67
12.65
kpa
0.01
227
1883
41
250
1.65
2.40
1.6
1.6
—
—
—
0
0
38
227
1.68
2.40
1.3
1.5
—
—
—
0
0
141
1093
1.31
2.39
2.1
2.2
4247.93
5472.76
u/l
0.20
54
446
54
354
1.54
2.36
1.3
1.4
3.00
4.14
ug/l
0.73
45
326
185
1495
1.26
2.27
7.2
7.2
9.94
9.15
mmol/l
0.74
171
1431
503
4466
1.16
2.26
2.0
1.9
—
—
—
0
0
23
120
1.93
2.25
1.2
1.2
—
—
—
0
0
58
392
1.49
2.22
4.9
8.9
10.69
11.32
mmol/l
0.82
51
355
211
1737
1.24
2.21
5.9
8.2
95.97
95.72
%
0.24
199
1680
58
393
1.49
2.19
4.9
8.8
105.22
105.29
mmol/l
0.05
51
356
53
353
1.51
2.18
1.2
1.2
—
—
—
0
0
430
3785
1.17
2.17
2.8
2.7
532.93
535.17
mosm/kgh2o
0.08
377
3252
171
1379
1.26
2.15
1.3
1.3
161.75
194.25
u/ml
0.44
164
1269
83
605
1.39
2.13
2.0
1.7
0.22
0.24
g/l
0.66
78
572
19
95
2.01
2.10
2.3
2.2
18.38
102.83
ug/l
0.50
19
83
232
1943
1.21
2.07
2.9
2.7
1.72
1.81
%
0.61
208
1728
7
20
3.51
2.05
1.0
1.1
—
—
—
0
0
177
1442
1.25
2.05
7.9
8.2
—
—
—
0
0
477
4254
1.15
2.02
1.6
1.5
20.78
20.86
nmol/l
0.04
423
3658
687
6278
1.13
2.01
2.5
2.3
—
—
—
0
0
312
2694
1.18
2.00
2.8
2.3
2.41
2.37
g/l
0.68
295
2492
215
1796
1.22
1.98
3.4
4.1
27.94
21.14
ug/l
0.12
162
1431
162
1315
1.25
1.95
1.3
1.2
—
—
—
0
0
25
420
0.59
1.89
3.6
3.6
43.46
24.70
mg/l
0.68
16
269
55
383
1.45
1.86
1.1
1.1
1.81
2.03
u/ml
0.06
32
197
191
2278
0.82
1.81
4.3
4.2
33.53
32.51
%
0.65
132
1610
45
304
1.49
1.78
1.4
1.4
—
—
—
0
0
16
297
0.54
1.74
6.6
5.4
408.69
368.40
umol/l
0.66
16
257
64
465
1.39
1.73
1.2
1.1
0.88
2.80
u/ml
2.53
38
236
41
274
1.50
1.71
1.2
1.2
—
—
—
0
0
56
399
1.41
1.70
1.2
1.1
0.89
1.45
u/ml
0.38
31
169
23
133
1.74
1.70
1.0
1.1
2.03
11.09
iu/ml
—
8
36
27
164
1.65
1.68
2.5
3.1
17.82
37.51
mg/l
0.69
21
117
291
2540
1.17
1.66
1.8
1.6
—
—
—
0
0
113
899
1.27
1.65
7.0
9.7
24.11
24.30
mmol/l
0.33
108
873
17
90
1.90
1.65
3.5
3.0
—
—
—
0
0
31
197
1.58
1.62
3.4
3.0
2.39
32.04
nmol/l
0.54
31
192
332
2934
1.15
1.61
2.8
2.3
73.35
13.59
umol/l
0.50
317
2732
57
413
1.39
1.59
1.2
1.1
6.64
5.25
u/ml
0.26
39
216
168
1406
1.21
1.56
2.4
2.4
37.40
23.13
au/ml
0.71
15
120
13
64
2.04
1.54
1.3
1.2
—
—
—
0
0
144
1189
1.22
1.54
1.3
1.2
—
—
