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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of breast, lobular

CD2_INSITU_BREAST_LOBULAR

breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D05.0&
  • Cause of death: ICD-10 D05.0&

2 out of 7 registries used, show all original rules.

260

4. Check minimum number of events

None

260

5. Include endpoints

None

260

6. Filter based on genotype QC (FinnGen only)

253

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D05
Name in latin
Carcinoma in situ lobulare mammae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 253 253 -
Unadjusted period prevalence (%) 0.09 0.09 -
Median age at first event (years) 58.86 58.86 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
260
Matched controls
2600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D05.0
ICD-10 Finland
Lobular carcinoma in situ
+∞
307.7
259
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
69.9
236.1
142
44
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
49.1
114.2
69
19
PJA12
NOMESCO Finland
Sentinel node biopsy
10.8
84.9
139
249
HAC20
NOMESCO Finland
Total mastectomy
12.5
74.4
88
102
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
27.8
67.7
48
21
HAB99
NOMESCO Finland
Other partial excision of mammary gland
15.7
65.8
63
52
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
20.9
63.4
51
30
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
8.0
55.8
101
192
HA1AA
NOMESCO Finland
X-ray mammography
7.5
55.3
111
235
TQW20
NOMESCO Finland
Tatoe
24.7
54.3
40
19
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
9.8
51.9
70
94
115
Kela drug reimbursment
Breast cancer
6.9
51.8
118
281
HAB40
NOMESCO Finland
Wedge excision of mammary gland
7.7
50.1
90
168
C50.99
ICD-10 Finland
Breast, unspecified
9.1
41.2
57
78
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
6.5
40.8
84
177
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
221.4
37.9
38
*
N63
ICD-10 Finland
Unspecified lump in breast
6.8
37.5
71
137
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
12.9
37.1
38
34
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
9.8
34.9
44
53
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
13.8
34.8
34
28
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
8.6
32.0
45
62
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
8.8
31.6
43
57
L02BA01
ATC
tamoxifen; oral
6.5
31.0
59
113
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
339.8
30.5
30
*
L02BG04
ATC
letrozole; oral
4.8
27.2
77
209
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
9.3
27.2
35
43
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
7.7
26.8
41
62
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
11.5
26.7
29
28
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
5.5
26.7
61
138
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
32.3
26.1
34
12
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
5.3
25.2
59
136
C50
ICD-10 Finland
Malignant neoplasm of breast
7.2
24.3
39
62
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
5.5
22.6
49
105
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
7.7
22.2
33
48
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
8.5
18.6
25
32
HAE99
NOMESCO Finland
Other reconstruction of breast
23.9
18.6
26
12
