No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
725 |
4. Check minimum number of eventsNone |
725 |
5. Include endpointsNone |
725 |
6. Filter based on genotype QC (FinnGen only) |
689 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF10
Maxillary retrognathism
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12176 | 5755 | 6389 |
| Only index persons | 10270 | 4897 | 5373 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.16 | 0.18 |
| Only index persons | 0.19 | 0.18 | 0.21 |
| Median age at first event (years) | |||
| Whole population | 12.35 | 12.72 | 11.93 |
| Only index persons | 13.76 | 14.19 | 13.37 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 689 | 419 | 270 |
| Unadjusted period prevalence (%) | 0.14 | 0.15 | 0.12 |
| Median age at first event (years) | 27.85 | 25.76 | 31.08 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 725
- Matched controls
- 7250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
17.6
320.5
334
335
SBB10
NOMESCO Finland
Dental impressions
20.2
307.7
505
741
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
19.8
307.7
350
326
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
25.0
307.7
357
271
K07.14
ICD-10 Finland
Retrognaty, maxillary
+∞
307.7
725
*
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
220.8
307.7
217
14
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
20.9
307.7
295
230
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
27.4
307.7
316
199
K07.13
ICD-10 Finland
Retrognaty, mandibular
34.2
299.1
202
81
EB1MA
NOMESCO Finland
Cephalometry with X-ray
17.2
296.8
303
291
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
16.3
279.8
291
286
EEC05
NOMESCO Finland
Le Fort I osteotomy
1247.3
271.1
248
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
96.2
267.3
140
18
SJC10
NOMESCO Finland
Orthodontic band in one tooth
15.7
266.7
282
283
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
12.7
260.2
350
495
K07.24
ICD-10 Finland
Open bite
31.2
245.8
169
70
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
13.5
245.8
291
343
SAA04
NOMESCO Finland
Special examination of mouth
13.0
242.8
299
372
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
17.9
241.9
222
174
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
12.5
228.2
284
356
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
17.0
202.4
186
144
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
9.9
138.1
183
239
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
58.8
131.0
74
14
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
8.6
112.0
164
239
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
7.4
111.4
193
339
SXC05
NOMESCO Finland
Other oral or dental procedure
6.0
110.7
260
615
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
150.0
109.6
114
9
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
6.0
107.2
251
590
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
9.5
105.8
139
177
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.4
103.0
174
296
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
25.3
96.6
69
30
K07.10
ICD-10 Finland
Asymmetry of jaw
124.2
91.5
97
9
EBB10
NOMESCO Finland
Insertion of dental implant
24.1
90.7
66
30
