No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1037 |
4. Check minimum number of eventsNone |
1037 |
5. Include endpointsNone |
1037 |
6. Filter based on genotype QC (FinnGen only) |
990 |
Control definitions (FinnGen only)
- Control exclude
- H7_SCLERACORNEA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H15-H22
- Name in latin
- Cicatrices et opacitates corneae
Similar endpoints
↥List of similar endpoints to
Corneal scars and opacities
based on the number of shared cases.
Similar with more cases:
- Keratitis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7698 | 3908 | 3727 |
| Only index persons | 6810 | 3444 | 3366 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.11 | 0.10 |
| Only index persons | 0.13 | 0.13 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 61.16 | 67.07 | 54.84 |
| Only index persons | 59.45 | 65.16 | 53.60 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 990 | 523 | 467 |
| Unadjusted period prevalence (%) | 0.20 | 0.19 | 0.21 |
| Median age at first event (years) | 61.03 | 60.80 | 61.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1037
- Matched controls
- 10370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H17.1
ICD-10 Finland
Other central corneal opacity
+∞
307.7
310
*
H16.0
ICD-10 Finland
Corneal ulcer
55.3
307.7
265
64
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
+∞
307.7
322
*
H17.8
ICD-10 Finland
Other corneal scars and opacities
6185.8
307.7
404
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
123.7
256.3
130
12
S01AD03
ATC
aciclovir; ophthalmic
17.0
177.7
155
106
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
6.5
176.2
755
3033
H16.9
ICD-10 Finland
Keratitis, unspecified
280.5
145.2
145
6
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.5
141.6
282
565
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.0
114.5
316
834
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
109.3
103
*
CG2S4
NOMESCO Finland
Photography of cornea
304.7
109.2
109
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
168.4
102.3
106
7
H04.10
ICD-10 Finland
Dry eye syndrome
5.4
102.2
237
536
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
225.9
100.4
102
5
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.7
96.3
552
2417
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
982.9
93.4
90
*
XCK10
NOMESCO Finland
Photography of fundus of eye
5.1
90.6
221
519
H17.0
ICD-10 Finland
Adherent leukoma
+∞
77.0
73
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.2
76.0
242
695
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
+∞
72.8
69
*
H18.4
ICD-10 Finland
Corneal degeneration
736.5
71.0
69
*
S01ED01
ATC
timolol; ophthalmic
8.2
69.4
96
127
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
23.8
69.1
50
22
H18.8
ICD-10 Finland
Other specified disorders of cornea
360.0
68.4
68
*
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
+∞
67.4
64
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
103.9
62.7
68
7
WX140
NOMESCO Finland
Parabulbar anesthesy
6.0
61.1
115
211
CD2S4
NOMESCO Finland
Photography of eye
21.3
59.5
45
22
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.1
58.9
186
525
S01BA07
ATC
fluorometholone; ophthalmic
13.8
57.4
54
41
Z3229
NOMESCO Finland
Other healthcare associate professional
4.2
56.3
169
459
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
51.0
277
1100
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
73.8
49.6
56
8
H16.2
ICD-10 Finland
Keratoconjunctivitis
128.4
46.2
49
*
S01ED51
ATC
timolol, combinations; ophthalmic
4.1
46.2
139
376
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.5
45.2
431
2263
3710A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Corneal scars and opacities
+∞
44.1
42
*
ZXA10
NOMESCO Finland
Bilateral
2.8
43.7
277
1186
S01BC03
ATC
diclofenac; ophthalmic
8.2
42.1
57
73
S01BA04
ATC
prednisolone; ophthalmic
9.3
41.0
50
56
S01EA05
ATC
brimonidine; ophthalmic
7.2
40.7
62
91
H25.1
ICD-10 Finland
Senile nuclear cataract
2.5
39.8
369
1891
H11.0
ICD-10 Finland
Pterygium
13.9
37.5
35
26
H52.2
ICD-10 Finland
Astigmatism
7.4
35.9
53
75
H26.2
ICD-10 Finland
Complicated cataract
11.6
35.5
37
33
L04AA01
ATC
[U] ciclosporin
12.5
35.2
35
29
H16.8
ICD-10 Finland
Other keratitis
180.9
33.9
35
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
124.2
33.9
36
*
S01BA01
ATC
dexamethasone; ophthalmic
5.4
33.6
69
136
H20.1
ICD-10 Finland
Chronic iridocyclitis
+∞
33.5
32
*
H18.6
ICD-10 Finland
Keratoconus
326.7
32.0
32
*
S01EC01
ATC
acetazolamide; systemic
6.7
30.5
49
76
