Deep bite

K11_DEEP_BITE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.23
  • Hospital discharge: ICD-10 K07.23
  • Cause of death: ICD-10 K07.23

3 out of 7 registries used, show all original rules.

5085

4. Check minimum number of events

None

5085

5. Include endpoints

None

5085

6. Filter based on genotype QC (FinnGen only)

5085

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 167436 80093 87280
Only index persons 138145 66349 71796
Unadjusted period prevalence (%)
Whole population 2.37 2.29 2.44
Only index persons 2.60 2.44 2.74
Median age at first event (years)
Whole population 10.81 10.85 10.76
Only index persons 11.52 11.55 11.48

-FinnGen-

Key figures

All Female Male
Number of individuals 5085 3229 1856
Unadjusted period prevalence (%) 1.00 1.10 0.82
Median age at first event (years) 28.72 27.97 30.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3723
Matched controls
34608
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
10.5
323.0
994
1158
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
11.2
323.0
754
765
K07.23
ICD-10 Finland
Deep bite
+∞
323.0
3724
*
EB1MA
NOMESCO Finland
Cephalometry with X-ray
14.3
323.0
959
819
SBB10
NOMESCO Finland
Teeth copy
12.8
323.0
1853
2493
SAA03
NOMESCO Finland
Extended examination of mouth
4.1
323.0
2600
12454
SAA04
NOMESCO Finland
Special inverstigation of mouth
9.4
323.0
1035
1361
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
6.6
323.0
1195
2299
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
10.9
323.0
956
1060
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
12.6
323.0
776
707
K07.13
ICD-10 Finland
Retrognaty, mandibular
56.5
323.0
927
202
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
24.6
323.0
518
226
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
12.1
323.0
866
846
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
68.1
323.0
423
65
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
14.0
323.0
692
554
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
11.0
323.0
1070
1220
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
11.4
323.0
1080
1195
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
11.1
323.0
1004
1112
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
8.5
320.7
774
1034
SJB60
NOMESCO Finland
External device grinding and adaptation
10.8
316.9
659
675
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
9.9
309.3
675
755
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
5.8
305.3
1010
2088
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
8.1
301.9
752
1049
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
7.1
300.5
826
1335
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.5
276.9
2315
11094
SXC05
NOMESCO Finland
Other oral or dental procedure
5.8
257.5
837
1656
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
6.2
254.5
776
1415
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.4
241.6
715
1247
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
7.2
233.1
619
926
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
8.9
221.0
509
606
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
6.6
218.5
625
1032
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
27.1
217.8
311
116
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
9.4
217.1
481
535
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
14.3
210.1
376
270
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
5.8
207.0
659
1243
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
170.9
1758
8567
SAA02
NOMESCO Finland
Basic examination of mouth
3.2
166.9
3138
21745
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
4.8
165.6
619
1376
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
5.5
145.6
471
883
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
4.9
140.5
505
1065
K07.60
ICD-10 Finland
Snapping jaw
5.3
139.3
468
915
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
7.2
130.5
340
477
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
17.5
123.5
202
113
WZA90
NOMESCO Finland
Other doctors statement
2.5
122.7
1276
5943
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
10.4
116.0
239
226
EBB10
NOMESCO Finland
Insertion of dental implant
15.6
114.2
195
122
SAA01
NOMESCO Finland
Simple examination of mouth
2.5
113.1
2992
21582
OIKH
NOMESCO Finland
NA
4.2
105.1
438
1057
OIKK
NOMESCO Finland
NA
3.4
100.9
548
1656
SJC00
NOMESCO Finland
Bracket with fixed attachment
29.8
100.4
139
45
K03.00
ICD-10 Finland
Approximal wear
4.8
97.5
353
738
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
5.9
94.2
283
477
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.0
90.5
2020
12797
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
4.3
88.2
354
819
SAALT
NOMESCO Finland
NA
5.5
86.4
274
492
K00.00
ICD-10 Finland
Hypodontia
7.6
86.1
214
277
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.9
85.2
609
2212
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
7.8
79.9
194
242
EBB15
NOMESCO Finland
Insertion of dental implant abutment
19.2
78.8
124
62
Z01.2
ICD-10 Finland
Dental examination
1.9
77.4
1935
12487
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
19.8
75.9
118
57
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
3.5
72.5
373
1067
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
30.2
69.1
95
30
SJA01
NOMESCO Finland
Estimation of need for orthodontic care
17.8
68.3
110
59
SDA02
NOMESCO Finland
Parodonthologic therapy
1.9
66.7
1381
8176
OIKVA
NOMESCO Finland
NA
3.9
66.6
293
733
K05.30
ICD-10 Finland
Periodontitis complex
2.8
66.4
485
1765
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.9
65.7
1365
8079
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
63.3
1183
6712
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
26.4
62.6
89
32
-1
NOMESCO Finland
NA
1.8
62.1
1755
11465
OIKAL
NOMESCO Finland
NA
5.5
61.7
192
336
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
60.9
2240
15885
EBA00
NOMESCO Finland
Extraction of tooth
1.8
58.7
1406
8646
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
70.5
57.3
67
9
EMAK
NOMESCO Finland
NA
4.1
57.1
238
566
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
8.1
55.6
131
156
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
8.4
55.6
127
144
WX110
NOMESCO Finland
Local anesthesy
1.8
53.8
2692
20572
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.7
52.5
2024
14247
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.7
51.4
1721
11593
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
15.9
50.3
84
50
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
36.2
49.6
65
17
EB1WA
NOMESCO Finland
NA
14.3
49.3
86
57
K03.64
ICD-10 Finland
Dental calculus supragingival
1.7
48.2
1277
7976
SPB10
NOMESCO Finland
Production of temporary crone to tooth
12.7
47.4
87
65
SJB30
NOMESCO Finland
Extraoral device arrangement and user information
5.9
46.9
137
222
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
6.7
46.4
123
175
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
19.5
46.4
72
35
OIKJA
NOMESCO Finland
NA
9.9
46.3
96
92
K07.24
ICD-10 Finland
Open bite
4.9
44.6
152
295
EEC05
NOMESCO Finland
Le Fort I osteotomy
13.9
42.6
75
51
K02.1
ICD-10 Finland
Caries of dentine
1.6
42.5
2271
17002
SPA02
NOMESCO Finland
Preparation for dental prosthetics
5.8
42.4
125
205
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
6.3
42.1
117
178
OIKRE
NOMESCO Finland
NA
7.0
41.9
108
148
D19
ICPC
Teeth/gum symptom/complaint
1.7
41.1
1095
6775
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.7
41.0
1267
8178
K03.66
ICD-10 Finland
Tooth plaque
2.4
40.6
375
1538
K07.61
ICD-10 Finland
Cracking jaw joint
4.6
40.1
145
300
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.7
39.5
949
5679
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
39.3
1404
9396
K07.10
ICD-10 Finland
Asymmetry of jaw
11.5
38.6
74
61
SJA02
NOMESCO Finland
Plan for orthodontic care
19.9
38.4
59
28
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.8
38.1
781
4437
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
7.5
38.1
93
118
D82
ICPC
Teeth/gum disease
1.6
38.1
1392
9354
SPB20
NOMESCO Finland
Temporary bridge between two or more teeth
15.7
37.7
63
38
SXC03
NOMESCO Finland
Other oral or dental procedure
7.4
37.6
93
120
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
20.7
37.6
57
26
SFA00
NOMESCO Finland
Small filling
2.0
36.8
503
2462
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.8
36.6
818
4771
K07.14
ICD-10 Finland
Retrognaty, maxillary
8.1
36.5
85
100
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
3.2
36.5
201
600
G47.3
ICD-10 Finland
Sleep apnoea
1.9
36.0
630
3384
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
4.9
36.0
124
244
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.2
35.4
400
1804