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
6.2
84.5
172
349
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
187.1
81.0
83
5
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
6.0
80.8
169
351
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
9.2
80.1
104
129
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
5.6
79.2
180
403
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
6.4
75.7
142
265
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
5.8
75.3
163
348
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
32.8
75.3
49
16
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
37.7
73.6
46
13
K00.00
ICD-10 Finland
Hypodontia
10.4
70.2
82
88
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
6.0
69.7
141
282
EBB15
NOMESCO Finland
Insertion of dental implant abutment
38.0
69.0
43
12
WZC00
NOMESCO Finland
Treatment plan or consultation
3.6
63.7
433
2097
SAA03
NOMESCO Finland
Extended examination of mouth
3.9
61.9
521
2872
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
12.2
60.3
62
55
K07.60
ICD-10 Finland
Snapping jaw
5.7
58.5
122
249
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
5.5
53.2
115
242
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.3
52.5
119
261
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
11.0
50.8
56
55
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
46.3
454
2563
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
89.5
45.5
50
6
SJE90
NOMESCO Finland
Orthodontic finishing
16.4
45.5
39
25
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
5.7
43.9
87
168
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
8.8
41.6
54
66
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
15.7
41.1
36
24
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
11.7
38.3
40
36
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
108.5
38.1
41
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
10.8
38.1
42
41
K07.23
ICD-10 Finland
Deep bite
4.3
36.4
102
263
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
82.4
35.2
39
5
SPC20
NOMESCO Finland
Implant borne crown
40.4
33.8
42
11
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
91.9
32.0
35
*
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
47.7
26.7
32
7
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
7.7
26.5
38
52
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
4.8
25.0
58
128
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
25.4
24.6
34
14
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.4
23.4
93
303
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.8
23.3
76
217
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.5
22.9
38
61
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
33.5
22.6
29
9
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.8
22.5
73
208
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
215.9
20.7
21
*
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
26.4
20.6
28
11
K01.0
ICD-10 Finland
Embedded teeth
4.5
20.0
50
117
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.8
18.0
58
164
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.3
17.8
47
115
SAA02
NOMESCO Finland
Basic examination of mouth
2.5
17.4
616
5040
SPC10
NOMESCO Finland
Standard dental crown
