No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
1382 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
484 |
4. Check minimum number of eventsNone |
484 |
5. Include endpointsNone |
484 |
6. Filter based on genotype QC (FinnGen only) |
461 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
Deep bite that required surgery
based on the number of shared cases.
Similar with more cases:
- Bilateral sagittal split ramus osteotomy operation
- LeFortI or BSSO operation
- Deep bite
- Anomalies of dental arch relationship, including avohilmo
- Dentofacial anomalies [including malocclusion]
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2875 | 1851 | 1018 |
| Only index persons | 2854 | 1841 | 1013 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.06 | 0.07 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 37.45 | 37.25 | 37.86 |
| Only index persons | 37.48 | 37.25 | 37.91 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 461 | 322 | 139 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.06 |
| Median age at first event (years) | 40.24 | 39.79 | 41.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 484
- Matched controls
- 4840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
132.5
307.7
166
19
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
303.3
307.7
366
49
EB1MA
NOMESCO Finland
Cephalometry with X-ray
154.2
307.7
266
38
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
238.5
307.7
322
40
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
199.0
307.7
296
38
K07.23
ICD-10 Finland
Deep bite
+∞
307.7
484
38
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
61.9
307.7
242
77
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
303.5
307.7
339
37
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
151.5
307.7
341
75
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
+∞
307.7
484
10
K07.13
ICD-10 Finland
Retrognaty, mandibular
1014.9
307.7
416
29
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
144.0
307.7
233
31
SBB10
NOMESCO Finland
Dental impressions
139.3
307.7
413
194
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
172.7
307.7
251
30
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
149.0
307.7
229
29
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
405.7
307.7
390
49
SJC10
NOMESCO Finland
Orthodontic band in one tooth
327.7
307.7
325
30
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
330.2
307.7
253
16
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
36.1
294.6
208
99
SAA04
NOMESCO Finland
Special examination of mouth
30.5
290.6
225
134
SXC05
NOMESCO Finland
Other oral or dental procedure
26.2
283.6
244
181
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
61.8
275.4
159
38
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
80.8
270.1
147
26
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
146.2
257.8
129
12
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
60.8
231.9
133
30
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
46.3
230.3
142
43
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
59.2
215.7
124
28
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
18.6
174.4
159
124
EBB10
NOMESCO Finland
Insertion of dental implant
60.4
170.8
97
20
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
11.4
165.2
261
450
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
26.4
141.4
103
49
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
13.2
132.2
147
155
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
79.0
126.2
68
10
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
