Thyroiditis

THYROIDITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2952

6. Filter based on genotype QC (FinnGen only)

2851

Control definitions (FinnGen only)

Control exclude
THYROID_DISORDER_IBD

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19571 15459 3979
Only index persons 17896 14316 3580
Unadjusted period prevalence (%)
Whole population 0.37 0.44 0.11
Only index persons 0.45 0.53 0.14
Median age at first event (years)
Whole population 45.67 45.04 48.17
Only index persons 44.76 44.12 47.30

-FinnGen-

Key figures

All Female Male
Number of individuals 2851 2356 495
Unadjusted period prevalence (%) 0.73 0.84 0.23
Median age at first event (years) 46.23 45.33 50.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2952
Matched controls
29520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H03AA01
ATC
levothyroxine sodium; systemic
5.6
307.7
1566
4960
E06.3
ICD-10 Finland
Autoimmune thyroiditis
279.2
307.7
719
34
H03BB01
ATC
carbimazole; oral
119.0
307.7
471
47
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
367.6
307.7
327
10
E06.9
ICD-10 Finland
Thyroiditis, unspecified
601.4
307.7
460
9
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
307.7
1205
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
1543.9
290.3
278
*
104
Kela drug reimbursment
Thyroid insufficiency
6.0
278.3
558
1099
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
10.5
259.7
299
313
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
4.0
222.3
802
2514
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
47.8
181.4
106
23
E06.0
ICD-10 Finland
Acute thyroiditis
928.3
180.2
175
*
H02AB06
ATC
prednisolone; systemic
2.6
137.9
1741
10485
2451A
ICD-9 Finland
Thyroiditis, Subacute thyroiditis
+∞
135.5
129
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
9.7
119.7
142
153
BAA60
NOMESCO Finland
Total thyroidectomy
7.5
115.4
169
236
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
9.2
114.2
141
160
24509
ICD-8 Finland
Thyroiditis, Unspecified
+∞
113.3
108
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.9
90.3
291
814
E06.4
ICD-10 Finland
Drug-induced thyroiditis
+∞
89.0
85
*
E03
ICD-10 Finland
Other hypothyroidism
3.5
87.0
329
1024
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.3
86.4
236
585
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
831.2
82.9
81
*
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
36.3
79.9
50
14
24500
ICD-8 Finland
Thyroiditis, Subacuta de Quervain
+∞
77.4
74
*
C07AA05
ATC
propranolol; systemic
2.3
76.8
801
4178
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
28.8
76.0
51
18
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
70.1
67
*
H02AB07
ATC
prednisone; oral
2.4
61.6
515
2421
2459X
ICD-9 Finland
Thyroiditis, unspecified
+∞
58.5
56
*
T86
ICPC
Hypothyroidism/myxoedema
3.4
56.5
214
662
T85
ICPC
Hyperthyroidism/thyrotoxicosis
13.9
56.2
52
38
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
3.6
54.4
188
548
2452A
ICD-9 Finland
Thyroiditis, Chronic lymphocytic thyroiditis
+∞
53.3
51
*
E06
ICD-10 Finland
Thyroiditis
112.1
50.9
55
5
C01BD01
ATC
amiodarone; systemic
5.4
50.4
101
193
24503
ICD-8 Finland
Thyroiditis, Chronica
+∞
50.1
48
*
24501
ICD-8 Finland
Thyroiditis, Subacuta alia
+∞
49.1
47
*
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
159.1
44.9
47
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
4.9
42.6
96
203
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
42.0
1195
8385
BA1AE, ,
SPAT
5.7
41.5
77
137
A02BC02
ATC
pantoprazole; systemic
1.7
41.3
2029
16451
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
5.1
41.2
87
174
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
40.7
39
*
R07.0
ICD-10 Finland
Pain in throat
2.5
40.3
281
1207
R53
ICD-10 Finland
Malaise and fatigue
1.8
38.2
774
4908
C07AB07
ATC
bisoprolol; oral
1.6
35.7
1256
9197
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
35.6
807
5269
H062, E050,
ICD-10 Finland
+∞
34.4
33
*
R50.9
ICD-10 Finland
Fever, unspecified
1.9
32.7
449
2508
A02BC05
ATC
esomeprazole; systemic
1.6
32.1
1219
9023
R21
ICPC
Throat symptom/complaint
1.7
31.8
705
4552
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
4.1
31.3
88
222
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
3.5
29.9
105
309
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
29.5
803
5457
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
4.5
28.5
70
159
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
3.5
28.3
98
286
R51.80
ICD-10 Finland
Headache
1.8
27.9
531
3271
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
27.3
136
493
G44.2
ICD-10 Finland
Tension-type headache
1.8
27.1
473
2838
R06.0
ICD-10 Finland
Dyspnoea
1.6
26.6
746
5086
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
26.3
809
5637
E03.82
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
22.8
25.2
36
16
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
5.5
23.8
46
85
N03AX16
ATC
[U] pregabalin
1.6
23.5
669
4558
EP1AE, ,
SPAT
3.3
23.3
90
282
A02BC03
ATC
lansoprazole; oral
1.6
23.2
807
5758
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
23.0
1172
9054
R00.2
ICD-10 Finland
Palpitations
2.0
22.9
268
1411
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.3
22.6
180
817
E03.8
ICD-10 Finland
Other specified hypothyroidism
8.8
22.4
28
32
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
22.4
950
7063
M79.6
ICD-10 Finland
Pain in limb
1.5
22.0
1228
9638
R52.9
ICD-10 Finland
Pain, unspecified
1.9
21.2
292
1623
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
21.1
644
4445
M54.5
ICD-10 Finland
Low back pain
1.5
20.9
1053
8077
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
20.6
1489
12214
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
211.4
20.6
21
*
R03AC02
ATC
salbutamol; inhalant
1.4
20.4
1620
13515
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
20.1
816
5982
UJF32
NOMESCO Finland
Coloscopy
1.5
19.6
678
4803
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
5.8
19.3
35
61
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
19.0
354
2153
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
18.9
532
3593
A03
ICPC
Fever
1.6
18.8
497
3308
N03AX12
ATC
[U] gabapentin; oral
1.6
18.4
465
3061
E06.5
ICD-10 Finland
Other chronic thyroiditis
33.1
18.0
23
7
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
17.9
364
2265
R42
ICD-10 Finland
Dizziness and giddiness
1.5
17.7
607
4281
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
17.6
769
5700
J01AA02
ATC
doxycycline; systemic
1.5
17.4
2210
19782
M25.5
ICD-10 Finland
Pain in joint
1.4
17.4
942
7268
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
17.2
345
2138
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
17.1
512
3500
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.2
17.1
68
217
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
17.1
518
3553
K30
ICD-10 Finland
Functional dyspepsia
1.7
17.1
337
2080
N02AX02
ATC
tramadol; systemic, rectal
1.4
16.9
1116
8902
J02AC01
ATC
fluconazole; systemic
1.4
16.8
1281
10470
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.8
16.6
84
308
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
14.3
16.3
27
19
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
16.3
185
963
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.4
16.1
115
498
J01FA10
ATC
azithromycin; systemic
1.4
16.0
1692
14551
P01AB01
ATC
metronidazole; oral, rectal
1.4
15.8
1185
9627
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
15.8
712
5290
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
15.7
529
3707
N06AX11
ATC
mirtazapine; oral
1.4
15.6
936
7324
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
3.9
15.3
45
118
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
15.2
491
3406
A02BC01
ATC
omeprazole; systemic
1.4
15.1
724
5435
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
20.1
15.1
22
11
J01DB01
ATC
cefalexin; oral
1.5
15.1
2360
21575
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
6.5
14.9
24
37
J01MA02
ATC
ciprofloxacin; systemic
1.4
14.8
968
7665
A04
ICPC
Weakness/tiredness general
1.6
14.8
400
2666
24409
ICD-8 Finland
Myxoedema, (hypothyreosis) NUD
11.9
14.5
26
22
L17
ICPC
Foot/toe symptom/complaint
1.4
14.4
773
5913
J01DA01
ATC
[U] cefalexin
1.4
14.4
1722
14978
J01FA06
ATC
roxithromycin; oral
1.4
14.4
1114
9060
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
14.3
457
3162
M03BX02
ATC
tizanidine; oral
1.4
14.2
1777
15550
N02BE01
ATC
paracetamol; systemic, rectal
1.5
13.9
2550
23772
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
13.7
398
2693
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
13.7
346
2267
M79.7
ICD-10 Finland
Fibromyalgia
2.1
13.7
125
600
R01AD09
ATC
mometasone; nasal
1.3
13.7
1320
11079
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