13.0
17.3
30
24
K07.4
ICD-10 Finland
Malocclusion, unspecified
5.1
17.0
36
73
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
16.8
83
306
EB1WA, ,
NOMESCO Finland
14.7
16.4
27
19
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
41.1
16.4
20
5
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
21.5
16.1
23
11
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
16.0
104
442
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.4
16.0
118
533
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
34.2
15.8
20
6
SDA03
NOMESCO Finland
Periodontal treatment
1.9
15.8
316
2086
EDC30
NOMESCO Finland
Genioplasty
+∞
15.7
15
*
SXC03
NOMESCO Finland
Other oral or dental procedure
12.7
15.5
27
22
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
5.9
15.0
27
47
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
14.6
14
*
SPB20
NOMESCO Finland
Temporary bridge
36.9
14.5
18
5
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.1
14.4
25
42
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
14.2
201
1172
G47.3
ICD-10 Finland
Sleep apnoea
2.2
14.0
143
739
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
54.4
13.9
16
*
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
20.5
13.8
20
10
SAA01
NOMESCO Finland
Simple examination of mouth
2.1
13.7
595
4952
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
76.6
13.6
15
*
EEC02
NOMESCO Finland
Rapid expansion of maxilla
76.6
13.6
15
*
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.8
13.6
305
2063
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
34.8
13.5
17
5
OIKK, ,
NOMESCO Finland
2.5
12.8
84
358
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.0
12.7
36
93
F45.8
ICD-10 Finland
Other somatoform disorders
2.5
12.2
80
341
EFB50
NOMESCO Finland
Orthodontic procedure connected with ortognathic surgery
66.0
11.6
13
*
K07.61
ICD-10 Finland
Cracking jaw joint
3.8
11.2
34
92
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
25.5
11.2
15
6
EBA10
NOMESCO Finland
Operative extraction of tooth
1.9
11.1
171
1016
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
60.9
10.6
12
*
R06.5
ICD-10 Finland
Mouth breathing
2.4
10.6
75
331
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
10.4
248
1676
EMAK, ,
NOMESCO Finland
3.0
10.4
45
154
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
3.0
10.2
46
161
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
10.8
9.8
18
17
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
55.8
9.7
11
*
K05.30
ICD-10 Finland
Periodontitis complex
2.2
9.5
83
400
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
9.5
515
4277
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
9.7
9.3
18
19
SPAT1324
SPAT
Screening procedure
1.9
9.1
127
727
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
9.1
257
1805
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
9.0
179
1142
WZA90
NOMESCO Finland
Other medical or dental certificate
1.7
8.9
214
1438
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
8.8
178
1142
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
8.4
8.6
18
22
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
3.4
8.6
31
95
G50.1
ICD-10 Finland
Atypical facial pain
6.5
8.5
21
33
ZZH22
NOMESCO Finland
