subacute thyroiditis: Spontaneously remitting inflammatory condition of the THYROID GLAND, characterized by FEVER; MUSCLE WEAKNESS; SORE THROAT; severe thyroid PAIN; and an enlarged damaged gland containing GIANT CELLS. The disease frequently follows a viral infection.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1451 |
4. Check minimum number of eventsNone |
1451 |
5. Include endpointsNone |
1451 |
6. Filter based on genotype QC (FinnGen only) |
1396 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF10
- Parent code in ICD-10
- E06
- Name in latin
- Thyreoiditis subacuta
Similar endpoints
↥List of similar endpoints to
Subacute thyroiditis
based on the number of shared cases.
Similar with more cases:
- Thyroiditis
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8817 | 6740 | 2008 |
| Only index persons | 8221 | 6380 | 1841 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.19 | 0.06 |
| Only index persons | 0.20 | 0.23 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 48.24 | 47.71 | 50.24 |
| Only index persons | 47.78 | 47.28 | 49.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1396 | 1152 | 244 |
| Unadjusted period prevalence (%) | 0.36 | 0.41 | 0.11 |
| Median age at first event (years) | 48.34 | 48.00 | 49.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1451
- Matched controls
- 14510
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
114.7
307.7
286
31
H03AA01
ATC
levothyroxine sodium; systemic
49.5
307.7
564
184
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
307.7
1205
*
H03BB01
ATC
carbimazole; oral
129.7
257.6
130
11
E03
ICD-10 Finland
Other hypothyroidism
115.6
229.2
117
11
104
Kela drug reimbursment
Thyroid insufficiency
331.3
148.6
148
5
E03.89
ICD-10 Finland
Other specified hypothyroidism
82.4
146.5
78
10
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
57.9
145.5
82
15
H02AB06
ATC
prednisolone; systemic
4.2
143.4
1000
5041
T86
ICPC
Hypothyroidism/myxoedema
68.6
142.6
78
12
2451A
ICD-9 Finland
Thyroiditis, Subacute thyroiditis
+∞
136.7
129
*
E06.9
ICD-10 Finland
Thyroiditis, unspecified
271.1
100.1
101
*
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
23.4
92.1
67
30
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
167.4
90.3
94
6
24500
ICD-8 Finland
Thyroiditis, Subacuta de Quervain
+∞
77.8
74
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.6
75.8
155
306
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
267.1
75.2
76
*
E06.0
ICD-10 Finland
Acute thyroiditis
+∞
69.3
66
*
H02AB07
ATC
prednisone; oral
3.2
66.1
313
1140
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
623.5
61.2
60
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
17.2
60.2
50
30
BAA60
NOMESCO Finland
Total thyroidectomy
153.6
56.3
59
*
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
22.9
51.9
38
17
C07AA05
ATC
propranolol; systemic
2.5
50.9
411
1958
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
11.7
50.2
52
46
24501
ICD-8 Finland
Thyroiditis, Subacuta alia
+∞
49.2
47
*
R07.0
ICD-10 Finland
Pain in throat
3.7
49.1
172
513
E06
ICD-10 Finland
Thyroiditis
472.4
46.6
46
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
+∞
46.1
44
*
BA1AE, ,
SPAT
10.1
41.1
47
48
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
13.6
38.3
36
27
R50.9
ICD-10 Finland
Fever, unspecified
2.5
36.8
262
1158
R53
ICD-10 Finland
Malaise and fatigue
2.2
35.1
406
2207
E06.3
ICD-10 Finland
Autoimmune thyroiditis
80.2
35.0
39
5
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
12.4
34.2
34
28
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
43.2
34.2
42
10
R21
ICPC
Throat symptom/complaint
2.1
31.5
377
2066
A02BC02
ATC
pantoprazole; systemic
2.0
30.1
1031
8021
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
27.4
587
3891
EP1AE, ,
SPAT
5.0
26.6
58
120
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
26.3
419
2518
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
22.3
25.7
37
17
A02BC05
ATC
esomeprazole; systemic
1.8
24.1
633
4414
E03.82
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
24.0
23
*
R51.80
ICD-10 Finland
Headache
2.1
23.6
278
1497
R52.9
ICD-10 Finland
Pain, unspecified
2.4
22.6
166
737
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
22.4
405
2514
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
60.9
20.9
