Herpesviral keratitis and keratoconjunctivitis

H7_HERPESKERATITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1719

4. Check minimum number of events

None

1719

5. Include endpoints

None

1719

6. Filter based on genotype QC (FinnGen only)

1663

Control definitions (FinnGen only)

Control exclude
H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12217 6572 5592
Only index persons 11504 6258 5246
Unadjusted period prevalence (%)
Whole population 0.17 0.19 0.16
Only index persons 0.22 0.23 0.20
Median age at first event (years)
Whole population 53.84 55.22 52.20
Only index persons 53.05 54.42 51.40

-FinnGen-

Key figures

All Female Male
Number of individuals 1663 941 722
Unadjusted period prevalence (%) 0.33 0.33 0.33
Median age at first event (years) 56.68 54.32 59.75

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1719
Matched controls
17190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01AD03
ATC
aciclovir; ophthalmic
290.3
307.7
1295
179
H16.0
ICD-10 Finland
Corneal ulcer
48.5
307.7
380
100
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
3005.2
307.7
472
*
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
16384.0
307.7
1446
*
J05AB01
ATC
aciclovir; systemic
10.8
307.7
1077
2308
H16.9
ICD-10 Finland
Keratitis, unspecified
439.5
302.9
295
8
J05AB11
ATC
valaciclovir; oral
6.5
287.8
633
1417
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
5.1
228.9
1167
5054
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
285.9
223.9
224
9
B00.5
ICD-10 Finland
Herpesviral ocular disease
235.7
186.4
189
9
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
64.0
164.5
91
15
H04.10
ICD-10 Finland
Dry eye syndrome
5.2
161.4
399
949
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.3
129.6
844
3867
B00.10
ICD-10 Finland
Herpes simplex facialis
20.2
107.4
83
43
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
4.6
83.2
213
508
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
223.4
83.1
85
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.6
78.3
296
935
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.9
72.4
434
1797
H57.1
ICD-10 Finland
Ocular pain
6.2
71.9
127
217
B02.3
ICD-10 Finland
Zoster ocular disease
37.6
70.8
44
12
S01ED01
ATC
timolol; ophthalmic
6.2
68.5
122
210
F01
ICPC
Eye pain
6.7
67.5
110
173
S01BA01
ATC
dexamethasone; ophthalmic
6.2
66.5
117
199
H20.1
ICD-10 Finland
Chronic iridocyclitis
673.4
66.4
65
*
H16.2
ICD-10 Finland
Keratoconjunctivitis
123.4
66.4
71
6
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
17.2
66.2
55
33
S01FA04
ATC
cyclopentolate; ophthalmic
17.2
66.2
55
33
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
9.8
65.5
77
82
H15.1
ICD-10 Finland
Episcleritis
20.1
63.5
49
25
S01ED51
ATC
timolol, combinations; ophthalmic
3.7
60.7
211
626
D11AX14
ATC
[U] tacrolimus
22.0
60.5
45
21
H18.8
ICD-10 Finland
Other specified disorders of cornea
207.1
58.4
60
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
24.7
57.7
41
17
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.8
55.2
323
1303
S01EC01
ATC
acetazolamide; systemic
7.5
55.0
80
111
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
71.3
54.5
62
9
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.9
53.5
172
482
D11AH01
ATC
tacrolimus; topical
12.7
53.1
52
42
H22.0*B00.5
ICD-10 Finland
Herpesviral iridocyclitis
+∞
52.4
50
*
S01EA05
ATC
brimonidine; ophthalmic
6.4
52.2
88
143
S01AX11
ATC
[U] ofloxacin
5.0
50.6
113
239
H17.8
ICD-10 Finland
Other corneal scars and opacities
448.9
44.4
44
*
S01BA04
ATC
prednisolone; ophthalmic
7.1
43.9
67
98
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
82.3
43.1
48
6
S01AA01
ATC
chloramphenicol; ophthalmic
3.9
42.9
134
367
S01GX01
ATC
cromoglicic acid; ophthalmic
2.3
42.2
407
2055
H13.1*B00.5
ICD-10 Finland
Herpesviral conjunctivitis
115.5
41.9
45
*
Z94.7
ICD-10 Finland
Corneal transplant status
417.3
41.3
41
*
S01EA03
ATC
apraclonidine; ophthalmic
10.5
39.7
44
43
F29
ICPC
Eye symptom/complaint other
2.8
39.1
210
802
H16.8
ICD-10 Finland
Other keratitis
204.6
39.0
40
*
H17.1
ICD-10 Finland
Other central corneal opacity
+∞
36.6
35
*
L20.0
ICD-10 Finland
Besnier prurigo
3.1
36.2
164
569
H02AB06
ATC
prednisolone; systemic
1.9
35.8
860
5959
05405
ICD-8 Finland
Herpes simplex, Kerato-conjunctivitis herpetica
126.0
34.8
37
*
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
+∞
34.5
33
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.7
34.3
211
862
CG2S4
NOMESCO Finland
Photography of cornea
66.4
34.1
39
6
XCH00
NOMESCO Finland
Eye pressure measurement
3.5
33.2
118
352
D06BB03
ATC
aciclovir; topical
3.5
33.2
121
367
F02
ICPC
Red eye
3.7
33.1
107
300
H01.0
ICD-10 Finland
Blepharitis
3.1
32.9
150
522
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.6
32.7
205
845
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
318.5
30.9
31
*
D07AA02
ATC
hydrocortisone; topical
2.2
30.0
277
1356
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.5
30.0
205
880
H16.3
ICD-10 Finland
Interstitial and deep keratitis
+∞
29.2
28
*
E000002, ,
ATC
2.4
28.7
221
1001
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
9.1
27.8
34
38
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
6.4
27.5
46
74
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
27.5
550
3525
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.6
27.1
171
705
H18.1
ICD-10 Finland
Bullous keratopathy
275.2
26.8
27
*
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
61.0
26.0
30
5
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
31.5
26.0
34
11
CD2S4
NOMESCO Finland
Photography of eye
10.2
25.6
29
29
L04AA01
ATC
[U] ciclosporin
6.8
25.6
40
60
S01BA07
ATC
fluorometholone; ophthalmic
5.7
24.8
46
82
F03
ICPC
Eye discharge
2.7
24.7
135
517
H18.6
ICD-10 Finland
Keratoconus
131.9
24.7
26
*
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.7
24.4
139
544
H10
ICD-10 Finland
Conjunctivitis
2.6
23.7
142
570
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
88.0
23.7
26
*
114
Kela drug reimbursment
Glaucoma
2.4
23.6
173
764
TCG10
NOMESCO Finland
Removal of sutures from cornea
27.1
23.6
32
12
J01DB01
ATC
cefalexin; oral
1.9
23.5
1410
12101
H26.4
ICD-10 Finland
After-cataract
2.3
23.4
190
878
S01EE01
ATC
latanoprost; ophthalmic
2.7
23.2
133
522
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
+∞
23.0
22
*
H20.8
ICD-10 Finland
Other iridocyclitis
233.0
22.7
23
*
E0000UV, ,
ATC
1.7
22.7
701
5015
S01FA02
ATC
scopolamine; ophthalmic
19.2
22.6
34
18
S01EC04
ATC
brinzolamide; ophthalmic
3.2
21.7
90
296
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.6
21.6
126
499
H03.1
ICD-10 Finland
Involvement of eyelid in other infectious diseases classified elsewhere
43.9
21.4
26
6
S01EC54
ATC
brinzolamide, combinations; ophthalmic
6.0
21.4
38
65
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
4.5
21.4
52
118
B00.11
ICD-10 Finland
Herpes simplex labialis
4.9
20.9
46
96
H26.2
ICD-10 Finland
Complicated cataract
5.8
20.7
38
67
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
212.5
20.6
21
*
H03.1*B02.3
ICD-10 Finland
Zoster blepharitis
18.5
20.4
31
17
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.1
20.0
42
84
E000001, ,
ATC
1.8
19.8
347
2106
B00.1
ICD-10 Finland
Herpesviral vesicular dermatitis
6.3
19.8
33
53
D11AX15
ATC
[U] pimecrolimus
29.3
19.7
26
9
L04AD01
ATC
ciclosporin; systemic
4.6
19.4
46
102
D07AC01
ATC
betamethasone; topical
1.6
19.2
605
4303
WX140
NOMESCO Finland
Parabulbar anesthesy
2.8
19.0
99
370
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.1
18.3
189
959
H3603, E103,
ICD-10 Finland
6.3
18.0
30
48
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
17.7
17
*
H18.2
ICD-10 Finland
Other corneal oedema
+∞
17.7
17
*
R03AC02
ATC
salbutamol; inhalant
1.6
17.6
908
7193
H40.0
ICD-10 Finland
Glaucoma suspect
2.2
16.7
144
681
D11AH02
ATC
pimecrolimus; topical
16.5
