Risteys · N14_VULVOVAGINFINOTH

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — N77* Cause of death: ICD-10 — N77* 2 out of 7 registries used, show all original rules.	2422
4. Check minimum number of events None	2422
5. Include endpoints None	2422
6. Filter based on genotype QC (FinnGen only)	2422

	All	Female	Male
Number of individuals
Whole population	13884	13884	-
Only index persons	13459	13459	-
Unadjusted period prevalence (%)
Whole population	0.40	0.40	-
Only index persons	0.49	0.49	-
Median age at first event (years)
Whole population	-	30.72	-
Only index persons	-	30.83	-

	All	Female	Male
Number of individuals	2422	2422	-
Unadjusted period prevalence (%)	0.83	0.83	-
Median age at first event (years)	35.51	35.51	-

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
2132: Matched controls
21319

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

N77.1*B37.3

ICD-10 Finland

Candidiasis of vulva and vagina

69.6

323.0

865

207

N77.1

ICD-10 Finland

Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere

99.2

323.0

651

N77.1*A60.0

ICD-10 Finland

Vaginitis, vulvitis and vulvovaginitis in herpesviral [herpes simplex] infection

145.1

323.0

372

J02AC01

ATC

fluconazole; systemic

4.2

198.1

1561

8413

J05AB01

ATC

aciclovir; systemic

4.0

164.1

842

2959

N77.0*A60.0

ICD-10 Finland

Ulceration of vulva in herpesviral [herpes simplex] infection

83.5

144.7

162

A60.0

ICD-10 Finland

Herpesviral infection of genitalia and urogenital tract

13.6

138.5

249

205

N76.0

ICD-10 Finland

Acute vaginitis

5.8

134.1

421

865

Z11.3

ICD-10 Finland

Special screening examination for infections with a predominantly sexual mode of transmission