—
0
0
32
480
0.66
1.53
3.6
3.6
7.41
7.42
ph
0.54
32
425
39
265
1.48
1.53
1.3
1.3
—
0.41
nmol/l
—
0
17
65
486
1.35
1.51
1.1
1.1
—
—
—
0
0
125
1523
0.81
1.50
3.0
3.3
1.23
1.23
mmol/l
0.14
108
1313
25
154
1.63
1.50
1.2
1.1
—
—
—
0
0
9
37
2.44
1.48
1.0
1.1
—
—
—
0
0
40
276
1.46
1.47
1.1
1.1
0.70
0.39
u/ml
0.24
15
83
64
480
1.34
1.46
1.3
1.2
—
5.71
—
0
9
71
541
1.32
1.46
3.2
2.3
—
—
—
0
0
9
38
2.37
1.45
1.2
1.6
—
—
—
0
0
165
1391
1.20
1.44
2.7
2.7
101.26
181.70
ng/l
6.79
149
1256
11
52
2.12
1.44
1.5
1.9
146.00
167.69
e6/l
—
5
26
21
125
1.69
1.43
2.7
2.5
0.18
0.21
e9/l
0.64
16
110
275
2420
1.15
1.43
1.7
1.8
—
—
—
0
0
200
1718
1.18
1.42
1.1
1.2
—
—
—
0
0
44
313
1.41
1.39
1.8
1.5
0.92
0.74
g/l
0.30
37
234
78
610
1.29
1.35
3.0
3.6
321.60
6438.87
u/ml
0.76
63
527
281
2489
1.15
1.34
3.1
2.4
22.56
23.29
%
0.41
237
2134
24
151
1.60
1.34
2.2
2.2
—
—
—
0
0
157
1328
1.19
1.34
3.0
2.8
—
—
—
0
0
215
1870
1.16
1.32
2.3
2.1
378.87
378.12
nmol/l
0.02
199
1715
23
144
1.60
1.32
1.2
1.3
—
—
—
0
0
23
144
1.60
1.32
1.4
1.5
81.09
77.60
umol/l
0.32
23
144
60
784
0.76
1.32
4.0
3.7
—
—
—
0
0
98
793
1.25
1.30
1.8
1.6
—
—
—
0
0
21
129
1.63
1.30
2.7
2.4
480.31
563.85
e6/l
0.31
16
110
28
185
1.52
1.29
1.5
2.5
1.07
1.26
g/24h
0.18
13
91
170
1456
1.18
1.27
2.0
2.3
5.11
6.76
ug/l
0.96
142
1280
516
4762
1.11
1.25
2.5
2.2
—
—
—
0
0
35
245
1.43
1.23
1.3
1.3
—
—
—
0
0
47
347
1.36
1.23
1.7
1.8
—
—
—
0
0
8
37
2.17
1.21
1.0
1.1
—
—
—
0
0
41
297
1.39
1.20
1.1
1.1
5.28
5.78
u/ml
0.05
20
121
22
140
1.58
1.20
2.6
1.9
12.27
11.11
%
0.73
22
140
165
1418
1.18
1.20
2.7
2.7
68.93
71.20
e9/l
0.33
123
1073
131
1105
1.20
1.18
3.7
5.4
—
—
—
0
0
21
133
1.58
1.17
1.0
1.0
—
—
—
0
0
53
404
1.32
1.14
1.6
1.4
—
—
—
0
0
44
326
1.36
1.14
1.5
1.5
—
—
—
0
0
297
2675
1.13
1.13
2.1
2.0
—
—
—
0
0
29
200
1.46
1.12
1.4
1.4
—
—
—
0
0
11
58
1.90
1.12
1.2
1.4
—
—
—
0
0
26
176
1.48
1.10
2.5
2.3
1.10
1.26
e9/l
0.46
20
160
365
3987
0.90
1.08
1.6
1.6
429.83
30258074.12
pmol/l
3.52
313
3338
13
74
1.76
1.06
1.5
2.0
6.46
10.84
%
1.11
13
69
34
245
1.39
1.05
1.7
1.5
21.82
45.69
mu/l
1.88
29
221
47
612