24
*
A03
ICPC
Fever
2.0
20.3
271
1518
M79.6
ICD-10 Finland
Pain in limb
1.7
20.0
639
4630
T85
ICPC
Hyperthyroidism/thyrotoxicosis
55.8
19.0
22
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
18.5
750
5734
G44.2
ICD-10 Finland
Tension-type headache
2.0
18.1
240
1338
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
17.4
402
2651
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
+∞
16.7
16
*
A02BC03
ATC
lansoprazole; oral
1.7
16.5
420
2834
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.3
16.1
62
195
M54.5
ICD-10 Finland
Low back pain
1.6
15.7
532
3848
R06.0
ICD-10 Finland
Dyspnoea
1.7
15.3
357
2349
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
15.2
182
976
N03AX16
ATC
[U] pregabalin
1.7
14.9
338
2206
A02BC01
ATC
omeprazole; systemic
1.7
14.8
385
2604
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
14.7
399
2725
J02AC01
ATC
fluconazole; systemic
1.6
14.6
658
5058
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
14.3
277
1728
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.0
14.3
161
845
M79.7
ICD-10 Finland
Fibromyalgia
2.9
14.2
69
249
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.9
13.9
193
1087
J01AA02
ATC
doxycycline; systemic
1.6
13.7
1120
9769
N01
ICPC
Headache
1.9
13.6
176
968
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
+∞
13.6
13
*
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
+∞
13.6
13
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
13.4
320
2109
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
13.3
403
2817
K30
ICD-10 Finland
Functional dyspepsia
1.9
13.3
176
977
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
40.5
13.2
16
*
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
28.6
13.0
17
6
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
50.5
12.9
15
*
R42
ICD-10 Finland
Dizziness and giddiness
1.6
12.7
312
2068
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.3
12.7
102
469
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
12.5
186
1071
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
2.5
12.4
79
328
J01DA01
ATC
[U] cefalexin
1.5
12.3
875
7300
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
2.4
12.2
84
361
L02
ICPC
Back symptom/complaint
1.9
12.1
155
849
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
12.1
571
4381
P01AB01
ATC
metronidazole; oral, rectal
1.5
11.9
605
4708
C07AB07
ATC
bisoprolol; oral
1.5
11.8
583
4506
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
11.8
265
1715
R00.2
ICD-10 Finland
Palpitations
2.0
11.7
128
665
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
2.7
11.6
61
230
SPAT1283
SPAT
Restricted health certificate
1.7
11.6
259
1672
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
11.5
11
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.2
11.5
104
503
R13
ICD-10 Finland
Dysphagia
2.2
11.3
96
452
R51
ICD-10 Finland
Headache
2.2
11.2
90
415
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
11.1
359
2533
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
11.0
460
3426
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
11.0
180
1065
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.4
11.0
39
117
J01FA10
ATC
azithromycin; systemic
1.5
11.0
838
7016
M25.5
ICD-10 Finland
Pain in joint
1.5
10.9
470
3523
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
10.8
266
1757
R03AC02
ATC
salbutamol; inhalant
1.5
10.8
785
6502
R01AD08
ATC
fluticasone; nasal
1.5
10.7
415
3041
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
60.4
10.6
12
*
D06
ICPC
Abdominal pain localized other
1.9
10.6
129
695
L17
ICPC
Foot/toe symptom/complaint
1.5
10.5
395
2876
SPAT1301
SPAT
No procedures
1.5
10.4
401
2933
N06AX11
ATC
mirtazapine; oral
1.5
10.4
460
3460
UJF32
NOMESCO Finland
Coloscopy
1.5
10.4
335
2358
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
10.4
336
2367
A04
ICPC
Weakness/tiredness general
1.7
10.3
192
1178
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.9
10.2
126
681
R01AD09
ATC
mometasone; nasal
1.4
10.2
655
5282
M03BX02
ATC
tizanidine; oral
1.4
10.1
899
7688
R06AX27
ATC
desloratadine; oral
1.5
10.0
423
3149
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
9.9
79
363
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
9.9
61
250
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
9.7
112
593
G43.9
ICD-10 Finland
