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Carcinoma in situ of breast, lobular

CD2_INSITU_BREAST_LOBULAR

breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D05.0&
  • Cause of death: ICD-10 D05.0&

2 out of 7 registries used, show all original rules.

244

4. Check minimum number of events

None

244

5. Include endpoints

None

244

6. Filter based on genotype QC (FinnGen only)

244

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D05
Name in latin
Carcinoma in situ lobulare mammae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 244 244 -
Unadjusted period prevalence (%) 0.08 0.08 -
Median age at first event (years) 58.32 58.32 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
214
Matched controls
2140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D05.0
ICD-10 Finland
Lobular carcinoma in situ
+∞
306.6
213
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
62.3
102.4
119
42
PJA12
NOMESCO Finland
Sentinel node biopsy
13.4
55.3
112
162
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
33.3
43.5
57
23
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
12.0
41.7
84
109
HA1AA
NOMESCO Finland
X-ray mammography
10.2
40.8
92
147
HAC20
NOMESCO Finland
Total mastectomy
14.4
39.6
71
71
115
Kela drug reimbursment
Breast cancer
8.5
35.9
91
171
HAB40
NOMESCO Finland
Wedge excision of mammary gland
10.7
35.9
76
105
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
377.5
32.8
32
*
HAB99
NOMESCO Finland
Other partial excision of mammary gland
15.3
31.7
54
46
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
34.8
31.2
40
14
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
25.6
28.7
40
19
TQW20
NOMESCO Finland
Tatoe
40.1
27.5
34
10
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
7.6
25.1
64
113
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
64.0
24.7
28
5
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
41.6
23.7
29
8
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
9.4
22.2
48
64
N63
ICD-10 Finland
Unspecified lump in breast
7.4
21.8
56
98
C50.99
ICD-10 Finland
Breast, unspecified
9.7
21.4
45
57
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
16.9
20.2
32
22
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
14.2
19.9
34
28
L02BA01
ATC
tamoxifen; oral
7.3
17.9
45
75
HAE99
NOMESCO Finland
Other reconstruction of breast
46.3
17.6
21
5
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
9.0
17.6
38
50
L02BG04
ATC
letrozole; oral
6.0
17.3
51
106
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
10.6
16.9
33
36
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
7.4
16.7
41
66
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
5.9
16.5
49
102
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
6.2
16.1
46
91
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
12.2
16.1
29
27
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
11.4
16.1
30
30
ZZR10
NOMESCO Finland
Flap of skin and muscle
27.4
15.0
20
8
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
7.7
14.5
34
51
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
10.0
13.2
26
29
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
7.0
12.9
32
52
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
28.6
12.2
16
6
ZZF00
NOMESCO Finland
Graft of adipose tissue
22.9
12.2
17
8
C50
ICD-10 Finland
Malignant neoplasm of breast
8.0
12.0
27
38
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
10.2
11.8
23
25
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
5.8
11.5
33
65
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
11.1
100
514
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
10.5
11.0
21
22
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
7.2
10.9
26
40
XX3DW
NOMESCO Finland
Time consuming IT work
3.9
10.9
48
148
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
10.0
10.8
21
23
D24
ICD-10 Finland
Benign neoplasm of breast
10.0
10.8
21
23
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
10.5
86
411
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
34.4
10.5
13
*
A04AA02
ATC
granisetron; systemic, transdermal
4.8
10.3
35
84
H02AB02
ATC
dexamethasone; systemic
3.6
10.1
49
164
C50.92
ICD-10 Finland
Malignant tumor in another specified localization in lobular gland, lobular tumor
27.5
9.9
13
5
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
13.2
9.5
16
13
TQB05
NOMESCO Finland
Puncture of skin of trunk
16.5
9.2
14
9
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
17.2
8.7
13
8
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
8.6
74
355
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
6.0
8.6
23
42
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
6.5
8.4
21
35
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
8.7
8.3
17
21
X76
ICPC
Malignant neoplasm breast female
6.3
8.2
21
36
HA4MT
NOMESCO Finland
Labeling mammary gland pathology with X-ray guidance
26.1
7.6
10
*
Z31.5
ICD-10 Finland
Genetic counselling
4.5
7.5
26
64
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
14.0
7.5
12
9
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
5.9
7.4
20
37
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
4.1
7.4
28
75
ZXA05
NOMESCO Finland
Left side
2.4
7.2
71
365
L02BG03
ATC
anastrozole; oral
6.8
6.8
16
25
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
8.2
6.7
14
18
HAD99
NOMESCO Finland
Other plastic operation on breast
12.8
6.7
11
9
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
6.6
110
714
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
8.6
6.4
13
16
NK6AN
NOMESCO Finland
Total body bone isotope imaging
8.6
6.4
13
16
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
18.7
6.3
9
5

