Presbycusis

H8_HL_PRESBY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H91.1
  • Hospital discharge: ICD-9 3880
  • Hospital discharge: excluded ICD-9 2880X
  • Cause of death: ICD-10 H91.1
  • Cause of death: ICD-9 3880
  • Cause of death: excluded ICD-9 2880X

2 out of 7 registries used, show all original rules.

5981

4. Check minimum number of events

None

5981

5. Include endpoints

None

5981

6. Filter based on genotype QC (FinnGen only)

5981

Control definitions (FinnGen only)

Control exclude
H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H91
Name in latin
Presbyacusis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 64425 38004 26033
Only index persons 55412 33250 22162
Unadjusted period prevalence (%)
Whole population 0.94 1.09 0.73
Only index persons 1.07 1.22 0.85
Median age at first event (years)
Whole population 80.01 81.05 78.51
Only index persons 79.56 80.63 77.95

-FinnGen-

Key figures

All Female Male
Number of individuals 5981 2765 3216
Unadjusted period prevalence (%) 1.20 0.94 1.42
Median age at first event (years) 76.72 76.80 76.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5284
Matched controls
52556
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
203.1
323.0
2522
235
H91.1
ICD-10 Finland
Presbycusis
4503599627370496.0
323.0
5280
907
R5120
NOMESCO Finland
Preparation of an aid
20.0
323.0
504
275
H02
ICPC
Hearing complaint
7.3
323.0
1504
2724
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
4.0
323.0
1933
6648
UDC00
NOMESCO Finland
Ear microscopy
13.2
323.0
900
806
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
71.4
323.0
785
128
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
30.8
323.0
604
219
SPAT1043
SPAT
Audiometry
7.8
323.0
1291
2102
DFF00
NOMESCO Finland
Pure tone audiometry
20.9
323.0
1085
641
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.8
323.0
1134
2354
DAX08
NOMESCO Finland
Fitting of hearing aid
33.6
323.0
701
238
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
32.9
323.0
1432
587
Z01.1
ICD-10 Finland
Examination of ears and hearing
15.0
323.0
1854
1830
DFF15
NOMESCO Finland
Speech audiometry
20.6
323.0
565
303
Z97.4
ICD-10 Finland
Presence of external hearing-aid
35.9
323.0
1142
400
H13
ICPC
Plugged feeling ear
3.6
279.6
1580
5609
R5140
NOMESCO Finland
Monitoring the use of the aid
5.5
251.9
822
1703
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
21.4
241.3
364
181
H91.9
ICD-10 Finland
Hearing loss, unspecified
11.7
238.9
461
424
H84
ICPC
Presbyacusis
7.3
195.8
503
751
H81
ICPC
Excessive ear wax
3.0
192.8
1356
5411
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
9.3
172.0
375
429
R4135
NOMESCO Finland
Rehabilitation for hearing problems
39.0
164.8
211
56
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.5
158.0
610
1475
H93.1
ICD-10 Finland
Tinnitus
10.6
144.6
291
286
A98
ICPC
Health maint/preventive medicine
2.4
144.4
4359
34654
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
130.5
142.6
153
12
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
82.1
141.8
160
20
N02BE01
ATC
paracetamol; systemic, rectal
2.4
137.0
4439
35882
H29
ICPC
Ear symptom/complaint other
3.5
134.7
714
2266
TDA90
NOMESCO Finland
Removal wax from ear
16.1
123.6
205
131
SPAT1263
SPAT
Sampling
2.0
121.9
2270
14214
SPAT1310
SPAT
Counselling related to known health issue
2.1
115.4
1704
9635
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.0
109.2
2249
14446
SPAT1301
SPAT
No procedures
1.9
92.5
1868
11703
R5599
NOMESCO Finland
Other rehabilitation service
5.9
91.6
268
468
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
80.4
91.2
103
13
J01DB01
ATC
cefalexin; oral
1.9
88.7
3785
30290
SPAT1312
SPAT
General health counselling
2.0
87.7
1510
8874
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
87.6
2705
19447
SPAT1325
SPAT
Vaccination
1.8
86.3
2130
14211
SPAT1153
SPAT
Removal of sutures
1.9
85.6
1689
10420
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
82.4
2365
16486
SPAT1260
SPAT
Consultation of another employee
2.2
81.8
1034
5332
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
81.1
1916
12523
Z97.8
ICD-10 Finland
Presence of other specified devices
83.7
81.1
91
11
N07CA01
ATC
betahistine; oral
3.0
78.4
493
1734
R1260
NOMESCO Finland
Evaluation of communicative skills
6.4
75.8
208
334
SPAT1097
SPAT
Recording of ECG
2.1
74.3
974
5080
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
8.2
73.6
170
212
-44
ICPC
Preventive immunization/medic
2.5
73.4
666
2914
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
71.6
1523
9518
-1
NOMESCO Finland
NA
1.9
70.9
1219
7062
SPAT1053
SPAT
Memory test
1.9
70.0
1279
7568
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
68.0
2278
16304
A02BC02
ATC
pantoprazole; systemic
1.7
66.9
3220
25445
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
46.8
64.5
79
17
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
136.9
63.9
68
5
H61.2
ICD-10 Finland
Impacted cerumen
3.1
62.8
380
1298
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
62.2
1232
7448
ZXA10
NOMESCO Finland
Bilateral
1.8
60.9
1190
7156
WX110
NOMESCO Finland
Local anesthesy
1.6
60.0
2651
20194
S18
ICPC
Laceration/cut
1.6
59.7
2053
14632
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
59.4
1622
10825
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.6
58.7
2267
16637
N40
ICD-10 Finland
Hyperplasia of prostate
1.7
55.4
1507
10001
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
54.8
1015
5964
P20
ICPC
Memory disturbance
1.8
53.9
1037
6168
SPAT1262
SPAT
Handing over of treatment supplies
1.8
53.1
1042
6235
RK520
NOMESCO Finland
NA
27.2
52.9
73
27
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
15.1
52.3
88
59
H28
ICPC
Limited function/disability (H)
9.0
52.2
113
127
AA1AD
NOMESCO Finland
CT of head and brain
1.7
51.6
1444
9621
R01AD09
ATC
mometasone; nasal
1.7
51.3
1520
10290
J01CA04
ATC
amoxicillin; systemic
1.6
51.2
3427
28399
R42
ICD-10 Finland
Dizziness and giddiness
1.7
50.8
1306
8483
SPAT1304
SPAT
Counselling and guidance related to ageing
2.1
50.2
631
3188
R05
ICPC
Cough
1.8
50.0
959
5677
H04
ICPC
Ear discharge
3.7
47.7
220
612
R01AD12
ATC
fluticasone furoate; nasal
1.9
45.1
800
4597
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
44.8
1595
11241
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
44.4
2366
18327
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
45.1
44.0
54
12
G04CA02
ATC
tamsulosin; oral
1.6
43.9
1578
11138
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
41.8
3472
29432
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.9
40.3
264
947
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
40.1
2038
15502
A44
ICPC
General and Unspecified, Preventive immunization/medic
2.3
39.8
414
1911
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.7
39.6
1055
6848
R02
ICPC
Shortness of breath/dyspnoea
1.9
39.6
668
3759
M79.6
ICD-10 Finland
Pain in limb
1.5
39.2
1524
10897
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
25.1
39.1
55
22
SPAT1131
SPAT
Colonoscopy
3.0
38.9
232
784
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
38.7
2235
17427
U04
ICPC
Incontinence urine
2.4
38.3
358
1570
Z01.9
ICD-10 Finland
Special examination, unspecified
2.5
38.3
312
1274
XKD00
NOMESCO Finland
Uroflowmetry
1.7
38.3
1014
6563
M01AH05
ATC
etoricoxib; oral
1.5
38.2
2025
15494
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
37.9
984
6334
M54.5
ICD-10 Finland
Low back pain
1.6
37.8
1280
8832
H01
ICPC
Ear pain/earache
2.3
37.7
357
1578
L08
ICPC
Shoulder symptom/complaint
1.7
37.6
825
5053
-69
ICPC
Other reason for encounter NEC
2.7
37.1
274
1059
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
36.9
1379
9736
ZXC50
NOMESCO Finland
Cryotherapy
2.7
36.2
267
1030
N17
ICPC
Vertigo/dizziness
1.8
35.8
631
3598
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
35.3
1019
6735
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.8
35.2
672
3932
L03
ICPC
Low back symptom/complaint
1.6
35.1
971
6343
RK320
NOMESCO Finland
NA
7.2
35.0
86
120
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.8
34.7
675
3973
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
34.2
1321
9372
L13
ICPC
Hip symptom/complaint
1.7
34.0
813
5095
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
33.9
3584
31125
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
3.0
33.1
199
676
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
33.1
1285
9115
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
32.7
1837
14092
RK420
NOMESCO Finland
NA
170.1
32.7
34
*
C07AB07
ATC
bisoprolol; oral
1.4
32.6
2857
23842
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
12.1
32.2
59
49
R06.0
ICD-10 Finland
Dyspnoea
1.5
32.2
1347
9705
M03BX02
ATC
tizanidine; oral
1.4
32.0
2014
15779
-31
ICPC
Medical examin/health eval partial
2.1
31.9
408
2059
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
31.9
1730
13163
R03AC02
ATC
salbutamol; inhalant
1.4
31.4
2109
16704
L12
ICPC
Hand/finger symptom/complaint
1.8
31.4
558
3180
A28
ICPC
Limited function/disability NOS
1.5
31.3
1160
8123
KMAK
NOMESCO Finland
NA
1.5
31.2
1661
12576
UKC02
NOMESCO Finland
Cystoscopy
1.6
30.4
1016
6931
G47.3
ICD-10 Finland
Sleep apnoea
1.7
29.9
677
4166
L17
ICPC
Foot/toe symptom/complaint
1.5
29.6
1120
7865
RK110
NOMESCO Finland
NA
6.3
29.6
80
128
S82
ICPC
Naevus/mole
1.9
29.6
490
2725
J01AA02
ATC
doxycycline; systemic
1.4
29.4
3542
31013
H26.4
ICD-10 Finland
After-cataract
1.7
29.4
730
4607
HMAK
NOMESCO Finland
NA
2.0
29.0
415
2189
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
29.0
1771
13724
G04BD12
ATC
mirabegron; oral
1.8
28.6
582
3464
SPAT1211
SPAT
Application of soft bandage
1.9
28.6
471
2612
C10AA01
ATC
simvastatin; oral
1.4
28.5
2704
22634
H92.0
ICD-10 Finland
Otalgia
3.2
28.5
152
476
L01
ICPC
Neck symptom/complaint
1.8
28.4
506
2885
H81.0
ICD-10 Finland
Ménière disease
4.1
28.3
112
274
D07AC01
ATC
betamethasone; topical
1.4
28.1
1479
11118
HAHOM
NOMESCO Finland
NA
6.8
27.9
71
105
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
27.6
870
5838
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
27.5
748
4831
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
9.1
27.5
58
64
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.8
27.4
465
2609
U02
ICPC
Urinary frequency/urgency
1.7
27.3
619
3799
SPAT1377
SPAT
Polysomnography
3.5
27.3
133
389
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
26.8
1204
8750
L15
ICPC
Knee symptom/complaint
1.6
26.8
864
5829
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.7
26.7
670
4232
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.7
26.6
565
3401
H02AB06
ATC
prednisolone; systemic
1.4
26.1
2159
17563
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.6
25.9
785
5212
A02BC05
ATC
esomeprazole; systemic
1.4
25.8
1725
13510
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
2.6
25.7
194
760
SPAT1041
SPAT
Comprehensive hearing test
5.3
25.4
79
151
SPAT1058
SPAT
PEF monitoring instruction
2.0
25.4
359
1883
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
25.2
1352
10160
H80.9