Migraine, unspecified
2.1
9.7
97
488
N02BE01
ATC
paracetamol; systemic, rectal
1.7
9.6
1263
11628
R01AD58
ATC
fluticasone, combinations; nasal
1.5
9.5
354
2561
M79.1
ICD-10 Finland
Myalgia
1.6
9.5
212
1364
R03DC03
ATC
montelukast; oral
1.6
9.5
243
1619
R74
ICPC
Upper respiratory infection acute
1.5
9.5
462
3529
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
9.4
228
1499
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
+∞
9.4
9
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.3
239
1591
A02BC04
ATC
rabeprazole; oral
1.8
9.2
137
787
J01FA06
ATC
roxithromycin; oral
1.4
9.2
550
4356
M54
ICD-10 Finland
Dorsalgia
1.7
9.2
172
1057
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
9.2
261
1781
N02AX02
ATC
tramadol; systemic, rectal
1.4
9.2
546
4320
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
9.1
104
548
L03
ICPC
Low back symptom/complaint
1.5
9.0
384
2852
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.9
371
2741
M54.3
ICD-10 Finland
Sciatica
2.1
8.9
89
447
L01
ICPC
Neck symptom/complaint
1.6
8.9
231
1542
N03AX12
ATC
[U] gabapentin; oral
1.6
8.8
225
1497
J35.0
ICD-10 Finland
Chronic tonsillitis
2.1
8.7
79
382
R39.1
ICD-10 Finland
Other difficulties with micturition
3.1
8.7
35
114
Z01.2
ICD-10 Finland
Dental examination
1.4
8.7
627
5115
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
8.7
177
1113
H02AB04
ATC
methylprednisolone; systemic
1.6
8.6
192
1234
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
8.6
211
1389
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
8.6
200
1300
R83
ICPC
Respiratory infection other
1.5
8.4
361
2679
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
8.3
170
1068
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
+∞
8.3
8
*
E06.5
ICD-10 Finland
Other chronic thyroiditis
+∞
8.3
8
*
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.3
426
3270
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
8.3
309
2232
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
8.2
113
634
D01
ICPC
Abdominal pain/cramps general
1.7
8.2
164
1025
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.2
1008
8952
J01MA02
ATC
ciprofloxacin; systemic
1.4
8.1
473
3708
C07AB02
ATC
metoprolol; systemic
1.6
8.1
223
1508
J45
ICD-10 Finland
Asthma
1.7
8.0
148
905
R12
ICD-10 Finland
Heartburn
1.8
7.9
115
656
N17
ICPC
Vertigo/dizziness
1.7
7.9
158
987
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
7.8
128
757
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.8
7.8
107
600
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
7.8
575
4686
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
7.7
141
860
J01FA09
ATC
clarithromycin; systemic
1.4
7.7
427
3314
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.8
7.7
121
708
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
7.6
98
538
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.2
7.6
62
288
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
7.6
242
1688
N05CF01
ATC
zopiclone; oral
1.4
7.6
408
3151
R01AD12
ATC
fluticasone furoate; nasal
1.4
7.5
439
3434
D11
ICPC
Diarrhoea
1.6
7.5
161
1026
R05
ICD-10 Finland
Cough
1.5
7.4
281
2030
SPAT1263
SPAT
Sampling
1.4
7.4
541
4390
SFA20
NOMESCO Finland
Two-surface restoration
1.4
7.4
812
7020
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
7.4
191
1273
R49.01
ICD-10 Finland
Functional dysphonia
2.4
7.4
50
215
J01DB01
ATC
cefalexin; oral
1.4
7.4
1146
10482
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
7.3
7
*
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
7.3
92
503
L04
ICPC
Chest symptom/complaint
1.9
7.2
93
511
M54.6
ICD-10 Finland
Pain in thoracic spine
1.8
7.2
108
623
D02
ICPC
Abdominal pain epigastric
1.9
7.1
87
470
M01AH05
ATC
etoricoxib; oral
1.4
7.1
857
7491
N89
ICPC
Migraine
2.3
7.1
54
244
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
7.1
71
358
UJD02
NOMESCO Finland
Gastroscopy
2.1
7.1
62
297
XQ800
NOMESCO Finland
Prick test
1.8
7.1
111
649
R05
ICPC
Cough
1.4
7.1
325
2436
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
7.1
373
2865
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
7.0
43
176
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
7.0
111
650
R02
ICPC
Shortness of breath/dyspnoea
1.6
7.0
155
994
S04
ICPC
Lump/swelling localized
1.7
7.0
133
821
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