13.5
13
*
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
13.5
277
1725
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
13.4
506
3618
C07AB02
ATC
metoprolol; systemic
1.5
13.4
448
3125
207
Kela drug reimbursment
Chronic arrhythmias
1.6
13.4
299
1902
R06AX27
ATC
desloratadine; oral
1.4
13.2
850
6688
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
13.2
2056
18493
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
12.8
253
1559
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
12.8
279
1765
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.1
12.8
115
550
M79.1
ICD-10 Finland
Myalgia
1.5
12.7
426
2971
R51
ICD-10 Finland
Headache
1.9
12.7
168
921
L02
ICPC
Back symptom/complaint
1.6
12.6
289
1849
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
12.5
376
2562
K80
ICPC
Cardiac arrhythmia NOS
1.7
12.5
213
1260
H03BA02
ATC
propylthiouracil; oral
+∞
12.5
12
*
N06AX21
ATC
duloxetine; oral
1.6
12.5
340
2267
R74
ICPC
Upper respiratory infection acute
1.4
12.4
928
7464
N01
ICPC
Headache
1.6
12.4
331
2198
D01
ICPC
Abdominal pain/cramps general
1.6
12.3
335
2232
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.8
12.2
171
954
TFP20
NOMESCO Finland
Cardiodefibrillation
2.0
12.1
140
733
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
12.4
12.1
21
17
H04AA01
ATC
glucagon; nasal, parenteral
2.7
12.1
65
247
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
12.0
1161
9689
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.9
11.9
148
795
D06
ICPC
Abdominal pain localized other
1.7
11.9
248
1550
A10AB01
ATC
insulin (human); parenteral
2.3
11.9
89
395
R03DC03
ATC
montelukast; oral
1.5
11.9
475
3431
Z71.8
ICD-10 Finland
Other specified counselling
1.4
11.8
855
6830
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
11.8
336
2262
R13
ICD-10 Finland
Dysphagia
1.8
11.8
176
1002
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
11.7
736
5750
XF404
NOMESCO Finland
Ambulatory ECG
1.7
11.7
200
1184
A10AB04
ATC
insulin lispro; parenteral
2.3
11.7
87
385
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
4.9
11.7
25
51
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
11.5
225
1382
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
11.5
638
4884
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
3.7
11.4
35
95
H57.1
ICD-10 Finland
Ocular pain
2.0
11.4
114
568
R01AD08
ATC
fluticasone; nasal
1.4
11.4
805
6404
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
11.1
815
6512
L01
ICPC
Neck symptom/complaint
1.5
11.1
444
3202
D11
ICPC
Diarrhoea
1.5
11.1
331
2251
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.7
11.1
222
1373
XKD00
NOMESCO Finland
Uroflowmetry
1.7
11.0
215
1321
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.0
11.0
48
163
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.0
11.0
124
645
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
11.0
1301
11123
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.7
10.9
58
219
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
10.9
239
1512
N05CF01
ATC
zopiclone; oral
1.3
10.9
808
6468
A10AA01, ,
ATC
2.5
10.8
68
279
R06AE07
ATC
cetirizine; oral
1.3
10.8
1260
10745
A02BC04
ATC
rabeprazole; oral
1.6
10.7
251
1614
SPAT1263
SPAT
Sampling
1.3
10.7
1105
9263
R01AD58
ATC
fluticasone, combinations; nasal
1.4
10.6
707
5562
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
10.6
498
3698
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
4.1
10.6
28
68
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.1
10.6
103
508
A11
ICPC
Chest pain NOS
1.7
10.5
199
1212
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.0
10.5
119
620
J01
ICD-10 Finland
Acute sinusitis
1.8
10.5
170
992
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
10.5
738
5855
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
10.4
159
911
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
10.4
545
4122
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.5
10.4
62
248
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
10.4
343
2380
Z01.7
ICD-10 Finland
Laboratory examination
1.5
10.4
380
2695
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.8
10.3
52
191
R03BA01
ATC
beclometasone; inhalant
1.5
10.3
367
2588
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
10.3
265
1744
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.0
10.2
45
154
D02
ICPC
Abdominal pain epigastric
1.7
10.2
174
1031
H05.2
ICD-10 Finland
Exophthalmic conditions
13.1
10.1
17
13
T81
ICPC
Goitre
5.3
10.1
20
38
C01BC04
ATC
flecainide; systemic
2.2
10.1
79
358
SPAT1097
SPAT
Recording of ECG
1.5
10.1
330
2287
2448A
ICD-9 Finland
Acquired hypothyroidism, Other specified acquired hypothyroidism[HYPOTHYREOSIS POST THYREOIDITIDEM]
14.6
10.0
16
11
R60.0
ICD-10 Finland
Localized oedema
1.5
10.0
283
1902
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.6
10.0
222
1410
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
10.0
369
2620
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
3.7
10.0
31
85
XF402
NOMESCO Finland
ECG with work load test
1.6
9.9
227
1452
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.9
605
4690
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
3.6
9.8
31
86
SPAT1301
SPAT
No procedures
1.3
9.8
769
6190
XQ800
NOMESCO Finland
Prick test
1.6
9.8
222
1418
N30.0
ICD-10 Finland
Acute cystitis
1.4
9.7
464
3451
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
1.8
9.7
154
893
M54.2
ICD-10 Finland
Cervicalgia
1.6
9.7
215
1364
A01AB09
ATC
miconazole; local oral
1.6
9.7
217
1382
M54
ICD-10 Finland
Dorsalgia
1.5
9.7
335
2349
H92.0
ICD-10 Finland
Otalgia
1.7
9.6
171
1024
R05
ICPC
Cough
1.3
9.6
642
5044
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
9.6
339
2385
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
9.5
591
4592
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.5
1158
9881
A02BA02
ATC
ranitidine; systemic
1.4
9.4
455
3392
UKC02
NOMESCO Finland
Cystoscopy
1.5
9.4
289
1977
2450A
ICD-9 Finland
Thyroiditis, Acute thyroiditis
+∞
9.4
9
*
2458X
ICD-9 Finland
Thyroiditis, Other and unspecified chronic thyroiditis
+∞
9.4
9
*
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
9.4
9
*
A10AA02, ,
ATC
2.2
9.3
74
338
L80
ICD-10 Finland
Vitiligo
4.7
9.3
21
45
C10AA07
ATC
rosuvastatin; oral
1.3
9.3
746
6018
J01FA09
ATC
clarithromycin; systemic
1.3
9.3
846
6944
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
9.3
203
1285
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
9.2
633
4989
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
9.2
457
3424
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
9.2
170
1031
SFA20
NOMESCO Finland
Two-surface restoration
1.3
9.1
1610
14339
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
1.9
9.1
106
558
A10AC01
ATC
insulin (human); parenteral
1.7
9.1
171
1040
H02AB04
ATC
methylprednisolone; systemic
1.4
9.1
369
2667
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
9.1
508
3880
C09CA06
ATC
candesartan; oral
1.3
9.1
587
4586
I49.1
ICD-10 Finland
Atrial premature depolarization
2.0
9.0
94
476
K02.1
ICD-10 Finland
Caries of dentine
1.3
9.0
1604
14291
Z01.2
ICD-10 Finland
Dental examination
1.3
9.0
1241
10728
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
9.0
423
3139
C07AA07
ATC
sotalol; systemic
2.2
9.0
71
324
A03FA02
ATC
cisapride; oral, rectal
1.6
8.9
182
1131
R05
ICD-10 Finland
Cough
1.4
8.9
553
4290
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
8.9
1974
18055
L03
ICPC
Low back symptom/complaint
1.3
8.9
744
6031
M54.3
ICD-10 Finland
Sciatica
1.7
8.8
155
927
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.5
8.8
53
214
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
8.8
1040
8815
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
8.8
193
1223
ZXA10
NOMESCO Finland
Bilateral
1.4
8.8
437
3272
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
8.7
260
1766
D10
ICPC
Vomiting
1.7
8.7
165
1006
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
8.7
337
2412
M01AH05
ATC
etoricoxib; oral
1.3
8.7
1682
15110
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
8.6
517
3987
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
4.0
8.6
24
61
J01FF01
ATC
clindamycin; systemic
1.3
8.6
669
5367
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
8.6
289
2015
H02AB09
ATC
hydrocortisone; systemic
2.3
8.5
65
292
M70.6
ICD-10 Finland
Trochanteric bursitis
1.4
8.5
364
2654
XCK00
NOMESCO Finland
Perimetry
1.7
8.5
140
822
B34.9
ICD-10 Finland
Viral infection, unspecified
2.1
8.5
76
365
H3603, E103,
ICD-10 Finland
3.6
8.4
27
76
H3600, E103,
ICD-10 Finland
3.1
8.4
34
111
N05AH04
ATC
quetiapine; oral
1.4
8.4
446
3376
J01CA04
ATC
amoxicillin; systemic
1.3
8.4
2311
21633
J45.1
ICD-10 Finland
Nonallergic asthma
1.6
8.3
177
1112