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.2
30.4
131
446
H17
ICD-10 Finland
Corneal scars and opacities
+∞
30.4
29
*
WX002
NOMESCO Finland
Sedation and analgesia
2.4
29.5
255
1242
XCK00
NOMESCO Finland
Perimetry
3.6
28.3
99
295
CGE10
NOMESCO Finland
Keratectomy
+∞
28.3
27
*
CFD10
NOMESCO Finland
Repair of conjunctiva
65.9
28.1
32
5
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.6
28.0
99
297
S01EE01
ATC
latanoprost; ophthalmic
3.5
27.3
101
312
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
27.2
26
*
H18.1
ICD-10 Finland
Bullous keratopathy
278.0
26.8
27
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.5
26.3
97
299
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
+∞
26.2
25
*
3604
FHL
Penetration of the cornea
+∞
26.2
25
*
H27.0
ICD-10 Finland
Aphakia
31.9
26.0
34
11
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.6
26.0
90
266
ZXA00
NOMESCO Finland
Right side
2.1
25.7
328
1859
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
138.5
25.7
27
*
T15.0
ICD-10 Finland
Foreign body in cornea
4.6
25.5
62
141
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
25.1
24
*
H57.1
ICD-10 Finland
Ocular pain
4.8
24.8
57
124
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
256.0
24.8
25
*
H26.4
ICD-10 Finland
After-cataract
2.7
23.8
138
552
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4.7
23.1
54
119
S01AA01
ATC
chloramphenicol; ophthalmic
3.7
23.1
76
217
Z3231
NOMESCO Finland
Registered nurse
2.0
22.3
320
1879
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.4
22.0
83
259
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
224.5
21.7
22
*
S01XA18
ATC
ciclosporin; ophthalmic
21.3
21.3
31
15
H02.1
ICD-10 Finland
Ectropion of eyelid
9.2
21.3
26
29
CGF10
NOMESCO Finland
Suture of laceration of cornea
+∞
20.9
20
*
H16.3
ICD-10 Finland
Interstitial and deep keratitis
+∞
20.9
20
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
20.8
417
2728
ZXE00
NOMESCO Finland
One hour or less
1.9
20.7
424
2789
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
112.3
20.6
22
*
114
Kela drug reimbursment
Glaucoma
2.7
20.2
119
478
J05AB11
ATC
valaciclovir; oral
2.3
20.1
176
850
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
8.1
20.1
27
34
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
+∞
19.9
19
*
ZXA05
NOMESCO Finland
Left side
2.0
19.8
288
1688
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
8.5
19.3
25
30
XCH00
NOMESCO Finland
Eye pressure measurement
3.4
18.5
68
209
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
4.9
18.3
41
87
127
Kela drug reimbursment
Transplant complication
6.2
18.2
31
51
J05AB01
ATC
aciclovir; systemic
2.0
18.0
241
1367
H01.0
ICD-10 Finland
Blepharitis
2.9
17.7
87
317
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
96.7
17.6
19
*
S01GX01
ATC
cromoglicic acid; ophthalmic
2.0
17.5
217
1196
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
15.1
17.2
28
19
S01FA04
ATC
cyclopentolate; ophthalmic
16.3
17.1
27
17
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
5.6
16.7
32
59
H18.9
ICD-10 Finland
Disorder of cornea, unspecified
+∞
16.7
16
*
CGF35
NOMESCO Finland
Repair of cornea using graft
+∞
16.7
16
*
H18.2
ICD-10 Finland
Other corneal oedema
+∞
16.7
16
*
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
4.8
16.4
37
79
L01BA01
ATC
methotrexate; systemic
3.9
16.4
48
126
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.8
16.4
85
319
S01BC05
ATC
ketorolac; ophthalmic
3.5
16.2
57
170
ZXD20
NOMESCO Finland
Day surgery
2.2
15.9
154
771
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
15.7
15
*
CBH30
NOMESCO Finland
Tarsorraphy
+∞
15.7
15
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
4.6
15.5
37
83
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
6.8
15.3
24
36
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
45.7
15.1
18
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
32.2
14.8
19
6
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
14.6
14
*
F01
ICPC
Eye pain
4.2
14.6
39
96
H10.4
ICD-10 Finland
Chronic conjunctivitis
6.7
14.5
23
35
B00.5
ICD-10 Finland
Herpesviral ocular disease
36.6
14.5
18
5
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
14.5
145
735
S01AX11
ATC
[U] ofloxacin
3.5
14.4
50
148
Z2221
NOMESCO Finland
Medical doctor
1.8
14.2
287
1840
H02.2
ICD-10 Finland
Lagophthalmos
17.8
13.9
21
12
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
11.6
13.8
25
22
CGE16
NOMESCO Finland
Destruction of lesion of cornea
+∞
13.6
13
*
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
+∞
13.6
13
*
37100
ICD-8 Finland