0.76
1.05
1.4
1.5
—
—
—
0
0
7
33
2.12
1.05
1.1
1.7
—
—
—
0
0
7
33
2.12
1.05
1.9
1.2
5.31
5.73
nmol/l
—
7
33
33
237
1.40
1.04
1.3
1.3
—
—
nmol/l
—
0
0
156
1354
1.16
1.03
1.4
1.4
—
—
—
0
0
193
1702
1.15
1.03
1.3
1.4
—
—
—
0
0
7
34
2.06
1.03
1.3
1.0
—
—
—
0
0
7
34
2.06
1.03
1.3
1.0
—
—
—
0
0
7
34
2.06
1.03
1.3
1.0
—
—
—
0
0
85
699
1.22
1.02
4.0
6.1
1.66
1.60
%
0.23
78
654
126
1076
1.18
1.02
5.3
7.3
24.66
24.48
mmol/l
0.20
119
1022
85
701
1.22
1.00
4.1
6.1
0.89
0.91
%
0.18
78
658
0
29
0.00
0.97
0.0
2.1
—
3.04
—
0
11
21
140
1.50
0.97
2.5
2.3
695.81
622.47
ml
0.49
16
94
0
30
0.00
0.97
0.0
1.1
—
1.69
—
0
18
9
50
1.80
0.96
5.2
4.8
—
—
—
0
0
97
816
1.20
0.94
1.1
1.1
—
—
—
0
0
90
752
1.20
0.94
3.4
2.2
21.52
20.95
s
0.49
73
650
107
909
1.19
0.94
1.8
1.6
319.57
306.04
mu/l
0.18
99
818
6
118
0.51
0.94
2.2
2.7
32001.48
39684.31
ug/l
—
6
118
92
771
1.20
0.93
2.8
1.8
1.23
1.53
g/l
2.79
78
676
23
158
1.46
0.93
1.7
1.5
0.82
0.96
g/l
2.04
23
158
16
101
1.59
0.93
2.2
1.4
228.15
157.29
pmol/l
0.68
16
101
134
1162
1.16
0.92
2.0
1.8
1.83
1.36
g/l
0.49
122
1065
52
410
1.27
0.92
1.5
1.5
0.34
0.41
nmol/l
0.39
44
323
48
608
0.79
0.90
1.4
1.4
—
—
—
0
0
46
358
1.29
0.90
1.5
1.4
19.02
25.94
u/l
0.99
39
299
42
323
1.31
0.90
1.2
1.2
—
—
—
0
0
44
341
1.30
0.89
2.6
2.4
—
—
—
0
0
46
359
1.29
0.88
1.6
1.7
—
—
—
0
0
124
1073
1.16
0.88
7.1
9.2
94.11
93.95
%
0.12
124
1067
42
324
1.30
0.88
1.0
1.1
1.82
4.38
u/ml
1.30
23
154
50
627
0.79
0.87
1.4
1.5
—
—
—
0
0
23
161
1.43
0.86
1.1
1.1
—
—
—
0
0
43
334
1.29
0.86
1.2
1.2
4.68
4.58
u/ml
0.03
19
145
19
128
1.49
0.86
1.1
1.1
—
—
—
0
0
511
4801
1.08
0.85
4.2
4.2
—
—
—
0
0
48
380
1.27
0.84
5.7
2.6
—
—
—
0
0
124
1079
1.16
0.83
7.0
9.1
0.66
0.68
%
0.29
124
1072
0
24
0.00
0.79
0.0
1.1
—
1371.75
—
0
16
0
25
0.00
0.79
0.0
1.0
—
1.54
—
0
16
47
375
1.26
0.78
1.6
1.4
98.93
110.09
u/ml
—
9
65
12
74
1.62
0.78
2.7
2.0
1.44
1.13
ug/l
0.28
12
68
9
53
1.70
0.75
1.1
1.1
—
—
—
0
0
40
315
1.27
0.75
1.1
1.0
2.03
2.21
u/ml
0.09
22
156
175
1573
1.12
0.75
4.8
3.5
1.50
1.91
mmol/l
1.02
147
1313
9
54
1.67
0.74
1.0
1.0
—
—
—
0
0
190
1717
1.12