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
8.3
8
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.6
8.3
197
1271
A01
ICPC
Pain general/multiple sites
1.5
8.2
238
1606
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
8.2
813
6724
A07AA02
ATC
nystatin; oral
1.7
8.2
139
823
SPAT1283
SPAT
Restricted health certificate
1.4
8.2
484
3723
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
8.2
206
1348
J01MA12
ATC
levofloxacin; systemic
1.4
8.2
403
3010
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
8.2
1090
9351
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
8.2
956
8076
A05
ICPC
Feeling ill
1.7
8.1
158
972
E0000UV, ,
ATC
1.3
8.1
1105
9504
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.0
8.1
85
433
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.5
8.1
224
1499
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
2.7
8.1
42
158
R49.01
ICD-10 Finland
Functional dysphonia
2.0
8.0
89
462
J35.0
ICD-10 Finland
Chronic tonsillitis
1.7
8.0
149
905
Z00.0
ICD-10 Finland
General medical examination
1.4
8.0
464
3560
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
3.3
7.9
29
89
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
7.9
612
4896
B01AF02
ATC
apixaban; oral
1.5
7.9
238
1622
ZX120
NOMESCO Finland
Intravenous
1.5
7.9
216
1442
6481B
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Thyroid dysfunction[HYPOTHYREOSIS IN GRAVIDITATE]
13.1
7.9
13
10
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.7
7.9
152
933
R03AC03
ATC
terbutaline; inhalant
1.4
7.8
363
2683
TFP34
NOMESCO Finland
Electrophysiological investigation
2.1
7.8
73
356
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.8
7.8
124
721
R02
ICPC
Shortness of breath/dyspnoea
1.4
7.8
303
2171
A29
ICPC
General symptom/complaint other
1.4
7.8
297
2121
M01AB05
ATC
diclofenac; systemic, rectal
1.2
7.7
1777
16170
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
7.7
202
1334
Z71.9
ICD-10 Finland
Counselling, unspecified
1.6
7.7
181
1166
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
45.1
7.7
9
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
3.5
7.7
25
71
2504
FHL
Unilateral resection or enucleation
3.4
7.7
26
76
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
3.0
7.6
32
107
A10AB05
ATC
insulin aspart; parenteral
1.6
7.6
160
1004
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
8.0
7.6
16
20
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
7.6
144
881
ZXH06, ,
SPAT
1.8
7.5
111
632
R03BA02
ATC
budesonide; inhalant
1.3
7.5
465
3599
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.5
899
7600
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
7.5
871
7336
K04
ICPC
Palpitations/awareness of heart
1.7
7.5
137
830
L04
ICPC
Chest symptom/complaint
1.6
7.5
159
1001
M01AE02
ATC
naproxen; oral, rectal
1.2
7.5
1549
13915
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.5
7.4
210
1411
N76.0
ICD-10 Finland
Acute vaginitis
1.5
7.4
197
1306
J01EA01
ATC
trimethoprim; systemic
1.3
7.4
733
6053
ZXE00
NOMESCO Finland
One hour or less
1.3
7.4
996
8531
N05BA04
ATC
oxazepam; oral
1.3
7.4
664
5415
S18
ICPC
Laceration/cut
1.2
7.4
1098
9512
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.8
7.3
100
556
TFP35
NOMESCO Finland
Electroanatomical mapping
2.7
7.3
37
137
24502
ICD-8 Finland
Thyroiditis, Subchronica
+∞
7.3
7
*
R07.3
ICD-10 Finland
Other chest pain
1.5
7.3
243
1690
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
7.3
254
1782
R60.9
ICD-10 Finland
Oedema, unspecified
1.7
7.3
124
737
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
2.5
7.2
43
173
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.6
7.2
158
1001
N80.0
ICD-10 Finland
Endometriosis of uterus
2.1
7.2
66
320
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.5
7.2
228
1569
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
7.2
1074
9299
R83
ICPC
Respiratory infection other
1.3
7.2
700
5766
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
30.1
7.1
9
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
2.7
7.1
36
134
K08.80
ICD-10 Finland
Toothache NOS
1.5
7.1
239
1668
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
7.0
1479
13270
H53.1
ICD-10 Finland
Subjective visual disturbances
1.6
7.0
169
1096
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.7
7.0
130
790
T89
ICPC
Diabetes insulin dependent
1.8
7.0
91
499
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.0
875
7421
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
6.9
539
4310
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
6.9
121
725
R39.1
ICD-10 Finland
Other difficulties with micturition
2.2
6.9
57
266
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
2.3
6.9
50
221
R12
ICD-10 Finland
Heartburn
1.5
6.9
198
1337
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.6
6.8
136
842
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.6
6.8
141
881
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
6.8
866
7351
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.3
6.8
48
209
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
6.8
143
897
UJD02
NOMESCO Finland
Gastroscopy
1.8
6.8
107
621
R52.2
ICD-10 Finland
Other chronic pain
1.8
6.8
97
547
B01AA03
ATC
warfarin; systemic
1.4
6.8
314
2318
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.4
6.8
289
2103
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
6.8
258
1840
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.7
6.8
113
668
N64.4
ICD-10 Finland
Mastodynia
1.8
6.8
98
556
R11
ICD-10 Finland
Nausea and vomiting
1.5
6.8
216
1490
N06AB10
ATC
escitalopram; oral
1.3
6.7
549
4415
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
6.7
260
1861
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
6.7
924
7914
R49.08
ICD-10 Finland
Other specified dysphonia
2.1
6.7
61
296
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.5
6.7
209
1436
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.6
6.7
166
1086
R20.2
ICD-10 Finland
Paraesthesia of skin
1.5
6.6
176
1167
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
4.0
6.6
18
45
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
5.9
6.6
17
29
H01
ICPC
Ear pain/earache
1.4
6.6
293
2151
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.6
6.6
147
938
M35.3
ICD-10 Finland
Polymyalgia rheumatica
1.9
6.5
82
445
J45
ICD-10 Finland
Asthma
1.4
6.5
265
1913
A10AE05
ATC
insulin detemir; parenteral
1.7
6.5
115
690
XA420
NOMESCO Finland
Extensive sleep examination
3.0
6.5
27
90
M35.7
ICD-10 Finland
Hypermobility syndrome
2.3
6.5
48
214
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.5
6.5
177
1182
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
6.5
159
1037
SFA10
NOMESCO Finland
One-surface restoration
1.2
6.5
1460
13151
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
6.4
297
2193
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
2.7
6.4
32
118
C10AA05
ATC
atorvastatin; oral
1.2
6.4
871
7442
TEA00
NOMESCO Finland
Biopsy of lip
2.8
6.4
30
107
E07.89
ICD-10 Finland
Other specified disorders of thyroid
14.3
6.4
10
7
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.5
6.4
170
1129
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.3
6.4
46
203
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
6.3
353
2688
J37.0
ICD-10 Finland
Chronic laryngitis
1.9
6.3
81
443
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
6.0
6.3
16
27
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
6.3
596
4883
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
6.3
206
1429
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
6.3
746
6279
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
3.8
6.3
18
47
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
6.3
6
*
L16
ICPC
Ankle symptom/complaint
1.4
6.2
292
2161
WZC00, ,
SPAT
1.4
6.2
236
1683
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
6.2
207
1440
R31
ICD-10 Finland
Unspecified haematuria
1.5
6.2
164
1087
G47.3
ICD-10 Finland
Sleep apnoea
1.3
6.2
468
3721
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.4
6.2
234
1667
L50.9
ICD-10 Finland
Urticaria, unspecified
1.8
6.2
96
556
M02AA07
ATC
piroxicam; topical
1.2
6.2
869
7445
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.2
6.2
51
238
K29.4
ICD-10 Finland
Chronic atrophic gastritis
2.3
6.2
43
187
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.1
6.2
24
77
R01AD01
ATC
beclometasone; nasal
1.3
6.1
391
3037
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
6.1
324
2446
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
6.1
1370
12301
H02
ICPC
Hearing complaint
1.4
6.1
277
2042
L11
ICPC
Wrist symptom/complaint
1.4
6.1
231
1650
N89
ICPC
Migraine
1.7
6.1
101
598
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
8.6
6.0
12
14
G50.1
ICD-10 Finland
Atypical facial pain
2.1
6.0
53
254

