No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
159 |
4. Check minimum number of eventsNone |
159 |
5. Include endpointsNone |
159 |
6. Filter based on genotype QC (FinnGen only) |
147 |
Control definitions (FinnGen only)
- Control exclude
- AB1_VIRAL_CNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Tick-borne viral encephalitis
based on the number of shared cases.
Similar with more cases:
- Viral infections of the central nervous system
- Viral infections of the central nervous system
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1177 | 458 | 710 |
| Only index persons | 1085 | 435 | 650 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 49.62 | 50.46 | 48.87 |
| Only index persons | 50.10 | 50.59 | 49.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 147 | 74 | 73 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 56.19 | 54.62 | 57.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 159
- Matched controls
- 1590
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A84.8
ICD-10 Finland
Other tick-borne viral encephalitis
+∞
82.7
72
*
A84.9
ICD-10 Finland
Tick-borne viral encephalitis, unspecified
+∞
71.3
63
*
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
35.8
33
*
XA800
NOMESCO Finland
Neuropsychological investigation
13.2
35.7
38
37
TAB00
NOMESCO Finland
Lumbar puncture
10.9
33.3
41
49
R50.9
ICD-10 Finland
Fever, unspecified
5.6
22.5
57
145
AA1AD
NOMESCO Finland
CT of head and brain
4.9
22.2
78
260
A87.9
ICD-10 Finland
Viral meningitis, unspecified
+∞
21.3
20
*
A69.2
ICD-10 Finland
Lyme disease
8.4
18.9
27
38
A84.1
ICD-10 Finland
Central European tick-borne encephalitis
+∞
18.1
17
*
R4120
NOMESCO Finland
Occupational therapy
6.3
15.6
29
54
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.0
12.9
31
73
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
+∞
12.7
12
*
0632A
ICD-9 Finland
Tick-borne viral encephalitis, Central European encephalitis[PUUTIAISEN VÄLITTÄMÄ ENKEFALIITTI (KUMLINGE)]
+∞
9.5
9
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
53.0
8.8
10
*
A84
ICD-10 Finland
Tick-borne viral encephalitis
+∞
8.4
8
*
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
+∞
7.3
7
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.6
7.2
16
23
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
7.1
86
517
B34.9
ICD-10 Finland
Viral infection, unspecified
9.3
6.7
13
15
N29
ICPC
Neurological sympt/complt other
13.0
6.7
11
9
G03.9
ICD-10 Finland