ICD-10 Finland
Otosclerosis, unspecified
10.9
25.2
48
44
M01AX05
ATC
glucosamine; oral
1.5
25.1
1181
8646
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
24.9
1783
14117
-51
ICPC
I&d/flush/aspiration
4.0
24.7
100
251
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
24.5
1726
13612
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
24.3
1381
10480
SPAT1252
SPAT
Overall medication plan or its review
1.8
24.1
446
2571
K02.1
ICD-10 Finland
Caries of dentine
1.4
24.1
1691
13319
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
24.0
1400
10670
M25.5
ICD-10 Finland
Pain in joint
1.5
24.0
921
6452
J01FA10
ATC
azithromycin; systemic
1.4
23.9
1811
14448
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
23.8
1656
13016
G04CA01
ATC
alfuzosin; oral
1.6
23.8
630
4030
M01AB05
ATC
diclofenac; systemic, rectal
1.3
23.8
2583
21827
D82
ICPC
Teeth/gum disease
1.5
23.8
932
6557
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
23.7
1106
8074
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
23.5
775
5238
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.8
23.4
436
2514
XJH00
NOMESCO Finland
Transanal ultrasonography
1.8
23.4
451
2631
R21
ICPC
Throat symptom/complaint
1.8
23.4
463
2724
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.8
23.3
450
2628
TDA90
SPAT
NA
3.3
23.2
122
379
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.7
23.2
479
2855
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
4.7
23.2
80
172
XCH00
NOMESCO Finland
Eye pressure measurement
2.2
23.1
242
1121
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
23.0
750
5056
RD211
NOMESCO Finland
NA
2.3
23.0
216
950
RK120
NOMESCO Finland
NA
13.9
22.9
39
28
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
22.6
1488
11560
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
10.0
22.6
45
45
S29
ICPC
Skin symptom/complaint other
1.6
22.5
732
4931
SDA02
NOMESCO Finland
Parodonthologic therapy
1.5
22.4
1011
7312
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
22.3
1656
13124
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.7
22.3
524
3246
L57.0
ICD-10 Finland
Actinic keratosis
1.6
22.2
652
4282
A02BC01
ATC
omeprazole; systemic
1.4
22.0
1459
11337
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
22.0
576
3671
C10AA05
ATC
atorvastatin; oral
1.3
22.0
1990
16275
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.3
21.9
201
876
S21
ICPC
Skin texture symptom/complaint
1.6
21.8
557
3530
A04
ICPC
Weakness/tiredness general
1.6
21.7
685
4579
R01AD01
ATC
beclometasone; nasal
1.6
21.7
545
3433
N03AX12
ATC
gabapentin; oral
1.6
21.7
627
4101
R05
ICD-10 Finland
Cough
1.5
21.6
780
5377
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.7
21.6
457
2745
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
21.5
879
6223
P06
ICPC
Sleep disturbance
1.9
21.5
316
1682
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
20.7
21.1
31
15
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
21.4
20.7
30
14
Z02.4
ICD-10 Finland
Examination for driving licence
1.4
20.6
1232
9382
E0000UV
ATC
NA
1.4
20.6
1582
12571
A02BC03
ATC
lansoprazole; oral
1.4
20.6
1410
10997
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
20.5
731
5023
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
20.5
1630
13024
R06AE07
ATC
cetirizine; oral
1.4
20.5
1502
11845
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
20.1
620
4117
R53
ICD-10 Finland
Malaise and fatigue
1.4
19.9
1097
8228
UJF32
NOMESCO Finland
Coloscopy
1.4
19.8
1222
9345
G04BD08
ATC
solifenacin; oral
1.7
19.7
399
2360
C08CA01
ATC
amlodipine; oral
1.3
19.7
2032
16867
B01AF02
ATC
apixaban; oral
1.6
19.6
611
4066
R74
ICPC
Upper respiratory infection acute
1.6
19.6
613
4081
J01MA02
ATC
ciprofloxacin; systemic
1.3
19.5
1934
15952
ZXC15
NOMESCO Finland
Use of photodynamic technique
2.9
19.3
122
431
Z00.0
ICD-10 Finland
General medical examination
1.5
19.3
792
5606
SPAT1094
SPAT
Continuous Positive Airway Pressure
4.7
19.2
65
138
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.7
19.2
436
2669
K86
ICPC
Hypertension uncomplicated
1.5
19.2
626
4209
207
Kela drug reimbursment
Chronic arrhythmias
1.4
19.2
1003
7444
R01AD08
ATC
fluticasone; nasal
1.4
19.1
870
6286
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
7.2
19.1
46
64
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
19.1
515
3303
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
19.1
648
4399
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.1
18.9
208
984
G04CB02
ATC
dutasteride; oral
1.7
18.7
390
2328
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
18.7
1272
9877
G44.2
ICD-10 Finland
Tension-type headache
1.7
18.7
411
2495
L16
ICPC
Ankle symptom/complaint
1.7
18.6
372
2191
H60.8
ICD-10 Finland
Other otitis externa
3.1
18.6
103
335
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
5.3
18.6
56
105
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.6
18.5
138
538
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
18.5
2505
21529
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.6
18.4
470
2972
K80
ICPC
Cardiac arrhythmia NOS
1.8
18.3
341
1967
H83.3
ICD-10 Finland
Noise effects on inner ear
6.3
18.2
48
76
WX723
NOMESCO Finland
CPAP therapy
3.0
18.1
105
352
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
18.1
850
6173
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
18.1
216
1061
B01AC04
ATC
clopidogrel; oral
1.4
18.1
989
7393
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
17.8
1633
13264
H65.3
ICD-10 Finland
Chronic mucoid otitis media
4.7
17.7
60
128
DFE00
NOMESCO Finland
Insertion of cochlear implant
+∞
17.7
17
*
C09CA01
ATC
losartan; oral
1.4
17.6
1197
9284
K30
ICD-10 Finland
Functional dyspepsia
1.7
17.5
378
2281
L14
ICPC
Leg/thigh symptom/complaint
1.7
17.4
354
2097
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
15.5
17.4
28
18
C09AA05
ATC
ramipril; oral
1.3
17.3
1484
11932
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
16.9
435
2757
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
16.8
343
2038
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
16.7
1008
7655
H91
ICD-10 Finland
Other hearing loss
4.8
16.6
55
115
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
16.6
949
7135
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
16.6
1150
8934
A03
ICPC
Fever
1.7
16.5
393
2435
WX720
NOMESCO Finland
Own respiration
2.3
16.5
153
672
B01AB05
ATC
enoxaparin; parenteral
1.3
16.4
1410
11319
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
16.3
1097
8477
R51.80
ICD-10 Finland
Headache
1.6
16.3
427
2717
H91.8
ICD-10 Finland
Other specified hearing loss
6.0
16.2
44
73
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
16.2
640
4485
WX320
NOMESCO Finland
Spinalanesthesy
1.4
16.1
1023
7828
SPAT1254
SPAT
Administration of medicine
1.4
16.1
798
5844
J31.0
ICD-10 Finland
Chronic rhinitis
2.0
16.0
215
1109
A97
ICPC
No disease
1.5
15.8
620
4332
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.6
15.7
423
2712
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
15.7
1741
14469
M01AC06
ATC
meloxicam; systemic, rectal
1.3
15.7
1406
11341
K85
ICPC
Elevated blood pressure
1.4
15.6
775
5671
Z71.8
ICD-10 Finland
Other specified counselling
1.4
15.6
811
5989
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
2.1
15.5
174
832
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
15.5
506
3395
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.6
15.4
423
2724
H60.3
ICD-10 Finland
Other infective otitis externa
3.2
15.4
79
245
F29
ICPC
Eye symptom/complaint other
1.7
15.1
298
1753
WX144
NOMESCO Finland
Subconjunctival anesthesy
2.7
15.0
101
371
AN1
HP
Coronary angiography
1.4
15.0
754
5532
M02AA07
ATC
piroxicam; topical
1.3
14.8
1760
14722
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
14.8
339
2077
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
14.8
430
2805
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.9
14.8
224
1209
K59.09
ICD-10 Finland
Constipation, unspecified
1.7
14.7
318
1920
R09
ICPC
Sinus symptom/complaint
2.0
14.6
179
891
D01BA02
ATC
terbinafine; oral; topical
1.4
14.4
958
7368
RK530
NOMESCO Finland
NA
149.5
14.4
15
*
S04
ICPC
Lump/swelling localized
1.7
14.4
336
2072
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.8
14.3
248
1398
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
14.3
915
6995
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
14.3
774
5753
R06.5
ICD-10 Finland
Mouth breathing
1.8
14.2
238
1328
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
11.3
14.2
26
23
C01DA14
ATC
isosorbide mononitrate; oral
1.3
14.2
1318
10656
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
2.5
14.2
109
437
U01
ICPC
Dysuria/painful urination
1.7
14.1
296
1772
R07
ICPC
Sneezing/nasal congestion
2.2
14.1
140
637
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.7
14.1
292
1743
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
14.1
811
6090
SPAT1359
SPAT
Use of symptom diary
2.4
14.0
116
483
-30
ICPC
Medical examin/health eval complete
2.2
13.9
141
647
RK290
NOMESCO Finland
NA
10.8
13.9
26
24
KED22
NOMESCO Finland
Transurethral resection of prostate
1.6
13.9
406
2657
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.5
13.8
505
3471
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.1
13.8
150
709
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
1.7
13.8
301
1822
C03CA01
ATC
furosemide; systemic
1.3
13.7
2252
19560
F03
ICPC
Eye discharge
1.9
13.6
192
1008
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
1.6
13.6
328
2042
XKC03
NOMESCO Finland
Water cystometry
2.1
13.5
146
690
F16
ICPC
Eyelid symptom/complaint
2.0
13.5
177
904
SPAT1351
SPAT
Extensive ear examination
5.3
13.5
40
75
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.5
13.4
533
3735
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.3
13.4
1000
7827
T16
ICD-10 Finland
Foreign body in ear
5.3
13.3
40
76
I50.9
ICD-10 Finland
Heart failure, unspecified
1.3
13.3
1158
9265
N06AX11
ATC
mirtazapine; oral
1.3
13.3
1249
10099
S02.51
ICD-10 Finland
Fracture of tooth, open
1.7
13.3
271
1610
T90
ICPC
Diabetes non-insulin dependent
1.3
13.3
1060
8372
L28
ICPC
Limited function/disability (L)
1.3
13.3
920
7113
K76
ICPC
Ischaemic heart dis without angina
2.1
13.2
155
760
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.0
13.1
159
789
D02
ICPC
Abdominal pain epigastric
1.9
13.1
190
1009
WX402
NOMESCO Finland
General anaesthesia
1.5
13.1
476
3273
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
13.1
1725
14569
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
13.0
765
5756
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.7
13.0
270
1613
Z00.8
ICD-10 Finland
Other general examinations
1.7
13.0
261
1542
M02AA10
ATC
ketoprofen; topical
1.4
12.9
684
5056
R55
ICD-10 Finland
Syncope and collapse
1.4
12.9
619
4494
H65.2
ICD-10 Finland
Chronic serous otitis media
4.2
12.9
48
115
N03AX16
ATC
pregabalin; oral
1.3
12.7
915
7113
XX3DW
NOMESCO Finland
Time consuming IT work
1.5
12.7
402
2676
A11
ICPC
Chest pain NOS
1.6
12.6
339
2172
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.4