5.3

115.3

390

863

N77.8*L43.9

ICD-10 Finland

Vulvovaginal ulceration and inflammation caused by lichen ruber planus

594.1

115.1

113

J05AB11

ATC

valaciclovir; oral

3.9

109.1

518

1602

R10.3

ICD-10 Finland

Pain localized to other parts of lower abdomen

2.6

82.7

813

4062

LC2BE

NOMESCO Finland

Transvaginal ultrasound examination of uterus, parametria and lower abdomen

2.4

80.9

1074

6286

ULA02

NOMESCO Finland

Kolposcopy

3.0

73.4

490

1901

N71.0

ICD-10 Finland

Acute inflammatory disease of uterus

12.6

72.9

134

113

LFB00

NOMESCO Finland

Biopsy of vulva or perineum

7.8

70.9

170

233

N76.8

ICD-10 Finland

Other specified inflammation of vagina and vulva

15.5

70.5

118

N77.8

ICD-10 Finland

Vulvovaginal ulceration and inflammation in other diseases classified elsewhere

144.7

66.3

P01AB01

ATC

metronidazole; oral, rectal

2.2

65.9

1030

6300

B37.3

ICD-10 Finland

Candidiasis of vulva and vagina

7.6

58.7

143

200

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

2.1

53.1

938

5864

N77.0

ICD-10 Finland

Ulceration of vulva in infectious and parasitic diseases classified elsewhere

112.9

51.0

G01AA10

ATC

clindamycin; vaginal

2.3

48.6

561

2879

D01AC20

ATC

imidazoles/triazoles in combination with corticosteroids; topical

2.3

48.6

521

2581

J02AC02

ATC

itraconazole; systemic

2.4

48.5

491

2364

N76.1

ICD-10 Finland

Subacute and chronic vaginitis

6.3

43.7

120

199

N73.9

ICD-10 Finland

Female pelvic inflammatory disease, unspecified

12.6

42.5

J01DB01

ATC

cefalexin; oral

2.2

42.0

1795

15116

N76.3

ICD-10 Finland

Subacute and chronic vulvitis

24.8

41.1

XLD00

NOMESCO Finland

Sytologyspecimen from mouth of uterus

2.3

40.7

455

2275

R51.80

ICD-10 Finland

Headache

2.3

39.7

444

2216

D07AD01

ATC

clobetasol; topical

2.4

39.2

369

1687

L43.9

ICD-10 Finland

Lichen planus, unspecified

8.9

38.7

J01CA08

ATC

pivmecillinam; oral

1.8

38.3

1206

8903

J01EA01

ATC

trimethoprim; systemic

1.9

37.5

670

4058

D06BB03

ATC

aciclovir; topical

3.8

37.4

170

480

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

2.0

35.2

529

2980

J01MA02

ATC

ciprofloxacin; systemic

1.9

34.5

704

4446

A02BC02

ATC

pantoprazole; systemic

1.7

33.4

1246

9512

N70.0

ICD-10 Finland

Acute salpingitis and oophoritis

91.6

32.8

J01FA10

ATC

azithromycin; systemic

1.8

32.5

1425

11384

N76.2

ICD-10 Finland

Acute vulvitis

20.0

31.4

N771, B977

ICD-10 Finland

+∞

31.3

LC2AE

NOMESCO Finland

Ultrasound examination of uterus and parametria

2.1

31.0

400

2104

A56.0

ICD-10 Finland

Chlamydial infection of lower genitourinary tract

5.1

29.5

192

N30.0

ICD-10 Finland

Acute cystitis

2.1

28.9

369

1928

A63.0

ICD-10 Finland

Anogenital (venereal) warts

3.1

28.5

165

560

J01FF01

ATC

clindamycin; systemic

1.9

28.3

538

3270

H02AB06

ATC

prednisolone; systemic

1.7

28.2

895

6387

R30.0

ICD-10 Finland

Dysuria

4.1

27.9

112

283

J01AA02

ATC

doxycycline; systemic

1.7

27.3

1545

12911

A02BC05

ATC

esomeprazole; systemic

1.7

26.8

776

5370

A06AC01

ATC

ispaghula (psylla seeds); oral

1.9

26.8

454

2641

D07AC01

ATC

betamethasone; topical

1.7

26.5

674

4483

N03AX16

ATC

pregabalin; oral

1.9

26.5

430

2463

LEB00

NOMESCO Finland

Biopsy of vagina

5.4

26.1

153

N02AX02

ATC

tramadol; systemic, rectal

1.7

26.1

707

4789

L30.9

ICD-10 Finland

Dermatitis, unspecified

2.0

26.0

393

2190

J06.9

ICD-10 Finland

Acute upper respiratory infection, unspecified

1.6

25.9

1175

9168

L43.8

ICD-10 Finland

Other lichen planus

7.5

25.7

N30.9

ICD-10 Finland

Cystitis, unspecified

2.9

25.6

165

600

N39.0

ICD-10 Finland

Urinary tract infection, site not specified

2.1

25.5

315

1612

UKC02

NOMESCO Finland

Cystoscopy

2.6

25.4

195

791

U01

ICPC

Dysuria/painful urination

2.4

25.3

223

974

L90.0

ICD-10 Finland

Lichen sclerosus et atrophicus

4.4

25.3

217

M79.6

ICD-10 Finland

Pain in limb

1.7

25.0

723

4978

GD1AA

NOMESCO Finland

Thorax X-ray examination

1.7

25.0

652

4353

N70.1

ICD-10 Finland

Chronic salpingitis and oophoritis

131.5

24.6

E0000UV

ATC

1.6

24.4

896

6571

R10.1

ICD-10 Finland

Pain localized to upper abdomen

1.9

24.1

382

2159

G03CA03

ATC

estradiol; nasal, systemic, rectal, transdermal, vaginal

1.6

23.9

849

6164

J01DA01

ATC

[U] cefalexin; systemic

1.6

23.8

1310

10635

R01AD09

ATC

mometasone; nasal

1.6

23.6

1064

8201

N02BE01

ATC

paracetamol; systemic, rectal

1.8

23.6

1753

15424

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

1.9

22.6

406

2395

R53

ICD-10 Finland

Malaise and fatigue

1.8

22.6

446

2716

N76.6

ICD-10 Finland

Ulceration of vulva

9.8

22.3

N05BA04

ATC

oxazepam; oral

1.7

21.9

528

3418

N94.1

ICD-10 Finland

Dyspareunia

4.3

21.9

195

N73.6

ICD-10 Finland

Female pelvic peritoneal adhesions

+∞

21.9

D06

ICPC

Abdominal pain localized other

2.3

21.6

222

1045

N03AX12

ATC

gabapentin; oral

2.0

21.5

290

1533

WZB00

NOMESCO Finland

Telephone receipt or other advice

1.6

21.4

689

4832

M01AE02

ATC

naproxen; oral, rectal

1.6

21.2

1239

10062

S01XA20

ATC

artificial tears and other indifferent preparations; ophthalmic

1.6

20.8

739

5307

X90

ICPC

Genital herpes female

11.7

20.7

SPAT1262

SPAT

Handing over of treatment supplies

2.0

20.7

273

1432

N06AX11

ATC

mirtazapine; oral

1.6

20.6

637

4411

Z01.4

ICD-10 Finland

Gynaecological examination (general)(routine)

1.7

20.6

551

3666

J01CR02

ATC

amoxicillin and beta-lactamase inhibitor; systemic

1.5

20.5

1123

8945

U02

ICPC

Urinary frequency/urgency

1.9

20.5

318

1775

Z2221

NOMESCO Finland

Medical doctor

1.6

20.3

630

4360

UJF32

NOMESCO Finland

Coloscopy

1.8

20.2

392

2365

A02BC03

ATC

lansoprazole; oral

1.7

20.1

498

3237

WX408

NOMESCO Finland

General anesthesy, balanced

1.7

20.0

489

3167

J01MA12

ATC

levofloxacin; systemic

2.0

19.8

277

1484

R87.6

ICD-10 Finland

Abnormal findings in specimens from female genital organs, abnormal cytological findings

