No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
151 |
4. Check minimum number of eventsNone |
151 |
5. Include endpointsNone |
151 |
6. Filter based on genotype QC (FinnGen only) |
151 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E06
- Name in latin
- Thyreoiditis acuta
Similar endpoints
↥List of similar endpoints to
Acute thyroiditis
based on the number of shared cases.
Similar with more cases:
- Thyroiditis
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1138 | 842 | 289 |
| Only index persons | 1081 | 812 | 269 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.03 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 46.43 | 45.51 | 49.44 |
| Only index persons | 45.78 | 44.95 | 48.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 151 | 116 | 35 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.02 |
| Median age at first event (years) | 46.66 | 45.10 | 51.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 135
- Matched controls
- 1350
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E06.0
ICD-10 Finland
Acute thyroiditis
+∞
174.6
127
*
H03AA01
ATC
levothyroxine sodium; systemic
76.6
59.0
65
16
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
33.8
31
*
104
Kela drug reimbursment
Thyroid insufficiency
304.0
25.6
25
*
H03BB01
ATC
carbimazole; oral
289.2
24.5
24
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
45.7
19.3
23
6
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
+∞
19.2
18
*
E06.9
ICD-10 Finland
Thyroiditis, unspecified
+∞
15.9
15
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
13.7
15.1
26
23
BAA60
NOMESCO Finland
Total thyroidectomy
+∞
14.9
14
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
142.7
12.7
13
*
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
71.3
11.8
13
*
H02AB06
ATC
prednisolone; systemic
3.2
9.8
82
436
E03.89
ICD-10 Finland
Other specified hypothyroidism
+∞
9.5
9
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
+∞
9.5
9
*
H02AB07
ATC
prednisone; oral
4.2
8.6
34
99
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
95.8
8.5
9
*
E06.3
ICD-10 Finland
Autoimmune thyroiditis
+∞
7.4
7
*
2450A
ICD-9 Finland
Thyroiditis, Acute thyroiditis
+∞
7.4
7
*
T86
ICPC
Hypothyroidism/myxoedema
42.2
6.8
8
*
J01FA06
ATC
roxithromycin; oral
2.6
6.5
68
380
C07AA05
ATC
propranolol; systemic
3.0
6.2
40
165
R03AC02
ATC
salbutamol; inhalant
2.5
6.2
84
536
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
29
68
5.04
12.11
1.3
1.2
iu/ml
148.3
126.1
—
10
24
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
127
919
3.40
7.55
7.8
2.6
pmol/l
15.5
14.4
2.65
121
828
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
48
267
2.17
4.40
2.9
2.0
mg/l
2.9
2.8
0.01
43
233
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
136
1140
2.94
4.10
8.7
3.3
mu/l
1.6
1.8
1.54
128
1038
(3036481) Cortisol [Moles/volume] in Serum or Plasma
24
102
2.61
3.99
2.1
2.0
nmol/l
405.3
361.5
0.31
24
90
(3022948) Iron [Moles/volume] in Serum or Plasma
33
171
2.19
3.55
2.5
1.7
umol/l
13.3
14.4
0.38
28
158
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
9
18
5.24
3.43
1.3
1.3
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
66
444
1.86
3.40
9.3
7.5
inr
1.3
1.2
0.44
20
137
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
65
438
1.85
3.31
2.1
1.8
pmol/l
108.9
92.6
1.44
34
209
(3037522) Nuclear Ab [Titer] in Serum
31
161
2.16
3.30
1.4
1.4
titre
822.2
515.0
—
9
40
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
78
562
1.80
3.15
6.1
5.2
mmol/l
1.2
1.2
0.55
64
480
(3013826) Glucose [Moles/volume] in Serum or Plasma
92
699
1.81
3.09
4.5
4.0
mmol/l
6.8
6.4
0.98
87
644
(3037467) Urinalysis macro (dipstick) panel - Urine
106
848
1.84
2.92
4.6
4.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
53
348
1.81
2.86
4.6
2.9
ph
7.4
7.4
0.03
12
66
(42870588) Differential panel, method unspecified - Blood
57
383
1.78
2.85
7.6
4.8
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
113
929
1.86
2.77
5.6
3.9
mm/h
13.9
10.4
1.92
106
845
(3007853) Bacteria identified in Skin by Aerobe culture
25
128
2.14
2.75
1.9
1.6
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
115
953
1.87
2.72
8.7
6.7
u/l
74.6