Meningitis, unspecified
27.9
6.3
8
*
N71
ICPC
Meningitis/encephalitis
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
12
62.10
88.13
1.1
1.0
—
—
—
0
0
49
11
63.94
85.42
1.1
1.4
—
—
—
0
0
80
99
15.25
66.71
3.3
2.4
27.08
8.23
au/ml
—
13
6
76
89
15.44
65.69
1.8
1.2
69.19
27.79
au/ml
—
10
7
53
34
22.88
64.52
1.1
1.2
58.93
332.15
e6/l
0.80
29
27
53
34
22.88
64.52
1.1
1.1
92.11
3.46
e6/l
2.56
28
26
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
52
7
109.09
49.57
1.0
1.3
—
—
—
0
0
50
6
120.19
48.18
1.2
1.3
—
—
—
0
0
34
22
19.39
40.35
1.3
1.1
—
—
—
0
0
28
34
9.78
22.10
1.1
1.1
—
—
—
0
0
24
5
56.07
20.81
1.3
1.6
2.17
2.25
mmol/l
—
24
5
19
8
26.72
14.16
1.1
1.0
—
—
—
0
0
17
5
37.75
13.81
1.0
1.0
—
—
—
0
0
23
39
6.73
13.48
1.3
2.0
—
—
—
0
0
30
67
5.29
13.25
1.4
1.9
—
—
—
0
0
21
15
15.92
13.19
1.2
1.9
—
—
—
0
0
21
17
14.03
12.55
1.0
1.2
—
—
—
0
0
24
30
9.22
11.60
1.1
1.4
—
—
—
0
0
52
202
3.34
10.70
1.5
1.9
—
—
—
0
0
14
6
25.38
10.44
1.0
1.2
—
—
—
0
0
17
13
14.47
10.43
1.2
2.1
—
—
—
0
0
38
143
3.18
8.04
1.5
1.8
—
—
—
0
0
7
0
+∞
7.34
1.0
0.0
—
—
—
0
0
50
234
2.66
7.03
2.1
2.8
0.61
0.98
e6/l
0.68
20
125
14
20
7.56
6.38
1.0
1.5
254.50
211.00
u/ml
—
8
8
36
149
2.83
6.36
1.5
1.8
—
—
—
0
0
6
0
+∞
6.29
1.0
0.0
—
—
—
0
0
46
219
2.55
6.17
2.2
2.9
2.85
1.91
e6/l
0.20
18
110
14
23
6.56
5.84
1.0
1.5
—
—
—
0
0
88
572
2.21
5.62
3.3
5.9
1.20
1.22
mmol/l
1.46
75
522
65
379
2.21
5.40
2.5
3.1
0.25
0.45
e6/l
0.70
41
275
15
41
3.94
5.06
1.2
2.4
—
—
—
0
0
75
473
2.11
5.02
1.9
2.0
94.61
92.98
pmol/l
0.08
36
234
90
617
2.06
4.72
3.7
6.9
1.21
1.22
mmol/l
0.71
78
521
113
848
2.15
4.58
2.9
3.1
—
—
—
0
0
12
24
5.32
4.42
1.0
1.5
—
—
—
0
0
105
776
2.04
4.31
8.0
10.3
4.39
4.11
e9/l
0.40
87
676
150
1318
3.44
4.23
16.0
13.9
20.31
23.31
mg/l
0.69
135
1031
123
972
2.17
4.10
3.9
4.0
12.11
11.35
mm/h
0.28
117
902
71
467
1.94
4.00
2.5
3.3
—
—
—
0
0
98
725
1.92
3.80
3.2
4.7
6.71
6.67
mmol/l
0.03
92
673
126
1021
2.13
3.69
7.5
7.9
74.57
79.94
u/l
0.73
121
957
93
698
1.80
3.24
5.2
6.8
10.48
11.38
umol/l
0.53
86
664
7
12
6.04
3.05
1.0
2.2
—
—
—
0
0
7
12
6.04
3.05
1.0
2.2
—
—
—
0
0
7
12
6.04
3.05
1.0
2.2
—
—
—
0
0
9
21
4.48
3.04
1.0
2.0
—
—
—
0
0
9
21
4.48
3.04
1.0
2.0
—
—
—
0
0
5
6
8.55
2.77
1.0
1.0
—
—
—
0
0
5
7
7.33
2.56
1.0
2.6
—
—
—
0
0
5
7
7.33
2.56
1.0
2.6
—
—
—
0
0
152
1405
2.86
2.49
17.1
16.3
73.91
78.46
umol/l
2.51
152
1405
10
33
3.16
2.40
1.1
1.8
—
—
—
0
0
9
28
3.34
2.34
1.2
1.6
—
—
—
0
0
13
53
2.58
2.34
1.2
1.8
—
—
—
0
0
68
501
1.62