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
8.6
34.9
78
86
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
8.0
34.7
81
96
K05.31
ICD-10 Finland
Periodontitis pronounced
2.4
34.2
308
1242
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
2.1
34.0
413
1920
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
13.5
33.8
60
42
EBA10
NOMESCO Finland
Surgical removal of tooth
1.9
33.4
597
3222
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.8
33.3
634
3493
SPC01
NOMESCO Finland
Fixed dental crown
7.4
33.2
81
103
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
7.7
32.0
76
93
F45.8
ICD-10 Finland
Other somatoform disorders
2.2
31.2
327
1423
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
31.0
2067
15714
SPC25
NOMESCO Finland
Other demanding attachment of crone of tooth
22.3
30.5
45
19
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
29.5
1255
8606
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.7
29.5
763
4605
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
18.0
29.2
46
24
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
10.1
28.7
58
54
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
2.1
28.5
349
1624
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.7
28.3
638
3697
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
14.6
28.1
48
31
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
13.2
27.5
49
35
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.8
25.6
539
3048
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.6
25.4
849
5456
SJC20
NOMESCO Finland
Extraoral ofthodontisk pulling device arrangement and urser information
6.2
25.4
70
107
R06.5
ICD-10 Finland
Mouth breathing
2.1
24.9
312
1466
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.2
24.7
135
402
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
4.4
24.4
90
192
K02.0
ICD-10 Finland
Caries limited to enamel
1.6
24.3
738
4622
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.8
23.5
415
2213
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.6
23.3
659
4044
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
23.2
2444
19767
K03.0
ICD-10 Finland
Excessive attrition of teeth
3.0
23.1
140
449
K07.4
ICD-10 Finland
Malocclusion, unspecified
3.6
22.9
106
278
SJE90
NOMESCO Finland
Finishing face of orthodontick therapy
5.3
21.9
68
121
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
7.1
21.7
54
72
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
5.4
21.5
66
116
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
2.6
21.5
165
611
SJC04
NOMESCO Finland
NA
11.0
21.4
41
35
K07.33
ICD-10 Finland
Crowding of tooth or teeth
7.9
21.3
49
58
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
20.9
2020
15920
K03.09
ICD-10 Finland
Abrasion of the teeth UNS
5.4
20.8
63
109
OIKKK
NOMESCO Finland
NA
10.4
20.8
41
37
KMAK
NOMESCO Finland
NA
1.4
20.1
1571
11902
VALMI
NOMESCO Finland
NA
1.4
20.0
1193
8600
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.8
19.5
339
1795
ECA50
NOMESCO Finland
Parodontal operation
7.0
19.4
48
64
SPE02
NOMESCO Finland
Metal-framed partial denture
5.6
19.0
56
94
SPA47
NOMESCO Finland
Precision impression for denture
4.5
18.9
68
143
SPE00
NOMESCO Finland
Fitting and preparation of metal structure partial teeth prosthesis
4.5
18.7
68
144
SPAT1386
SPAT
Extensive health check-up on eighth grade
1.7
18.5
382
2134
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
5.5
18.4
55
94
SPF40
NOMESCO Finland
Removal and reattachment with cement of tooth crone or short bridge
4.0
18.2
74
175
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
4.5
18.2
65
136
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
3.7
18.1
80
203
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
8.3
18.0
40
45
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.6
17.5
566
3569
SFC00
NOMESCO Finland
Pillar of fillings material
3.2
17.5
95
284
SPE05
NOMESCO Finland
Demanding fitting and preparation of metal structure partial teeth prosthesis
9.9
17.5
35
33
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
3.4
17.3
84
231
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
7.0
17.0
42
56
K01.0
ICD-10 Finland
Embedded teeth
2.7
16.9
121
432
K08.3
ICD-10 Finland
Retained dental root
2.1
16.8
187
834
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.2
16.5
175
764
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.7
16.5
376
2161
OIKPU
NOMESCO Finland
NA
8.1
16.4
37
43
OIKON
NOMESCO Finland
NA
11.7
16.3
30
24
SBA00
NOMESCO Finland
Microbiological examinations
2.9
16.3
103
340
M79.1
ICD-10 Finland
Myalgia
1.6
16.2
408
2411
K03.08
ICD-10 Finland
Other wear and tear of the teeth
3.1
16.1
92
284
K05.3
ICD-10 Finland
Chronic periodontitis
2.4
16.1
141
563
SPE90
NOMESCO Finland
Other fitting and preparation of partial tooth prosthesis
3.5
15.9
74
197
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
7.8
15.8
36
43
OIKAK
NOMESCO Finland
NA
10.8
15.7
30
26
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
5.5
15.6
46
78
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.3
15.6
80
230
SFC92
NOMESCO Finland
Other demanding adjuvant procedure of filling therapy
2.1
15.4
183
840
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.4
15.3
46
80
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
17.3
15.3
24
13
SDA05
NOMESCO Finland
Very demanding and lengthy parodonthologic therapy
2.1
14.8
166
744
WX290
NOMESCO Finland
Other blockade of nerve
1.3
14.7
1659
13087
Z13.88
ICD-10 Finland
Special screening examination for other specified diseases and disorders
2.0
14.6
180
840
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.4
14.6
1075
7946
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
5.7
14.4
41
67
K07.32
ICD-10 Finland
Displacement of tooth or teeth
7.7
14.4
33
40
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
9.1
14.4
30
31
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
4.2
14.4
54
120
OIKSI
NOMESCO Finland
NA
11.0
14.3
27
23
A98
ICPC
Health maint/preventive medicine
2.1
14.0
3631
32819
OIKTA
NOMESCO Finland
NA
9.7
14.0
28
27
SPA40
NOMESCO Finland
Precision impression for dental prosthesis
7.7
13.9
32
39
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.1
13.7
153
685
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.5
13.7
65
177
SPC08
NOMESCO Finland
Implant crown
10.6
13.6
26
23
A31
ICPC
General and Unspecified, Medical examin/health eval partial
2.2
13.3
136
588
SPA05
NOMESCO Finland
Guiding rail
16.3
13.2
21
12
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.7
13.0
271
1520
SPC30
NOMESCO Finland
Tooth bridge attacment with resins
5.6
12.8
37
62
SFB30
NOMESCO Finland
Filling of tree or more surfaces of tooth reproduced outside mouth
7.4
12.8
30
38
SPA61
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 4 to 6 units
8.2
12.7
28
32
SPE01
NOMESCO Finland
Mucosa-supported partial denture
4.0
12.7
51
121
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.7
12.5
269
1520
K06.20
ICD-10 Finland
Gingival hyperplasia caused by traumatic bait
17.7
12.4
19
10
SPA50
NOMESCO Finland
Determination of bite and dental arch location
4.7
12.4
41
81
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
12.1
12.3
22
17
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
6.6
12.3
31
44
ECA55
NOMESCO Finland
Complicated parodontal operation
5.8
12.2
34
55
K06.18
ICD-10 Finland
Another gingival hyperplasia
6.8
12.2
30
41
P01AB01
ATC
metronidazole; oral, rectal
1.3
12.1
1075
8125
ECA30
NOMESCO Finland
Excision of lesion of gingiva
3.7
12.1
53
136
SPC09
NOMESCO Finland
Implant crown, demanding
29.9
12.1
16
5
K06.00
ICD-10 Finland
Local gingivore traction
3.1
12.0
65
197
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
12.3
11.8
21
16
SPAT1316
SPAT
Extensive health check-up of children and adolescents
1.4
11.7
788
5703
N03AX16
ATC
pregabalin; oral
1.4
11.4
561
3844
SPC05
NOMESCO Finland
Fixed dental crown, demanding
12.4
11.4
20
15
G50.1
ICD-10 Finland
Atypical facial pain
3.1
11.4
60
179
J01CA04
ATC
amoxicillin; systemic
1.3
11.2
3010
26254
HAMTE
NOMESCO Finland
NA
5.0
11.2
35
65
SPA01
NOMESCO Finland
Pre-prosthetic dental procedures
9.0
11.1
23
24
SPF11
NOMESCO Finland
Fitting of dental prosthesis
6.0
11.1
30
47
ECB05
NOMESCO Finland
Mucogingival repair
5.7
11.0
31
51
SHC02
NOMESCO Finland
Raising the bite
32.6
10.9
14
*
POLI
NOMESCO Finland
NA
32.6
10.9
14
*
K03.29
ICD-10 Finland
Erosion of teeth occupational
3.5
10.8
49
131
J01FA10
ATC
azithromycin; systemic
1.3
10.7
2209
18537
K04.1
ICD-10 Finland
Necrosis of pulp
1.6
10.6
298
1809
OIKIN
NOMESCO Finland
NA
4.4
10.6
37
78
SPB30
NOMESCO Finland
Temporary partial teeth prothesis
8.6
10.4
22
24
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.7
10.4
226
1281
N06AX21
ATC
duloxetine; oral
1.6
10.3
292