76.1
0.13
110
888
(3001604) Monocytes [#/volume] in Blood
81
608
1.72
2.71
7.3
5.2
e9/l
0.5
0.5
0.12
75
535
(3006315) Basophils [#/volume] in Blood
81
609
1.71
2.68
7.3
5.2
e9/l
0.0
0.0
0.04
76
536
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
69
500
1.70
2.59
5.8
4.6
mmol/l
1.2
1.2
0.15
64
462
(3002030) Lymphocytes/100 leukocytes in Blood
78
585
1.69
2.57
8.2
5.1
%
28.2
28.3
0.03
72
554
(3019198) Lymphocytes [#/volume] in Blood
81
619
1.67
2.45
7.4
5.3
e9/l
1.9
1.9
0.11
76
557
(3009508) Creatinine [Moles/volume] in Urine
48
319
1.74
2.44
5.0
2.7
mmol/l
8.0
7.3
0.35
41
260
(3018010) Neutrophils/100 leukocytes in Blood
76
573
1.66
2.41
8.3
5.0
%
57.3
57.2
0.05
70
547
(3006504) Eosinophils/100 leukocytes in Blood
76
574
1.65
2.39
8.2
5.0
%
2.6
2.7
0.06
71
540
(3015377) Calcium [Moles/volume] in Serum or Plasma
55
382
1.69
2.38
2.3
3.2
mmol/l
2.3
2.4
0.77
46
341
(3013115) Eosinophils [#/volume] in Blood
82
632
1.65
2.37
7.4
5.6
e9/l
0.2
0.2
0.54
77
569
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
27
152
1.95
2.31
3.1
1.6
%
21.8
24.1
0.34
19
132
(3023420) DNA double strand Ab [Units/volume] in Serum
6
13
4.76
2.29
1.0
1.2
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
6
13
4.76
2.29
1.3
1.1
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
15
67
2.38
2.26
1.2
1.3
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
36
226
1.78
2.21
1.3
1.3
u/ml
2.5
12.0
2.24
11
97
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
7
19
3.81
2.18
1.4
1.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
37
238
1.73
2.08
1.2
1.3
iu/ml
10.9
31.0
—
10
85
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
14
63
2.35
2.08
1.4
1.5
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
27
162
1.81
1.91
3.0
1.8
ug/g
74.0
110.7
0.58
22
122
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
51
367
1.59
1.86
2.2
2.3
u/l
52.1
54.7
0.35
46
343
(3000494) Fungus identified in Specimen by Culture
24
140
1.85
1.85
1.6
1.3
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
137
1247
2.06
1.84
4.6
4.0
mmol/l
1.5
1.6
2.08
129
1152
(3020682) Albumin/Creatinine [Ratio] in Urine
44
306
1.62
1.84
4.0
3.6
mg/mmol
1.6
9.8
2.91
32
182
(3013512) EKG study
47
333
1.60
1.82
3.5
3.5
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
10
41
2.54
1.79
1.1
1.1
—
—
—
0
0
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
5
13
3.94
1.73
1.0
1.3
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
137
1254
2.00
1.70
4.7
4.1
mmol/l
4.8
4.8
0.06
128
1164
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
81
656
1.51
1.69
5.5
5.5
umol/l
10.3
10.3
0.01
76
621
(3017143) Hepatitis C virus Ab [Presence] in Serum
23
137
1.80
1.67
1.6
1.4
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
7
25
2.88
1.67
3.0
2.0
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
5
14
3.65
1.63
1.4
1.9
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
24
147
1.75
1.59
1.8
1.9
—
—
—
0
0
(3008898) HLA-B27 [Presence]
13
64
2.13
1.59
1.0
1.0
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
134
1227
1.82
1.52
4.8
4.0
mmol/l
5.9
5.8
0.64
126
1132
(3012516) Albumin [Mass/volume] in Urine
41
293
1.55
1.51
3.6
3.0
mg/l
14.9
279.9
0.61
29
181
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
58
447
1.48
1.50
3.1
3.6
ng/l
47.3
25.5
0.31
33
286
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
36
250
1.58
1.50
1.9
1.6
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
22
134
1.75
1.49
1.7
1.9
—
—
—
0
0
(3017766) Complement C4 [Mass/volume] in Serum or Plasma
9
39
2.39
1.46
1.3
1.7
g/l
0.2
0.2
—
9
39
(3022621) pH of Urine by Test strip
16
89
1.89
1.43
2.4
2.5
—
—
—
0
0
(3002256) Pathology report gross observation
24
152
1.69
1.43
1.5
1.2
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
21
128
1.74
1.42
1.7
1.9
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
131
1198
1.71
1.41
14.1
11.1
ml/min/173m2
84.4
84.8
0.08
116
968
(3015736) pH of Urine
61
480
1.45
1.41
3.0
3.3
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
9
41
2.27
1.39
2.2
2.0
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
45
334
1.49
1.39
2.1
1.6
mmol/l
1.5
1.3
0.68
38
280
(3035350) Ketones [Presence] in Urine by Test strip