40.8
117.8
73
21
EBB15
NOMESCO Finland
Insertion of dental implant abutment
71.0
113.2
62
10
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
42.2
112.6
69
19
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
42.3
107.9
66
18
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
9.1
106.6
162
253
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
14.3
106.2
106
93
SPC20
NOMESCO Finland
Implant borne crown
63.2
100.2
56
10
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
584.7
99.3
95
*
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
29.1
99.0
68
27
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
229.5
92.9
93
5
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
188.7
90.7
92
6
K07.24
ICD-10 Finland
Open bite
27.8
87.6
61
25
K07.60
ICD-10 Finland
Snapping jaw
8.9
86.2
126
185
SAA03
NOMESCO Finland
Extended examination of mouth
6.7
79.0
371
1598
WZC00
NOMESCO Finland
Treatment plan or consultation
5.7
77.2
315
1199
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
37.1
74.4
47
14
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
20.0
65.5
52
29
SXC03
NOMESCO Finland
Other oral or dental procedure
31.4
64.8
43
15
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
152.4
63.6
66
5
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.8
62.1
113
207
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
654.6
60.1
58
*
EEC05
NOMESCO Finland
Le Fort I osteotomy
141.8
59.4
62
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
4.7
58.7
330
1511
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
17.8
52.8
44
27
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
13.1
51.4
51
43
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
19.7
50.4
40
22
K00.00
ICD-10 Finland
Hypodontia
17.8
49.3
41
25
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
77.2
49.2
55
8
K07.10
ICD-10 Finland
Asymmetry of jaw
86.7
42.7
47
6
K01.0
ICD-10 Finland
Embedded teeth
11.4
42.6
46
44
EBA10
NOMESCO Finland
Operative extraction of tooth
4.1
42.0
155
504
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
10.3
40.4
47
50
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
217.5
39.5
40
*
Z3229
NOMESCO Finland
Other healthcare associate professional
6.1
39.4
75
141
K07.14
ICD-10 Finland
Retrognaty, maxillary
111.7
38.4
41
*
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
87.1
36.4
40
5
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
+∞
34.8
33
*
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
8.0
33.7
48
66
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
6.8
33.5
56
92
ZXE20
NOMESCO Finland
More than three and less than five hours
4.3
33.4
101
280
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
9.7
31.6
38
42
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
45.7
31.4
38
9
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
91.3
31.2
34
*
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
165.2
30.0
31
*
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
309.6
29.1
29
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
5.1
27.5
63
139
SPC10
NOMESCO Finland
Standard dental crown
11.0
26.5
29
28
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
3.3
24.7
116
427
SJE90
NOMESCO Finland
Orthodontic finishing
59.3
24.3
28
5
EB1WA, ,
NOMESCO Finland
33.0
24.0
31
10
ZXA10
NOMESCO Finland
Bilateral
3.3
24.0
108
387
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
35.4
23.6
30
9
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.1
23.5
53
115
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