Graft of patients own bone, block
27.9
8.5
11
*
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
+∞
8.3
8
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
8.3
8
*
ZXA10
NOMESCO Finland
Bilateral
1.9
8.3
116
663
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.7
8.3
43
163
Z01.2
ICD-10 Finland
Dental examination
1.6
8.2
391
3093
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
2.7
8.2
45
176
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.7
8.1
42
159
EB1TW
NOMESCO Finland
3D modelling of dentition
11.9
8.1
14
12
R01AD58
ATC
fluticasone, combinations; nasal
1.7
8.0
200
1352
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
8.0
150
940
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
7.8
144
897
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.3
7.8
58
262
ECB17
NOMESCO Finland
Operation of gingival cleft
45.5
7.7
9
*
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
25.3
7.6
10
*
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
80.9
7.4
8
*
J34.2
ICD-10 Finland
Deviated nasal septum
2.5
7.4
45
185
EDC05
NOMESCO Finland
Segmental osteotomy of mandible
+∞
7.3
7
*
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
30.3
7.2
9
*
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
3.0
7.1
31
107
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
3.7
7.1
22
61
D82
ICPC
Teeth/gum disease
1.5
7.0
308
2363
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
3.9
7.0
20
52
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
13.9
6.9
11
8
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
6.9
348
2747
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.4
6.9
24
72
UDM02
NOMESCO Finland
Sinoscopy
3.7
6.8
21
58
Q35.1
ICD-10 Finland
Cleft hard palate
16.9
6.8
10
6
K03.30
ICD-10 Finland
Internal granuloma of pulp
16.9
6.8
10
6
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
22.7
6.7
9
*
M79.1
ICD-10 Finland
Myalgia
1.8
6.6
107
639
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.4
6.5
23
70
EEC40
NOMESCO Finland
Application of skeletal traction to maxilla
70.5
6.4
7
*
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
7.5
6.4
14
19
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
6.4
39
161
EEW99
NOMESCO Finland
Other operation on maxilla
+∞
6.3
6
*
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
26.9
6.2
8
*
H02AA02
ATC
fludrocortisone; oral
26.9
6.2
8
*
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
6.1
6.0
15
25
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.8
6.0
29
106
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
6.0
186
1314
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
123
768
1.72
6.54
1.5
1.5
493.63
9767195.82
pmol/l
0.50
100
686
266
2117
1.41
4.49
3.1
2.9
—
—
—
0
0
45
238
1.95
4.11
1.9
3.0
48.82
89.96
ng/l
2.53
39
212
114
796
1.51
3.79
3.7
3.4
877.86
595.81
ng/l
0.53
88
653
75
477
1.64
3.72
3.0
2.3
10.89
12.26
nmol/l
0.77
66
443
14
39
3.64
3.71
1.4
2.5
106.29
105.31
mmol/l
0.30
14
39
14
39
3.64
3.71
1.4
2.5
4.22
4.03
mmol/l
0.80
14
39
13
37
3.56
3.41
1.8
1.7
58.75
51.27
%
—
8
30
300
2534
1.31
3.18
2.9
2.6
—
—
—
0
0
219
1785
1.33
2.96
7.5
6.9
1.12
1.10
inr
0.16
91
585
164
1291
1.35
2.79
2.5
2.3
2.75
2.72
mg/l
0.06
148
1121
497