75
615
1.44
1.38
3.3
3.5
estimate
0.0
0.0
—
10
122
(3018095) Leukocytes [#/volume] in Urine
55
426
1.46
1.37
2.9
3.4
e6/l
28.0
54.7
0.65
35
284
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
17
3.00
1.37
1.0
1.2
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
31
213
1.57
1.35
1.7
1.5
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
137
1272
1.83
1.34
5.3
4.5
mmol/l
2.9
2.8
0.67
127
1171
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
9
43
2.16
1.33
1.3
1.6
g/l
1.3
1.2
—
9
43
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
5
18
2.84
1.29
1.0
1.2
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
5
18
2.84
1.29
1.6
1.2
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
53
412
1.44
1.29
2.4
2.8
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
6
26
2.36
1.20
1.2
2.1
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
16
95
1.77
1.19
1.1
1.1
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
27
185
1.56
1.19
1.7
1.9
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
142
1348
1.90
1.17
13.1
9.3
u/l
25.5
24.8
0.26
135
1299
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
30
212
1.52
1.16
3.6
3.2
ng/l
31.0
104.9
1.27
21
152
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
130
1203
1.58
1.13
4.1
3.7
mmol/l
1.3
1.2
0.96
123
1111
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
21
2.43
1.10
1.2
1.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
136
1274
1.68
1.09
16.1
12.3
mg/l
18.5
23.4
1.34
119
985
(3045414) Leukocytes [Presence] in Urine
10
52
1.99
1.09
1.3
1.7
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
37
277
1.44
1.08
1.3
1.2
u/ml
0.6
1.9
—
9
80
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
22
2.31
1.04
3.2
2.9
e9/l
4.1
5.5
—
5
22
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
5
22
2.31
1.04
2.8
1.2
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
13
76
1.78
1.02
1.3
1.3
—
47.9
—
0
6
(3013139) Helicobacter pylori Ag [Presence] in Stool
14
84
1.73
1.02
1.1
1.3
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
7
35
2.05
1.01
1.3
1.2
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
5
23
2.21
0.99
3.6
3.7
%
62.4
62.7
—
5
23
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
27
2.27
0.94
1.0
1.3
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
6
28
2.19
0.92
2.0
2.5
mmol/l
25.9
25.2
—
6
23
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
6
28
2.19
0.92
1.0
1.8
g/l
5.0
3.8
—
6
28
(3011397) Hemoglobin [Presence] in Urine by Test strip
36
277
1.39
0.91
3.3
3.3
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
29
2.11
0.90
1.0
1.3
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
8
42
1.95
0.90
1.1
1.0
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
8
42
1.95
0.90
1.1
1.0
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
73
628
1.31
0.89
3.5
3.5
estimate
0.0
0.0
—
10
119
(42529406) Shigella sp [Presence] in Stool by Culture
8
43
1.91
0.89
1.1
1.1
—
—
—
0
0
(40768443) Skin Pathology biopsy report
8
43
1.91
0.89
1.3
1.2
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
12
72
1.72
0.88
3.2
1.5
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
14
88
1.65
0.88
2.4
2.4
—
19.7
—
0
5
(3019150) Specific gravity of Urine by Refractometry
34
262
1.38
0.85
3.4
3.6
kg/l
1.0
1.0
—
9
44
(3000330) Specific gravity of Urine by Test strip
11
65
1.75
0.85
1.7
3.5
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
140
1335
1.67
0.84
18.1
14.1
umol/l
71.8
71.1
0.20
140
1335
(3019225) pH of Specimen
14
89
1.63
0.84
2.9
3.5
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
72
622
1.30
0.84
4.9
5.0
estimate
0.0
0.0
—
10
123
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
124
1156
1.41
0.83
6.9
5.0
mmol/mol
39.5
38.8
0.36
117
1086
(3023511) Choriogonadotropin [Units/volume] in Urine
6
32
1.91
0.82
2.2
1.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
35
273
1.37
0.81
1.4
1.4
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
26
193
1.42
0.80
1.7
1.6
nmol/l
1271.5
1309.9
0.09
20
147
(3013650) Neutrophils [#/volume] in Blood by Automated count
81
714
1.29
0.80
10.4
9.6
e9/l
3.9
4.0
0.41
75
628