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
527
369
17.17
307.65
2.1
1.1
3.57
2.28
iu/l
1.98
205
83
838
1966
5.56
307.65
1.5
1.2
223.11
158.19
iu/ml
2.92
416
724
794
1444
7.15
307.65
4.4
2.3
4.62
4.40
pmol/l
4.10
720
1257
2672
20274
4.35
135.30
9.1
3.9
15.36
14.59
pmol/l
36.37
2559
18641
2758
23564
3.59
71.41
10.3
4.7
1.90
2.08
mu/l
0.77
2638
21860
2317
18473
2.18
65.24
5.3
4.0
12.53
11.55
mm/h
2.74
2190
17189
1575
11512
1.79
51.07
6.8
6.2
1.22
1.22
mmol/l
0.32
1353
9830
1857
14272
1.81
50.57
8.9
8.9
3.99
3.99
e9/l
0.02
1656
12508
1549
11569
1.71
43.83
6.4
6.2
—
—
—
0
0
2234
18605
1.83
41.69
7.8
7.3
75.02
76.70
u/l
0.88
2121
17525
1407
10380
1.68
40.49
6.2
5.5
1.22
1.22
mmol/l
0.02
1287
9481
1604
12317
1.66
38.95
6.0
5.8
0.56
0.56
e9/l
0.11
1415
10734
1653
12795
1.66
38.88
6.3
6.0
0.18
0.19
e9/l
0.25
1485
11310
1605
12342
1.66
38.63
6.0
5.8
0.04
0.04
e9/l
0.68
1414
10739
1642
12701
1.66
38.61
6.1
5.8
1.96
1.95
e9/l
0.10
1493
11331
445
2349
2.05
38.56
2.2
2.1
388.26
373.83
nmol/l
0.85
406
2149
1740
13712
1.66
37.57
4.8
4.4
6.55
6.55
mmol/l
0.06
1648
12715
995
6849
1.68
36.18
4.0
3.8
7.40
7.40
ph
0.08
173
1291
2749
25027
2.43
33.84
16.5
12.7
19.44
21.38
mg/l
2.87
2332
19570
1457
11181
1.60
33.39
6.3
5.9
0.68
0.69
%
0.09
1350
10434
1502
11632
1.59
32.95
6.6
6.1
8.39
8.29
%
0.57
1404
10915
1540
11999
1.59
32.90
6.4
5.9
29.26
28.71
%
1.17
1443
11289
1492
11556
1.59
32.56
6.3
5.9
2.81
2.80
%
0.03
1388
10820
1519
11839
1.58
32.09
6.2
5.7
56.13
56.76
%
1.25
1423
11117
975
6852
1.63
31.76
2.3
2.1
122.77
193.23
u/l
3.98
924
6462
95
255
3.82
30.99
2.6
4.6
158.41
76.68
u/ml
0.45
32
82
728
4786
1.69
30.54
1.3
1.3
24.25
30.30
iu/ml
0.86
232
1581
1564
12372
1.56
30.22
5.6
6.0
9.82
10.59
umol/l
3.48
1487
11720
1136
8368
1.58
29.97
3.8
3.3
27.70
38.18
ng/l
0.91
676
5140
879
6095
1.63
29.84
1.4
1.3
1.85
1.51
u/ml
0.27
237
1653
1381
10652
1.56
29.65
2.5
2.3
78.36
77.24
nmol/l
0.79
1270
9689
2742
25217
2.23
28.13
17.3
13.9
139.57
139.66
mmol/l
1.17
2704
24568
578
3644
1.73
27.98
1.5
1.3
523.33
564.05
titre
0.19
144
770
2745
25293
2.22
27.40
17.4
14.1
3.93
3.94
mmol/l
0.25
2700
24593
762
5209
1.62
26.92
1.5
1.4
2.13
2.26
g/l
1.57
446
3202
1296
10055
1.52
25.86
14.2
12.3
1.18
1.18
inr
0.09
403
2992
1093
8179
1.53
25.84
3.0
3.3
2.35
2.36
mmol/l
1.80
959
7273
1468
11706
1.51
25.57
3.4
2.8
107.24
97.22
ug/l
0.73
1357
10951
803
5635
1.58
25.14
1.8
1.7
0.87
1.07
mg/l
1.91
603
4254
1016
7529
1.53
24.89
2.6
2.5
54.99
58.59
u/l
1.77
942
6959
1274
10023
1.48
22.77
4.3
4.6
36.15
35.95
g/l
0.67
1175
9327
803
5759
1.54
22.38
3.2
2.8
1045.52
1135.25
ng/l
0.29
684
4837
664
4581
1.58
21.91
1.4
1.3
7.85
10.74
u/ml
0.81
271
1834
148
628
2.43
21.63
1.3
1.2
—
—
—
0
0
1990
17244
1.47
20.53
4.8
4.3
—
—
—
0
0
290
1631
1.86
20.26
2.4
1.7
—
—
—
0
0
1935
16737
1.45
19.67
4.0
3.4
—
—
—
0
0
1506
12465
1.43
19.36
4.0
3.6
0.00
0.00
estimate
1.08
249
2272
1245
9965
1.43
19.25
3.7
3.3
5.89
5.87
ph
0.08
96
822
1490
12321
1.42
19.18
4.0
3.6
0.00
0.00
estimate
1.23
271
2447
1918
16629
1.44
18.75
4.9
4.4
2194.50
2366.00
e6/l
0.04
34
205
2789
26317
2.08
18.74
17.8
14.4
72.27
71.43
umol/l
0.89
2789
26311
1487
12341
1.41
18.47
5.2
4.9
0.00
0.00
estimate
0.80
250
2306
295
1734
1.78
17.77
3.2
3.6
78.47
83.31
ng/l
0.46
256
1491
527
3606
1.56
17.60
3.4
3.4
0.83
0.82
mmol/l
1.57
494
3389
2792
26457
2.02
16.93
11.9
9.9
24.70
24.83
u/l
0.17
2723
25585
596
4225
1.51
16.86
4.3
3.4
121.05
375.48
ng/l
3.69
389
2964
203
1084
1.94
16.57
1.3
1.3
0.81
1.59
u/ml
0.59
28
86
795
6011
1.44
16.12
2.4
2.2
2.62
2.90
mg/l
2.79
680
5141
97
395
2.51
15.55
1.5
1.7
0.72
0.75
g/l
0.09
76
298
300
1845
1.70
15.34
2.6
2.7
10.46
10.45
g/l
0.01
269
1688
2415
22175
1.49
15.12
5.9
5.3
39.40
39.00
mmol/mol
1.26
2266
20668
2760
26172
1.84
14.94
15.2
11.8
—
—
—
0
0
816
6281
1.41
14.75
6.8
6.6
—
—
—
0
0
1047
8409
1.38
14.69
3.7
3.5
67.21
89.09
e6/l
0.71
750
5692
714
5373
1.43
14.63
4.3
4.0
1.02
1.02
kg/l
0.64
101
767
447
3072
1.54
14.42
1.6
1.5
—
—
—
0
0
1319
11019
1.36
14.31
9.7
8.8
0.00
0.00
e9/l
0.44
1077
9011
1017
8157
1.38
14.29
3.3
3.2
29.71
31.14
u/l
0.70
980
7769
474
3325
1.51
13.85
2.1
2.3
98.66
113.48
ug/g
0.45
358
2607
659
4937
1.43
13.71
1.6
1.6
15631335.97
40352580.81
pmol/l
0.75
531
4146
132
649
2.08
13.60
2.3
2.0
11.00
11.35
mg/l
0.16
122
603
494
3533
1.48
13.07
2.6
2.3
13.42
13.51
umol/l
0.09
451
3291
967
7782
1.36
13.02
3.0
3.0
—
—
—
0
0
875
6932
1.37
13.01
3.0
3.1
74.57
81.60
e6/l
0.08
685
5236
581
4299
1.44
12.84
2.7
2.9
2.43
2.45
mmol/l
2.79
503
3780
452
3206
1.48
12.42
2.5
2.3
2.41
2.39
g/l
0.46
411
2973
1137
9430
1.33
12.37
2.0
1.9
98.92
97.44
pmol/l
0.43
580
4738
170
944
1.85
12.33
1.5
1.5
15.24
10.13
u/ml
—
7
22
237
1451
1.69
12.29
1.8
1.8
1.29
1.42
g/l
0.49
214
1329
2551
23915
1.49
12.17
4.6
4.2
5.78
5.80
mmol/l
0.34
2375
22003
263
1667
1.63
11.92
1.4
1.3
32.14
47.15
au/ml
0.58
14
97
283
1829
1.61
11.85
2.5
2.4
13.56
25.67
au/ml
2.48
27
151
151
819
1.89
11.80
1.8
1.8
0.22
0.23
g/l
0.68
143
769
268
1719
1.61
11.58
2.4
2.7
67.31
66.81
g/l
0.57
242
1573
118
594
2.03
11.46
1.3
1.2
35.81
43.49
u/ml
0.21
14
73
418
2966
1.48
11.41
2.7
2.4