4536
1.30
2.78
4.7
3.8
14.50
14.41
pmol/l
0.38
452
4174
184
1491
1.31
2.55
2.0
2.6
175.30
57.31
u/l
0.47
173
1390
6
11
5.49
2.55
1.0
1.3
183.83
200.55
u/l
—
6
11
21
403
0.51
2.51
1.7
1.8
—
—
—
0
0
11
37
3.00
2.49
6.6
4.5
0.80
1.28
ug/l
0.86
11
37
314
2735
1.26
2.44
3.2
3.0
0.00
0.00
estimate
0.50
76
585
52
338
1.58
2.43
1.7
1.8
8.23
7.89
u/l
0.07
45
260
78
560
1.44
2.29
2.1
2.1
332.00
372.24
nmol/l
1.05
73
522
439
3998
1.25
2.23
4.5
3.8
8.42
8.73
mm/h
0.29
415
3723
179
1473
1.29
2.19
2.4
2.8
47.01
40.92
ng/l
0.10
92
750
22
396
0.54
2.17
11.0
8.5
1.33
1.34
mmol/l
0.03
22
385
312
2746
1.24
2.14
4.5
4.2
0.00
0.00
estimate
-0.00
76
578
9
207
0.43
2.10
22.7
10.2
22.42
24.34
mmol/l
—
9
201
74
539
1.42
2.03
1.3
1.3
117.36
153.45
iu/ml
0.52
34
208
436
3996
1.23
1.97
3.1
3.1
33.20
37.79
u/l
1.30
417
3831
313
2774
1.23
1.97
3.2
3.0
0.01
0.01
estimate
0.24
72
555
68
491
1.42
1.96
3.2
3.3
29.68
31.21
%
0.60
60
361
6
16
3.77
1.94
1.0
1.1
—
—
—
0
0
25
143
1.77
1.91
2.3
1.8
190.88
208.05
pmol/l
0.36
25
136
197
1671
1.25
1.85
2.1
2.4
—
—
—
0
0
5
12
4.19
1.82
1.4
2.8
—
—
—
0
0
561
5304
1.26
1.80
5.2
4.3
1.81
2.03
mu/l
0.49
522
4988
420
3868
1.20
1.69
6.0
6.7
76.77
82.01
u/l
1.25
403
3649
180
1528
1.24
1.67
2.1
2.2
—
—
—
0
0
77
589
1.34
1.61
1.5
1.6
1154.17
1155.16
nmol/l
0.00
60
468
170
1442
1.23
1.59
3.3
3.2
0.01
0.01
estimate
0.12
74
566
22
129
1.73
1.58
4.6
3.5
23.24
26.10
nmol/l
0.49
22
124
33
218
1.54
1.51
1.0
1.1
1.75
8.72
u/ml
—
6
38
149
1258
1.23
1.45
2.3
2.2
—
—
—
0
0
77
599
1.32
1.45
2.3
2.4
25.42
24.39
%
0.25
70
534
523
4949
1.20
1.45
3.5
3.2
1.25
1.25
mmol/l
0.03
497
4679
28
181
1.57
1.42
2.5
3.8
25.60
24.93
mmol/l
0.62
28
171
21
126
1.69
1.41
1.6
1.4
—
—
—
0
0
26
396
0.64
1.41
1.2
1.5
—
—
—
0
0
9
41
2.21
1.37
2.4
2.8
42200.00
41395.12
ug/l
—
9
41
34
232
1.49
1.36
3.1
2.4
0.17
0.13
e6/l
0.12
34
221
27
403
0.66
1.34
12.9
9.2
1.84
0.93
mmol/l
0.40
22
322
554
5287
1.20
1.32
3.6
3.7
—
—
—
0
0
53
396
1.37
1.32
1.7
1.7
12.59
16.44
iu/l
0.79
47
316
8
34
2.37
1.29
1.3
1.5
77.63
72.50
umol/l
—
8
34
271
2444
1.17
1.29
4.9
6.0
11.64
11.13
umol/l
0.22
263
2305
135
1144
1.22
1.28
1.9
2.3
0.67
1.20
mg/l
1.56
97
817
25
162
1.56
1.27
1.9
1.9
—
—
—
0
0
63
805
0.76
1.27
3.4
2.9
6.64
3.28
e6/l
0.45
33
425
546
5213
1.19
1.25
3.9
3.7
2.86
2.84
mmol/l
0.20
524
4938
6
25
2.41
1.24
1.2
1.3
—
—
—
0
0
15
85
1.78
1.23
1.4
1.1
—
—
—
0
0
11
56
1.98
1.22
1.6
1.2
—
—
—
0
0
24
359
0.66
1.22
1.2
1.4
—
—
—
0
0
24
358
0.66
1.21
1.2
1.4
—
—
—
0
0
24
358
0.66
1.21
1.2
1.4
—
—
—
0
0
24
358
0.66
1.21
1.2
1.4
—
—
—
0
0
216
1923
1.18
1.19
5.0
5.3
37.31
37.23
g/l
0.07
200
1806
37
507
0.72
1.19
1.8
2.5
38.70
124.96
u/l
0.44
30
429
11
57
1.94
1.17
1.6
1.2
—
—
—
0
0
630
6108
1.24
1.17
8.6
8.5
28.95
27.08
u/l
1.00
615
5926
5
20
2.51
1.15
1.4
1.9
—
—
—
0
0
23
342
0.66
1.15
1.8
1.6
—
—
—
0
0
541
5178
1.18
1.13
3.7
3.5
4.69
4.69
mmol/l
0.02
517
4931
112
1314
0.83
1.09
1.6
1.7
1.27
1.42
mmol/l
1.37
91
1161
537
5145
1.17
1.07
3.7
3.5
1.44
1.45
mmol/l
0.17
515
4882
521
4982
1.16
1.05
3.7
3.3
5.60
5.67
mmol/l
0.97
489
4639
18
276
0.64
1.05
1.6
1.4
—
—
—
0
0
109
926
1.21
1.02
1.4
1.2
12.69
26.57
iu/ml
3.75
34
297
249
2266
1.15
1.02
5.7
7.3
1.22
1.22
mmol/l
0.71
215
1980
472
4488
1.15
1.01
4.6
4.3
37.39