7.0
397
3088
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.9
234
1655
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
6.8
135
841
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.8
795
6895
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
6.8
133
828
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
6.7
226
1592
M01AE02
ATC
naproxen; oral, rectal
1.3
6.7
782
6774
N76.0
ICD-10 Finland
Acute vaginitis
1.8
6.7
102
591
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.1
6.7
59
284
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.6
688
5859
M35.7
ICD-10 Finland
Hypermobility syndrome
3.1
6.6
26
84
N06AX26
ATC
vortioxetine; oral
1.8
6.6
91
512
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
4.2
6.6
17
41
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.0
6.6
64
320
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
6.5
90
506
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.5
419
3319
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.5
326
2479
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.4
639
5399
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
6.4
76
407
L50.9
ICD-10 Finland
Urticaria, unspecified
2.2
6.4
52
242
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
6.4
168
1123
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.4
539
4449
N06AX21
ATC
duloxetine; oral
1.6
6.4
156
1026
R07.3
ICD-10 Finland
Other chest pain
1.6
6.3
129
811
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.3
6.3
46
205
R03AC03
ATC
terbutaline; inhalant
1.5
6.3
184
1260
A05
ICPC
Feeling ill
1.9
6.3
78
425
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
6.3
6
*
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
+∞
6.3
6
*
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
6.3
6
*
A01
ICPC
Pain general/multiple sites
1.7
6.2
118
727
E04.8
ICD-10 Finland
Other specified nontoxic goitre
26.8
6.2
8
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.2
535
4423
H57.1
ICD-10 Finland
Ocular pain
2.1
6.2
56
272
M01AB05
ATC
diclofenac; systemic, rectal
1.3
6.2
896
7965
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.2
459
3710
EMAK, ,
NOMESCO Finland
2.2
6.2
51
239
T74.1
ICD-10 Finland
Physical abuse
2.9
6.2
27
93
N64.4
ICD-10 Finland
Mastodynia
2.1
6.1
54
260
A11
ICPC
Chest pain NOS
1.8
6.1
97
570
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
6.1
114
701
EMB10
NOMESCO Finland
Tonsillectomy
1.9
6.1
73
393
R06AE07
ATC
cetirizine; oral
1.3
6.1
604
5093
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.1
581
4873
J30.0
ICD-10 Finland
Vasomotor rhinitis
2.5
6.1
35
140
T81
ICPC
Goitre
10.1
6.0
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
222
122
21.30
284.14
1.9
1.1
2.84
1.54
iu/l
3.39
79
21
414
621
8.93
278.61
1.5
1.1
163.17
78.49
iu/ml
2.57
196
192
293
385
9.28
217.31
3.4
1.4
4.63
4.48
pmol/l
1.06
263
329
1290
9264
4.54
81.43
7.7
2.5
15.06
14.32
pmol/l
17.90
1223
8423
1170
8883
2.64
47.39
5.6
3.9
12.51
11.77
mm/h
1.14
1118
8230
1350
11223
3.91
43.22
8.8
3.4
1.81
2.01
mu/l
0.70
1282
10312
43
39
11.33
40.79
2.0
1.2
230.55
62.46
u/ml
—
16
5
414
2470
1.95
26.60
1.8
1.5
—
—
—
0
0
906
6898
1.83
26.46
8.2
8.9
4.01
4.01
e9/l
0.03
821
6020
744
5471
1.74
23.17
5.8
5.8
1.22
1.22
mmol/l
0.54
643
4672
82
253
3.38
21.97
1.3
1.2
—
—
—
0
0
1361
12216
2.84
21.74
15.7
12.3
19.26
22.08
mg/l
3.01
1172
9499
200
985
2.20
21.26
1.9
1.8
373.64
370.82
nmol/l
0.08
185
895
755
5720
1.67
19.86
5.9
5.7
29.58
28.46
%
2.00
713
5370
743
5646
1.65
18.99
5.8
5.5
56.06
56.93
%
1.16
703
5288
355
2241
1.77
18.02
1.4
1.3
29.22
34.19
iu/ml
0.29
111
735
661
4928
1.63
17.85
5.4
5.2
1.22
1.22
mmol/l
0.13
607
4509
511
3581
1.66
17.61
2.5
2.3
56.43
59.99
u/l
0.79
480
3311
407
2693
1.71
17.39
1.6
1.7
0.77
1.02
mg/l
1.89
306
2052
1077
9124
1.70
16.91
7.4
7.1
76.28
76.59
u/l
0.06
1020
8588
554
4059
1.59
15.43
3.4
3.2
26.24
44.07
ng/l
0.92
318
2544
463
3282
1.60
14.66
2.2
2.0
119.52
197.08
u/l
2.39
436
3104
693
5387
1.55
14.64
3.3
2.7
107.69
105.09
ug/l
0.07
640
5026
813
6586
1.53
13.94
4.3
4.1
6.37
6.55
mmol/l
2.05
775
6115
641
4972
1.52
13.23
2.4
2.2
79.36
77.74
nmol/l
0.76
592
4528
1343
12385
2.13
13.20
15.3
13.4
139.65
139.69
mmol/l
0.22
1323
12045
322
2134
1.65
13.18
1.4
1.3
9.91
11.51
u/ml
0.20
144
815
350
2381
1.62
12.87
1.5
1.4
