No definition available.
Medullary carcinoma of thyroid gland, including Hilmo
C3_THYROID_MEDULLARY_WIDE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
75 |
4. Check minimum number of eventsNone |
75 |
5. Include endpointsNone |
75 |
6. Filter based on genotype QC (FinnGen only) |
74 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Medullary carcinoma of thyroid gland, including Hilmo
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of thyroid gland, including Hilmo
- Malignant neoplasm, wide definition for exclusion
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 74 | 54 | 20 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 49.02 | 46.25 | 56.50 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 75
- Matched controls
- 750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C73.94
ICD-10 Finland
Medullary thyroid carcinoma (thyroid)
+∞
95.5
70
*
104
Kela drug reimbursment
Thyroid insufficiency
71.8
79.0
58
34
H03AA01
ATC
levothyroxine sodium; systemic
83.3
42.4
71
131
8345/3-C73.9
ICD-O-3
Medullary thyroid carcinoma of thyroid gland
+∞
37.7
33
*
8510/3-C73.9
ICD-O-3
Medullary carcinoma, NOS, of thyroid gland
+∞
36.4
32
*
BAA60
NOMESCO Finland
Total thyroidectomy
67.3
36.4
41
13
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
84.1
33.5
36
8
EP1AE
NOMESCO Finland
Neck ultrasound examination
62.2
33.4
38
12
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
24.3
22
*
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
+∞
23.1
21
*
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
+∞
21.9
20
*
130
Kela drug reimbursment
Malignant tumour
+∞
20.8
19
*
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
+∞
20.8
19
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
19.6
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.3
14.1
36
96
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
+∞
12.9
12
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
12.9
12
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
11.8
11
*
JN4BD
NOMESCO Finland
Extensive body CT
17.8
11.7
18
13
WZC00
NOMESCO Finland
Treatment plan or consultation
4.7
10.1
37
128
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
35.1
9.7
12
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
113.8
9.7
10
*
N02AA05
ATC
oxycodone; systemic
5.7
9.6
22
51
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
+∞
9.6
9
*
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
+∞
9.6
9
*
T71
ICPC
Malignant neoplasm thyroid
+∞
9.6
9
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
9.6
9
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.3
8.7
21
51
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
+∞
8.5
8
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
+∞
8.5
8
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
37.9
8.3
10
*
Z51.5
ICD-10 Finland
Palliative care
50.4
7.9
9
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.9
7.9
40
170
A11CC03
ATC
alfacalcidol; systemic
28.4
7.8
10
*
WZC30
NOMESCO Finland
Teaching
5.3
7.7
18
42
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
+∞
7.4
7
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
+∞
7.4
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.4
7
*
C739, ,
ICD-10 Finland
+∞
7.4
7
*
JN6AD
NOMESCO Finland
CT of torso and neck
33.6
7.3
9
*
Z31.5
ICD-10 Finland
Genetic counselling
11.0
7.1
13
14
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