1.9

19.7

335

1930

D07AB02

ATC

hydrocortisone butyrate; topical

1.6

19.6

587

4022

R06.0

ICD-10 Finland

Dyspnoea

1.8

19.5

413

2558

XKD00

NOMESCO Finland

Uroflowmetry

3.3

19.5

307

N05CF01

ATC

zopiclone; oral

1.7

19.2

531

3556

M03BX02

ATC

tizanidine; oral

1.5

19.2

1291

10704

N30

ICD-10 Finland

Cystitis

2.1

18.9

224

1121

UJF30

NOMESCO Finland

Ileoscopy through colon

2.2

18.8

195

921

D06BB04

ATC

podophyllotoxin; topical

2.3

18.8

184

844

A10AE04

ATC

insulin glargine; parenteral

2.5

18.8

151

627

L29.2

ICD-10 Finland

Pruritus vulvae

4.1

18.8

181

G01AF05

ATC

econazole; vaginal

2.0

18.7

240

1244

Z71.2

ICD-10 Finland

Person consulting for explanation of investigation findings

1.7

18.6

514

3436

Z01.8

ICD-10 Finland

Other specified special examinations

1.7

18.6

419

2640

R21

ICPC

Throat symptom/complaint

1.6

18.5

597

4159

R01AD12

ATC

fluticasone furoate; nasal

1.6

18.5

749

5519

WX404

NOMESCO Finland

Intravenous generell anesthesy

1.7

18.4

441

2832

N83.2

ICD-10 Finland

Other and unspecified ovarian cysts

1.9

18.3

286

1597

G44.2

ICD-10 Finland

Tension-type headache

1.8

18.2

340

2020

K30

ICD-10 Finland

Functional dyspepsia

2.0

18.2

232

1200

N06AB04

ATC

citalopram; systemic

1.7

18.1

450

2918

N10

ICD-10 Finland

Acute tubulo-interstitial nephritis

2.1

18.1

223

1137

R52.9

ICD-10 Finland

Pain, unspecified

2.3

18.0

179

827

R06AE07

ATC

cetirizine; oral

1.5

17.7

1013

8039

R03AC02

ATC

salbutamol; inhalant

1.5

17.7

1120

9087

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

1.9

17.6

274

1526

Z03.9

ICD-10 Finland

Observation for suspected disease or condition, unspecified

1.8

17.6

357

2178

X72

ICPC

Genital candidiasis female

4.3

17.4

151

N72

ICD-10 Finland

Inflammatory disease of cervix uteri

24.2

17.3

R42

ICD-10 Finland

Dizziness and giddiness

1.8

17.3

362

2229

E000006

ATC

2.3

17.1

164

746

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

1.5

17.1

864

6659

F32.9

ICD-10 Finland

Depressive episode, unspecified

1.8

17.0

326

1948

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

2.1

16.9

201

1006

H04.10

ICD-10 Finland

Dry eye syndrome

2.1

16.9

212

1087

M54.5

ICD-10 Finland

Low back pain

1.5

16.5

667

4880

K08.80

ICD-10 Finland

Toothache NOS

2.0

16.5

213

1105

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

1.9

16.4

264

1486

C05AA08

ATC

fluocortolone; rectal, topical

1.9

16.4

260

1455

A07AA02

ATC

nystatin; oral

2.7

16.4

113

431

R07.4

ICD-10 Finland

Chest pain, unspecified

1.7

16.3

375

2373

LCA06

NOMESCO Finland

Biopsy of endometrium

1.8

16.2

314

1883

AA1AD

NOMESCO Finland

CT of head and brain

1.8

16.1

305

1816

N39.4

ICD-10 Finland

Other specified urinary incontinence

2.3

15.8

150

679

M54.9

ICD-10 Finland

Dorsalgia, unspecified

1.9

15.7

244

1356

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

1.7

15.6

336

2078

R01AD08

ATC

fluticasone; nasal

1.5

15.5

638

4676

F41.9

ICD-10 Finland

Anxiety disorder, unspecified

1.8

15.4

274

1596

J01.0

ICD-10 Finland

Acute maxillary sinusitis

1.5

15.4

573

4104

ZXD10

NOMESCO Finland

Scheduled procedure

1.5

15.3

702

5264

S18

ICPC

Laceration/cut

1.5

15.3

649

4784

XQ800

NOMESCO Finland

Prick test

2.0

15.2

215

1152

U71

ICPC

Cystitis/urinary infection other

2.2

15.1

155

729

L17

ICPC

Foot/toe symptom/complaint

1.6

15.0

464

3170

XF400

NOMESCO Finland

ECG with 12 standard connections

2.0

14.9

211

1132

M03BC01

ATC

orphenadrine (citrate); systemic

1.6

14.9

509

3565

N01

ICPC

Headache

1.7

14.8

308

1887

R06AX27

ATC

desloratadine; oral

1.5

14.7

679

5089

R05

ICD-10 Finland

Cough

1.7

14.6

361

2322

M79.1

ICD-10 Finland

Myalgia

1.8

14.6

295

1788

215

Kela drug reimbursment

Diabetes, non-insulin-treated

1.8

14.3

286

1729

103

Kela drug reimbursment

Diabetes, insulin-treated

1.7

14.3

292

1777

M01AB05

ATC

diclofenac; systemic, rectal

1.4

14.2

1264

10750

ZXE00

NOMESCO Finland

One hour or less

1.5

14.2

800

6237

Z3231

NOMESCO Finland

Registered nurse

1.6

14.2

474

3295

K13.74

ICD-10 Finland

Lichen rubs planus in the mouth

4.7

14.1

101

Z03.8

ICD-10 Finland

Observation for other suspected diseases and conditions

2.8

14.1

333

R33

ICD-10 Finland

Retention of urine

3.3

14.0

211

M25.5

ICD-10 Finland

Pain in joint

1.5

13.9

578

4226

TLC00

NOMESCO Finland

Insertion of intrauterine device

1.9

13.8

227

1285

T78.4

ICD-10 Finland

Allergy, unspecified

2.3

13.8

136

626

R50.9

ICD-10 Finland

Fever, unspecified

1.8

13.8

261

1548

J01FA09

ATC

clarithromycin; systemic

1.5

13.7

663

5000

X15

ICPC

Vaginal symptom/complaint other

2.2

13.7

138

644

F41.2

ICD-10 Finland

Mixed anxiety and depressive disorder

1.8

13.6

268

1610

G01AF04

ATC

miconazole; vaginal

2.2

13.6

137

640

N77.8*M35.2

ICD-10 Finland

Ulceration of vulva in Behçet's disease

+∞

13.6

R10.2

ICD-10 Finland

Pelvic and perineal pain

3.6

13.5

169

Z3226

NOMESCO Finland

Physiotherapist

1.7

13.5

321

2041

A10AB05

ATC

insulin aspart; parenteral (insulins and analog. for injection, fast-acting)