12.6
545
3881
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.2
12.6
127
584
38699
ICD-8 Finland
NA
4.8
12.5
41
86
Z02.7
ICD-10 Finland
Issue of medical certificate
1.7
12.5
260
1553
DFX00
NOMESCO Finland
Connecting cochlear implant
+∞
12.5
12
*
R35
ICD-10 Finland
Polyuria
1.6
12.5
301
1876
R60.0
ICD-10 Finland
Localized oedema
1.4
12.4
561
4026
H40.0
ICD-10 Finland
Glaucoma suspect
1.6
12.4
350
2268
TFP20
NOMESCO Finland
Cardiodefibrillation
1.5
12.4
404
2712
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.4
12.4
673
4996
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
12.3
1318
10833
R96
ICPC
Asthma
1.6
12.2
327
2091
A54
ICPC
General and Unspecified, Repair/fix-suture/cast/prosth device
2.9
12.2
73
254
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
1.6
12.2
309
1952
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
12.1
933
7324
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.0
12.1
149
746
C05AA08
ATC
fluocortolone; rectal, topical
1.4
12.0
551
3965
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.4
12.0
507
3590
M01AX17
ATC
nimesulide; oral
1.3
12.0
1102
8867
N01
ICPC
Headache
1.7
12.0
238
1403
-54
ICPC
Repair/fix-suture/cast/prosth device
2.2
12.0
120
550
S06.0
ICD-10 Finland
Concussion
1.5
12.0
414
2814
S01EE01
ATC
latanoprost; ophthalmic
1.5
11.9
406
2749
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.3
11.9
843
6530
RK510
NOMESCO Finland
NA
10.0
11.9
23
23
F05
ICPC
Visual disturbance other
2.2
11.9
121
558
R44
ICPC
Respiratory, Preventive immunization/medic
2.4
11.8
97
404
SPAT1081
SPAT
Cardiorespiratory global assessment
1.6
11.8
296
1860
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
11.8
740
5623
XQ848
NOMESCO Finland
Dermatological photography
2.1
11.8
124
582
C10AA07
ATC
rosuvastatin; oral
1.3
11.8
961
7602
WZC30
NOMESCO Finland
Teaching
1.5
11.8
465
3249
K05
ICPC
Irregular heartbeat other
1.9
11.8
163
852
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.3
11.8
42
97
H03
ICPC
Tinnitus, ringing/buzzing ear
3.0
11.7
65
215
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
11.7
738
5619
S22.3
ICD-10 Finland
Fracture of rib
1.6
11.7
275
1704
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.6
11.6
333
2168
D01AE16
ATC
amorolfine; topical
1.4
11.6
502
3571
R04.0
ICD-10 Finland
Epistaxis
1.5
11.6
389
2626
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
11.6
1020
8154
D06
ICPC
Abdominal pain localized other
1.7
11.6
261
1596
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
11.6
266
1637
JAB30
NOMESCO Finland
Repair of inguinal hernia using prosthetic material
1.4
11.6
493
3501
J01FA09
ATC
clarithromycin; systemic
1.3
11.6
950
7522
Z51.88
ICD-10 Finland
Other specified medical care
2.2
11.5
111
498
WX780
NOMESCO Finland
Remote monitoring CPAP
2.4
11.5
95
398
J05AB01
ATC
aciclovir; systemic
1.3
11.5
758
5807
DFF16
NOMESCO Finland
Speech-in-noise audiometry
+∞
11.4
11
*
H91.0
ICD-10 Finland
Ototoxic hearing loss
+∞
11.4
11
*
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
11.4
11
*
SPAT1281
SPAT
Other administrative function
1.6
11.4
323
2096
I49.5
ICD-10 Finland
Sick sinus syndrome
1.6
11.4
282
1767
L90
ICPC
Osteoarthrosis of knee
1.6
11.4
279
1747
RK322
NOMESCO Finland
NA
13.5
11.4
19
14
D19
ICPC
Teeth/gum symptom/complaint
1.4
11.4
656
4913
D11
ICPC
Diarrhoea
1.6
11.4
305
1953
C09CA06
ATC
candesartan; oral
1.3
11.2
846
6615
N30.0
ICD-10 Finland
Acute cystitis
1.4
11.2
666
5018
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.5
11.1
435
3035
XF404
NOMESCO Finland
Ambulatory ECG
1.5
11.1
436
3043
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.0
11.1
135
673
A06AC51
ATC
ispaghula, combinations; systemic
1.8
11.1
205
1181
M47.82
ICD-10 Finland
Other spondylosis, cervical region
1.9
11.1
160
851
C08CA13
ATC
lercanidipine; oral
1.4
11.1
686
5202
A02BA02
ATC
ranitidine; systemic
1.3
11.1
1051
8481
R06AX27
ATC
desloratadine; oral
1.4
11.1
614
4572
ZXA05
NOMESCO Finland
Left side
1.3
11.1
1290
10686
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
11.0
566
4155
DC1AD
NOMESCO Finland
Temporalbone CT
6.4
11.0
28
44
H02.3
ICD-10 Finland
Blepharochalasis
1.6
11.0
274
1723
K22
ICPC
Risk factor cardiovascular disease
1.6
10.9
253
1558
VALMI
NOMESCO Finland
NA
1.4
10.9
650
4895
H66.9
ICD-10 Finland
Otitis media, unspecified
2.2
10.9
108
495
D01
ICPC
Abdominal pain/cramps general
1.5
10.9
329
2172
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
10.9
295
1895
SCA03
NOMESCO Finland
Preventive oral health care, extensive
2.1
10.8
121
584
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
10.8
1120
9142
TPH07
NOMESCO Finland
Cathetrisation of artery
1.4
10.7
489
3515
S01
ICPC
Pain/tenderness of skin
1.8
10.7
169
928
D12
ICPC
Constipation
1.8
10.7
180
1008
D07AC13
ATC
mometasone; topical
1.3
10.7
1082
8802
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
11.1
10.5
19
17
L05
ICPC
Flank/axilla symptom/complaint
1.7
10.5
210
1244
R31
ICD-10 Finland
Unspecified haematuria
1.4
10.5
545
4013
H27
ICPC
Fear of ear disease
3.7
10.4
44
119
K78
ICPC
Atrial fibrillation/flutter
1.4
10.4
504
3667
H25.8
ICD-10 Finland
Other senile cataract
1.3
10.3
718
5540
SPAT1291
SPAT
Other function in accordance with NCSP classification
2.5
10.3
78
313
I95.1
ICD-10 Finland
Orthostatic hypotension
1.6
10.3
235
1443
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.4
10.3
545
4027
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
10.3
919
7350
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
0.5
10.3
81
1579
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
10.3
635
4812
DDA00
NOMESCO Finland
Stapedotomy
8.1
10.2
22
27
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
1.4
10.2
608
4583
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.5
10.2
380
2626
R15
ICD-10 Finland
Faecal incontinence
2.0
10.1
129
655
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.2
10.1
1685
14513
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.7
10.0
190
1106
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
1.6
10.0
272
1750
SPAT1059
SPAT
Spirometry at the office
1.7
10.0
204
1217
H71
ICD-10 Finland
Cholesteatoma of middle ear
3.6
10.0
43
119
H51
ICPC
Ear, I&d/flush/aspiration
2.5
10.0
74
292
M01AE02
ATC
naproxen; oral, rectal
1.2
9.9
1968
17244
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.4
9.9
457
3292
N02AX02
ATC
tramadol; systemic, rectal
1.2
9.9
1848
16094
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.3
9.9
697
5388
Z75.9
ICD-10 Finland
Unspecified problem related to medical facilities and other health care
5.3
9.9
29
55
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
9.8
686
5297
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.7
9.8
64
237
H80
ICD-10 Finland
Otosclerosis
25.9
9.8
13
5
R06AE09
ATC
levocetirizine; oral
1.5
9.8
354
2434
ZXA00
NOMESCO Finland
Right side
1.2
9.8
1348
11361
-60
ICPC
Result test/procedure
1.6
9.7
278
1813
L04
ICPC
Chest symptom/complaint
1.7
9.7
201
1205
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.3
9.6
658
5058
S06
ICPC
Rash localized
1.6
9.6
222
1369
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.4
9.6
460
3336
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
9.6
840
6692
S02
ICPC
Pruritus
1.9
9.6
130
679
D21
ICPC
Swallowing problem
2.5
9.6
72
287
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
9.5
1076
8858
H61.8
ICD-10 Finland
Other specified disorders of external ear
3.2
9.5
47
145
S22
ICPC
Nail symptom/complaint
1.6
9.5
227
1412
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
9.5
194
1159
-45
ICPC
Observ/health educat/advice/diet
1.9
9.5
129
675
SPAT1216
SPAT
Assessment of functional ability
1.3
9.5
835
6658
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.3
9.5
636
4879
H70.1
ICD-10 Finland
Chronic mastoiditis
7.1
9.4
22
31
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.2
9.4
11
489
M48.0
ICD-10 Finland
Spinal stenosis
1.3
9.4
624
4777
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.3
9.4
22
683
RK111
NOMESCO Finland
NA
99.6
9.4
10
*
R01AD11
ATC
triamcinolone; nasal
1.6
9.4
259
1673
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
1.9
9.4
124
642
T92
ICPC
Gout
2.1
9.4
101
480
J01EA01
ATC
trimethoprim; systemic
1.2
9.4
1261
10592
YHMAS
NOMESCO Finland
NA
4.4
9.4
32
72
3882A
ICD-9 Finland
Other disorders of ear, Sudden hearing loss, unspecified
+∞
9.4
9
*
SPAT1118
SPAT
Haemorrhoid procedure
4.9
9.3
29
59
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
1.5
9.3
344
2373
-50
ICPC
Medication/prescr/renewal
1.7
9.3
200
1213
G04BD09
ATC
trospium; oral
1.9
9.2
139
754
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.6
9.2
224
1403
114
Kela drug reimbursment
Glaucoma
1.3
9.2
589
4487
WX704
NOMESCO Finland
Intubation
1.6
9.1
228
1438
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
2.1
9.1
95
448
Z01.2
ICD-10 Finland
Dental examination
1.3
9.1
1082
8956
WX002
NOMESCO Finland
Sedation and analgesia
1.3
9.1
862
6940
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
9.0
779
6194
S97
ICPC
Chronic ulcer skin
1.5
9.0
278
1845
R52.9
ICD-10 Finland
Pain, unspecified
1.5
9.0
294
1974
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
9.0
905
7336
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.2
9.0
1501
12893
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
1.5
9.0
285
1904
AN2
HP
Balloon angioplasty, including several vessels
1.7
9.0
166
962
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
8.9
312
2125
SPAT1044
SPAT
Tympanometry
2.7
8.9
58
215
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
8.9
403
2892
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
1.7
8.9
174
1026
-35
ICPC
Urine test
2.6
8.8
60
227
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
1.6
8.8
242
1565
N39.3
ICD-10 Finland
Stress incontinence
1.6
8.8
251
1637
L18
ICPC
Muscle pain
1.8
8.8
139
768
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.6
8.8
252
1643
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
8.8
616
4757
S01BC05
ATC
ketorolac; ophthalmic
1.5
8.7
282
1892
R75
ICPC
Sinusitis acute/chronic
2.1
8.7
97
470
R13
ICD-10 Finland
Dysphagia
1.5
8.7
277
1853
XKD03
NOMESCO Finland
Urethral pressure profilometry
2.0
8.7
108
548
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.4
8.7
350
2459
P01AB01
ATC
metronidazole; oral, rectal
1.2
8.7
1356
11561
R11
ICD-10 Finland
Nausea and vomiting
1.4
8.6
352
2477
WX290
NOMESCO Finland
Other blockade of nerve
1.3
8.6
915
7467
SPAT1229
SPAT
Assessment of need for aid
1.4
8.6
423
3082
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.8
8.6
147
833
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.4
8.6
363
2573
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
8.6
883
7178
J01DA01
ATC
[U] cefalexin; systemic
1.2
8.6
2675
24340
EBA10
NOMESCO Finland
Surgical removal of tooth
1.6
8.5
229
1472
Y85
ICPC
Benign prostatic hypertrophy
2.2
8.5
83
381
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
3.0
8.5
46
153
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
8.4
175
1050
K02
ICPC