2.15
2.30
g/l
1.20
215
1463
1344
12427
2.11
12.64
15.4
13.5
3.93
3.94
mmol/l
0.52
1319
12058
392
2769
1.57
12.20
1.3
1.2
0.95
1.34
u/ml
0.60
99
711
241
1521
1.70
11.77
2.2
2.3
77.42
105.26
ug/g
1.86
181
1191
732
5930
1.47
11.68
4.1
3.6
0.00
0.00
estimate
0.75
137
1148
740
6022
1.47
11.44
4.1
3.6
0.00
0.01
estimate
1.08
128
1052
732
5954
1.46
11.29
5.1
4.9
0.00
0.00
estimate
0.50
131
1074
512
3886
1.49
11.23
3.1
3.3
2.36
2.36
mmol/l
0.27
447
3453
136
740
1.92
10.84
3.5
3.7
75.70
84.05
ng/l
0.67
117
644
738
6047
1.45
10.74
5.5
5.9
9.91
10.77
umol/l
1.76
704
5750
929
7986
1.45
10.23
4.9
4.2
99.93
1922.41
e6/l
1.74
14
96
420
3118
1.49
10.06
4.5
3.9
0.00
0.01
estimate
1.08
133
1062
603
4809
1.43
9.89
4.1
4.4
36.59
35.88
g/l
2.69
549
4488
133
750
1.85
9.50
1.3
1.3
27.30
38.10
au/ml
—
5
46
143
826
1.81
9.45
2.4
2.3
14.91
22.63
au/ml
0.78
15
67
1373
13002
2.04
8.83
11.3
9.6
24.51
24.83
u/l
0.36
1338
12571
570
4573
1.41
8.72
4.0
3.7
—
—
—
0
0
601
4870
1.40
8.66
11.1
12.4
1.10
1.19
inr
2.89
201
1422
292
2067
1.52
8.64
4.0
3.3
123.92
333.85
ng/l
1.44
179
1443
349
2566
1.47
8.57
4.6
3.9
1.02
1.02
kg/l
0.03
49
360
1192
10908
1.52
8.39
5.5
5.1
38.66
38.95
mmol/mol
0.60
1117
10149
137
810
1.76
8.37
1.4
1.2
118.81
193.87
u/ml
0.95
132
741
315
2287
1.48
8.21
1.6
1.6
463.32
38232647.52
pmol/l
2.71
263
1912
942
8275
1.39
8.11
3.6
3.1
—
—
—
0
0
140
846
1.72
7.93
2.5
2.7
10.19
10.48
g/l
0.44
123
774
1265
11763
1.59
7.91
4.5
4.1
5.70
5.80
mmol/l
3.09
1184
10768
553
4476
1.38
7.79
1.9
1.9
102.08
96.45
pmol/l
1.73
266
2256
367
2774
1.43
7.68
2.6
2.7
706.64
1158.26
ng/l
1.95
311
2319
284
2050
1.48
7.56
2.7
2.9
2.43
2.45
mmol/l
2.48
246
1806
362
2737
1.43
7.55
2.2
2.1
2.52
2.99
mg/l
4.77
309
2346
1161
10672
1.44
7.01
17.8
14.7
14.71
14.80
%
0.21
1147
10481
88
486
1.86
6.75
1.2
1.3
0.28
1.68
u/ml
1.25
16
37
391
3058
1.38
6.58
2.9
2.8
0.29
0.48
e6/l
1.74
307
2245
305
2289
1.42
6.53
2.4
2.4
5.93
6.70
e6/l
0.34
269
2029
85
472
1.85
6.42
1.8
2.0
36.59
39.47
u/l
0.74
76
424
422
3354
1.36
6.40
3.1
2.9
100.35
91.63
e6/l
0.05
331
2489
1279
12037
1.53
6.31
4.5
4.1
4.83
4.82
mmol/l
0.19
1203
11222
1297
12245
1.56
6.29
5.0
4.5
2.89
2.85
mmol/l
0.96
1218
11363
1272
11980
1.50
6.01
4.4
4.0
1.53
1.54
mmol/l
0.37
1194
11122
68
359
1.94
6.01
1.6
1.3
—
—
—
0
0
74
402
1.89
6.00
1.6
2.0
—
—
—
0
0
1228
11506
1.44
5.78
12.9
11.3
83.47
83.59
ml/min/173m2
0.07
1044
9396
66
351
1.92
5.72
1.3
1.3
—
—
—
0
0
65
344
1.93
5.71
1.3
1.1
—
—
—
0
0
1410
13659
2.14
5.68
22.7
18.2
40.12
39.70
%
2.67
1340
12851
478
3929
1.32
5.66
2.9
3.1
28.63
31.05
u/l
1.31
465
3741
1411
13674
2.16
5.65
22.9
18.1
261.01
259.10
e9/l
0.56
1395
13323
40
177
2.30
5.59
1.1
1.1
—
—
—
0
0
1411
13682
2.13
5.51
22.8
18.1
4.47
4.45
e12/l
0.81
1389
13292
165
1136
1.51
5.48
3.7
4.3
224.59
250.94
u/l
1.41
158
1076
1411
13689
2.12
5.38
22.9
18.2
133.89
133.68
g/l
0.26
1401
13493
1410
13680
2.09
5.31
22.8
18.2
6.67
6.64
e9/l
0.18
1390
13285
125
817
1.58
5.25
2.4
2.8
67.51
67.16
g/l
0.22
113
750
1225
11521
1.41
5.20
4.0
3.6
1.23
1.25
mmol/l
0.58
1146
10616
111
709
1.61
5.14
1.3
1.3
26.40
30.35
iu/l
0.59
93
610
230
1712
1.41
5.09
2.7
3.2
0.83
0.82
mmol/l
0.73
213
1624
57
303
1.92
4.98
1.8
2.0
9.15
12.36
mg/l
1.77
50
280
50
258
1.97
4.77
1.9
1.2
10.72
12.46
u/l
0.39
45
206
75
442
1.73
4.72
1.7
1.4
309.32
287.71
mu/l
0.23
63
398
243
1855
1.37
4.61
2.5
2.5
1.07
1.33
e6/l
0.35
150
989
65
371
1.79
4.57
1.4
1.5
0.02
0.06
iu/ml
0.73
16
76
43
214
2.04
4.55
1.0
1.1
3.85
4.51
u/ml
0.15
19
108
352
2851
1.31
4.47
2.3
2.4
874.74
5031.59
umol/l
4.70
312
2521
309
2461
1.32
4.42
1.6
1.5
21.52
21.18
nmol/l
0.15
266
2104
220
1664
1.38
4.41
1.7
1.8
—
—
—
0
0
202
1513
1.39
4.30
2.3
2.2
2.42
2.37
g/l
0.67
186
1406
20
73
2.76
4.19
2.1
2.4
—
—
—
0
0
128
887
1.49
4.15
3.0
3.1
1.23
1.23
mmol/l
0.12
107
777
68
407
1.70
4.09
2.7
2.2
7.45
7.44
g/l
0.01
59
373
173
1277
1.40
4.01
4.5
5.1
1.01
1.04
mmol/l
0.73
164
1196
175
1297
1.40
3.97
2.4
2.8
4.82
7.78
umol/l
3.40
146
1118
63
374
1.72
3.91
2.6
2.2
9.67
10.27
g/l
0.54
53
339
40
206
1.97
3.89
1.0
1.0
2.65
1.23
u/ml
0.24
16
97
64
383
1.70
3.87
2.8
2.3
2.77
2.96
g/l
0.98
55
349
26
113
2.32
3.86
1.1
1.2
—
—
—
0
0
67
407
1.68
3.83
2.7
2.2
—
—
—
0
0
67
407
1.68
3.83
2.7
2.2
3.51
3.61
g/l
0.35
57
373
10
19
5.29
3.83
1.2
1.1
90.00
97.16
%
—
10
19
118
820
1.48
3.79
2.0
2.2
4.49