16.6
26
16
D07AC13
ATC
mometasone; topical
1.6
16.6
480
3321
F73
ICPC
Eye infection/inflammation other
3.9
16.5
48
125
L04AX01
ATC
azathioprine; systemic
2.9
16.4
78
278
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
5.9
15.7
28
48
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
+∞
15.6
15
*
R06AE07
ATC
cetirizine; oral
1.5
15.6
708
5406
TQW80
NOMESCO Finland
Local dermatologic skincare
3.4
15.5
57
174
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.6
15.5
50
140
S01BC05
ATC
ketorolac; ophthalmic
2.8
15.4
76
276
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
15.3
746
5776
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
15.3
430
2946
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
15.1
145
714
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
15.1
481
3392
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
15.0
576
4234
H02AB07
ATC
prednisone; oral
1.8
14.8
233
1361
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
14.8
331
2137
H13.1
ICD-10 Finland
Conjunctivitis in infectious and parasitic diseases classified elsewhere
57.2
14.8
17
*
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
14.6
14
*
XCK00
NOMESCO Finland
Perimetry
2.3
14.5
109
486
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
36.4
14.4
18
5
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
36.4
14.4
18
5
L04AX03
ATC
methotrexate; systemic
2.0
14.3
159
827
S01EX03, ,
ATC
3.7
14.3
45
124
H10.2
ICD-10 Finland
Other acute conjunctivitis
4.7
14.3
33
72
B02.9
ICD-10 Finland
Zoster without complication
2.2
14.2
121
568
R50.9
ICD-10 Finland
Fever, unspecified
1.8
14.2
252
1524
H20
ICD-10 Finland
Iridocyclitis
19.3
14.2
21
11
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.7
14.2
44
120
E000007, ,
ATC
2.4
14.1
100
434
127
Kela drug reimbursment
Transplant complication
4.3
13.9
36
86
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
13.8
219
1282
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
13.7
165
883
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.9
13.7
197
1118
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.6
13.7
45
128
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
13.5
829
6668
E000006, ,
ATC
2.2
13.5
123
594
H16
ICD-10 Finland
Keratitis
26.0
13.4
18
7
L20
ICD-10 Finland
Atopic dermatitis
3.1
13.3
55
181
S01BC03
ATC
diclofenac; ophthalmic
3.4
13.2
46
136
S01EC03
ATC
dorzolamide; ophthalmic
4.5
12.9
31
70
J01CA04
ATC
amoxicillin; systemic
1.6
12.9
1329
11803
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
12.8
740
5862
H191, B023,
ICD-10 Finland
+∞
12.5
12
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
12.5
12
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.4
12.5
44
131
H15.0
ICD-10 Finland
Scleritis
130.9
12.4
13
*
N03AX12
ATC
[U] gabapentin; oral
1.7
12.4
268
1710
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
12.2
306
2027
S01
ICPC
Pain/tenderness of skin
2.4
12.1
82
350
S01EE05
ATC
tafluprost; ophthalmic
2.7
12.1
65
248
ZXA10
NOMESCO Finland
Bilateral
1.6
12.0
292
1917
N02BE01
ATC
paracetamol; systemic, rectal
1.7
11.9
1478
13526
L04AA06
ATC
mycophenolic acid; systemic
3.6
11.8
38
107
R03BA05
ATC
fluticasone; inhalant
1.6
11.7
288
1896
H18.4
ICD-10 Finland
Corneal degeneration
30.2
11.6
15
5
D02AE01
ATC
carbamide; topical
2.1
11.6
109
533
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.6
686
5432
E000004, ,
ATC
3.4
11.5
40
118
D07CC01
ATC
betamethasone and antibiotics; topical
1.7
11.5
210
1277
J01DA01
ATC
[U] cefalexin
1.4
11.5
996
8436
H190, B005,
ICD-10 Finland
+∞
11.5
11
*
CGF35
NOMESCO Finland
Repair of cornea using graft
+∞
11.5
11
*
J01MA14
ATC
moxifloxacin; systemic
1.9
11.5
152
840
D07AB08
ATC
desonide; topical
1.8
11.4
178
1034
H19.2*B30.0
ICD-10 Finland
Epidemic keratoconjunctivitis
120.8
11.4
12
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.2
11.3
43
135
A10AB05
ATC
insulin aspart; parenteral
2.0
11.2
128
672
XQ802
NOMESCO Finland
Epicutan test
2.5
11.1
71
295
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
8.1
11.1
24
30
H02AB04
ATC
methylprednisolone; systemic
1.7
11.1
227
1426
SPAT1301
SPAT
No procedures
1.5
11.0
483
3607
A10AA01, ,
ATC
3.0
11.0
49
169
H10.4
ICD-10 Finland
Chronic conjunctivitis
4.7
11.0
25
54
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
5.4
10.9
21
39
S01XA18
ATC
ciclosporin; ophthalmic
8.3
10.8
23
28
B00.0
ICD-10 Finland
Eczema herpeticum
9.6
10.8
21
22
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.9
10.7
31
81
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.8
10.6
52
189
N03AX16
ATC
[U] pregabalin
1.5
10.5
366
2602
C03CA01
ATC
furosemide; systemic
1.5
10.5
460
3428
H17.0
ICD-10 Finland
Adherent leukoma
+∞
10.4
10
*
H3601, E103,
ICD-10 Finland
5.5
10.4
20
37
T89
ICPC
Diabetes insulin dependent
2.4
10.4
68
286
S71
ICPC
Herpes simplex
5.2
10.3
21
41
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
10.3
211
1324
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
10.3
226
1444
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
10.3
467
3502
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
10.3
339
2383
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.2
10.2
83
383
E000003, ,
ATC
2.3
10.1
77
346
A10AB01
ATC
insulin (human); parenteral
2.5
10.1
60
241
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
10.1
607
4791
A02BC02
ATC
pantoprazole; systemic
1.4
10.0
1077
9363
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
9.2
10.0
20
22
S01FA01
ATC
atropine; ophthalmic
10.1
10.0
19
19
R06AE09
ATC
levocetirizine; oral
1.6
9.9
221
1416
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
9.8
509
3905
A10AE04
ATC
insulin glargine; parenteral
1.8
9.7
157
923
D02AX
ATC
Other emollients and protectives
2.7
9.6
52
199
J01AA02
ATC
doxycycline; systemic
1.4
9.6
1244
11128
S01AA12
ATC
tobramycin; ophthalmic
15.1
9.5
15
10
R42
ICD-10 Finland
Dizziness and giddiness
1.5
9.5
348
2498
D07AD01
ATC
clobetasol; topical
1.6
9.4
253
1696
E85.80
ICD-10 Finland
Meretoja sick
+∞
9.4
9
*
J01DA09
ATC
[U] cefadroxil
1.5
9.4
407
3019
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.5
9.4
60
250
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
9.4
448
3384
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
8.1
9.3
20
25
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.9
9.3
20
41
UJF32
NOMESCO Finland
Coloscopy
1.5
9.3
400
2960
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
9.3
303
2121
S29
ICPC
Skin symptom/complaint other
1.5
9.3
287
1986
H04AA01
ATC
glucagon; nasal, parenteral
3.1
9.3
38
125
A46
ICD-10 Finland
Erysipelas
1.6
9.2
225
1474
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.3
9.2
65
283
SPAT1260
SPAT
Consultation of another employee
1.6
9.2
265
1805
S87
ICPC
Dermatitis/atopic eczema
2.9
9.2
41
142
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.8
9.1
46
170
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.4
9.1
22
50
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
9.1
111
598
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
9.0
289
2014
F13
ICPC
Eye sensation abnormal
2.6
8.9
51
201
R06AX13
ATC
loratadine; oral
1.6
8.8
224
1482
D07BC01
ATC
betamethasone and antiseptics; topical
1.7
8.8
184
1160
L01BA01
ATC
methotrexate; systemic
2.5
8.8
56
233
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
8.8
201
1297
J01FA06
ATC
roxithromycin; oral
1.4
8.8
609
4895
J01FF01
ATC
clindamycin; systemic
1.4
8.7
414
3118
CKD40
NOMESCO Finland
Endophotocoagulation of retina
3.6
8.7
28
79
Z3231
NOMESCO Finland
Registered nurse
1.4
8.7
411
3092
NHQ40
NOMESCO Finland
Amputation of toe
3.3
8.6
32
99
L88
ICPC
Rheumatoid/seropositive arthritis
2.4
8.6
58
248
H01
ICPC
Ear pain/earache
1.7
8.5
163
1003
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
8.5
621
5023
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
20.1
8.5
12
6
N05BB01