38.08
mmol/mol
1.01
445
4256
12
68
1.78
1.01
1.2
1.3
—
—
—
0
0
7
131
0.53
0.99
1.9
2.8
124.43
284.99
ug/l
—
7
118
9
49
1.85
0.99
2.3
1.8
115.89
139.62
ng/l
—
9
42
5
23
2.18
0.98
1.4
1.5
—
—
—
0
0
20
132
1.53
0.98
1.0
1.1
2.77
2.39
u/ml
—
8
60
32
234
1.38
0.95
1.3
1.4
—
—
—
0
0
5
104
0.48
0.89
2.4
5.0
349.20
392.63
umol/l
—
5
95
6
29
2.08
0.89
1.2
1.3
—
—
—
0
0
34
255
1.35
0.88
1.6
1.7
—
—
—
0
0
6
31
1.94
0.84
1.0
1.3
—
—
—
0
0
105
908
1.18
0.83
1.4
1.4
21.61
19.88
nmol/l
0.61
92
784
33
249
1.34
0.83
2.2
5.5
142.58
132.88
g/l
1.71
33
241
36
464
0.76
0.82
9.7
9.9
24.86
25.00
mmol/l
0.11
36
464
14
213
0.65
0.82
1.7
1.6
—
—
—
0
0
29
215
1.36
0.82
1.0
1.1
0.19
0.78
u/ml
2.90
15
123
164
1474
1.15
0.80
2.4
2.8
2.35
2.36
mmol/l
0.41
151
1336
15
98
1.54
0.79
4.5
3.4
14.71
29.93
mg/l
—
7
63
8
48
1.67
0.79
1.0
1.1
—
—
—
0
0
310
2902
1.12
0.78
2.9
2.9
86.30
80.25
ug/l
0.30
294
2723
122
1075
1.16
0.78
2.5
2.7
323.25
4395.19
umol/l
3.10
116
982
42
332
1.28
0.78
1.3
1.3
222.46
247.09
miu/ml
0.20
25
168
11
174
0.63
0.77
2.5
1.6
—
—
—
0
0
15
221
0.67
0.77
1.5
1.3
—
—
—
0
0
517
4988
1.13
0.75
8.7
8.8
94.71
95.31
ml/min/173m2
0.26
435
3907
9
53
1.71
0.75
1.2
1.4
145.71
194.63
pmol/l
—
9
53
26
193
1.36
0.74
1.6
5.7
0.70
0.64
%
0.51
26
193
200
1831
1.13
0.74
1.4
1.5
2.94
2.37
u/ml
0.14
50
468
95
825
1.17
0.73
1.7
1.9
—
—
—
0
0
32
246
1.31
0.73
1.5
2.3
3.00
8.99
ug/l
3.38
27
220
29
220
1.33
0.72
1.7
2.2
44.25
38.27
u/l
0.77
24
204
7
39
1.80
0.72
3.0
3.4
17.36
233.01
ug/l
—
7
33
578
5621
1.14
0.72
10.2
11.0
3.93
3.92
mmol/l
0.58
559
5436
32
247
1.31
0.71
1.2
1.2
2.89
4.15
u/ml
0.21
18
151
124
1103
1.15
0.71
1.8
1.5
—
—
—
0
0
21
152
1.39
0.69
1.4
1.3
—
52.78
—
0
9
21
152
1.39
0.69
2.1
1.8
—
—
—
0
0
11
69
1.60
0.68
1.2
1.3
—
—
—
0
0
356
3378
1.11
0.68
7.1
9.1
3.60
3.85
e9/l
1.58
331
2932
110
974
1.15
0.67
4.4
3.8
1.63
1.97
ug/l
0.45
97
888
576
5609
1.13
0.66
10.3
10.9
139.64
139.63
mmol/l
0.01
562
5447
559
5435
1.12
0.66
11.4
13.1
13.93
13.98
%
0.09
546
5340
7
44
1.60
0.65
2.1
2.0
0.11
0.16
nmol/l
—
7
36
313
2956
1.10
0.65
6.2
6.7
31.69
30.84
%
0.80
304
2820
17
120
1.43
0.65
4.9
4.3
49.76
55.00
%
1.66
17
120
688
6792
1.25
0.65
15.2
15.3
257.05
259.78
e9/l
0.53
676
6604
102
902
1.15
0.64
1.4
1.2
1.41
7.64
u/ml
4.34
58
363
136
1227
1.13
0.64
3.0
3.0
1.02
1.02
kg/l
0.28
19
155
12
79
1.53
0.63
1.8
2.6
15.78
17.28
%
—
5
41
29
226
1.29
0.62
1.1
1.1
2.48
7.82
u/ml
2.54
17
152
28
218
1.30
0.61
1.1
1.1
2.11
2.51
u/ml
0.10
15
138
81
707
1.16
0.61
2.1
3.4
29.45
29.74
s
0.18
76
691
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
15
105
1.44
0.60
1.4
1.3
—
—
—
0
0
60
700
0.84
0.59
1.4
1.5
—
—
—
0
0
12
174
0.68
0.59
1.0
1.2
—
—
—
0
0
24
184
1.31
0.58
1.9
1.7
—
234.29
—
0
7
7
114
0.61
0.58
1.0
1.3
—
—
—
0
0
6
35
1.72
0.57
1.2
1.1
1600.33
1614.03
miu/ml
—
6
35
6
35
1.72
0.57
1.3
1.2
—
92.17
—
0
6
6
35
1.72
0.57
3.3
3.1
18.67
45.71
u/ml
—
6
35
688
6800
1.23
0.57
15.2
15.2
4.65
4.60
e12/l
2.21
674
6601
687
6790
1.22
0.56
15.3
15.4
40.95
41.39
%
0.27
656
6452
307
2916
1.09
0.55
5.7
6.5
53.42
54.81
%
1.44
298
2777
59
682
0.85
0.54
1.4
1.5
—
—
—
0
0
142
1546
0.90
0.53
3.3
3.1
22.11
63.12
e6/l
1.32
121
1168
9
63
1.43
0.52
1.1
1.1
—
—
—
0
0
6
97
0.62
0.52
1.2
1.4
—
—
—
0
0
13
180