1778
SBA10
NOMESCO Finland
Measurement of excretion of saliva
4.1
10.3
39
89
R5140
NOMESCO Finland
Monitoring the use of the aid
1.6
10.3
246
1432
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
20.0
10.3
15
7
L15
ICPC
Knee symptom/complaint
1.4
10.2
667
4793
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
10.2
557
3887
HAHOM
NOMESCO Finland
NA
2.8
10.2
63
208
ECB20
NOMESCO Finland
Oral alveoplasty
4.9
10.1
32
61
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
3.8
10.1
41
100
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
13.2
10.0
17
12
ECA20
NOMESCO Finland
Biopsy of gingiva
3.9
9.9
39
93
OIKNV
NOMESCO Finland
NA
7.6
9.7
22
27
K04.7
ICD-10 Finland
Periapical abscess without sinus
1.8
9.7
153
786
OIKKE
NOMESCO Finland
NA
5.3
9.6
28
49
EDC30
NOMESCO Finland
Genioplasty
13.6
9.6
16
11
M01AE02
ATC
naproxen; oral, rectal
1.2
9.5
1960
16331
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
9.5
1803
14884
EBA40
NOMESCO Finland
Excision of apex of root of tooth
3.3
9.5
47
135
SPA45
NOMESCO Finland
Precision impression for dental prosthesis, demanding
9.3
9.5
19
19
A02BC05
ATC
esomeprazole; systemic
1.3
9.5
999
7683
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.7
9.3
39
98
N06AB04
ATC
citalopram; systemic
1.4
9.3
513
3584
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
3.0
9.3
53
167
SPF41
NOMESCO Finland
Repair of dental crown, bridge or implant structure, standard
3.7
9.1
39
100
K03.28
ICD-10 Finland
Other erosion of teeth
2.7
9.1
59
203
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
9.0
142
732
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
16.3
9.0
14
8
N06AX11
ATC
mirtazapine; oral
1.3
9.0
828
6251
SGA03
NOMESCO Finland
Demanding opening and dilatation of root canal of tooth
1.5
8.9
267
1649
SDC10
NOMESCO Finland
Parodontological fixation
4.1
8.9
33
75
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.3
8.8
643
4693
K08.80
ICD-10 Finland
Toothache NOS
1.6
8.8
243
1470
K05.11
ICD-10 Finland
Gingivitis (chronic) hyperplastic
5.7
8.8
24
39
SPF42
NOMESCO Finland
Repair of dental crown, bridge or implant structure, demanding
12.7
8.8
15
11
K03.2
ICD-10 Finland
Erosion of teeth
2.5
8.7
66
246
SPB11
NOMESCO Finland
Production and temporary attachment of temporary clinic-made tooth- or implant-retained structure, 1 to 3 units
22.4
8.6
12
5
EEC02
NOMESCO Finland
Rapid expansion of maxilla
17.3
8.6
13
7
SPF10
NOMESCO Finland
Demanding repatation of teeth prosthesis
3.1
8.6
45
136
SGA04
NOMESCO Finland
Very demanding opening and dilatation of root canal of tooth
1.5
8.5
317
2052
E0000UV
ATC
NA
1.2
8.4
1265
10128
N01
ICPC
Headache
1.3
8.4
644
4734
SFB40
NOMESCO Finland
Filling of four surfaces reproduced outside mouth
4.7
8.3
27
54
K05.18
ICD-10 Finland
Chronic gingivitis
1.7
8.3
162
894
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
8.2
570
4127
SPC50
NOMESCO Finland
Pivot column
25.6
8.2
11
*
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
4.8
8.1
26
51
EB1KA
NOMESCO Finland
Partial (restricted area) panoramic tomography of teeth or jaw
6.1
8.1
21
32
S82
ICPC
Naevus/mole
1.4
8.1
357
2395
ZXA10
NOMESCO Finland
Bilateral
1.4
8.1
481
3398
AA40B
NOMESCO Finland
NA
5.7
8.1
22
36
R51.80
ICD-10 Finland
Headache
1.4
8.0
490
3477
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
11.9
8.0
14
11
K03.1
ICD-10 Finland
Abrasion of teeth
2.3
8.0
69
280
R01AD09
ATC
mometasone; nasal
1.2
7.9
1374
11157
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
7.9
755
5717
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.5
7.9
309
2026
N06AB10
ATC
escitalopram; oral
1.3
7.8
640
4742
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
7.8
900
6976
K07.28
ICD-10 Finland
Another anomaly in the relationship between the dental arches
6.6
7.8
19
27
EG1CG
NOMESCO Finland
Extensive MRI examination of mandipular joint with high intensity magnet
4.5
7.8
26
54
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
4.9
7.7
24
46
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
7.7
761
5782
SPF30
NOMESCO Finland
Soling for prothesis
3.0
7.7
42
131
R51.81
ICD-10 Finland
Facial pain NOS
2.3
7.7
67
273
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.0
7.7
95
450
SPF50
NOMESCO Finland
Removal and reattachment with cement of tooth bridnge
5.6
7.6
21
35
K07.68
ICD-10 Finland
Other disorders of the jaw joint
3.3
7.5
35
98
D01
ICPC
Abdominal pain/cramps general
1.4
7.4
436
3073
SPF20
NOMESCO Finland
Temporary soling for filling
4.1
7.4
27
61
SPAT1363
SPAT
Health check-up performed during first study year in students of upper secondary schools, vocational schools etc.
1.3
7.4
850
6579
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
7.3
1088
8667
SCB01
NOMESCO Finland
Simple training for mouth care at home
2.2
7.3
69
291
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
7.3
1013
8010
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
6.9
7.2
17
23
ECW05
NOMESCO Finland
Restricted insertion of mini-implant or miniscrew
74.6
7.2
8
*
EDC05
NOMESCO Finland
Segmental osteotomy of mandible
74.6
7.2
8
*
T84.60
ICD-10 Finland
Gingivitis associated with dental implants
5.2
7.2
21
38
SAAPA
NOMESCO Finland
NA
3.1
7.1
36
107
G47.8
ICD-10 Finland
Other sleep disorders
3.2
7.1
35
103
K07.6
ICD-10 Finland
Temporomandibular joint disorders
3.4
7.1
32
88
ECA70
NOMESCO Finland
Regenerative parodontal operation or gingiva and alveolus transplantation
5.0
7.0
21
39
SCF02
NOMESCO Finland
Preventive oral care by dental hygienist
1.5
7.0
217
1351
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
6.9
262
1704
L12
ICPC
Hand/finger symptom/complaint
1.3
6.9
500
3640
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
2.9
6.9
40
130
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.5
6.9
49
181
K02.2
ICD-10 Finland
Caries of cementum
1.9
6.8
89
433
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
6.8
189
1150
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.7
640
4835
N06AA09
ATC
amitriptyline; systemic
1.5
6.7
202
1254
S29
ICPC
Skin symptom/complaint other
1.3
6.7
485
3532
SPC35
NOMESCO Finland
Production and attachment of single tooth bridge
2.9
6.7
39
128
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
6.6
1667
13970
EOVET
NOMESCO Finland
NA
12.8
6.6
11
8
XA420
NOMESCO Finland
Extensive sleep examination
2.9
6.6
38
123
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
6.6
182
1105
SPAT1324
SPAT
Screening procedure
1.3
6.5
463
3356
J01FF01
ATC
clindamycin; systemic
1.3
6.5
653
4960
K00.9
ICD-10 Finland
Disorder of tooth development, unspecified
37.2
6.5
8
*
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
3.4
6.5
29
79
Z46.3
ICD-10 Finland
Fitting and adjustment of dental prosthetic device
2.8
6.5
39
131
N03AX12
ATC
gabapentin; oral
1.4
6.5
341
2361
L03
ICPC
Low back symptom/complaint
1.3
6.5
697
5346
SPA48
NOMESCO Finland
Precision impression for denture, demanding
6.2
6.4
16
24
SPAT1058
SPAT
PEF monitoring instruction
1.5
6.4
216
1375
L01
ICPC
Neck symptom/complaint
1.3
6.3
406
2902
N05AH04
ATC
quetiapine; oral
1.3
6.3
503
3712
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
6.3
435
3144
N06AB05
ATC
paroxetine; oral
1.6
6.2
149
876
K03.24
ICD-10 Finland
Erosion of teeth NOS
8.1
6.2
13
15
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
6.2
652
4983
ZXC60
NOMESCO Finland
Application of heat
2.4
6.2
48
187
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.5
6.1
214
1372
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.7
6.1
123
687
K08.0
ICD-10 Finland
Exfoliation of teeth due to systemic causes
13.3
6.1
10
7
R53
ICD-10 Finland
Malaise and fatigue
1.3
6.1
523
3895
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
1.7
6.1
123
688
R52.2
ICD-10 Finland
Other chronic pain
1.9
6.1
85
424
K05.20
ICD-10 Finland
Periodontal abscess without fistula
2.9
6.1
35
113
N06AX16
ATC
venlafaxine; oral
1.3
6.1
388
2771
SPE10
NOMESCO Finland
Fitting and preparation of partial tooth prosthesis attached with implants
+∞
6.1
6
*
ECU05
NOMESCO Finland
Restricted removal of mini-implant or miniscrew
+∞
6.1
6
*
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.3
6.1
651
4989
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
4.4
6.1
20
42
KIP00
NOMESCO Finland
NA
6.9
6.0
14
19
TEG00
NOMESCO Finland
Punction of mandibular joint
6.9
6.0
14
19
R03AC02
ATC
salbutamol; inhalant
1.2
6.0
1637
13767
K03.30
ICD-10 Finland
Internal granuloma of pulp
4.7
6.0
19
38
OIKAP
NOMESCO Finland
NA
5.3
6.0
17
30
Z00.1
ICD-10 Finland
Routine child health examination
1.3
6.0
502
3726
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
3.6
6.0
25
65
K07.2
ICD-10 Finland
Anomalies of dental arch relationship
16.8
6.0
9
5
ECW06
NOMESCO Finland
Insertion of mini-implant or miniscrew
16.8
6.0
9
5

