No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1622 |
4. Check minimum number of eventsNone |
1622 |
5. Include endpointsNone |
1622 |
6. Filter based on genotype QC (FinnGen only) |
1622 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Herpesviral keratitis and keratoconjunctivitis
based on the number of shared cases.
Similar with more cases:
- Keratitis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12217 | 6572 | 5592 |
| Only index persons | 11504 | 6258 | 5246 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.19 | 0.16 |
| Only index persons | 0.22 | 0.23 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 53.84 | 55.22 | 52.20 |
| Only index persons | 53.05 | 54.42 | 51.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1622 | 917 | 705 |
| Unadjusted period prevalence (%) | 0.31 | 0.31 | 0.31 |
| Median age at first event (years) | 55.80 | 53.67 | 58.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1456
- Matched controls
- 14558
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01AD03
ATC
aciclovir; ophthalmic
302.8
323.0
1136
168
J05AB01
ATC
aciclovir; systemic
10.5
323.0
876
1826
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
+∞
323.0
445
*
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
4503599627370496.0
323.0
1179
*
H16.0
ICD-10 Finland
Corneal ulcer
43.3
241.2
301
87
H16.9
ICD-10 Finland
Keratitis, unspecified
544.1
238.6
231
5
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
698.2
190.4
184
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
5.1
183.2
948
3888
B00.5
ICD-10 Finland
Herpesviral ocular disease
204.0
143.5
147
8
J05AB11
ATC
valaciclovir; oral
5.8
136.2
453
1054
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.3
94.9
698
3176
H04.10
ICD-10 Finland
Dry eye syndrome
5.4
87.0
290
639
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
364.0
70.2
70
*
H16.2
ICD-10 Finland
Keratoconjunctivitis
197.4
55.4
57
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
52.4
50
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
50.7
338
1317
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
48.8
50.5
61
13
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
5.5
49.5
156
312
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.6
48.9
243
759
H18.8
ICD-10 Finland
Other specified disorders of cornea
105.6
47.1
51
5
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
450.7
44.5
44
*
B00.10
ICD-10 Finland
Herpes simplex facialis
16.3
41.2
67
43
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.2
39.9
237
839
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
7.1
39.4
99
147
H22.0*B00.5
ICD-10 Finland
Herpesviral iridocyclitis
+∞
38.7
37
*
S01FA04
ATC
cyclopentolate; ophthalmic
22.9
35.4
51
23
S01ED51
ATC
timolol, combinations; ophthalmic
3.8
35.2
158
448
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
126.4
34.8
37
*
05405
ICD-8 Finland
Herpes simplex, Kerato-conjunctivitis herpetica
344.7
34.0
34
*
S01AX11
ATC
[U] ofloxacin; ophthalmic
5.6
33.9
102
192
F01
ICPC
Eye pain
7.0
32.7
83
125
H17.1
ICD-10 Finland
Other central corneal opacity
323.7
32.0
32
*
H13.1*B00.5
ICD-10 Finland
Herpesviral conjunctivitis
89.6
31.8
35
*
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
10.1
31.8
64
66
H57.1
ICD-10 Finland
Ocular pain
5.9
30.1
86
152
S01ED01
ATC
timolol; ophthalmic
5.3
30.0
95
190
D11AX14
ATC
[U] tacrolimus; topical
29.3
29.9
40
14
H15.1
ICD-10 Finland
Episcleritis
32.4
29.1
38
12
Z94.7
ICD-10 Finland
Corneal transplant status
152.9
28.7
30
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.0
27.6
116
309
H16.8
ICD-10 Finland
Other keratitis
+∞
27.2
26
*
S01GX01
ATC
cromoglicic acid; ophthalmic
2.2
26.8
325
1689
H17.8
ICD-10 Finland
Other corneal scars and opacities
275.8
26.8
27
*
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
9.5
26.6
55
60
XCK10
NOMESCO Finland
Photography of fundus of eye
2.8
26.3
181
697
L20.0
ICD-10 Finland
Besnier prurigo
3.5
26.2
128
388
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
265.0
25.8
26
*
CG2S4
NOMESCO Finland
Photography of cornea
137.4
25.7
27
*
H02AB06
ATC
prednisolone; systemic
1.8
24.8
692
4887
B02.3
ICD-10 Finland
Zoster ocular disease
28.1
24.5
33
12
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
24.5
425
2547
D07AA02
ATC
hydrocortisone; topical
2.4
24.1
225
1027
S01EC01
ATC
acetazolamide; systemic