87.8
22.9
25
*
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
9.8
22.8
27
29
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
126.0
22.8
24
*
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
5.7
21.0
41
78
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
115.0
20.7
22
*
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
17.3
19.9
31
19
OIKK, ,
NOMESCO Finland
7.5
19.7
29
41
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
24.9
18.8
26
11
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
18.7
154
753
EB1S1
NOMESCO Finland
Photography of teeth
31.5
18.5
24
8
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
22.8
18.4
26
12
J01CE02
ATC
phenoxymethylpenicillin; oral
2.8
17.4
397
3002
SAA02
NOMESCO Finland
Basic examination of mouth
2.8
17.0
398
3028
EDC30
NOMESCO Finland
Genioplasty
+∞
15.7
15
*
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.3
15.0
163
887
SPC09
NOMESCO Finland
Implant crown, demanding
154.5
14.5
15
*
SPC08
NOMESCO Finland
Implant crown
28.2
14.4
19
7
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
6.5
13.9
23
37
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
15.3
13.7
22
15
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
77.4
13.6
15
*
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
41.3
13.2
16
*
SPA02
NOMESCO Finland
Preparation for dental prosthetics
5.2
13.0
27
54
SAA01
NOMESCO Finland
Simple examination of mouth
2.5
13.0
405
3249
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.0
12.9
37
97
SDA02
NOMESCO Finland
Periodontal treatment, brief
2.0
12.8
214
1357
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
3.6
12.5
42
123
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
133.3
12.5
13
*
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
10.0
12.4
24
25
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
27.5
12.1
16
6
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
13.8
12.0
20
15
SPAT1324
SPAT
Screening procedure
2.1
11.9
142
792
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
11.7
185
1142
K07.33
ICD-10 Finland
Crowding of tooth or teeth
36.0
11.3
14
*
SPB20
NOMESCO Finland
Temporary bridge
20.6
11.2
16
8
SDA03
NOMESCO Finland
Periodontal treatment
1.9
11.2
235
1592
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.1
11.0
31
80
SCA02
NOMESCO Finland
Preventive oral health care
2.6
10.9
71
304
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.0
10.8
147
856
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
61.4
10.7
12
*
EDW99
NOMESCO Finland
Other operation on mandible
+∞
10.5
10
*
EMAK, ,
NOMESCO Finland
3.6
9.8
33
97
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
102.0
9.4
10
*
SCA01
NOMESCO Finland
Preventive oral health care, short
1.9
9.2
174
1123
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
19.0
9.0
13
7
N02BE01
ATC
paracetamol; systemic, rectal
2.5
8.9
432
3737
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
14.4
8.7
14
10
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.8
8.5
160
1025
EB1TW
NOMESCO Finland
3D modelling of dentition
28.1
8.5
11
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
8.5
29
86
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
8.5
225
1598
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
34.0
8.1
10
*
K07.68
ICD-10 Finland
Other disorders of the jaw joint
10.3
8.1
15
15
J01FF01
ATC
clindamycin; systemic
1.8
7.7
134
836
G50.1
ICD-10 Finland
Atypical facial pain
6.9
7.7
18
27
ECA30
NOMESCO Finland
Excision of lesion of gingiva
12.1
7.6
13
11