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
38
79
5.51
17.99
2.7
3.4
45.1
26.6
u/ml
0.40
38
79
42
106
4.58
15.80
1.5
1.3
—
—
—
0
0
58
234
2.94
10.61
1.7
1.4
—
—
—
0
0
62
291
2.52
8.29
1.4
1.2
—
—
—
0
0
101
651
1.94
5.81
2.3
2.1
—
—
—
0
0
12
24
5.21
5.80
1.3
1.1
—
—
—
0
0
161
1217
1.95
5.65
8.0
5.7
8.9
9.8
umol/l
1.62
153
1136
131
965
1.77
4.60
2.9
2.1
—
—
—
0
0
49
268
2.04
4.37
4.4
3.9
5.0
11.9
ug/l
1.55
38
226
201
1729
1.92
3.74
9.6
7.2
82.4
79.3
u/l
0.27
194
1600
156
1263
1.65
3.44
9.6
8.7
3.6
3.9
e9/l
1.26
136
1100
110
820
1.62
3.37
4.1
3.4
2.4
2.4
mmol/l
2.08
99
711
16
61
2.74
3.20
2.3
1.5
4.3
6.2
iu/l
—
6
18
140
1138
1.54
2.76
7.6
5.6
1.2
1.2
mmol/l
0.67
120
949
237
2256
2.76
2.25
19.5
16.0
70.2
69.7
umol/l
0.17
237
2256
188
1669
1.55
2.18
3.9
4.3
13.0
12.9
mm/h
0.03
170
1517
34
511
0.61
1.92
1.4
1.2
0.5
2.6
u/ml
—
6
141
73
559
1.44
1.76
7.2
6.7
—
—
—
0
0
6
19
3.21
1.67
8.3
2.8
9.4
3.4
nmol/l
—
6
19
176
1585
1.40
1.53
3.6
3.8
—
—
—
0
0
102
851
1.34
1.43
5.9
7.8
1.1
1.1
inr
0.47
28
256
5
17
2.98
1.36
6.2
2.2
—
—
—
0
0
64
500
1.38
1.36
3.3
3.8
—
—
—
0
0
6
24
2.54
1.31
1.0
1.2
—
—
—
0
0
189
1740
1.38
1.30
19.7
17.8
329.5
330.1
g/l
0.41
189
1732
224
2129
1.64
1.30
14.9
13.1
24.4
20.7
mg/l
0.69
181
1635
53
407
1.39
1.24
3.6
3.8
89.2
159.1
ng/l
0.51
37
313
120
1041
1.30
1.23
5.7
4.8
1.2
1.2
mmol/l
0.57
113
937
111
954
1.30
1.22
4.3
3.7
36.5
35.8
g/l
0.78
100
889
111
955
1.30
1.21
9.5
9.0
0.0
0.0
e9/l
0.86
90
778
201
1878
1.40
1.19
17.0
14.3
37.7
39.2
%
1.20
144
1274
40
528
0.71
1.17
2.7
2.5
332.0
7180.0
umol/l
2.75
35
444
0
36
0.00
1.15
0.0
1.8
—
54.0
—
0
36
7
32
2.22
1.09
2.1
1.8
—
—
—
0
0
12
200
0.58
1.04
2.4
1.9
316.0
368.9
nmol/l
0.38
12
190
81
683
1.28
1.00
4.3
5.3
—
—
—
0
0
33
243
1.41
0.99
16.7
17.2
1.3
1.2
inr
—
8
38
0
29
0.00
0.98
0.0
3.4
—
—
—
0
0
25
177
1.46
0.93
1.8
1.5
—
—
—
0
0
36
277
1.35
0.85
1.8
2.0
—
—
—
0
0
63
525
1.27
0.85
4.1
3.3
102.5
95.9
%
1.47
63
510
113
1007
1.23
0.84
5.0
5.7
28.9
28.8
%
0.03
108
925
19
132
1.48
0.78
1.2
1.4
—
—
—
0
0
0
27
0.00
0.78
0.0
8.3
—
6.7
—
0
20
31
398
0.75
0.77
2.0
1.7
1066.4
1251.1
nmol/l
0.64
24
280
54
449
1.26
0.74
2.8
2.5
2.5
2.5
mmol/l
0.77
48
398
6
106
0.56