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3073
24268
1.29
15.55
4.6
3.9
9.0
9.8
mm/h
4.40
2858
22566
1259
9051
1.29
12.74
1.5
1.5
2.0
2.0
g/l
1.58
750
5394
801
5418
1.35
12.48
2.8
2.8
106.2
120.7
ug/g
0.82
655
4297
37
86
3.78
11.92
7.7
8.0
3.0
2.5
mg/l
0.57
29
71
1405
10325
1.27
11.74
1.5
1.5
1.5
2.0
u/ml
1.30
326
2545
1931
14795
1.23
10.95
8.7
7.0
1.2
1.2
mmol/l
1.03
1671
12781
3362
27348
1.24
10.58
4.1
3.8
14.5
14.5
pmol/l
0.02
3011
24888
2214
17255
1.22
10.51
7.2
6.3
54.3
54.9
%
1.53
2097
16262
2241
17515
1.22
10.25
7.4
6.5
31.2
30.6
%
2.11
2125
16462
2157
16869
1.21
9.55
7.7
6.8
8.3
8.3
%
0.11
2040
15890
2115
16560
1.21
9.10
3.2
2.8
74.5
89.5
ug/l
3.89
1985
15555
2137
16760
1.21
9.00
7.5
6.5
2.9
2.9
%
0.40
2025
15724
2329
18416
1.20
8.98
7.4
6.4
2.0
2.0
e9/l
1.53
2093
16338
2332
18446
1.20
8.94
7.8
6.7
0.2
0.2
e9/l
0.19
2091
16297
2255
17836
1.20
8.48
7.5
6.4
0.0
0.0
e9/l
0.08
1991
15477
229
1322
1.54
8.44
17.0
9.9
1.3
1.2
mg/l
0.52
217
1269
2249
17789
1.20
8.44
7.5
6.4
0.6
0.6
e9/l
0.26
1992
15440
330
2063
1.43
8.19
8.9
5.3
—
—
—
0
0
2059
16213
1.19
7.96
7.7
6.6
0.7
0.7
%
0.72
1946
15222
3793
31570
1.23
7.92
4.8
4.5
1.8
2.0
mu/l
1.35
3530
29502
1568
12081
1.20
7.63
7.5
6.6
—
—
—
0
0
113
562
1.78
7.48
4.4
3.4
—
—
—
0
0
314
1981
1.41
7.43
8.2
5.3
24.4
24.4
mmol/l
0.14
306
1920
1583
12236
1.19
7.38
5.8
5.3
37.4
36.7
g/l
5.95
1468
11485
395
2611
1.35
7.05
8.4
5.1
7.4
7.4
ph
1.07
34
231
450
3033
1.33
7.04
9.2
5.1
4.8
4.8
kpa
0.38
439
2938
1733
13551
1.18
6.99
3.0
2.4
74.2
72.7
nmol/l
1.48
1595
12533
1727
13509
1.18
6.91
8.6
6.6
1.2
1.2
mmol/l
1.14
1577
12432
204
1203
1.50
6.88
6.2
4.5
0.3
0.3
g/l
0.23
112
630
509
3503
1.30
6.86
9.3
5.4
7.3
7.4
ph
—
8
17
55
220
2.20
6.79
44.8
39.4
6.7
7.1
ug/l
1.06
48
201
395
2627
1.34
6.77
8.4
5.1
5.1
5.1
kpa
0.20
373
2493
256
1591
1.43
6.61
11.0
5.6
9.8
9.5
kpa
2.03
241
1516
236
1445
1.45
6.60
1.6
1.8
—
—
—
0
0
4146
35026
1.24
6.32
12.2
11.4
20.3
21.8
mg/l
2.07
3013
26241
498
3457
1.29
6.29
9.3
5.4
5.9
5.9
kpa
0.24
487
3346
146
817
1.58
6.26
1.3
1.4
302.1
306.6
ug/g
0.10
78
429
495
3438
1.29
6.22
9.3
5.4
1.5
1.7
mmol/l
0.70
428
2767
2494
20207
1.16
6.19
9.4
9.0
3.8
3.9
e9/l
2.27
2200
17596
421
2865
1.31
6.17
1.3
1.3
194.4
277.2
u/ml
2.02
400
2641
589
4192
1.26
6.07
1.6
1.7
1080.8
1156.1
nmol/l
1.34
451
3250
324
2136
1.35
5.91
1.4
1.4
—
—
—
0
0
215
1326
1.44
5.83
1.3
1.2
0.8
1.0
u/ml
0.12
12
110
461
3206
1.28
5.74
4.7
3.7
1.5
1.7
%
3.70
421
2921
642
4646
1.24
5.71
3.1
2.4
14.8
14.0
umol/l
1.74
595
4345
539
3831
1.26
5.62
1.2
1.2
—
—
—
0
0
1396
10879
1.17
5.59
1.9
1.8
97.1
97.2
pmol/l
0.02
706
5834
268
1732
1.37
5.57
1.9
1.7
7.5
8.2
u/l
0.51
211
1334
341
2288
1.33
5.54
3.3
3.1
63.4
70.3
e9/l
3.09
250
1675
1326
10300
1.17
5.51
7.9
7.1
1.2
1.2
inr
0.04
370
3267
581
4198
1.24
5.24
3.1
2.4
2.5
2.5
g/l
1.77
536
3921
4016
33956
1.20
5.21
13.7
12.3
39.9
40.1
%
0.77
3109
27168
489
3477
1.26
5.09
2.6
2.2
352.2
370.7
nmol/l
1.05
458
3241
210
1324
1.40
5.08
2.5
2.3
—
—
—
0
0
363
2491
1.30
5.03
2.3
2.2
12.3
11.4
nmol/l
0.99
310
2196
511
3658
1.25
5.01
1.5
1.5
—
—
—
0
0
348
2384
1.30
4.89
10.2
5.9
23.9
24.0
mmol/l
0.40
336
2266
655
4834
1.21
4.81
1.4
1.4
545.5
544.5
titre
0.00
127
937
81
420
1.70
4.78
3.5
2.8
7.1
7.2
mmol/l
0.10
81
408
823
6212
1.19
4.74
1.6
1.6
—
—
—
0
0
41
171
2.11
4.68
2.7
1.8
—
—
—
0
0
354
2447
1.29
4.66
4.5
4.5
1.0
0.4
%
0.29
89
565
603
4429
1.22
4.64
3.2
2.8
29.6
29.8
s
0.33
585
4304
318
2175
1.30
4.55
1.2
1.2
—
—
—
0
0
394
2769
1.27
4.54
13.3
8.9
7.3
7.4
mmol/l
0.18
384
2671
1201
9379
1.16
4.53
2.5
2.6
59.6
56.4
u/l
0.88
1103
8683
87
467
1.64
4.53
4.0
2.7
1.4
1.5
mmol/l
1.05
87
449
51
234
1.92
4.50
2.4
2.4
—
—
—
0
0
534
3887
1.23
4.50
3.3
2.5
24.4
23.2
%
1.04
455
3406
403
2852
1.26
4.39
3.0
3.0
9.8
10.3
g/l
1.94
372
2637
35
143
2.15
4.23
2.2
1.7
—
—
—
0
0
960
7417
1.16
4.14
3.8
3.2
—
—
—
0
0
1235
9739
1.15
4.01
3.2
3.1
2.4
2.4
mmol/l
0.09
1076
8729
420
3019
1.24
4.00
1.2
1.2
113.1
147.9
iu/ml
1.42
153
1098
596
4437
1.20
3.99
10.5
6.9
1.1
1.1
mmol/l
1.42
549
4170
73
390
1.65
3.92
3.6
2.7
10.8
10.2
%
0.17
48
260
791
6044
1.17
3.92
1.6
1.5
20.6
20.2
nmol/l
0.36
678
5319
2842
23625
1.13
3.90
6.9
6.9
83.4
81.5
u/l
1.07
2686
22300
352
2490
1.25
3.87
4.2
4.1
0.5
0.6
%
0.09
83
525
366
2604
1.25
3.83
1.6
1.4
—
—
—
0
0
362
2574
1.25
3.81
4.5
4.4
0.1
0.1
%
0.19
104
659
94
538
1.54
3.81
2.9
3.1
19.6
25.5
mu/l
1.16
89
496
151
950
1.40
3.79
4.6
6.0
0.9
0.9
%
0.37
145
882
152
961
1.40
3.72
4.7
5.9
1.5
1.7
%
1.42
144
891
377
2701
1.24
3.72
4.5
4.4
0.9
0.8
%
0.25
105
716
190
1246
1.35
3.71
1.1
1.1
11.3
4.9
u/ml
0.42
26
156
21
417
0.44
3.68
3.0
3.7
14.5
29.7
u/ml
2.89
21
406
50
245
1.79
3.67
4.7
3.0
144.4
263.0
e6/l
3.54
39
159
242
1649
1.30
3.62
7.3
4.1
129.8
130.8
g/l
0.31
237
1603
150
953
1.39
3.58
1.1
1.1
6.6
5.4
u/ml
0.17
72
456
1039
8156
1.15
3.56
2.6
2.4
2.7
2.8
mg/l
0.38
904
7054
267
1847
1.28
3.56
3.2
3.0
115.2
146.1
ng/l
1.09
242
1638
692
5278
1.17
3.50
3.6
2.7
1.1
1.0
e6/l
0.22
414
2905
196
1305
1.33
3.48
4.4
2.8
—
—
—
0
0
1340
10732
1.13
3.34
3.8
3.4
29.5
33.2
u/l
1.50
1279
10237
42
202
1.83
3.30
3.4
3.2
2.8
2.8
mmol/l
0.07
37
188
215
1462
1.30
3.30
1.2
1.2
3.5
2.6
u/ml
0.33
109
761
1211
9647
1.13
3.29
3.2
3.0
22.4
40.1
ng/l
2.24
681
5380
29
123
2.07
3.26
1.9
1.8
—
—
—
0
0
68
376
1.59
3.25
3.0
3.9
—
—
—
0
0
99
595
1.46
3.24
2.3
1.6
—
—
—
0
0
309
2205
1.24
3.20
6.8
4.6
71.2
73.8
ng/l
0.33
274
2003
524
3938
1.18
3.18
1.2
1.2
—
—
—
0
0
2188
18048
1.11
3.18
5.1
4.8
6.2
6.4
mmol/l
7.04
2010
16743
430
3184
1.20
3.09
11.1
9.2
—
—
—
0
0
129
823
1.38
3.06
4.6
6.7
1.2
1.2
mmol/l
0.07
115
720
135
870
1.37
3.01
1.1
1.1