ATC
hydroxyzine; systemic
1.9
8.4
101
541
R02
ICPC
Shortness of breath/dyspnoea
1.6
8.4
198
1287
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.5
8.4
20
45
H02AB09
ATC
hydrocortisone; systemic
2.8
8.4
40
144
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
8.3
8
*
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
+∞
8.3
8
*
3604
FHL
Penetration of the cornea
+∞
8.3
8
*
A02BC05
ATC
esomeprazole; systemic
1.4
8.2
620
5039
D09AB01
ATC
zinc bandage without supplements; topical
2.9
8.1
36
124
H10.8
ICD-10 Finland
Other conjunctivitis
4.6
8.1
19
42
S01KA02
ATC
hypromellose; ophthalmic
3.1
8.1
32
103
R06AX27
ATC
desloratadine; oral
1.4
8.1
412
3135
CFD10
NOMESCO Finland
Repair of conjunctiva
22.1
8.0
11
5
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.0
8.0
35
120
R03DC03
ATC
montelukast; oral
1.5
7.9
249
1727
UDC00
NOMESCO Finland
Ear microscopy
1.8
7.9
114
648
R06.0
ICD-10 Finland
Dyspnoea
1.4
7.9
405
3086
ZXA05
NOMESCO Finland
Left side
1.4
7.9
368
2758
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.1
7.8
70
337
J01FA10
ATC
azithromycin; systemic
1.3
7.8
860
7376
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.8
584
4730
S01EE03
ATC
bimatoprost; ophthalmic
2.6
7.8
43
167
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
9.4
7.8
15
16
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
7.8
138
833
H25.8
ICD-10 Finland
Other senile cataract
1.7
7.7
158
991
H26.02
ICD-10 Finland
Presenil cataract
2.6
7.7
44
174
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
7.7
269
1906
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.7
7.7
40
151
R01AD12
ATC
fluticasone furoate; nasal
1.4
7.7
456
3559
P01BA02
ATC
hydroxychloroquine; oral
1.8
7.7
116
669
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
7.7
432
3342
A07AA02
ATC
nystatin; oral
1.9
7.6
87
458
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.7
7.6
132
791
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.2
7.6
61
281
R03BA02
ATC
budesonide; inhalant
1.5
7.6
272
1937
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
8.9
7.5
15
17
SPAT1263
SPAT
Sampling
1.3
7.5
626
5145
L17
ICPC
Foot/toe symptom/complaint
1.4
7.5
424
3280
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
7.5
137
834
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.4
7.5
49
207
SPAT1325
SPAT
Vaccination
1.4
7.5
487
3855
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
80.4
7.4
8
*
H22.0
ICD-10 Finland
Iridocyclitis in infectious and parasitic diseases classified elsewhere
80.4
7.4
8
*
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
80.4
7.4
8
*
J01MA12
ATC
levofloxacin; systemic
1.5
7.4
275
1971
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
7.4
345
2581
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.4
369
2795
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
7.4
54
240
D06BX01
ATC
metronidazole; topical
1.6
7.4
161
1027
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
7.3
7
*
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
+∞
7.3
7
*
0544B
ICD-9 Finland
Herpes simplex, With ophthalmic complications[KERATITIS DENDRITICA, HERPETICA]
+∞
7.3
7
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
9.4
7.3
14
15
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
9.4
7.3
14
15
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.2
7.3
19
46
XCW10
NOMESCO Finland
Assessment of vision
3.3
7.3
26
79
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.7
7.2
38
144
H01.89
ICD-10 Finland
Other specified inflammation of eyelids
6.3
7.2
18
29
R03AC13
ATC
formoterol; inhalant
1.9
7.2
83
439
Z94.0
ICD-10 Finland
Kidney transplant status
3.7
7.2
22
60
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
4.5
7.2
17
38
A10AE05
ATC
insulin detemir; parenteral
1.9
7.2
84
447
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
7.1
167
1083
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
20.1
7.1
10
5
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.9
7.1
91
498
D06
ICPC
Abdominal pain localized other
1.7
7.1
124
745
F70
ICPC
Conjunctivitis infectious
2.5
7.1
42
169
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
12.1
7.1
12
10
M79.6
ICD-10 Finland
Pain in limb
1.3
7.1
620
5125
A10AA02, ,
ATC
2.3
7.0
52
233
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
6.9
387
2982
J46
ICD-10 Finland
Status asthmaticus
2.4
6.9
47
202
S01EE04
ATC
travoprost; ophthalmic
2.8
6.9
33
119
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
4.0
6.9
19
48
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.8
6.9
34
125
S01GX06
ATC
emedastine; ophthalmic
3.6
6.9
22
62
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.9
629
5226
R03AC03
ATC
terbutaline; inhalant
1.5
6.8
207
1423
SPAT1312
SPAT
General health counselling
1.4
6.8
455
3607
H02.4
ICD-10 Finland
Ptosis of eyelid
2.3
6.8
48
210
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.8
414
3235
395
Kela drug reimbursment
Dupilumab
11.0
6.8
12
11
S01EB01
ATC
pilocarpine; ophthalmic
6.1
6.8
17
28
H53.1
ICD-10 Finland
Subjective visual disturbances
1.8
6.8
97
551
R06AX22
ATC
ebastine; oral
1.5
6.8
249
1781
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
40.2
6.8
8
*
CBH25
NOMESCO Finland
Tarsorrhaphy
40.2
6.8
8
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
2.8
6.7
33
121
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.7
179
1197
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
7.2
6.7
15
21
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
6.7
327
2465
H52.2
ICD-10 Finland
Astigmatism
2.9
6.6
30
105
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
2.6
6.6
38
151
ZXE00
NOMESCO Finland
One hour or less
1.3
6.6
572
4709
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.6
254
1833
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.5
594
4921
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.5
205
1420
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
6.9
6.5
15
22
A07EC01
ATC
sulfasalazine; oral, rectal
1.7
6.5
110
656
B02.8
ICD-10 Finland
Zoster with other complications
5.3
6.5
18
34
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.9
6.4
77
413
H19.3
ICD-10 Finland
Keratitis and keratoconjunctivitis in other diseases classified elsewhere
70.1
6.4
7
*
H40.8
ICD-10 Finland
Other glaucoma
7.4
6.4
14
19
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
6.4
161
1062
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2.2
6.4
54
255
H02.1
ICD-10 Finland
Ectropion of eyelid
3.8
6.4
19
51
R51.80
ICD-10 Finland
Headache
1.5
6.4
220
1554
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.1
6.4
60
296
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
6.6
6.3
15
23
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
6.3
325
2467
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
6.3
6
*
36398
ICD-8 Finland
Keratitis, Alia definita
+∞
6.3
6
*
05403
ICD-8 Finland
Herpes simplex, Cutaneus (Eczema herpeticum)
+∞
6.3
6
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
6.2
121
750
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
6.2
161
1070
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.2
669
5664
SPAT1254
SPAT
Administration of medicine
1.5
6.2
210
1478
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
6.2
192
1327
CKC15
NOMESCO Finland
Panretinal photocoagulation
4.0
6.2
17
43
H25.0
ICD-10 Finland
Senile incipient cataract
1.8
6.1
90
515
B30.9
ICD-10 Finland
Viral conjunctivitis, unspecified
7.7
6.1
13
17
M45
ICD-10 Finland
Ankylosing spondylitis
2.9
6.1
28
99
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
6.1
184
1264
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.2
6.1
48
221
H54.4
ICD-10 Finland
Blindness, monocular
8.6
6.1
12
14
CHD99
NOMESCO Finland
Other filtering operation
10.1
6.0
11
11
D11AH05
ATC
dupilumab; topical
10.1
6.0
11
11
H13
ICPC
Plugged feeling ear
1.4
6.0
274
2036