22.84
23.01
%
0.08
339
2542
398
2799
1.49
11.36
5.0
5.6
1.03
1.04
mmol/l
0.40
376
2593
822
6566
1.35
11.29
4.4
4.0
0.00
0.00
estimate
1.70
250
2285
143
775
1.89
11.21
1.4
1.2
7.79
34.86
u/ml
1.83
11
49
628
4817
1.39
11.12
2.4
2.5
7.03
7.05
e6/l
0.01
555
4302
153
852
1.84
11.02
1.8
1.7
1.17
1.18
g/l
0.16
145
804
786
6263
1.35
10.90
2.8
2.9
—
—
—
0
0
798
6377
1.34
10.85
2.9
3.0
0.28
0.42
e6/l
1.80
620
4784
735
5812
1.35
10.69
4.0
3.6
—
—
—
0
0
719
5677
1.35
10.54
4.5
4.1
—
—
—
0
0
297
1999
1.54
10.41
1.5
1.4
—
—
—
0
0
320
2192
1.52
10.34
1.2
1.2
—
—
—
0
0
223
1407
1.63
10.30
2.1
2.4
—
—
—
0
0
212
1326
1.65
10.14
1.1
1.1
172.00
114.70
titre
—
5
30
2355
21946
1.36
9.99
19.0
15.1
14.62
14.74
%
0.48
2325
21561
46
162
2.87
9.91
4.1
6.6
—
—
—
0
0
144
820
1.79
9.68
1.2
1.2
—
—
—
0
0
61
252
2.45
9.61
1.5
1.5
0.29
0.43
g/l
3.59
46
176
61
252
2.45
9.61
1.5
1.5
2.79
2.90
g/l
0.24
46
176
61
253
2.44
9.54
1.5
1.5
6.37
6.85
g/l
0.52
45
177
741
5953
1.33
9.52
2.3
2.4
1589.35
4589.30
umol/l
2.92
643
5277
248
1642
1.56
9.36
2.8
2.8
138.82
172.43
ng/l
1.04
228
1480
582
4537
1.35
9.12
2.7
2.8
506.50
529.87
mosm/kgh2o
1.60
484
3904
844
6943
1.30
9.06
3.4
3.1
7.09
7.17
mmol/l
0.21
737
5918
506
3866
1.37
9.00
2.6
2.6
1.00
1.39
e6/l
1.12
301
2150
578
4514
1.35
8.93
1.7
1.6
—
—
—
0
0
2863
27870
1.90
8.39
24.8
18.8
39.94
39.78
%
0.85
2706
26287
2866
27912
1.92
8.33
24.7
18.7
90.51
90.76
fl
2.43
2847
27561
59
257
2.32
8.32
1.6
1.5
—
—
—
0
0
2865
27901
1.91
8.30
24.8
18.8
263.07
260.10
e9/l
1.75
2822
27244
2866
27915
1.92
8.28
24.6
18.7
30.09
30.17
pg
2.14
2847
27562
2867
27928
1.92
8.28
24.9
18.9
133.62
133.74
g/l
0.19
2847
27570
2866
27919
1.91
8.22
24.8
18.8
4.46
4.46
e12/l
0.31
2819
27193
455
3470
1.37
8.14
1.2
1.2
—
—
—
0
0
74
358
2.09
8.09
1.4
1.5
—
—
—
0
0
660
5321
1.31
8.09
1.9
1.9
—
—
—
0
0
230
1548
1.53
8.07
3.5
3.0
4.42
4.64
kpa
1.20
223
1500
2865
27916
1.89
8.06
24.8
18.8
6.66
6.65
e9/l
0.06
2819
27183
257
1772
1.49
8.04
1.4
1.3
141.38
183.46
u/ml
0.66
243
1640
789
6528
1.28
7.92
3.9
3.6
—
—
—
0
0
119
685
1.77
7.77
1.6
1.3
14.23
12.17
u/l
0.66
97
557
122
710
1.75
7.68
1.4
1.2
10.42
6.86
u/ml
0.20
19
83
2598
24818
1.39
7.66
5.2
4.6
2.86
2.84
mmol/l
0.54
2436
23101
123
719
1.74
7.62
1.4
1.3
5.80
6.88
u/ml
0.14
23
138
439
3362
1.36
7.62
2.0
2.1
29.65
29.39
s
0.38
425
3251
384
2885
1.38
7.51
1.6
1.4
—
—
—
0
0
1333
11777
1.24
7.51
2.6
2.5
—
—
—
0
0
2563
24451
1.37
7.44
4.7
4.1
4.78
4.80
mmol/l
0.38
2413
22888
2550
24308
1.36
7.44
4.6
4.1
1.51
1.53
mmol/l
1.89
2385
22646
263
1852
1.46
7.41
4.1
3.6
1.99
1.91
mmol/l
0.15
233
1559
265
1869
1.46
7.40
4.1
3.6
5.85
5.83
kpa
0.10
259
1817
2462
23383
1.32
7.09
4.1
3.7
1.26
1.26
mmol/l
0.09
2292
21643
371
2800
1.37
7.05
1.8
1.7
—
—
—
0
0
724
6001
1.27
7.04
4.0
3.7
95.17
94.35
%
0.39
705
5825
1824
16738
1.23
6.95
3.3
3.0
41.10
42.80
u/l
0.49
1722
15692
62
299
2.10
6.89
1.6
1.5
—
—
—
0
0
793
6661
1.26
6.87
4.0
3.8
8.54
8.59
mg/mmol
0.01
503
4039
312
2300
1.40
6.83
2.2
2.3
44.11
39.52
u/l
0.16
264
1962
280
2029
1.42
6.76
8.1
7.9
95.81
95.98
%
0.16
269
1968
756
6325
1.26
6.76
3.5
3.2
293.88
316.16
mg/l
0.05
468
3820
265
1904
1.43
6.71
8.4
8.3
123.04
120.59
g/l
1.32
257
1858
188
1265
1.52
6.64
7.3
7.4
24.75
24.56
mmol/l
0.38
179
1206
123
749
1.67
6.61
2.1
2.4
9.72
10.21
g/l
0.69
106
673
37
145
2.57
6.61
1.3
1.5
4.57
5.67
u/l
1.39
28
124
801
6762
1.25
6.60
3.4
3.2
—
—
—
0
0
145
923
1.60
6.54
2.5
2.0
9.36
10.84
nmol/l
1.24
132
820
149
957
1.59
6.48
3.3
2.6
1.30
1.21
%
0.46
149
950
634
5231
1.27
6.32
1.6
1.5
21.05
21.18
nmol/l
0.07
548
4478
33
125
2.66
6.31
3.5
2.5
721.70
915.72
u/ml
0.62
33
125
496
3973
1.30
6.24
1.7
1.7
1216.50
1200.83
nmol/l
0.14
387
3013
260
1887
1.41
6.23
3.2
3.5
1.23
1.23
mmol/l
0.21
213
1639
454
3594
1.31
6.23
2.8
2.7
3.57
3.57
e6/l
0.00
256
1888
359
2757
1.34
6.09
2.6
2.7
5.10
7.12
umol/l
4.28
293
2363
129
815
1.61
6.03
2.2
2.3
3.59
3.59
g/l
0.02
112
746
1199
10640
1.21
6.02
2.1
2.0
—
—
—
0
0
156
1033
1.54
5.96
1.3
1.2
—
—
—
0
0
2287
21658
1.25
5.82
21.3
16.2
331.75
331.77
g/l
0.04
2277
21496
190
1321
1.47
5.75
4.8
5.4
—
—
—
0
0
117
731
1.63
5.74
1.5
1.3
—
—
—
0
0
122
771
1.61
5.71
1.1
1.1
0.79
4.47
u/ml
2.34
15
97
162
1094
1.51
5.66
1.8
1.6
330.96
299.06
mu/l
0.54
137
985
65
344
1.91
5.65
1.3
1.3
42.86
45.90
u/ml
—
7
24
241
1758
1.40
5.63
1.3
1.3
—
—
—
0
0
177
1219
1.48
5.63
2.4
2.3
—
—
—
0
0
61
318
1.94
5.54
1.6
1.3
—
—
—
0
0
67
361
1.88
5.52
1.4
1.4
—
—
—
0
0
236
1722
1.40
5.51
2.5
2.2
6.88
6.53
ug/l
0.07
206
1504
101
615
1.67
5.49
2.7
3.5
511.67
151.56
mg/l
0.34
85
508
101
615
1.67
5.49
2.7
3.5
76.60
39.90
mg/l
0.31
85
508
368
2882
1.32
5.45
1.5
1.4
—
—
—
0
0
258
1915
1.38
5.44
3.8
3.5
—
—
—
0
0
134
882
1.54
5.29
1.7
1.8
1.53
1.52
g/l
0.06
112
769
161
1103
1.49
5.27
2.7
2.7
0.13
0.30
e6/l
2.35
150
1067
36
156
2.32
5.26
1.2
1.2
—
—
—
0
0
303
2322
1.34
5.21
7.8
7.4
1.39
1.13
mmol/l
0.62
247
1834
140
934
1.52
5.21
3.3
2.6
0.63
0.65
%
0.27
140
929
301
2306
1.34
5.19
2.3
2.6
1.68
1.81
%
1.72
267
2058
898
7843
1.21
5.12
2.5
2.2
—
—
—
0
0
123
801
1.56
5.11
12.1
8.8
—
—
—
0
0
223
1636
1.39
5.06
1.4
1.3
29.33
29.01
iu/l
0.04
184
1410
28
113