0.74
1.8
3.2
4.7
5.2
kpa
—
6
98
10
60
1.70
0.73
1.5
2.7
—
—
—
0
0
28
213
1.36
0.72
3.5
3.4
1.2
1.2
mmol/l
0.03
28
183
10
61
1.67
0.69
1.8
1.9
932.6
220.1
ug/l
—
10
54
7
42
1.69
0.69
3.1
2.0
—
—
—
0
0
50
593
0.80
0.68
2.8
4.4
0.0
0.0
estimate
0.00
15
205
5
28
1.80
0.66
1.0
1.1
—
—
—
0
0
5
28
1.80
0.66
1.6
1.3
—
—
—
0
0
61
522
1.22
0.65
1.5
1.7
2.0
1.0
mg/l
0.45
54
420
68
777
0.83
0.64
3.6
3.0
—
—
—
0
0
6
105
0.56
0.63
1.5
3.2
—
7.4
—
0
18
77
680
1.19
0.60
4.0
3.5
—
—
—
0
0
82
916
0.84
0.60
2.0
1.9
100.4
99.3
pmol/l
0.07
36
399
80
716
1.17
0.53
3.4
3.1
—
—
—
0
0
12
167
0.70
0.51
1.2
1.4
—
—
—
0
0
51
442
1.19
0.49
2.3
2.5
5.1
6.0
e6/l
0.39
39
393
116
1075
1.15
0.48
4.8
5.3
1.9
1.9
e9/l
0.11
99
947
7
49
1.44
0.46
6.3
4.2
—
—
—
0
0
27
220
1.26
0.46
7.0
3.6
—
—
—
0
0
77
695
1.16
0.46
2.7
2.1
54.7
54.8
u/l
0.01
68
626
131
1228
1.14
0.46
3.5
4.0
6.5
6.5
mmol/l
0.06
124
1141
221
2156
1.27
0.45
4.7
4.7
4.9
4.9
mmol/l
0.30
205
1976
114
1060
1.14
0.44
4.9
5.3
0.0
0.0
e9/l
1.03
94
908
14
104
1.37
0.44
1.2
1.5
—
—
—
0
0
21
261
0.79
0.44
2.2
2.2
22.7
21.2
%
0.18
16
216
14
184
0.75
0.43
2.4
3.4
—
—
—
0
0
82
748
1.14
0.42
4.7
3.7
111.8
87.6
e6/l
0.16
53
517
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
279.9
—
0
10
0
16
0.00
0.41
0.0
1.6
—
10.1
—
0
16
12
160
0.74
0.41
1.4
1.2
—
—
—
0
0
113
1055
1.13
0.41
4.8
5.3
0.6
0.5
e9/l
0.37
94
904
225
2204
1.27
0.40
14.7
12.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
69
628
1.14
0.36
3.6
3.1
20.4
32.6
e6/l
0.53
49
472
65
590
1.14
0.36
3.3
3.0
0.3
0.5
e6/l
0.43
44
429
9
125
0.71
0.36
1.2
1.3
—
—
—
0
0
38
433
0.86
0.35
1.2
1.5
2.1
2.4
g/l
0.52
17
244
44
495
0.86
0.35
2.3
2.1
2.5
3.3
mg/l
2.16
36
418
6
44
1.37
0.34
4.0
2.5
1.4
1.4
mmol/l
—
6
44
15
188
0.78
0.34
3.2
4.1
—
—
—
0
0
10
133
0.74
0.34
3.0
2.4
—
—
—
0
0
44
390
1.16
0.34
3.2
2.7
485.8
509.4
mosm/kgh2o
0.35
29
336
71
652
1.13
0.33
2.8
2.9
6.2
6.6
mmol/l
0.48
59
529
173
1788
0.89
0.33
5.4
4.5
15.1
14.9
pmol/l
0.42
159
1610
20
167
1.22
0.29
1.6
1.1
183.1
139.8
iu/ml
—
9
69
63
579
1.12
0.29
3.2
2.9
—
—
—
0
0
10
76
1.33
0.28
5.3
2.2
39.3
38.1
g/l
—
10
71
8
62
1.30
0.28
7.5
2.9
—
—
—
0
0
79
737
1.11
0.28
5.0
3.5
7.4
7.4
ph
0.49
17