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.5
17.7
37
76
D24
ICD-10 Finland
Benign neoplasm of breast
7.0
15.7
25
39
WZC00
NOMESCO Finland
Treatment plan or consultation
2.9
15.5
135
713
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
6.2
14.9
27
48
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
5.1
14.7
33
72
ZZR10
NOMESCO Finland
Flap of skin and muscle
17.0
14.2
22
14
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
4.0
13.8
43
122
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
5.5
13.7
28
56
A04AA02
ATC
granisetron; systemic, transdermal
4.1
13.6
42
118
XX3DW
NOMESCO Finland
Time consuming IT work
3.3
12.8
56
199
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
6.6
12.7
21
34
ZZF00
NOMESCO Finland
Graft of adipose tissue
17.0
12.3
19
12
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
12.2
98
484
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.1
12.0
35
94
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
5.9
11.9
22
40
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
11.7
87
413
H02AB02
ATC
dexamethasone; systemic
2.9
11.4
64
262
C50.92
ICD-10 Finland
Malignant tumor in another specified localization in lobular gland, lobular tumor
18.1
11.4
17
10
Z31.5
ICD-10 Finland
Genetic counselling
4.1
11.0
32
86
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
10.6
131
778
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
16.9
10.5
16
10
X76
ICPC
Malignant neoplasm breast female
4.9
10.5
24
53
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
24.5
10.4
14
6
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.8
9.8
23
52
TQB05
NOMESCO Finland
Puncture of skin of trunk
12.0
9.7
17
15
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
9.2
9.5
19
22
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
11.3
9.4
17
16
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
5.1
9.2
20
42
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
16.3
9.1
14
9
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.6
9.1
22
51
HA4MT
NOMESCO Finland
Labeling mammary gland pathology with X-ray guidance
25.0
9.0
12
5
L02BG03
ATC
anastrozole; oral
5.2
9.0
19
39
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
4.4
8.6
22
53
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
8.0
138
909
X21
ICPC
Breast sympt/compl female other
6.3
7.9
20
34
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
4.8
7.8
18
40
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
46.4
7.8
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
3.1
7.5
33
116
HAD20
NOMESCO Finland
Liposuction of breast
82.3
7.5
8
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
3.9
7.4
22
60
HAA10
NOMESCO Finland
Biopsy of mammary gland
16.3
7.3
11
7
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
4.7
7.3
17
38
WX402
NOMESCO Finland
General anaesthesia
2.2
7.2
71
373
ZXA05
NOMESCO Finland
Left side
2.1
7.1
89
514
H03BB01
ATC
carbimazole; oral
3.9
6.9
21
58
8500/2-C50.4
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-outer quadrant of breast
41.2
6.8
8
*
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
12.7
6.6
11
9
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
3.9
6.6
20
55
L02BG06
ATC
exemestane; oral
4.1
6.6
18
46
C50.00
ICD-10 Finland
Malignant tumor of nipple and areola, no histological veryfication