6.7
24.1
62
96
H16.3
ICD-10 Finland
Interstitial and deep keratitis
+∞
24.0
23
*
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
+∞
24.0
23
*
F29
ICPC
Eye symptom/complaint other
3.0
23.5
144
513
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
15.6
23.3
38
25
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.9
23.0
147
540
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
5.7
22.7
66
120
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
45.7
22.4
27
6
CG2T4
NOMESCO Finland
Topography assessment of cornea
24.3
22.2
31
13
H18.1
ICD-10 Finland
Bullous keratopathy
+∞
21.9
21
*
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
223.1
21.6
22
*
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
3.5
21.6
106
322
J01DB01
ATC
cefalexin; oral
1.9
20.9
1164
9928
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
+∞
20.9
20
*
D06BB03
ATC
aciclovir; topical
3.4
20.7
104
322
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.4
20.5
102
314
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.5
20.3
167
709
D11AX15
ATC
[U] pimecrolimus; topical
58.3
19.9
23
*
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
202.5
19.6
20
*
H03.1
ICD-10 Finland
Involvement of eyelid in other infectious diseases classified elsewhere
34.8
18.9
24
7
D11AH01
ATC
tacrolimus; topical
10.0
18.7
37
38
E000002
ATC
NA
2.3
18.4
182
850
TCG10
NOMESCO Finland
Removal of sutures from cornea
27.1
17.8
24
9
S01FA02
ATC
scopolamine; ophthalmic
13.9
17.8
30
22
H18.6
ICD-10 Finland
Keratoconus
182.0
17.5
18
*
XCH00
NOMESCO Finland
Eye pressure measurement
3.6
17.1
78
224
E0000UV
ATC
NA
1.6
16.1
545
3912
H03.1*B02.3
ICD-10 Finland
Zoster blepharitis
16.9
16.1
25
15
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
48.0
16.0
19
*
E000001
ATC
NA
1.8
15.6
295
1780
H01.0
ICD-10 Finland
Blepharitis
2.9
14.9
95
347
H10
ICD-10 Finland
Conjunctivitis
2.8
14.8
95
349
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.5
14.8
123
527
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
6.2
14.7
39
64
H25.1
ICD-10 Finland
Senile nuclear cataract
1.7
14.2
326
2084
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
9.8
14.2
28
29
S01EA03
ATC
apraclonidine; ophthalmic
8.9
14.0
29
33
H26.4
ICD-10 Finland
After-cataract
2.3
13.9
135
624
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
141.2
13.5
14
*
H20.8
ICD-10 Finland
Other iridocyclitis
141.2
13.5
14
*
114
Kela drug reimbursment
Glaucoma
2.3
13.4
127
578
L04AD01
ATC
ciclosporin; systemic
5.5
13.3
39
73
R50.9
ICD-10 Finland
Fever, unspecified
1.9
13.3
196
1080
S01EE01
ATC
latanoprost; ophthalmic
2.6
13.3
95
375
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
5.4
13.2
39
74
R03AC02
ATC
salbutamol; inhalant
1.5
13.2
710
5615
H191, B023
ICD-10 Finland
NA
+∞
12.5
12
*
F02
ICPC
Red eye
3.0
12.5
72
248
D07AC01
ATC
betamethasone; topical
1.6
12.5
464
3360
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
12.4
239
1441
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
12.4
574
4370
D07AC13
ATC
mometasone; topical
1.6
12.0
390
2725
F03
ICPC
Eye discharge
2.5
12.0
96
402
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
11.7
372
2581
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
5.1
11.7
36
72
R06AE07
ATC
cetirizine; oral
1.5
11.7
578
4445
S01BC03
ATC
diclofenac; ophthalmic
4.3
11.7
42
99
S01BC05
ATC
ketorolac; ophthalmic
3.0
11.7
67
230
D07CC01
ATC
betamethasone and antibiotics; topical
1.9
11.6
184
1039
H26.2
ICD-10 Finland
Complicated cataract
6.5
11.6
29
45
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
11.2
11.5
21
19
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
11.5
548
4173
J01CA04
ATC
amoxicillin; systemic
1.5
11.3
1100
9724
A02BC02
ATC
pantoprazole; systemic
1.5
11.3
860
7213
WX140
NOMESCO Finland
Parabulbar anesthesy
3.0
11.3
66
230
L04AA01
ATC
[U] ciclosporin; systemic
5.0
11.3
35
71
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
11.3
91
383
J01MA14
ATC
moxifloxacin; systemic
2.1
11.2
131
659
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
11.2
153
817
S01XA18
ATC
ciclosporin; ophthalmic
17.2
11.2
17
10
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
11.1
132
666
H20
ICD-10 Finland
Iridocyclitis
43.6
10.9
13
*
S01EC04
ATC
brinzolamide; ophthalmic
3.1
10.9
60
202
H02AB07
ATC
prednisone; oral
1.8
10.8
197
1166
B02.9
ICD-10 Finland
Zoster without complication