145
72
670
1.11
0.26
1.6
1.6
1.3
1.4
mmol/l
0.11
52
554
56
514
1.12
0.26
1.1
1.3
—
—
—
0
0
5
72
0.69
0.26
1.2
2.1
2.0
1.6
g/l
—
5
62
210
2059
1.14
0.26
4.1
4.1
1.3
1.3
mmol/l
0.05
191
1861
14
170
0.81
0.26
2.9
4.7
1.5
1.2
mmol/l
0.20
14
163
218
2143
1.16
0.26
4.6
4.6
1.6
1.6
mmol/l
0.33
199
1953
115
1097
1.09
0.25
4.9
5.5
0.2
0.2
e9/l
0.08
98
958
53
487
1.11
0.25
2.8
4.5
—
—
—
0
0
39
431
0.89
0.25
1.3
1.3
8.9
13.1
u/ml
0.29
17
165
6
85
0.70
0.24
1.3
1.2
—
—
—
0
0
7
93
0.75
0.23
4.1
2.6
25.6
25.5
mmol/l
—
7
93
8
104
0.76
0.21
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
143.0
—
0
11
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.17
0.21
4.6
2.5
6.2
7.0
mmol/l
—
5
43
32
354
0.89
0.21
1.4
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
1.3
—
0
7
0
14
0.00
0.20
0.0
1.0
—
2.0
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
113
1087
1.07
0.19
3.0
3.9
0.0
0.0
estimate
0.00
14
199
223
2203
1.14
0.18
5.2
5.3
2.8
2.9
mmol/l
0.24
206
2004
50
535
0.92
0.18
1.6
1.5
23.7
23.2
nmol/l
0.09
42
442
7
60
1.17
0.18
1.0
1.0
—
—
—
0
0
7
61
1.15
0.17
5.9
9.4
—
—
—
0
0
5
67
0.74
0.17
4.4
5.6
1.0
1.2
mmol/l
—
5
60
67
635
1.08
0.17
2.9
3.0
14.5
143.9
mg/l
0.59
45
358
110
1062
1.07
0.16
3.0
3.9
0.0
0.0
estimate
0.00
14
203
25
226
1.12
0.16
4.6
2.2
6.9
6.3
umol/l
0.12
20
195
78
815
0.94
0.15
3.2
3.5
26.7
62.7
ng/l
0.40
51
575
43
459
0.92
0.15
1.8
1.7
162857580.9
480.8
pmol/l
0.49
35
348
7
88
0.79
0.15
1.7
3.2
24.6
25.0
mmol/l
—
7
79
8
97
0.82
0.14
3.0
2.7
16.3
1484.4
u/ml
—
8
85
16
180
0.88
0.13
3.0
3.0
—
—
—
0
0
111
1077
1.06
0.13
4.6
5.1
0.0
0.0
estimate
0.00
14
200
218
2157
1.10
0.13
4.8
4.8
5.9
5.9
mmol/l
0.05
198
1953
209
2065
1.08
0.13
6.0
5.3
1.8
2.5
mu/l
0.59
194
1864
11
94
1.18
0.13
3.5
6.2
24.3
24.9
mmol/l
0.36
11
89
13
114
1.15
0.12
3.2
6.7
0.9
0.7
%
1.28
13
114
13
114
1.15
0.12
3.2
6.7
1.2
1.4
%
0.32
13
114
15
134
1.13
0.11
1.1
1.2
60.5
161.9
u/ml
2.23
15
124
5
47
1.07
0.09
8.6
5.5
—
—
—
0
0
59
569
1.05
0.08
2.8
3.6
—
—
—
0
0
18
195
0.92
0.08
1.6
1.4
—
—
—
0
0
15
164
0.91
0.08
1.2
1.3
—
—
—
0
0
53
511
1.05
0.08
3.0
3.8
—
—
—
0
0
20
186
1.08
0.07
3.3
6.1
115.0
118.8
g/l
0.42
20
181
22
206
1.07
0.07
1.7
1.6
—
—
—