Pressure/tightness of heart
2.0
8.4
108
554
H70
ICPC
Otitis externa
2.5
8.4
63
254
M01AH02
ATC
rofecoxib; oral
1.3
8.4
625
4864
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
8.4
381
2737
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
4.2
8.4
30
71
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.4
8.4
416
3037
R08
ICPC
Nose symptom/complaint other
2.1
8.4
94
458
F02
ICPC
Red eye
1.8
8.4
141
797
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.0
8.3
105
535
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
8.3
706
5602
S15
ICPC
Foreign body in skin
1.6
8.3
228
1475
F70
ICPC
Conjunctivitis infectious
2.4
8.3
64
262
RK321
NOMESCO Finland
NA
10.7
8.2
15
14
F06.7
ICD-10 Finland
Mild cognitive disorder
1.7
8.2
151
876
A10BB01
ATC
glibenclamide; oral
0.7
8.2
201
2959
D17
ICPC
Incontinence of bowel
2.8
8.2
49
173
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.8
8.2
136
764
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
8.2
438
3238
R32
ICD-10 Finland
Unspecified urinary incontinence
1.8
8.2
134
751
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
2.0
8.2
104
533
H82
ICPC
Vertiginous syndrome
2.2
8.2
80
366
J02AC01
ATC
fluconazole; systemic
1.2
8.1
1125
9457
H40.11
ICD-10 Finland
Low pressure glaucoma
1.9
8.1
116
619
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.7
8.1
148
857
A29
ICPC
General symptom/complaint other
1.3
8.1
501
3794
K96
ICPC
Haemorrhoids
2.2
8.1
80
370
R03BA08
ATC
ciclesonide; inhalant
1.6
8.0
224
1451
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.4
8.0
467
3503
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.4
8.0
468
3510
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
7.9
795
6437
H01.0
ICD-10 Finland
Blepharitis
1.7
7.9
144
832
S16
ICPC
Bruise/contusion
1.7
7.9
144
833
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.9
809
6567
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.0
7.9
93
463
W10
ICD-10 Finland
Fall on and from stairs and steps
1.6
7.9
191
1200
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
2.2
7.8
76
349
H71
ICPC
Acute otitis media/myringitis
4.2
7.8
28
67
F01
ICPC
Eye pain
2.1
7.8
80
373
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
1.7
7.8
167
1012
K07
ICPC
Swollen ankles/oedema
1.5
7.8
241
1604
H60
ICD-10 Finland
Otitis externa
1.9
7.8
105
551
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.5
7.7
242
1612
EBA00
NOMESCO Finland
Extraction of tooth
1.2
7.7
1028
8599
C10AA03
ATC
pravastatin; oral
1.4
7.7
386
2824
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
7.7
538
4151
I21.9
ICD-10 Finland
Acute myocardial infarction, unspecified
0.5
7.7
64
1222
J30.0
ICD-10 Finland
Vasomotor rhinitis
2.1
7.7
80
380
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.4
7.6
307
2155
L29
ICPC
Musculoskeletal sympt/complt other
1.5
7.6
286
1982
S70.0
ICD-10 Finland
Contusion of hip
1.6
7.6
198
1263
H05
ICPC
Bleeding ear
4.2
7.6
27
64
F21
ICPC
NA
2.2
7.6
72
327
XKX00
NOMESCO Finland
Pelvic floor electromyography
5.5
7.6
21
38
A06AD11
ATC
lactulose; oral
1.2
7.6
960
7983
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.6
516
3962
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
1.5
7.6
271
1860
R21
NOMESCO Finland
Counselling and guidance in rehabilitation
3.2
7.6
37
115
D40
ICPC
Digestive, Diagnostic endoscopy
4.3
7.6
26
60
XF402
NOMESCO Finland
ECG with work load test
1.3
7.5
477
3625
G04BD11
ATC
fesoterodine; oral
1.7
7.5
156
938
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
1.5
7.5
242
1624
D12
ICD-10 Finland
Benign neoplasm of colon, rectum, anus and anal canal
4.5
7.5
25
56
RK220
NOMESCO Finland
NA
5.1
7.5
22
43
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
3.0
7.5
40
133
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.5
570
4451
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
1.6
7.4
185
1169
R81
ICPC
Pneumonia
1.8
7.4
131
752
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
1.6
7.4
175
1093
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.6
7.4
206
1336
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.5
7.3
278
1933
S01.0
ICD-10 Finland
Open wound of scalp
1.4
7.3
333
2397
SPAT1251
SPAT
Organisation of medication
1.6
7.3
205
1332
SPAT1098
SPAT
Exercise ECG
2.0
7.3
88
441
TQW80
NOMESCO Finland
Local dermatologic skincare
1.9
7.3
105
564
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
7.3
167
1034
3891A
ICD-9 Finland
Deafness, Sensorineural deafness
+∞
7.3
7
*
H81.2
ICD-10 Finland
Vestibular neuronitis
2.2
7.2
66
294
N04BC05
ATC
pramipexole; oral
1.4
7.2
310
2207
R05FB02
ATC
cough suppressants and expectorants
1.2
7.2
1712
15134
JN3AD
NOMESCO Finland
Abdominal CT examination
1.4
7.2
286
2007
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.6
7.2
158
969
S08
ICPC
Skin colour change
1.6
7.2
199
1292
R03DC03
ATC
montelukast; oral
1.3
7.2
430
3244
H31
ICPC
Ear, Medical examin/health eval partial
7.2
7.1
16
22
G04BD07
ATC
tolterodine; oral
1.4
7.1
303
2150
H53.1
ICD-10 Finland
Subjective visual disturbances
1.6
7.1
186
1189
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.5
7.1
203
1326
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
7.1
626
4983
H03AA01
ATC
levothyroxine sodium; systemic
1.2
7.1
909
7566
U05
ICPC
Urination problems other
1.5
7.1
224
1497
EMAK
NOMESCO Finland
NA
1.9
7.1
103
556
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.1
1608
14158
R03BA05
ATC
fluticasone; inhalant
1.3
7.1
619
4925
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.4
7.0
292
2063
H81.3
ICD-10 Finland
Other peripheral vertigo
1.9
7.0
97
514
D16
ICPC
Rectal bleeding
2.0
7.0
82
408
A10
ICPC
Bleeding/haemorrhage NOS
2.8
7.0
42
151
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.5
7.0
250
1717
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.6
6.9
49
192
J01CA08
ATC
pivmecillinam; oral
1.2
6.9
1603
14126
I25
ICD-10 Finland
Chronic ischaemic heart disease
1.4
6.9
278
1954
SPAT1234
SPAT
Support of social functional capacity
1.4
6.9
274
1923
J45.1
ICD-10 Finland
Nonallergic asthma
1.5
6.9
261
1812
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.3
6.9
639
5120
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
3.6
6.9
29
81
A08
ICPC
Swelling
1.5
6.8
196
1287
H80.1
ICD-10 Finland
Otosclerosis involving oval window, obliterative
9.3
6.7
13
14
WX400
NOMESCO Finland
Inhalation anesthesy
1.8
6.7
106
587
SPAT1101
SPAT
Orthostatic test
1.4
6.7
256
1782
DFX03
SPAT
NA
39.8
6.7
8
*
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
2.7
6.7
41
149
H53.9
ICD-10 Finland
Visual disturbance, unspecified
1.9
6.7
94
500
H25.0
ICD-10 Finland
Senile incipient cataract
1.4
6.7
316
2288
TKD00
NOMESCO Finland
Dilatation of urethra
2.6
6.7
47
183
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.3
6.7
12
418
B02.9
ICD-10 Finland
Zoster without complication
1.5
6.7
239
1643
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.4
6.6
292
2088
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.3
6.6
716
5847
L86
ICPC
Back syndrome with radiating pain
1.5
6.6
185
1203
B01AF01
ATC
rivaroxaban; oral
1.3
6.6
531
4178
SPAT1039
SPAT
Otomicroscopy
2.4
6.6
51
212
S70
ICPC
Herpes zoster
1.8
6.6
101
556
J00
ICD-10 Finland
Acute nasopharyngitis [common cold]
2.9
6.6
36
123
B01AA03
ATC
warfarin; systemic
1.2
6.6
1435
12578
S09
ICPC
Infected finger/toe
1.8
6.6
108
607
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
1.7
6.5
133
798
G03CA04
ATC
estriol; systemic, vaginal
1.3
6.5
479
3725
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
1.6
6.5
167
1066
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.4
6.5
336
2472
J01FA06
ATC
roxithromycin; oral
1.2
6.5
1588
14049
N06AX21
ATC
duloxetine; oral
1.4
6.5
283
2023
UDM02
NOMESCO Finland
Sinoscopy
2.2
6.5
61
278
B81
ICPC
Anaemia vit B12/folate deficiency
1.5
6.5
197
1309
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.6
6.4
160
1013
A02BC04
ATC
rabeprazole; oral
1.5
6.4
222
1515
N05CF01
ATC
zopiclone; oral
1.2
6.4
1633
14488
M10.9
ICD-10 Finland
Gout, unspecified
1.4
6.4
311
2263
F92
ICPC
Cataract
2.6
6.4
42
159
W19
ICD-10 Finland
Unspecified fall
1.3
6.4
401
3048
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
6.4
599
4811
R03BA01
ATC
beclometasone; inhalant
1.3
6.4
554
4402
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.4
6.4
276
1969
S10
ICPC
Boil/carbuncle
1.6
6.4
167
1072
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.4
601
4827
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
1.7
6.3
114
662
A01
ICPC
Pain general/multiple sites
1.4
6.3
307
2235
K59.1
ICD-10 Finland
Functional diarrhoea
1.5
6.3
194
1290
F13
ICPC
Eye sensation abnormal
1.9
6.3
85
448
N35.9
ICD-10 Finland
Urethral stricture, unspecified
2.2
6.3
58
263
H92.2
ICD-10 Finland
Otorrhagia
8.1
6.3
13
16
-40
ICPC
Diagnostic endoscopy
4.4
6.3
21
48
L92
ICPC
Shoulder syndrome
2.0
6.3
78
397
SPAT1016
SPAT
Examination of vision
1.5
6.3
171
1110
N05AD01
ATC
haloperidol; systemic
0.6
6.3
69
1215
ACC51
NOMESCO Finland
Release of median nerve
1.5
6.3
201
1354
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.3
6.3
373
2809
A51
ICPC
General and Unspecified, I&d/flush/aspiration
5.5
6.3
17
31
WNF00
NOMESCO Finland
Infection source and contact determination
3.4
6.3
28
83
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
2.1
6.2
65
311
K04.0
ICD-10 Finland
Pulpitis
1.6
6.2
135
824
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.8
6.2
102
575
H91.3
ICD-10 Finland
Deaf mutism, not elsewhere classified
+∞
6.2
6
*
SPAT1054
SPAT
Examination of peripheral nervous system
2.0
6.2
69
337
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.3
6.2
357
2676
XX2VW
NOMESCO Finland
Radiologic consultation
3.7
6.2
25
68
R07.0
ICD-10 Finland
Pain in throat
1.7
6.2
131
794
S01ED51
ATC
timolol, combinations; ophthalmic
1.3
6.2
438
3385
H74.1
ICD-10 Finland
Adhesive middle ear disease
7.0
6.2
14
20
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
1.6
6.2
154
978
R29
ICPC
Respiratory symptom/complaint other
1.5
6.2
180
1184
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
2.3
6.2
53
230
R33
ICD-10 Finland
Retention of urine
1.3
6.2
454
3532
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
1.6
6.1
160
1027
4148X
ICD-9 Finland
Other forms of chronic ischaemic heart disease, Other specified forms of chronic ischaemic heart disease[MORBUS CORDIS ISCHAEMICUS ALIA,MÄÄRITTELEMÄT]
0.4
6.1
18
497
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
6.1
501
3957
C09CA03
ATC
valsartan; oral
1.3
6.1
383
2911
Z50.0
ICD-10 Finland
Cardiac rehabilitation
2.1
6.1
63
299
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.6
6.1
137
849
S61.0
ICD-10 Finland
Open wound of finger(s) without damage to nail
1.5
6.1
194
1304
A01AB09
ATC
miconazole; local oral
1.3
6.1
402
3081
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.3
6.1
353
2653
K01
ICPC
Heart pain
2.0
6.0
70
349
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.5
6.0
189
1265
L11
ICPC
Wrist symptom/complaint
1.5
6.0
211
1448
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.3
6.0
460
3596