0.72
0.52
1.2
1.1
—
—
—
0
0
688
6806
1.21
0.51
15.3
15.4
138.45
137.04
g/l
2.02
683
6712
30
368
0.81
0.51
2.2
1.9
—
—
—
0
0
39
465
0.83
0.51
1.8
1.7
—
—
—
0
0
6
41
1.47
0.50
4.5
3.1
27.17
27.63
umol/l
—
6
41
40
475
0.83
0.50
1.8
1.8
—
—
—
0
0
25
198
1.27
0.50
1.6
1.6
—
—
—
0
0
13
93
1.41
0.48
2.5
2.9
5.10
4.90
kpa
0.52
13
93
15
111
1.36
0.47
1.7
1.8
—
1792.00
—
0
5
176
1642
1.09
0.47
1.7
1.7
103.45
97.89
pmol/l
0.72
101
865
75
669
1.14
0.45
2.5
2.6
2.41
2.42
mmol/l
0.38
69
582
124
1346
0.90
0.45
4.4
4.6
93.66
93.32
%
0.05
119
1311
311
2979
1.08
0.44
4.3
4.8
6.13
6.39
mmol/l
1.54
284
2717
233
2208
1.08
0.43
2.8
2.5
77.78
71.40
nmol/l
2.30
220
2046
17
131
1.30
0.42
1.4
1.4
307.19
316.60
ug/g
0.05
12
75
29
348
0.83
0.42
2.1
2.5
76.93
76.84
ml/min/173m2
0.01
15
149
28
231
1.22
0.41
1.4
1.4
—
—
—
0
0
5
33
1.52
0.41
3.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
2.2
—
—
—
0
0
133
1233
1.10
0.41
2.0
2.2
163.84
257.27
u/l
0.95
126
1172
8
59
1.36
0.41
1.9
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
5
34
1.47
0.40
1.0
1.7
—
964710.00
—
0
5
7
105
0.66
0.39
1.4
1.3
—
—
—
0
0
7
105
0.66
0.39
1.1
2.3
—
—
—
0
0
7
105
0.66
0.39
1.4
1.3
—
—
—
0
0
10
71
1.41
0.39
2.4
3.6
—
—
—
0
0
10
137
0.73
0.39
1.1
1.3
63.60
140.66
pmol/l
—
10
132
104
958
1.10
0.37
1.6
1.7
1.42
1.42
%
0.01
91
872
26
216
1.21
0.37
3.2
4.9
139.58
172.72
%
2.36
26
210
132
1414
0.92
0.37
3.1
3.1
0.48
0.31
e6/l
0.38
109
1053
5
37
1.35
0.37
1.8
1.8
—
—
—
0
0
601
5924
1.08
0.34
10.8
10.4
19.51
20.51
mg/l
0.31
458
4376
113
1051
1.09
0.34
2.5
2.6
6.28
7.61
e6/l
0.35
106
941
12
154
0.78
0.32
1.1
1.1
—
—
—
0
0
114
1065
1.08
0.31
3.6
4.2
7.22
11.10
mg/mmol
0.48
75
731
14
175
0.80
0.31
1.1
1.1
—
—
—
0
0
182
1910
0.94
0.30
3.3
3.3
32.16
31.09
u/l
0.21
175
1815
76
826
0.91
0.30
3.1
2.7
0.82
1.00
e6/l
0.30
45
447
19
157
1.22
0.29
1.6
1.6
0.22
0.33
nmol/l
1.37
13
127
23
195
1.19
0.28
2.4
2.1
—
—
—
0
0
33
289
1.15
0.28
1.4
1.7
—
—
—
0
0
43
478
0.89
0.27
1.4
1.3
—
—
—
0
0
5
73
0.68
0.26
3.4
2.9
—
1.25
—
0
9
5
73
0.68
0.26
1.0
1.1
—
—
—
0
0
46
508
0.90
0.26
9.2
7.4
104.50
104.63
mmol/l
0.05
46
508
9
74
1.22
0.25
1.0
1.1
—
—
—
0
0
6
81
0.74
0.24
1.2
1.6
3463.00
15583.67
e6/l
—
6
55
62
573
1.09
0.23
2.6
2.5
0.88
0.72
ug/l
0.39
27
312
106
1002
1.07
0.23
1.8
2.1
—
—
—
0
0
82
768
1.08
0.23
3.3
3.5
23.18
21.74
%
0.30
28
281
5
39
1.28
0.23
1.4
1.6
0.97
1.06
g/l
—
5
39
11
88
1.25
0.22
1.7
1.4
—
—
—
0
0
10
79
1.27
0.22
1.6
1.5
—
—
—
0
0
72
672
1.08
0.22
1.8
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
22
251
0.87
0.21
1.4
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
127.92
—
0
13
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
9
112
0.80
0.20
1.2
1.2
—
—
—
0
0
6
51
1.18
0.19
1.0
1.2
—
—
—
0
0
27
301
0.89
0.19
3.0
4.4
7.56
22.09
ug/l
0.47
22
236
15
175
0.85
0.19
1.2
1.6
261.60
103.36
u/ml
—
5
25
29
321
0.90
0.18
1.8
1.7
—
—
—
0
0
7
58
1.21
0.18
2.0
1.4
—
—
—
0
0
7
58
1.21
0.18
2.0
1.4
—
—
—
0
0
7
59
1.19
0.18
2.0
1.4
—
—
—
0
0
7
59
1.19
0.18
2.0
1.4
—
—
—
0
0
7
59
1.19
0.18
2.0
1.4
—
—
—
0
0
201
2069
0.96
0.17
5.9
7.1
1.22
1.22
mmol/l
0.52
181
1923
15
129
1.17
0.17
1.1
1.1
—
—
—
0
0
21
186
1.13
0.17
3.6
2.7
27.67
7.83
umol/l
0.57
15
145
8
73
1.10
0.15
2.3
1.7
—
—
—
0
0
6
76