(3049717) Cytology report of Urine Cyto stain
6
34
1.80
0.77
2.3
1.7
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
5
24
2.12
0.75
1.4
1.2
—
—
—
0
0
(1002224) Polysomnography panel
9
55
1.68
0.75
1.2
1.1
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
22
161
1.43
0.73
1.1
1.2
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
5
25
2.03
0.73
28.0
1.9
—
—
—
0
0
(3013290) Carbon dioxide [Partial pressure] in Blood
5
26
1.95
0.71
2.8
3.0
kpa
4.9
5.3
—
5
26
(3027315) Oxygen [Partial pressure] in Blood
5
26
1.95
0.71
2.8
3.0
kpa
10.5
8.5
—
5
26
(3003327) Ova and parasites identified in Stool by Light microscopy
7
41
1.74
0.71
2.1
1.5
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
44
363
1.30
0.71
2.4
2.8
e6/l
20.3
73.5
1.44
34
269
(3000764) Benzodiazepines [Presence] in Urine
7
42
1.70
0.69
4.3
1.4
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
7
42
1.70
0.69
4.1
1.4
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
7
42
1.70
0.69
4.3
1.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
56
479
1.27
0.68
3.3
3.6
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
7
43
1.66
0.68
4.3
1.3
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
38
309
1.31
0.68
5.5
3.7
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
10
62
1.66
0.67
2.3
3.5
kpa
5.0
5.2
—
10
56
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
5
28
1.81
0.67
1.8
1.5
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
5
28
1.81
0.67
2.2
1.6
—
—
—
0
0
(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum
7
44
1.62
0.66
1.4
1.2
—
2.5
—
0
5
(40768804) Tissue Pathology biopsy report
59
510
1.26
0.65
2.4
1.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
44
367
1.28
0.65
3.2
2.7
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
5
29
1.75
0.64
1.0
1.8
—
—
—
0
0
(4035726)
16
113
1.47
0.64
1.3
1.4
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
8
50
1.63
0.62
1.4
1.4
—
—
—
0
0
(3034274) Bile acid [Moles/volume] in Serum --fasting
5
30
1.69
0.62
1.4
2.4
umol/l
3.6
4.2
—
5
23
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
37
304
1.29
0.61
3.3
3.0
ng/l
674.1
1146.3
0.81
32
254
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
11
72
1.57
0.61
1.1
1.0
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
57
495
1.24
0.60
3.1
2.7
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
6
35
1.74
0.58
1.2
1.1
—
4.2
—
0
6
(3021589) Normoblasts [#/volume] in Blood
64
565
1.23
0.57
13.3
8.5
e9/l
0.0
0.0
0.80
57
463
(3052851) Hemolysis interference index of Serum or Plasma
6
37
1.65
0.56
2.7
2.5
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
39
327
1.26
0.55
2.4
2.6
—
—
—
0
0
(3000991) Gas panel - Venous blood
11
74
1.52
0.55
5.0
7.0
—
—
—
0
0
(3022313) Gas panel - Capillary blood
6
38
1.60
0.55
1.7
3.8
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
12
83
1.48
0.53
2.8
2.5
g/l
66.8
68.4
0.54
12
77
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
23
181
1.32
0.52
2.0
2.5
e6/l
0.9
3.1
1.66
14
85
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
28
229
1.27
0.48
1.8
1.7
pmol/l
400.7
452.7
0.78
23
204
(3003694) ABO and Rh group [Type] in Blood
30
358
0.80
0.47
1.3
1.5
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
17
131
1.34
0.44
3.7
3.0
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
36
307
1.23
0.44
3.7
2.9
%
102.3
95.6
0.77
36
300
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
8
58
1.40
0.42
7.6
7.8
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
12
88
1.40
0.41
3.7
4.9
%
0.4
0.4
—
5
19
(40768795) Lymph node Pathology biopsy report
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
5
34
1.49
0.40
5.4
1.4
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3026782) Osmolality of Urine
28
235
1.24
0.40
2.3
2.5
mosm/kgh2o
526.0
554.3
0.22
23
205
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
9
66
1.39
0.39
6.4
4.6
mmol/l
24.9
25.0
—
9
66
(3021440) Promyelocytes/100 leukocytes in Blood
12
89
1.38
0.39
4.0
5.1
%
0.2
0.2
—
5
27
(40760892) CBC W Ordered Manual Differential panel - Blood
35
302
1.21
0.38
4.2
4.8
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
138
1342
1.33
0.38
14.9
11.5
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