2.4
10.7
91
396
H18.4
ICD-10 Finland
Corneal degeneration
60.4
10.6
12
*
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
60.4
10.6
12
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
10.5
666
5356
H15.0
ICD-10 Finland
Scleritis
110.7
10.4
11
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
10.4
10
*
H19.2*B30.0
ICD-10 Finland
Epidemic keratoconjunctivitis
+∞
10.4
10
*
H17.0
ICD-10 Finland
Adherent leukoma
+∞
10.4
10
*
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
10.4
10
*
J01DA01
ATC
[U] cefalexin; systemic
1.4
10.4
846
7132
E000007
ATC
NA
2.5
10.4
81
337
F73
ICPC
Eye infection/inflammation other
4.1
10.3
39
97
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
32.7
10.3
13
*
N02AX02
ATC
tramadol; systemic, rectal
1.5
10.3
551
4275
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
10.0
257
1682
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
10.0
368
2634
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.0
10.0
128
668
S01EX03
ATC
NA
4.1
10.0
37
91
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.0
9.8
38
97
D07AB08
ATC
desonide; topical
1.9
9.8
153
859
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
55.3
9.7
11
*
L04AX01
ATC
azathioprine; systemic
2.6
9.6
68
266
S01FA01
ATC
atropine; ophthalmic
11.4
9.6
17
15
H40.0
ICD-10 Finland
Glaucoma suspect
2.1
9.5
103
502
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
4.0
9.4
36
91
B00.11
ICD-10 Finland
Herpes simplex labialis
5.0
9.4
29
59
N02BE01
ATC
paracetamol; systemic, rectal
1.5
9.4
1175
10673
H22.0
ICD-10 Finland
Iridocyclitis in infectious and parasitic diseases classified elsewhere
+∞
9.4
9
*
CGF35
NOMESCO Finland
Repair of cornea using graft
+∞
9.4
9
*
E85.80
ICD-10 Finland
Meretoja sick
+∞
9.4
9
*
H3603, E103
ICD-10 Finland
NA
5.9
9.1
24
41
D11AH02
ATC
pimecrolimus; topical
9.1
9.0
18
20
C03CA01
ATC
furosemide; systemic
1.5
9.0
353
2549
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.5
9.0
40
116
L04AA06
ATC
mycophenolic acid; systemic
4.4
8.9
31
72
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
6.1
8.9
23
38
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
8.7
8.8
18
21
J01FF01
ATC
clindamycin; systemic
1.5
8.7
342
2469
R03BA02
ATC
budesonide; inhalant
1.6
8.7
222
1446
H16
ICD-10 Finland
Keratitis
50.3
8.7
10
*
H13.1
ICD-10 Finland
Conjunctivitis in infectious and parasitic diseases classified elsewhere
50.3
8.7
10
*
TQW80
NOMESCO Finland
Local dermatologic skincare
3.1
8.7
45
147
R03AC13
ATC
formoterol; inhalant
2.4
8.7
73
318
ZXA10
NOMESCO Finland
Bilateral
1.6
8.6
240
1597
L20
ICD-10 Finland
Atopic dermatitis
3.3
8.5
41
127
H10.4
ICD-10 Finland
Chronic conjunctivitis
6.4
8.5
21
33
D02AE01
ATC
carbamide; topical
2.1
8.5
93
454
127
Kela drug reimbursment
Transplant complication
4.4
8.4
29
67
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
8.4
171
1046
H18.2
ICD-10 Finland
Other corneal oedema
90.5
8.4
9
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.8
8.4
135
766
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
8.3
450
3463
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
+∞
8.3
8
*
H190, B005
ICD-10 Finland
NA
+∞
8.3
8
*
H10.5
ICD-10 Finland
Blepharoconjunctivitis
4.2
8.3
30
73
N03AX16
ATC
pregabalin; oral
1.5
8.3
296
2095
CD2S4
NOMESCO Finland
Photography of eye
6.9
8.1
19
28
UJF32
NOMESCO Finland
Coloscopy
1.5
8.0
310
2229
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
7.9
394
2977
E000006
ATC
NA
2.0
7.9
100
519
J01FA06
ATC
roxithromycin; oral
1.4
7.9
523
4170
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.8
306
2206
H10.2
ICD-10 Finland
Other acute conjunctivitis
5.1
7.7
23
46
H25.8
ICD-10 Finland
Other senile cataract
1.8
7.7
127
727
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
7.6
346
2570
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.0
7.6
100
530
B00.0
ICD-10 Finland
Eczema herpeticum
8.9
7.5
15
17
S01AA12
ATC
tobramycin; ophthalmic
10.1
7.5
14
14
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
7.5
278
1978
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
7.4
123
705
H02AB04
ATC
methylprednisolone; systemic
1.6
7.4
179
1149
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
7.4
106
576
CFD10
NOMESCO Finland
Repair of conjunctiva
80.4
7.4
8
*
B02.8
ICD-10 Finland
Zoster with other complications
7.7
7.4
16
21