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
34
22.38
98.74
1.5
1.6
—
—
—
0
0
380
1625
2.72
58.33
2.1
1.7
—
—
—
0
0
911
6894
1.68
24.27
7.7
5.5
0.61
0.58
e9/l
2.61
828
5960
933
7106
1.68
24.24
7.8
5.5
1.84
1.95
e9/l
1.37
853
6278
866
6471
1.68
24.17
8.4
6.1
—
—
—
0
0
911
6908
1.68
23.96
7.8
5.5
0.04
0.04
e9/l
0.19
828
5969
934
7150
1.67
23.50
7.9
5.8
0.21
0.19
e9/l
1.79
853
6261
832
6285
1.63
21.24
7.9
5.7
0.66
0.67
%
0.10
792
5861
853
6487
1.63
21.16
8.0
5.6
2.98
2.84
%
1.08
814
6063
856
6519
1.62
21.08
8.3
5.9
8.71
8.60
%
0.49
820
6098
1016
8074
1.63
21.00
11.4
8.7
4.27
4.13
e9/l
1.04
930
7051
871
6707
1.61
20.15
8.0
5.7
26.63
27.61
%
1.97
838
6293
861
6615
1.60
20.09
7.8
5.5
58.15
57.47
%
0.95
831
6198
28
40
7.10
18.68
1.2
1.5
—
—
—
0
0
1260
10785
1.63
17.30
9.7
7.4
80.65
78.11
u/l
0.74
1202
10143
779
6004
1.54
16.86
6.0
4.7
34.99
35.49
g/l
1.57
727
5570
1206
10271
1.58
16.34
5.4
3.9
13.15
12.22
mm/h
1.32
1121
9479
530
3813
1.56
15.26
5.4
4.2
—
—
—
0
0
865
6915
1.51
15.20
8.2
6.7
1.21
1.21
mmol/l
0.26
745
5877
1135
9610
1.53
15.09
5.5
4.2
—
—
—
0
0
590
4370
1.53
14.80
3.2
2.5
53.21
76.65
u/l
0.70
554
4055
563
4173
1.52
13.88
2.2
2.2
158.82
237.01
u/l
1.55
525
3915
855
6913
1.47
13.62
4.5
3.6
0.00
0.00
estimate
0.80
173
1247
847
6847
1.47
13.43
4.5
3.6
0.00
0.00
estimate
0.75
196
1373
382
2616
1.59
13.35
1.7
1.4
2.64
2.45
g/l
0.67
250
1592
844
6840
1.46
13.08
6.1
4.8
0.00
0.00
estimate
0.50
184
1288
984
8226
1.46
12.87
6.0
4.8
6.73
6.74
mmol/l
0.00
930
7709
806
6497
1.45
12.72
16.3
15.3
1.22
1.27
inr
0.93
289
1874
309
2047
1.62
12.30
2.7
2.0
—
—
—
0
0
889
7345
1.44
12.03
7.4
6.1
11.74
11.49
umol/l
0.17
854
6971
565
4297
1.47
11.87
3.4
3.1
—
—
—
0
0
1075
9226
1.44
11.63
5.3
4.4
2252.01
2260.52
e6/l
0.00
23
132
758
6111
1.43
11.59
12.9
9.2
0.00
0.00
e9/l
1.39
647
4993
1518
14036
1.70
11.14
20.9
14.0
22.94
24.19
mg/l
0.75
1289
11078
277
1830
1.61
11.07
3.1
2.5
21.71
23.23
%
1.11
239
1572
472
3507
1.48
11.02
2.6
2.1
3.07
3.03
mg/l
0.14
427
2964
537
4096
1.45
10.93
5.2
3.9
7.40
7.40
ph
0.21
122
773
746
6046
1.41
10.83
3.4
2.8
132.06
127.12
ug/l
0.23
699
5566
687
5488
1.42
10.83
4.1
3.3
5.97
5.83
ph
0.47
33
396
405
2929
1.50
10.77
3.5
2.5
5.33
6.02
e6/l
0.41
372
2643
312
2147
1.55
10.43
3.1
2.4
12.35
13.18
umol/l
1.32
290
1996
623
4925
1.42
10.28
4.8
3.6
69.45
114.37
e6/l
1.19
463
3499
289
1963
1.57
10.22
3.0
2.4
2.36
2.32
g/l
0.67
269
1817
1210
10737
1.43
10.02
4.5
4.0
14.57
14.77
pmol/l
2.05
1118
9774
147
840
1.82
9.97
1.9
1.2
1629.24
177.85
u/ml
1.28
133
772
417
3076
1.47
9.95
1.8
1.7
1.13
1.19
mg/l
0.14
315
2336
35
105
3.38
9.88
3.0
2.1
1.15
1.22
e9/l
0.19
30
98
29
77
3.81
9.78
3.2
2.2
0.21
0.21
e9/l
0.06
24
70
407
3015
1.46
9.44
1.4
1.2
2.64
1.49
u/ml
0.82
121
814
29
80
3.67
9.28
3.2
2.1
504.88
614.03
e6/l
0.40
24
71
24
58
4.18
9.19
1.2
1.3
—
—
—
0
0
199
1273
1.64
8.99
4.8
3.6
2.21
1.95
mmol/l
0.39
163
1045
40
139
2.92
8.89
1.1
1.2
—
—
—
0
0
137
795
1.79
8.84
2.1
1.7
1.16
1.45
g/l
1.39
126
736
169
1042
1.69
8.80
4.4
4.0
0.60
0.68
%
0.24
50
344
534
4205
1.39
8.69
4.3
3.2
77.18
82.13
e6/l
0.05
429
3249
696
5726
1.36
8.61
2.0
2.0
95.82
95.00
pmol/l
0.18
364
2971
510
3992
1.39
8.58
3.1
3.0
1531.15
1376.65
ng/l
0.32
441
3388
756
6304
1.36
8.56
7.4
6.0
1.21
1.21
mmol/l
0.05
708
5734
196
1267
1.62
8.49
2.4
2.0
336.59
372.66
nmol/l
1.91
186
1158
469
3628
1.40
8.43
3.2
2.7
5715.16
6361.71
umol/l
0.12
413
3169
163
1007
1.68
8.42
3.7
2.7
10.30
10.63
g/l
0.40
156
925
697
5754
1.36
8.37
2.4
2.2
76.37
76.94
nmol/l
0.22
649
5149
108
593
1.88
8.34
1.2
1.2
—
—
—
0
0
476
3701
1.40
8.28
5.0
3.9
0.00
0.01
estimate
1.28
178
1248
172
1095
1.63
7.92
4.9
4.2
0.02
0.12
%
3.38
54
345
651
5353
1.35
7.89
4.2
3.6
46.95
48.58
ng/l
0.05
456
3677
22
56
3.97
7.89
29.8
30.9
110.21
118.68
ug/l
0.27
17
47
178
1151
1.61
7.69
4.8
4.1
0.77
1.01
%
0.84
60
401
566
4570
1.36
7.69
3.4
3.2
30.33
33.65
u/l
1.59
541
4344
1396
12913
1.43
7.62
5.3
4.7
1.90
2.01
mu/l
0.58
1304
11818
224
1532
1.53
7.58
3.0
2.5
1.86
1.80
%
0.35
206
1361
473
3722
1.37
7.54
4.4
3.3
—
—
—
0
0
486
3843
1.37
7.51
4.2
3.1
0.54
0.50
e6/l
0.11
388
2937
371
2805
1.41
7.50
4.1
2.8
537.55
540.02
mosm/kgh2o
0.07
333
2422
174
1130
1.60
7.39
2.7
2.7
65.64
66.66
g/l
1.06
161
1031
512
4092
1.36
7.37
4.1
3.3
557.88