0
0
30
285
1.06
0.07
1.7
1.2
—
—
—
0
0
10
89
1.13
0.07
1.9
1.6
—
—
—
0
0
12
132
0.90
0.07
1.2
1.3
—
—
—
0
0
9
102
0.88
0.06
4.6
6.2
—
—
—
0
0
9
105
0.85
0.06
1.6
1.9
—
—
—
0
0
23
218
1.06
0.05
1.7
1.6
—
—
—
0
0
23
218
1.06
0.05
3.3
6.0
5.2
5.2
kpa
0.14
23
213
43
443
0.96
0.04
1.2
1.3
30.2
35.1
iu/ml
0.14
15
152
206
2048
1.04
0.04
5.9
5.7
39.7
39.4
mmol/mol
0.22
190
1881
150
1486
1.02
0.04
4.4
4.6
—
—
—
0
0
68
667
1.03
0.04
3.8
3.8
5.3
6.3
mg/mmol
0.11
46
366
17
161
1.06
0.03
2.1
2.7
—
5.5
—
0
5
46
471
0.97
0.03
2.5
4.3
1.0
1.0
kg/l
—
9
60
12
112
1.08
0.03
4.2
3.1
—
—
—
0
0
12
128
0.93
0.02
2.6
4.7
—
—
—
0
0
26
269
0.96
0.02
1.7
1.3
—
—
—
0
0
14
148
0.94
0.02
3.0
5.8
—
—
—
0
0
14
148
0.94
0.02
2.4
2.7
—
—
—
0
0
16
168
0.95
0.02
4.0
4.2
0.0
0.0
%
—
5
33
83
839
0.98
0.02
3.0
3.6
—
—
—
0
0
17
177
0.96
0.01
4.0
4.2
0.0
0.2
%
—
6
45
18
187
0.96
0.01
3.9
4.1
0.7
1.1
%
—
7
51
31
303
1.03
0.01
2.5
1.7
27.7
29.5
s
1.92
31
290
27
268
1.01
0.00
1.5
2.0
96.3
120.4
ug/g
0.29
18
212
15
151
0.99
0.00
4.7
2.4
—
—
—
0
0
17
169
1.01
0.00
4.1
2.5
67.6
67.3
g/l
0.04
17
156
24
239
1.00
0.00
3.8
5.0
104.3
103.8
mmol/l
0.21
24
232
90
899
1.00
0.00
2.4
2.6
137.3
94.7
ug/l
0.74
81
811
31
313
0.99
0.00
1.2
1.3
510.0
699.0
titre
—
8
84
11
113
0.97
0.00
1.5
1.2
—
—
—
0
0
17
173
0.98
0.00
1.6
1.3
—
—
—
0
0
19
187
1.02
0.00
1.6
1.3
—
—
—
0
0
12
124
0.97
0.00
4.3
7.3
26.2
25.3
mmol/l
0.39
12
118
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
0.2
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
20.7
—
2496.3
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
102.7
—
0
6
7
78
0.89
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
18.5
—
1121.3
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
5
58
0.86
0.00
2.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
8
89
0.90
0.00
2.6
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
69
1.01
0.00
1.1
1.4
—
—
—
0
0
5
50
1.00
0.00
4.2
2.5
1.9
1.5
mg/l
—
5
43
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
124.1
—
0
9

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_BREAST_LOBULAR – Carcinoma in situ of breast, lobular

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).