2.3

13.5

124

555

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

2.2

13.4

145

696

G43.9

ICD-10 Finland

Migraine, unspecified

1.9

13.4

195

1057

Z01.2

ICD-10 Finland

Dental examination

1.4

13.4

914

7367

WX002

NOMESCO Finland

Sedation and analgesia

1.7

13.3

301

1885

Z03.3

ICD-10 Finland

Observation for suspected nervous system disorder

2.4

13.3

114

491

J01MA06

ATC

norfloxacin; oral

1.7

13.3

270

1638

E000001

ATC

1.5

13.3

456

3184

N75.0

ICD-10 Finland

Cyst of Bartholin gland

13.9

13.2

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

1.8

13.2

236

1375

JN3BD

NOMESCO Finland

Extensive abdominal CT

2.0

13.2

170

881

S01GX01

ATC

cromoglicic acid; ophthalmic

1.5

13.2

504

3611

H02AB04

ATC

methylprednisolone; systemic

1.7

13.1

270

1646

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

1.5

12.9

479

3405

D07CA01

ATC

hydrocortisone and antibiotics; topical

1.7

12.9

273

1674

R11

ICD-10 Finland

Nausea and vomiting

2.0

12.9

170

889

A02BC01

ATC

omeprazole; systemic

1.5

12.9

468

3309

R74

ICPC

Upper respiratory infection acute

1.4

12.9

759

5938

Z09.0

ICD-10 Finland

Follow-up examination after surgery for other conditions

1.9

12.8

185

999

M01AH05

ATC

etoricoxib; oral

1.4

12.8

1098

9194

H02AB07

ATC

prednisone; oral

1.8

12.8

244

1454

X14

ICPC

Vaginal discharge

2.6

12.6

358

R01AD58

ATC

fluticasone, combinations; inhalant, nasal

1.5

12.6

519

3775

N90.8

ICD-10 Finland

Other specified noninflammatory disorders of vulva and perineum

4.3

12.5

110

N05CF02

ATC

zolpidem; oral

1.6

12.5

350

2319

M01AE03

ATC

ketoprofen; systemic, rectal

1.5

12.4

613

4624

R51

ICD-10 Finland

Headache

2.1

12.4

145

722

T81.0

ICD-10 Finland

Haemorrhage and haematoma complicating a procedure, not elsewhere classified

2.3

12.4

119

543

Z03.89

ICD-10 Finland

Observation for other suspected diseases and conditions

1.8

12.3

243

1458

D11

ICPC

Diarrhoea

1.7

12.3

275

1714

LFB20

NOMESCO Finland

Destruction of lesion of vulva or perineum

5.5

12.2

R07.3

ICD-10 Finland

Other chest pain

2.0

12.2

150

765

D06BB10

ATC

imiquimod; topical

2.3

12.1

109

482

KC1EE

NOMESCO Finland

Ultrasound measurement of residual urine

2.7

12.1

299

K21.9

ICD-10 Finland

Gastro-oesophageal reflux disease without oesophagitis

1.9

12.1

176

956

A02BA02

ATC

ranitidine; systemic

1.7

12.1

283

1790

A04

ICPC

Weakness/tiredness general

1.7

12.1

272

1702

D01

ICPC

Abdominal pain/cramps general

1.7

12.1

254

1556

R03DC03

ATC

montelukast; oral

1.6

12.0

355

2385

M03BC51

ATC

orphenadrine, combinations; systemic

1.5

12.0

568

4242

R13

ICD-10 Finland

Dysphagia

2.4

12.0

417

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

2.2

12.0

123

577

R35

ICD-10 Finland

Polyuria

2.7

11.9

320

J45.9

ICD-10 Finland

Asthma, unspecified

1.6

11.9

319

2090

R23.8

ICD-10 Finland

Other and unspecified skin changes

1.7

11.9

264

1644

N92.1

ICD-10 Finland

Excessive and frequent menstruation with irregular cycle

1.9

11.9

176

961

WX110

NOMESCO Finland

Local anesthesy

1.4

11.9

1449

12827

DM1QA

NOMESCO Finland

Paranasal sinuses X-ray examination in one projection

2.4

11.9

102

442

O04.9

ICD-10 Finland

Medical abortion, complete or unspecified, without complication

1.6

11.8

297

1912

J01DA09

ATC

[U] cefadroxil; inhalant, oral

1.5

11.8

549

4085

N71.9

ICD-10 Finland

Inflammatory disease of uterus, unspecified

7.4

11.7

D07AB08

ATC

desonide; topical

1.8

11.7

223

1327

M54.8

ICD-10 Finland

Other dorsalgia

2.5

11.6

393

U05

ICPC

Urination problems other

2.9

11.6

236

G43.1

ICD-10 Finland

Migraine with aura [classical migraine]

1.8

11.6

196

1121

N06AB10

ATC

escitalopram; oral

1.5

11.6

492

3590

N06AX21

ATC

duloxetine; oral

1.7

11.6

230

1387

R06AE09

ATC

levocetirizine; oral

1.6

11.6

350

2364

M01AE01

ATC

ibuprofen; systemic, rectal

1.6

11.5

1923

18081

N06AA09

ATC

amitriptyline; systemic

1.9

11.5

163

875

6146A

ICD-9 Finland

Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female

+∞

11.5

JN3AA

NOMESCO Finland

Abdominal X-ray examination without contrast

2.9

11.4

233

N02AJ06

ATC

codeine and paracetamol; systemic

1.4

11.4

670

5212

N06AX16

ATC

venlafaxine; oral

1.6

11.3

328

2192

C01CA24

ATC

epinephrine; parenteral

1.9

11.3

156

831

S29

ICPC

Skin symptom/complaint other

1.6

11.3

292

1896

G04BD12

ATC

mirabegron; oral

2.1

11.3

121

582

ZXD05

NOMESCO Finland

Urgent procedure

1.4

11.3

635

4895

SPAT1263

SPAT

Sampling

1.4

11.2

847

6882

JAH01

NOMESCO Finland

Laparoscopy

2.2

11.1

110

508

L02

ICPC

Back symptom/complaint

1.8

11.1

202

1180

J01FA06

ATC

roxithromycin; oral

1.4

11.1

768

6142

G04BD07

ATC

tolterodine; oral

2.7

11.1

280

N05AH04

ATC

quetiapine; oral

1.6

11.0

346

2358

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

1.4

11.0

647

5026

F33.10

ICD-10 Finland

Recurrent depression, moderate episode without somatic syndrome

1.9

11.0

155

833

J03.9

ICD-10 Finland

Acute tonsillitis, unspecified

1.9

10.9

155

835

A99

ICPC

Disease/condition unspecnature/site

2.0

10.9

140

726

Z71.8

ICD-10 Finland

Other specified counselling

1.4

10.9

520

3883

R39.1

ICD-10 Finland

Other difficulties with micturition

4.5

10.8

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

1.5

10.8

486

3585

SAA01

NOMESCO Finland

Simple examination of mouth

1.4

10.7

1535

13818

X59

ICD-10 Finland

Exposure to unspecified factor

1.6

10.7

302

2004

E11.9

ICD-10 Finland

Type 2 diabetes mellitus, without complications

1.7

10.6

216

1311

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

1.8

10.6

173

980

A06AD11

ATC

lactulose; oral

1.8

10.6

169

950

N06AB06

ATC

sertraline; oral

1.6

10.5

257

1643

D09

ICPC

Nausea

2.0

10.5

126

634

K59.0

ICD-10 Finland

Constipation

2.3

10.5

411

Z76.9

ICD-10 Finland

Person encountering health services in unspecified circumstances

2.0

10.4

141

746

P01

ICPC

Feeling anxious/nervous/tense

1.6

10.4

325

2206

61207

ICD-8 Finland

Acute salpingitis and oophoritis, suspecta

+∞

10.4

M75.1

ICD-10 Finland

Rotator cuff syndrome

1.5

10.4

340

2335

LCH13

NOMESCO Finland

Vacuum aspiration from uterus after medically induced abortion

2.8

10.3

237

N80.3

ICD-10 Finland

Endometriosis of pelvic peritoneum

2.3

10.3

407

SPAT1254

SPAT

Administration of medicine

1.7

10.3

239

1507

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

1.9

10.3

153

836

XLA10

NOMESCO Finland

2.1

10.3

121

607

NA1EA

NOMESCO Finland

Cervical spine X-ray examination with flexion

4.3

10.3

K58.0

ICD-10 Finland

Irritable bowel syndrome with diarrhoea

1.9

10.2

139

737

R07.0

ICD-10 Finland

Pain in throat

1.9

10.2

154

848

A01AB09

ATC

miconazole; local oral

1.9

10.1

152

834

B97.7

ICD-10 Finland

Papillomavirus as the cause of diseases classified to other chapters

11.3

10.0

XF600

NOMESCO Finland

Bloodpressure measurement

2.2

10.0

440

A10AC01

ATC

insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)