314.86
mg/l
0.47
348
2633
161
1028
1.62
7.33
5.0
4.3
0.05
0.68
%
0.87
39
282
254
1798
1.48
7.29
1.5
1.3
677.97
496.79
titre
0.62
59
374
535
4313
1.35
7.26
4.6
3.8
10.52
9.34
mg/mmol
0.20
372
2730
57
261
2.22
7.24
4.4
3.2
4.37
4.30
e9/l
0.09
57
261
60
281
2.18
7.22
4.0
2.5
16.09
16.13
%
0.02
28
147
391
3004
1.39
7.17
1.7
1.7
86405275.60
32705837.71
pmol/l
0.51
331
2495
1534
14494
1.54
7.12
22.3
16.3
3.98
3.97
mmol/l
0.84
1499
14088
267
1917
1.47
7.12
1.3
1.2
—
—
—
0
0
539
4368
1.34
7.01
4.2
3.2
7.48
7.52
mmol/l
0.07
468
3682
122
734
1.71
6.97
1.4
1.2
—
—
—
0
0
17
27
6.35
6.94
3.8
1.8
154.55
203.33
e6/l
0.32
11
12
234
1653
1.48
6.77
1.7
1.4
—
—
—
0
0
1528
14454
1.51
6.74
22.0
16.2
139.42
139.65
mmol/l
3.24
1498
14076
57
271
2.14
6.63
4.5
3.5
56.88
58.61
%
0.46
57
271
302
2247
1.42
6.63
3.6
3.3
0.82
0.82
mmol/l
0.34
289
2113
575
4742
1.32
6.53
3.7
3.5
2.34
2.35
mmol/l
0.88
516
4173
1571
14969
1.57
6.49
13.7
10.1
26.16
26.24
u/l
0.06
1526
14459
414
3257
1.36
6.47
1.6
1.5
20.78
20.67
nmol/l
0.04
381
2795
291
2162
1.42
6.43
2.3
2.0
29.64
29.72
s
0.08
285
2092
182
1238
1.53
6.31
9.6
7.3
11.29
9.75
mmol/l
1.80
175
1178
312
2355
1.40
6.28
1.3
1.3
37.56
31.11
iu/ml
0.28
104
754
168
1136
1.53
5.99
2.8
2.6
75.76
70.85
e9/l
1.03
132
872
220
1575
1.46
5.93
2.5
2.2
152.43
122.95
ug/g
0.46
175
1251
463
3748
1.32
5.90
4.3
3.1
—
—
—
0
0
346
2684
1.36
5.87
4.1
3.6
609.98
457.69
ng/l
0.23
264
2077
94
557
1.73
5.72
1.3
1.4
—
9.47
—
0
14
1449
13657
1.39
5.69
4.7
4.5
6.02
5.95
mmol/l
1.16
1335
12439
174
1201
1.50
5.64
5.3
3.8
—
—
—
0
0
176
1227
1.48
5.43
2.2
2.4
6.58
7.20
ug/l
0.16
148
1089
334
2610
1.35
5.36
3.5
3.1
2.45
2.45
mmol/l
0.07
292
2291
140
934
1.54
5.32
2.4
2.5
—
—
—
0
0
66
360
1.87
5.30
3.8
3.1
24.97
25.06
mmol/l
0.07
66
352
59
310
1.94
5.30
3.9
2.9
8.43
8.02
kpa
1.23
59
305
45
216
2.11
5.18
3.5
2.7
—
—
—
0
0
51
257
2.01
5.16
4.0
2.9
—
—
—
0
0
248
1861
1.39
5.13
7.6
5.5
1.05
1.03
mmol/l
0.56
229
1715
1030
9326
1.26
5.12
3.7
3.1
52.52
48.91
u/l
0.59
982
8698
333
2623
1.33
5.05
1.7
1.7
1206.97
1194.54
nmol/l
0.08
251
1975
25
93
2.71
5.01
1.2
1.1
—
—
—
0
0
1623
15691
1.62
4.99
29.0
20.5
6.85
6.77
e9/l
0.58
1588
15239
1302
12153
1.29
4.91
22.6
16.6
15.24
14.92
%
1.10
1283
11932
165
1160
1.47
4.90
8.0
8.8
—
—
—
0
0
1622
15687
1.60
4.88
28.9
20.5
91.29
91.03
fl
1.34
1606
15449
1622
15690
1.60
4.84
29.0
20.5
4.45
4.49
e12/l
1.86
1589
15235
301
2353
1.34
4.79
3.4
2.8
1.26
1.31
e6/l
0.07
174
1353
1621
15682
1.59
4.79
29.1
20.5
253.06
250.32
e9/l
0.87
1591
15277
1622
15695
1.59
4.77
29.2
20.6
133.98
135.18
g/l
2.64
1605
15459
290
2257
1.34
4.76
1.3
1.2
12.84
11.22
u/ml
0.12
105
874
69
397
1.77
4.70
3.2
2.2
2268.46
3065.17
u/l
0.22
25
178
1621
15689
1.58
4.69
28.9
20.4
30.33
30.31
pg
0.17
1605
15448
1372
12919
1.31
4.69
6.8
5.7
41.28
39.88
mmol/mol
3.83
1274
11960
56
303
1.88
4.65
5.7
4.5
2.26
2.75
mmol/l
0.67
38
199
56
304
1.87
4.60
5.7
4.5
4.92
5.04
kpa
0.61
56
298
56
304
1.87
4.60
5.7
4.5
8.70
8.51
kpa
0.41
56
298
121
809
1.53
4.58
3.0
3.3
4.46
4.53
pmol/l
0.26
112
717
160
1134
1.45
4.56
4.8
3.6
1.22
1.23
mmol/l
0.30
145
963
161
1146
1.45
4.49
3.9
2.9
167.51
196.60
ng/l
0.56
143
1043
1618
15672
1.55
4.44
29.0
20.7
39.68
40.07
%
1.46
1511
14658
1074
9861
1.24
4.32
4.3
3.8
—
—
—
0
0
137
960
1.46
4.16
1.5
1.4
—
—
—
0
0
177
1304
1.40
4.09
2.2
2.1
0.20
0.21
g/l
0.97
163
1219
202
1523
1.37
4.06
1.4
1.3
—
—
—
0
0
1460
13933
1.32
4.03
4.7
4.4
4.53
4.65
mmol/l
5.02
1359
12929
368
3023
1.28
4.03
4.5
4.0
1.02
1.02
kg/l
0.26
65
447
126
875
1.47
4.01
3.8
3.7
7.44
7.40
ph
1.88
21
108
39
197
2.00
3.99
1.6
2.2
—
4.80
—
0
5
147
1055
1.43
3.95
1.2
1.2
—
—
—
0
0
214
1637
1.35
3.93
7.4
7.8
1.37
1.19
mmol/l
0.32
170
1301
418
3505
1.25
3.83
8.4
6.4
—
—
—
0
0
384
3190
1.26
3.81
4.2
3.5
—
—
—
0
0
26
114
2.30
3.79
1.6
1.3
7.59
6.95
g/l
0.23
17
79
26
114
2.30
3.79
1.6
1.3
0.43
0.38
g/l
0.25
17
79
26
114
2.30
3.79
1.6
1.3
3.37
2.83
g/l
0.47
17
80
93
617
1.54
3.70
1.9
1.9
1.55
1.48
g/l
0.27
83
537
37
189
1.98
3.69
2.5
2.6
—
—
—
0
0
1480
14188
1.31
3.67
5.3
4.8
2.62
2.75
mmol/l
6.78
1370
13090
474
4049
1.24
3.66
4.8
3.8
—
—
—
0
0
26
117
2.24
3.58
1.6
1.3
—
—
—
0
0
1446
13837
1.28
3.51
4.6
4.3
1.45
1.46
mmol/l
0.53
1342
12759
211
1639
1.33
3.50
7.5
7.8
5.09
5.12
kpa
0.19
204
1568
35
179