12.7
8.3
u/ml
0.52
65
445
185
1251
1.31
2.99
1.1
1.1
2.5
3.5
u/ml
0.39
58
381
109
679
1.41
2.97
1.9
1.8
193.7
187.6
pmol/l
0.22
104
646
436
3247
1.19
2.95
1.4
1.4
—
—
—
0
0
2685
22435
1.10
2.94
4.9
3.9
—
—
—
0
0
177
1196
1.31
2.89
1.1
1.2
—
—
—
0
0
71
409
1.53
2.88
3.4
2.9
38.7
42.7
%
—
6
38
78
459
1.49
2.87
3.9
2.9
1.2
1.3
e9/l
0.03
60
296
4250
36454
1.15
2.82
11.5
10.2
—
—
—
0
0
1782
14612
1.11
2.81
3.9
3.9
—
—
—
0
0
152
1011
1.33
2.78
2.0
1.6
—
—
—
0
0
3955
33775
1.13
2.75
13.7
12.3
139.8
139.6
mmol/l
3.02
3847
32820
145
961
1.33
2.73
2.1
1.7
113.4
108.8
u/ml
0.20
25
143
306
2222
1.22
2.72
1.8
1.6
21.6
21.1
iu/l
0.08
248
1780
192
1323
1.28
2.72
1.1
1.1
7.3
7.4
u/ml
0.02
115
835
3382
30486
0.90
2.70
4.5
4.1
2.8
2.8
mmol/l
1.03
3142
28484
169
1147
1.30
2.69
1.7
1.8
0.2
0.2
g/l
0.58
156
1095
21
85
2.17
2.69
1.3
1.2
18.6
21.2
u/ml
—
5
19
1007
8028
1.12
2.66
2.2
2.2
168.6
220.5
u/l
1.60
944
7629
101
637
1.40
2.61
1.3
1.4
17.7
19.9
u/l
0.37
75
548
102
1218
0.73
2.61
1.5
1.4
—
—
—
0
0
151
1014
1.31
2.61
2.0
1.6
33.9
22.8
u/ml
—
5
21
3960
33857
1.12
2.55
13.8
12.4
3.9
3.9
mmol/l
0.22
3844
32812
3598
30603
1.11
2.54
15.7
13.9
13.3
13.4
%
1.22
3519
29914
280
2031
1.22
2.54
1.1
1.1
52.3
2.8
u/ml
—
7
24
172
1181
1.28
2.53
1.7
1.7
1.2
1.2
g/l
0.09
162
1129
181
1252
1.27
2.51
1.9
1.5
235.4
217.9
u/ml
0.30
87
685
47
255
1.62
2.50
9.0
10.9
0.7
0.6
mmol/l
0.31
42
236
39
202
1.69
2.47
1.1
1.0
9.7
6.5
u/ml
—
5
20
4596
39727
1.21
2.45
18.3
16.6
6.5
6.7
e9/l
3.28
4459
38456
143
963
1.31
2.44
1.4
1.5
59.1
85.6
titre
1.18
11
93
110
715
1.35
2.40
3.8
3.8
53.0
55.1
%
1.02
110
715
34
171
1.74
2.39
1.2
1.2
—
—
—
0
0
157
1741
0.78
2.39
1.4
1.4
—
—
—
0
0
23
102
1.98
2.37
2.8
2.8
—
—
—
0
0
4592
39700
1.20
2.36
18.2
16.5
89.2
89.4
fl
3.14
4527
39138
4589
39672
1.20
2.36
18.3
16.6
260.4
260.2
e9/l
0.05
4455
38503
4593
39710
1.20
2.36
18.2
16.5
4.6
4.6
e12/l
0.45
4452
38436
4592
39703
1.20
2.34
18.2
16.5
29.8
29.9
pg
0.83
4527
39142
201
1423
1.25
2.32
3.7
2.7
0.2
0.3
e6/l
0.12
193
1384
5
7
6.25
2.32
10.2
4.3
—
—
—
0
0
40
213
1.65
2.31
2.1
2.3
117.9
140.7
ng/l
0.54
34
180
276
2021
1.21
2.30
1.2
1.2
—
—
—
0
0
48
269
1.57
2.27
2.3
1.8
22.9
22.6
umol/l
0.02
48
257
4594
39733
1.20
2.25
18.3
16.6
135.9
135.9
g/l
0.05
4529
39177
301
2231
1.19
2.21
2.1
1.8
1.4
1.3
g/l
0.47
282
2078
498
3845
1.15
2.19
1.6
1.7
—
—
—
0
0
19
81
2.06
2.18
4.4
2.8
18.9
36.1
mg/l
—
9
30
86
547
1.38
2.17
5.4
8.4
11.0
11.5
mmol/l
0.72
80
488
3369
30265
0.91
2.17
4.2
3.8
4.6
4.7
mmol/l
1.45
3148
28494
86
548
1.38
2.15
5.4
8.4
105.5
105.6
mmol/l
0.05
80
489
181
1279
1.25
2.15
1.1
1.1
1.4
1.3
u/ml
0.02
98
713
1026
8286
1.11
2.12
4.9
3.8
7.4
7.4
ph
0.37
177
1555
345
2601
1.17
2.09
1.2
1.2
52.5
250.6
titre
1.70
12
77
1448
11895
1.09
2.08
1.9
1.9
—
—
—
0
0
640
5041
1.13
2.08
3.8
2.8
4.2
3.4
e6/l
0.92
360
2670
1134
9214
1.10
2.07
3.7
3.4
8.0
8.2
mmol/l
0.55
981
8067
99
650
1.34
2.07
5.6
3.6
—
—
—
0
0
711
5638
1.12
2.06
1.3
1.3
23.8
28.0
iu/ml
0.56
198
1635
0
51
0.00
2.06
0.0
6.4
—
—
—
0
0
766
6101
1.12
2.06
3.6
2.7
570.7
569.9
mosm/kgh2o
0.03
654
5233
209
2203
0.82
2.05
3.7
4.1
12.7
20.7
ug/l
0.52
161
1712
1114
9051
1.10
2.03
3.5
2.9
—
—
—
0
0
16
275
0.51
2.02
1.1
1.2
—
—
—
0
0
59
356
1.46
2.01
1.0
1.1
—
—
—
0
0
1818
15106
1.08
1.98
5.8
6.1
11.1
11.0
umol/l
0.15
1705
14200
406
3116
1.15
1.96
3.5
3.0
0.2
0.2
g/l
0.96
390
2933
3339
29961
0.92
1.96
4.2
3.7
1.5
1.5
mmol/l
0.29
3101
28064
1934
16115
1.08
1.96
3.8
3.3
0.0
0.0
estimate
0.50
345
3021
693
5506
1.12
1.95
1.6
1.6
61130581.5
34423178.7
pmol/l
0.35
584
4712
1006
8155
1.10
1.92
5.3
4.4
—
—
—
0
0
111
751
1.30
1.90
1.1
1.1
0.4
0.5
u/ml
0.12
30
221
20
92
1.91
1.90
1.3
1.1
—
—
—
0
0
13
51
2.23
1.84
2.5
2.5
—
—
—
0
0
27
139
1.70
1.82
3.4
2.7
—
—
—
0
0
16
69
2.03
1.82
2.8
3.2
—
—
—
0
0
78
506
1.35
1.80
7.4
3.7
—
—
—
0
0
920
7456
1.10
1.77
3.6
3.4
1.0
1.0
kg/l
1.76
131
1078
139
978
1.25
1.77
1.3
1.2
18.6
36.8
u/ml
0.56
13
55
299
2267
1.16
1.73
3.1
3.2
4.7
4.7
pmol/l
0.19
267
2049
462
3613
1.13
1.72
4.9
3.5
6.3
7.1
umol/l
0.39
405
3114
71
458
1.36
1.71
2.5
3.5
1.3
1.4
%
0.03
62
371
20
96
1.83
1.70
3.5
4.2
53.6
48.0
%
0.55
20
90
131
921
1.25
1.69
3.3
3.1
—
—
—
0
0
6
16
3.28
1.69
1.7
1.8
—
—
—
0
0
112
773
1.27
1.69
1.3
1.2
64.5
41.4
u/ml
—
10
62
21
103
1.79
1.67
1.2
1.2
—
—
—
0
0
42
247
1.49
1.67
1.5
1.5
0.9
0.9
g/l
0.26
42
247
380
3746
0.88
1.67
1.3
1.3
—
—
—
0
0
23
333
0.60
1.65
1.4
1.2
—
—
—
0
0
16
72
1.95
1.64
1.2
1.3
38.2
40.2
g/l
—
8
44
951
7747
1.09
1.64
1.6
1.6
1.4
1.4
mmol/l
0.28
820
6698
1926
16133
1.07
1.63
5.3
4.5
0.0
0.0
estimate
0.80
353
3137
27
144
1.64
1.62
4.1
4.5
—
—
—
0
0
88
991
0.77
1.62
1.6
1.5
—
—
—
0
0
1385
11466
1.08
1.61
4.8
3.6
38.0
77.4
e6/l
5.78
944
7812
59
374
1.38
1.60
4.4
3.0
488.2
542.7
e6/l
0.41
49
304
85
959
0.77
1.59
1.5
1.5
—
—
—
0
0
28
152
1.61
1.58
3.3
2.7
—
—
—
0
0
13
55
2.07
1.57
2.0
3.0
—
—
—
0
0
42
252
1.46
1.54
4.8
3.7
—
—
—
0
0
1938
16264
1.07
1.53
3.9
3.3
0.0
0.0
estimate
0.08
346
3040
40
238
1.47
1.53
2.1
1.4
—
—
—
0
0
58
370
1.38
1.53
4.4
3.0
0.2
0.2
e9/l
0.12
49
305
86
963
0.78
1.53
1.5
1.5
—
—
—
0
0
18
87
1.81
1.52
1.1
1.2
—
—
—
0
0
18
87
1.81
1.52
1.1
1.2
—
—
—
0
0
18
87
1.81
1.52
1.1
1.2
—
—
—
0
0
11
44
2.19
1.51
1.4
1.4
—
—
—
0
0
144
1039
1.22
1.50
1.1
1.1
—
—
—
0
0
108
755
1.26
1.50
10.0
4.1
23.4
24.3
mmol/l
2.14
100
687
662
5328
1.10
1.49
1.3
1.3
10.2
10.0
u/ml
0.02
258
2072
298
2289
1.15
1.49
3.4
3.3
—
—
—
0
0
275
2101
1.15
1.48
1.6
1.6
327.3
326.6
mu/l
0.01
253
1897
611
5817
0.91
1.47
1.7
1.8
—
—
—
0
0
299
2301
1.15
1.46
2.0
2.5
3.8
4.1
e9/l
2.18
231
1892
585
4685
1.10
1.46
7.8
5.0
0.8
0.8
mmol/l
0.65
543
4433
34
198
1.51
1.45