0.74
2.1
2.2
0.22
0.22
g/l
0.64
175
1615
27
356
0.76
0.72
2.7
2.4
16.24
16.37
%
0.08
19
175
521
4932
1.07
0.72
2.4
2.1
2.75
2.90
mg/l
0.56
460
4205
396
3712
1.08
0.71
1.8
1.7
—
—
—
0
0
12
76
1.58
0.71
1.3
1.6
12.47
14.03
pmol/l
0.64
12
63
26
196
1.33
0.67
1.3
1.4
3.12
2.93
g/l
0.20
21
132
72
613
1.18
0.67
1.1
1.1
3.25
4.17
u/ml
0.13
14
85
21
153
1.38
0.67
1.1
1.2
—
—
—
0
0
5
28
1.79
0.66
1.0
1.5
7.10
415794.40
nmol/l
—
5
19
13
86
1.51
0.66
1.3
1.1
155.61
188.91
iu/ml
0.36
13
86
11
70
1.57
0.65
1.5
2.4
—
—
—
0
0
52
624
0.83
0.65
15.1
9.0
—
—
—
0
0
166
1503
1.11
0.65
3.9
3.4
—
—
—
0
0
94
1073
0.87
0.64
3.5
3.5
7.42
7.41
ph
0.29
14
131
167
1839
0.90
0.64
4.5
3.9
—
—
—
0
0
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
12
79
1.52
0.62
3.1
2.9
—
—
—
0
0
26
199
1.31
0.62
1.2
1.4
7.72
8.39
mmol/l
0.35
26
193
0
22
0.00
0.59
0.0
1.4
—
5.93
—
0
12
121
1083
1.12
0.59
7.1
9.0
1.35
1.36
%
0.04
121
1076
10
64
1.56
0.58
3.0
3.3
—
—
—
0
0
96
1084
0.88
0.58
3.5
3.5
5.07
5.17
kpa
0.80
89
1036
17
123
1.38
0.57
1.4
1.2
—
—
—
0
0
16
115
1.39
0.56
1.9
1.4
18.04
24.56
umol/l
0.45
16
109
17
124
1.37
0.55
1.1
1.4
5.03
6.21
u/l
0.80
12
103
13
90
1.45
0.55
1.1
1.6
—
—
—
0
0
21
159
1.32
0.55
1.3
1.1
70.00
166.36
titre
—
6
33
9
61
1.48
0.53
1.6
1.2
—
—
—
0
0
32
393
0.81
0.53
3.5
3.9
4.95
5.04
kpa
0.31
32
387
13
91
1.43
0.53
1.7
3.3
7.45
7.42
ph
—
6
28
32
392
0.81
0.52
3.5
3.9
2.84
2.55
mmol/l
0.20
19
265
32
392
0.81
0.52
3.5
3.9
8.89
8.66
kpa
0.34
32
386
15
109
1.38
0.51
1.5
1.2
—
—
—
0
0
13
92
1.42
0.50
1.1
1.1
1457.15
1640.33
miu/ml
0.25
13
92
6
41
1.46
0.50
1.3
1.2
—
—
—
0
0
16
118
1.36
0.50
2.8
2.8
43.75
43.04
%
—
8
65
277
2605
1.07
0.50
1.6
1.7
—
—
—
0
0
172
1587
1.09
0.50
4.9
3.5
5.84
5.84
kpa
0.00
164
1541
7
45
1.56
0.49
1.0
1.1
0.09
7.40
u/ml
—
7
38
19
145
1.31
0.48
1.1
1.4
43.50
30.59
nmol/l
0.90
14
125
13
93
1.40
0.48
1.5
1.2
—
—
—
0
0
36
299
1.21
0.48
1.3
1.5
—
—
—
0
0
12
166
0.72
0.47
1.1
1.1
—
—
—
0
0
17
222
0.76
0.47
2.9
2.6
—
—
—
0
0
179
1662
1.08
0.46
1.7
1.4
—
—
—
0
0
8
119
0.67
0.45
1.3
1.2
—
11.08
—
0
13
30
247
1.22
0.44