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.4
400
3067
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
7.3
7
*
0544B
ICD-9 Finland
Herpes simplex, With ophthalmic complications[KERATITIS DENDRITICA, HERPETICA]
+∞
7.3
7
*
R42
ICD-10 Finland
Dizziness and giddiness
1.5
7.2
257
1808
S01EC54
ATC
brinzolamide, combinations; ophthalmic
5.2
7.2
21
41
N03AX12
ATC
gabapentin; oral
1.6
7.1
194
1283
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.3
7.1
34
106
B00.1
ICD-10 Finland
Herpesviral vesicular dermatitis
6.1
7.1
18
30
R03BA05
ATC
fluticasone; inhalant
1.5
7.0
230
1591
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.0
220
1506
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
7.0
150
932
H01
ICPC
Ear pain/earache
1.8
7.0
121
701
T89
ICPC
Diabetes insulin dependent
2.5
7.0
53
220
UDC00
NOMESCO Finland
Ear microscopy
1.9
7.0
93
495
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
7.0
212
1440
A10AA01
ATC
NA
2.8
6.9
41
148
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.9
6.9
26
67
N05BB01
ATC
hydroxyzine; systemic
2.0
6.9
82
419
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
6.8
107
601
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.2
6.8
33
104
R06AX13
ATC
loratadine; oral
1.6
6.8
186
1231
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.8
503
4064
H02AB09
ATC
hydrocortisone; systemic
3.1
6.8
34
110
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
9.4
6.8
13
14
H26.02
ICD-10 Finland
Presenil cataract
2.9
6.8
39
137
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.8
460
3662
A46
ICD-10 Finland
Erysipelas
1.6
6.7
170
1104
R51.80
ICD-10 Finland
Headache
1.6
6.6
178
1173
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.7
6.6
41
153
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
6.6
158
1010
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.6
6.6
27
75
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.3
6.6
59
267
R06AX27
ATC
desloratadine; oral
1.4
6.6
324
2439
E000003
ATC
NA
2.2
6.5
63
292
J15.8
ICD-10 Finland
Other bacterial pneumonia
6.9
6.5
15
22
D09AB01
ATC
zinc bandage without supplements; topical
3.2
6.5
31
97
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.6
6.5
43
166
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
6.4
49
204
R06AX22
ATC
ebastine; oral
1.5
6.4
202
1383
R06AE09
ATC
levocetirizine; oral
1.6
6.4
174
1150
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
6.3
191
1293
N02AA05
ATC
oxycodone; systemic
1.6
6.3
172
1135
R03AC03
ATC
terbutaline; inhalant
1.6
6.3
172
1135
F70
ICPC
Conjunctivitis infectious
3.0
6.3
33
111
A10AE04
ATC
insulin glargine; parenteral
1.7
6.3
120
723
D06BX01
ATC
metronidazole; topical
1.7
6.3
133
826
3604
FHL
Penetration of the cornea
+∞
6.3
6
*
H19.3
ICD-10 Finland
Keratitis and keratoconjunctivitis in other diseases classified elsewhere
+∞
6.3
6
*
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
+∞
6.3
6
*
XCK00
NOMESCO Finland
Perimetry
1.9
6.2
87
470
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
6.2
350
2691
A10AE05
ATC
insulin detemir; parenteral
2.0
6.2
72
364
XQ800
NOMESCO Finland
Prick test
1.9
6.1
88
481
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
7.7
6.1
13
17
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
7.7
6.1
13
17
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.7
6.1
38
143
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.2
6.1
58
271
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
8.6
6.1
12
14
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.7
6.0
39
147
H25.0
ICD-10 Finland
Senile incipient cataract
2.0
6.0
69
347
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
176
106
18.50
214.21
1.2
1.2
—
—
—
0
0
73
55
13.85
77.96
1.1
1.2
—
—
—
0
0
53
22
24.87
74.78
1.3
1.0
—
—
—
0
0
957
7617
1.63
19.56
11.2
8.8
4.3
4.1
e9/l
1.04
878
6666
1184
10179
1.60
15.44
9.5
7.4
80.6
78.2
u/l
0.62
1129
9565
730
5669
1.52
14.99
5.9
4.7
35.0
35.5
g/l
1.50
680
5260
1135
9709
1.56
14.66
5.4
3.9
13.2
12.3
mm/h
1.17
1061
8961
554
4125
1.52
13.48
3.1
2.5
53.3
57.4
u/l
2.61
519
3829
811
6528
1.48
13.48
8.0
6.7
1.2
1.2
mmol/l
0.16
695
5506
364
2470
1.61
13.34
1.6
1.4
2.6
2.5
g/l
0.62
239
1505
532
3972
1.51
12.59
2.2
2.2
161.8
240.2
u/l
1.44
495
3730
929
7767
1.46
12.18
5.9
4.8
6.7
6.7
mmol/l
0.03
876
7274
800
6560
1.43
11.28
4.5
3.6
0.0
0.0
estimate
0.80
161
1190
1016
8721
1.44
11.03
5.2
4.5
2354.4