1.1
1.1
25.9
9.9
u/ml
—
7
40
151
1100
1.21
1.44
1.3
1.2
—
—
—
0
0
84
574
1.28
1.41
3.8
3.5
2.4
1.6
ratio
0.46
11
51
12
52
2.02
1.38
1.3
1.1
—
—
—
0
0
1912
16083
1.07
1.38
10.2
8.9
0.0
0.0
e9/l
0.19
1580
13066
0
35
0.00
1.34
0.0
1.3
—
1.8
—
0
21
1062
8769
1.08
1.31
4.3
3.1
0.3
0.3
e6/l
0.47
804
6517
67
451
1.30
1.29
1.1
1.4
—
—
—
0
0
58
383
1.33
1.27
1.1
1.1
4.7
8.2
iu/ml
—
10
91
23
127
1.59
1.26
1.1
1.1
—
—
—
0
0
3709
31903
1.07
1.25
15.6
14.1
334.0
333.4
g/l
3.74
3681
31603
106
758
1.23
1.25
1.1
1.1
—
—
—
0
0
57
377
1.33
1.24
1.3
1.3
16.9
31.5
u/l
1.23
51
326
125
910
1.21
1.24
1.3
1.2
3.6
14.2
u/ml
2.76
23
140
171
1282
1.17
1.22
1.1
1.1
—
—
—
0
0
245
1888
1.14
1.21
3.6
2.7
66.8
66.8
g/l
0.03
223
1755
106
761
1.22
1.21
1.1
1.1
—
—
—
0
0
2518
21422
1.06
1.20
4.6
3.9
1504.9
1215.6
e6/l
0.13
36
273
23
129
1.56
1.19
2.4
2.1
—
—
—
0
0
847
6963
1.08
1.19
2.3
2.0
0.9
1.1
mg/l
0.92
608
5061
84
590
1.25
1.18
4.0
3.5
31.9
63.7
mg/l
1.74
69
480
123
900
1.20
1.17
1.3
1.2
3.4
4.7
u/ml
0.34
14
92
144
1069
1.18
1.17
1.9
2.0
1.2
1.4
g/l
2.37
122
932
11
174
0.55
1.16
1.3
1.4
5.8
6.2
mmol/l
0.34
11
159
278
2168
1.13
1.16
6.1
3.7
1.2
1.2
mmol/l
0.57
240
1891
51
336
1.33
1.16
1.1
1.1
194.6
246.7
mg/l
1.67
44
290
72
498
1.27
1.15
7.9
3.3
—
—
—
0
0
84
592
1.25
1.15
4.0
3.5
31.4
40.1
mg/l
0.62
68
483
93
663
1.23
1.15
7.3
4.1
1.8
2.3
mmol/l
1.43
54
407
1055
8757
1.07
1.13
4.1
3.0
—
—
—
0
0
16
83
1.69
1.12
3.2
2.6
—
—
—
0
0
372
2958
1.11
1.11
1.6
2.0
—
—
—
0
0
99
714
1.22
1.10
1.1
1.1
3.3
3.6
u/ml
0.07
54
277
52
347
1.31
1.10
4.9
3.4
—
—
—
0
0
99
715
1.22
1.09
1.5
1.4
5.4
4.9
ug/l
0.15
87
665
916
7577
1.07
1.09
3.6
3.3
—
—
—
0
0
103
748
1.21
1.08
1.6
2.3
0.7
0.8
nmol/l
0.09
85
636
162
1632
0.86
1.06
9.5
10.7
1.2
1.3
%
0.59
162
1621
402
3219
1.10
1.06
1.6
1.9
—
—
—
0
0
110
806
1.20
1.06
2.1
2.0
10.4
10.4
mg/l
0.05
100
756
9
39
2.02
1.05
2.7
1.5
139.9
96.8
ng/l
—
9
39
43
282
1.34
1.03
1.0
1.0
—
—
—
0
0
118
873
1.19
1.03
1.1
1.1
18.4
13.3
au/ml
—
7
51
630
5153
1.08
1.03
1.7
1.6
—
—
—
0
0
69
748
0.80
1.02
1.4
1.5
94.5
141.7
pmol/l
0.45
64
730
394
3159
1.10
1.02
1.6
1.9
—
—
—
0
0
7
30
2.04
1.01
4.6
7.9
7.2
6.4
mmol/l
—
7
30
64
445
1.26
1.01
4.3
3.7
—
—
—
0
0
46
306
1.32
1.01
1.2
1.1
—
—
—
0
0
11
166
0.58
1.01
1.7
1.4
—
—
—
0
0
402
3229
1.10
1.00
1.6
1.9
—
—
—
0
0
13
66
1.72
0.99
1.0
1.1
—
—
—
0
0
13
66
1.72
0.99
1.0
1.1
—
—
—
0
0
13
66
1.72
0.99
1.0
1.1
—
—
—
0
0
50
338
1.30
0.99
3.7
3.0
366.3
770.3
e6/l
—
9
102
0
26
0.00
0.98
0.0
1.0
—
15.1
—
0
18
36
422
0.74
0.98
1.9
1.5
—
—
—
0
0
958
7966
1.06
0.98
5.3
4.4
91.2
92.1
%
0.53
934
7771
280
2212
1.11
0.97
1.3
1.3
46.9
43.0
au/ml
—
9
89
325
2589
1.10
0.97
3.5
3.9
—
—
—
0
0
3246
28881
0.95
0.97
3.8
3.4
1.2
1.3
mmol/l
0.84
3008
27001
303
2406
1.11
0.96
2.3
2.3
23.1
19.8
au/ml
0.21
15
156
58
636
0.80
0.96
1.3
1.3
—
—
—
0
0
32
203
1.38
0.95
1.2
1.1
1.7
1.9
nmol/l
—
7
42
1141
9547
1.06
0.95
4.4
3.2
27.3
73.5
e6/l
3.08
871
7220
1139
9535
1.06
0.93
2.5
2.4
—
—
—
0
0
50
341
1.29
0.93
1.2
1.3
86.7
257.4
titre
—
9
82
39
257
1.33
0.93
1.3
1.2
—
—
—
0
0
51
351
1.27
0.90
1.2
1.2
33.7
38.3
mg/l
0.40
41
288
63
445
1.24
0.90
1.6
1.8
—
—
—
0
0
44
297
1.30
0.90
1.2
1.1
—
—
—
0
0
164
1625
0.88
0.89
9.5
10.9
95.0
94.3
%
0.91
164
1617
886
7376
1.06
0.88
2.4
2.4
—
—
—
0
0
1275
11588
0.95
0.88
2.8
2.4
—
—
—
0
0
23
283
0.71
0.87
2.6
3.1
0.9
0.8
nmol/l
0.31
18
222
21
262
0.70
0.86
1.4
1.3
1.7
1.4
nmol/l
0.61
21
241
165
1627
0.88
0.84
9.4
10.8
0.7
0.7
%
0.04
165
1617
22
134
1.44
0.83
1.1
1.1
—
—
—
0
0
45
309
1.28
0.82
1.6
1.6
53.8
55.3
%
0.08
30
202
97
723
1.18
0.82
3.8
2.9
6.0
7.1
umol/l
0.63
77
564
32
210
1.34
0.81
1.1
1.1
426.7
386.3
nmol/l
0.48
25
196
248
2381
0.91
0.80
1.5
1.4
—
—
—
0
0
29
188
1.35
0.79
1.3
1.8
5.1
6.6
u/l
0.95
24
158
80
589
1.19
0.79
3.3
2.6
17.3
17.0
%
0.26
41
300
65
469
1.22
0.79
1.1
1.1
1.5
1.5
g/l
0.44
58
424
2405
20597
1.04
0.75
3.3
3.1
—
—
—
0
0
2607
22365
1.04
0.75
3.6
3.2
38.8
40.4
u/l
0.36
2449
21163
53
377
1.23
0.74
1.5
1.5
376.6
342.3
pmol/l
0.20
39
303
5
21
2.08
0.74
1.2
1.5
—
—
—
0
0
392
3197
1.08
0.74
1.6
1.9
—
—
—
0
0
103
781
1.16
0.73
7.0
3.8
7.4
7.4
ph
0.54
92
655
178
1401
1.12
0.72
8.1
12.2
—
—
—
0
0
864
7237
1.05
0.71
4.1
4.1
9.3
8.9
mg/mmol
0.08
530
4742
115
881
1.15
0.71
2.2
1.8
3.5
3.6
mmol/l
0.42
108
834
783
6542
1.06
0.71
3.6
2.6
5.8
7.0
e6/l
1.55
689
5719
211
2027
0.91
0.71
1.6
1.6
—
—
—
0
0
89
670
1.16
0.70
1.8
1.6
—
—
—
0
0
242
1939
1.10
0.70
2.1
2.2
5.1
7.2
ug/l
2.06
203
1720
9
126
0.62
0.70
2.2
2.3
—
—
—
0
0
15
88
1.49
0.70
1.4
1.4
—
—
—
0
0
5
23
1.90
0.70
1.2
1.3
—
—
—
0
0
5
23
1.90
0.70
2.4
1.2
—
—
—
0
0
24
155
1.36
0.69
1.3
1.1
—
—
—
0
0
10
53
1.65
0.68
1.4
3.2
—
—
—
0
0
12
67
1.57
0.68
5.7
4.7
—
—
—
0
0
7
105
0.58
0.68
1.0
1.3
—
—
—
0
0
181
1432
1.11
0.68
2.8
2.3
—
—
—
0
0
290
2738
0.92
0.67
19.4
18.3
1.3
1.2
inr
0.31
53
430
30
202
1.30
0.66
1.0
1.0
—
—
—
0
0
51
367
1.22
0.66
1.5
1.5
1.1
1.3
promille
0.43
43
280
58
423
1.20
0.66
1.1
1.1
—
—
—
0
0
57
415
1.20
0.66
1.0
1.2
1.8
9.2
u/ml
1.14
22
198
96
961
0.87
0.66
7.1
8.1
—
—
—
0
0
14
177
0.69
0.65
7.5
6.4
—
—
—
0
0
105
806
1.14
0.65
1.5
1.5
0.4
0.3
nmol/l
0.49
84
645
12
68
1.54
0.65
1.3
1.1
—
—
—
0
0
22
142
1.36
0.64
1.2
1.3
—
—
—
0
0
49
353
1.22
0.64
1.3
1.3
—
—
nmol/l
—
0
0
41
440
0.81
0.63
2.5
3.8
41.4
984.0
u/ml
0.98
36
410
60
442
1.19
0.63
1.0
1.2
1.7
3.7
u/ml
0.81
20
230
24
158
1.33
0.62
2.3
1.6
4.3
5.1
nmol/l
0.49
24
152
85
645
1.16
0.62
1.4
1.7
0.6
0.8
g/l
1.63
62
508
38
267
1.25
0.62
1.1
1.1
—
—
—
0
0
357
2926
1.07
0.62
2.5
2.4
43.9
52.1
u/l
0.18
306
2515
8
43
1.63
0.62
8.9
7.9
—
—
—
0
0
63
467
1.18
0.62
3.0
2.0
62.6
72.8
mmol/l
0.86
51
398
5
26
1.68