17
135
1.29
0.37
39.1
22.3
—
1.1
—
0
14
(3023323) Follitropin [Units/volume] in Serum or Plasma
9
71
1.28
0.37
1.2
1.4
iu/l
36.1
27.4
—
9
66
(3036489) Thrombin time
6
41
1.48
0.36
1.2
1.6
s
21.0
20.8
—
6
34
(4010399)
11
82
1.37
0.35
1.2
1.3
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
13
100
1.33
0.35
3.8
4.7
%
0.8
1.0
—
5
33
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
6
44
1.38
0.35
1.5
2.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
20
164
1.25
0.35
1.9
2.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
23
192
1.23
0.34
2.0
2.4
e6/l
0.5
0.8
0.88
14
94
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
17
137
1.27
0.34
1.3
1.5
—
—
—
0
0
(3003338) MCHC [Mass/volume]
106
1107
0.86
0.33
21.6
15.9
g/l
331.5
331.9
0.20
106
1102
(3025159) Blasts/100 leukocytes in Blood
11
83
1.35
0.33
4.2
5.3
%
0.0
0.0
—
5
21
(3012544) pH of Venous blood
13
101
1.31
0.33
3.1
2.8
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
6
47
1.29
0.32
1.3
1.5
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
6
47
1.29
0.32
1.3
1.5
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
6
47
1.29
0.32
1.3
1.5
—
—
—
0
0
(3020891) Body temperature
6
47
1.29
0.32
5.2
4.3
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
6
47
1.29
0.32
1.3
1.5
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
52
1.36
0.31
1.9
2.9
%
0.9
1.3
—
7
52
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
33
289
1.18
0.31
1.7
1.6
mg/l
0.8
1.1
0.88
26
234
(3015171) Extractable nuclear Ab [Units/volume] in Serum
7
55
1.29
0.30
1.3
1.3
—
5.2
—
0
5
(3044640) Blood type and Crossmatch panel - Blood
42
379
1.15
0.28
2.1
2.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
13
106
1.25
0.24
3.5
3.4
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
5
38
1.33
0.23
5.4
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
35
316
1.14
0.23
8.8
6.7
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
5
40
1.26
0.22
1.2
1.4
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
40
1.26
0.22
1.2
1.2
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(44813793)
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
10
80
1.27
0.21
1.7
1.3
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
16.2
—
1831.0
—
0
13
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
9.3
—
973.8
—
0
13
(3007164) IgA [Mass/volume] in Serum or Plasma
27
242
1.14
0.20
1.9
1.3
g/l
2.0
2.3
0.59
17
150
(3029937) Albumin [Presence] in Urine by Test strip
36
330
1.12
0.19
3.5
3.5
estimate
0.0
0.0
—
9
122
(3044889) 12 lead EKG panel
89
856
1.10
0.18
3.8
3.5
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
59
1.20
0.18
1.4
1.3
—
—
—
0
0
(40761535) Cells panel - Urine sediment
11
91
1.23
0.18
3.0
3.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
69
1.17
0.17
1.1
1.3
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
62
589
1.09
0.16
3.8
3.8
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
11
92
1.21
0.16
1.4
1.6
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
36
334
1.10
0.15
2.6
2.7
e6/l
0.2
0.5
0.89
26
240
(3009542) Hematocrit [Volume Fraction] of Blood
120
1177
1.10
0.13
17.6
13.1
%
39.8
39.3
0.29
85
890
(3041096) Erythrocytes [Presence] in Urine by Automated
38
357
1.09
0.13
3.1
3.3
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
5
43
1.17
0.10
1.4
1.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
5
43
1.17
0.10
1.4
1.4
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
5
45
1.11
0.10
1.6
1.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
16
145
1.12
0.10
1.4
1.2
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
30
282
1.08
0.09
2.2
2.0
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
6
54
1.12
0.09
1.5
1.6
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
6
55
1.09
0.09
3.2
6.0
%
1.4
1.5
—
6
50
(3007930) Methemoglobin/Hemoglobin.total in Blood
6
55
1.09
0.09
3.2
6.1
%
1.0
0.9
—
6
50
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
6
58
1.04
0.08
1.0
2.3
mg/l
4.5
2.6
—
6
41
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
5
60
0.83
0.08
1.0
1.5
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
6
74
0.80
0.08
4.0