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
4258
30575
2.34
187.40
24.5
23.6
14.0
14.1
%
5.39
4112
29667
929
3589
2.86
167.06
5.4
4.6
—
—
—
0
0
4925
39028
2.45
151.51
21.7
18.3
—
—
—
0
0
1860
10288
2.16
150.25
4.6
4.3
—
—
—
0
0
5032
40371
2.51
148.62
24.3
22.7
89.0
86.8
umol/l
3.42
5032
40345
4918
39148
2.41
146.23
20.4
19.2
26.1
29.0
mg/l
8.27
4222
32870
5093
41201
2.55
145.61
25.3
23.2
139.3
139.4
mmol/l
1.39
4945
39819
5096
41248
2.55
145.31
25.7
23.4
4.0
4.0
mmol/l
0.26
4939
39789
4067
30242
2.06
140.93
6.1
5.6
1806.0
2376.0
e6/l
0.35
124
569
5109
41586
2.53
140.54
30.1
27.7
30.4
30.4
pg
0.60
4993
40446
5110
41598
2.53
140.53
30.3
27.9
7.2
7.1
e9/l
0.35
4913
39671
5109
41588
2.53
140.49
30.2
27.8
92.1
92.0
fl
0.59
4993
40446
5109
41588
2.53
140.49
30.2
27.9
4.3
4.3
e12/l
2.06
4903
39657
5108
41584
2.52
140.28
30.2
27.9
230.9
237.9
e9/l
11.43
4937
39886
5109
41596
2.52
140.28
30.5
28.1
129.1
129.4
g/l
0.79
4990
40471
4972
40184
2.37
135.50
11.7
11.1
23.0
23.5
u/l
0.70
4605
38012
4576
35782
2.16
135.18
6.8
6.8
41.9
41.6
mmol/mol
1.41
3832
31940
3984
29773
1.99
131.17
5.4
5.0
—
—
—
0
0
3066
21006
1.93
130.66
15.4
11.7
1.3
1.4
inr
2.51
1275
5538
969
4311
2.48
128.92
4.2
3.8
1.2
1.2
mmol/l
0.44
764
3705
4492
35142
2.09
128.53
5.2
4.8
2.1
2.1
mu/l
0.27
3741
30902
4646
37017
2.11
123.38
5.4
5.1
6.1
6.2
mmol/l
0.78
3618
32222
2670
17713
1.90
123.10
13.5
10.4
0.0
0.0
e9/l
0.22
2199
14190
2357
15055
1.92
121.64
4.3
3.8
7.4
7.4
ph
2.16
675
2764
3825
28610
1.92
120.26
5.2
4.6
—
—
—
0
0
4619
36909
2.08
118.87
5.5
5.3
2.4
2.5
mmol/l
9.45
3679
32547
4485
35470
2.03
118.67
4.8
4.6
4.2
4.3
mmol/l
7.40
3660
31374
3913
29579
1.91
117.97
4.6
4.2
16.2
16.5
mm/h
0.53
3358
26628
4222
32733
1.96
117.86
7.4
7.3
82.6
83.4
u/l
0.32
3818
30343
4417
35014
1.98
112.28
4.8
4.6
1.4
1.4
mmol/l
3.47
3483
30711
3123
22233
1.83
111.02
5.6
5.7
1.2
1.2
mmol/l
3.87
2703
19835
1524
8618
2.02
110.31
3.8
3.5
—
—
—
0
0
3776
28630
1.85
107.81
4.2
3.9
15.2
15.2
pmol/l
0.16
3090
25044
3363
24670
1.81
106.45
6.2
6.3
1.2
1.2
mmol/l
3.40
2470
20453
4273
33812
1.90
104.97
4.1
4.1
1.2
1.2
mmol/l
3.03
3323
29249
3561
26721
1.81
102.95
4.7
4.7
6.9
7.0
mmol/l
0.79
3384
25011
1777
10831
1.90
101.81
1.9
1.7
7315517.7
16042031.9
pmol/l
0.53
1203
8559
2916
20731
1.78
100.34
4.6
4.4
0.0
0.0
estimate
0.50
908
3748
2888
20485
1.78
100.07
4.5
4.3
0.0
0.0
estimate
0.00
927
3825
4137
32728
1.84
97.58
22.8
21.6
37.2
37.2
%
0.15
2105
19057
2870
20470
1.76
96.23
5.7
5.9
0.0
0.0
estimate
0.00
911
3764
1550
9206
1.91
95.02
1.6
1.6
1.3
1.3
mmol/l
0.54
958
7584
1806
11278
1.85
94.55
4.9
4.8
0.0
0.0
estimate
0.34
864
3560
1772
11091
1.84
91.53
3.0
2.8
5.5
5.3
e6/l
0.31
1539
9719
2502
17352
1.75
90.97
2.3
2.2
82.0
80.4
nmol/l
1.86
2043
14786
2696
19167
1.73
89.10
5.0
4.4
89.0
90.6
ng/l
0.02
2179
15304
2254
15608
1.70
79.33
3.8
3.6
222.8
95.1
e6/l
0.93
1788
12147
1979
13472
1.69
72.68
2.5
2.5
61.2
59.4
u/l
0.34
1752
12274
2420
17365
1.65
72.44
4.4
4.1
147.9
149.3
e6/l
0.02
1854
12772
336
1158
3.00
72.36
2.7
2.5
16.0
15.7
%
0.64
170
602
1243
7450
1.83
71.17
4.8
4.4
—
—
—
0
0
2438
17651
1.63
69.59
3.4
3.2
2287.8
2291.8
ng/l
0.01
1999
15400
2195
15516
1.64
68.73
6.0
5.6
7.6
5.0
ug/l
0.44
1749
13482
2331
16791
1.62
67.26
3.1
2.9
168.5
155.3
ug/l
0.42
1921
14967
2565
18956
1.61
66.29
5.5
5.5
2.7
2.8
%
0.55
2314
17260
1975
13693
1.65
66.17
3.7
3.5
—
—
—
0
0
2572
19034
1.60
65.99
5.8
5.8
9.1
9.0
%
0.58
2323
17381
2510
18502
1.60
65.24
5.5
5.5
0.6
0.6
%
0.05
2265
16874
637
3119
2.15
64.97
3.9
3.6
0.5
0.3
%
0.30
161
826
2591
19329
1.59
63.46
5.6
5.7
24.7
24.6
%
0.15
2320
17539
2025
14283
1.62
62.48
3.7
3.5
0.6
0.6
e6/l
0.10
1591
10983
327
1206
2.80
62.10
3.9
4.5
2.6
2.9
mmol/l
1.10
200
844
2028
14331
1.62
61.97
5.0
5.2
—
—
—
0
0
2997
23203
1.57
61.96
5.4
5.7
12.8
12.7
umol/l
0.11
2796
21815
327
1208
2.79
61.90
3.9
4.5
4.9
5.0
kpa
3.45
321
1167
327
1210
2.79
61.71
3.9
4.5
8.4
8.2
kpa
1.21
321
1168
2540
18963
1.58
61.33
5.3
5.5
60.0
59.9
%
0.17
2276
17303
263
872
3.09
60.50
2.0
1.9
1.6
1.7
mmol/l
0.22
258
852
2367
17496
1.57
58.99
3.9
3.7
—
—
—
0
0
1568
10550
1.65
57.54
3.1
2.9
512.2
544.9
mosm/kgh2o
9.52
1333
8912
622
3170
2.06
56.75
3.8
3.5
0.5
0.6
%
0.39
147
755
671
3556
1.99
54.83
3.9
3.6
0.9
0.9
%
0.07
177
1093
646
3379
2.01
54.78
4.0
3.6
0.1
0.1
%
0.04
171
1019
1766
12413
1.59
53.42
5.3
4.8
22.5
22.5
%
0.04
884
6790
1816
12859
1.58
53.17
1.7
1.6
20.2
19.7
nmol/l
0.57
1423
10935
2664
20559
1.52
52.66
5.2
5.3
0.2
0.2
e9/l
0.02
2289
17325
339
1386
2.52
52.29
3.9
4.3
7.4
7.4
ph
1.23
322
1167
1716
12040
1.59
52.04
2.0
1.8
1212.9
1163.7
nmol/l
1.18
1163
8773
2578
19873
1.51
50.52
5.1
5.1
0.7
0.6
e9/l
2.21
2139
16502
2590
20001
1.51
50.23
5.1
5.2
0.0
0.0
e9/l
0.49
2153
16652
2076
15387
1.52
48.45
4.5
4.3
—
—
—
0
0
2677
20935
1.49
48.11
3.1
3.1
59.0
57.9
u/l
0.15
2298
18534
2615
20355
1.49
48.08
5.2
5.3
1.9
1.9
e9/l
0.04
2253
17171
1983
14601
1.53
47.50
2.2
2.1
214.9
223.6
u/l
0.20
1808
13493
1886
13747
1.53
47.31
2.4
2.3
3.0
3.2
mg/l
3.58
1502
11530
2722
21443
1.48
46.67
4.5
4.4
33.9
33.9
g/l
0.11
2388
19438
300
1225
2.51
46.35
3.7
3.7
—
—
—
0
0
2922
23490
1.46
44.29
7.5
8.0
4.6
4.5
e9/l
0.48
2506
19960
1290
8815
1.58
42.38
3.6
3.3
0.9
0.9
ug/l
0.11
860
6523
1151
7721
1.60
40.71
2.6
2.5
2.2
2.2
g/l
0.16
1007
7008
1220
8308
1.58
40.43
2.6
2.5
11.5
11.3
umol/l
0.55
1097
7516
290
1243
2.39
40.28
2.6
2.2
127.1
125.4
g/l
0.59
254
924
1100
7329
1.60
39.94
2.7
2.6
21.2
20.4
%
1.28
868
6154
2154
16635
1.45
38.58
3.0
3.2
2.3
2.4
mmol/l
1.43
1786
13974
2638
21174
1.43
38.17
2.2
2.2
92.0
91.2
pmol/l
0.37
1253
10781
114
334
3.44
32.16
1.6
1.5
—
—
—
0
0
198
797
2.52
31.53
3.6
3.4
56.6
60.0
%
2.67
198
797
1541
11562
1.44
30.66
3.1
3.0
38.7
37.7
u/l
0.14
1396
10756
1422
10522
1.45
30.45
4.8
4.3
263.4
465.1
ng/l
1.34
1307
9401
511
2976
1.77
30.39
5.2
5.8
24.5
25.0
mmol/l
2.04
505
2935
1486
11166
1.43
29.06
2.8
2.9
4840.7
8063.2
umol/l
1.82
1131
9225
293
1443
2.07
28.93
4.7
5.2
1.4
1.4
mmol/l
0.03
243
1277
1207
8751
1.47
28.48
1.6
1.6
1.5
1.6
mg/l
0.34
902
6861
802
5347
1.57
28.17
1.3
1.2
—
—
—
0
0
829
5617
1.54
27.02
3.7
3.1
260.7
296.2
ng/l
1.56
758
5140
1968
15689
1.37
26.68
2.4
2.3
—
—
—
0
0
929
6486
1.50
26.25
1.3
1.2
1.6
1.6
u/ml
0.04
204
1496
1731
13613
1.37
25.24
3.3
3.1
582.9
357.6
mg/l
0.89
1022
8731
212
971
2.22
25.23
3.4
2.4
1.9
1.9
mg/l
0.10
180
842
1713
13477
1.37
24.83
4.6
4.6
—
—
—
0
0
2359
19508
1.34
24.57
4.6
4.3
—
—
—
0
0
165
687
2.43
24.50
4.1
9.7
7.2
7.5
mmol/l
0.50
135
565
610
3959
1.59
23.85