Corneal opacity, Cicatrix (nubecula, macula, leucoma) cornea
+∞
13.6
13
*
H20.8
ICD-10 Finland
Other iridocyclitis
141.8
13.5
14
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
13.4
273
1749
H40.0
ICD-10 Finland
Glaucoma suspect
2.4
13.4
94
410
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
13.3
375
2626
S01EA03
ATC
apraclonidine; ophthalmic
9.8
13.3
26
27
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
28.8
13.0
17
6
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
50.7
12.9
15
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.0
12.8
36
92
H02AB06
ATC
prednisolone; systemic
1.6
12.8
476
3564
3619
FHL
Other operations in this group, such as corneal refractive surgery
+∞
12.5
12
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.3
12.5
32
76
H52.1
ICD-10 Finland
Myopia
3.5
12.3
43
128
CGC10
NOMESCO Finland
Removal of foreign body from cornea
12.6
12.1
21
17
R4110
NOMESCO Finland
Physiotherapy
1.7
12.0
286
1905
CKD60
NOMESCO Finland
Anterior vitrectomy
9.8
11.8
23
24
S01EC04
ATC
brinzolamide; ophthalmic
3.0
11.8
52
179
H15.1
ICD-10 Finland
Episcleritis
16.6
11.7
18
11
S01FA02
ATC
scopolamine; ophthalmic
16.6
11.7
18
11
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
11.5
150
833
H18.7
ICD-10 Finland
Other corneal deformities
+∞
11.5
11
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
4.2
11.4
30
73
S01EC03
ATC
dorzolamide; ophthalmic
5.1
11.0
23
46
L28
ICPC
Limited function/disability (L)
1.8
10.9
186
1124
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
10.9
85
388
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
60.6
10.6
12
*
J01DB01
ATC
cefalexin; oral
1.7
10.5
826
7232
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
111.1
10.4
11
*
CGW99
NOMESCO Finland
Other operation on cornea or sclera
+∞
10.4
10
*
C01BD01
ATC
amiodarone; systemic
3.3
10.4
39
122
WX142
NOMESCO Finland
Sub-tenon anesthesy
9.7
10.3
20
21
CGE55
NOMESCO Finland
Excision of pterygium with transplanation of conjunctiva
19.0
10.3
15
8
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.8
10.3
23
49
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.7
10.1
32
89
S01EC54
ATC
brinzolamide, combinations; ophthalmic
5.3
10.1
20
38
H25.0
ICD-10 Finland
Senile incipient cataract
2.4
10.1
72
316
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
10.0
461
3561
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
10.0
693
5847
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.1
9.9
100
507
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
5.0
9.8
21
43
S01EX03, ,
ATC
3.7
9.8
30
82
F29
ICPC
Eye symptom/complaint other
2.1
9.7
99
503
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
17.7
9.4
14
8
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
30.3
9.4
12
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.2
9.4
36
114
H22.0*B00.5
ICD-10 Finland
Herpesviral iridocyclitis
+∞
9.4
9
*
H21.0
ICD-10 Finland
Hyphaema
+∞
9.4
9
*
37403
ICD-8 Finland
Cataract, Complicata
+∞
9.4
9
*
E85.80
ICD-10 Finland
Meretoja sick
+∞
9.4
9
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
9.3
410
3121
A12AA04
ATC
calcium carbonate; oral
4.6
9.3
22
49
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.1
9.3
25
62
H25.8
ICD-10 Finland
Other senile cataract
1.9
9.2
115
628
S01FA01
ATC
atropine; ophthalmic
13.8
9.2
15
11
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
7.8
9.2
20
26
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.7
9.0
28
77
S01AA12
ATC
tobramycin; ophthalmic
18.8
8.9
13
7
D11AX14
ATC
[U] tacrolimus
12.7
8.9
15
12
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
12.7
8.9
15
12
3661A
ICD-9 Finland
Cataract, Senile cataract
8.0
8.9
19
24
TQW40
NOMESCO Finland
Remowal of suture of skin
2.2
8.8
74
349
TK800
NOMESCO Finland
Hemodialysis
3.6
8.7
28
79
A02BC02
ATC
pantoprazole; systemic
1.5
8.7
658
5566
S05.2
ICD-10 Finland
Ocular laceration and rupture with prolapse or loss of intraocular tissue
50.4
8.7
10
*
S05.3
ICD-10 Finland
Ocular laceration without prolapse or loss of intraocular tissue
50.4
8.7
10
*
H02.4
ICD-10 Finland
Ptosis of eyelid
2.9
8.6
39
137
H3603, E103,
ICD-10 Finland
9.1
8.5
17
19
CF2S4
NOMESCO Finland
Photography of conjunctiva
27.8
8.5
11
*
N18.8
ICD-10 Finland
Other chronic renal failure
3.4
8.4
29
86
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
4.5
8.4
20
45
3700A
ICD-9 Finland
Keratitis, Corneal ulcer
+∞
8.3
8
*
36399
ICD-8 Finland
Keratitis, Without mention of ulcer
+∞
8.3
8
*
L04AX01
ATC
azathioprine; systemic
2.7
8.3
45
174
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.4