2300.2
e6/l
0.01
22
125
789
6473
1.43
10.99
4.5
3.6
0.0
0.0
estimate
0.00
174
1214
836
6937
1.42
10.88
7.3
6.2
11.8
11.4
umol/l
0.29
802
6579
789
6494
1.42
10.67
6.1
4.8
0.0
0.0
estimate
0.50
172
1230
259
1711
1.61
10.38
3.0
2.5
21.7
23.3
%
1.06
225
1469
1431
13249
1.68
10.22
20.5
14.0
22.8
24.2
mg/l
0.91
1207
10448
400
2927
1.49
10.06
1.8
1.7
1.1
1.2
mg/l
0.18
302
2221
292
2015
1.55
9.66
3.0
2.4
12.4
13.2
umol/l
1.17
270
1860
270
1839
1.56
9.45
2.9
2.4
2.4
2.3
g/l
0.76
252
1704
307
2157
1.52
9.32
2.2
1.8
—
—
—
0
0
377
2779
1.46
9.01
3.6
2.5
5.2
6.0
e6/l
0.49
336
2451
26
68
3.87
8.97
3.4
2.1
—
—
—
0
0
137
796
1.79
8.83
1.9
1.2
1741.5
179.8
u/ml
1.29
124
729
692
5693
1.38
8.79
3.4
2.8
128.6
126.3
ug/l
0.10
648
5244
27
74
3.69
8.74
3.1
2.2
0.2
0.2
e9/l
0.03
22
68
433
3300
1.43
8.61
2.5
2.1
3.0
3.0
mg/l
0.10
392
2792
382
2850
1.45
8.52
1.4
1.2
2.7
1.5
u/ml
0.81
116
776
663
5442
1.37
8.44
2.4
2.2
76.2
76.9
nmol/l
0.28
617
4871
1136
10154
1.40
8.43
4.5
4.0
14.6
14.8
pmol/l
2.08
1050
9258
27
77
3.55
8.26
3.1
2.1
519.7
599.9
e6/l
0.27
22
69
441
3401
1.41
8.13
3.2
2.6
5582.0
6452.0
umol/l
0.15
378
2953
480
3761
1.39
8.04
3.1
3.0
1557.8
1374.3
ng/l
0.37
415
3199
711
5942
1.35
7.90
7.2
6.0
1.2
1.2
mmol/l
0.06
663
5376
25
70
3.61
7.86
1.2
1.2
—
—
—
0
0
652
5383
1.35
7.82
2.0
2.0
96.2
95.1
pmol/l
0.24
346
2801
184
1199
1.60
7.73
2.4
2.1
334.3
371.0
nmol/l
1.84
174
1096
149
926
1.67
7.56
1.8
1.6
—
—
—
0
0
39
148
2.68
7.42
1.1
1.1
—
—
—
0
0
611
5025
1.35
7.41
4.8
3.8
—
—
—
0
0
449
3524
1.38
7.34
5.0
3.9
0.0
0.0
estimate
1.08
167
1192
508
4076
1.36
7.20
4.6
4.0
9.7
9.1
mg/mmol
0.09
352
2567
25
75
3.37
7.12
3.4
2.1
11.3
13.9
%
0.61
16
36
611
5056
1.33
7.01
4.2
3.6
48.0
48.6
ng/l
0.01
423
3464
1311
12141
1.42
6.93
5.4
4.7
1.9
2.0
mu/l
0.55
1226
11111
510
4121
1.35
6.83
4.1
3.2
7.5
7.5
mmol/l
0.02
442
3457
56
262
2.18
6.78
3.8
2.5
16.1
16.1
%
0.01
25
136
54
249
2.21
6.77
4.4
3.3
4.3
4.3
e9/l
0.05
54
249
205
1415
1.51
6.67
3.1
2.6
1.8
1.8
%
0.08
187
1258
216
1510
1.50
6.61
2.5
2.2
155.6
123.3
ug/g
0.50
170
1198
531
4334
1.33
6.61
3.4
3.2
30.4
33.8
u/l
1.53
509
4120
206
1427
1.51
6.59
4.7
4.2
250.5
249.2
u/l
0.04
196
1351
161
1062
1.57
6.43
2.7
2.7
65.8
66.7
g/l
0.85
151
972
54
258
2.13
6.23
4.5
3.5
56.4
58.9
%
0.76
54
258
275
2044
1.42
6.09
2.2
2.0
29.7
29.7
s
0.01
269
1981
175
1192
1.52
6.06
4.9
3.5
2.4
1.9
mmol/l
0.79
135
950
364
2838
1.36
6.05
1.7
1.7
92258501.3
31290068.1
pmol/l
0.55
310
2365
52
248
2.13
6.03
7.5
6.0
311.6
843.8
iu/ml
0.52
13
38
450
3632
1.33
5.93
4.3
3.1
0.6
0.5
e6/l
0.16
350
2763
1441
13665
1.49
5.93
21.9
16.3
4.0
4.0
mmol/l
0.79
1409
13280
290
2190
1.39
5.85
1.6
1.5
—
—
—
0
0
294
2228
1.39
5.80
1.3
1.2
35.1
31.5
iu/ml
0.13
93
696
168
1150
1.51
5.69
2.2
2.4
6.7
7.3
ug/l
0.15
142
1020
281
2122
1.39
5.66
3.6
3.3
0.8
0.8
mmol/l
0.07
267
1983
231
1689
1.43
5.59
23.5
25.4
1.4
1.3
inr
0.26
51
226
1435
13628
1.46
5.54
21.7
16.2
139.4
139.6
mmol/l
2.88
1408
13268
17
47
3.64
5.49
1.7
1.6
—
—
—
0
0
928
8293
1.28
5.48
3.2
3.0
—
—
—
0
0
538
4502
1.29
5.35
3.7
3.5
2.3
2.4
mmol/l
0.82
479
3938
168
1166
1.49
5.33
8.9
7.4
11.3
9.7
mmol/l
1.78
161
1109
384
3072
1.33
5.31
1.6
1.5
20.7
20.7
nmol/l
0.02
355
2640
90
539
1.71
5.30
1.8
2.0
40.2
39.3
u/l
0.14
81
478
1476
14119
1.50
5.24
13.5
10.2
26.2
26.2
u/l
0.01
1436
13640
322
2527
1.34
5.05
4.1
3.7
636.3
439.8
ng/l
0.29
245
1951
116
763
1.56
4.73
3.1
3.4
4.5
4.5
pmol/l
0.17
107
673
57
309
1.88
4.70
1.9
1.6
—
—
—
0
0
61
341
1.82
4.58
3.6
3.0
25.0
25.0
mmol/l
0.05
53
292
223
1678
1.38
4.56
7.5
7.1
104.0
104.2
mmol/l
0.17
216
1636
1360
12887
1.34
4.53
4.7
4.5
6.0
5.9
mmol/l
1.43
1258
11747
152
1070
1.46
4.51
3.8
2.9
153.6
194.3
ng/l
1.02
135
976
32
142
2.28
4.49
2.2
1.6
—
—
—
0
0
274
2136
1.34
4.47
1.3
1.2
13.7
11.1
u/ml
0.19
98
827
44
225
1.98
4.33
2.0
1.7
—
—
—
0
0
38
184
2.09
4.33
2.2
1.5
—
—
—
0
0
170
1233
1.42
4.31
2.2
2.2
0.2
0.2
g/l
0.85
156
1153
309
2464
1.31
4.30
3.4
3.0
2.5
2.5
mmol/l
0.15
269
2163
64
371
1.75
4.28
3.3
2.2
2362.8
3278.5
u/l
0.24
24
165
200
1496
1.38
4.24
2.0
1.7
—
—
—
0
0
966
8809
1.24
4.24
3.7
3.1
52.7
49.0
u/l
0.59
923
8232
229
1751
1.36
4.24
7.3
5.5
1.0
1.0
mmol/l
0.30
210
1612
309
2471
1.31
4.21
1.7
1.8
1191.1
1204.2
nmol/l
0.08
236
1851
25
103
2.45
4.14
1.9
1.8
—
—
—
0
0
23
91
2.55
4.14
3.0
2.1
565.4
692.8
e6/l
—
8
38
1527
14798
1.54
4.12
28.6
20.6
6.8
6.8
e9/l
0.38
1497
14377
78
483
1.65