2.49
4.79
1.4
1.1
—
—
—
0
0
21
73
2.89
4.76
1.1
1.1
—
—
—
0
0
12
21
5.73
4.75
1.1
1.0
—
—
—
0
0
70
403
1.75
4.71
1.3
1.2
—
—
—
0
0
300
2332
1.32
4.69
8.0
7.3
12.63
12.76
kpa
0.13
288
2234
80
479
1.69
4.68
1.6
1.4
30.85
27.95
u/l
0.29
65
400
300
2333
1.32
4.68
8.0
7.3
5.02
5.09
kpa
0.69
288
2235
264
2016
1.34
4.67
4.0
4.2
1.02
0.91
%
0.22
95
625
245
1851
1.35
4.65
3.9
4.0
0.67
0.67
%
0.00
86
543
105
676
1.57
4.61
1.3
1.2
1544.00
926.52
titre
—
5
23
684
5873
1.21
4.58
2.5
2.1
—
—
—
0
0
43
213
2.03
4.57
1.2
1.1
—
—
—
0
0
95
602
1.60
4.47
2.8
3.4
1.16
1.60
ratio
—
8
53
70
412
1.72
4.38
1.5
1.6
—
—
—
0
0
151
1062
1.44
4.37
9.7
10.5
—
—
—
0
0
176
1276
1.40
4.31
10.0
8.6
93.95
94.08
%
0.10
176
1270
79
486
1.64
4.21
2.6
2.3
56.53
101.36
ug/min
1.07
58
298
750
6542
1.20
4.21
1.7
1.6
1.37
1.37
mmol/l
0.02
614
5576
133
922
1.46
4.17
2.2
2.1
21.32
21.25
s
0.04
123
788
99
647
1.55
4.11
2.2
2.3
38.98
37.95
g/l
0.94
84
574
105
700
1.52
4.00
2.1
2.3
307.59
692.07
ug/l
0.64
92
646
216
1641
1.34
3.98
2.6
2.9
—
—
—
0
0
82
518
1.60
3.95
1.0
1.1
3.33
4.87
u/ml
0.69
37
273
74
456
1.64
3.94
2.8
3.7
—
—
—
0
0
144
1026
1.42
3.92
1.1
1.1
—
—
—
0
0
221
1690
1.33
3.90
9.2
8.0
—
—
—
0
0
11
23
4.80
3.87
1.1
1.0
—
—
—
0
0
237
1838
1.31
3.80
4.1
4.3
0.07
0.44
%
0.77
70
446
33
160
2.07
3.76
1.5
1.2
—
—
—
0
0
247
1931
1.30
3.74
4.1
4.3
0.05
0.12
%
1.57
77
539
101
679
1.50
3.72
1.2
1.2
201.11
81.63
titre
—
9
49
119
827
1.46
3.72
4.4
6.2
0.95
0.91
%
0.57
109
779
182
1363
1.36
3.70
2.8
2.1
4161.22
5077.87
u/l
0.18
79
555
66
402
1.66
3.70
1.3
1.3
5.27
4.79
u/ml
0.09
26
165
78
496
1.59
3.68
1.0
1.1
0.37
0.98
u/ml
1.26
34
210
24
103
2.34
3.66
1.7
1.5
—
—
—
0
0
22
92
2.40
3.56
1.1
1.1
20.00
315.79
ng/l
—
5
19
118
827
1.44
3.54
5.0
4.5
—
—
—
0
0
83
542
1.55
3.51
1.2
1.2
—
—
—
0
0
68
426
1.61
3.44
2.1
2.2
5.16
5.45
umol/l
0.11
51
310
79
513
1.55
3.43
1.4
1.4
0.37
0.41
nmol/l
0.22
62
408
217
1690
1.31
3.40
1.4
1.4
—
—
—
0
0
99
679
1.47
3.34
1.2
1.2
—
—
—
0
0
37
196
1.90
3.34
2.9
3.1
49.84
55.13
%
0.73
32
169
231
1825
1.29
3.26
7.8
6.5
1.21
1.32
mmol/l
1.48
226
1780
71
456
1.57
3.25
5.4
9.1
11.42
11.08
mmol/l
0.42
62
414
71
457
1.57
3.23
5.4
9.1
104.34
105.13
mmol/l
0.64
62
415
74
481
1.55
3.22
1.1
1.1
2.66
1.41
u/ml
0.44
33
236
51
302
1.70
3.21
1.2
1.3
—
—
nmol/l
—
0
0
216
1696
1.30
3.20
2.3
2.6
67.78
71.93
e9/l
0.98
159
1271
41
228
1.81
3.20
1.1
1.1
—
—
—
0
0
268
2166
1.26
3.15
2.1
2.3
0.22
0.22
g/l
0.56
259
2038
16
61
2.63
3.13
1.8
2.1
256.00
160.00
e6/l
—
10
37
40
223
1.80
3.10
1.1
1.1
—
—
—
0
0
57
352
1.63
3.08
1.2
1.2
—
0.48
nmol/l
—
0
17
329
2729
1.23
3.07
1.3
1.3
—
—
—
0
0
97
675
1.45
3.07
5.2
7.3
1.30
1.24
mmol/l
0.32
89
591
107
759
1.43
3.06
1.9
2.0
1.24
2.07
ug/l
0.88
92
672
259
2100
1.26
2.98
4.1
3.7
—
—
—
0
0
191
1492
1.30
2.96
1.3
1.2
—
—
—
0
0
67
435
1.55
2.96
1.1
1.1
—
—
—
0
0
67
435
1.55
2.96
1.1
1.1
—
—
—
0
0
67
439
1.54
2.85
3.2
2.2
—
—
—
0
0
96
678
1.43
2.83
2.4
2.5
—
—
—
0
0
114
831
1.39
2.81
4.3
6.1
1.71
1.58
%
0.48
104
783
71
473
1.51
2.81
1.5
1.3
—
—
—
0
0
155
1186
1.32
2.80
3.0
3.3
—
—
—
0
0
69
458
1.52
2.78
1.9
2.6
—
—
—
0
0
89
623
1.44
2.76
1.5
1.3
717.54
508.44
mg/l
0.37
82
594
138
1041
1.34
2.76
1.7
1.6
—
—
—
0
0
37
210
1.77
2.74
1.2
1.1
—
—
—
0
0
43
255
1.70
2.74
2.4
1.8
154.62
185.05
pmol/l
1.01
37
237
84
585
1.45
2.69
1.1
1.1
1.87
2.13
u/ml
0.08
37
306
279
2309
1.23
2.69
5.0
4.0
—
—
—
0
0
22
105
2.10
2.68
1.2
1.1
184.00
216.55
iu/ml
0.22
22
105
378
3226
1.20
2.66
1.3
1.2
—
—
—
0
0
153
1179
1.31
2.65
1.8
1.9
—
—
—
0
0
79
551
1.45
2.53
1.5
1.3
3.64
3.69
mmol/l
0.14
73
524
19
88
2.17
2.50
1.3
1.1
—
3.80
—
0
5
30
165
1.83
2.49
1.2
1.4
2060.57
1920.17
ml
0.43
30
160
63
422
1.50
2.47
1.1
1.0
—
—
—
0
0
71
489
1.46
2.43
1.3
1.4
—
—
—
0
0
77
539
1.44
2.43
4.0
4.2
—
—
—
0
0
65
441
1.48
2.41
3.1
2.8
—
—
—
0
0
50
321
1.57
2.38
1.3
1.2
—
—
—
0
0
35
205
1.72
2.37
1.1
1.2
0.07
1.26
u/ml
1.75
21
103
378
3264
1.18
2.34
2.2
2.0
—
—
—
0
0
19
91
2.09
2.32
2.9
2.2
—
—
—
0
0
106
791
1.35
2.32
2.9
3.2
0.42
0.27
g/l
0.53
45
299
51
333
1.54
2.27
2.6
3.3
1.11
1.38
%
0.51
46
296
35
208
1.69
2.26
1.6
1.4
45.63
35.08
%
0.76
24
120
69
481
1.44
2.25
2.0
2.0
4.80
5.13
mmol/24h
0.35
61
420
32
186
1.73
2.24
1.7
1.5
10.55
11.27
umol/l
0.28
32
175
29
164
1.78
2.23
2.3
2.3
10.81
10.87
%
0.03
29
164
14
60
2.34
2.21
1.3
1.1
—
—
—
0
0
14
60
2.34
2.21
1.3
1.1
—
—
—
0
0
14
60
2.34
2.21
1.3
1.1
—
—
—
0
0
56
376
1.50
2.20
1.2
1.4
62.62
61.99
mmol/l
0.04
47
309
25
136
1.85
2.17
2.4
2.7
42.79
45.02
%
0.22
19
78
64
444
1.45
2.15
1.4
1.4
129.12
113.70
u/ml
0.20
13
82
22
115
1.92
2.15
2.5
1.5
14.27
12.85
u/l
0.33
22
110
60
411
1.47
2.15
1.1
1.0
1.39
2.76
u/ml
1.60
24
195
76
545
1.40
2.14
1.4
1.4
53.44
25.11
e6/l
0.31
63
424
40
251
1.60
2.12
1.6
1.4
—
—
—
0
0
76
546
1.40
2.12
1.5
1.4
2207.02
1517.12
e6/l
0.13
66
449
34
205
1.67
2.11
1.1
1.1
404.29
393.12
nmol/l
0.13
28
182
9
31
2.91
2.07
1.0
1.1
—
—
—
0
0
71
507
1.41
2.06
1.6
1.4
—
—
—
0
0
6
15
4.01
2.04
1.0
1.1
—
—
—
0
0
89
663
1.35
2.01
2.5
2.4
—
—
—
0
0
14
63
2.23
2.00
1.1
1.4
34.89
46.93
%
—
9
53
47
311
1.52
2.00
2.7
2.6
—
—
—
0
0
68
485
1.41
1.99
1.2
1.2
322.60
263.89
u/ml
0.42