1.98
3.49
3.9
2.5
—
—
—
0
0
211
1640
1.33
3.49
7.5
7.8
11.59
12.13
kpa
0.96
204
1571
176
1336
1.35
3.41
1.6
1.5
—
—
—
0
0
37
196
1.91
3.35
2.6
2.1
—
—
—
0
0
16
59
2.73
3.32
1.6
2.6
852.50
1458.24
u/ml
0.62
16
59
14
48
2.93
3.30
1.7
1.1
30.21
34.02
nmol/l
0.19
14
38
35
183
1.93
3.30
3.9
2.5
4.06
4.08
mmol/l
0.13
35
183
35
183
1.93
3.30
3.9
2.5
105.66
105.49
mmol/l
0.08
35
183
509
4423
1.21
3.27
4.9
4.9
2.35
2.68
ug/l
0.42
457
3957
634
5629
1.20
3.25
2.2
2.1
—
—
—
0
0
172
1317
1.34
3.16
3.5
2.3
36.19
78.21
u/l
0.60
145
1124
405
3456
1.22
3.10
2.7
2.3
—
—
—
0
0
37
202
1.85
3.08
1.9
1.7
1.61
0.84
g/l
0.51
26
154
24
112
2.16
3.07
1.4
1.2
—
—
—
0
0
1519
14677
1.30
3.06
18.3
13.3
—
—
—
0
0
44
255
1.74
3.03
2.1
1.4
—
—
—
0
0
11
31
3.56
2.99
2.9
3.2
—
—
—
0
0
431
3716
1.21
2.97
1.7
1.7
1.41
1.37
mmol/l
0.52
362
3123
517
4542
1.20
2.91
2.8
2.4
—
—
—
0
0
24
115
2.10
2.89
1.3
1.4
18.31
30.24
%
1.20
16
69
14
52
2.71
2.89
1.1
1.1
1489.87
1590.77
miu/ml
0.13
14
52
128
954
1.37
2.82
5.6
4.9
—
—
—
0
0
57
362
1.59
2.81
6.6
4.3
—
—
—
0
0
14
53
2.65
2.79
2.9
1.6
—
—
—
0
0
122
904
1.38
2.79
2.5
2.8
—
—
—
0
0
182
1433
1.30
2.77
3.5
4.3
5.69
20.26
ug/l
1.55
154
1189
198
1577
1.29
2.76
3.7
2.6
12.14
8.08
umol/l
0.86
178
1372
32
175
1.84
2.69
1.3
1.9
—
1666.67
—
0
6
8
19
4.23
2.68
1.5
1.2
—
—
—
0
0
8
19
4.23
2.68
1.5
1.2
—
—
—
0
0
8
19
4.23
2.68
1.5
1.2
—
—
—
0
0
735
6714
1.17
2.52
2.9
2.6
—
—
—
0
0
96
698
1.40
2.49
4.7
3.4
—
—
—
0
0
23
116
2.00
2.46
2.9
2.3
853.43
639.04
ml
2.60
14
78
407
3549
1.19
2.45
4.8
3.8
89.55
89.92
%
0.11
396
3461
26
138
1.90
2.41
1.1
1.3
—
—
—
0
0
286
2415
1.22
2.41
2.0
1.8
—
—
—
0
0
47
297
1.60
2.40
3.2
2.2
122.24
129.24
g/l
1.14
33
220
264
2214
1.23
2.38
3.7
2.9
3.34
2.63
e6/l
0.36
142
1222
75
526
1.45
2.38
2.0
1.9
21.46
21.36
s
0.06
65
469
36
214
1.70
2.33
1.9
1.4
—
—
—
0
0
1387
13359
1.20
2.30
4.3
3.9
1.33
1.29
mmol/l
1.01
1275
12215
18
85
2.13
2.29
3.2
2.2
511.00
496.78
min
0.36
11
64
215
1772
1.24
2.28
1.3
1.3
—
—
—
0
0
11
40
2.76
2.27
4.4
4.5
—
—
—
0
0
60
407
1.49
2.26
1.6
1.4
198.29
287.88
ug/g
3.06
37
239
101
755
1.36
2.24
10.0
10.8
—
—
—
0
0
55
368
1.51
2.22
1.1
1.1
—
—
—
0
0
16
73
2.20
2.21
1.2
1.4
1.06
1.23
nmol/l
0.19
11
57
25
136
1.85
2.18
1.9
1.6
—
—
—
0
0
1248
11932
1.17
2.18
25.0
17.9
331.82
332.38
g/l
1.44
1241
11841
6
14
4.30
2.15
1.7
1.3
54.67
47.64
umol/l
—
6
14
38
235
1.63
2.15
2.0
1.4
130.00
113.15
u/ml
—
8
39
87
641
1.38
2.12
3.3
3.9
—
—
—
0
0
9
31
2.91
2.07
1.8
1.5
—
—
—
0
0
45
293
1.55
2.07
6.9
3.8
—
—
—
0
0
119
926
1.31
2.03
1.2
1.2
98.39
137.10
iu/ml
0.67
41
364
25
140
1.80
2.01
2.3
2.1
28.70
8.30
umol/l
0.66
18
97
10
38
2.64
2.00
1.1
1.1
—
—
—
0
0
26
148
1.77
1.99
2.2
2.6
—
—
—
0
0
28
163
1.73
1.99
1.6
1.3
97.60
50.10
u/ml
—
5
8
51
345
1.49
1.98
1.5
1.2
14.99
9.24
u/ml
—
10
54
135
1075
1.28
1.95
4.7
3.7
102.27
88.30
ng/l
0.91
119
939
50
339
1.49
1.93
1.5
1.2
25.46
2.43
u/ml
—
9
30
11
45
2.45
1.93
2.6
1.6
—
—
—
0
0
15
71
2.12
1.92
2.5
3.3
7.42
7.41
ph
—
6
20
65
465
1.41
1.91
2.0
1.6
259.09
304.93
mu/l
0.85
58
416
17
85
2.01
1.90
3.0
2.9
45.30
39.08
%
—
10
45
59
415
1.44
1.90
3.6
3.6
40.62
66.95
mg/l
0.98
44
341
58
408
1.44
1.87
3.3
3.5
1.28
1.62
ratio
—
5
36
59
417
1.43
1.86
3.6
3.6
49.86
55.90
mg/l
0.12
44
343
16
79
2.03
1.85
1.1
1.0
—
—
—
0
0
39
254
1.55
1.82
1.5
1.2
265.30
251.87
u/ml
0.10
30
152
25
145
1.73
1.81
2.4
2.4
1.58
1.53
g/24h
0.03
14
72
55
387
1.44
1.78
2.1
1.7
37.87
39.51
nmol/l
0.19
55
371
53
372
1.44
1.75
1.1
1.1
7.02
6.14
u/ml
—
6
45
233
1994
1.19
1.74
1.8
1.6
—
—
—
0
0
8
30
2.67
1.72
2.8
3.1
—
36.64
—
0
7
7
24
2.92
1.72
1.4
1.1
—
—
—
0
0
44
299
1.48
1.71
3.8
3.8
—
—
—
0
0
60
436
1.39
1.65
1.1
1.1
—
—
—
0
0
15
76
1.98
1.64
1.1
1.0
—
—
—
0
0
18
98
1.85
1.62
1.3
1.4
88.33
84.13
umol/l
0.10
18
98
5
14
3.58
1.61
1.0
3.0
—
—
—
0
0
57
413
1.39
1.60
1.2
1.2
—
—
—
0
0
49
348
1.42
1.54
3.1
2.3
205.99
108.47
ug/min
0.76
27
220
140
1156
1.23
1.52
4.3
3.3
—
—
—
0
0
5
15
3.34
1.52
1.4
1.0
0.03
0.07
u/ml
—
5
15
5
15
3.34
1.52
4.6
2.5
—
—
—
0
0
62
461
1.36
1.50
2.7
1.8
—
—
—
0
0
143
1714
0.82
1.50
5.1
4.5
33.74
32.35
%
0.86
110
1160
144
1196
1.22
1.49
1.8
1.6
—
—
—
0
0
38
259
1.48
1.49
1.4
1.3
—
—
—
0
0
36
243
1.49
1.48
1.5
1.6
—
—
—
0
0
69
524
1.33
1.47
4.4
4.0
1.49
1.42
mmol/l
0.13
69
517
19
109
1.75
1.47