8.1
28
83
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
8.1
87
451
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
33.6
8.1
10
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
8.1
103
567
S01EE05
ATC
tafluprost; ophthalmic
2.7
8.0
42
159
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
8.0
198
1317
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.6
8.0
46
183
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.0
417
3260
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.4
7.9
52
221
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
4.1
7.8
21
52
H54.0
ICD-10 Finland
Blindness, binocular
45.3
7.7
9
*
CBG99
NOMESCO Finland
Other operation for trichiasis
45.3
7.7
9
*
37404
ICD-8 Finland
Cataract, Secundaria
45.3
7.7
9
*
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
45.3
7.7
9
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.7
7.7
40
151
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
7.7
66
314
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
7.7
42
163
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.6
7.7
18
40
L04AD01
ATC
ciclosporin; systemic
3.8
7.7
23
62
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.1
7.6
31
102
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
25.2
7.6
10
*
A11CC03
ATC
alfacalcidol; systemic
3.3
7.6
28
87
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
7.5
365
2810
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
80.7
7.4
8
*
C03CA01
ATC
furosemide; systemic
1.5
7.4
296
2188
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
7.4
67
326
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
7.4
166
1078
3716A
ICD-9 Finland
Corneal opacity and other disorders of cornea, Keratoconus
+∞
7.3
7
*
H15.0
ICD-10 Finland
Scleritis
+∞
7.3
7
*
H18.3
ICD-10 Finland
Changes in corneal membranes
+∞
7.3
7
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
7.3
7
*
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
+∞
7.3
7
*
3651
FHL
Penetrating corneal transplantation and cataract surgery
+∞
7.3
7
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
7.3
7
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.1
7.2
64
309
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
7.2
183
1223
S01ED02
ATC
betaxolol; ophthalmic
4.5
7.2
17
38
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.2
7.2
28
90
CGE50
NOMESCO Finland
Excision of pterygium
30.2
7.2
9
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
8.9
7.1
14
16
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
7.0
336
2569
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
3.9
7.0
20
52
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.3
7.0
25
76
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
9.4
6.8
13
14
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.2
6.8
17
28
CKC12
NOMESCO Finland
Photocoagulation of retina
2.4
6.8
43
180
Z97.0
ICD-10 Finland
Presence of artificial eye
40.3
6.8
8
*
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
16.8
6.7
10
6
H54.4
ICD-10 Finland
Blindness, monocular
16.8
6.7
10
6
Z2445
NOMESCO Finland
Psychologist
2.5
6.7
40
162
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
22.7
6.7
9
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.1
6.6
18
45
H53.1
ICD-10 Finland
Subjective visual disturbances
2.1
6.6
65
327
J01MA12
ATC
levofloxacin; systemic
1.6
6.6
176
1189
S01KA02
ATC
hypromellose; ophthalmic
3.5
6.6
22
64
H26.1
ICD-10 Finland
Traumatic cataract
8.8
6.6
13
15
Z2446
NOMESCO Finland
Social worker
2.0
6.6
68
349
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
10.1
6.5
12
12
D11AH01
ATC
tacrolimus; topical
6.9
6.5
15
22
H02AB07
ATC
prednisone; oral
1.7
6.5
129
809
H10
ICD-10 Finland
Conjunctivitis
2.0
6.5
64
323
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
70.3
6.4
7
*
37520
ICD-8 Finland
Glaucoma, Secondary
70.3
6.4
7
*
CGD99
NOMESCO Finland
Other operation for error of refraction
70.3
6.4
7
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.4
608
5217
M54.5
ICD-10 Finland
Low back pain
1.4
6.4
330
2550
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
6.4
109
657
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.4
310
2371
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
2.1
6.3
60
298
Z49.0
ICD-10 Finland
Preparatory care for dialysis
6.0
6.3
16
27
36300
ICD-8 Finland
Keratitis, Ulcerosa
+∞
6.3
6
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
6.3
6
*
37108
ICD-8 Finland
Corneal opacity, Alia definita
+∞
6.3
6
*
T85.3
ICD-10 Finland