14.8
6.4
10
7
8520/3-C50.4
ICD-O-3
Lobular carcinoma, NOS, of upper-outer quadrant of breast
9.6
6.4
12
13
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
6.2
122
818
L03AA13
ATC
pegfilgrastim; parenteral
2.9
6.2
30
112
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
5.4
6.1
17
33
HAD99
NOMESCO Finland
Other plastic operation on breast
8.9
6.1
12
14
N64.9
ICD-10 Finland
Disorder of breast, unspecified
10.4
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
85
5.54
19.47
2.6
3.6
42.66
27.51
u/ml
0.34
41
85
45
112
4.65
17.22
1.5
1.3
—
—
—
0
0
62
248
2.97
11.50
1.7
1.4
—
—
—
0
0
66
310
2.51
8.78
1.4
1.2
—
—
—
0
0
107
688
1.94
6.17
2.3
2.1
—
—
—
0
0
171
1295
1.94
5.90
7.9
5.7
9.08
9.75
umol/l
0.92
163
1214
13
25
5.41
4.84
1.2
1.1
—
—
—
0
0
51
282
2.01
4.39
4.4
3.9
4.91
11.50
ug/l
1.57
40
239
138
1034
1.71
4.37
2.9
2.1
—
—
—
0
0
215
1834
2.00
4.33
9.5
7.2
81.82
79.16
u/l
0.24
208
1701
120
879
1.68
4.04
3.9
3.4
2.40
2.37
mmol/l
2.58
109
768
138
1051
1.67
3.98
2.6
2.3
—
—
—
0
0
167
1355
1.65
3.61
9.7
8.7
3.54
3.85
e9/l
1.36
146
1181
149
1209
1.54
2.96
7.7
5.5
1.23
1.23
mmol/l
0.37
129
1016
16
68
2.44
2.61
2.2
1.5
4.32
5.74
iu/l
—
6
21
253
2411
2.83
2.53
19.3
15.8
70.47
69.50
umol/l
0.30
253
2411
80
599
1.48
2.18
7.1
6.5
—
—
—
0
0
199
1777
1.51
2.10
3.9
4.3
12.72
12.87
mm/h
0.06
181
1620
9
32
2.88
2.02
1.9
1.8
—
—
—
0
0
190
1687
1.47
2.01
3.6
3.8
—
—
—
0
0
48
345
1.48
1.58
3.1
2.9
2.75
3.87
e6/l
0.56
23
164
6
21
2.90
1.51
8.3
2.7
9.43
3.43
nmol/l
—
6
21
129
1104
1.33
1.51
6.1
4.7
1.23
1.22
mmol/l
0.33
123
999
203
1869
1.39
1.40
19.9
17.5
329.54
330.18
g/l
0.53
203
1861
56
426
1.40
1.37
3.4
3.8
80.93
155.80
ng/l
0.60
41
325
5
17
2.98
1.36
6.2
2.2
—
—
—
0
0
119
1018
1.31
1.35
4.0
3.7
36.54
35.81
g/l
0.84
108
950
0
38
0.00
1.35
0.0
1.8
—
53.67
—
0
38
120
1034
1.30
1.28
9.8
10.8
1.13
1.16
inr
0.22
37
313
118
1020
1.29
1.21
10.0
8.9
0.00
0.00
e9/l
0.86
97
828
40
294
1.43
1.19
1.8
1.9
—
—
—
0
0
238
2273
1.56
1.18
14.8
13.0
23.60
20.46
mg/l
0.60
192
1751
28
193
1.51
1.15
1.8
1.6
—
—
—
0
0
122
1074
1.26
1.04
2.5
2.3
85.43
80.15
nmol/l
1.11
112
947
43
551
0.74
1.04
1.4
1.2
0.48
2.45
u/ml
—
8
153
65
530
1.30
1.02
3.3
3.8
—
—
—
0
0
92
786
1.26
1.00
4.4
3.7
104.09
91.55
e6/l
0.08
57
544
44
559
0.74
1.00
2.7
2.5
333.00
6705.03
umol/l
2.75
39
477
0
30
0.00
0.98
0.0
3.4
—
—
—
0
0
68
562
1.28
0.96
4.0
3.3
102.21
96.23
%
1.36
68
545
11
63
1.78
0.91
1.5
2.7
—
—
—
0
0
14
216
0.63
0.90
2.3
2.0
325.21
363.97
nmol/l
0.31
14
206
8
45
1.80
0.85
3.0
2.0
—
—
—
0
0
72
610
1.25
0.83
3.0
2.9
—
—
—
0
0
9
147
0.60
0.82
1.2
1.3
—
—
—
0
0
58
481
1.26
0.80
2.7
2.5
2.48
2.46
mmol/l
0.53
52
427
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
65
548
1.25
0.78
1.6
1.6
2.00
0.98
mg/l
0.51
58
437
77
662
1.23
0.78
3.4
3.1
19.67
31.65
e6/l
0.57
53
499
0
27
0.00
0.78
0.0
1.0
—
—
—
0
0
72
833
0.81
0.77
3.8
3.0
—
—
—
0
0
34
429
0.76
0.74
1.9
1.7
1057.31
1255.35
nmol/l
0.78
27
300
21
151
1.43
0.74
1.1
1.4
—
—
—
0
0
11
68
1.64
0.73
1.7
1.9
849.85
219.86
ug/l
0.41
11
61
72
621
1.22
0.71
3.2
3.0
0.31
0.52
e6/l
0.62
48
454
29
223
1.34
0.70
5.6
3.3
1.23
1.24
mmol/l
0.08
29
193
56
471
1.24
0.69
2.2
2.5
6.27
5.90
e6/l
0.08
44
428
41
335
1.27
0.65
3.0
3.0
0.86
0.81
mmol/l
1.12
41
311
54
631
0.82
0.63
2.9
4.5
0.00
0.00
estimate
-0.00
16
218
117
1066
1.18
0.63
4.7