1.3
1.3
—
—
—
0
0
1067
7798
1.44
23.62
1.8
1.9
30.4
30.3
s
0.46
1017
7519
282
1477
1.94
23.43
2.8
3.2
25.0
25.1
mmol/l
0.11
262
1285
233
1148
2.06
23.00
2.7
2.8
—
—
—
0
0
1712
13623
1.35
22.63
3.3
3.1
6.4
6.7
mmol/l
1.64
1223
11009
820
5742
1.49
22.58
1.7
1.4
2.7
2.8
g/l
0.59
431
3031
170
747
2.30
22.37
3.5
2.6
—
—
—
0
0
953
6896
1.45
22.12
2.5
2.2
1.8
1.8
%
0.22
797
5910
254
1321
1.95
21.55
2.6
2.9
7.8
7.7
kpa
0.49
241
1228
722
5048
1.48
19.88
3.0
2.4
66.9
67.9
e9/l
0.31
532
3756
204
1012
2.04
19.80
5.2
5.8
104.6
105.0
mmol/l
0.47
179
900
204
1012
2.04
19.80
5.2
5.8
11.4
11.2
mmol/l
0.38
179
900
510
3316
1.58
19.67
1.9
2.1
380.3
388.4
nmol/l
0.35
463
2952
732
5172
1.46
19.07
1.3
1.3
50.9
43.0
iu/ml
0.44
240
1580
1765
14447
1.31
18.33
4.4
3.8
10.9
10.4
mg/mmol
0.16
960
9083
770
5549
1.44
18.01
1.4
1.4
—
—
—
0
0
163
781
2.11
17.41
3.6
3.1
—
—
—
0
0
252
1413
1.81
16.98
1.2
1.2
157.3
266.8
u/ml
3.41
221
1273
396
2571
1.57
15.33
3.5
2.6
10.4
11.0
g/l
1.31
349
2300
327
2029
1.64
15.29
2.3
1.8
1.7
1.4
g/l
0.62
279
1771
362
2306
1.60
15.20
1.9
1.8
3.6
2.7
ug/l
0.34
311
1950
362
2334
1.58
14.45
2.9
2.9
—
—
—
0
0
1007
7848
1.33
14.36
2.6
2.7
0.8
0.8
mmol/l
0.84
899
7097
461
3159
1.49
13.90
3.3
3.7
7.4
7.4
ph
0.75
141
420
660
4855
1.40
13.56
1.2
1.2
11.8
16.6
u/ml
0.89
200
1589
400
2675
1.52
13.55
7.4
7.9
—
—
—
0
0
464
3201
1.48
13.52
3.3
3.7
5.1
5.2
kpa
0.86
426
2914
244
1452
1.70
13.42
2.9
3.0
—
—
—
0
0
131
647
2.04
13.00
1.2
1.3
—
—
—
0
0
551
3972
1.42
12.70
2.3
2.3
—
—
—
0
0
418
2866
1.48
12.56
1.5
1.6
—
—
—
0
0
298
1919
1.57
11.99
2.9
2.9
1.4
3.3
ratio
1.22
23
144
474
3363
1.44
11.92
5.1
5.9
24.5
24.5
mmol/l
0.07
432
3134
304
1972
1.56
11.85
3.0
2.9
46.5
61.5
mg/l
0.59
198
1609
120
595
2.03
11.82
2.3
2.4
—
—
—
0
0
77
320
2.41
11.69
2.6
2.6
—
—
—
0
0
304
1979
1.56
11.67
3.0
2.9
58.7
87.1
mg/l
0.48
199
1614
192
1119
1.73
11.44
1.2
1.2
2.3
1.0
u/ml
0.44
16
104
549
4041
1.39
11.19
1.3
1.3
448.3
491.7
titre
0.30
145
926
70
285
2.46
11.13
1.3
1.3
—
—
—
0
0
461
3307
1.42
10.91
2.0
1.8
172.6
182.5
ug/g
0.20
322
2495
159
893
1.79
10.78
1.3
1.4
—
—
—
0
0
557
4141
1.37
10.67
1.4
1.4
—
—
—
0
0
1118
9181
1.26
10.35
4.6
5.0
1.0
1.0
kg/l
0.10
233
1605
491
3610
1.38
10.07
3.7
4.0
—
—
—
0
0
383
2700
1.44
9.99
2.5
2.5
—
—
—
0
0
316
2147
1.49
9.97
4.4
4.3
0.9
0.9
%
1.99
286
2025
569
4294
1.35
9.90
1.9
1.9
0.2
0.2
g/l
1.08
494
3891
299
2039
1.48
9.28
1.3
1.3
—
—
—
0
0
315
2173
1.47
9.22
4.4
4.3
1.7
1.5
%
1.61
288
2046
620
4797
1.32
9.09
2.6
2.4
65.4
65.7
g/l
0.51
528
4198
1247
10511
1.23
8.97
3.1
3.2
2.5
2.5
mmol/l
0.36
1039
8942
63
271
2.33
8.95
2.1
2.1
2.0
2.7
u/field
0.35
36
184
828
6683
1.27
8.77
5.3
4.9
1.0
1.0
mmol/l
0.47
743
6009
699
5535
1.29
8.62
5.4
6.0
95.2
95.0
%
0.34
657
5300
97
514
1.89
8.03
1.2
1.4
56.5
65.1
%
1.02
52
329
64
291
2.20
8.03
2.4
2.0
479.9
504.6
min
0.82
38
203
622
4914
1.29
7.79
2.4
2.5
9.3
10.4
umol/l
0.54
505
4200
771
6296
1.25
7.34
5.4
5.7
1.3
1.1
mmol/l
0.43
580
4813
528
4116
1.30
7.32
3.4
3.4
106.9
97.4
ng/l
1.11
381
3397
196
1299
1.52
7.07
1.5
1.5
—
—
—
0
0
311
2251
1.40
7.06
1.2
1.2
—
—
—
0
0
59
277
2.13
6.89
1.1
1.1
—
—
—
0
0
65
321
2.03
6.66
1.2
1.3
11.8
12.3
u/l
0.10
50
253
45
192
2.34
6.61
1.8
2.5
1745.3
1751.3
ml
0.01
37
154
789
6556
1.23
6.37
1.8
1.9
—
—
—
0
0
310
2285
1.37
6.33
1.2
1.2
—
—
—
0
0
60
295
2.03
6.25
1.9
1.9
317.3
331.2
mu/l
0.17
52
273
759
6298
1.23
6.21
5.5
5.7
11.3
11.6
kpa
1.07
703
5896
641
5225
1.25
6.18
1.9
1.8
—
—
—
0
0
759
6301
1.23
6.18
5.5
5.7
5.0
5.1
kpa
1.30
702
5905
609
4942
1.25
6.11
6.0
6.4
117.6
118.4
g/l
0.42
573
4769
67
346
1.94
6.09
1.7
1.7
5.3
4.9
mg/l
0.27
61
320
1069
9219
1.19
5.81
1.4
1.3
—
—
—
0
0
24
80
2.99
5.73
1.5
1.1
0.3
2.6
mmol/l
1.59
15
48
141
915
1.55
5.68
1.5
1.4
0.2
0.2
g/l
0.42
133
858
66
349
1.89
5.62
2.1
2.2
7.4
7.4
ph
0.23
29
123
21
66
3.17
5.53
1.6
1.1
95.8
588.6
u/l
0.49
13
44
3233
30286
1.13
5.46
28.1
26.0
330.3
329.9
g/l
2.01
3206
29732
482
3872
1.26
5.30
1.4
1.3
—
—
—
0
0
57
293
1.94
5.30
1.5
1.4
—
—
—
0
0
163
1112
1.47
5.21
3.6
3.9
31.5
31.5
mg/l
0.00
120
766
61
325
1.88
5.11
1.8
1.6
—
—
—
0
0
51
256
1.99
5.09
3.1
1.7
8.5
9.2
mmol/l
0.77
38
212
141
939
1.51
5.08
1.5
1.4
1.1
1.2
g/l
0.95
134
878
254
1883
1.36
5.07
1.3
1.2
—
—
—
0
0
29
115
2.52
5.05
1.1
1.1
—
—
—
0
0
46
887
0.51
5.03
2.2
2.6
4.0
4.1
mmol/l
0.92
46
881
267
2001
1.34
4.97
1.9
2.0
10.8
10.4
nmol/l
0.29
200
1674
46
876
0.52
4.85
2.2
2.6
—
—
—
0
0
251
1877
1.34
4.76
3.6
3.0
4.4
4.3
pmol/l
0.98
211
1594
52
271
1.92
4.69
1.5
1.2
—
—
—
0
0
77
458
1.68
4.51
1.8
1.5
0.5
0.9
g/l
2.68
43
341
51
270
1.89
4.41
1.5
1.2
0.3
0.5
g/l
3.74
25
191
51
270
1.89
4.41
1.5
1.2
5.5
7.3
g/l
2.33
26
189
51
270
1.89
4.41
1.5
1.2
2.3
3.0
g/l
2.27
26
189
247
1867
1.33
4.38
2.3
2.4
37.8
29.4
au/ml
—
7
36
35
164
2.13
4.24
1.4
1.4
37.6
33.1
iu/l
0.32
29
136
114
1662
0.68
4.17
4.1
4.7
—
—
—
0
0
106
697
1.52
4.13
1.6
1.6
4.0
4.1
iu/l
0.05
38
195
17
58
2.92
3.96
1.1
1.2
17.7
16.6
g/l
0.27
17
52
234
1795
1.31
3.79
3.5
3.3
0.8
0.8
nmol/l
1.25
191
1394
297
2352
1.27
3.76
3.4
3.4
4.5
4.4
e9/l
0.13
189
1600
25
108
2.31
3.70
1.5
1.1
1.7
1.5
mmol/l
0.38
16
65
65
392
1.66
3.68
1.2
1.4
38.3
26.4
%
1.13
29
250
945
8354
1.15
3.66
3.5
3.2
3.3
2.6
e6/l
0.70
507
4656
198
1492
1.33
3.65
1.1
1.1
98.9
136.1
iu/ml
0.69
61
469
567
4832
1.18
3.53
6.1
5.7
12.5
12.1
mmol/l
0.52
520
4495
25
111
2.25
3.50
1.1
1.1
1.1
1.1
ratio
—
9
30
29
137
2.11
3.49
1.2
1.4
—
—
—
0
0
73
460
1.59
3.49
1.5
1.3
273.3
274.8
mosm/kgh2o
0.21
61
312
383
3152
1.22
3.46
3.7
3.6
—
—
—
0
0
13
41
3.16
3.46
1.2
1.3
—
—
—
0
0
144
1053
1.37
3.27
3.0
2.4
—
—
—
0
0
644
5596
1.16
3.17
3.5
3.7
13.0
28.2
ug/l
2.27
519
4651
1263
11486
1.12
3.11
3.6
4.0
79.8
81.0
%
0.98
1220
11203
6
8
7.47
3.04
1.7
1.5
250.2
217.7
nmol/l
—
6
8
329
2709
1.22
3.00
1.5
1.4
—
—
—
0
0
41
232
1.76
2.98
1.1
1.2
2.1
2.2
mmol/l
0.30
41
211
20
88
2.27
2.89
1.1
1.1
—
—
—
0
0
20
88
2.27
2.89
1.1
1.1
—
—
—
0
0
20
88
2.27
2.89
1.1
1.1
—
—
—
0
0
20
89
2.24
2.83
1.3
1.3
—
—
—
0
0
65
424
1.53
2.75
2.5
2.2
701.3
632.3
ml
0.56
38
264
140
1051
1.33
2.74
1.4
1.3
60.7
60.7
mmol/l
0.00
114
830
90
628
1.43
2.74
1.2
1.3
41.5
28.7
e6/l
0.14
73
497
90
628
1.43
2.74
1.3
1.4
2356.7
1045.3
e6/l
0.35
80
523
82
565
1.45
2.67
1.2
1.3
—
—
—
0
0
206
1637
1.26
2.64
1.3
1.3
77.6
64.5
au/ml
0.21
11
67
222
1782
1.25
2.61
2.4
2.1
—
—
—
0
0
19
86
2.20
2.60
1.3
1.3
0.1
0.1
nmol/l
—
9
63
32
177
1.80
2.55
1.1
1.1
—
—
—
0
0
326
2733
1.20
2.52
3.5
2.9
0.3
0.4
e6/l
1.01
313
2685
113
835
1.35
2.49
1.3
1.4
—
—
—
0
0
132
1001
1.32
2.45
2.8
2.8
395.4
744.7