6.48
ug/l
1.29
104
722
33
162
2.06
3.67
1.0
1.0
3.44
6.08
u/ml
0.37
11
58
215
1668
1.34
3.66
2.4
2.2
13.83
13.31
umol/l
0.41
199
1556
179
1355
1.37
3.58
2.0
2.0
—
—
—
0
0
157
1164
1.39
3.56
1.6
1.7
—
—
—
0
0
154
1142
1.39
3.49
1.6
1.7
—
—
—
0
0
67
420
1.62
3.43
2.7
1.9
9.99
11.33
nmol/l
0.59
62
374
84
556
1.54
3.42
2.8
2.0
4952.63
4688.79
u/l
0.03
39
229
195
1513
1.33
3.32
2.2
2.1
—
—
—
0
0
57
346
1.67
3.31
2.9
2.3
0.60
0.79
g/l
0.21
47
310
14
48
2.94
3.30
1.0
1.2
—
—
—
0
0
183
1408
1.34
3.30
2.4
2.3
23.30
22.93
%
0.10
154
1218
231
1840
1.30
3.27
1.5
1.7
1281.77
1213.36
nmol/l
0.51
175
1384
38
206
1.87
3.23
1.1
1.1
—
—
—
0
0
33
171
1.95
3.20
1.4
1.3
—
—
—
0
0
106
749
1.45
3.17
1.7
1.6
—
—
—
0
0
147
1101
1.37
3.15
2.4
2.2
56.24
39.61
u/l
0.33
126
937
53
320
1.68
3.15
2.9
2.1
38.61
37.89
g/l
0.36
45
286
634
5680
1.21
3.09
2.5
2.5
—
—
—
0
0
22
99
2.24
3.07
1.1
1.1
0.01
0.32
u/ml
1.59
12
43
34
181
1.90
3.07
1.0
1.0
5.10
2.89
u/ml
0.19
12
79
13
41
3.19
3.06
1.2
1.2
—
—
—
0
0
32
168
1.93
3.01
1.9
1.5
48.19
43.06
nmol/l
0.39
32
162
61
389
1.59
2.95
1.6
1.7
—
—
—
0
0
43
250
1.74
2.94
1.1
1.1
0.28
2.45
u/ml
2.94
18
125
51
311
1.66
2.94
3.1
2.2
0.00
0.00
g/l
0.50
45
289
86
598
1.47
2.82
6.1
6.8
24.75
24.54
mmol/l
0.28
81
567
48
292
1.67
2.81
2.8
3.5
124.81
46.48
mg/l
0.34
43
238
48
292
1.67
2.81
2.8
3.5
977.38
82.14
mg/l
0.46
43
239
74
501
1.50
2.77
1.1
1.1
—
1.06
—
0
5
215
1735
1.28
2.76
2.9
2.6
3.15
3.46
e6/l
0.23
126
878
8
19
4.23
2.68
1.0
1.1
—
—
—
0
0
202
1631
1.28
2.58
1.6
1.9
29.69
29.40
s
0.21
194
1572
381
3299
1.21
2.57
3.0
3.0
7.15
7.23
mmol/l
0.13
325
2800
127
963
1.35
2.56
2.2
1.8
—
—
—
0
0
64
428
1.52
2.56
1.5
2.0
1.38
1.52
g/l
0.62
53
373
46
286
1.63
2.51
3.1
2.2
0.00
0.00
g/l
-0.00
40
266
45
282
1.61
2.39
3.2
2.3
0.00
0.00
g/l
-0.00
40
265
33
190
1.75
2.38
1.3
1.4
—
—
—
0
0
33
190
1.75
2.38
1.3
1.4
—
—
—
0
0
27
146
1.87
2.38
1.0
1.0
0.03
0.20
u/ml
—
8
43
38
228
1.68
2.38
2.5
2.4
44.99
87.58
ug/min
0.62
28
136
12
46
2.62
2.36
1.9
3.3
587.75
907.09
u/ml
0.64
12
46
10
33
3.04
2.36
5.6
3.9
—
—
—
0
0
30
169
1.79
2.33
1.2
1.2
0.51
0.61
nmol/l
1.81
30
158
42
264
1.61
2.22
1.3
1.5
—
—
—
0
0
366
3199
1.19
2.21
1.7
1.6
1.32
1.36
mmol/l
0.48
296
2744
75
536
1.42
2.19
3.0
2.5
0.07
0.29
e6/l
3.28
67
516
322
2785
1.20
2.18
1.5
1.5
—
—
—
0
0
8
24
3.35
2.18
2.9
3.3
—
—
—
0
0
8
24
3.35
2.18
2.9
3.3
—
—
—
0
0
15
67
2.25
2.18
1.1
1.1
—
—
—
0
0
36
220
1.65
2.13
2.3
1.6
—
—
—
0
0
862
8085
1.16
2.12
3.2
2.9
38.83
43.64
u/l
1.38
814
7572
15
68
2.22
2.11
1.0
1.0
—
—
—
0
0
139
1101
1.29
2.10
1.9
2.6
1.71
1.83
%
0.79
122
983
11
43
2.57
2.08
1.0
1.0
—
—
—
0
0
5
10
5.01
2.07
1.0
1.0
—
—
—
0
0
5
10
5.01
2.07
1.0
1.1
—
—
—
0
0
29
169
1.73
2.05
1.2
1.2
—
0.41
nmol/l
—
0
8
10
39
2.57
1.94
1.1
2.0
6.35
10.63
mg/l
—
10
31
6
16
3.76
1.93
1.0
1.4
—
—
—
0
0
24
135
1.79
1.92
1.4
1.3
—
—
—
0
0
24
135
1.79
1.92
1.4
1.3
—
—
—
0
0
16
78
2.06
1.91
1.5
1.1
—
—
—
0
0
43
284
1.53
1.88
2.9
3.5
1.24
2.16
ratio
—
6
22
31
189
1.65
1.88
1.8
1.3
20.77
26.63
u/l
0.48
24
158
35
221
1.60
1.86
5.1
6.2
104.27
105.07
mmol/l
0.34
30
199
100
773
1.32
1.83
2.1
2.5
103.55
161.46
ng/l
1.18
92
693
332
2924
1.18
1.82
3.2
3.6
97.72
94.47
%
1.99
324
2852
12
53
2.27
1.81
1.3
2.1
21.61
170.60
ug/l
0.48
12
46
78
584
1.35
1.78
1.5
1.7
—
—
—
0
0
66
481
1.39
1.77
3.2
3.0
25.34
25.39
mmol/l
0.06
66
468
51
356
1.45
1.74
1.1
1.1
0.66
3.67
u/ml
—
7
47
11
48
2.30
1.70
1.1
1.0
2431.01
1577.54
miu/ml
1.28
11
48
17
89
1.92
1.70
1.1
1.3
—
—
—
0
0
81
617
1.33
1.66
1.4
1.5
—
—
—
0
0
7
25
2.81
1.65
1.1
1.2
—
—
—
0
0
16
83
1.94
1.65
1.3
2.2
—
—
—
0
0
90
699
1.31
1.62
1.1
1.0
—
—
—
0
0
342
3047
1.16
1.61
3.3
3.1
240.20
324.73
mg/l
0.19
198
1844
13
63
2.07
1.60
1.4
1.3
31.82
37.68
nmol/l
0.32
13
51
39
263
1.50
1.59
1.4
1.5
—
—
—
0
0
95
746
1.29
1.58
2.0
1.7
—
—
—
0
0
47
333
1.43
1.51
1.2
1.2
2.43
4.79
u/ml
—
6
62
26
162
1.62
1.50
1.2
1.1
—
—
—
0
0
55
403
1.38
1.47
3.7
4.6
1.74
1.54
%
0.42
49
378
31
204
1.53
1.43
1.2
1.4
142.80
112.73
u/ml
—
9
42
31
205
1.52
1.41
1.4
1.3
—
—
—
0
0
156
1316
1.21
1.41
5.3
4.2
20.49
21.07
%
0.21
82
605
16
89
1.81
1.37
1.1
1.1
—
—
—
0
0
16
89
1.81
1.37
1.1
1.1
—
—
—
0
0
16
90
1.79
1.33
1.1
1.1
—
—
—
0
0
16
90
1.79
1.33
1.1
1.1
—
—
—
0
0
16
90
1.79
1.33
1.1
1.1
—
—
—
0
0
23
144
1.61
1.32
1.3
1.3
—
—
—
0
0
111
913
1.23
1.30
2.3
2.2
69.00
71.00
ml/min/173m2