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
25.5
7.6
10
*
SCF02
NOMESCO Finland
Preventive oral care by dental hygienist
3.5
7.5
26
78
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
7.8
7.4
16
21
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
81.3
7.4
8
*
R06.5
ICD-10 Finland
Mouth breathing
2.4
7.3
53
238
K07.05
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
+∞
7.3
7
*
XX2XX, ,
NOMESCO Finland
+∞
7.3
7
*
N03AX16
ATC
[U] pregabalin
1.9
7.3
108
638
K07.61
ICD-10 Finland
Cracking jaw joint
3.9
7.2
21
56
L07
ICPC
Jaw symptom/complaint
7.2
7.0
16
23
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
40.6
6.8
8
*
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
40.6
6.8
8
*
WX704
NOMESCO Finland
Intubation
2.4
6.6
47
209
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
12.5
6.6
11
9
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
8.9
6.6
13
15
ECB10
NOMESCO Finland
Reconstruction of gingiva
70.7
6.4
7
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
6.3
6
*
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
6.3
6
*
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.8
6.3
19
52
TEG00
NOMESCO Finland
Punction of mandibular joint
27.1
6.2
8
*
M01AE01
ATC
ibuprofen; systemic, rectal
3.0
6.2
463
4261
WX402
NOMESCO Finland
General anaesthesia
1.8
6.1
105
647
H02AB06
ATC
prednisolone; systemic
1.6
6.1
207
1532
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
248
1803
1.77
8.65
2.0
2.4
—
—
—
0
0
208
1507
1.67
6.85
3.0
2.9
—
—
—
0
0
339
2858
1.62
5.50
3.5
3.6
6.90
9.01
mm/h
6.00
325
2701
120
848
1.55
4.01
3.5
3.0
1.02
1.02
kg/l
0.27
19
103
137
999
1.52
3.96
3.3
3.1
0.00
0.01
estimate
1.08
42
374
42
226
1.94
3.73
1.4
1.5
—
—
—
0
0
233
1917
1.42
3.50
3.0
2.9
0.00
0.00
estimate
0.50
45
394
232
1913
1.41
3.41
4.0
4.1
0.00
0.00
estimate
0.50
41
378
429
4009
1.62
2.87
7.9
10.8
3.94
3.93
mmol/l
0.29
422
3899
230
1933
1.36
2.85
3.0
2.9
0.00
0.00
estimate
-0.00
39
363
42
251
1.74
2.72
1.6
1.4
348.97
284.78
mu/l
0.37
37
224
426
3993
1.56
2.59
7.9
10.8
139.91
139.69
mmol/l
1.60
418
3897
85
613
1.47
2.53
1.4
1.6
71795308.92
40253132.86
pmol/l
0.17
78
554
20
96
2.13
2.46
1.1
1.1
0.41
3.18
u/ml
—
8
50
143
1143
1.36
2.36
2.2
2.7
13.80
20.58
ng/l
1.13
67
572
56
384
1.52
2.14
4.3
5.1
—
—
—
0
0
431
4085
1.50
2.10
8.6
10.6
17.62
20.10
mg/l
0.67
335
3101
119
951
1.33
1.94
1.5
1.5
—
—
—
0
0
398
3744
1.35
1.79
4.6
4.7
1.74
2.06
mu/l
0.51
385
3572
34
510
0.64
1.73
2.0
3.3
0.88
0.82
mmol/l
1.53
29
486
19
104
1.86
1.69
1.3
1.4
20.85
23.63
u/l
0.16
11
89
14
69
2.06
1.66
1.3
3.9
19.90
21.99
mg/l
—
8
47
24
144
1.70
1.60
1.0
1.1
7.94
1.68
u/ml
—
5
24
402
3807
1.33
1.57
3.4
3.6
5.54
5.72
mmol/l
3.95
388
3590
33
217
1.56
1.56
1.2
1.4
213.47
253.44
miu/ml
0.30
17
117
78
984
0.75
1.50
1.7
1.7
1.47
1.44
mmol/l
0.09
71
875
8
167
0.47
1.50
1.3
1.5
—
—
—
0
0
73
566
1.34
1.46
3.5
3.2
19.98
22.21
%
0.45
23
187
6
22
2.75
1.44
1.0
1.1
1386.00
1762.64
miu/ml
—
6
22
475
4660
2.04
1.42
13.8
15.6
40.73
40.86
%
0.16
450
4438
40
283
1.45
1.37
2.5
2.2
8051.29
3251.58
u/l
0.40
20
121
450
4358
1.46
1.34
7.9
8.7
27.51
27.59
u/l
0.03
441
4269
32
218
1.50
1.32
2.3
1.9
—
—
—
0
0
27
177
1.56
1.32
1.0
1.3
12.80
10.17
u/l
0.32
21
144
107
889
1.26
1.29
1.6
1.7
0.72
0.84
mg/l
0.37
74
664
21
131
1.63
1.25
1.1
1.1
—
—
—
0
0
104
867
1.25
1.22
2.1
2.1
—
—
—
0
0
15
87
1.75
1.16
1.5
1.8
—
—
—
0
0
404
3872
1.26
1.12
3.4
3.4
1.31
1.29
mmol/l
0.18
391
3690
28
396
0.69
1.11
1.4
2.3
23.54
24.93
%
0.18
23
345
305
2844
1.20
1.11
5.3
7.0
70.49
74.83
u/l
2.01
291
2709
8
41
1.97
1.09
1.8
1.4
—
—
—
0