5.9
—
—
—
0
0
87
971
0.84
0.62
2.1
1.9
99.46
99.26
pmol/l
0.01
38
430
87
775
1.18
0.60
5.5
3.5
7.39
7.40
ph
0.75
18
153
140
1300
1.17
0.58
3.7
4.0
6.46
6.51
mmol/l
0.14
133
1211
5
86
0.57
0.57
3.8
4.7
—
—
—
0
0
13
181
0.70
0.55
1.2
1.4
—
—
—
0
0
46
534
0.83
0.50
2.3
2.2
2.71
3.30
mg/l
1.01
38
454
7
45
1.57
0.49
3.6
2.4
1.31
1.46
mmol/l
—
7
45
49
423
1.20
0.49
3.4
2.8
466.73
495.76
mosm/kgh2o
0.46
33
366
5
83
0.59
0.46
1.0
1.1
—
—
—
0
0
15
197
0.75
0.46
2.4
3.4
—
—
—
0
0
7
50
1.41
0.45
6.3
4.2
—
—
—
0
0
79
715
1.15
0.45
4.0
3.5
—
—
—
0
0
82
745
1.15
0.44
2.8
2.1
54.87
54.70
u/l
0.02
72
675
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
184
1912
0.87
0.43
5.3
4.5
15.12
14.88
pmol/l
0.61
170
1729
5
32
1.57
0.42
1.6
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
61
545
1.16
0.41
1.2
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
157.67
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
23313.33
—
0
12
78
710
1.14
0.41
1.6
1.6
1.28
1.37
mmol/l
0.49
58
591
124
1163
1.13
0.40
5.0
5.3
1.84
1.95
e9/l
0.30
108
1029
0
18
0.00
0.40
0.0
1.6
—
9.77
—
0
18
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
15
116
1.31
0.38
3.6
6.7
0.85
0.68
%
1.45
15
116
15
116
1.31
0.38
1.3
1.5
—
—
—
0
0
235
2302
1.22
0.37
4.6
4.7
4.95
4.90
mmol/l
0.31
220
2117
41
466
0.86
0.36
1.2
1.3
8.89
12.65
u/ml
0.26
17
182
85
784
1.13
0.36
3.3
3.0
—
—
—
0
0
15
117
1.30
0.36
3.6
6.6
1.18
1.38
%
0.57
15
117
239
2346
1.23
0.36
14.9
12.2
—
—
—
0
0
60
542
1.14
0.35
2.9
3.9
—
—
—
0
0
6
43
1.40
0.35
4.0
2.5
5.92
7.04
mmol/l
—
6
43
121
1141
1.11
0.35
5.1
5.3
0.04
0.04
e9/l
1.33
102
982
33
285
1.18
0.34
1.6
2.1
88.22
132.65
ug/g
0.75
23
227
44
492
0.87
0.32
1.8
1.7
162857580.91
473.25
pmol/l
0.49
35
378
16
196
0.80
0.31
3.3
4.1
—
—
—
0
0
24
281
0.84
0.30
2.1
2.1
23.29
21.43
%
0.28
19
235
52
573
0.88
0.30
1.6
1.5
23.93
23.06
nmol/l
0.17
44
476
120
1138
1.10
0.30
5.1
5.3
0.55
0.54
e9/l
0.08
101
981
122
1158
1.10
0.30
3.0
4.0
0.00
0.00
estimate
-0.00
15
213
26
223
1.18
0.29
2.5
2.2
27.85
28.47
u/l
0.07
20
187
8
109
0.73
0.29
1.4
1.3
—
—
—
0
0
26
224
1.18
0.28
3.4
6.0
5.12
5.24
kpa
0.35
26
219
74
687
1.11
0.28
2.9
2.9
6.30
6.55
mmol/l
0.21
62
566
8
64
1.26
0.27
7.4
2.8
—
—
—
0
0
26
225
1.17
0.27
3.4
6.0
2.06
1.49
mmol/l
0.40
21
193
224
2198
1.14
0.26
4.0
4.1
1.24
1.26
mmol/l
0.19
204
1992
9
77
1.17
0.24
1.2
1.4
—
—
—
0
0
28
247
1.15
0.24
3.7
5.0
105.14
103.73
mmol/l
0.83
28
247
34
378
0.88
0.23
1.4
1.1
—
—
—
0
0
7
94
0.74
0.22
1.3
1.2
—
—
—
0
0
120
1150
1.08
0.22
4.4
5.2
0.00
0.00
estimate
-0.00
15
213
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
21
182
1.17
0.22
1.6
1.1
209.75
130.76
iu/ml
—
10
76
149
1442
1.08
0.21
4.0
2.8
61.48
45.57
u/l
0.68
132
1329
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.12
—
0
5
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
56.10
—
0
10
0
12
0.00
0.21
0.0
1.3
—
132.72
—
0
12
0
12
0.00
0.21
0.0
1.2
—
465.08
—
0
12
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
65.23
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
48
1.26
0.20
12.8
5.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
1.96
—
0
14
0
14
0.00
0.20
0.0
1.0
—
244.33
—
0
9
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
118
1135
1.07
0.20
3.0
4.0
0.00
0.00
estimate
-0.00
17
228
232
2290
1.12
0.18
4.6
4.6
1.65
1.62
mmol/l