50
293
36
224
1.61
1.99
2.9
3.9
—
—
—
0
0
126
991
1.28
1.95
1.4
1.3
214.93
223.37
miu/ml
0.10
65
513
30
179
1.68
1.95
1.1
1.2
115.00
216.76
titre
—
6
34
55
379
1.46
1.94
1.0
1.1
17.68
4.46
u/ml
0.40
16
151
211
1761
1.21
1.94
2.8
2.6
4.05
5.15
e9/l
1.70
170
1464
16
78
2.06
1.90
1.8
1.3
130.59
144.45
pmol/l
0.19
16
78
7
22
3.19
1.88
2.0
1.4
58.43
42.05
umol/l
—
7
22
73
536
1.37
1.83
1.8
1.7
8056.86
10949.79
e6/l
0.55
50
384
5
12
4.17
1.82
1.2
1.0
—
—
—
0
0
5
12
4.17
1.82
1.2
1.0
—
—
—
0
0
70
513
1.37
1.78
4.1
3.5
17.38
24.60
mg/l
1.57
40
319
21
116
1.82
1.78
3.2
3.4
—
—
—
0
0
9
36
2.50
1.74
1.1
1.1
—
—
—
0
0
33
209
1.59
1.73
1.3
1.4
67065.70
99096.35
e6/l
0.18
23
139
284
2465
1.17
1.70
1.5
1.4
—
—
—
0
0
11
48
2.30
1.70
1.5
1.1
—
—
—
0
0
26
157
1.66
1.65
1.0
1.0
—
—
—
0
0
32
204
1.57
1.65
1.4
1.2
33.27
35.10
mg/l
0.14
27
173
7
25
2.80
1.65
4.1
1.7
—
—
—
0
0
63
461
1.37
1.64
2.1
2.3
131.22
128.52
g/l
0.45
36
339
52
368
1.42
1.64
2.8
3.1
0.86
0.79
nmol/l
0.36
42
293
28
174
1.62
1.60
1.0
1.1
0.06
3.09
u/ml
—
7
60
50
353
1.42
1.60
1.1
1.2
—
—
—
0
0
121
975
1.25
1.59
2.4
1.8
—
—
—
0
0
14
70
2.00
1.59
1.1
1.4
—
—
—
0
0
7
26
2.70
1.58
1.4
1.0
—
—
—
0
0
36
239
1.51
1.57
3.3
2.3
—
—
—
0
0
351
3116
1.14
1.56
1.6
1.6
—
—
—
0
0
20
114
1.76
1.56
1.5
2.8
113.50
194.11
umol/l
—
8
62
17
92
1.85
1.56
1.1
1.4
52.76
82.98
nmol/24h
1.26
17
92
57
415
1.38
1.55
1.2
1.1
—
—
—
0
0
5
15
3.34
1.52
2.4
5.2
18.80
18.25
mg/l
—
5
15
57
417
1.37
1.51
1.1
1.1
6.77
3.79
u/ml
0.35
19
194
30
193
1.56
1.51
1.2
1.4
—
—
—
0
0
121
983
1.24
1.50
2.4
1.8
—
—
—
0
0
151
1258
1.21
1.47
7.3
6.7
24.94
24.91
mmol/l
0.04
151
1252
61
454
1.35
1.46
1.3
1.2
—
—
—
0
0
119
968
1.24
1.46
2.4
1.8
—
—
—
0
0
969
9130
1.09
1.45
2.9
2.6
—
—
—
0
0
120
979
1.24
1.44
2.4
1.8
—
—
—
0
0
5
16
3.13
1.44
1.2
1.5
—
—
—
0
0
89
702
1.28
1.42
1.3
1.4
300.69
299.60
ug/g
0.02
49
379
155
1301
1.20
1.41
3.2
3.5
5.26
5.15
kpa
1.00
148
1238
27
173
1.57
1.40
1.0
1.0
—
—
—
0
0
7
29
2.42
1.39
1.0
1.1
—
—
—
0
0
25
158
1.59
1.37
1.7
1.5
—
—
—
0
0
26
166
1.57
1.37
1.0
1.1
—
—
—
0
0
115
944
1.23
1.32
3.2
3.5
—
—
—
0
0
15
83
1.81
1.31
1.7
1.8
—
—
—
0
0
152
1286
1.19
1.29
3.3
3.4
7.41
7.41
ph
0.08
15
155
110
902
1.23
1.28
2.5
1.9
—
—
—
0
0
16
92
1.74
1.25
1.2
1.3
—
0.28
g/l
—
0
10
19
115
1.66
1.24
1.3
1.2
—
—
—
0
0
5
19
2.63
1.21
1.0
1.2
—
—
—
0
0
203
1775
1.15
1.17
2.6
3.3
56.20
51.60
u/ml
0.09
195
1708
86
695
1.24
1.17
2.3
3.0
—
—
—
0
0
8
39
2.05
1.15
1.3
1.4
—
—
—
0
0
5
20
2.50
1.15
1.2
1.1
—
—
—
0
0
15
87
1.73
1.15
1.7
2.2
2.07
1.02
ug/l
0.74
15
80
16
95
1.69
1.13
2.4
1.7
—
—
—
0
0
30
208
1.45
1.12
1.1
1.2
—
—
—
0
0
17
103
1.65
1.12
3.5
2.8
—
—
—
0
0
7
136
0.51
1.09
2.0
2.7
44471.43
39040.33
ug/l
—
7
136
21
136
1.55
1.08
1.3
1.2
—
—
—
0
0
100
830
1.21
1.08
3.1
3.6
25.15
24.89
mmol/l
0.42
94
766
343
3125
1.11
1.05
1.8
1.8
—
—
—
0
0
58
454
1.28
1.05
1.5
1.4
4.10
3.79
ug/l
0.05
53
409
15
90
1.67
1.04
1.1
1.3
—
—
—
0
0
9
46
1.96
1.03
1.2
1.2
0.05
0.05
u/ml
—
9
46
75
609
1.24
1.01
1.1
1.1
—
—
—
0
0
5
106
0.47
1.01
1.2
2.4
—
—
—
0
0
53
413
1.29
1.00
1.8
1.6
—
—
—
0
0
241
2164
1.12
0.97
1.4
1.4
—
—
—
0
0
10
54
1.85
0.96
1.3
1.3
21.32
54.99
mu/l
—
5
44
45
346
1.31
0.95
1.0
1.0
0.03
0.20
u/ml
1.70
11
99
51
399
1.28
0.95
1.2
1.1
290.43
1444.33
iu/ml
0.41
14
93
14
85
1.65
0.94
2.4
3.6
8.46
7.55
mg/l
0.20
14
70
91
761
1.20
0.94
1.2
1.2
—
—
—
0
0
7
37
1.89
0.94
1.1
1.8
—
—
—
0
0
35
261
1.35
0.91
1.5
2.2
—
—
—
0
0
28
201
1.40
0.91
1.2
2.0
—
—
—
0
0
12
71
1.69
0.88
1.2
1.2
—
—
—
0
0
10
56
1.79
0.87
1.1
1.1
0.50
0.69
umol/24h
—
5
35
59
478
1.24
0.85
2.2
3.9
8.96
8.69
kpa
0.53
59
473
346
3204
1.09
0.80
5.4
4.7
2.77
2.42
ug/l
0.17
315
2861
28
207
1.36
0.79
1.4
1.4
2556.37
2627.83
e6/l
0.03
19
144
37
286
1.30
0.78
2.1
1.5
57.86
57.04
%
0.04
28
174
13
82
1.59
0.78
1.2
2.1
6.52
10.14
mg/l
2.79
13
66
70
584
1.20
0.78
2.3
3.8
7.42
7.42
ph
0.29
60
528
40
313
1.28
0.78
1.1
1.1
1.58
1.51
g/l
0.42
35
278
18
123
1.47
0.77
1.1
1.1
2198.51
1500.51
miu/ml
1.33
18
123
0
28
0.00
0.76
0.0
1.3
—
139.42
—
0
6
25
183
1.37
0.75
1.4
1.4
58949.62
85501.46
e6/l
0.21
13
100
90
771
1.17
0.75
2.7
1.8
—
—
—
0
0
253
2317
1.10
0.75
3.2
4.0
14.71
24.43
ug/l
0.49
195
1828
58
477
1.22
0.75
2.2
3.9
1.92
2.65
mmol/l
1.47
36
325
5
24
2.09
0.74
1.8
1.2
—
—
—
0
0
5
24
2.09
0.74
9.2
9.5
5.68
5.82
mmol/l
—
5
24
58
478
1.22
0.74
2.2
3.9
4.93
5.07
kpa
0.90
58
473
57
469
1.22
0.73
1.6
1.7
—
—
—
0
0
14
92
1.52
0.72
1.1
1.3
—
—
—
0
0
31
238
1.31
0.70
1.3
1.2
—
—
—
0
0
5
27
1.85
0.68
2.6
2.1
93.56
57.39
pmol/l
—
5
21
12
77
1.56
0.68
1.2
1.2
20.33
8.70
%
—
6
10
242
2629
0.91
0.68
1.3
1.3
—
—
—
0
0
7
42
1.67
0.68
1.1
1.0
—
—
—
0
0
7
42
1.67
0.68
1.1
1.0
—
—
—
0
0
7
42
1.67
0.68
1.1
1.0
—
—
—
0
0
7
43
1.63
0.66
2.3
1.3
—
—
—
0
0
80
689
1.17
0.65
6.1
2.5
—
—
—
0
0
7
44
1.59
0.65
1.3
1.9
—
—
—
0
0
24
181
1.33
0.63
1.8
2.2
1.89
2.23
u/field
—
9
81
44
360
1.23
0.62
1.3
1.5
—
—
—
0
0
10
63
1.59
0.61
1.1
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
89
779
1.15
0.60
2.7
3.5
263.97
2018.96
u/ml
0.74
72
662
11
163
0.67
0.60
1.1
1.1
—
—
—
0
0
23
175
1.32
0.58
1.3
1.5
—
—
—
0
0
24
184
1.31
0.57
1.3
1.7
5.06
3.69
mg/l
0.33