0.62
1.2
1.6
—
—
—
0
0
42
299
1.23
0.61
1.0
1.2
7.6
41.2
u/ml
0.67
26
211
11
62
1.55
0.61
1.7
1.5
463639.6
578267.0
nmol/l
0.07
11
46
93
712
1.15
0.61
1.1
1.1
—
—
—
0
0
1077
9109
1.04
0.61
3.0
2.6
—
—
—
0
0
13
164
0.69
0.61
1.8
1.4
—
—
—
0
0
11
143
0.67
0.60
1.1
1.1
—
—
—
0
0
13
77
1.48
0.59
4.0
2.8
—
—
—
0
0
87
665
1.15
0.59
10.2
4.9
—
—
—
0
0
40
285
1.23
0.59
1.3
1.2
—
—
—
0
0
606
5060
1.05
0.59
3.8
3.3
835.6
531.1
ng/l
0.40
398
3234
104
1024
0.89
0.58
6.6
4.9
—
—
—
0
0
64
480
1.17
0.56
2.1
1.7
—
—
—
0
0
64
480
1.17
0.56
2.1
1.7
—
—
—
0
0
52
383
1.19
0.56
1.3
1.3
—
—
—
0
0
12
71
1.48
0.55
1.1
1.1
—
—
—
0
0
64
481
1.17
0.55
2.1
1.7
—
—
—
0
0
64
481
1.17
0.55
2.1
1.7
—
—
—
0
0
8
108
0.65
0.55
2.1
2.5
—
—
—
0
0
8
110
0.64
0.54
3.3
4.9
—
—
—
0
0
8
110
0.64
0.54
1.6
2.5
—
—
—
0
0
9
52
1.51
0.54
1.1
1.1
71.8
69.2
ug/l
—
9
46
65
490
1.16
0.54
1.6
1.6
—
—
—
0
0
84
833
0.88
0.53
3.1
3.7
576.7
1765.3
u/ml
0.44
71
713
13
79
1.44
0.53
1.3
1.2
329.4
310.8
pmol/l
—
8
59
24
267
0.79
0.52
22.3
18.3
1460.3
1466.2
nmol/l
0.02
24
258
90
887
0.89
0.52
2.0
2.1
1.9
2.1
ug/l
0.10
77
799
33
234
1.24
0.52
2.8
2.7
—
—
—
0
0
26
179
1.27
0.52
1.1
1.1
205.5
220.9
iu/ml
0.11
26
179
335
3104
0.94
0.51
1.5
1.5
—
—
—
0
0
162
1300
1.09
0.50
1.6
1.7
—
—
—
0
0
832
7033
1.04
0.50
4.0
4.2
—
—
—
0
0
26
181
1.26
0.48
2.7
2.9
10.9
9.8
mg/l
0.48
20
156
808
6831
1.04
0.48
3.2
2.7
2549.8
3834.9
umol/l
0.66
728
6056
21
142
1.29
0.48
2.0
2.3
275.5
131.1
au/ml
—
6
18
19
215
0.77
0.48
1.1
1.1
—
—
—
0
0
13
81
1.40
0.48
6.1
5.6
—
—
—
0
0
16
185
0.76
0.47
1.6
1.4
5.7
5.5
mmol/l
0.28
16
178
7
42
1.46
0.47
1.4
2.2
—
—
—
0
0
24
262
0.80
0.46
15.8
13.1
817.5
818.5
nmol/l
0.00
24
254
205
1670
1.08
0.46
1.4
1.4
—
—
—
0
0
701
5917
1.04
0.46
4.6
4.3
1.7
2.3
ug/l
2.41
610
5380
50
376
1.16
0.45
2.5
2.0
292.0
286.6
mosm/kgh2o
1.10
40
304
807
7287
0.96
0.45
1.7
1.7
—
—
—
0
0
15
173
0.76
0.44
1.7
1.4
448341.3
123016.7
e6/l
—
8
97
179
1454
1.08
0.44
4.1
3.4
21.5
21.6
s
0.10
162
1271
73
718
0.89
0.44
2.5
2.0
—
—
—
0
0
5
27
1.62
0.43
1.8
3.1
—
—
—
0
0
5
27
1.62
0.43
1.8
3.2
—
—
—
0
0
5
28
1.56
0.42
7.6
6.3
—
—
—
0
0
480
4028
1.05
0.42
1.9
2.0
—
—
—
0
0
39
400
0.85
0.42
1.9
1.7
—
—
—
0
0
27
193
1.22
0.42
1.1
1.1
—
—
—
0
0
18
122
1.29
0.42
2.2
2.2
18.7
16.7
umol/l
0.28
18
122
29
209
1.21
0.42
2.4
2.7
40.9
41.4
%
0.04
13
66
42
314
1.17
0.42
1.2
1.4
0.2
0.6
u/ml
0.86
16
103
0
13
0.00
0.41
0.0
1.3
—
—
—
0
0
0
13
0.00
0.41
0.0
2.8
—
1.1
—
0
6
34
250
1.19
0.41
1.0
1.0
—
—
—
0
0
817
6938
1.04
0.40
3.2
3.4
1058.8
344.5
mg/l
1.74
493
4524
30
218
1.20
0.40
3.3
4.0
177.1
195.2
umol/l
0.12
17
134
11
69
1.40
0.40
1.0
1.4
—
—
—
0
0
0
16
0.00
0.40
0.0
1.1
—
0.1
—
0
8
37
275
1.18
0.40
1.3
1.5
—
—
—
0
0
48
365
1.15
0.39
1.4
1.2
—
—
—
0
0
10
62
1.41
0.39
1.5
1.6
—
—
—
0
0
9
58
1.36
0.38
1.4
1.4
—
—
—
0
0
34
252
1.18
0.38
1.3
1.3
75.9
165.3
pmol/l
—
8
81
39
293
1.17
0.38
17.4
7.1
11.0
11.3
%
0.32
39
293
5
32
1.37
0.37
1.0
1.0
—
—
—
0
0
47
359
1.15
0.37
1.5
1.9
—
—
—
0
0
36
270
1.17
0.36
1.7
1.5
—
—
—
0
0
6
36
1.46
0.36
1.0
1.0
—
—
—
0
0
5
69
0.63
0.36
2.0
1.3
46.6
55.0
%
—
5
59
121
979
1.08
0.35
2.2
1.8
395.8
470.0
mg/l
1.89
113
937
3064
27043
0.98
0.35
5.1
4.6
37.4
38.3
mmol/mol
6.86
2860
25333
55
427
1.13
0.35
1.3
1.4
—
—
—
0
0
1014
8668
1.03
0.35
4.2
3.6
0.0
0.0
estimate
0.03
346
3040
103
829
1.09
0.34
2.4
2.0
—
—
—
0
0
33
247
1.17
0.34
1.1
1.3
—
—
—
0
0
172
1600
0.94
0.34
2.2
2.9
49.8
45.9
u/ml
0.06
159
1550
6
39
1.35
0.34
1.0
1.0
—
—
—
0
0
398
3348
1.04
0.34
8.0
7.5
105.1
104.7
mmol/l
0.77
391
3278
10
64
1.37
0.33
7.3
8.5
—
—
—
0
0
6
76
0.69
0.33
2.0
1.3
—
—
—
0
0
77
613
1.10
0.33
1.2
1.2
—
—
—
0
0
47
364
1.13
0.32
1.0
1.1
0.7
1.9
u/ml
—
9
79
54
423
1.12
0.31
1.3
1.4
2.9
2.7
g/l
0.26
39
311
54
423
1.12
0.31
1.3
1.4
0.3
0.4
g/l
0.96
40
307
237
1975
1.05
0.31
2.9
2.5
—
—
—
0
0
54
424
1.12
0.30
1.3
1.4
6.4
6.6
g/l
0.28
39
312
117
954
1.07
0.30
1.9
2.6
526.6
378.4
ug/l
0.28
108
868
302
2535
1.04
0.30
1.6
2.0
—
—
—
0
0
13
89
1.28
0.30
1.1
1.5
—
—
—
0
0
48
469
0.89
0.29
2.8
2.5
—
—
—
0
0
13
143
0.79
0.29
1.4
2.1
163.8
159.3
nmol/l
0.03
13
125
14
97
1.26
0.29
2.4
1.5
—
—
—
0
0
16
113
1.24
0.29
1.8
1.7
—
—
—
0
0
32
243
1.15
0.29
1.3
1.2
—
—
—
0
0
45
352
1.12
0.27
3.3
3.9
534.8
98.6
u/ml
0.68
13
107
22
163
1.18
0.27
1.2
1.3
—
—
—
0
0
1054
9053
1.02
0.27
7.5
7.1
—
—
—
0
0
8
58
1.21
0.26
1.3
2.6
—
—
—
0
0
82
664
1.08
0.26
1.1
1.2
114.7
794.9
iu/ml
0.54
16
194
180
1498
1.05
0.26
4.7
5.3
—
—
—
0
0
18
131
1.20
0.26
1.1
1.1
—
—
—
0
0
5
64
0.68
0.26
4.0
2.0
—
—
—
0
0
34
263
1.13
0.25
1.6
3.5
56.5
54.2
%
0.26
29
174
41
322
1.11
0.24
9.9
4.4
6.1
6.9
mmol/l
1.53
33
263
265
2233
1.04
0.24
1.8
2.5
—
—
—
0
0
16
167
0.84
0.24
1.4
1.5
—
—
—
0
0
24
182
1.15
0.23
2.3
2.4
598.5
622.9
ml
0.11
17
123
5
33
1.33
0.23
1.0
1.2
—
1.0
—
0
5
104
856
1.06
0.23
1.3
1.3
—
—
—
0
0
7
82
0.75
0.22
1.0
1.8
279.4
48.2
u/l
—
7
77
5
35
1.25
0.22
1.2
1.2
—
—
—
0
0
31
241
1.13
0.22
1.1
1.2
24.9
15.0
u/ml
0.25
23
179
47
375
1.10
0.22
1.1
1.2
—
—
—
0
0
5
36
1.22
0.22
1.6
3.0
—
—
—
0
0
0
9
0.00
0.21
0.0
2.0
—
—
—
0
0
0
9
0.00
0.21
0.0
1.0
—
—
—
0
0
22
167
1.15
0.21
2.0
4.2
84.9
75.5
mg/l
0.13
22
136
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
12.3
—
0
5
5
37
1.18
0.21
1.2
1.2
—
58.5
—
0
15
8
89
0.79
0.21
1.0
1.2
—
—
—
0
0
21
159
1.16
0.21
1.3
1.3
128.8
134.7
nmol/l
0.33
21
159
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
8
91
0.77
0.21
1.5
2.1
—
—
—
0
0
8
92
0.76
0.21
1.6
1.3
—
—
—
0
0
72
674
0.93
0.21
1.1
1.1
—
—
—
0
0
0
12
0.00
0.20
0.0
2.1
—
60.0
—
0
7
31
243
1.12
0.20
4.5
4.0
2.0
1.4
ug/l
0.59
31
232
65
530
1.07
0.19
1.2
1.5
—
—
—
0
0
24
237
0.89
0.19
2.3
3.0