0.21
40
354
29
193
1.51
1.30
2.0
2.3
4.05
5.19
umol/l
0.67
24
135
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
114
942
1.23
1.28
7.2
7.4
123.99
119.75
g/l
1.58
109
918
56
423
1.34
1.27
1.6
1.7
—
—
—
0
0
8
35
2.29
1.27
1.4
1.3
—
—
—
0
0
352
3198
1.13
1.25
3.8
3.6
10.56
9.09
mg/mmol
0.13
206
1930
17
100
1.71
1.23
1.9
1.4
45.08
30.32
%
0.70
12
62
42
305
1.39
1.22
1.4
1.4
—
—
—
0
0
6
26
2.31
1.18
1.0
1.5
—
—
—
0
0
19
117
1.63
1.18
1.2
1.5
—
—
—
0
0
26
175
1.49
1.13
1.4
1.3
—
—
—
0
0
8
40
2.01
1.12
1.1
1.1
256.63
209.74
iu/ml
—
8
40
145
1248
1.18
1.09
6.6
6.4
105.03
104.21
mmol/l
1.50
145
1248
8
41
1.96
1.09
2.1
1.5
7.42
8.78
ug/l
—
8
41
15
91
1.66
1.00
1.1
1.2
—
—
—
0
0
158
1381
1.16
1.00
6.4
6.1
—
—
—
0
0
43
326
1.33
1.00
1.5
2.3
474.22
486.62
ug/l
0.01
38
300
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
38
285
1.34
0.95
2.3
3.2
0.51
0.39
u/ml
0.46
22
156
33
242
1.37
0.95
2.8
3.5
16.98
26.10
mg/l
1.25
20
156
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
62
1.78
0.94
1.3
1.1
—
—
—
0
0
15
93
1.62
0.94
1.2
1.5
—
—
—
0
0
37
278
1.34
0.92
1.6
1.7
8790.43
11483.54
e6/l
0.30
30
206
34
253
1.35
0.90
1.5
1.5
4656.55
1508.64
e6/l
0.30
29
201
34
253
1.35
0.90
1.4
1.5
97.44
13.94
e6/l
0.42
27
187
38
288
1.33
0.90
2.2
2.6
—
—
—
0
0
11
64
1.72
0.86
1.1
1.2
—
—
—
0
0
24
172
1.40
0.81
1.5
1.3
5.96
7.24
mmol/l
1.98
19
147
15
98
1.54
0.78
1.3
1.6
—
—
—
0
0
31
234
1.33
0.78
1.1
1.2
—
—
—
0
0
20
140
1.43
0.77
1.7
1.5
—
—
—
0
0
20
140
1.43
0.77
1.7
1.5
—
—
—
0
0
52
422
1.24
0.76
1.8
1.9
—
—
—
0
0
20
141
1.42
0.74
1.7
1.5
—
—
—
0
0
20
141
1.42
0.74
1.7
1.5
—
—
—
0
0
9
54
1.67
0.74
1.8
2.1
—
—
—
0
0
9
54
1.67
0.74
1.3
1.1
—
—
—
0
0
7
38
1.85
0.73
1.3
1.4
—
—
—
0
0
9
55
1.64
0.73
1.0
1.7
—
—
—
0
0
9
55
1.64
0.73
1.0
1.7
—
—
—
0
0
104
906
1.16
0.73
3.9
3.7
1.81
1.89
mmol/l
0.10
94
761
10
159
0.63
0.72
4.3
5.2
363.40
365.64
umol/l
—
10
135
10
60
1.67
0.72
1.3
1.3
—
1314.00
—
0
5
46
372
1.24
0.71
2.1
1.9
1.43
2.15
ug/l
0.34
36
329
129
1145
1.14
0.70
7.1
6.7
1.04
1.15
mmol/l
0.14
105
905
20
143
1.40
0.70
1.7
1.5
—
—
—
0
0
7
41
1.71
0.70
2.4
1.2
186.73
143.23
pmol/l
—
7
41
5
27
1.85
0.68
1.0
1.0
—
—
—
0
0
7
43
1.63
0.67
1.4
1.2
—
—
—
0
0
38
304
1.26
0.65
1.4
1.5
297.00
303.00
ug/g
0.06
21
169
0
20
0.00
0.60
0.0
1.9
—
7.38
—
0
11
32
254
1.27
0.60
1.5
1.4
—
—
—
0
0
12
80
1.50
0.60
1.2
1.4
—
—
—
0
0
28
219
1.28
0.58
1.8
1.5
—
—
—
0
0
26
202
1.29
0.57
1.3
1.2
3.00
3.10
u/ml
—
9
60
14
98
1.43
0.56
1.2
1.5
—
—
—
0
0
14
98
1.43
0.56
1.2
1.5
—
—
—
0
0
14
98
1.43
0.56
1.2
1.5
—
—
—
0
0
53
449
1.19
0.55
1.5
1.3
210.59
245.10
miu/ml
0.32
24
217
19
142
1.34
0.54
1.7
1.5
—
—
—
0
0
28
222
1.27
0.54
1.2
1.2
395.60
257.94
u/ml
0.43
20
138
73
638
1.15
0.53
1.6
1.5
—
—
—
0
0
178
1642
1.10
0.53
5.7
4.8
3.54
2.29
ug/l
0.36
163
1464
22
170
1.30
0.51
2.5
2.1
63.26
62.47
%
0.07
22
170
19
144
1.32
0.50
1.9
2.2
16.00
25.72
mg/l
—
5
42
126
1146
1.11
0.50
7.1
6.7
4.95
5.10
kpa
1.19
119
1101
126
1146
1.11
0.50
7.1
6.7
12.84
12.82
kpa
0.01
119
1100
302
2855
1.07
0.50
2.3
2.1
—
—
—
0
0
23
180
1.28
0.49
1.2
1.1
139.67
3372.01
iu/ml
—
9
38
45
381
1.19
0.49
1.9
1.7
—
—
—
0
0
7
45
1.56
0.49
1.3
1.4
—
—
—
0
0
26
208
1.25
0.48
1.5
1.7
—
—
—
0
0
107
968
1.11
0.47
3.2
2.9
0.66
0.74
ug/l
0.75
72
629
19
146
1.31
0.47
1.2
1.4
—
—
—
0
0
12
85
1.42
0.47
1.3
1.3
75.17
76.00
umol/l
0.05
12
85
23
183
1.26
0.45
1.2
1.1
—
—
—
0
0
34
403
0.84
0.42
1.6
1.4
—
—
—
0
0
5
32
1.56
0.42
1.6
1.1
—
—
—
0
0
51
444
1.15
0.42
3.8
3.4
44.08
47.49
%
0.45
51
438
34
402
0.84
0.41
1.6
1.4
—
—
—
0
0
34
402
0.84
0.41
1.6
1.4
—
—
—
0
0
5
33
1.52
0.41
1.6
1.5
35.40
26.78
%
—
5
23
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
5
33
1.52
0.41
1.6
2.2
—
—
—
0
0
5
33
1.52
0.41
1.6
1.1
—
—
—
0
0
37
314
1.18
0.41
1.7
1.6
—
—
—
0
0
14
105
1.34
0.41
1.1
1.1
—
—
—
0
0
34
401
0.84
0.40
1.6
1.4
—
—
—
0
0
7
102
0.68
0.39
1.3
1.1
—
53.38
—
0
8
7
101
0.69
0.39
1.3
1.1
—
43.40
—
0
5
5
35
1.43
0.39
1.6
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
70
627
1.12
0.39
8.7
8.4
93.60
94.17
%
0.28
70
622
22
178
1.24
0.39
1.2
1.2
—
—
—
0
0
5
36
1.39
0.38
1.6
1.1
—
—
—
0
0
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
34
289
1.18
0.38
1.1
1.3
—
—
—
0
0
5
37
1.35
0.37
1.4
1.1
—
—
—
0
0
5
77
0.65
0.35
2.0
1.6
—
—
—
0
0
6
45
1.33
0.33
1.5
1.3
—
—
—
0
0
6
46
1.31
0.33
1.5