Mechanical complication of other ocular prosthetic devices, implants and grafts
+∞
6.3
6
*
Z3226
NOMESCO Finland
Physiotherapist
1.6
6.3
172
1170
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
26.8
6.2
8
*
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
26.8
6.2
8
*
H16
ICD-10 Finland
Keratitis
26.8
6.2
8
*
H44.5
ICD-10 Finland
Degenerated conditions of globe
26.8
6.2
8
*
F99
ICPC
Eye/adnexa disease other
7.1
6.2
14
20
F02
ICPC
Red eye
2.4
6.2
42
181
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.3
6.2
44
194
L04AA06
ATC
mycophenolic acid; systemic
3.4
6.2
21
62
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.3
6.2
22
67
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.8
6.2
16
28
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.1
360
2843
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.6
6.1
33
128
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.5
6.1
37
152
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
6.1
152
1011
P03
ICPC
Feeling depressed
1.9
6.0
80
447
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
77
65
12.72
77.14
1.6
1.3
—
—
—
0
0
44
40
11.44
41.77
1.5
1.2
—
—
—
0
0
541
4013
1.73
16.40
9.0
6.0
27.16
27.57
%
0.40
506
3767
534
3953
1.72
16.25
8.6
5.8
57.81
57.37
%
0.37
495
3711
229
1376
1.85
13.99
4.6
3.5
0.81
0.82
mmol/l
0.36
211
1295
255
1587
1.80
13.88
4.6
3.9
215.86
338.22
ng/l
0.63
196
1247
486
3629
1.64
13.38
6.9
4.9
34.61
35.43
g/l
2.34
452
3383
545
4189
1.63
13.34
9.8
6.9
1.21
1.21
mmol/l
0.45
461
3555
459
3383
1.64
13.28
2.7
2.3
76.51
76.99
nmol/l
0.13
409
3016
609
4866
1.61
12.29
12.1
9.0
4.16
4.11
e9/l
0.19
536
4253
165
928
1.93
12.24
5.1
4.3
242.71
257.91
u/l
0.64
156
881
214
1323
1.78
11.71
3.9
2.3
12.56
13.00
umol/l
0.40
193
1235
759
6447
1.66
11.54
9.4
7.6
83.63
79.59
u/l
0.82
722
6060
220
1382
1.75
11.36
2.1
1.9
—
—
—
0
0
452
3419
1.57
11.13
2.1
2.0
97.14
94.91
pmol/l
0.41
233
1772
184
1112
1.80
10.80
10.8
5.7
1.09
1.04
mmol/l
1.59
172
1028
166
973
1.84
10.77
3.3
2.8
1.89
1.79
%
0.54
138
875
493
3823
1.55
10.75
8.6
6.2
1.21
1.21
mmol/l
0.64
450
3482
727
6175
1.59
10.38
5.2
3.9
14.40
12.43
mm/h
2.46
680
5693
664
5531
1.56
10.27
5.3
4.5
2470.00
2890.21
e6/l
—
7
90
507
3986
1.53
10.20
19.9
15.4
1.27
1.27
inr
0.02
148
1165
398
2969
1.55
10.17
4.7
3.7
104.37
119.34
e6/l
0.15
288
2134
196
1228
1.74
10.12
4.0
2.3
2.24
2.32
g/l
1.21
178
1141
923
8383
1.92
9.89
22.1
14.3
24.93
24.53
mg/l
0.13
756
6617
548
4400
1.52
9.86
7.1
6.5
12.10
11.51
umol/l
0.26
517
4177
120
652
1.95
9.79
5.5
3.7
110.80
81.87
ng/l
1.92
108
567
738
6326
1.58
9.79
4.3
3.9
14.78
14.84
pmol/l
0.26
663
5732
238
1588
1.65
9.67
1.9
1.7
1121.22
1194.50
nmol/l
0.66
186
1181
185
1156
1.73
9.61
4.2
2.4
21.88
23.00
%
0.51
158
989
300
2150
1.56
8.94
2.5
2.2
2.99
3.06
mg/l
0.16
252
1824
156
952
1.75
8.77
2.0
1.8
—
—
—
0
0
214
1422
1.64
8.76
3.0
2.7
0.81
1.14
e6/l
1.56
131
824
297
2133
1.55
8.74
5.4
3.9
86.88
89.59
%
0.91
288
2091
855
7679
1.65
8.45
6.5
5.8
40.29
39.94
mmol/mol
0.48
789
7104
156
962
1.73
8.44
2.1
1.8
—
—
—
0
0
935
8624
1.86
8.15
25.0
16.8
139.46
139.60
mmol/l
0.97
917
8391
27
78
3.53
8.13
1.2
1.1
—
—
—
0
0
316
2336
1.51
8.02
4.1
3.1
0.40
0.50
e6/l
0.45
248
1786
127
749
1.79
8.00
13.6
7.3
10.78
9.50
mmol/l
1.30
122
709
850
7658
1.61
7.89
5.3
4.6
1.98
2.09
mu/l
0.28
770
6981
957
8908
1.96
7.88
13.7
10.4
26.09
26.74
u/l
0.45
926
8593
935
8647
1.83
7.75
25.6
16.9
3.99
3.98
mmol/l
0.64
916
8394
592
4982
1.44
7.48
6.2
5.0
6.82
6.72
mmol/l
0.58
554
4679
42
167
2.58
7.33
1.4
1.3
—
—
—
0
0
42
167
2.58
7.33
1.4
1.3
—
—
—
0
0
447
3585
1.43
7.29
4.3
2.7
144.68
133.61
ug/l
0.37
407
3287
371
2879
1.45
7.21
3.6
3.5
2.34
2.35
mmol/l
0.50
327
2527
52
233
2.30
7.03
1.7
1.7
—
—
—
0
0
335
2561
1.46
7.01
4.3
3.2
89.19
87.83
e6/l
0.01
266
1983
332
2541
1.45
6.88
2.5
2.1
225.80
262.34
u/l
0.29
313
2403
862
7877
1.56
6.60
18.1
13.3
79.40
80.66
ml/min/173m2
0.78
719
6486
131
824
1.68
6.55
8.8
4.0
1.85
2.03
mmol/l
0.25
114
682
66
335
2.04
6.55
1.8
2.1
39.15
40.16
u/l
0.14
61
296
12
13
9.32
6.29
1.2
1.1
—
—
—
0
0
105
634
1.73
6.10
1.8
1.6
—
—
—
0
0
349
2746
1.41
6.06
3.5
3.3
30.75
33.91
u/l
1.37
332
2604
39
165
2.42
6.03
1.6
1.6
—
—
—
0
0
71
383
1.92
5.95
1.9
2.0
1.56
1.52
g/l
0.10
61
338
335
2629
1.41
5.87
4.0
2.6
59.81
87.62
u/l
0.44
314
2444
129
832
1.63
5.85
8.9
4.0
5.98
5.85
kpa
0.66
122
809
876
8097
1.53
5.70
4.9
4.6
5.98
5.95
mmol/l
0.19
791
7340
219
1598
1.47
5.68
1.7
1.5
2.50
2.49
g/l
0.03
137
983
488
4093
1.36
5.63
5.9
4.9
0.00
0.00
estimate
0.50
82
788
493
4143
1.36
5.61
4.3
3.7
0.00
0.00
estimate
0.50
76
767
34
140