4.12
2.1
1.8
—
—
—
0
0
52
288
1.83
4.06
5.6
4.7
4.9
5.0
kpa
1.20
52
283
1526
14796
1.53
4.00
28.6
20.6
4.5
4.5
e12/l
1.31
1498
14373
199
1505
1.37
3.95
2.1
1.8
—
—
—
0
0
1525
14788
1.52
3.95
28.7
20.6
252.8
250.4
e9/l
0.69
1499
14411
1526
14801
1.52
3.93
28.8
20.7
134.1
135.2
g/l
2.12
1510
14580
53
301
1.79
3.83
2.0
1.7
—
—
—
0
0
120
834
1.47
3.83
3.7
3.7
5.2
5.2
kpa
0.03
112
779
147
1063
1.42
3.81
4.5
3.6
1.2
1.2
mmol/l
0.28
134
912
83
533
1.59
3.80
2.3
1.9
—
—
—
0
0
65
393
1.68
3.78
2.6
1.8
—
—
—
0
0
349
2879
1.27
3.71
4.5
4.0
1.0
1.0
kg/l
0.30
62
427
201
1538
1.35
3.71
7.3
7.7
1.4
1.2
mmol/l
0.41
157
1206
276
2217
1.30
3.62
3.4
2.8
1.2
1.3
e6/l
0.21
161
1279
40
212
1.91
3.60
2.0
1.5
—
—
—
0
0
72
455
1.61
3.55
2.9
2.4
10.6
10.4
g/l
0.13
65
393
112
787
1.45
3.41
3.6
3.7
1.9
1.8
mmol/l
0.12
84
592
1285
12204
1.25
3.38
6.8
5.7
41.3
39.9
mmol/mol
3.89
1196
11309
9
18
5.02
3.37
1.2
2.1
—
—
—
0
0
61
375
1.65
3.36
2.0
1.7
—
—
—
0
0
198
1537
1.33
3.33
7.4
7.7
5.1
5.1
kpa
0.26
191
1472
75
487
1.57
3.32
2.9
2.4
3.7
3.8
g/l
0.17
58
361
198
1538
1.33
3.31
7.4
7.7
11.6
12.1
kpa
0.96
191
1474
75
488
1.56
3.29
2.9
2.4
7.3
7.4
g/l
0.26
61
377
75
488
1.56
3.29
2.9
2.4
—
—
—
0
0
179
1372
1.34
3.28
4.7
3.3
—
—
—
0
0
69
443
1.58
3.21
2.8
3.0
—
—
—
0
0
1312
12518
1.25
3.14
18.1
13.0
80.8
80.9
ml/min/173m2
0.05
1132
10296
32
166
1.95
3.10
2.2
1.5
—
—
—
0
0
6
8
7.52
3.05
2.3
1.1
—
—
—
0
0
1167
11016
1.21
3.01
23.0
17.1
13.9
13.7
%
3.68
1144
10772
22
100
2.22
3.00
2.1
1.5
—
—
—
0
0
70
459
1.55
2.99
3.0
2.4
3.0
3.1
g/l
0.75
60
367
60
380
1.60
2.98
1.8
1.6
0.1
20.1
iu/ml
—
9
60
83
566
1.49
2.97
2.0
1.9
1.5
1.5
g/l
0.25
73
492
1369
13148
1.26
2.96
4.7
4.4
4.5
4.7
mmol/l
5.14
1278
12203
475
4144
1.21
2.93
4.9
4.9
2.1
2.7
ug/l
1.00
428
3709
380
3246
1.22
2.90
2.5
2.3
—
—
—
0
0
16
65
2.48
2.79
1.1
1.9
—
—
—
0
0
16
65
2.48
2.79
1.1
1.9
—
—
—
0
0
16
65
2.48
2.79
1.1
1.9
—
—
—
0
0
16
65
2.48
2.79
1.1
1.9
—
—
—
0
0
387
3325
1.22
2.78
4.4
4.2
23.7
21.4
%
1.70
161
1591
159
1230
1.32
2.76
3.4
2.4
36.9
81.2
u/l
0.59
133
1052
188
1491
1.30
2.73
3.7
2.7
12.1
8.0
umol/l
0.83
169
1297
84
1182
0.69
2.72
1.7
1.7
—
—
—
0
0
25
125
2.02
2.71
2.3
2.0
28.7
8.5
umol/l
0.65
18
88
23
112
2.07
2.67
2.8
2.3
834.5
624.0
ml
2.48
13
73
12
43
2.80
2.65
1.5
1.1
31.3
35.0
nmol/l
0.16
12
33
7
15
4.68
2.60
2.1
2.3
—
—
—
0
0
55
354
1.57
2.59
2.1
1.7
37.9
39.9
nmol/l
0.24
55
338
16
68
2.37
2.56
1.2
1.5
1.1
1.2
nmol/l
0.18
11
54
1387
13390
1.25
2.54
5.3
4.8
2.6
2.8
mmol/l
6.28
1283
12350
694
6324
1.17
2.51
4.5
4.0
—
—
—
0
0
50
318
1.59
2.48
1.2
1.1
—
—
—
0
0
35
203
1.74
2.46
1.2
1.1
—
—
—
0
0
403
3516
1.19
2.44
1.7
1.7
1.4
1.4
mmol/l
0.76
337
2960
18
83
2.18
2.41
1.3
1.4
16.2
14.2
u/l
0.36
18
78
9
27
3.35
2.39
1.4
1.0
—
—
—
0
0
45
282
1.61
2.38
1.6
1.4
—
—
—
0
0
1354
13058
1.22
2.38
4.7
4.3
1.4
1.5
mmol/l
0.57
1261
12042
150
1178
1.30
2.37
6.5
7.2
1.2
1.4
mmol/l
2.34
145
1129
43
267
1.63
2.36
1.7
1.6
—
—
—
0
0
22
111
2.00
2.36
1.3
1.5
19.1
30.8
%
1.01
14
67
29
161
1.82
2.36
1.2
2.0
—
1666.7
—
0
6
114
864
1.34
2.31
1.2
1.2
99.5
142.0
iu/ml
0.72
39
343
169
1353
1.28
2.30
3.5
4.3
5.9
21.3
ug/l
1.52
144
1115
10
35
2.87
2.30
1.1
1.2
—
—
—
0
0
14
59
2.38
2.29
1.5
2.6
904.6
1456.1
u/ml
0.52
14
59
6
13
4.63
2.27
1.7
1.3
54.7
48.1
umol/l
—
6
13
30
171
1.77
2.25
4.0
2.6
105.6
105.3
mmol/l
0.13
30
171
30
171
1.77
2.25
4.0
2.6
4.1
4.1
mmol/l
0.12
30
171
29
164
1.78
2.24
2.1
1.4
—
—
—
0
0
57
385
1.50
2.20
1.6
1.4
208.0
288.3
ug/g
2.53
35
228
22
115
1.93
2.16
1.3
1.7
—
—
—
0
0
22
115
1.93
2.16
1.3
1.7
—
—
—
0
0
22
115
1.93
2.16
1.3
1.7
—
—
—
0
0
93
696
1.36
2.07
8.2
10.2
24.6
24.4
mmol/l
0.39
86
653
7
20
3.51
2.05
1.3
1.2
—
—
—
0
0
16
76
2.12
2.02
2.4
1.4
—
—
—
0
0
10
38
2.64
2.01
1.1
1.1
—
—
—
0
0
18
91
1.99
1.95
1.2
1.1
—
—
u/ml
—
0
0
54
372
1.47
1.93
1.3
1.2
—
—
—
0
0
54
372
1.47
1.93
1.3
1.3
—
—
—
0
0
121
956
1.29
1.87
2.5
2.2
12.7
12.6
nmol/l
0.05
108
850
8
28
2.87
1.86
1.6
2.4
—
—
—
0
0
44
293
1.52
1.86
4.9
2.9
41.9
35.3
umol/l
0.53
39
241
49
334
1.48
1.86
3.3
2.4
212.9
83.1
ug/min
1.11
26
209
42
277
1.53
1.85
3.0
2.2
124.0
128.4
g/l
0.56
30
206
80
598
1.36
1.82
5.2
3.8
23.8
24.0
mmol/l
0.25
72
542
50
345
1.46
1.79
1.1
1.1
8.0
7.0
u/ml
—
5
39
48
329
1.47
1.78
1.4
1.3
—
—
—
0
0
131
1055
1.26
1.75
2.3
2.8
58.4
66.1
ml/min/173m2
1.30
62
431
6
18
3.34
1.74
9.0
4.4
—
—
—
0
0
1302
12603
1.17
1.73
4.3
3.9
1.3
1.3
mmol/l
0.68