2.1
1.2
4.34
0.78
u/ml
0.89
14
61
75
577
1.31
1.46
5.5
4.7
—
—
—
0
0
58
430
1.36
1.44
2.7
1.9
—
—
—
0
0
5
16
3.13
1.44
1.6
1.4
81.00
95.88
ng/l
—
5
16
55
405
1.37
1.43
1.3
1.2
—
—
—
0
0
45
320
1.42
1.43
1.8
1.7
26383.89
13891.71
e6/l
0.39
36
234
122
1001
1.24
1.42
1.5
1.4
—
—
—
0
0
35
237
1.49
1.42
5.6
3.0
—
—
—
0
0
62
467
1.34
1.40
2.7
1.9
—
—
—
0
0
72
555
1.31
1.39
2.7
2.7
—
—
—
0
0
34
230
1.49
1.39
1.9
1.4
—
—
—
0
0
62
468
1.34
1.38
2.7
1.9
—
—
—
0
0
12
60
2.01
1.38
1.2
3.3
67.50
121.40
umol/l
—
6
35
25
158
1.59
1.38
1.4
1.3
—
—
nmol/l
—
0
0
66
853
0.76
1.35
1.4
1.4
—
—
—
0
0
62
471
1.33
1.34
2.8
1.9
—
—
—
0
0
180
1545
1.18
1.33
1.8
1.6
—
—
—
0
0
31
208
1.50
1.33
3.4
2.4
—
—
—
0
0
6
24
2.51
1.30
1.3
1.8
—
—
—
0
0
10
48
2.09
1.27
1.0
1.1
—
—
—
0
0
39
277
1.42
1.27
1.9
1.7
—
—
—
0
0
9
45
2.01
1.23
1.0
1.1
—
—
—
0
0
76
602
1.27
1.23
1.9
1.9
—
—
—
0
0
10
49
2.05
1.22
1.5
2.1
7337.80
35338.81
e6/l
—
5
32
123
1030
1.21
1.21
2.5
2.2
12.63
12.56
nmol/l
0.03
111
928
88
711
1.25
1.21
2.5
2.4
—
—
—
0
0
6
26
2.31
1.18
1.2
1.8
—
—
—
0
0
38
274
1.40
1.16
2.4
1.8
159.68
208.59
pmol/l
2.09
38
257
8
39
2.06
1.15
2.6
2.1
3.38
5.97
%
—
8
39
8
39
2.06
1.15
2.6
2.1
—
—
—
0
0
8
39
2.06
1.15
2.4
1.5
—
—
—
0
0
46
343
1.35
1.15
2.0
1.9
2.73
4.96
iu/l
2.73
15
120
17
104
1.64
1.09
1.1
1.2
—
—
—
0
0
22
144
1.53
1.09
3.9
3.4
—
—
—
0
0
10
52
1.93
1.06
2.9
2.6
—
—
—
0
0
18
113
1.60
1.05
1.1
1.1
—
—
—
0
0
12
67
1.80
1.04
1.7
1.4
—
—
—
0
0
9
46
1.96
1.03
1.4
2.0
—
—
—
0
0
9
46
1.96
1.03
1.0
1.0
—
—
—
0
0
25
171
1.47
1.02
1.4
1.4
—
—
—
0
0
5
23
2.18
0.98
2.6
5.7
—
—
—
0
0
284
2582
1.12
0.98
2.8
3.0
0.80
0.76
ug/l
0.25
181
1677
99
833
1.20
0.97
1.1
1.3
—
52.00
—
0
50
23
157
1.47
0.96
1.3
1.3
—
—
—
0
0
142
1235
1.16
0.95
1.5
1.4
—
—
—
0
0
13
78
1.67
0.91
2.0
2.6
—
—
—
0
0
22
151
1.46
0.90
3.0
4.3
—
—
—
0
0
38
289
1.32
0.88
4.0
1.8
0.75
0.85
nmol/l
0.54
32
237
23
161
1.43
0.86
1.5
1.3
278.61
278.86
mosm/kgh2o
0.02
18
121
21
145
1.45
0.85
1.4
2.1
—
—
—
0
0
47
372
1.27
0.83
3.2
1.8
—
—
—
0
0
6
33
1.82
0.79
1.5
1.2
—
—
—
0
0
11
66
1.67
0.78
2.7
2.9
—
—
—
0
0
18
258
0.69
0.78
1.8
1.5
—
—
—
0
0
53
430
1.24
0.77
3.2
3.2
—
—
—
0
0
60
494
1.22
0.77
2.8
3.3
0.80
0.27
g/l
0.79
27
203
20
140
1.43
0.77
1.2
1.1
—
—
—
0
0
6
34
1.77
0.76
1.2
1.7
119.67
95.62
nmol/24h
—
6
34
7
38
1.85
0.73
1.7
1.7
—
—
—
0
0
29
219
1.33
0.73
1.2
1.1
—
—
—
0
0
26
193
1.35
0.73
1.0
1.0
5.27
1.68
u/ml
0.76
11
82
136
1210
1.13
0.71
1.6
1.4
—
—
—
0
0
18
252
0.71
0.70
1.7
1.4
—
—
—
0
0
26
343
0.75
0.70
1.3
1.3
—
—
—
0
0
7
41
1.71
0.70
1.7
1.5
—
—
—
0
0
18
251
0.71
0.69
1.7
1.4
—
—
—
0
0
10
61
1.64
0.68
3.8
2.4
69.90
48.86
umol/l
—
10
49
32
250
1.29
0.66
1.3
1.2
—
—
—
0
0
18
128
1.41
0.65
1.2
1.1
—
—
—
0
0
29
225
1.29
0.63
1.8
1.6
—
—
—
0
0
21
155
1.36
0.63
1.4
1.7
63.07
59.37
%
0.18
14
101
10
63
1.59
0.61
1.2
1.1
144.09
201.89
iu/ml
—
10
63
8
50
1.60
0.61
1.4
1.2
—
—
—
0
0
54
453
1.20
0.61
10.3
9.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
1.79
—
0
22
523
5004
1.06
0.58
3.3
2.8
—
—
—
0
0
152
1384
1.11
0.57
4.6
4.5
—
—
—
0
0
101
900
1.13
0.55
1.2
1.2
—
—
—
0
0
61
525
1.17
0.54
3.9
3.5
66.32
2547.57
u/ml
0.73
53
454
25
196
1.28
0.52
1.0
1.1
2.14
1.91
u/ml
0.11
17
93
25
198
1.27
0.49
1.2
1.2
—
—
—
0
0
7
45
1.56
0.49
1.1
1.2
—
—
—
0
0
11
77
1.43
0.45
2.3
1.6
—
—
—
0
0
26
210
1.24
0.45
1.0
1.1
8.39
6.17
u/ml
0.22
17
104
15
112
1.34
0.44
2.3
2.2
1.29
2.20
u/field
—
7
50
405
3880
1.06
0.44
1.5
1.4
—
—
—
0
0
103
939
1.10
0.41
4.6
2.9
5.25
5.90
e9/l
0.16
88
765
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
36
305
1.18
0.41
2.4
2.6
—
—
—
0
0
26
213
1.22
0.41
1.4
1.5
—
—
—
0
0
5
34
1.47
0.40
2.8
1.7
—
—
—
0
0
19
152
1.25
0.37
1.8
1.4
—
—
—
0
0
6
42
1.43
0.35
1.3
2.1
—
—
—
0
0
10
73
1.37
0.34
1.1
1.3
154.91
143.48
nmol/l
—
10
73
28
238
1.18
0.32
1.2
1.1
9.54
2.30
u/ml
1.04
19
121
43
379
1.14
0.32
1.2
1.2
—
—
—
0
0
7
53
1.32
0.31
2.6
2.0
12.06
182.87
ug/l
—
7
43
10
75
1.34
0.30
1.8
2.5
2179.00
1935.46
ml
—
10
65
10
75
1.34
0.30
1.1
1.2
—
—
—
0
0
33
287
1.15
0.30
1.4
1.6
—
—
—
0
0
11
84
1.31
0.30
4.8
4.0
—
—
—
0
0
7
55
1.27
0.30
14.1
16.1
—
—
—
0
0
24
203
1.18
0.30
1.0
1.1
4.99
1.60
u/ml
0.42
12
81
7
56
1.25
0.29
1.1
1.2
—
0.12
g/l
—
0
5
18
148
1.22
0.29
1.8
1.4
—
—
—
0
0
8
107
0.75
0.29
1.1
1.0
325.63
287.34