0
217
1967
1.19
1.09
3.3
4.6
6.05
6.42
mmol/l
3.02
195
1801
338
3191
1.20
1.03
4.3
4.1
14.42
14.41
pmol/l
0.05
326
3007
93
785
1.23
0.99
2.1
2.0
—
—
—
0
0
85
711
1.24
0.98
3.9
3.1
1.46
1.51
ug/l
0.11
79
659
44
564
0.76
0.97
2.3
3.3
351.45
490.74
ng/l
0.14
22
356
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
17
109
1.58
0.94
1.9
1.9
204.29
223.49
pmol/l
0.29
17
103
54
431
1.28
0.92
2.9
2.3
0.60
0.65
ug/l
0.27
21
217
20
137
1.48
0.85
1.2
1.2
—
—
—
0
0
37
475
0.76
0.84
1.7
2.3
4.39
3.24
e6/l
0.36
22
226
6
32
1.89
0.82
1.0
1.1
—
—
—
0
0
104
1183
0.85
0.79
1.6
1.7
103.72
97.68
pmol/l
0.72
55
627
27
200
1.37
0.78
1.3
1.5
—
—
—
0
0
0
28
0.00
0.76
0.0
1.6
—
—
—
0
0
11
67
1.66
0.75
1.1
1.1
—
—
—
0
0
38
300
1.29
0.73
2.1
2.3
12.89
13.49
nmol/l
0.17
38
286
6
109
0.54
0.73
3.8
3.2
1.08
1.35
mg/l
—
6
102
5
25
2.01
0.73
1.2
1.5
5.62
6.33
mmol/l
—
5
25
10
60
1.68
0.72
1.5
1.9
7.01
7.70
mmol/l
—
10
60
44
355
1.26
0.72
1.3
1.3
30.68
27.82
iu/l
0.19
38
308
126
1128
1.16
0.71
2.1
2.6
54.52
55.97
u/l
0.19
116
1067
5
94
0.53
0.67
1.0
1.6
—
—
—
0
0
393
3808
1.17
0.67
6.5
9.0
91.46
91.90
ml/min/173m2
0.20
342
3107
208
1938
1.13
0.64
2.7
2.8
71.07
98.21
ug/l
3.03
201
1838
16
222
0.71
0.63
1.7
1.4
—
—
—
0
0
16
222
0.71
0.63
1.7
1.4
—
—
—
0
0
6
103
0.58
0.62
1.0
1.3
—
—
—
0
0
15
210
0.71
0.62
1.3
1.5
—
—
—
0
0
79
900
0.85
0.62
1.9
2.4
0.13
0.37
e6/l
2.38
62
667
0
20
0.00
0.60
0.0
1.7
—
—
—
0
0
12
80
1.51
0.60
1.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.7
—
—
—
0
0
7
113
0.61
0.58
2.0
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
25.59
—
0
23
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
121
1097
1.14
0.57
1.7
1.6
—
—
—
0
0
25
315
0.78
0.54
1.4
1.7
—
—
—
0
0
17
223
0.75
0.49
1.6
1.4
—
—
—
0
0
17
223
0.75
0.49
1.6
1.4
—
—
—
0
0
50
429
1.18
0.49
1.5
1.6
1134.02
1186.83
nmol/l
0.21
41
346
415
4062
1.15
0.48
3.9
3.9
3.05
2.93
mmol/l
2.38
402
3875
126
1365
0.90
0.47
3.5
5.8
1.22
1.22
mmol/l
0.09
117
1272
106
967
1.12
0.46
1.7
2.1
128.59
226.44
u/l
0.83
100
917
26
319
0.80
0.46
1.4
1.7
—
—
—
0
0
86
776
1.13
0.45
1.3
1.3
26.88
26.94
iu/ml
0.00
30
274
411
4026
1.14
0.44
3.7
3.7
4.97
4.84
mmol/l
2.03
399
3860
350
3399
1.11
0.44
3.4
3.6
—
—
—
0
0
6
93
0.64
0.42
2.2
2.2
160.85
305.78
ug/l
—
6
86
5
33
1.52
0.41
2.0
1.6
0.97
1.05
g/l
—
5
33
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
98
898
1.11
0.40
1.5
2.2
311.08
4738.30
umol/l
2.66
90
826
5
34
1.48
0.40
1.4
2.1
105.40
105.65
mmol/l
—
5
34
83
754
1.12
0.40
1.2
1.3
14.37
10.02
u/ml
0.23
48
317
43
373
1.17
0.39
1.8
2.1
385.14
372.38
nmol/l
0.11
37
351
5
36
1.39
0.38
1.2
1.3
193.12
192.95
pmol/l
—
5
36
10
136
0.73
0.38
1.7
1.6
—
—
—
0
0
16
202
0.78
0.37
1.6
2.1
71.76
68.22
g/l
2.68
16
190
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
67
605
1.12
0.36
1.8
2.8
671.86
580.42
ng/l
0.10
57
500
409
4018
1.12
0.36
3.7
3.7
1.51
1.48
mmol/l
0.75
397
3840
6
86
0.69
0.33
1.2
1.3
—
1.23
—
0
6
375
3673
1.09
0.33
9.9
12.7
14.44
14.25
%
0.27
370
3629
314
3061
1.07
0.29
2.7
2.9
49.12
40.71
u/l
0.30
304
2959
143
1357
1.08
0.29
2.8
4.7
38.07
37.05
g/l
1.79
136
1288
14
112
1.26
0.28
2.1
2.1
—
—
—
0
0
33
290
1.15
0.27
3.4
10.5
0.58
1.14
mmol/l
0.37
13
231
9
117
0.76
0.27
1.1
1.2
—
3.14
—
0
14
9
119
0.75
0.27
1.1
1.2
—
15.65
—
0
21
45
405
1.12
0.27
2.4
1.8
—
—
—
0
0
10
128
0.78
0.27
1.0
1.1
—
—
—
0
0
10
128
0.78
0.27
1.0
1.1
—
—
—
0
0
14
171
0.81
0.26
1.6
3.4
1.19
1.14
mmol/l
—
9
125
41
456
0.89
0.26
1.6
1.8
—
—
—
0
0
12
95
1.27
0.26
1.2
1.3
239.92
144.55
e6/l
0.21
12
75
12
95
1.27
0.26
1.1
1.3
2.33
5.56
e6/l
0.50
12
72
18
151