1.8
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
8
73
1.10
0.07
3.1
2.2
—
—
—
0
0
(3008152) Bicarbonate [Moles/volume] in Arterial blood
8
75
1.07
0.07
7.5
8.1
mmol/l
24.9
25.2
—
8
69
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
16
147
1.10
0.07
2.0
2.0
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
9
87
1.04
0.07
1.6
1.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
15
162
0.92
0.06
1.9
2.0
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
14
130
1.08
0.05
1.8
1.8
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
13
140
0.92
0.04
1.1
1.3
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
12
111
1.09
0.04
7.1
7.7
%
96.8
95.5
0.79
12
106
(3000492) Spirometry study
12
112
1.08
0.03
1.6
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
14
133
1.06
0.01
1.8
1.9
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
19
183
1.04
0.01
3.5
3.9
%
16.5
22.2
—
10
84
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
86
867
0.98
0.01
3.1
3.4
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
24
246
0.97
0.00
2.2
1.9
—
—
—
0
0
(3027801) Oxygen [Partial pressure] in Arterial blood
13
127
1.03
0.00
6.6
7.2
kpa
12.3
12.2
0.03
13
122
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
13
127
1.03
0.00
6.6
7.2
kpa
5.2
5.2
0.02
13
122
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
14
138
1.02
0.00
8.1
8.0
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
10
95
1.06
0.00
2.9
1.9
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
6
60
1.00
0.00
1.5
1.5
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
10.2
—
0
6
(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768793) Breast Pathology biopsy report
5
51
0.98
0.00
1.0
1.3
—
—
—
0
0
(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3034426) Prothrombin time (PT)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.8
—
156.6
—
0
5
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3045716) Anion gap in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
8.3
—
0
6
(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(4198724)
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
5
52
0.96
0.00
1.6
1.7
ug/l
0.6
1.7
—
5
47
(3002619) Bacteria identified in Specimen by Culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045683) HLA typing for celiac disease panel - Blood or Tissue
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3019060) Gas panel - Arterial blood
7
76
0.92
0.00
5.3
5.0
—
—
—
0
0
(3047189) Immunofixation for 24 hour Urine
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
13
130
1.00
0.00
3.5
2.9
ug/l
0.6
0.7
—
8
84
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3013293) Extractable nuclear Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
21.3
—
0
7
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
7
78
0.89
0.00
1.9
1.3
u/ml
231.3
191.4
—
7
73
(21491868) Cryoglobulin [Mass/volume] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001964) Herpes simplex virus Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
7
0.00
0.00
0.0
10.7
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
12.9
—
0
8
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(40757494) Bilirubin.total [Moles/volume] in Blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3000012) Reticulocyte production index
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761539) Cells [Type] in Urine sediment by Light microscopy
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_THYROIDITACU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_THYROIDITACU | 1.181 [0.92, 1.52] | 0.199 |
| Birth year | 0.999 [0.99, 1.01] | 0.739 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 742 females with E4_THYROIDITACU died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have E4_THYROIDITACU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.117% | No data |
| 5 | 0.776% | No data |
| 10 | 1.927% | No data |
| 15 | 3.803% | No data |
| 20 | 6.664% | No data |
Relationships between endpoints
↥Index endpoint: E4_THYROIDITACU – Acute thyroiditis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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