2.0

10.0

128

663

M02AA07

ATC

piroxicam; topical

1.4

10.0

546

4166

WYA05

NOMESCO Finland

Emergency visit or other similar visit involving procedures

1.3

10.0

996

8410

J01CA04

ATC

amoxicillin; systemic

1.5

10.0

1759

16301

G01AF01

ATC

metronidazole; vaginal

1.7

10.0

215

1324

H01.0

ICD-10 Finland

Blepharitis

2.0

9.9

118

593

TKC20

NOMESCO Finland

Catheterisation of bladder

2.4

9.9

374

G04BD11

ATC

fesoterodine; oral

3.4

9.9

142

T89

ICPC

Diabetes insulin dependent

2.4

9.9

344

N89.5

ICD-10 Finland

Stricture and atresia of vagina

16.8

9.9

B00.9

ICD-10 Finland

Herpesviral infection, unspecified

7.0

9.8

A10BK01

ATC

dapagliflozin; oral

2.9

9.8

205

L43.0

ICD-10 Finland

Hypertrophic lichen planus

9.6

9.8

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

1.4

9.8

488

3664

G04CA02

ATC

tamsulosin; oral

3.2

9.7

155

N95.0

ICD-10 Finland

Postmenopausal bleeding

1.9

9.7

137

735

K64.9

ICD-10 Finland

Haemorrhoids, unspecified

3.0

9.7

193

KH1AE

NOMESCO Finland

Urinary tract ultrasound examination

2.6

9.7

278

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

1.7

9.7

209

1289

N77

ICD-10 Finland

Vulvovaginal ulceration and inflammation in diseases classified elsewhere

55.2

9.6

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

2.2

9.6

462

R4110

NOMESCO Finland

Physiotherapy

1.5

9.6

415

3024

N03AE01

ATC

clonazepam; systemic

2.1

9.6

102

487

T90

ICPC

Diabetes non-insulin dependent

1.6

9.6

228

1445

A46

ICD-10 Finland

Erysipelas

1.9

9.6

142

778

SPAT1310

SPAT

Counselling related to known health issue

1.4

9.6

620

4873

L01

ICPC

Neck symptom/complaint

1.6

9.6

284

1904

J05AB09

ATC

famciclovir; oral

6.4

9.5

ZXE10

NOMESCO Finland

More than one and less than three hours

1.4

9.5

596

4654

E10.9

ICD-10 Finland

Type 1 diabetes mellitus, Without complications

2.2

9.5

436

WYA30

NOMESCO Finland

Preparations for expected poor cooperation

1.8

9.5

170

990

M54.2

ICD-10 Finland

Cervicalgia

1.9

9.5

143

788

G43.0

ICD-10 Finland

Migraine without aura [common migraine]

1.7

9.5

179

1063

A02BC04

ATC

rabeprazole; oral

1.8

9.4

156

887

ZXC10

NOMESCO Finland

Use of laser

3.3

9.4

137

N76.4

ICD-10 Finland

Abscess of vulva

7.6

9.4

6140A

ICD-9 Finland

Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Acute salpingitis and oophoritis[S-O-ITIS ACUTA]

+∞

9.4

A10BA02

ATC

metformin; oral

1.5

9.4

295

2006

M53.1

ICD-10 Finland

Cervicobrachial syndrome

1.6

9.4

228

1452

F43.0

ICD-10 Finland

Acute stress reaction

1.9

9.4

136

738

A10AE05

ATC

insulin detemir; parenteral

2.2

9.4

421

N02CC01

ATC

sumatriptan; nasal, systemic, rectal

1.5

9.3

390

2821

Z2445

NOMESCO Finland

Psychologist

2.2

9.3

447

R06AX22

ATC

ebastine; oral

1.5

9.3

387

2802

A01

ICPC

Pain general/multiple sites

1.9

9.3

141

777

K59.09

ICD-10 Finland

Constipation, unspecified

2.3

9.3

350

R22.9

ICD-10 Finland

Localized swelling, mass and lump, unspecified

1.8

9.2

147

826

LX1AE

NOMESCO Finland

Gynecological ultrasound examination as part of clinical examination

1.5

9.2

316

2193

N75.1

ICD-10 Finland

Abscess of Bartholin gland

7.3

9.2

N06AB03

ATC

fluoxetine; oral

1.6

9.2

254

1674

R06.4

ICD-10 Finland

Hyperventilation

3.3

9.2

140

ZXE20

NOMESCO Finland

More than three and less than five hours

1.7

9.2

183

1103

Z03

ICD-10 Finland

Medical observation and evaluation for suspected diseases and conditions, ruled out

1.8

9.2

155

887

F51.0

ICD-10 Finland

Nonorganic insomnia

1.5

9.2

301

2067

X23

ICPC

Fear sexually transm dis female

1.7

9.1

199

1231

C07AA05

ATC

propranolol; systemic

1.5

9.1

402

2942

L43

ICD-10 Finland

Lichen planus

5.1

9.1

J01AA07

ATC

tetracycline; systemic

1.5

9.1

359

2566

H29

ICPC

Ear symptom/complaint other

1.8

9.1

163

951

285

Kela drug reimbursment

Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)

2.5

9.1

290

B00.19

ICD-10 Finland

Other vesicular dermatitis caused by the herper simplex virus

5.6

9.0

C03CA01

ATC

furosemide; systemic

1.6

9.0

237

1539

R52.2

ICD-10 Finland

Other chronic pain

2.5

9.0

275

S02

ICPC

Pruritus

2.3

9.0

374

SFC01

NOMESCO Finland

Adjuvant procedure of filling therapy

1.4

9.0

464

3494

H10.3

ICD-10 Finland

Acute conjunctivitis, unspecified

1.9

9.0

129

696

XCK10

NOMESCO Finland

Photography of fundus of eye

1.9

8.9

127

686

A03FA01

ATC

metoclopramide; systemic, rectal

1.5

8.9

377

2733

D06BX01

ATC

metronidazole; topical

1.6

8.9

208

1314

O99.80

ICD-10 Finland

The fear of childbirth

1.7

8.8

180

1092

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

1.7

8.8

164

970

WX105

NOMESCO Finland

Surface analgesia on skin or mucosa

1.7

8.8

179

1086

SCA01

NOMESCO Finland

Simple analysis and advice of nutrition with regard to dentistry

1.4

8.7

650

5210

A10AB01

ATC

insulin (human); parenteral (insulins and analog. for injection, fast-acting)