2.29
2.3
2.4
72.24
75.17
nmol/l
0.41
59
449
6
13
4.75
2.29
1.2
1.0
—
—
—
0
0
37
232
1.78
2.26
3.5
3.7
18.10
78.32
ng/l
1.46
29
179
5
9
5.69
2.23
2.0
1.8
367.60
1060.00
u/ml
—
5
9
11
43
2.67
2.13
1.1
1.2
—
—
—
0
0
28
164
1.86
2.12
5.2
4.3
33.79
32.47
%
0.22
14
107
23
126
1.96
2.12
1.7
2.4
11.69
13.81
nmol/l
0.71
23
117
5
10
5.12
2.08
1.0
1.0
—
—
—
0
0
48
332
1.64
2.05
2.0
2.8
10120.90
3890.38
umol/l
0.27
41
292
45
308
1.64
1.99
1.5
1.6
19.28
21.95
nmol/l
0.78
33
263
9
33
2.83
1.96
1.1
1.8
—
—
—
0
0
71
549
1.53
1.85
3.1
4.7
35.45
35.86
g/l
0.29
66
519
17
91
1.97
1.68
1.4
1.6
—
—
—
0
0
22
130
1.80
1.63
3.2
7.5
2.29
1.14
mmol/l
0.75
16
107
6
20
3.08
1.59
1.0
1.2
—
—
—
0
0
34
480
0.63
1.59
2.4
3.6
—
—
—
0
0
62
483
1.46
1.50
2.9
3.8
68.57
35.38
ng/l
0.31
47
346
38
268
1.55
1.47
3.2
2.9
0.48
0.69
ug/l
2.32
21
176
5
16
3.19
1.45
1.4
1.1
—
—
—
0
0
5
16
3.19
1.45
1.2
1.6
—
—
—
0
0
70
569
1.41
1.31
10.5
12.0
1.02
1.25
inr
—
9
170
48
365
1.45
1.29
3.7
4.3
22.97
21.14
%
0.25
17
168
13
70
1.93
1.28
3.2
5.8
25.05
24.62
mmol/l
0.18
13
70
58
458
1.42
1.27
5.2
4.7
3.07
1.88
ug/l
0.48
50
410
23
150
1.62
1.23
6.1
8.0
—
—
—
0
0
64
518
1.39
1.21
2.4
2.8
167.99
122.93
ug/l
0.72
55
480
38
280
1.47
1.19
1.4
1.7
0.86
1.12
mg/l
0.62
26
226
7
139
0.48
1.16
2.7
3.5
—
—
—
0
0
130
1192
1.50
1.15
4.6
4.6
1.73
1.91
mu/l
1.10
117
1081
7
32
2.24
1.09
1.3
1.6
—
—
—
0
0
7
32
2.24
1.09
1.3
1.6
—
—
—
0
0
53
425
1.37
1.04
3.6
3.6
2.32
2.35
mmol/l
0.54
40
380
5
22
2.31
1.04
1.2
1.6
—
—
—
0
0
134
1247
1.47
0.98
15.6
13.5
83.55
82.54
ml/min/173m2
0.26
114
1033
6
27
2.27
0.94
1.5
1.3
—
—
—
0
0
6
27
2.27
0.94
1.2
1.7
—
—
—
0
0
32
239
1.42
0.94
1.4
1.6
—
—
—
0
0
6
29
2.11
0.90
1.2
1.5
—
—
—
0
0
8
42
1.95
0.90
1.1
2.0
0.00
0.00
g/l
—
8
42
8
42
1.95
0.90
1.1
2.0
0.00
0.00
g/l
—
8
42
10
56
1.84
0.90
1.5
2.4
32.50
40.43
u/l
—
10
51
12
72
1.72
0.88
1.1
1.4
—
—
—
0
0
6
30
2.04
0.88
1.0
1.4
—
—
—
0
0
8
44
1.86
0.87
1.1
2.0
0.00
0.00
g/l
—
8
44
153
1478
1.93
0.87
23.0
20.3
134.66
136.93
g/l
1.37
153
1458
153
1476
1.97
0.86
23.0
20.2
39.57
40.70
%
1.28
147
1396
12
73
1.70
0.84
4.2
10.0
95.78
93.92
%
1.37
12
73
106
970
1.28
0.72
3.5
3.9
15.00
14.84
pmol/l
0.20
91
876
16
110
1.51
0.71
1.8
2.8
0.23
0.22
g/l
0.27
16
102
24
180
1.39
0.70
1.5
1.4
—
—
—
0
0
38
308
1.31
0.68
1.3
1.3
0.57
1.13
u/ml
—
7
92
49
412
1.27
0.67
2.1
2.5
52.57
70.55
u/l
0.85
44
385
5
30
1.69
0.62
1.0
1.3
—
—
—
0
0
19
140
1.41
0.62
2.2
1.9
283.53
366.87
nmol/l
1.64
19
129
8
51
1.60
0.61
1.3
2.4