1201
11544
5
13
3.85
1.71
1.8
1.6
—
—
—
0
0
30
187
1.62
1.69
2.1
1.4
—
—
—
0
0
38
251
1.53
1.69
2.4
1.8
159.7
209.9
pmol/l
2.13
38
235
54
384
1.42
1.67
1.2
1.2
—
—
—
0
0
126
1017
1.26
1.66
4.6
3.7
100.3
88.6
ng/l
0.68
110
886
59
428
1.39
1.64
2.0
1.6
265.1
307.6
mu/l
0.69
53
385
54
386
1.41
1.63
1.2
1.2
—
—
—
0
0
241
2087
1.18
1.59
3.7
3.0
3.4
2.6
e6/l
0.38
131
1155
99
783
1.28
1.56
1.1
1.3
—
46.0
—
0
36
134
1621
0.81
1.54
5.1
4.5
34.3
32.4
%
1.30
103
1095
13
64
2.04
1.54
2.5
1.5
—
—
—
0
0
13
64
2.04
1.54
2.5
1.5
—
—
—
0
0
47
332
1.43
1.53
1.5
1.2
15.0
8.5
u/ml
—
10
51
6
21
2.86
1.50
1.2
1.1
—
—
—
0
0
15
79
1.91
1.49
1.3
1.2
—
—
—
0
0
46
326
1.42
1.48
1.5
1.2
25.5
2.4
u/ml
—
9
29
14
73
1.93
1.44
1.1
1.0
—
—
—
0
0
5
16
3.13
1.44
1.6
1.4
81.0
95.9
ng/l
—
5
16
57
422
1.36
1.43
4.9
4.2
3.9
3.9
mmol/l
0.72
50
395
31
204
1.53
1.43
1.4
3.5
1.0
1.2
%
0.39
24
164
9
39
2.31
1.43
1.7
2.1
—
—
—
0
0
54
397
1.37
1.42
1.7
1.7
—
—
—
0
0
10
46
2.18
1.40
1.5
2.0
7337.8
37682.3
e6/l
—
5
30
23
142
1.63
1.38
1.3
1.7
—
—
—
0
0
11
53
2.08
1.38
1.0
1.1
1414.8
1603.9
miu/ml
0.21
11
53
65
495
1.33
1.37
4.5
4.1
1.5
1.4
mmol/l
0.20
65
488
21
127
1.66
1.37
3.0
3.7
—
—
—
0
0
6
23
2.61
1.37
1.0
1.1
—
87.4
—
0
5
15
82
1.84
1.35
1.3
1.2
—
—
—
0
0
45
324
1.40
1.35
2.1
1.9
2.7
5.1
iu/l
2.84
15
115
18
105
1.72
1.33
2.2
1.2
4.7
0.6
u/ml
0.96
13
50
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
6
24
2.51
1.30
1.0
1.1
—
80.6
—
0
5
41
293
1.41
1.29
1.8
1.6
—
—
—
0
0
80
634
1.28
1.28
1.1
1.0
—
—
—
0
0
11
55
2.01
1.27
1.9
1.8
—
2190630.0
—
0
5
52
391
1.34
1.22
3.3
3.6
41.2
67.8
mg/l
0.91
39
323
34
238
1.44
1.21
1.3
1.2
256.2
252.8
u/ml
0.02
27
147
52
392
1.34
1.20
3.3
3.6
52.3
57.8
mg/l
0.10
39
324
13
71
1.84
1.19
1.5
1.5
—
—
—
0
0
51
384
1.34
1.19
3.2
3.5
1.3
1.6
ratio
—
5
36
11
57
1.94
1.17
1.0
1.9
—
—
—
0
0
17
102
1.67
1.16
1.2
1.4
10.7
13.3
mmol/l
—
8
23
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
72
1.81
1.15
1.0
1.2
—
—
—
0
0
11
58
1.90
1.12
1.3
3.4
77.0
124.6
umol/l
—
5
33
141
1208
1.18
1.11
2.1
1.9
—
—
—
0
0
5
21
2.38
1.09
1.4
1.2
—
—
—
0
0
30
210
1.44
1.08
1.1
1.3
—
—
—
0
0
27
186
1.46
1.06
1.2
1.1
—
—
—
0
0
45
340
1.33
1.05
1.3
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
1.4
—
24.8
—
0
23
15
92
1.64
0.97
3.9
1.7
—
—
—
0
0
38
284
1.35
0.97
1.3
1.4
—
—
—
0
0
24
165
1.46
0.97
1.2
1.3
—
—
—
0
0
0
32
0.00
0.95
0.0
1.3
—
—
—
0
0
40
303
1.33
0.94
1.8
1.7
28726.5
14068.6
e6/l
0.41
32
220
8
143
0.56
0.93
1.0
1.1
113.6
95.1
%
—
8
134
6
28
2.15
0.91
2.2
2.0
—
—
—
0
0
86
720
1.21
0.90
2.2
1.9
—
—
—
0
0
58
466
1.25
0.89
1.7
1.8
—
—
—
0
0
34
254
1.35
0.88
1.3
1.2
—
—
—
0
0
266
2426
1.12
0.88
2.8
3.0
0.8
0.8
ug/l
0.32
166
1574
8
42
1.91
0.88
1.9
2.8
—
—
—
0
0
8
42
1.91
0.88
1.9
2.8
—
—
—
0
0
36
272
1.33
0.87
1.3
1.3
—
—
—
0
0
36
272
1.33
0.87
1.3
1.3
—
—
—
0
0
8
44
1.82
0.86
2.1
1.3
8.8
8.9
ug/l
—
8
44
14
88
1.60
0.84
1.3
1.2
—
—
—
0
0
14
88
1.60
0.84
1.3
1.2
—
—
—
0
0
79
663
1.20
0.82
1.3
1.3
—
—
—
0
0
11
65
1.70
0.82
1.7
1.6
—
—
—
0
0
11
65
1.70
0.82
1.7
1.6
—
—
—
0
0
68
565
1.21
0.79
1.8
1.8
—
—
—
0
0
8
48
1.67
0.78
1.1
1.3
—
—
—
0
0
9
54
1.67
0.74
3.4
3.9
—
—
—
0
0
9
55
1.64
0.73
4.0
2.4
71.6
48.3
umol/l
—
9
46
92
794
1.17
0.72
1.7
1.6
—
—
—
0
0
9
56
1.61
0.72
1.2
1.1
—
—
—
0
0
10
60
1.67
0.72
1.2
1.1
144.1
207.1
iu/ml
—
10
60
35
273
1.29
0.71
3.2
1.8
0.7
0.9
nmol/l
0.74
29
225
7
41
1.71
0.70
1.3
1.2
—
—
—
0
0
150
1346
1.13
0.69
2.1
2.0
—
—
—
0
0
13
85
1.53
0.69
1.4
1.6
16.4
8.1
u/l
—
7
44
7
43
1.63
0.67
1.1
1.2
—
—
—
0
0
29
224
1.30
0.65
1.6
1.7
—
—
—
0
0
18
129
1.40
0.63
1.6
1.9
—
—
—
0
0
13
87
1.50
0.63
1.7
2.1
—
—
—
0
0
24
183
1.32
0.59
1.0
1.0
5.9
1.7
u/ml
—
9
76
8
53
1.51
0.58
1.5
1.9
—
—
—
0
0
8
53
1.51
0.58
1.0
2.0
—
—
—
0
0
8
53
1.51
0.58
1.0
2.0
—
—
—
0
0
8
53
1.51
0.58
1.0
2.0
—
—
—
0
0
18
132
1.37
0.57
1.4
1.8
—
—
—
0
0
6
37
1.62
0.55
1.3
1.2
—
—
—
0
0
10
65
1.54
0.55
1.0
1.1
—
—
—
0
0
9
62
1.45
0.53
1.1
2.2
—
—
—
0
0
41
341
1.21
0.52
1.6
1.3
9.9
9.7
u/l
0.04
34
272
34
278
1.23
0.51
2.0
1.6
—
—
—
0
0
15
109
1.38
0.51
1.5
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
52
447
1.17
0.48
3.5
2.6
0.4
0.3
u/ml
0.12
33
247
14
102
1.38
0.47
1.4
1.1
—
—
—
0
0
19
146
1.30
0.47
1.4
1.7
63.4
58.8
%
0.20
12
95
10
68
1.47
0.47
1.4
3.6
—
—
—
0
0
36
429
0.84
0.46
1.3
1.4
—
—
—
0
0
19
147
1.30
0.45
1.4
1.3
274.2
298.9
pmol/l
0.20
14
118
86
773
1.12
0.43
1.8
1.5
—
—