0.50
213
2096
35
320
1.11
0.18
2.3
1.7
28.20
29.47
s
0.94
35
307
82
860
0.93
0.18
3.3
3.5
25.77
60.51
ng/l
0.40
55
603
7
63
1.11
0.17
1.0
1.0
—
—
—
0
0
5
66
0.75
0.17
4.2
2.2
10.52
10.86
mg/l
—
5
60
5
69
0.72
0.17
4.4
5.5
1.02
1.14
mmol/l
—
5
62
122
1180
1.06
0.17
5.1
5.5
0.17
0.18
e9/l
0.24
105
1033
48
512
0.92
0.16
2.5
4.5
1.02
1.02
kg/l
—
9
63
16
182
0.87
0.15
4.2
4.0
0.83
0.61
%
—
6
51
12
140
0.85
0.15
1.2
1.3
—
—
—
0
0
232
2294
1.11
0.15
4.9
4.7
5.84
5.84
mmol/l
0.01
213
2080
17
192
0.88
0.15
4.0
4.2
0.17
0.17
%
—
6
55
18
202
0.88
0.15
3.9
4.1
1.00
0.98
%
—
7
65
11
93
1.19
0.14
2.0
1.6
—
—
—
0
0
13
112
1.17
0.14
3.4
2.8
0.15
0.12
e6/l
0.10
13
107
14
160
0.87
0.14
2.4
2.7
—
—
—
0
0
70
668
1.07
0.14
3.0
3.0
13.88
137.67
mg/l
0.59
48
376
26
237
1.11
0.14
4.4
2.2
6.79
6.22
umol/l
0.12
21
205
12
139
0.86
0.14
3.6
2.3
—
—
—
0
0
8
96
0.83
0.14
3.7
2.7
24.79
25.44
mmol/l
—
8
96
22
199
1.12
0.14
1.5
1.3
—
—
—
0
0
8
100
0.79
0.14
3.0
2.7
16.25
1450.35
u/ml
—
8
87
26
238
1.10
0.13
6.8
3.6
—
—
—
0
0
9
109
0.82
0.13
1.6
1.9
—
—
—
0
0
94
970
0.95
0.12
2.4
2.7
132.79
95.04
ug/l
0.66
85
881
44
464
0.94
0.11
2.1
1.5
2.12
2.39
g/l
0.59
20
264
161
1582
1.05
0.11
4.5
4.6
—
—
—
0
0
237
2351
1.09
0.10
5.2
5.3
2.82
2.86
mmol/l
0.26
220
2149
24
222
1.09
0.10
1.8
1.5
—
—
—
0
0
32
301
1.07
0.10
1.7
1.2
—
—
—
0
0
46
481
0.95
0.09
1.2
1.3
28.61
35.26
iu/ml
0.21
16
168
6
54
1.11
0.09
4.7
2.4
1.97
1.46
mg/l
—
6
46
7
67
1.05
0.08
5.9
9.5
—
—
—
0
0
222
2203
1.05
0.07
6.1
5.4
1.81
2.46
mu/l
0.62
207
1998
7
85
0.82
0.07
1.1
1.2
—
2.16
—
0
12
30
285
1.06
0.07
1.8
1.3
—
—
—
0
0
16
173
0.92
0.07
1.4
1.1
—
—
—
0
0
35
335
1.05
0.06
1.2
1.3
504.00
680.00
titre
—
10
87
9
105
0.85
0.06
4.6
6.1
—
—
—
0
0
16
172
0.93
0.06
1.2
1.3
—
—
—
0
0
17
181
0.93
0.05
4.0
4.3
0.17
0.02
%
—
6
42
19
180
1.06
0.04
5.1
2.5
66.42
67.23
g/l
0.24
19
167
11
119
0.92
0.04
1.5
1.3
—
—
—
0
0
22
230
0.95
0.03
1.6
1.6
—
—
—
0
0
219
2179
1.03
0.03
5.9
5.7
39.47
39.36
mmol/mol
0.08
203
2006
10
108
0.92
0.03
2.6
1.7
—
—
—
0
0
71
699
1.02
0.03
3.7
3.5
5.06
6.10
mg/mmol
0.13
49
383
17
162
1.05
0.02
5.8
2.3
—
—
—
0
0
20
208
0.96
0.02
1.5
1.4
—
—
—
0
0
19
184
1.04
0.00
1.6
1.3
—
—
—
0
0
13
132
0.98
0.00
3.0
4.7
—
—
—
0
0
15
152
0.99
0.00
1.1
1.2
67.52
160.18
u/ml
2.26
15
142
17
169
1.01
0.00
2.1
2.6
—
22.77
—
0
10
15
154
0.97
0.00
3.1
5.8
—
—
—
0
0
12
115
1.05
0.00
4.2
3.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
5.92
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1527.60
—
0
5
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
-0.00
1.8
1.6
5.44
4.89
mmol/24h
—
6
52
0
9
0.00
-0.00
0.0
1.3
—
86.38
—
0
9
0
6
0.00
-0.00
0.0
18.5
—
1121.33
—
0
6
8
80
1.00
-0.00
2.1
1.5
0.26
4.50
ug/l
—
8
75
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
50
1.00
-0.00
1.6
3.1
4.66
4.60
e9/l
—
5
50
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
60
1.00
-0.00
3.3
4.9
3.83
3.78
mmol/l
—
6
60
61
610
1.00
-0.00
2.9
3.6
—
—
—
0
0
8
84
0.95
-0.00
1.0
1.1
—
—
—
0
0
6
67
0.89
-0.00
2.3
2.6
—
—
—
0
0
5
52
0.96
-0.00
2.6
3.6
62.40
59.62
%
—
5
52
0
6
0.00
-0.00
0.0
20.7
—
2496.33
—
0
6
7
78
0.89
-0.00
1.1
2.3
1.89
1.58
g/l
—
7
67

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_BREAST_LOBULAR – Carcinoma in situ of breast, lobular

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).