1.0
1.2
—
—
—
0
0
497
4782
1.05
0.43
2.7
2.9
1109.81
1227.17
ng/l
0.28
401
4012
34
285
1.20
0.42
1.8
1.6
—
—
—
0
0
343
3269
1.06
0.42
1.6
1.7
1105.88
1186.86
nmol/l
0.95
251
2492
53
462
1.15
0.42
1.6
1.5
143.67
1521.92
e6/l
1.48
42
378
53
462
1.15
0.42
1.5
1.4
24.44
39.08
e6/l
0.38
41
361
6
91
0.66
0.42
1.7
2.6
1760.67
1960.09
ml
—
6
81
5
33
1.52
0.41
1.6
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
190.71
—
0
7
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
37
434
0.85
0.41
1.2
1.2
—
—
—
0
0
40
342
1.17
0.41
1.3
1.1
—
—
—
0
0
17
132
1.29
0.40
1.1
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
161
1726
0.93
0.39
3.6
3.7
—
—
—
0
0
8
61
1.31
0.39
1.3
1.4
—
—
—
0
0
35
297
1.18
0.39
2.3
1.9
—
4.17
—
0
6
5
35
1.43
0.39
1.6
1.3
30.20
23.04
%
—
5
27
39
453
0.86
0.39
4.1
4.3
—
—
—
0
0
10
71
1.41
0.39
5.2
3.5
85.60
63.12
mg/l
—
10
52
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
46
400
1.15
0.39
1.3
1.3
—
—
—
0
0
13
170
0.76
0.38
1.2
1.2
39.63
40.99
mg/l
0.05
13
143
9
67
1.34
0.38
1.7
1.9
—
—
—
0
0
543
5253
1.04
0.38
4.6
3.8
0.00
0.00
estimate
1.28
175
1828
44
383
1.15
0.37
2.2
2.2
127.74
130.01
g/l
0.28
34
287
14
107
1.31
0.37
1.9
1.4
9.86
13.14
u/l
1.66
14
101
122
1317
0.92
0.36
1.8
1.7
—
—
—
0
0
5
76
0.66
0.35
2.2
2.3
126.00
151.13
nmol/l
—
5
67
9
124
0.72
0.35
20.3
13.6
975.44
876.97
nmol/l
—
9
119
52
461
1.13
0.35
1.3
1.2
27.00
44.61
u/ml
—
6
41
124
1152
1.08
0.34
3.1
2.5
—
—
—
0
0
27
227
1.19
0.34
1.5
1.2
—
—
—
0
0
16
200
0.80
0.34
2.6
2.5
—
—
—
0
0
29
246
1.18
0.34
2.9
2.5
—
—
—
0
0
45
396
1.14
0.34
3.1
3.7
55.87
57.21
%
0.35
45
396
55
615
0.89
0.34
3.3
3.7
1.23
1.37
mmol/l
0.65
55
606
42
368
1.14
0.33
3.1
4.0
—
—
—
0
0
6
47
1.28
0.32
1.8
2.1
—
—
—
0
0
21
174
1.21
0.31
1.7
2.1
—
—
—
0
0
7
96
0.73
0.31
1.7
2.5
—
—
—
0
0
34
296
1.15
0.30
2.0
2.6
—
—
—
0
0
60
543
1.11
0.30
1.3
1.2
77.00
88.10
titre
—
10
42
13
163
0.80
0.29
1.2
1.1
271.62
255.32
mg/l
0.09
13
142
19
157
1.21
0.29
1.1
1.1
—
—
—
0
0
158
1493
1.06
0.29
2.7
2.7
10.06
10.63
g/l
0.93
146
1361
10
76
1.32
0.28
1.1
1.2
—
0.30
—
0
6
20
168