1.20
0.25
1.4
1.7
—
—
—
0
0
359
3525
1.07
0.25
3.9
4.3
36.98
38.19
mmol/mol
2.04
344
3366
32
283
1.14
0.25
1.6
2.3
81.07
75.17
ml/min/173m2
0.46
14
120
44
399
1.11
0.24
1.1
1.3
62.98
160.67
iu/ml
3.46
18
166
36
400
0.89
0.23
1.6
1.5
—
—
—
0
0
13
106
1.23
0.23
1.8
1.8
—
—
—
0
0
12
97
1.24
0.23
1.1
1.2
3.71
3.66
mmol/l
0.10
12
89
5
39
1.28
0.23
5.0
2.9
30.60
43.68
u/ml
—
5
39
19
163
1.17
0.22
2.1
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
15
177
0.84
0.21
1.7
3.3
5.15
5.12
kpa
0.08
15
171
0
12
0.00
0.21
0.0
3.6
—
—
—
0
0
0
12
0.00
0.21
0.0
3.6
—
—
—
0
0
10
123
0.81
0.20
1.6
1.7
—
256.00
—
0
5
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
15
128
1.18
0.18
3.2
2.2
0.64
0.65
%
0.05
15
128
91
866
1.06
0.18
1.9
2.0
—
—
—
0
0
14
163
0.85
0.17
2.0
1.3
—
—
—
0
0
76
801
0.94
0.17
1.9
2.0
2.72
2.77
mg/l
0.05
68
694
17
194
0.87
0.17
1.4
1.5
—
—
—
0
0
55
516
1.07
0.16
2.5
1.9
—
—
—
0
0
6
78
0.77
0.15
1.0
1.1
—
—
—
0
0
9
81
1.11
0.15
1.4
1.7
—
—
—
0
0
55
583
0.94
0.15
1.9
1.7
—
—
—
0
0
28
306
0.91
0.15
2.2
2.7
—
—
—
0
0
8
96
0.83
0.14
1.1
1.2
—
—
—
0
0
15
132
1.14
0.13
3.2
2.2
1.38
1.30
%
0.09
15
132
231
2272
1.03
0.11
5.8
8.8
3.66
3.94
e9/l
1.50
214
2005
114
1172
0.96
0.10
2.5
2.7
—
—
—
0
0
21
228
0.92
0.10
1.2
1.8
2.18
3.76
mg/l
1.12
14
161
158
1547
1.03
0.10
3.6
6.4
1.22
1.22
mmol/l
0.18
142
1329
194
1906
1.03
0.10
4.2
5.6
54.46
56.45
%
1.94
188
1813
5
48
1.04
0.09
1.0
1.2
—
—
—
0
0
181
1842
0.97
0.09
4.1
6.0
9.64
10.34
umol/l
0.73
173
1764
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
12
107
1.12
0.08
1.2
1.3
4.52
2.92
ug/l
0.51
12
97
5
64
0.78
0.08
1.0
1.5
—
—
—
0
0
7
80
0.87
0.07
1.6
2.7
—
—
—
0
0
80
819
0.97
0.06
2.9
3.8
6.13
11.11
mg/mmol
0.48
57
541
157
1548
1.02
0.06
1.9
2.3
78.20
74.00
nmol/l
1.22
151
1455
28
292
0.96
0.04
1.6
1.3
—
—
—
0
0
32
330
0.97
0.03
4.4
7.5
105.41
104.50
mmol/l
0.65
32
330
12
128
0.94
0.02
1.1
1.2
—
20.04
—
0
9
27
263
1.03
0.01
1.4
1.4
—
—
—
0
0
106
1052
1.01
0.01
1.4
1.3
0.81
1.49
u/ml
0.95
41
307
14
134
1.05
0.00
3.6
3.1
26.09
25.20
mmol/l
0.54
14
128
16
154
1.04
0.00
1.6
2.3
—
—
—
0
0
24
246
0.97
0.00
3.2
3.2
2.34
1.82
mmol/l
0.40
19
197
11
105
1.05
0.00
1.1
1.2
—
30.22
—
0
10
16
155
1.03
0.00
3.5
8.1
23.27
24.98
mmol/l
2.01
16
155
12
124
0.97
0.00
1.8
2.2
86.83
93.66
%
0.67
12
119
27
265
1.02
0.00
1.1
1.0
—
—
—
0
0
22
223
0.99
0.00
1.7
1.6
—
—
—
0
0
14
142
0.99
0.00
1.4
1.5
—
—
—
0
0
52
517
1.01
0.00
1.9
2.1
2.08
1.03
e6/l
0.47
37
271
37
368
1.01
0.00
2.8
3.4
29.00
31.42
%
0.78
32
275
24
241
1.00
0.00
1.5
1.4
—
—
—
0
0
142
1421
1.00
0.00
3.2
3.1
30.08
31.16
u/l
0.15
137
1358
128
1275
1.01
0.00
6.5
7.7
1.09
1.09
inr
0.01
39
407
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
12.72
—
0
5
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
7
78
0.90
-0.00
1.0
1.1
105.71
116.77
%
—
7
71
7
69
1.01
-0.00
1.6
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.7
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
8
86
0.93
-0.00
1.0
1.1
—
13.74
—
0
9
8
83
0.96
-0.00
1.0
1.1
—
—
—
0
0
8
85
0.94
-0.00
1.1
1.3
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.2
10.84
11.04
u/l
—
5
47
6
59
1.02
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
0.67
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint K11_DEEP_BITE_SURGERY and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_DEEP_BITE_SURGERY.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_DEEP_BITE_SURGERY – Deep bite that required surgery
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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