21.2
35.7
mg/l
0.53
19
177
59
554
0.93
0.19
2.4
2.5
132.9
120.5
ug/min
0.05
33
342
383
3268
1.03
0.18
1.5
1.4
—
—
—
0
0
320
2876
0.97
0.18
4.4
3.6
—
—
—
0
0
307
2612
1.03
0.18
8.1
8.3
1.2
1.4
mmol/l
1.54
293
2478
61
571
0.93
0.18
1.2
1.2
—
—
—
0
0
82
677
1.06
0.18
1.2
1.2
—
—
—
0
0
13
134
0.85
0.18
1.0
1.5
—
—
—
0
0
176
1485
1.04
0.17
7.1
7.3
24.5
24.3
mmol/l
0.32
166
1389
29
229
1.11
0.17
1.4
1.2
—
43.2
—
0
19
8
59
1.19
0.16
2.0
1.7
—
—
—
0
0
30
238
1.10
0.16
1.7
1.7
—
—
—
0
0
186
1573
1.04
0.16
1.1
1.1
—
—
—
0
0
21
163
1.13
0.16
1.1
1.1
32.3
213.9
ng/l
—
6
38
6
69
0.76
0.15
1.2
1.4
—
—
—
0
0
6
70
0.75
0.15
2.3
2.3
—
—
—
0
0
13
132
0.86
0.15
1.2
1.2
—
—
—
0
0
91
760
1.05
0.14
1.1
1.2
—
—
—
0
0
11
113
0.85
0.14
1.8
3.2
—
—
—
0
0
32
257
1.09
0.14
1.4
1.4
180385.3
56017.0
e6/l
0.46
22
179
25
198
1.10
0.14
1.4
1.1
—
—
—
0
0
10
73
1.20
0.14
1.9
1.1
—
—
—
0
0
3419
30013
0.99
0.14
4.0
3.7
5.6
5.7
mmol/l
2.47
3123
27716
74
616
1.05
0.14
1.7
1.7
24824.4
12596.8
e6/l
0.52
58
452
1228
10644
1.01
0.13
1.5
1.6
—
—
—
0
0
4121
35964
1.01
0.13
10.1
9.1
26.0
26.4
u/l
0.48
3971
34767
9
95
0.83
0.13
1.1
1.2
—
—
—
0
0
36
338
0.93
0.13
1.4
1.4
12.8
11.2
mmol/l
—
6
72
84
704
1.04
0.12
4.0
3.0
30.9
35.2
umol/l
1.23
76
618
81
679
1.04
0.12
2.7
3.2
25.4
24.4
mg/l
0.06
43
431
14
138
0.89
0.11
1.1
1.2
—
—
—
0
0
18
142
1.11
0.11
1.3
1.2
—
—
—
0
0
326
2902
0.98
0.11
2.2
2.3
8465.1
6207.5
u/l
0.44
100
971
13
100
1.14
0.11
1.8
2.8
23.4
30.5
umol/l
—
8
75
48
443
0.95
0.11
1.4
1.3
—
—
—
0
0
10
75
1.17
0.11
1.0
1.1
—
—
—
0
0
17
164
0.91
0.10
1.3
1.2
—
—
—
0
0
17
164
0.91
0.10
1.0
1.1
—
—
—
0
0
21
200
0.92
0.10
1.1
1.2
—
20.3
—
0
24
5
38
1.15
0.10
1.0
1.0
—
—
—
0
0
76
640
1.04
0.10
1.9
2.2
38.4
38.3
g/l
0.03
60
571
104
882
1.03
0.09
2.4
1.9
20.2
28.2
e6/l
0.24
81
673
5
40
1.09
0.09
8.6
6.3
—
—
—
0
0
20
190
0.92
0.09
1.3
1.2
—
—
—
0
0
24
195
1.08
0.09
1.5
2.2
2.8
3.6
mg/l
1.32
24
188
168
1438
1.02
0.09
1.9
2.5
—
—
—
0
0
50
418
1.05
0.09
2.3
1.7
—
—
—
0
0
104
884
1.03
0.09
2.4
2.0
514.6
5204.3
e6/l
0.58
82
712
6
49
1.07
0.08
1.8
1.6
—
—
—
0
0
291
2508
1.02
0.08
7.4
9.3
96.7
96.2
%
1.08
280
2420
5
56
0.78
0.08
1.4
1.2
—
—
—
0
0
34
282
1.05
0.08
3.1
2.9
—
18.3
—
0
5
14
111
1.10
0.07
1.1
1.0
—
—
—
0
0
85
722
1.03
0.07
2.6
2.2
131.9
133.1
g/l
0.21
67
564
40
334
1.05
0.07
1.3
1.4
—
—
—
0
0
265
2351
0.99
0.07
1.3
1.4
—
—
—
0
0
49
446
0.96
0.07
2.4
1.9
—
—
—
0
0
411
3634
0.99
0.07
1.3
1.2
—
—
—
0
0
9
77
1.02
0.07
1.3
1.5
—
—
—
0
0
80
719
0.97
0.06
2.2
2.4
—
—
—
0
0
1118
9728
1.01
0.06
2.0
2.0
—
—
—
0
0
28
232
1.06
0.06
4.3
4.1
100.6
112.6
au/ml
—
5
34
23
213
0.94
0.06
1.0
1.1
1397.2
1546.4
miu/ml
0.24
23
213
31
284
0.95
0.06
2.9
2.1
—
—
—
0
0
11
87
1.11
0.05
4.5
4.1
4.3
4.3
%
—
6
33
100
893
0.98
0.05
2.0
1.9
3.9
4.6
iu/l
0.28
31
327
162
1396
1.02
0.05
1.8
1.8
—
—
—
0
0
154
1327
1.02
0.05
8.7
11.9
24.3
24.1
mmol/l
0.53
147
1264
323
2799
1.01
0.05
7.1
8.7
13.6
13.3
kpa
0.60
309
2686
14
132
0.93
0.05
2.6
1.9
—
—
—
0
0
394
3419
1.01
0.05
1.8
1.8
—
—
—
0
0
323
2800
1.01
0.05
7.1
8.7
5.0
5.1
kpa
0.46
310
2686
54
459
1.03
0.05
1.5
1.6
—
—
—
0
0
28
234
1.05
0.05
1.6
1.5
32.3
36.6
%
0.21
18
149
37
312
1.04
0.04
3.5
3.6
—
—
—
0
0
67
598
0.98
0.03
1.2
1.3
4.0
4.6
u/ml
0.28
35
276
21
175
1.05
0.03
1.0
1.4
—
—
—
0
0
532
4630
1.01
0.03
2.7
2.8
2.4
2.4
mmol/l
3.05
454
4067
30
253
1.04
0.03
5.2
5.0
9.7
8.3
mg/l
0.52
20
207
70
601
1.02
0.03
1.8
1.6
1344.0
1074.3
titre
—
5
14
22
184
1.05
0.03
2.9
2.7
745.7
1039.9
u/ml
0.57
22
184
187
1650
0.99
0.03
1.2
1.3
236.6
217.9
miu/ml
0.27
85
804
269
2337
1.01
0.03
7.8
9.4
125.2
123.3
g/l
0.82
260
2254
24
202
1.04
0.02
3.6
2.2
1.0
2.0
u/field
—
9
114
321
2792
1.01
0.02
7.0
8.8
1.0
0.8
mmol/l
0.61
255
2162
36
307
1.03
0.02
1.1
1.1
280.8
290.7
mg/l
0.33
30
281
15
138
0.95
0.02
1.0
1.0
307.0
294.2
ng/l
—
10
92
103
910
0.99
0.02
1.2
1.2
—
—
—
0
0
15
137
0.96
0.01
1.0
1.0
1145.1
748.7
ng/l
—
7
89
76
658
1.01
0.01
1.1
1.1
—
—
—
0
0
397
3465
1.00
0.01
2.9
2.8
0.6
0.7
ug/l
1.72
229
2109
47
416
0.99
0.00
2.3
2.3
—
—
—
0
0
14
125
0.98
0.00
1.9
1.8
—
—
—
0
0
18
159
0.99
0.00
1.1
1.1
—
—
—
0
0
33
289
1.00
0.00
1.1
1.2
—
—
—
0
0
32
283
0.99
0.00
2.2
3.0
—
—
—
0
0
26
224
1.02
0.00
1.2
1.2
—
—
—
0
0
23
198
1.02
0.00
1.3
1.4
1497.5
2137.4
ml
—
6
30
25
215
1.02
0.00
3.1
2.1
—
—
—
0
0
53
464
1.00
0.00
3.5
2.6
—
—
—
0
0
19
165
1.01
0.00
2.4
2.5
3.2
1.9
mmol/l
0.41
13
127
18
160
0.98
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
5
52
0.84
0.00
1.0
1.1
0.0
2.9
u/ml
—
5
35
8
69
1.01
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
8
74
0.95
0.00
1.1
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
87.2
—
0
5
0
7
0.00
0.00
0.0
2.6
—
4.7
—
0
7
0
5
0.00
0.00
0.0
1.0
—
0.1
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
0.0
—
0
7

Mortality – FinRegistry

Association

Association between endpoint K11_DEEP_BITE and mortality.

Females

Parameter HR [95% CI] p-value
K11_DEEP_BITE 0.87 [0.65, 1.17] 0.356
Birth year 0.998 [0.99, 1.01] 0.553

During the follow-up period (1.1.1998 — 31.12.2019), 191 out of 65616 females with K11_DEEP_BITE died.

Males

Parameter HR [95% CI] p-value
K11_DEEP_BITE 0.7 [0.5, 0.97] 0.032
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 214 out of 71951 males with K11_DEEP_BITE died.

Mortality risk

Mortality risk for people of age

years, who have K11_DEEP_BITE.

N-year risk Females Males
1 0.086% 0.142%
5 0.51% 0.783%
10 1.324% 1.902%
15 2.632% 3.653%
20 4.629% 6.223%

Relationships between endpoints

Index endpoint: K11_DEEP_BITE – Deep bite

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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