18.9
7.0
10
6
XX3DW
NOMESCO Finland
Time consuming IT work
9.6
6.7
13
16
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
76.0
6.5
7
*
WX402
NOMESCO Finland
General anaesthesia
4.0
6.4
22
70
C73.93
ICD-10 Finland
Anaplastic thyroid carcinoma (thyroid)
+∞
6.3
6
*
1930D
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA MEDULLARE THYREOIDEAE]
+∞
6.3
6
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
+∞
6.3
6
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
6.3
6
*
H01CB03
ATC
lanreotide; parenteral
+∞
6.3
6
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
5
82.63
25.08
5.0
1.2
16.77
—
u/ml
—
7
0
22
5
60.93
19.51
1.8
1.0
—
—
—
0
0
65
244
13.48
19.08
11.5
4.3
1.21
1.22
mmol/l
0.84
65
220
22
69
4.10
6.50
5.2
1.8
0.83
0.84
mmol/l
0.24
22
62
48
254
3.47
6.33
3.0
2.3
—
—
—
0
0
27
124
2.84
4.20
2.8
1.6
—
—
—
0
0
42
250
2.55
3.82
17.2
11.5
1.22
1.27
inr
0.12
13
78
50
341
2.40
3.15
8.2
5.6
3.52
4.24
e9/l
1.87
45
299
45
294
2.33
3.12
10.4
3.3
10.15
10.72
umol/l
0.32
45
274
15
58
2.98
3.10
3.1
4.1
1.04
1.03
mmol/l
0.03
15
52
8
17
5.13
3.01
1.9
1.8
166.90
2.95
ug/l
—
8
17
14
57
2.79
2.63
1.9
1.6
492.86
409.23
nmol/l
0.20
14
52
11
43
2.82
2.19
4.9
6.0
125.36
127.51
g/l
0.13
11
43
7
20
3.75
2.11
1.9
6.6
26.81
24.87
mmol/l
—
7
20
7
21
3.56
2.02
8.1
3.6
2.69
1.36
mmol/l
—
7
16
69
605
2.75
1.91
18.8
9.4
86.97
81.66
ml/min/173m2
1.16
62
474
11
48
2.51
1.80
4.5
5.6
105.09
104.92
mmol/l
0.05
11
48
6
22
2.87
1.46
1.3
1.7
0.87
0.90
%
—
6
22
9
41
2.35
1.43
4.6
3.1
—
—
—
0
0
7
34
2.17
1.06
2.4
1.4
—
—
—
0
0
0
29
0.00
1.00
0.0
1.4
—
—
—
0
0
0
31
0.00
0.99
0.0
1.5
—
—
—
0
0
6
28
2.24
0.94
6.0
7.8
0.48
0.71
%
—
6
28
10
56
1.91
0.93
2.0
1.6
—
—
—
0
0
10
57
1.87
0.88
2.0
1.6
—
—
—
0
0
0
25
0.00
0.80
0.0
1.2
—
—
—
0
0
9
53
1.79
0.79
1.7
1.9
28.67
30.41
u/l
—
9
41
12
79
1.62
0.67
2.1
1.6
—
—
—
0
0
5
28
1.84
0.67
6.8
7.9
1.26
1.65
%
—
5
28
59
536
1.47
0.63
21.9
12.2
13.54
14.71
%
3.92
59
530
11
72
1.62
0.63
3.5
2.1
5.25
4.90
umol/l
0.18
11
60
20
242
0.76
0.41
2.9
3.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
67
643
1.39
0.31
17.4
10.6
28.17
20.53
mg/l
0.99
54
473
15
121
1.30
0.31
1.1
1.4
—
—
—
0
0
28
314
0.83
0.28
2.8
3.4
0.00
0.00
estimate
—
5
56
9
72
1.28
0.27
1.7
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
3.0
—
13.97
—
0
11
0
11
0.00
0.21
0.0
1.2
—
8.60
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
94.40
—
0
5
0
12
0.00
0.21
0.0
1.8
—
95.75
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
29
316
0.87
0.19
2.8
3.5
0.00
0.00
estimate
—
5
44
10
119
0.82
0.17
1.4
1.4
—
—
—
0
0
6
78
0.75
0.16
11.5
5.8
—
—
—
0
0
11
95
1.19
0.12
4.3
3.3
23.78
23.02
%
—
6
40
41
393
1.10
0.10
2.6
3.0
—
—
—
0
0
5
60
0.82
0.08
2.2
2.4
—
—
—
0
0
23
241
0.93
0.05
1.7
1.8
87.02
104.27
pmol/l
0.93
12
111
19
192
0.99
0.00
2.3
2.9
—
—
—
0
0
25
245
1.03
0.00
3.9
3.2
20.27
51.51
ng/l
1.21
20
167
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
66
0.90
-0.00
2.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
70
1.00
-0.00
2.0
1.5
1.21
1.48
%
—
7
63
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
58.43
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
5.82
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
2.52
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_THYROID_MEDULLARY_WIDE – Medullary carcinoma of thyroid gland, including Hilmo
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).