0.79
0.15
1.2
1.8
—
—
—
0
0
6
76
0.79
0.15
1.2
1.8
—
—
—
0
0
76
722
1.06
0.15
5.1
5.7
0.84
0.82
mmol/l
1.52
71
687
67
634
1.06
0.15
3.1
3.5
6.25
7.46
umol/l
0.45
60
529
20
178
1.13
0.15
1.2
1.6
—
—
—
0
0
8
98
0.81
0.13
1.4
1.8
—
—
—
0
0
8
98
0.81
0.13
1.4
1.8
—
—
—
0
0
8
99
0.81
0.13
1.1
1.9
—
—
—
0
0
42
448
0.93
0.13
1.5
1.4
—
—
—
0
0
12
138
0.87
0.13
5.3
7.1
—
380.05
—
0
22
9
108
0.83
0.13
1.0
1.8
—
—
—
0
0
172
1763
0.97
0.12
3.2
3.2
—
—
—
0
0
358
3532
1.03
0.12
3.8
3.7
219.73
439.18
e6/l
0.24
11
39
28
259
1.08
0.11
1.7
2.1
22.20
38.22
u/ml
0.86
28
246
11
95
1.16
0.11
1.6
2.4
—
—
—
0
0
46
485
0.94
0.11
4.5
5.0
—
—
—
0
0
57
545
1.05
0.10
3.7
7.0
1.56
1.45
mmol/l
0.14
50
442
149
1456
1.03
0.10
3.4
3.7
8.41
8.69
mmol/l
0.26
134
1307
19
207
0.92
0.09
1.8
2.0
—
—
—
0
0
5
47
1.06
0.09
1.0
1.4
—
—
—
0
0
74
766
0.96
0.09
2.7
3.3
350.43
650.39
ng/l
0.60
35
447
5
60
0.83
0.08
2.8
1.6
—
—
—
0
0
5
63
0.79
0.08
1.0
1.1
—
—
—
0
0
5
65
0.77
0.08
1.0
1.1
172.20
237.30
mg/l
—
5
55
7
65
1.08
0.08
1.3
1.6
—
—
—
0
0
6
70
0.86
0.07
1.8
1.4
—
—
—
0
0
6
72
0.83
0.07
1.2
1.1
93.17
93.47
%
—
6
66
6
73
0.82
0.07
1.0
1.5
—
—
—
0
0
8
74
1.08
0.07
2.8
2.2
—
—
—
0
0
10
112
0.89
0.07
4.2
6.9
—
2051.43
u/ml
—
0
14
8
78
1.03
0.07
2.1
1.6
—
—
—
0
0
26
274
0.95
0.06
1.4
1.5
—
—
—
0
0
25
237
1.06
0.05
1.2
1.2
—
—
—
0
0
162
1638
0.99
0.04
1.6
1.5
1.87
2.01
g/l
0.67
108
998
21
219
0.96
0.03
1.4
1.5
201.81
193.83
u/ml
—
10
116
12
112
1.07
0.03
1.7
1.3
—
1.37
—
0
9
45
441
1.02
0.02
4.3
5.2
1.53
1.17
mmol/l
0.36
34
311
23
222
1.04
0.02
1.3
1.5
—
—
—
0
0
11
103
1.07
0.02
1.2
1.1
—
—
—
0
0
29
298
0.97
0.02
1.6
1.8
3.09
3.70
mg/l
0.20
21
211
47
478
0.98
0.01
1.0
1.0
—
—
—
0
0
42
427
0.98
0.01
2.7
2.5
—
—
—
0
0
10
96
1.04
0.00
1.2
1.2
118.70
116.36
%
—
10
87
16
165
0.97
0.00
1.1
2.6
451.63
449.06
mg/l
0.01
16
155
40
396
1.01
0.00
1.6
1.5
260.39
305.59
mu/l
1.00
33
355
54
544
0.99
0.00
2.2
2.4
1208.66
4854.98
u/l
1.83
19
208
13
129
1.01
0.00
2.0
1.8
—
—
—
0
0
203
2029
1.00
0.00
1.9
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
31.51
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
294.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
0.60
—
0
5
7
77
0.91
-0.00
1.0
1.1
—
—
—
0
0
16
160
1.00
-0.00
1.5
1.9
4.65
6.42
iu/l
—
6
59
5
49
1.02
-0.00
1.2
1.0
251.60
297.36
mg/l
—
5
44
8
89
0.90
-0.00
2.1
1.6
—
—
—
0
0
10
100
1.00
-0.00
2.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.4
—
26.00
—
0
8
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
73
0.96
-0.00
1.0
1.1
—
—
—
0
0
6
65
0.92
-0.00
2.3
1.6
—
—
—
0
0
5
56
0.89
-0.00
3.0
1.4
265.00
433.75
pmol/l
—
5
51
6
62
0.97
-0.00
2.2
1.7
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
13
130
1.00
-0.00
2.0
1.8
—
—
—
0
0
7
78
0.90
-0.00
1.7
1.6
—
—
—
0
0
6
64
0.94
-0.00
2.7
1.8
—
—
—
0
0
8
87
0.92
-0.00
2.5
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
5.85
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
10.50
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_RETROG_MAXILLAE and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_RETROG_MAXILLAE.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_RETROG_MAXILLAE – Maxillary retrognathism
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data