u/ml
0.48
114
923
40
240
1.66
2.42
1.1
1.0
—
—
—
0
0
58
381
1.52
2.42
1.4
1.3
—
—
—
0
0
316
2653
1.20
2.41
1.4
1.6
—
—
—
0
0
160
1251
1.28
2.37
1.4
1.4
283.0
256.9
ug/g
0.81
92
786
73
505
1.44
2.37
1.4
1.3
11.5
13.9
u/l
0.72
63
468
37
219
1.69
2.36
6.9
3.9
—
—
—
0
0
14
58
2.40
2.34
1.1
1.1
—
—
—
0
0
15
65
2.30
2.28
8.6
9.7
14.2
13.8
%
0.47
15
65
42
260
1.61
2.27
1.3
1.2
—
—
—
0
0
548
4832
1.14
2.25
5.0
5.4
1.3
1.4
mmol/l
1.46
519
4596
11
41
2.67
2.25
11.5
14.7
—
—
—
0
0
48
308
1.55
2.24
2.3
1.8
—
—
—
0
0
29
163
1.77
2.23
1.4
1.3
3.8
2.2
u/ml
0.28
17
93
24
127
1.88
2.22
1.5
1.3
59.3
78.1
umol/l
0.55
11
74
74
521
1.42
2.21
2.4
2.4
2.4
2.2
u/field
0.07
34
163
39
239
1.63
2.20
6.6
3.7
—
—
—
0
0
16
73
2.18
2.18
1.2
1.1
—
—
—
0
0
106
799
1.33
2.10
1.2
1.1
188.3
114.4
titre
0.31
12
48
341
2923
1.17
2.08
1.5
1.4
—
—
—
0
0
22
116
1.89
2.07
1.7
1.8
—
—
—
0
0
55
372
1.48
2.05
1.1
1.1
33.8
34.3
mmol/l
0.07
45
292
6
15
3.98
2.03
1.0
1.2
520.8
239.3
nmol/l
—
6
15
307
2619
1.18
2.00
1.5
1.4
—
—
—
0
0
153
1219
1.26
2.00
1.3
1.3
—
—
—
0
0
18
90
1.99
1.97
1.6
1.4
—
—
—
0
0
152
1213
1.25
1.96
2.7
2.2
115.0
88.4
ug/min
0.37
90
704
58
401
1.44
1.95
1.5
1.3
—
—
—
0
0
58
401
1.44
1.95
1.5
1.3
—
—
—
0
0
58
401
1.44
1.95
1.5
1.3
—
—
—
0
0
58
401
1.44
1.95
1.5
1.3
—
—
—
0
0
199
1639
1.22
1.92
1.2
1.2
—
—
—
0
0
26
149
1.74
1.91
1.3
1.3
15.6
9.1
umol/l
0.31
16
95
106
813
1.30
1.89
2.0
2.2
60.6
59.5
%
0.19
106
807
16
78
2.04
1.88
1.3
3.0
—
—
—
0
0
70
506
1.38
1.85
2.6
2.1
—
—
—
0
0
133
1054
1.26
1.84
1.2
1.2
—
—
—
0
0
21
114
1.84
1.84
1.1
1.2
39.2
30.3
%
0.35
12
75
15
72
2.08
1.83
3.1
3.0
0.3
0.6
u/field
0.66
15
72
10
40
2.49
1.81
1.1
1.3
—
—
—
0
0
69
502
1.37
1.77
1.3
1.2
—
—
—
0
0
104
805
1.29
1.75
1.4
1.3
—
—
—
0
0
335
2917
1.15
1.71
1.9
1.6
1.5
1.6
g/l
0.61
261
2483
59
421
1.40
1.70
1.3
1.3
209.5
253.1
pmol/l
0.97
44
323
71
526
1.35
1.65
1.2
1.1
—
—
—
0
0
8
31
2.57
1.64
1.0
1.1
—
—
—
0
0
106
831
1.27
1.64
4.2
3.6
0.9
1.5
%
1.73
86
605
34
219
1.55
1.64
1.1
1.2
—
—
—
0
0
43
292
1.47
1.63
1.3
1.2
—
—
—
0
0
407
4537
0.88
1.63
2.4
2.9
4.3
4.3
kpa
0.07
391
4352
104
817
1.27
1.59
1.2
1.2
70.8
40.5
u/l
0.49
92
693
46
319
1.44
1.57
1.3
1.2
—
—
—
0
0
62
455
1.36
1.54
1.3
1.3
32.5
59.1
mu/l
1.74
51
402
951
8830
1.08
1.53
3.3
3.0
1.1
1.3
e6/l
1.68
520
5087
111
885
1.25
1.52
1.9
2.0
27.9
32.8
umol/l
1.69
80
701
66
491
1.34
1.51
1.3
1.2
297.7
331.9
nmol/l
0.80
59
374
28
176
1.59
1.51
5.6
5.5
—
—
—
0
0
41
282
1.45
1.48
1.1
1.3
—
—
—
0
0
11
212
0.52
1.41
1.8
2.4
—
—
—
0
0
58
431
1.34
1.37
1.1
1.1
—
—
—
0
0
101
1235
0.81
1.31
1.2
1.2
—
—
—
0
0
33
224
1.47
1.30
1.6
1.9
11.4
13.2
%
0.40
12
87
102
823
1.24
1.30
1.2
1.1
1298.0
1169.0
titre
—
5
20
24
152
1.57
1.29
1.4
1.3
19.6
24.7
%
0.48
19
120
134
1115
1.20
1.27
2.4
2.5
—
—
—
0
0
73
569
1.28
1.25
1.8
1.9
—
—
—
0
0
58
438
1.32
1.25
1.1
1.1
—
—
—
0
0
29
194
1.49
1.23
1.2
1.2
1.4
1.0
promille
0.68
19
144
480
5208
0.91
1.22
2.2
2.4
5.1
6.3
ug/l
1.80
375
4307
15
85
1.76
1.21
1.0
1.1
0.6
0.6
umol/24h
—
7
34
27
393
0.68
1.19
1.0
1.1
1.2
655.7
iu/ml
—
5
68
43
313
1.37
1.18
9.1
13.4
—
—
—
0
0
31
213
1.45
1.17
1.1
1.1
2.6
15.9
nmol/l
—
8
48
48
631
0.75
1.15
1.3
1.3
1.0
0.8
nmol/l
0.45
42
510
108
892
1.21
1.13
1.1
1.1
—
—
—
0
0
61
472
1.29
1.13
1.1
1.0
—
—
—
0
0
43
316
1.36
1.13
1.6
1.7
—
—
—
0
0
23
150
1.53
1.12
1.2
1.0
—
—
—
0
0
57
438
1.30
1.11
1.4
1.3
122.8
121.0
u/ml
0.04
22
80
92
750
1.22
1.10
1.3
1.3
—
—
—
0
0
20
127
1.57
1.09
1.7
1.8
—
—
—
0
0
52
398
1.30
1.06
1.2
1.1
287.8
308.2
u/ml
0.18
28
237
12
67
1.78
1.03
7.3
9.7
—
—
—
0
0
46
349
1.31
1.01
1.2
1.2
2.7
4.1
u/ml
1.19
16
170
38
280
1.35
1.00
1.2
1.1
95.0
130.7
titre
—
6
55
38
280
1.35
1.00
1.2
1.1
—
126.4
—
0
11
1500
14349
1.05
1.00
2.6
2.6
—
—
—
0
0
31
221
1.40
1.00
2.3
2.3
—
—
—
0
0
65
517
1.25
1.00
1.4
1.2
—
—
—
0
0
50
385
1.29
0.99
1.4
1.2
—
—
—
0
0
53
412
1.28
0.98
1.6
1.3
201.0
436.3
titre
—
10
52
11
61
1.80
0.97
29.7
29.2
6.3
6.9
ug/l
0.54
11
53
24
164
1.46
0.96
1.2
1.1
—
—
—
0
0
29
206
1.40
0.96
1.4
1.2
1.2
1.1
nmol/l
0.22
22
156
72
583
1.23
0.95
1.4
1.4
—
—
—
0
0
7
37
1.88
0.93
1.1
1.3
—
—
—
0
0
512
5463
0.93
0.93
3.1
3.5
1.6
2.0
mmol/l
1.20
408
4398
44
339
1.29
0.89
2.0
1.9
2.3
2.1
ug/l
0.23
38
285
6
29
2.06
0.89
1.2
1.3
—
—
—
0
0
8
42
1.90
0.88
1.0
1.0
—
—
—
0
0
256
2306
1.11
0.88
2.5
2.2
3.7
3.8
g/l
0.31
171
1642
21
143
1.46
0.87
1.0
1.1
—
—
—
0
0
38
288
1.31
0.86
1.1
1.0
—
—
—
0
0
52
414
1.25
0.83
1.3
1.3
—
—
nmol/l
—
0
0
15
96
1.56
0.82
1.5
2.4
—
—
—
0
0
8
46
1.73
0.82
1.4
1.2
—
—
—
0
0
212
1900
1.11
0.81
2.1
2.2
562.8
594.9
ug/l
0.08
197
1793
146
1644
0.88
0.80
2.9
3.7
3.9
3.9
mmol/l
0.10
116
1512
31
231
1.34
0.80
5.5
4.6
246.8
101.6
u/ml
0.37
11
59
89
752
1.18
0.80
1.3
1.2
29.3
4.1
u/ml
0.51
12
70
517
5476
0.93
0.80
3.1
3.4
5.8
5.8
kpa
0.29
496
5279
15
97
1.54
0.79
1.2
1.3
—
—
—
0
0
37
473
0.78
0.79
1.8
1.5
—
—
—
0
0
125
1086
1.15
0.79
1.2
1.2
—
—
—
0
0
6
33
1.81
0.78
3.0
3.6
—
—
—
0
0
7
121
0.58
0.77
1.1
1.2
14.7
15.0
g/l
—
7
89
205
1841
1.11
0.77
2.6
2.1
36.8
36.5
g/l
0.27
164
1519
13
82
1.58
0.76
1.0
1.0
0.2
0.7
u/ml
—
7
31
242
2194
1.10
0.76
2.5
2.2
10.5
10.4
g/l
0.09
191
1800
50
402
1.24
0.75
2.9
3.2
—
—
—
0
0
24
174
1.37
0.74
1.1
1.1
130.0
133.9
nmol/l
0.22
24
174
259
2809
0.91
0.74
3.7
4.0
—
—
—
0
0
7
38
1.83
0.73
1.1
1.0
—
—
—
0
0
16
108
1.48
0.72
1.3
1.3
—
—
—
0
0
24
320
0.75
0.71
1.7
1.7
—
—
—
0
0
7
40
1.74
0.71
3.4
4.5
—
—
—
0
0
12
76
1.57
0.70
1.2
1.4
—
—
—
0
0
48
388
1.23
0.70
1.7
1.5
—
—
—
0
0
49
397
1.23
0.70
1.7
1.3
72.0
46.5
titre
—
5
26
42
335
1.25
0.69
1.1
1.1
—
—
—
0
0
15
101
1.48
0.68
1.3
1.3
140.0
152.9
nmol/l
—
9
70
264
2847
0.92
0.68
2.6
3.3
25.0
25.1
mmol/l
0.19
244
2771
84
719
1.16
0.68
1.2
1.2
—
—
—
0
0
900
8595
1.05
0.67
29.2
32.3
1.7
1.6
inr
1.34
88
1125
12
77
1.55
0.67
1.0
1.1
0.2
0.8
u/ml
—
5
33
376
3995
0.93
0.66
3.2
3.8
—
—
—
0
0
22
161
1.36
0.66
1.2
1.3
—
—
—
0
0
54
446
1.21
0.65
1.4
1.3
—
—
—
0
0
73
847
0.86
0.65
1.4
1.4
82619.5
59346.9
e6/l
0.17
41
501
448
4722
0.94
0.63
4.1
4.7
—
—
—
0
0
27
206
1.31
0.63
1.3
1.3
166.0
334.7
ug/l
0.35
13
119
20
146
1.36
0.62
3.4
2.7
—
—
—
0
0
16
112
1.42
0.62
1.7
1.4
10.0
8.6
ug/l
0.16
11
98
8
50
1.59
0.61
6.5
8.6
—
—
—
0
0
155
1698
0.91
0.58
3.0
4.1
110.9
87.3
u/ml
0.17
145
1607
6
35
1.71
0.57
1.0
1.1
1.6
1.7
umol/24h
—
6
35
19
140
1.35
0.56
1.6
1.4
—
—
—
0
0
239
2562
0.93
0.56
2.3
2.4
0.7
0.7
%
0.13
229
2467
29
228
1.27
0.56
1.2
1.1
—
3.3
iu/ml
—
0
9
188
1717
1.09
0.56
3.3
3.6
—
—
—
0
0
36
291
1.23
0.56
1.6
1.8
1.0
1.0
e9/l
0.12
30
187
113
1007
1.12
0.54
1.4
1.5
30.8
30.6
g/l
0.04
97