1.19
0.27
1.4
1.5
36.33
35.13
%
0.04
12
104
8
67
1.19
0.26
1.4
1.3
—
—
—
0
0
111
1042
1.07
0.26
6.3
7.1
24.49
24.81
mmol/l
0.50
111
1035
28
320
0.87
0.25
3.3
3.2
0.83
0.82
nmol/l
0.03
19
254
38
425
0.89
0.25
1.4
1.4
—
—
—
0
0
138
1307
1.06
0.25
3.7
2.9
4.68
4.61
kpa
0.15
131
1266
35
311
1.13
0.25
1.5
1.4
6.87
7.18
mmol/l
0.29
30
276
37
413
0.89
0.24
2.9
2.6
—
—
—
0
0
38
341
1.12
0.23
1.2
1.1
—
—
—
0
0
33
370
0.89
0.23
3.7
3.4
—
—
—
0
0
14
115
1.22
0.23
1.1
1.1
—
—
—
0
0
15
179
0.84
0.23
2.9
2.7
—
—
—
0
0
21
242
0.87
0.22
1.4
1.2
—
—
—
0
0
48
524
0.91
0.22
1.2
1.3
—
—
—
0
0
559
5474
1.03
0.22
3.1
3.2
—
—
—
0
0
54
497
1.09
0.21
3.9
3.7
147.92
66.99
mg/l
0.43
40
411
727
7396
0.98
0.21
2.5
2.6
—
—
—
0
0
245
2367
1.04
0.21
1.4
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
48
523
0.92
0.21
3.4
3.8
3.90
3.86
mmol/l
0.32
48
517
0
12
0.00
0.21
0.0
1.1
—
0.13
—
0
7
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
11
89
1.24
0.21
2.4
1.3
130.82
166.80
mmol/24h
1.12
11
89
54
499
1.08
0.20
3.9
3.7
29.19
73.52
mg/l
0.98
40
414
0
14
0.00
0.20
0.0
1.4
—
12.06
—
0
14
0
14
0.00
0.20
0.0
1.1
—
0.05
—
0
6
46
422
1.09
0.20
2.7
2.3
46.60
91.34
ug/min
1.35
32
262
16
136
1.18
0.20
1.5
1.3
1.62
1.59
g/l
0.16
16
136
26
231
1.13
0.19
1.2
1.1
—
—
—
0
0
49
452
1.09
0.19
1.3
1.8
24499.64
11707.64
e6/l
0.41
33
333
16
186
0.86
0.19
1.0
1.0
—
—
—
0
0
34
372
0.91
0.17
2.5
3.1
30.48
35.05
umol/l
0.94
29
339
16
184
0.87
0.17
1.1
1.4
23578.00
109710.12
e6/l
—
9
125
19
167
1.14
0.17
3.6
3.1
52.50
54.22
%
0.10
12
148
54
577
0.93
0.16
1.4
1.3
—
—
—
0
0
91
866
1.05
0.16
1.9
2.0
—
—
—
0
0
24
215
1.12
0.16
1.2
1.6
—
—
—
0
0
536
5270
1.02
0.16
3.5
3.6
—
—
—
0
0
20
225
0.89
0.16
1.5
2.0
—
—
—
0
0
145
1399
1.04
0.15
3.2
2.7
67.38
66.65
g/l
0.58
136
1279
9
82
1.10
0.15
2.0
1.7
—
—
—
0
0
19
212
0.90
0.14
1.4
1.3
—
—
—
0
0
8
96
0.83
0.13
2.8
2.0
—
—
—
0
0
12
103
1.17
0.13
1.7
1.4
—
—
—
0
0
14
122
1.15
0.13
1.1
1.0
—
—
—
0
0
60
568
1.06
0.13
1.2
1.2
—
—
—
0
0
84
804
1.05
0.13
4.0
2.5
1.34
1.25
%
0.33
84
799
697
6888
1.02
0.13
3.3
3.4
23.48
45.18
ng/l
2.60