2.48
5.58
1.3
1.3
—
—
—
0
0
188
1338
1.49
5.51
3.2
2.9
1.43
2.33
e6/l
1.55
105
742
112
710
1.65
5.44
4.3
3.0
364.62
195.53
ng/l
1.14
104
646
24
84
2.90
5.38
1.1
1.2
59.58
52.29
u/l
0.39
24
78
141
949
1.56
5.35
3.5
2.9
9.51
8.94
umol/l
0.08
123
825
979
9327
1.89
5.35
31.8
21.1
247.79
248.04
e9/l
0.04
958
9077
798
7270
1.42
5.34
26.7
17.1
14.97
14.92
%
0.08
780
7145
52
262
2.04
5.31
1.7
1.6
—
126.67
—
0
9
280
2164
1.40
5.27
3.2
2.7
354.26
7021.64
umol/l
8.38
250
1892
979
9333
1.88
5.25
31.7
21.1
4.41
4.49
e12/l
5.60
953
9049
979
9337
1.87
5.18
32.0
21.3
133.27
135.41
g/l
4.07
968
9185
899
8394
1.53
5.17
5.3
4.9
2.68
2.73
mmol/l
1.02
821
7706
484
4092
1.34
5.14
4.2
3.7
0.00
0.00
estimate
0.50
85
836
978
9328
1.85
5.12
31.7
21.3
39.43
40.13
%
2.52
912
8690
55
287
1.97
5.11
1.7
2.8
10.48
10.49
g/l
0.01
49
254
236
1785
1.42
5.00
3.8
2.6
4.95
5.71
e6/l
0.35
214
1618
243
1858
1.40
4.82
2.1
1.7
1.17
1.18
mg/l
0.01
182
1418
240
1833
1.40
4.79
1.4
1.2
1.75
1.86
u/ml
0.05
62
502
15
42
3.61
4.78
1.3
1.1
—
—
—
0
0
49
252
1.99
4.76
2.1
1.3
1.15
1.19
g/l
0.25
44
239
260
2026
1.38
4.58
1.7
1.5
20.13
20.67
nmol/l
0.22
219
1717
105
685
1.59
4.56
1.9
3.0
66.26
66.51
g/l
0.11
94
624
53
288
1.89
4.41
1.7
2.8
3.11
3.03
g/l
0.20
47
256
48
254
1.93
4.32
1.4
1.5
0.06
24.77
iu/ml
0.50
13
49
55
306
1.84
4.26
1.7
2.7
3.55
3.60
g/l
0.13
49
275
137
963
1.49
4.25
2.0
2.4
109.13
134.74
ug/g
0.60
112
780
55
307
1.84
4.22
1.7
2.7
—
—
—
0
0
55
307
1.84
4.22
1.7
2.7
7.60
7.43
g/l
0.22
49
275
15
46
3.29
4.20
1.2
1.1
99.47
74.55
u/l
0.62
15
40
14
41
3.45
4.19
1.6
3.0
663.79
1710.71
u/ml
0.94
14
41
879
8253
1.43
4.09
4.8
4.4
4.56
4.63
mmol/l
1.14
809
7625
308
2502
1.33
4.08
3.6
3.1
1574.49
1351.54
ng/l
0.48
267
2132
8
10
8.05
4.06
11.1
4.3
—
—
—
0
0
874
8202
1.42
4.03
4.6
4.3
1.42
1.46
mmol/l
1.75
795
7533
111
755
1.53
4.03
3.5
2.4
38.16
34.46
u/l
0.41
93
642
619
5527
1.30
4.03
3.9
3.2
54.56
51.25
u/l
0.30
575
5155
848
7919
1.39
4.02
4.2
3.9
1.28
1.29
mmol/l
0.27
767
7224
48
261
1.88
4.01
1.5
1.6
—
—
—
0
0
206
1579
1.38
3.97
2.8
3.0
2.45
2.45
mmol/l
0.12
181
1392
66
398
1.70
3.92
1.1
1.0
—
—
—
0
0
105
712
1.53
3.87
7.0
3.3
4.71
4.47
kpa
0.64
98
692
51
287
1.82
3.84
1.4
1.2
1.07
1.48
u/ml
—
6
20
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
280
1.83
3.82
4.6
2.8
0.37
0.34
u/ml
0.21
28
162
46
251
1.87
3.81
1.7
2.7
37.61
37.36
g/l
0.09
40
219
14
44
3.21
3.78
1.2
1.1
29.36
15.57
u/l
0.71
14
37
39
202
1.97
3.77
2.1
1.7
—
—
—
0
0
111
770
1.49
3.68
2.7
2.1
356.71
372.12
nmol/l
0.41
103
710
98
666
1.52
3.59
2.7
2.7
57.39
66.31
ml/min/173m2
1.20
41
282
301
2482
1.30
3.50
4.0
3.2
706.00
310.54
mg/l
0.54
199
1595
457
3974
1.27
3.48
3.1
2.6
—
—
—
0
0
255
2058
1.32
3.47
2.9
2.4
—
—
—
0
0
386
3292
1.27
3.44
4.1
3.7
40.35
51.70
ng/l
0.41
281
2319
51
299
1.74
3.38
3.9
3.0
—
—
—
0
0
78
511
1.57
3.37
1.9
1.6
—
—
—
0
0
9
18
5.03
3.37
1.1
1.1
—
—
—
0
0
116
831
1.45
3.29
2.6
2.4
0.21
0.21
g/l
0.30
109
786
172
1322
1.36
3.24
3.1
2.1
29.41
29.61
s
0.18
167
1284
19
78
2.46
3.23
1.1
2.2
—
—
—
0
0
34
179
1.93
3.17
12.5
6.4
1065.70
314.13
iu/ml
—
10
30
38
208
1.86
3.16
1.8
1.7
—
—
—
0
0
318
2671
1.27
3.16
4.6
3.1
7.12
7.67
mmol/l
1.25
275
2248
224
1803
1.31
3.08
1.8
1.7
130107965.77
22666194.52
pmol/l
0.79
186
1478
43
247
1.77
3.08
1.7
1.3
—
—
—
0
0
33
174
1.93
3.07
2.0
2.2
131.12
130.30
g/l
0.06
25
132
6
8
7.54
3.06
13.7
4.8
3.95
8.71
mmol/l
—
6
8
31
161
1.95
3.02
2.1
1.4
104.29
109.54
u/ml
—
7
28
104
746
1.44
2.94
2.4
2.5
4.83
7.19
ug/l
1.65
85
659
44
259
1.73
2.91
1.4
1.2
—
—
—
0
0
131
985
1.38
2.84
7.1
7.8
1.84
1.29
mmol/l
0.84
110
785
568
5149
1.23
2.73
3.0
2.9
—
—
—
0
0
28
146
1.94
2.72
2.0
1.6
—
—
—
0
0
28
146
1.94
2.72
2.0
1.6
—
—
—
0
0
44
265
1.69
2.70
1.8
3.1
1.01
1.19
g/l
0.11
39
233
130
986
1.36
2.68
7.2
7.8
5.26
5.13
kpa
0.83
123
945
130
987
1.36
2.66
7.1
7.7
12.48
12.20
kpa
0.21
123
949
14
55
2.57
2.62
1.4
1.4
—
—
—
0
0
20
93
2.17
2.62
1.7
1.7
—
—
—
0
0
54
346
1.59
2.62
2.2
1.8
—
—
—
0
0
21
101
2.10
2.54
1.8
1.6
—
—
—
0
0
21
101
2.10
2.54
1.8
1.6
—
—
—
0
0
64
431
1.52
2.51
6.8
10.6
24.87
24.59
mmol/l
0.35
59
421
28
151
1.88
2.49
1.8
1.7
—
—
—
0
0
67
458
1.49
2.45
4.2
3.4
4.47
4.63
pmol/l
0.32
59
405
306
2632
1.23
2.37
4.8
3.8
15.29
8.63
mg/mmol
1.30
201
1676
34
200
1.72
2.30
1.6
1.4
—
—
—
0
0
18
85
2.14
2.29
3.1
4.1
—
—
—
0
0
28
156
1.82
2.27
3.4
3.2
3.82
4.43
e9/l
1.07
28
156
7
18
3.91
2.25
1.3
1.1
112.57
88.00
%
—
7
18
29
164
1.79
2.25
3.8
3.4
58.21
59.09
%
0.13
29
164
41
256
1.63
2.24
1.5
4.1
30.25
46.49
mg/l
0.70
32
211
26
144
1.83
2.16
1.3
1.5
—
—
—
0
0
69
488
1.44
2.16
1.6
1.3