mg/l
—
8
94
36
317
1.14
0.28
1.6
1.6
1532.28
742.92
e6/l
0.36
29
256
36
317
1.14
0.28
1.4
1.5
5.79
7.56
e6/l
0.26
29
246
11
85
1.30
0.28
6.6
6.9
—
—
—
0
0
8
63
1.27
0.27
1.1
1.1
—
10.43
—
0
7
27
234
1.16
0.26
1.7
1.2
—
—
—
0
0
35
310
1.13
0.26
5.7
3.6
28.38
25.60
mg/l
0.16
28
200
9
75
1.20
0.25
3.0
2.9
—
—
—
0
0
54
493
1.10
0.24
1.7
1.6
—
—
—
0
0
19
161
1.18
0.24
1.6
1.8
—
—
—
0
0
19
161
1.18
0.24
1.0
1.1
9.70
3.43
u/ml
—
9
63
41
370
1.11
0.23
1.6
1.3
9.95
9.32
u/l
0.10
34
296
17
143
1.19
0.23
1.6
1.8
—
—
—
0
0
67
722
0.93
0.23
1.7
1.7
—
—
—
0
0
13
157
0.83
0.22
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.21
—
0
5
0
10
0.00
0.21
0.0
2.8
—
48.36
—
0
10
0
12
0.00
0.21
0.0
1.0
—
12.20
—
0
5
11
89
1.24
0.21
3.7
2.3
—
—
—
0
0
6
53
1.13
0.18
1.5
3.2
—
—
—
0
0
13
109
1.19
0.18
1.4
1.1
416.00
155.00
titre
—
5
18
25
225
1.11
0.16
1.3
1.1
—
—
—
0
0
25
225
1.11
0.16
1.3
1.1
—
—
—
0
0
38
351
1.08
0.15
2.0
2.5
—
—
—
0
0
9
81
1.11
0.15
12.9
12.0
0.85
0.63
mmol/l
—
9
74
7
88
0.79
0.14
1.0
1.0
—
—
—
0
0
131
1265
1.04
0.14
1.4
1.4
—
—
—
0
0
24
218
1.10
0.13
1.3
1.2
—
—
—
0
0
5
44
1.14
0.10
1.2
1.9
—
—
—
0
0
22
203
1.08
0.09
1.3
1.2
2.13
4.56
u/ml
—
8
88
29
308
0.94
0.08
1.1
1.4
108.49
195.75
pmol/l
0.87
29
303
5
62
0.81
0.08
1.0
1.3
185.00
170.28
mmol/24h
—
5
62
5
63
0.79
0.08
1.2
1.7
—
—
—
0
0
11
123
0.89
0.08
1.6
3.3
9.80
31.20
mg/l
—
6
92
7
66
1.06
0.08
1.0
1.2
—
—
—
0
0
8
75
1.07
0.07
2.9
1.8
0.88
2.92
u/field
—
8
57
160
1571
1.02
0.07
1.7
1.7
—
—
—
0
0
16
173
0.92
0.06
1.5
1.4
1231.91
1684.86
e6/l
0.35
11
120
14
128
1.09
0.06
1.2
1.3
—
—
—
0
0
24
226
1.06
0.06
1.0
1.0
—
—
—
0
0
15
138
1.09
0.06
1.3
2.3
—
—
—
0
0
58
563
1.03
0.05
1.1
1.1
—
—
—
0
0
11
120
0.92
0.05
1.0
1.1
—
—
—
0
0
60
585
1.03
0.04
1.6
1.3
24.09
28.14
iu/l
0.52
50
495
31
298
1.04
0.04
3.7
2.6
—
—
—
0
0
41
399
1.03
0.03
1.1
1.3
172.91
242.65
miu/ml
0.67
13
189
10
108
0.93
0.03
3.7
2.2
10.82
10.89
%
—
10
108
12
113
1.06
0.02
1.8
1.6
0.98
0.97
g/l
0.03
12
113
14
147
0.95
0.01
1.8
1.6
—
—
—
0
0
10
94
1.06
0.01
1.3
1.2
29.00
13.82
u/l
—
10
88
16
154
1.04
0.00
1.6
1.2
—
—
—
0
0
14
145
0.97
0.00
1.0
1.2
—
—
—
0
0
16
155
1.03
0.00
1.5
1.4
19035.56
82116.89
e6/l
—
9
93
10
101
0.99
0.00
1.6
1.4
—
—
—
0
0
15
149
1.01
0.00
1.6
1.5
—
—
—
0
0
10
96
1.04
0.00
1.1
1.2
—
—
—
0
0
25
254
0.98
0.00
1.4
1.8
—
—
—
0
0
27
266
1.02
0.00
1.3
1.2
—
—
—
0
0
17
172
0.99
0.00
1.2
1.4
6.54
7.47
mmol/l
0.90
12
148
15
148
1.01
0.00
3.4
2.6
—
—
—
0
0
14
137
1.02
0.00
1.6
1.4
—
—
—
0
0
18
177
1.02
0.00
1.1
1.1
13.18
2.69
u/ml
—
10
86
24
237
1.01
0.00
3.0
3.8
25.88
25.48
u/ml
0.02
24
230
31
307
1.01
0.00
2.7
3.2
0.74
0.82
nmol/l
0.46
20
240
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.90
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.06
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
-0.00
1.5
1.5
—
—
—
0
0
9
96
0.94
-0.00
1.3
1.4
167.78
155.52
pmol/l
—
9
96
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.6
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
13.76
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
92
0.98
-0.00
1.0
1.4
1.57
1.54
g/l
—
9
92
8
79
1.01
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
327.29
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
78
0.90
-0.00
1.3
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
1.81
—
0
8

Mortality – FinRegistry

Association

Association between endpoint H7_HERPESKERATITIS and mortality.

Females

Parameter HR [95% CI] p-value
H7_HERPESKERATITIS 1.265 [1.13, 1.41] < 0.001
Birth year 0.996 [0.99, 1.0] 0.337

During the follow-up period (1.1.1998 — 31.12.2019), 1095 out of 6103 females with H7_HERPESKERATITIS died.

Males

Parameter HR [95% CI] p-value
H7_HERPESKERATITIS 1.22 [1.09, 1.37] < 0.001
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 1073 out of 5181 males with H7_HERPESKERATITIS died.

Mortality risk

Mortality risk for people of age

years, who have H7_HERPESKERATITIS.

N-year risk Females Males
1 0.162% 0.24%
5 0.728% 1.368%
10 1.919% 3.58%
15 3.975% 6.901%
20 6.792% 11.807%

Relationships between endpoints

Index endpoint: H7_HERPESKERATITIS – Herpesviral keratitis and keratoconjunctivitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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