405
4342
14
159
0.88
0.13
1.1
1.5
11.56
11.29
umol/l
0.04
14
149
11
94
1.17
0.13
1.1
1.8
—
—
—
0
0
57
540
1.06
0.13
1.4
1.4
316.16
296.38
ug/g
0.27
32
289
18
161
1.12
0.13
1.0
1.2
—
—
—
0
0
30
324
0.92
0.12
1.0
1.1
82.80
1734.67
iu/ml
—
5
77
35
375
0.93
0.12
1.2
1.1
—
—
—
0
0
69
659
1.05
0.12
2.6
2.7
—
—
—
0
0
21
191
1.10
0.11
1.0
1.1
—
—
—
0
0
35
374
0.93
0.11
1.2
1.1
—
—
—
0
0
14
124
1.13
0.11
1.0
1.0
0.11
2.91
u/ml
—
5
29
70
672
1.04
0.10
3.5
4.5
—
—
—
0
0
21
193
1.09
0.10
1.9
3.0
—
—
—
0
0
12
135
0.89
0.09
1.8
1.5
—
—
—
0
0
16
145
1.10
0.09
1.4
2.0
3.39
3.86
mg/l
0.29
16
138
17
185
0.92
0.08
1.4
1.2
—
—
—
0
0
5
64
0.78
0.08
1.0
1.1
—
—
—
0
0
31
328
0.94
0.08
1.7
2.2
6.41
4.63
umol/l
0.39
25
239
7
64
1.09
0.08
1.0
1.3
—
—
—
0
0
11
123
0.89
0.08
1.1
1.2
—
—
—
0
0
144
1410
1.02
0.08
2.9
2.8
3.95
5.19
e9/l
1.62
121
1183
7
80
0.87
0.07
1.0
1.2
—
—
—
0
0
7
83
0.84
0.07
1.0
1.0
—
—
—
0
0
9
85
1.06
0.07
1.0
1.1
—
—
—
0
0
33
314
1.05
0.07
1.6
1.3
62.12
64.77
mmol/l
0.14
26
256
217
2200
0.99
0.06
1.3
1.3
—
—
—
0
0
9
105
0.86
0.06
2.2
1.6
—
—
—
0
0
14
152
0.92
0.06
1.1
1.5
1.67
1.19
promille
—
9
124
590
5941
0.99
0.06
1.5
1.5
—
—
—
0
0
12
109
1.10
0.06
1.2
1.4
149.77
135.58
nmol/l
0.76
12
109
36
345
1.04
0.06
1.4
1.6
—
—
—
0
0
73
711
1.03
0.06
1.4
1.2
—
—
—
0
0
99
969
1.02
0.06
3.5
3.3
—
—
—
0
0
22
233
0.94
0.05
1.3
1.7
58.64
59.10
%
0.01
11
154
19
202
0.94
0.05
1.3
2.3
—
—
—
0
0
164
1618
1.01
0.05
3.6
4.0
0.87
0.98
%
0.18
51
521
13
121
1.07
0.03
2.1
3.3
—
—
—
0
0
92
935
0.98
0.03
1.9
2.0
—
—
—
0
0
146
1477
0.99
0.03
3.5
3.8
0.57
0.66
%
0.26
46
451
14
131
1.07
0.03
1.6
1.4
2078.86
1903.67
ml
0.38
14
126
66
647
1.02
0.03
1.9
2.0
0.97
1.69
ug/l
0.61
56
565
26
270
0.96
0.03
3.7
3.4
1.75
1.32
%
0.28
20
244
40
390
1.03
0.02
1.7
2.1
0.72
0.86
nmol/l
1.08
34
324
15
158
0.95
0.02
1.4
1.5
—
—
—
0
0
56
550
1.02
0.02
1.3
1.2
2.20
2.30
u/ml
—
5
60
95
940
1.01
0.02
1.9
2.0
—
—
—
0
0
13
137
0.95
0.01
1.5
1.4
—
—
—
0
0
17
163
1.04
0.01
1.1
1.1
391.06
397.60
nmol/l
0.05
17
147
154
1547
1.00
0.00
3.7
4.0
0.02
0.11
%
2.37
41
448
19
196
0.97
0.00