1.3
—
—
—
0
0
14
110
1.28
0.31
1.2
1.5
—
—
—
0
0
120
1120
1.08
0.31
2.7
3.1
—
—
—
0
0
10
75
1.34
0.30
1.3
1.1
—
—
—
0
0
27
231
1.17
0.30
3.9
3.4
55.41
58.03
%
0.71
27
231
25
213
1.18
0.29
1.2
1.3
—
—
—
0
0
25
213
1.18
0.29
1.7
1.4
—
—
—
0
0
25
213
1.18
0.29
1.2
1.3
—
—
—
0
0
57
518
1.10
0.27
1.6
1.7
5.78
4.35
mg/l
0.26
46
378
43
477
0.90
0.25
1.6
1.4
—
—
—
0
0
9
75
1.20
0.25
2.3
1.2
—
—
—
0
0
42
379
1.11
0.24
1.2
1.2
—
—
—
0
0
22
190
1.16
0.23
1.2
1.5
—
—
—
0
0
5
40
1.25
0.22
1.6
1.4
—
—
—
0
0
5
40
1.25
0.22
1.6
1.4
—
—
—
0
0
7
94
0.74
0.22
1.3
1.1
—
2.67
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
17
145
1.17
0.20
2.4
3.5
14.58
51.52
u/ml
2.03
17
145
11
90
1.22
0.19
1.2
1.4
—
—
—
0
0
6
52
1.15
0.19
1.5
1.4
—
—
—
0
0
6
53
1.13
0.18
1.5
1.4
—
—
—
0
0
22
194
1.14
0.18
2.6
2.2
15.48
16.36
%
—
5
90
7
58
1.21
0.18
1.7
1.6
—
—
—
0
0
40
435
0.92
0.18
1.6
1.5
—
—
—
0
0
7
63
1.11
0.17
1.3
1.1
66.43
75.57
u/l
—
7
53
67
709
0.94
0.16
1.5
1.4
—
—
—
0
0
13
111
1.17
0.15
1.1
1.1
—
—
—
0
0
6
80
0.75
0.15
1.3
1.1
—
—
—
0
0
10
83
1.21
0.15
1.3
1.2
—
—
—
0
0
9
79
1.14
0.15
1.3
1.5
—
—
—
0
0
44
410
1.08
0.15
2.4
3.3
83.88
559.83
u/ml
0.78
36
351
56
594
0.94
0.14
1.6
1.5
—
—
—
0
0
8
98
0.82
0.13
1.9
1.5
0.91
0.95
g/l
—
8
98
9
110
0.82
0.13
2.2
2.7
—
—
—
0
0
21
190
1.11
0.12
1.1
1.0
1.16
2.24
u/ml
—
10
87
121
1171
1.04
0.12
1.8
1.6
—
—
—
0
0
22
201
1.10
0.11
1.3
1.2
3.00
2.64
u/ml
—
8
77
38
357
1.07
0.11
1.6
1.5
—
—
—
0
0
17
188
0.90
0.11
3.1
1.9
13.22
13.17
%
0.07
17
188
40
377
1.06
0.11
1.3
1.2
—
—
—
0
0
23
249
0.92
0.10
1.3
1.6
—
—
—
0
0
147
1434
1.03
0.10
4.4
4.2
32.93
32.62
%
0.13
114
962
5
44
1.14
0.10
1.0
1.9
—
—
—
0
0
5
44
1.14
0.10
1.0
1.9
—
—
—
0
0
5
44
1.14
0.10
1.0
1.9
—
—
—
0
0
14
126
1.11
0.09
1.2
2.0
29.64
31.84
pg
0.65
14
126
15
165
0.91
0.09
1.1
1.2
—
—
—
0
0
18
165
1.09
0.08
1.4
1.1
—
—
—
0
0
48
459
1.05
0.08
4.2
4.1
24.78
24.09
mmol/l
0.93
48
452
5
65
0.77
0.08
1.8
1.5
1.37
1.39
nmol/l
—
5
50
31
293
1.06
0.08
2.0
1.5
—
—
—
0
0
7
67
1.05
0.08
1.1
1.1
—
—
—
0
0
15
137
1.10
0.07
2.5
2.3
—
—
—
0
0
9
84
1.07
0.07
1.4
1.5
—
—
—
0
0
9
87
1.03
0.07
1.3
1.2
—
—
—
0
0
10
89
1.12
0.07
1.3
1.2
—
—
—
0
0
45
433
1.04
0.06
2.6
1.8
—
—
—
0
0
72
740
0.97
0.06
1.6
1.5
—
—
—
0
0
116
1177
0.98
0.04
3.3
4.1
8.15
23.80
ug/l
1.17
92
941
139
1375
1.01
0.03
1.8
1.7
1.32
1.40
%
1.11
129
1207
54
529
1.02
0.03
2.4
3.5
1.52
1.77
mmol/l
0.26
45
405
27
262
1.03
0.02
1.6
1.4
—
—
—
0
0
22
227
0.97
0.01
2.1
2.1
130.00
129.74
g/l
0.02
15
155
12
114
1.05
0.00
1.3
1.5
—
—
—
0
0
14
142
0.99
0.00
1.0
1.1
—
—
—
0
0
21
209
1.00
0.00
4.7
3.4
548.26
1813.94
u/ml
0.47
21
194
15
153
0.98
0.00
1.3
1.4
—
—
—
0
0
13
125
1.04
0.00
1.1
1.1
—
—
—
0
0
11
115
0.96
0.00
5.4
3.6
—
—
—
0
0
5
50
1.00
0.00
1.0
1.1
85.20
95.98
%
—
5
43
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
8.67
—
0
7
6
62
0.97
-0.00
1.5
1.4
—
—
—
0
0
8
86
0.93
-0.00
2.0
1.3
1.55
1.61
g/l
—
8
86
5
54
0.93
-0.00
1.6
3.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
37.43
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
21.90
—
0
7
6
63
0.95
-0.00
1.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
2.43
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
-0.00
1.2
5.4
—
92.27
—
0
11
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
5.56
—
0
5
6
61
0.98
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.2
1.1
24.83
15.79
u/l
—
6
52
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_THYROIDITSUBAC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYROIDITSUBAC | 0.833 [0.71, 0.98] | 0.025 |
| Birth year | 0.993 [0.98, 1.0] | 0.139 |
During the follow-up period (1.1.1998 — 31.12.2019), 208 out of 4418 females with E4_THYROIDITSUBAC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYROIDITSUBAC | 0.597 [0.48, 0.74] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 1239 males with E4_THYROIDITSUBAC died.
Mortality risk
Mortality risk for people of age
years, who have E4_THYROIDITSUBAC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.066% | 0.092% |
| 5 | 0.527% | 0.625% |
| 10 | 1.263% | 1.65% |
| 15 | 2.331% | 3.15% |
| 20 | 4.065% | 5.585% |
Relationships between endpoints
↥Index endpoint: E4_THYROIDITSUBAC – Subacute thyroiditis
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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