2.3

8.7

334

R05

ICPC

Cough

1.4

8.7

433

3241

S21

ICPC

Skin texture symptom/complaint

1.6

8.7

212

1356

N05BA12

ATC

alprazolam; oral

1.7

8.7

183

1122

TLW99

NOMESCO Finland

Other minor surgical procedure in gynaecology

2.6

8.6

227

L03

ICPC

Low back symptom/complaint

1.4

8.6

473

3602

A01AB04

ATC

amphotericin B; local oral

2.4

8.6

309

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

1.4

8.6

402

2971

N05BA01

ATC

diazepam; systemic, rectal

1.6

8.6

199

1253

J30.10

ICD-10 Finland

Allergic rhinitis due to pollen

1.8

8.6

152

882

N39.3

ICD-10 Finland

Stress incontinence

1.8

8.6

136

763

GD1PA

NOMESCO Finland

X-ray examination of the lungs in one projection

2.1

8.6

452

K58.9

ICD-10 Finland

Irritable bowel syndrome without diarrhoea

2.3

8.6

341

R00.2

ICD-10 Finland

Palpitations

1.8

8.6

148

851

L43.3

ICD-10 Finland

Subacute (active) lichen planus

16.3

8.5

U07

ICPC

Urine symptom/complaint other

2.1

8.5

494

R10.0

ICD-10 Finland

Acute abdomen

2.5

8.5

267

M35.2

ICD-10 Finland

Behçet disease

20.1

8.5

R60.0

ICD-10 Finland

Localized oedema

1.8

8.5

138

780

TLC02

NOMESCO Finland

Simple extraction of IUD

1.9

8.5

125

684

F60.30

ICD-10 Finland

Emotionally unstable personality disorder, impulsive

2.6

8.4

242

XKC03

NOMESCO Finland

Water cystometry

2.8

8.4

184

F33.9

ICD-10 Finland

Recurrent depressive disorder, unspecified

2.0

8.4

111

583

D01AC03

ATC

econazole; topical

2.1

8.4

415

Z32.1

ICD-10 Finland

Pregnancy confirmed

1.5

8.4

344

2474

ZXE11

NOMESCO Finland

Procedure duration 60 to 89 minutes

1.8

8.4

134

753

M79.2

ICD-10 Finland

Neuralgia and neuritis, unspecified

3.0

8.4

156

F29

ICPC

Eye symptom/complaint other

1.8

8.3

150

878

62200

ICD-8 Finland

Infective diseases of uterus (except cervix), vagina and vulva, Endometritis acuta

+∞

8.3

RS221

NOMESCO Finland

3.7

8.3

M53.0

ICD-10 Finland

Cervicocranial syndrome

1.7

8.3

180

1111

X58

ICD-10 Finland

Exposure to other specified factors

1.6

8.3

225

1472

XKD06

NOMESCO Finland

Physiologic investigation of micturition

3.4

8.3

113

O20.9

ICD-10 Finland

Haemorrhage in early pregnancy, unspecified

2.0

8.3

485

Z2446

NOMESCO Finland

Social worker

1.9

8.3

126

698

G04BD08

ATC

solifenacin; oral

2.2

8.3

377

SXA20

NOMESCO Finland

Local application of medicine to mouth

1.8

8.3

149

872

A06AC51

ATC

ispaghula, combinations; systemic

2.1

8.3

412

K21.0

ICD-10 Finland

Gastro-oesophageal reflux disease with oesophagitis

1.8

8.2

138

786

L03.0

ICD-10 Finland

Cellulitis of finger and toe

1.9

8.2

123

674

N63

ICD-10 Finland

Unspecified lump in breast

1.7

8.2

154

914

SPAT1260

SPAT

Consultation of another employee

1.5

8.2

304

2145

ZXD31

NOMESCO Finland

Major difficulties in performing procedure

2.3

8.2

338

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

1.8

8.2

145

844

J01DC02

ATC

cefuroxime; systemic

1.9

8.2

123

680

B02AA02

ATC

tranexamic acid; systemic

1.5

8.1

349

2535

Z20.2

ICD-10 Finland

Contact with and exposure to infections with a predominantly sexual mode of transmission

2.3

8.1

331

N95.2

ICD-10 Finland

Postmenopausal atrophic vaginitis

2.0

8.1

102

525

LDA10

NOMESCO Finland

Curettage of cervix uteri

1.9

8.1

122

671

G03CA04

ATC

estriol; systemic, vaginal

2.2

8.1

399

N80.8

ICD-10 Finland

Other endometriosis

8.1

L02.8

ICD-10 Finland

Cutaneous abscess, furuncle and carbuncle of other sites

3.5

8.1

105

N75.8

ICD-10 Finland

Other diseases of Bartholin gland

17.2

8.1

TLE00

NOMESCO Finland

Dilatation of vagina

17.2

8.1

K12.00

ICD-10 Finland

Recurrent oral aphthae

3.6

8.0

H04AA01

ATC

glucagon; nasal, parenteral

2.4

8.0

274

K02.0

ICD-10 Finland

Caries limited to enamel

1.4

8.0

350

2549

O04.6

ICD-10 Finland

Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage

2.9

8.0

166

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

1.8

8.0

134

764

A10AB04

ATC

insulin lispro; parenteral (insulins and analog. for injection, fast-acting)