6.8
3.7
—
—
—
0
0
95
944
1.01
0.00
1.9
2.0
—
—
—
0
0
145
1456
1.00
0.00
3.9
4.1
0.08
0.55
%
0.82
37
363
10
99
1.01
0.00
1.6
1.2
14.60
10.40
u/l
—
10
88
11
111
0.99
0.00
1.0
1.0
678.40
696.40
ng/l
—
5
72
15
149
1.01
0.00
1.5
1.4
—
—
—
0
0
42
415
1.01
0.00
1.4
1.2
214.38
257.52
u/ml
0.67
26
262
20
204
0.98
0.00
1.2
1.5
—
—
—
0
0
11
112
0.98
0.00
1.0
1.0
343.00
314.01
ng/l
—
5
74
92
924
1.00
0.00
1.9
1.9
—
—
—
0
0
63
632
1.00
0.00
3.1
3.3
0.22
0.28
g/l
0.46
32
249
74
738
1.00
0.00
2.0
2.0
—
—
—
0
0
26
263
0.99
0.00
2.0
3.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
64.83
—
0
6
8
83
0.96
-0.00
1.6
2.7
—
—
—
0
0
5
56
0.89
-0.00
1.2
1.3
47.28
48.71
%
—
5
50
0
5
0.00
-0.00
0.0
1.2
—
116.00
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
1234.00
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
64
0.94
-0.00
1.7
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.0
—
402.80
—
0
5
5
51
0.98
-0.00
2.0
1.1
338.20
295.08
pmol/l
—
5
37
0
9
0.00
-0.00
0.0
3.9
—
—
—
0
0
5
52
0.96
-0.00
4.0
7.3
27.86
25.50
mmol/l
—
5
47
9
97
0.93
-0.00
1.7
2.0
1.23
2.27
ug/l
—
9
81
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
3.07
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_FACE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_FACE 0.859 [0.77, 0.96] 0.009
Birth year 0.997 [0.99, 1.01] 0.513

During the follow-up period (1.1.1998 — 31.12.2019), 755 out of 8978 females with CD2_BENIGN_MELANOCYTIC_FACE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_FACE 0.856 [0.76, 0.97] 0.013
Birth year 0.993 [0.98, 1.0] 0.108

During the follow-up period (1.1.1998 — 31.12.2019), 590 out of 4616 males with CD2_BENIGN_MELANOCYTIC_FACE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_FACE.

N-year risk Females Males
1 0.072% 0.191%
5 0.436% 1.109%
10 1.176% 2.921%
15 2.395% 5.773%
20 4.597% 9.912%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_FACE – Melanocytic naevi of other and unspecified parts of face

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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