417.05
207.67
u/ml
0.83
63
447
6
14
4.30
2.15
1.0
1.2
—
—
—
0
0
54
364
1.51
2.14
2.0
2.0
2.17
2.16
ug/l
0.00
46
325
47
310
1.54
2.07
2.0
1.9
—
—
—
0
0
57
392
1.48
2.06
2.1
2.0
—
—
—
0
0
38
239
1.61
2.04
1.5
1.5
205.24
288.18
ug/g
2.01
20
147
114
887
1.32
2.02
3.6
3.3
—
—
—
0
0
48
320
1.52
2.02
1.9
1.7
—
—
—
0
0
40
256
1.59
2.00
1.6
4.0
44.94
76.95
mg/l
0.69
31
210
22
119
1.87
1.98
1.6
1.6
—
—
—
0
0
17
84
2.04
1.96
2.9
2.3
—
—
—
0
0
165
1364
1.25
1.83
1.5
1.5
—
—
—
0
0
5
12
4.18
1.82
3.2
2.4
—
—
—
0
0
28
168
1.69
1.82
2.4
2.4
16.38
16.37
%
0.00
18
90
12
53
2.28
1.81
8.8
2.0
—
—
—
0
0
9
35
2.58
1.80
1.0
1.1
1197.06
254.65
iu/ml
—
9
35
13
60
2.18
1.78
1.5
1.2
—
—
—
0
0
164
1360
1.24
1.77
1.3
1.3
30.01
33.66
iu/ml
0.20
58
426
17
88
1.95
1.75
1.3
1.3
12323.00
47575.31
e6/l
—
10
51
12
55
2.20
1.67
1.5
1.4
—
—
—
0
0
18
97
1.87
1.67
1.3
1.3
1523.85
1800.88
e6/l
0.12
13
67
6
20
3.01
1.58
4.2
1.9
—
—
—
0
0
43
299
1.46
1.53
1.6
1.4
27.34
26.58
iu/l
0.06
36
247
33
219
1.52
1.47
1.3
1.2
3.00
8.68
u/ml
—
7
32
72
552
1.33
1.46
5.5
3.7
1.42
1.83
mmol/l
0.26
51
415
17
95
1.80
1.43
2.0
1.8
—
—
—
0
0
317
2849
1.16
1.43
5.1
4.8
1.98
2.73
ug/l
1.35
289
2551
16
88
1.83
1.42
2.1
1.8
—
—
—
0
0
10
46
2.19
1.40
1.6
1.4
—
—
—
0
0
10
46
2.19
1.40
1.6
1.4
—
—
—
0
0
14
74
1.90
1.39
1.0
1.7
—
—
—
0
0
7
29
2.42
1.39
1.0
1.5
—
—
—
0
0
38
264
1.46
1.38
2.1
1.7
—
—
—
0
0
20
119
1.69
1.38
1.8
1.5
—
—
—
0
0
20
119
1.69
1.38
1.8
1.5
—
—
—
0
0
75
584
1.31
1.38
5.5
3.6
5.21
5.13
kpa
0.28
67
567
18
104
1.74
1.37
1.3
1.4
—
—
—
0
0
212
1851
1.18
1.37
4.3
4.0
1.02
1.02
kg/l
0.03
35
259
20
120
1.68
1.35
1.8
1.5
—
—
—
0
0
19
113
1.69
1.32
1.2
1.5
—
—
—
0
0
50
369
1.37
1.32
6.7
4.2
25.15
24.90
mmol/l
0.13
43
349
17
98
1.75
1.31
3.2
8.4
7.64
7.03
mmol/l
0.23
12
81
20
121
1.67
1.31
1.8
1.5
—
—
—
0
0
20
121
1.67
1.31
1.8
1.5
—
—
—
0
0
20
121
1.67
1.31
1.8
1.5
—
—
—
0
0
9
43
2.10
1.30
1.0
1.7
1.18
1.22
nmol/l
—
9
32
33
226
1.48
1.30
2.8
2.3
260.61
85.62
ug/min
0.99
23
141
9
172
0.52
1.30
1.7
1.4
—
—
—
0
0
9
172
0.52
1.30
1.7
1.4
—
—
—
0
0
9
172
0.52
1.30
1.7
1.4
—
—
—
0
0
9
172
0.52
1.30
1.7
1.4
—
—
—
0
0
31
210
1.49
1.29
2.0
1.7
32210.37
16007.68
e6/l
0.50
24
152
22
138
1.61
1.27
1.6
1.2
3.92
4.54
u/ml
0.09
12
37
153
1309
1.20
1.25
1.2
1.3
25.17
12.52
u/ml
0.53
41
483
67
522
1.30
1.25
1.6
1.4
—
—
—
0
0
8
37
2.17
1.21
2.6
1.6
—
—
—
0
0
38
272
1.41
1.21
6.1
2.4
92.11
90.88
%
0.13
38
260
17
101
1.69
1.20
3.2
2.6
21.00
30.94
mg/l
—
6
27
32
222
1.46
1.20
1.7
1.6
—
—
—
0
0
13
71
1.84
1.19
1.3
1.1
—
—
—
0
0
6
26
2.32
1.19
1.5
1.3
—
—
—
0
0
33
231
1.44
1.18
1.5
1.4
—
—
—
0
0
8
39
2.06
1.15
1.1
1.7
9.19
8.25
mmol/l
—
8
39
27
183
1.49
1.14
1.7
1.2
—
—
—
0
0
247
2221
1.15
1.10
1.8
1.7
1.34
1.38
mmol/l
0.38
215
1865
5
21
2.39
1.09
1.2
1.0
—
—
—
0
0
8
41
1.96
1.09
1.1
1.2
—
—
—
0
0
7
32
2.20
1.08
2.0
2.3
—
—
—
0
0
11
59
1.87
1.07
1.4
1.1
—
—
—
0
0
11
59
1.87
1.07
1.4
1.1
—
—
—
0
0
10
52
1.93
1.06
1.1
1.2
—
—
—
0
0
26
178
1.47
1.06
1.3
1.2
—
—
—
0
0
28
195
1.45
1.05
3.6
1.5
38.57
8.64
e6/l
0.57
23
153
9
46
1.96
1.03
1.0
1.0
—
—
—
0
0
5
22
2.28
1.03
1.2
1.2
—
—
—
0
0
5
22
2.28
1.03
1.2
1.3
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
11
60
1.84
1.03
1.4
1.1
—
—
—
0
0
11
60
1.84
1.03
1.4
1.1
—
—
—
0
0
11
60
1.84
1.03
1.4
1.1
—
—
—
0
0
10
54
1.86
0.96
13.7
21.6
1209.80
1499.09
nmol/l
—
10
54
9
50
1.81
0.96
3.7
1.6
—
—
—
0
0
27
192
1.42
0.93
3.4
1.4
3.79
3.75
mmol/l
0.07
27
180
12
196
0.61
0.93
1.5
1.5
—
—
—
0
0
6
28
2.15
0.91
1.5
1.2
12.37
9.18
ug/l
—
6
28
28
202
1.40
0.90
1.8
1.8
2.74
5.62
iu/l
—
8
67
20
135
1.49
0.89
1.1
1.1
164.30
76.60
iu/ml
—
5
30
83
695
1.21
0.89
6.0
3.7
1.22
1.23
mmol/l
0.30
70
604
6
30
2.01
0.87
1.5
2.1
85.67
136.76
nmol/l
—
6
25
19
129
1.48
0.83
1.3
1.5
—
—
—
0
0
11
178
0.61
0.83
1.7
1.5
—
—
—
0
0
11
65
1.70
0.82
1.1
1.7
—
—
—
0
0
249
2288
1.12
0.79
4.2
4.3
21.39
20.98
%
0.17
122
1084
22
156
1.42
0.79
2.1
1.6
—
—
—
0
0
8
48
1.67
0.79
1.6
1.4
187.88
171.26
pmol/l
—
8
48
31
234
1.33
0.78
1.5
1.8
42.26
39.26
nmol/l
0.46
31
224
28
208
1.36
0.78
1.3
1.1
—
—
—
0
0
29
217
1.35
0.77
1.1
1.3
208.90
247.66
miu/ml
—
9
104
77
653
1.19
0.75
2.9
2.2
12.70
13.20
nmol/l
0.24
71
594
7
38
1.85
0.73
1.7
2.8
30017.57
38318.55
ug/l
—
7
38
5
25
2.00
0.72
1.0
1.0
1155.60
1544.68
miu/ml
—
5
25
10
60
1.67
0.72
1.4
1.3
—
—
—
0
0
9
57
1.58
0.71
1.0
1.0
—
—
—
0
0
5
26
1.93
0.70
1.4
1.3
—
—
—
0
0
17
118
1.45
0.69
1.1
1.0
0.90
1.67
u/ml
—
10
52
32
248
1.30
0.69
1.3
1.1
—
—
—
0
0
10
61
1.65
0.68
1.4
1.3
—
—
—
0
0
9
59
1.53
0.68
1.1
1.0
220.44
244.69
mg/l
—
9
52
30
231
1.31
0.68
1.1
1.1
9.28
4.90