876
8
122
0.65
0.54
1.1
1.1
—
—
—
0
0
20
260
0.76
0.54
2.2
1.5
—
—
—
0
0
71
809
0.87
0.53
1.4
1.5
—
—
—
0
0
1054
10812
0.96
0.52
2.5
2.5
—
—
—
0
0
6
99
0.60
0.51
1.3
1.1
—
—
—
0
0
12
83
1.44
0.50
1.4
1.3
32.4
83.8
mu/l
—
6
62
32
259
1.23
0.50
1.4
1.6
—
—
—
0
0
33
269
1.22
0.49
1.2
1.5
70.5
68.1
%
0.16
28
211
10
67
1.49
0.48
1.1
1.1
—
—
—
0
0
72
631
1.14
0.47
5.2
5.7
12.1
12.8
mg/l
0.60
66
558
27
331
0.81
0.47
1.7
1.4
—
—
—
0
0
52
599
0.86
0.47
3.8
3.3
—
—
—
0
0
22
276
0.79
0.47
1.1
1.3
—
—
—
0
0
53
456
1.16
0.45
1.1
1.1
—
—
—
0
0
19
146
1.30
0.45
2.7
2.1
—
—
—
0
0
7
51
1.37
0.43
1.1
1.1
—
—
—
0
0
25
201
1.24
0.43
1.2
1.5
60.5
65.7
mg/l
0.20
12
139
443
4217
1.05
0.43
2.4
2.3
35.4
37.5
u/l
0.38
350
3542
8
55
1.45
0.42
1.4
1.2
—
—
—
0
0
46
394
1.16
0.42
1.3
1.2
—
—
—
0
0
15
113
1.32
0.41
1.6
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.0
—
0
6
58
508
1.14
0.40
1.2
1.1
—
—
—
0
0
143
1316
1.08
0.40
9.7
12.6
—
—
—
0
0
29
240
1.20
0.39
1.7
1.7
—
35.6
—
0
23
54
472
1.14
0.39
1.0
1.0
—
—
—
0
0
178
1656
1.07
0.39
3.0
2.7
0.3
0.3
g/l
0.01
65
630
98
889
1.10
0.38
2.0
1.7
12.4
12.5
mg/l
0.05
89
809
5
36
1.38
0.38
2.8
2.5
1.9
1.1
mg/l
—
5
28
18
142
1.26
0.37
1.3
1.4
—
—
—
0
0
68
607
1.12
0.36
1.2
1.2
—
—
—
0
0
14
179
0.78
0.36
2.3
2.5
44.3
37.1
%
—
8
68
15
116
1.29
0.36
1.3
1.4
18.9
16.6
pmol/l
—
9
88
34
393
0.86
0.35
1.1
1.2
—
—
—
0
0
41
464
0.88
0.32
1.8
1.7
—
—
—
0
0
310
2956
1.05
0.31
6.9
7.2
24.4
24.4
mmol/l
0.06
278
2674
10
74
1.34
0.31
1.2
1.3
11.4
7.5
mg/l
—
10
68
7
52
1.34
0.31
1.7
1.1
—
—
—
0
0
12
92
1.30
0.31
1.2
1.2
339.3
264.3
pmol/l
—
6
69
7
96
0.73
0.30
1.3
1.1
—
—
—
0
0
7
97
0.72
0.30
1.3
1.1
—
—
—
0
0
7
98
0.71
0.30
1.3
1.1
—
—
—
0
0
7
99
0.70
0.30
1.3
1.1
—
—
—
0
0
22
183
1.20
0.30
1.3
1.1
0.7
0.9
u/ml
—
5
64
61
550
1.10
0.29
1.0
1.1
—
—
—
0
0
28
323
0.86
0.29
3.5
3.2
—
—
—
0
0
10
75
1.33
0.29
1.0
1.3
—
—
—
0
0
17
138
1.23
0.29
1.1
1.1
—
—
—
0
0
223
2116
1.05
0.29
3.5
4.2
—
—
—
0
0
77
709
1.08
0.25
1.4
1.5
—
—
—
0
0
11
86
1.27
0.25
1.7
1.5
98.5
128.8
ng/l
0.58
11
86
25
286
0.87
0.25
1.1
1.1
—
93.2
—
0
13
40
443
0.90
0.25
1.1
1.2
—
—
—
0
0
17
141
1.20
0.25
1.1
1.1
—
—
—
0
0
9
75
1.19
0.24
1.3
1.1
—
—
—
0
0
44
395
1.11
0.24
1.1
1.1
1.4
1.6
g/l
2.05
34
353
15
123
1.21
0.24
1.4
1.6
3.7
6.0
%
—
9
60
18
151
1.19
0.24
1.1
1.2
46.9
38.8
g/l
—
6
72
5
37
1.34
0.23
7.4
5.2
—
—
—
0
0
46
502
0.91
0.22
2.5
2.7
—
—
—
0
0
5
41
1.21
0.22
1.4
1.2
26.4
163.8
ng/l
—
5
21
86
911
0.94
0.21
1.4
1.4
1220.7
1820.8
e6/l
0.97
70
639
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
2340.9
—
0
11
14
166
0.84
0.21
1.2
1.1
—
—
—
0
0
43
390
1.10
0.21
1.2
1.4
—
—
—
0
0
0
13
0.00
0.20
0.0
1.1
—
0.0
—
0
6
0
13
0.00
0.20
0.0
2.4
—
11.8
—
0
8
0
13
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
355.2
—
0
14
16
186
0.86
0.20
1.1
1.1
—
—
—
0
0
17
145
1.17
0.19
2.1
1.7
—
—
—
0
0
121
1148
1.05
0.19
1.5
1.6
—
—
—
0
0
185
1774
1.04
0.18
4.1
4.2
24.6
24.9
mmol/l
0.61
157
1566
116
1102
1.05
0.17
1.4
1.5
16066.0
16336.5
e6/l
0.02
88
775
83
782
1.06
0.17
1.6
1.6
—
—
—
0
0
5
66
0.75
0.17
1.4
1.1
—
—
—
0
0
10
82
1.21
0.16
1.6
1.1
—
—
—
0
0
269
2610
1.03
0.15
1.4
1.4
—
—
—
0
0
28
305
0.91
0.15
2.2
2.7
6.9
7.2
mmol/l
0.41
20
217
17
149
1.14
0.14
1.2
1.7
7262.8
20327.9
e6/l
—
6
87
7
85
0.82
0.14
1.3
1.0
—
—
—
0
0
7
86
0.81
0.14
3.0
2.5
—
—
—
0
0
24
216
1.11
0.14
1.1
1.1
—
—
—
0
0
44
409
1.07
0.14
1.1
1.3
396604.0
179053.8
e6/l
0.40
19
278
1027
10319
0.99
0.12
3.9
4.1
—
—
—
0
0
226
2197
1.02
0.12
3.7
3.9
—
—
—
0
0
18
161
1.11
0.12
1.0
1.1
—
—
—
0
0
186
1896
0.98
0.11
3.2
2.9
3833.8
3653.3
u/ml
0.02
168
1580
18
162
1.11
0.11
1.2
1.8
665.4
4691.9
e6/l
—
10
111
1091
10767
1.01
0.10
5.8
6.2
—
—
—
0
0
39
366
1.06
0.10
2.9
3.2
75.9
39.1
mg/l
0.46
27
276
74
708
1.04
0.10
1.2
1.2
—
—
—
0
0
13
145
0.89
0.10
1.4
1.7
—
—
—
0
0
13
145
0.89
0.10
1.9
2.0
68.6
56.2
umol/l
—
5
105
15
135
1.11
0.09
1.3
1.8
—
—
—
0
0
10
87
1.14
0.09
1.2
1.0
—
—
—
0
0
52
496
1.04
0.08
3.9
3.5
313.9
320.2
umol/l
0.10
40
392
199
1944
1.02
0.08
2.7
3.5
1.5
1.5
mmol/l
0.01
194
1908
458
4606
0.99
0.08
6.3
6.5
—
—
—
0
0
280
2746
1.02
0.08
3.5
3.6
24.1
24.1
mmol/l
0.01
249
2460
12
107
1.12
0.08
2.8
2.1
—
—
—
0
0
8
76
1.05
0.07
13.1
13.6
4.1
5.2
mmol/l
—
8
76
11
98
1.12
0.07
1.1
1.1
—
—
—
0
0
30
283
1.05
0.07
1.5
1.6
1963.3
1741.6
ml
—
6
86
340
3345
1.01
0.06
2.6
3.1
125.1
125.5
g/l
0.16
325
3274
17
182
0.93
0.06
9.0
3.4
49.5
55.3
%
0.35
17
175
15
160
0.93
0.05
1.3
1.7
—
—
—
0
0
18
169
1.06
0.04
2.0
2.2
—
—
—
0
0
143
1405
1.01
0.04
1.6
1.8
21.5
21.8
s
0.45
123
1276
23
238
0.96
0.03
1.3
1.8
—
69.1
—
0
7
50
508
0.98
0.02
5.7
4.2
—
—
—
0
0
49
497
0.98
0.02
3.7
3.6
57.5
59.8
%
0.24
30
276
13
122
1.06
0.02
1.2
1.2
—
—
—
0
0
674
6716
1.00
0.01
5.4
5.9
104.1
104.2
mmol/l
0.28
632
6549
27
263
1.02
0.00
1.1
1.0
267.4
335.1
ng/l
1.65
19
158
11
109
1.00
0.00
1.0
1.0
0.0
0.2
u/ml
—
5
26
10
103
0.97
0.00
1.1
1.4
28.1
28.9
umol/l
—
10
98
11
111
0.99
0.00
1.3
1.2
—
—
—
0
0
14
135
1.03
0.00
2.4
1.9
22.1
58.3
u/l
1.16
14
127
27
265
1.01
0.00
1.1
1.0
715.4
613.4
ng/l
0.42
18
154
12
119
1.00
0.00
1.9
2.0
-0.3
1.1
mmol/l
0.78
12
105
33
323
1.02
0.00
1.2
1.2
1.6
1.4
nmol/l
0.27
27
285
11
113
0.97
0.00
1.1
1.1
—
552.5
—
0
31
18
175
1.02
0.00
1.6
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
13.7
—
0
8
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
0.99
0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
2.0
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.84
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
0.99
0.00
1.0
1.4
—
—
—
0
0
6
68
0.88
0.00
1.3
1.3
—
—
—
0
0
6
60
0.99
0.00
1.3
1.4
44.3
43.3
umol/l
—
6
60
9
90
0.99
0.00
1.8
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_HL_PRESBY and mortality.

Females

Parameter HR [95% CI] p-value
H8_HL_PRESBY 0.901 [0.83, 0.98] 0.013
Birth year 0.994 [0.99, 1.0] 0.113

During the follow-up period (1.1.1998 — 31.12.2019), 17982 out of 34767 females with H8_HL_PRESBY died.

Males

Parameter HR [95% CI] p-value
H8_HL_PRESBY 0.939 [0.85, 1.03] 0.19
Birth year 0.987 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 12373 out of 23536 males with H8_HL_PRESBY died.

Mortality risk

Mortality risk for people of age

years, who have H8_HL_PRESBY.

N-year risk Females Males
1 0.082% 0.164%
5 0.533% 1.051%
10 1.268% 2.716%
15 2.457% 5.224%
20 4.262% 8.789%

Relationships between endpoints

Index endpoint: H8_HL_PRESBY – Presbycusis

GWS hits: 7

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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