24
178
19
253
0.75
0.57
1.2
1.3
—
—
—
0
0
22
167
1.32
0.56
2.2
2.6
649.27
687.68
e6/l
0.15
22
161
28
223
1.26
0.52
3.7
6.8
7.14
6.99
mmol/l
0.09
18
181
6
97
0.62
0.52
1.5
2.6
—
—
—
0
0
6
40
1.50
0.51
1.2
1.1
—
—
—
0
0
9
64
1.41
0.51
3.6
4.7
—
—
—
0
0
16
118
1.36
0.50
2.1
1.3
1.86
4.55
%
—
7
20
34
280
1.22
0.48
1.2
1.2
—
—
—
0
0
21
163
1.29
0.48
1.5
1.4
74.81
76.17
umol/l
0.12
21
163
13
93
1.40
0.48
2.1
3.0
—
—
—
0
0
17
128
1.33
0.47
1.6
1.6
2.33
3.34
u/field
—
9
93
11
77
1.43
0.45
1.3
1.1
—
—
—
0
0
30
246
1.22
0.45
1.3
1.6
281.75
278.46
mosm/kgh2o
0.42
24
193
19
147
1.29
0.45
2.2
3.2
—
—
—
0
0
15
112
1.34
0.44
1.1
1.4
183.53
154.41
mmol/24h
0.52
15
112
32
265
1.21
0.44
3.1
2.7
—
—
—
0
0
24
193
1.25
0.43
1.7
1.6
6.07
6.60
mmol/l
0.51
15
136
11
78
1.41
0.43
1.0
1.0
—
—
—
0
0
6
91
0.66
0.42
1.7
1.1
—
—
—
0
0
752
7299
1.04
0.42
1.6
1.5
—
—
—
0
0
22
176
1.25
0.41
2.8
2.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
61.20
—
0
10
44
379
1.16
0.41
1.4
1.4
6.24
7.13
mmol/l
1.64
36
336
200
1877
1.07
0.40
3.3
2.9
0.67
0.75
ug/l
1.21
138
1190
113
1038
1.09
0.39
1.1
1.1
—
—
—
0
0
12
89
1.35
0.38
2.9
3.2
—
—
—
0
0
22
180
1.22
0.36
1.2
1.1
1.08
1.04
ratio
—
8
69
49
432
1.14
0.35
2.5
2.4
15.78
16.26
%
0.32
16
210
20
163
1.23
0.34
1.4
1.4
—
—
—
0
0
14
109
1.29
0.33
1.3
1.5
—
—
—
0
0
17
210
0.81
0.33
1.5
1.5
0.93
0.96
g/l
0.16
17
210
28
328
0.85
0.32
1.1
1.2
—
—
—
0
0
49
436
1.13
0.32
1.6
1.5
—
—
—
0
0
35
304
1.15
0.31
2.5
2.5
—
—
—
0
0
7
56
1.25
0.29
1.4
1.9
—
—
—
0
0
11
141
0.78
0.29
1.2
1.3
—
—
—
0
0
18
148
1.22
0.29
1.3
1.1
—
—
—
0
0
20
238
0.84
0.28
1.6
1.4
7.45
8.12
mmol/l
0.29
20
230
10
76
1.32
0.28
1.1
1.4
—
—
—
0
0
124
1168
1.06
0.26
1.4
1.4
—
—
—
0
0
11
86
1.28
0.26
1.1
1.1
11.51
1.87
u/ml
—
5
46
5
71
0.70
0.26
1.4
2.1
—
—
—
0
0
9
72
1.25
0.25
1.2
1.5
—
—
—
0
0
11
88
1.25
0.22
1.0
1.1
—
—
—
0
0
10
79
1.27
0.22
1.0
1.2
—
—
—
0
0
13
107
1.22
0.21
1.5
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
63
585
1.08
0.21
2.2
3.7
1.35
1.47
mg/l
0.85
57
548
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
6
49
1.22
0.20
1.0
1.0
—
—
—
0
0
24
271
0.88
0.20
1.1
1.0
—
—
—
0
0
28
250
1.12
0.19
1.7
1.5
—
—
—
0
0
6
51
1.18
0.19
2.2
1.7
—
—
—
0
0
15
174
0.86
0.17
1.3
1.2
—
—
—
0
0
20
176
1.14
0.17
1.8
1.5
0.91
1.20
promille
0.41
13
136
21
186
1.13
0.17
1.2
1.2
—
—
—
0
0
21
187
1.12
0.15
1.0
1.1
—
—
—
0
0
9
81
1.11
0.15
1.9
1.5
—
—
—
0
0
37
342
1.08
0.15
1.8
1.6
—
—
—
0
0
23
208
1.11
0.14
2.9
3.2
10.69
34.15
mg/l
1.77
17
145
8
100
0.80
0.13
1.1
1.6
—
—
—
0
0
15
132
1.14
0.13
1.3
1.5
164.40
131.75
nmol/l
0.95
15
132
169
1644
1.03
0.12
1.4
1.4
—
—
—
0
0
37
346
1.07
0.12
3.8
2.7
—
—
—
0
0
46
487
0.94
0.12
3.5
3.6
56.54
56.94
%
0.09
46
487
23
249
0.92
0.10
2.1
3.0
—
—
—
0
0
5
46
1.09
0.09
4.6
6.5
—
—
—
0
0
16
176
0.91
0.09
1.5
1.3
1.50
1.61
g/l
0.81
16
176
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
25
234
1.07
0.08
1.7
2.5
1.51
1.17
g/24h
0.17
16
113
7
66
1.06
0.08
1.0
1.1
—
—
—
0
0
7
67
1.04
0.08
1.0
1.0
—
—
—
0
0
6
74
0.81
0.07
1.3
1.7
—
—
—
0
0
20
186
1.08
0.07
1.5
1.6
—
—
—
0
0
293
2893
1.01
0.07
4.6
4.3
33.35
32.81
%
0.38
225
1989
10
89
1.12
0.06
8.5
9.9
—
—
—
0
0
50
482
1.04
0.06
1.5
2.3
0.73
0.83
nmol/l
0.71
43
397
19
203
0.94
0.06
1.4
1.2
—
—
—
0
0
77
786
0.98
0.04
1.5
1.4
—
—
—
0
0
79
806
0.98
0.04
1.5
1.5
—
—
—
0
0
35
338
1.04
0.04
4.8
5.3
350.10
367.32
umol/l
0.32
29
291
77
783
0.98
0.03
1.5
1.4
—
—
—
0
0
11
102
1.08
0.03
2.0
1.9
—
—
—
0
0
77
759
1.01
0.02
1.2
1.3
—
—
—
0
0
24
248
0.97
0.02
2.6
2.8
—
—
—
0
0
10
93
1.08
0.02
1.0
1.2
—
—
—
0
0
30
292
1.03
0.02
1.4
1.6
—
1506.67
—
0
6
17
171
0.99
0.00
1.4
1.2
—
—
—
0
0
44
442
1.00
0.00
2.9
3.5
—
—
—
0
0
13
133
0.98
0.00
1.0
1.0
1001.88
725.46
ng/l
—
8
85
0
9
0.00
0.00
0.0
3.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
8
86
0.93
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
25.80
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
59
0.85
-0.00
1.6
1.4
35.40
31.78
%
—
5
37
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
21
210
1.00
-0.00
1.3
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
79.14
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
36.3
31.2
7.26
7.44
ug/l
—
9
82
0
5
0.00
-0.00
0.0
1.0
—
281.26
—
0
5
6
62
0.97
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint THYROIDITIS and mortality.

Females

Parameter HR [95% CI] p-value
THYROIDITIS 1.008 [0.89, 1.14] 0.906
Birth year 0.996 [0.99, 1.01] 0.422

During the follow-up period (1.1.1998 — 31.12.2019), 612 out of 10163 females with THYROIDITIS died.

Males

Parameter HR [95% CI] p-value
THYROIDITIS 0.815 [0.7, 0.94] 0.007
Birth year 0.99 [0.98, 1.0] 0.034

During the follow-up period (1.1.1998 — 31.12.2019), 242 out of 2542 males with THYROIDITIS died.

Mortality risk

Mortality risk for people of age

years, who have THYROIDITIS.

N-year risk Females Males
1 0.087% 0.169%
5 0.579% 1.044%
10 1.518% 2.768%
15 2.872% 5.227%
20 5.1% 8.575%

Relationships between endpoints

Index endpoint: THYROIDITIS – Thyroiditis

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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