u/ml
—
5
29
15
102
1.48
0.67
1.3
1.2
0.65
0.59
nmol/l
0.22
15
95
29
223
1.31
0.67
1.6
1.4
10.22
9.05
u/l
0.15
23
179
32
251
1.28
0.64
1.3
1.1
—
—
—
0
0
22
292
0.75
0.64
1.9
1.5
—
—
—
0
0
28
217
1.30
0.62
1.4
1.3
—
—
—
0
0
16
113
1.42
0.61
1.2
1.5
—
—
—
0
0
8
50
1.60
0.61
2.3
2.5
—
—
—
0
0
114
1020
1.13
0.59
1.7
1.8
1.69
1.50
%
0.94
102
889
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
6
36
1.67
0.56
2.5
1.9
—
—
—
0
0
6
36
1.67
0.56
2.5
1.9
—
—
—
0
0
6
36
1.67
0.56
2.5
1.9
—
—
—
0
0
16
218
0.73
0.56
1.4
1.4
—
—
—
0
0
241
2255
1.09
0.55
4.8
3.9
0.00
0.01
estimate
0.88
79
759
6
38
1.58
0.54
1.3
1.3
—
—
—
0
0
336
3195
1.08
0.51
4.7
3.8
—
—
—
0
0
18
135
1.34
0.51
1.8
1.2
5.18
4.07
u/ml
0.29
11
54
63
548
1.16
0.50
1.3
1.2
110.54
131.09
iu/ml
0.20
23
215
7
46
1.53
0.48
2.6
1.7
—
—
—
0
0
7
46
1.53
0.48
1.1
6.7
—
85.58
—
0
12
7
46
1.53
0.48
2.6
1.7
—
—
—
0
0
11
76
1.45
0.48
1.0
1.1
—
—
—
0
0
7
47
1.49
0.47
1.4
1.1
—
—
—
0
0
7
50
1.40
0.45
1.4
1.3
1.52
1.56
g/l
—
7
50
122
1120
1.10
0.43
1.4
1.4
—
—
—
0
0
16
122
1.32
0.42
1.1
1.1
—
—
—
0
0
47
408
1.16
0.41
1.4
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
8.67
—
0
11
0
19
0.00
0.39
0.0
1.1
—
22.09
—
0
19
15
116
1.30
0.37
1.3
1.7
—
—
—
0
0
14
108
1.30
0.35
1.0
1.0
—
—
—
0
0
6
44
1.37
0.34
4.0
1.8
—
—
—
0
0
6
44
1.37
0.34
4.0
1.8
—
—
—
0
0
11
82
1.35
0.34
2.0
1.6
—
—
—
0
0
11
82
1.35
0.34
2.0
1.6
—
—
—
0
0
11
82
1.35
0.34
2.0
1.6
—
—
—
0
0
6
46
1.31
0.33
1.0
1.6
—
—
—
0
0
6
46
1.31
0.33
1.3
1.7
1.67
2.84
u/field
—
6
31
6
47
1.28
0.32
1.0
1.6
—
—
—
0
0
174
1647
1.07
0.32
3.2
3.0
0.66
0.75
ug/l
1.24
127
1069
7
52
1.35
0.31
1.7
1.5
—
—
—
0
0
7
55
1.27
0.30
1.3
1.7
—
—
—
0
0
8
110
0.73
0.29
1.1
1.1
—
—
—
0
0
16
130
1.23
0.29
1.1
1.1
122.56
115.77
%
0.33
16
118
78
719
1.09
0.28
2.2
1.9
—
—
—
0
0
21
177
1.19
0.27
3.9
3.9
19.48
26.58
mg/l
0.68
15
112
8
64
1.25
0.27
1.5
1.6
0.89
1.01
g/l
—
8
64
8
66
1.21
0.26
1.3
1.1
—
81.83
—
0
6
9
74
1.22
0.25
1.0
1.3
—
—
—
0
0
11
87
1.27
0.24
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
20
174
1.15
0.19
1.3
1.9
204.05
224.29
pmol/l
0.40
20
163
11
90
1.22
0.19
1.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
52
1.15
0.19
1.5
1.2
—
—
—
0
0
6
53
1.13
0.18
1.0
1.5
—
—
—
0
0
34
309
1.10
0.18
1.4
1.8
3.25
3.31
mg/l
0.02
27
230
14
119
1.18
0.17
1.6
2.4
34.36
32.67
pg
0.98
14
119
8
68
1.18
0.16
1.3
1.4
—
—
—
0
0
21
187
1.13
0.16
1.1
1.4
—
—
—
0
0
8
73
1.10
0.15
1.1
1.0
287.50
284.19
mg/l
—
8
64
27
297
0.91
0.15
1.9
1.8
—
—
—
0
0
6
79
0.76
0.15
1.0
1.1
—
—
—
0
0
107
1028
1.05
0.14
4.3
4.5
33.14
31.93
%
0.56
70
689
8
98
0.81
0.13
1.5
1.5
—
—
—
0
0
31
332
0.93
0.11
2.6
3.6
34.35
3859.07
u/ml
0.72
26
291
24
221
1.09
0.11
1.2
1.2
—
—
—
0
0
15
135
1.11
0.09
1.1
1.1
—
—
—
0
0
5
61
0.82
0.08
1.8
1.6
121.00
81.38
umol/l
—
5
61
24
225
1.07
0.07
3.3
2.2
8446.21
2656.96
u/l
—
9
93
7
85
0.82
0.07
2.7
2.7
—
—
—
0
0
11
122
0.90
0.07
1.5
1.6
—
—
—
0
0
16
148
1.08
0.06
1.4
1.7
—
—
—
0
0
21
223
0.94
0.06
1.4
1.5
—
—
—
0
0
83
811
1.03
0.05
2.3
2.0
—
—
—
0
0
11
100
1.10
0.05
2.5
2.0
—
1506.67
—
0
6
91
893
1.02
0.04
4.1
4.2
152.71
27.21
ug/l
0.48
77
748
15
140
1.07
0.04
1.1
1.1
—
11.81
—
0
11
13
137
0.95
0.01
1.2
1.1
—
—
—
0
0
72
727
0.99
0.01
2.1
1.7
—
—
—
0
0
11
114
0.96
0.00
1.0
1.1
2.33
1.92
u/ml
—
6
62
12
124
0.97
0.00
1.2
1.1
1.65
1.53
g/l
0.36
12
113
105
1055
0.99
0.00
9.2
7.6
—
—
—
0
0
14
135
1.04
0.00
1.1
1.1
1.40
3.12
u/ml
—
9
74
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
4.55
—
0
6
9
90
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
14.33
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.4
1.1
—
—
—
0
0
9
95
0.95
-0.00
1.4
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_CORNEALSCAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALSCAR | 1.124 [0.99, 1.28] | 0.082 |
| Birth year | 0.992 [0.98, 1.0] | 0.07 |
During the follow-up period (1.1.1998 — 31.12.2019), 740 out of 2917 females with H7_CORNEALSCAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CORNEALSCAR | 1.186 [1.02, 1.38] | 0.028 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 559 out of 2918 males with H7_CORNEALSCAR died.
Mortality risk
Mortality risk for people of age
years, who have H7_CORNEALSCAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.082% | 0.264% |
| 5 | 0.564% | 1.544% |
| 10 | 1.441% | 3.449% |
| 15 | 2.847% | 6.67% |
| 20 | 5.252% | 10.94% |
Relationships between endpoints
↥Index endpoint: H7_CORNEALSCAR – Corneal scars and opacities
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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