—
—
—
0
0
6
38
1.60
0.55
1.2
1.8
—
—
—
0
0
9
62
1.48
0.54
1.4
3.2
0.78
1.16
%
—
9
62
10
66
1.55
0.54
1.0
1.0
—
—
—
0
0
34
282
1.26
0.52
2.1
2.1
3.62
3.01
mg/l
0.34
24
248
7
45
1.58
0.49
1.1
2.3
—
—
—
0
0
35
295
1.24
0.47
2.4
2.1
—
—
—
0
0
7
49
1.45
0.46
1.0
1.1
—
—
—
0
0
7
49
1.45
0.46
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
20
164
1.25
0.34
4.2
7.2
103.45
104.54
mmol/l
0.57
20
164
10
128
0.77
0.28
1.9
2.0
—
—
—
0
0
131
1273
1.17
0.26
4.5
4.4
6.08
5.91
mmol/l
0.39
115
1170
131
1274
1.16
0.25
4.5
3.9
1.23
1.32
mmol/l
0.96
114
1177
112
1158
0.89
0.24
20.7
17.0
14.52
14.84
%
0.27
112
1147
5
41
1.23
0.22
1.8
2.7
—
—
—
0
0
67
631
1.11
0.22
2.5
3.5
0.00
0.00
estimate
—
5
120
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
24
212
1.16
0.21
1.1
1.2
1.54
6.62
u/ml
—
7
87
12
144
0.82
0.21
2.0
2.1
—
—
—
0
0
11
133
0.81
0.20
1.8
1.7
—
—
—
0
0
8
71
1.13
0.16
1.0
1.3
—
—
—
0
0
9
79
1.15
0.15
1.2
1.2
—
134.66
—
0
28
132
1343
0.90
0.15
5.4
4.9
2.84
2.79
mmol/l
0.28
115
1250
36
385
0.92
0.14
2.9
3.7
6.18
8.99
mg/mmol
0.39
22
235
25
231
1.10
0.11
1.2
1.3
60.57
28.43
iu/ml
—
7
81
5
45
1.11
0.10
1.2
1.8
—
—
—
0
0
6
53
1.14
0.09
3.5
4.3
54.18
50.11
%
—
6
53
36
378
0.94
0.08
1.6
1.7
1.38
1.40
mmol/l
0.04
29
318
64
622
1.05
0.07
3.8
4.6
0.00
0.00
estimate
—
5
129
130
1314
0.94
0.06
5.0
4.4
1.49
1.44
mmol/l
0.52
115
1221
23
219
1.06
0.04
1.4
1.7
786.71
1204.52
nmol/l
1.85
14
165
132
1319
1.00
0.00
5.2
4.4
4.72
4.68
mmol/l
0.18
117
1235
57
569
1.00
0.00
2.5
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
4.5
—
85.83
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
7.96
—
0
7
0
7
0.00
-0.00
0.0
2.3
—
60.71
—
0
7
0
7
0.00
-0.00
0.0
1.6
—
34.17
—
0
7
5
53
0.94
-0.00
4.2
3.6
1780.20
307.89
u/ml
—
5
45
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
-0.00
0.0
3.2
—
113.40
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
13.53
—
0
7
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
122
1220
1.00
-0.00
5.5
5.4
40.06
39.74
mmol/mol
0.11
112
1148
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
70.21
—
0
7
0
5
0.00
-0.00
0.0
11.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_TICK_BORNE_ENCEPHALITIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_TICK_BORNE_ENCEPHALITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_TICK_BORNE_ENCEPHALITIS – Tick-borne viral encephalitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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