—
0
0
58
508
1.15
0.43
4.0
3.4
69.9
2633.7
u/ml
0.73
50
439
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
27
221
1.23
0.42
1.2
1.1
10.2
1.7
u/ml
1.05
16
89
22
176
1.25
0.42
1.5
1.5
—
—
—
0
0
34
287
1.19
0.40
5.9
3.6
27.6
25.8
mg/l
0.09
27
185
20
159
1.26
0.40
1.0
1.1
—
—
—
0
0
39
335
1.17
0.38
1.3
1.4
—
—
—
0
0
15
116
1.30
0.37
2.7
2.2
—
—
—
0
0
34
290
1.18
0.37
1.5
1.6
697.6
544.0
e6/l
0.12
27
235
34
290
1.18
0.37
1.4
1.6
5.9
7.7
e6/l
0.25
27
227
26
308
0.84
0.34
1.7
1.5
—
—
—
0
0
17
136
1.25
0.33
1.0
1.2
41.3
51.8
u/l
1.11
12
100
14
109
1.29
0.33
2.4
2.2
1.3
1.9
u/field
—
7
49
10
75
1.34
0.30
1.7
2.2
—
172.4
—
0
14
25
292
0.85
0.29
1.6
1.4
—
—
—
0
0
25
292
0.85
0.29
1.6
1.4
—
—
—
0
0
25
292
0.85
0.29
1.6
1.4
—
—
—
0
0
25
291
0.86
0.28
1.6
1.4
—
—
—
0
0
8
66
1.21
0.26
2.3
2.6
—
—
—
0
0
13
104
1.25
0.26
1.4
1.1
416.0
155.0
titre
—
5
18
45
499
0.90
0.26
1.7
1.7
5.0
4.2
mg/l
0.12
33
360
5
75
0.67
0.26
2.0
1.1
—
—
—
0
0
20
170
1.18
0.24
1.3
1.5
—
—
—
0
0
20
170
1.18
0.24
1.3
1.5
—
—
—
0
0
17
201
0.84
0.23
1.0
1.1
—
—
—
0
0
20
171
1.17
0.23
1.3
1.5
—
—
—
0
0
167
1597
1.05
0.23
1.9
1.8
1.6
1.5
%
0.45
153
1393
60
554
1.09
0.22
1.6
1.3
24.1
28.8
iu/l
0.63
50
468
25
219
1.14
0.22
1.7
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
8
102
0.78
0.21
1.1
1.0
325.6
286.3
mg/l
—
8
90
20
173
1.16
0.21
1.3
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
5.7
—
—
—
0
0
211
2037
1.04
0.20
1.5
1.4
—
—
—
0
0
6
51
1.18
0.19
2.3
2.0
13.2
190.8
ug/l
—
6
41
20
175
1.14
0.18
1.2
1.1
—
—
—
0
0
11
132
0.83
0.18
3.0
2.7
—
—
—
0
0
7
60
1.17
0.17
1.0
1.3
—
—
—
0
0
7
60
1.17
0.17
1.0
1.3
—
—
—
0
0
1222
12141
1.03
0.16
20.1
15.0
38.9
39.7
%
2.01
845
8708
8
73
1.10
0.15
2.9
1.8
0.9
3.0
u/field
—
8
55
45
421
1.07
0.14
1.5
1.4
—
—
—
0
0
27
295
0.91
0.14
1.1
1.4
112.7
224.9
pmol/l
0.97
27
290
14
122
1.15
0.13
1.1
1.2
—
—
—
0
0
8
97
0.82
0.13
1.1
1.2
—
—
—
0
0
8
97
0.82
0.13
1.1
1.2
—
—
—
0
0
8
97
0.82
0.13
1.1
1.2
—
—
—
0
0
18
200
0.90
0.12
1.2
1.2
3.9
3.5
u/ml
—
7
62
12
104
1.15
0.12
1.8
1.6
1.0
1.0
g/l
0.00
12
104
26
239
1.09
0.12
1.7
1.6
—
—
—
0
0
10
86
1.16
0.11
1.1
1.0
—
—
—
0
0
19
173
1.10
0.10
1.2
1.5
—
—
—
0
0
19
173
1.10
0.10
1.2
1.5
—
—
—
0
0
16
145
1.10
0.09
1.5
1.4
19035.6
87198.4
e6/l
—
9
87
8
74
1.08
0.07
13.6
10.7
0.6
0.6
mmol/l
—
8
67
10
112
0.89
0.07
1.0
1.0
—
—
—
0
0
11
122
0.90
0.07
1.3
1.1
—
—
—
0
0
10
89
1.12
0.07
1.3
1.2
29.0
14.2
u/l
—
10
83
18
167
1.08
0.07
1.8
2.5
20.3
25.7
mg/l
—
9
45
8
95
0.84
0.06
1.1
1.2
—
—
—
0
0
8
95
0.84
0.06
1.1
1.2
—
—
—
0
0
17
159
1.07
0.05
1.9
1.5
—
—
—
0
0
161
1631
0.99
0.04
9.6
7.1
—
—
—
0
0
36
373
0.96
0.04
1.1
1.3
189.6
244.8
miu/ml
0.41
11
177
14
131
1.07
0.03
1.0
1.1
—
—
—
0
0
28
288
0.97
0.02
2.7
3.2
0.7
0.8
nmol/l
0.39
18
225
12
113
1.06
0.02
1.0
1.1
—
—
—
0
0
53
522
1.02
0.01
1.9
1.5
—
—
—
0
0
19
196
0.97
0.00
1.3
1.2
2.3
4.6
u/ml
—
7
85
16
162
0.99
0.00
1.5
1.4
1231.9
1712.8
e6/l
0.37
11
112
23
228
1.01
0.00
2.9
3.8
24.9
25.8
u/ml
0.05
23
222
6
60
1.00
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.4
—
0
7
7
75
0.93
0.00
1.6
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
13.5
—
—
—
0
0
5
59
0.85
0.00
2.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
2.4
—
0
5
35
350
1.00
0.00
1.5
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
17
170
1.00
0.00
1.2
1.4
6.4
7.5
mmol/l
—
9
124
7
72
0.97
0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
7.6
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_HERPESKERATITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_HERPESKERATITIS | 1.265 [1.13, 1.41] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.337 |
During the follow-up period (1.1.1998 — 31.12.2019), 1095 out of 6103 females with H7_HERPESKERATITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_HERPESKERATITIS | 1.22 [1.09, 1.37] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 1073 out of 5181 males with H7_HERPESKERATITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_HERPESKERATITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.162% | 0.24% |
| 5 | 0.728% | 1.368% |
| 10 | 1.919% | 3.58% |
| 15 | 3.975% | 6.901% |
| 20 | 6.792% | 11.807% |
Relationships between endpoints
↥Index endpoint: H7_HERPESKERATITIS – Herpesviral keratitis and keratoconjunctivitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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