2.3

8.0

327

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

1.3

7.9

787

6566

L08

ICPC

Shoulder symptom/complaint

1.5

7.9

277

1926

H57.1

ICD-10 Finland

Ocular pain

2.3

7.9

318

L12

ICPC

Hand/finger symptom/complaint

1.5

7.9

257

1758

L15

ICPC

Knee symptom/complaint

1.4

7.9

338

2454

O47.0

ICD-10 Finland

False labour before 37 completed weeks of gestation

1.5

7.9

288

2024

7890A

ICD-9 Finland

Other symptoms involving abdomen and pelvis, Abdominal pain

2.0

7.9

488

ZXA10

NOMESCO Finland

Bilateral

1.5

7.9

275

1911

K60.1

ICD-10 Finland

Chronic anal fissure

2.8

7.9

175

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

1.8

7.8

142

834

E11.7

ICD-10 Finland

Type 2 diabetes mellitus, with multiple complications

3.2

7.8

119

M54.4

ICD-10 Finland

Lumbago with sciatica

1.5

7.8

292

2061

F32.10

ICD-10 Finland

Moderate depressive episode without somatic syndrome

1.6

7.8

209

1369

F15.1

ICD-10 Finland

Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use

9.4

7.8

R01BA52

ATC

pseudoephedrine, combinations; oral

1.3

7.8

571

4557

SHB00

NOMESCO Finland

Prepation and fitting of bite rail to mouth

1.5

7.7

275

1921

ZXA05

NOMESCO Finland

Left side

1.4

7.7

332

2412

SPAT1222

SPAT

Counselling/guidance promoting independent living

1.6

7.7

190

1216

K10.3

ICD-10 Finland

Alveolitis of jaws

1.9

7.7

103

544

K44.9

ICD-10 Finland

Diaphragmatic hernia without obstruction or gangrene

2.0

7.7

502

R01AD11

ATC

triamcinolone; nasal

1.6

7.7

177

1115

J01MA01

ATC

ofloxacin; systemic

1.8

7.6

120

672

N70.9

ICD-10 Finland

Salpingitis and oophoritis, unspecified

25.1

7.6

J32.0

ICD-10 Finland

Chronic maxillary sinusitis

1.7

7.6

156

950

SPAT1249

SPAT

Treatment-related counselling outside office

1.3

7.5

812

6844

R30.1

ICD-10 Finland

Vesical tenesmus

3.8

7.5

P76

ICPC

Depressive disorder

1.7

7.5

161

991

R30.9

ICD-10 Finland

Painful micturition, unspecified

6.2

7.5

LEB30

NOMESCO Finland

Destruction of lesion of vaginal mucosa

5.8

7.5

SPAT1324

SPAT

Screening procedure

0.7

7.5

317

4203

F43.1

ICD-10 Finland

Post-traumatic stress disorder

2.1

7.5

386

SPAT1305

SPAT

Counselling and guidance related to physical exercise

1.7

7.5

159

978

N06AG02

ATC

moclobemide; oral

2.2

7.5

340

P06

ICPC

Sleep disturbance

1.6

7.5

195

1264

N83.1

ICD-10 Finland

Corpus luteum cyst

2.9

7.5

149

M70.6

ICD-10 Finland

Trochanteric bursitis

1.6

7.5

198

1290

LFF00

NOMESCO Finland

Marsupialisation of Bartholin gland

80.4

7.4

SPAT1283

SPAT

Restricted health certificate

1.4

7.4

517

4085

N01BB02

ATC

lidocaine; parenteral

5.0

7.4

S00.0

ICD-10 Finland

Superficial injury of scalp

3.2

7.4

113

O24.0

ICD-10 Finland

Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent

2.3

7.4

270

N05BB01

ATC

hydroxyzine; systemic

1.8

7.4

125

716

WYA10

NOMESCO Finland

First aid or other corresponding healthcare contact

1.6

7.4

172

1084

A10BK03

ATC

empagliflozin; oral

2.0

7.4

419

LDA20

NOMESCO Finland

Biopsy of vaginal cervix

1.6

7.3

204

1344

A04AA01

ATC

ondansetron; systemic, rectal

1.9

7.3

108

590

SBA00

NOMESCO Finland

Microbiological examinations

2.8

7.3

159

H81.1

ICD-10 Finland

Benign paroxysmal vertigo

1.7

7.3

149

905

N03AX09

ATC

lamotrigine; oral

1.8

7.3

114

638

B00.1

ICD-10 Finland

Herpesviral vesicular dermatitis

4.2

7.3

K29.7

ICD-10 Finland

Gastritis, unspecified

2.6

7.3

201

J01

ICD-10 Finland

Acute sinusitis

1.8

7.3

123

708

H66.9

ICD-10 Finland

Otitis media, unspecified

1.7

7.3

138

820

WX320

NOMESCO Finland

Spinalanesthesy

1.4

7.2

354

2635

KCV04

NOMESCO Finland

Distension of bladder with fluid

4.3

7.2

R61.9

ICD-10 Finland

Hyperhidrosis, unspecified

4.3

7.2

R03AK07

ATC

formoterol and budesonide; inhalant

1.4

7.2

352

2620

ZXE06

NOMESCO Finland

Procedure duration 50 to 59 minutes

1.9

7.2

529

TPH04

NOMESCO Finland

Cathetrisation of vein

1.5

7.2

294

2113

N76

ICD-10 Finland

Other inflammation of vagina and vulva

3.0

7.2

127

R12

ICD-10 Finland

Heartburn

1.8

7.2

127

740

Z01.0

ICD-10 Finland

Examination of eyes and vision

1.5

7.2

247

1714

F43.22

ICD-10 Finland

Adaptation disorder with mixed anxiety and depression

1.9

7.2

107

591

WZC05

NOMESCO Finland

Specialty-specific consultation based on referral by dentist or doctor

1.9

7.1

518

D07BB04

ATC

hydrocortisone butyrate and antiseptics; topical

1.5

7.1

228

1554

JAL21

NOMESCO Finland

Laparoscopic excision or destruction of lesion of peritoneum

2.9

7.1

143

R4120

NOMESCO Finland

Occupational therapy

1.9

7.1

101

549

K59.00

ICD-10 Finland

Constipation caused by slow bowel passage (SCT)

3.5

7.1

M50.3

ICD-10 Finland

Other cervical disc degeneration

2.9

7.1

144

N06CA01

ATC

amitriptyline and psycholeptics; systemic

1.6

7.1

166

1049

LFB10

NOMESCO Finland

Excision of lesion of vulva or perineum

3.6

7.1

H92.0

ICD-10 Finland

Otalgia

1.9

7.1

106

585

A07EC02

ATC

mesalazine; oral, rectal

1.9

7.1

511

V49.9

ICD-10 Finland

Car occupant [any] injured in unspecified traffic accident

2.1

7.1

377

SPAT1312

SPAT

General health counselling

1.3

7.1

665

5490

J01EE02

ATC

sulfadiazine and trimethoprim; systemic

1.3

7.0

558

4493

ULC02

NOMESCO Finland

Hysteroscopy

1.8

7.0

113

637

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

1.5

7.0

217

1469

346

Kela drug reimbursment

Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)

2.3

7.0

257

N81.6

ICD-10 Finland

Rectocele

1.8

7.0

109

608

N30.1

ICD-10 Finland

Interstitial cystitis (chronic)

4.1

7.0

SPAT1301

SPAT

No procedures

1.3

7.0

530

4239

SPAT1250

SPAT

Comprehensive monitoring of chronic illness

1.5

7.0

283

2029

WZC10

NOMESCO Finland

Extensive specialist consultion with written report

2.0

6.9

450

J18.9

ICD-10 Finland

Pneumonia, unspecified

1.5

6.9

250

1752

X16

ICPC

Vulval symptom/complaint

2.5

6.9

202

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

1.7

6.9

130

771

ND2AA

NOMESCO Finland

Hand and fingers X-ray examination

1.7

6.9

145

887

M01AG02

ATC

tolfenamic acid; oral, rectal

1.4

6.9

356

2673

M54

ICD-10 Finland

Dorsalgia

1.5

6.9

223

1526

N92.6

ICD-10 Finland

Irregular menstruation, unspecified

1.6

6.9

180

1172

F11.25

ICD-10 Finland

Relationship caused by opiates continuously used

8.3

6.8

N76.5

ICD-10 Finland

Ulceration of vagina

8.3

6.8

S06.0

ICD-10 Finland

Concussion

1.6

6.8

168

1075

M79.7

ICD-10 Finland

Fibromyalgia

2.0

6.8

419

SPAT1104

SPAT

Monitoring of emergency patient

1.9

6.8

475

Z04.4

ICD-10 Finland

Examination and observation following alleged rape and seduction

4.2

6.8

E11.8

ICD-10 Finland

Type 2 diabetes mellitus, with unspecified complications

2.1

6.8

357

K52.9

ICD-10 Finland

Noninfective gastroenteritis and colitis, unspecified

2.2

6.8

310

J30.4

ICD-10 Finland

Allergic rhinitis, unspecified

2.0

6.7

398

N03AX11

ATC

topiramate; oral

2.1

6.7

324

P01AB02

ATC

tinidazole; oral, rectal

2.4

6.7

230

M01AX01

ATC

nabumetone; oral

2.2

6.7

303

G01AF08

ATC

tioconazole; vaginal

2.5

6.7

200

8201

FHL

Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis

3.2

6.7

100

I84.2

ICD-10 Finland

Internal hemorrhoids without complication

1.8

6.7

103

575

J22

ICD-10 Finland

Unspecified acute lower respiratory infection

2.0

6.7

442

N64.5

ICD-10 Finland

Other signs and symptoms in breast

2.2

6.7

271

SPAT1212

SPAT

Extensive examination of musculoskeletal system

1.7

6.7

141

867

EMB10

NOMESCO Finland

Tonsillectomy

1.6

6.7

162

1036

K13.79

ICD-10 Finland

Change in the oral mucosa UNS

2.8

6.7

139

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

1.5

6.6

204

1380

K03.66

ICD-10 Finland

Tooth plaque

1.8

6.6

110

629

E10.3

ICD-10 Finland

Type 1 diabetes mellitus, With ophthalmic complications

2.1

6.6

318

G03DB01

ATC

dydrogesterone; oral

1.4

6.6

362

2742

H10

ICD-10 Finland

Conjunctivitis

1.7

6.6

134

812

M79.0

ICD-10 Finland

Rheumatism, unspecified

2.1

6.6

331

C10AA07

ATC

rosuvastatin; oral

1.5

6.6

239

1673

K57.3

ICD-10 Finland

Diverticular disease of large intestine without perforation or abscess

1.6

6.6

169

1093

A10BJ02

ATC

liraglutide; parenteral

2.9

6.6

133

L20.9

ICD-10 Finland

Atopic dermatitis, unspecified

1.9

6.6

452

R2110

NOMESCO Finland

Giving the first information

1.6

6.5

159

1017

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

1.7

6.5

135

827

N80.9

ICD-10 Finland

Endometriosis, unspecified

2.2

6.5

280

D07AA02

ATC

hydrocortisone; topical

1.4

6.5

285

2078

N89

ICPC

Migraine

1.8

6.5

103

582

JN3AD

NOMESCO Finland

Abdominal CT examination

1.9

6.5

487

R05FB02

ATC

cough suppressants and expectorants

1.3

6.4

583

4776

XKD03

NOMESCO Finland

Urethral pressure profilometry

2.8

6.4

143

Z87.1

ICD-10 Finland

Personal history of diseases of the digestive system

1.3

6.4

767

6516

F32.2

ICD-10 Finland

Severe depressive episode without psychotic symptoms

1.6

6.4

147

925

M94.0

ICD-10 Finland

Chondrocostal junction syndrome [Tietze]

2.5

6.4

185

N77.1*B80

ICD-10 Finland

Vaginitis, vulvitis and vulvovaginitis in pinworm infection

70.0

6.4

SAA03

NOMESCO Finland

Extended examination of mouth

1.3

6.4

812

6947

R03AK06

ATC

salmeterol and fluticasone; inhalant

1.5

6.4

201

1364

D07AC13

ATC

mometasone; topical

1.3

6.4

502

4029

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

1.5

6.4

195

1316

XQ802

NOMESCO Finland

Epicutan test

1.8

6.4

546

L18

ICPC

Muscle pain

2.0

6.3

360

L50.8

ICD-10 Finland

Other urticaria

2.5

6.3

187

M01AC06

ATC

meloxicam; systemic, rectal

1.3

6.3

582

4773

F45.4

ICD-10 Finland

Persistent somatoform pain disorder

2.8

6.3

132

J35.0

ICD-10 Finland

Chronic tonsillitis

1.6

6.3

149

945

H66.0

ICD-10 Finland

Acute suppurative otitis media

1.6

6.3

146

923

NA1AD

NOMESCO Finland

Cervical spine CT examination

2.3

6.3

226

X01

ICPC

Genital pain female

3.0

6.3

111

2500B

ICD-9 Finland

Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]

2.3

6.3

227

P03

ICPC

Feeling depressed

1.5

6.3

239

1694

E10.00

ICD-10 Finland

Insulin-dependent diabetes diabetic hypoglycemic coma

3.3

6.3

H00.00

ICD-10 Finland

Hordeolum

2.0

6.3

391

J01CE02

ATC

phenoxymethylpenicillin; oral

1.3

6.3

1461

13451

K46

ICD-10 Finland

Unspecified abdominal hernia

+∞

6.3

K08.1

ICD-10 Finland

Loss of teeth due to accident, extraction or local periodontal disease

1.7

6.3

117

695

R51.81

ICD-10 Finland

Facial pain NOS

2.4

6.2

201

Z70.8

ICD-10 Finland

Other sex counselling

4.8

6.2

N90.4

ICD-10 Finland

Leukoplakia of vulva

7.0

6.2

A03

ICPC

Fever

1.4

6.2

357

2730

TPH20

NOMESCO Finland

Insertion of central venous catheter through subclavian or brachiocephalic vein

2.7

6.2

141

SPAT1240

SPAT

Therapeutic discussion

1.4

6.2

269

1956

J45.1

ICD-10 Finland

Nonallergic asthma

1.7

6.2

113

668

I84.9

ICD-10 Finland

Unspecified hemorrhoids without complication

2.0

6.2

358

D01AC02

ATC

miconazole; topical

1.8

6.1

519

JHB30

NOMESCO Finland

Rubber band ligature of haemorrhoids or prolapse of mucosa

1.9

6.1

402

F60.9

ICD-10 Finland

Personality disorder, unspecified

2.6

6.1

160

S71

ICPC

Herpes simplex

4.2

6.1

D02

ICPC

Abdominal pain epigastric

1.7

6.1

109

641

IGY01

NOMESCO Finland

Accelerated psychiatric treatment contact

2.4

6.1

205

ZY010

NOMESCO Finland

Hospital outpatient

1.7

6.1

114

680

G43

ICD-10 Finland

Migraine

1.6

6.1

140

883

K59.1

ICD-10 Finland

Functional diarrhoea

1.9

6.1

437

SPAT1215

SPAT

Assessment of need for medical rehabilitation

1.9

6.1

423

O98.3

ICD-10 Finland

Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium

8.6

6.1

K62.5

ICD-10 Finland

Haemorrhage of anus and rectum

2.0

6.0

354

F19.1

ICD-10 Finland

Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use

4.9

6.0

N92.0

ICD-10 Finland

Excessive and frequent menstruation with regular cycle

1.4

6.0

243

1742

NAME	N14_VULVOVAGINFINOTH
CONTROL_EXCLUDE	N14_FEMALEGENINF
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N77
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N77
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
N14_VULVOVAGINFINOTH	1.303 [1.09, 1.56]	0.004
Birth year	0.996 [0.99, 1.0]	0.405

N-year risk	Females	Males
1	0.112%	No data
5	0.75%	No data
10	1.751%	No data
15	3.739%	No data
20	6.78%	No data

Vulvovaginal ulceration/inflammation in other diseases

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints