No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
716 |
4. Check minimum number of eventsNone |
716 |
5. Include endpointsNone |
716 |
6. Filter based on genotype QC (FinnGen only) |
716 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF10
Maxillary retrognathism
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12176 | 5755 | 6389 |
| Only index persons | 10270 | 4897 | 5373 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.16 | 0.18 |
| Only index persons | 0.19 | 0.18 | 0.21 |
| Median age at first event (years) | |||
| Whole population | 12.35 | 12.72 | 11.93 |
| Only index persons | 13.76 | 14.19 | 13.37 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 716 | 435 | 281 |
| Unadjusted period prevalence (%) | 0.14 | 0.15 | 0.12 |
| Median age at first event (years) | 27.66 | 26.10 | 30.07 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 636
- Matched controls
- 6357
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.14
ICD-10 Finland
Retrognaty, maxillary
+∞
323.0
636
*
SBB10
NOMESCO Finland
Teeth copy
24.7
262.8
444
543
EEC05
NOMESCO Finland
Le Fort I osteotomy
1006.4
223.4
206
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
26.0
218.5
328
250
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
33.9
207.1
279
143
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
20.2
185.5
304
275
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
194.0
180.4
181
13
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
18.3
168.9
286
271
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
22.3
168.4
260
191
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
14.1
159.2
312
407
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
20.0
156.8
252
202
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
18.3
150.1
250
217
EB1MA
NOMESCO Finland
Cephalometry with X-ray
16.4
148.7
262
261
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
16.1
143.4
253
250
K07.13
ICD-10 Finland
Retrognaty, mandibular
36.0
141.2
184
71
SAA04
NOMESCO Finland
Special inverstigation of mouth
13.9
139.7
267
314
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
14.3
132.5
247
270
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
21.7
126.5
193
125
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
94.8
118.6
129
17
SJC00
NOMESCO Finland
Bracket with fixed attachment
132.7
104.8
110
10
K07.24
ICD-10 Finland
Open bite
28.2
101.0
140
63
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
16.8
99.8
167
132
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
7.9
84.8
223
409
K07.10
ICD-10 Finland
Asymmetry of jaw
99.3
79.3
86
10
SXC05
NOMESCO Finland
Other oral or dental procedure
7.2
78.5
219
431
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
221.8
77.1
78
*
SJB60
NOMESCO Finland
External device grinding and adaptation
11.3
74.3
149
168
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
10.3
71.1
150
185
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
7.6
62.0
159
266
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
7.5
61.9
160
271
SAA03
NOMESCO Finland
Extended examination of mouth
4.0
58.2
452
2402
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
10.4
58.1
120
139
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
7.2
57.1
151
262
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
110.2
55.9
60
6
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
6.3
54.6
162
327
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.1
53.1
142
248
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.6
49.6
351
1633
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
12.9
48.8
89
79
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
6.7
46.6
128
229
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
29.0
46.5
63
24
K00.00
ICD-10 Finland
Hypodontia
16.4
46.5
76
52
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
6.7
45.9
126
225
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
6.2
45.2
133
260
EBB10
NOMESCO Finland
Insertion of dental implant
34.0
43.1
56
18
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
153.4
41.3
43
*
K07.60
ICD-10 Finland
Snapping jaw
7.2
39.6
102
165
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
39.5
390
2171
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
6.7
36.7
99
170
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
72.8
36.4
41
6
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
42.6
32.5
40
10
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.2
32.5
92
168
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
173.7
32.0
33
*
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
50.4
31.9
38
8
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
+∞
30.5
29
*
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
69.4
29.2
33
5
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
6.3
28.6
79
139
K07.23
ICD-10 Finland
Deep bite
5.2
28.4
94
206
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
15.9
28.2
46
31
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
10.1
26.8
54
58
EBB15
NOMESCO Finland
Insertion of dental implant abutment
30.8
26.6
35
12
SJA02
NOMESCO Finland
Plan for orthodontic care
97.5
25.9
28
*
SJA01
NOMESCO Finland
Estimation of need for orthodontic care
34.9
23.5
30
9
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
17.0
23.5
37
23
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
35.2
21.3
27
8
SAA02
NOMESCO Finland
Basic examination of mouth
2.6
20.9
528
4147
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
17.7
20.7
32
19
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
7.7
20.4
48
67
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
59.5
20.0
23
*
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
14.0
18.9
32
24
SJE90
NOMESCO Finland
Finishing face of orthodontick therapy
14.9
18.3
30
21
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
6.1
18.1
50
88
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
9.7
17.4
35
38
EB1WA
NOMESCO Finland
NA
20.7
16.5
24
12
SXC03
NOMESCO Finland
Other oral or dental procedure
17.3
16.2
25
15
SAA01
NOMESCO Finland
Simple examination of mouth
2.2
15.9
512
4124
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.7
15.5
69
200
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.9
15.5
99
374
SPB10
NOMESCO Finland
Production of temporary crone to tooth
21.7
14.7
21
10
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
153.4
14.5
15
*
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
43.5
14.2
17
*
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
43.5
14.2
17
*
SDA02
NOMESCO Finland
Parodonthologic therapy
2.0
14.0
247
1536
SPB20
NOMESCO Finland
Temporary bridge between two or more teeth
54.6
13.9
16
*
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
10.8
13.8
26
25
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
12.4
13.7
24
20
EEC02
NOMESCO Finland
Rapid expansion of maxilla
+∞
13.6
13
*
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.0
13.0
77
275
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
12.7
176
987
K01.0
ICD-10 Finland
Embedded teeth
4.6
12.6
43
98
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
24.9
12.5
17
7
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.4
12.5
45
108
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
38.3
12.2
15
*
EBA10
NOMESCO Finland
Surgical removal of tooth
2.2
12.2
140
723
EDC30
NOMESCO Finland
Genioplasty
47.6
11.9
14
*
G47.3
ICD-10 Finland
Sleep apnoea
2.3
11.5
115
555
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
122.1
11.5
12
*
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
122.1
11.5
12
*
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
20.5
11.2
16
8
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.8
11.1
232
1507
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
111.8
10.4
11
*
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
23.8
10.3
14
6
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
10.2
210
1346
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
8.3
9.9
21
26
F45.8
ICD-10 Finland
Other somatoform disorders
2.7
9.9
69
276
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
11.6
9.6
17
15
R06.5
ICD-10 Finland
Mouth breathing
2.7
9.5
64
251
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
101.5
9.4
10
*
EFB50
NOMESCO Finland
Orthodontic procedure connected with ortognathic surgery
101.5
9.4
10
*
K05.30
ICD-10 Finland
Periodontitis complex
2.7
9.4
66
265
K07.4
ICD-10 Finland
Malocclusion, unspecified
5.1
9.2
28
57
WZA90
NOMESCO Finland
Other doctors statement
1.8
9.1
188
1202
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
8.9
451
3730
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
11.8
8.6
15
13
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
10.2
8.6
16
16
OIKK
NOMESCO Finland
NA
2.4
8.4
74
333
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
+∞
8.3
8
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.0
8.3
32
84
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
8.3
162
1012
Q35.1
ICD-10 Finland
Cleft hard palate
33.8
8.1
10
*
EMAK
NOMESCO Finland
NA
3.3
8.1
39
123
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
3.2
8.0
40
129
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
3.2
7.9
40
131
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
11.0
7.8
14
13
ECB17
NOMESCO Finland
Operation for cleft gingiva
45.5
7.7
9
*
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
18.6
7.6
11
6
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
5.9
7.6
20
35
K07.61
ICD-10 Finland
Cracking jaw joint
4.2
7.6
27
66
N02BE01
ATC
paracetamol; systemic, rectal
1.6
7.4
462
3928
J34.2
ICD-10 Finland
Deviated nasal septum
3.2
7.4
37
121
EG1CG
NOMESCO Finland
Extensive MRI examination of mandipular joint with high intensity magnet
11.0
7.3
13
12
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
7.3
136
833
EEC40
NOMESCO Finland
Application of skeletal traction to maxilla
+∞
7.3
7
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
7.3
309
2381
ZZH22
NOMESCO Finland
Graft of patients own bone, block
20.3
7.1
10
5
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
7.0
224
1605
XX3DW
NOMESCO Finland
Time consuming IT work
2.6
7.0
48
191
T84.60
ICD-10 Finland
Gingivitis associated with dental implants
40.5
6.8
8
*
4361
FHL
Lip plastic or reconstruction due to cleft lip
70.5
6.4
7
*
UDC00
NOMESCO Finland
Ear microscopy
2.5
6.3
48
204
ZXA10
NOMESCO Finland
Bilateral
1.9
6.3
96
548
DLW00
NOMESCO Finland
Correction of cleft nose
+∞
6.3
6
*
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
+∞
6.3
6
*
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
+∞
6.3
6
*
DLD00
NOMESCO Finland
Reconstruction of cartilage of nose
27.0
6.2
8
*
N03AX12
ATC
gabapentin; oral
2.1
6.2
69
349
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
6.1
113
692
H02AB09
ATC
hydrocortisone; systemic
3.7
6.0
24
66
K06.00
ICD-10 Finland
Local gingivore traction
6.1
6.0
15
25
G50.1
ICD-10 Finland
Atypical facial pain
5.6
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
121
761
1.71
6.27
1.5
1.5
492.03
9867884.26
pmol/l
0.50
98
679
14
38
3.74
4.66
1.4
2.5
4.22
4.04
mmol/l
0.74
14
38
14
38
3.74
4.66
1.4
2.5
106.29
105.34
mmol/l
0.28
14
38
263
2094
1.40
4.44
3.1
2.9
—
—
—
0
0
45
235
1.98
4.26
1.9
3.0
48.82
90.65
ng/l
2.58
39
210
19
68
2.84
4.15
5.9
2.5
2.25
1.22
%
0.37
14
55
13
37
3.56
4.06
1.9
1.7
58.75
51.27
%
—
8
30
74
468
1.65
3.75
2.9
2.3
11.45
12.43
nmol/l
0.45
60
420
110
788
1.47
3.23
3.5
3.4
818.97
595.05
ng/l
0.40
86
644
296
2509
1.31
3.04
4.7
3.9
—
—
—
0
0
162
1273
1.35
2.79
2.5
2.3
2.72
2.70
mg/l
0.03
146
1103
311
2693
1.27
2.60
3.2
3.0
0.00
0.00
estimate
0.00
75
550
489
4489
1.28
2.46
4.6
3.8
14.51
14.41
pmol/l
0.41
444
4129
21
398
0.51
2.42
1.7
1.8
—
—
—
0
0
10
34
2.97
2.42
6.5
4.4
0.67
1.21
ug/l
—
10
34
50
328
1.56
2.26
1.7
1.8
8.22
7.95
u/l
0.05
44
253
180
1478
1.29
2.25
2.0
2.5
52.61
56.08
u/l
1.12
168
1374
309
2712
1.25
2.20
4.5
4.2
0.00
0.00
estimate
0.00
76
573
433
3947
1.25
2.17
4.5
3.8
8.44
8.75
mm/h
0.28
409
3675
75
545
1.42
2.08
2.1
2.0
333.67
373.64
nmol/l
0.99
70
507
25
140
1.81
2.03
2.3
1.8
190.88
208.23
pmol/l
0.37
25
133
176
1459
1.27
2.03
2.4
2.8
47.94
41.38
ng/l
0.10
89
738
310
2740
1.23
2.02
3.2
3.0
0.01
0.01
estimate
0.24
72
550
5
11
4.57
1.94
1.0
1.3
169.80
200.55
u/l
—
5
11
5
11
4.57
1.94
1.4
2.6
—
—
—
0
0
6
16
3.77
1.94
1.0
1.1
—
—
—
0
0
196
1658
1.25
1.89
2.1
2.4
—
—
—
0
0
430
3952
1.22
1.85
3.0
3.1
32.88
37.85
u/l
1.46
411
3788
67
494
1.39
1.74
3.2
3.3
30.00
31.23
%
0.44
57
355
33
211
1.59
1.71
1.0
1.1
1.75
8.72
u/ml
—
6
38
179
1516
1.24
1.70
2.1
2.2
—
—
—
0
0
21
119
1.79
1.68
4.5
3.6
23.87
26.76
nmol/l
0.48
21
114
553
5242
1.24
1.65
5.1
4.3
1.80
2.03
mu/l
0.52
515
4927
71
534
1.37
1.65
1.3
1.3
117.67
154.16
iu/ml
0.51
33
207
25
396
0.62
1.58
1.2
1.5
—
—
—
0
0
76
583
1.34
1.56
1.6
1.6
1154.17
1157.57
nmol/l
0.01
60
462
168
1428
1.23
1.54
3.3
3.2
0.01
0.01
estimate
0.12
74
562
76
586
1.33
1.52
2.3
2.5
25.77
24.47
%
0.33
69
521
34
228
1.52
1.46
3.1
2.4
0.17
0.14
e6/l
0.11
34
217
21
125
1.70
1.45
1.6
1.5
—
—
—
0
0
412
3821
1.18
1.44
6.0
6.6
74.67
81.24
u/l
2.74
395
3597
107
1297
0.79
1.41
1.6
1.7
1.28
1.42
mmol/l
1.16
86
1144
52
387
1.37
1.32
1.7
1.7
12.59
16.53
iu/l
0.81
47
310
61
785
0.76
1.29
3.5
2.9
6.85
3.35
e6/l
0.46
32
415
516
4902
1.19
1.28
3.4
3.2
1.25
1.25
mmol/l
0.02
491
4632
27
178
1.54
1.28
2.5
3.8
25.70
24.93
mmol/l
0.72
27
169
15
84
1.80
1.28
1.4
1.2
—
—
—
0
0
11
55
2.02
1.28
1.6
1.2
—
—
—
0
0
27
398
0.67
1.27
12.9
9.2
1.84
0.93
mmol/l
0.40
22
315
6
25
2.41
1.24
1.2
1.3
—
—
—
0
0
11
56
1.98
1.22
1.6
1.2
—
—
—
0
0
213
1891
1.18
1.22
4.8
5.2
37.35
37.22
g/l
0.13
197
1770
24
359
0.66
1.22
1.2
1.4
—
—
—
0
0
545
5211
1.19
1.22
3.6
3.7
—
—
—
0
0
5
19
2.64
1.22
1.4
1.9
—
—
—
0
0
24
358
0.66
1.21
1.2
1.4
—
—
—
0
0
24
358
0.66
1.21
1.2
1.4
—
—
—
0
0
24
358
0.66
1.21
1.2
1.4
—
—
—
0
0
145
1245
1.21
1.21
2.3
2.2
—
—
—
0
0
17
273
0.61
1.19
1.5
1.4
—
—
—
0
0
540
5165
1.19
1.17
3.9
3.7
2.85
2.84
mmol/l
0.14
513
4876
23
341
0.66
1.13
1.8
1.6
—
—
—
0
0
622
6036
1.23
1.10
8.5
8.5
28.69
27.04
u/l
0.85
607
5854
265
2411
1.16
1.10
4.9
6.0
10.65
10.82
umol/l
0.12
257
2272
20
128
1.58
1.09
1.0
1.1
2.77
2.40
u/ml
—
8
59
131
1129
1.20
1.06
1.7
2.3
0.68
1.02
mg/l
1.47
95
806
37
495
0.73
1.05
1.8
2.4
38.70
127.35
u/l
0.44
30
419
108
915
1.21
1.04
1.4
1.2
12.69
25.76
iu/ml
3.38
34
287
516
4938
1.16
1.02
3.6
3.3
5.60
5.68
mmol/l
0.90
484
4595
531
5098
1.16
0.99
3.7
3.5
1.44
1.45
mmol/l
0.13
507
4824
534
5129
1.16
0.99
3.7
3.5
4.68
4.69
mmol/l
0.05
509
4871
9
49
1.85
0.99
2.3
1.8
115.89
139.62
ng/l
—
9
42
5
23
2.18
0.98
1.4
1.5
—
—
—
0
0
32
233
1.39
0.97
1.3
1.4
—
—
—
0
0
0
31
0.00
0.96
0.0
1.2
—
195.86
—
0
31
13
210
0.61
0.96
1.5
1.6
—
—
—
0
0
466
4441
1.14
0.93
4.7
4.3
37.44
38.10
mmol/mol
0.94
439
4209
33
244
1.37
0.92
1.7
1.8
—
—
—
0
0
33
244
1.37
0.92
2.2
5.5
142.58
132.92
g/l
1.69
33
237
29
210
1.40
0.91
1.0
1.1
0.19
0.80
u/ml
2.87
15
118
6
28
2.15
0.91
1.2
1.3
—
—
—
0
0
7
129
0.54
0.88
1.9
2.7
124.43
288.81
ug/l
—
7
116
242
2219
1.14
0.88
5.7
7.2
1.22
1.22
mmol/l
0.57
208
1926
23
162
1.43
0.85
1.6
1.9
—
—
—
0
0
34
444
0.75
0.85
9.9
9.5
24.82
25.05
mmol/l
0.18
34
444
6
31
1.94
0.84
1.0
1.3
—
—
—
0
0
42
329
1.29
0.82
1.3
1.3
222.46
247.88
miu/ml
0.21
25
167
32
241
1.34
0.82
1.2
1.2
3.32
2.54
u/ml
0.10
15
116
15
97
1.56
0.82
4.5
3.4
14.71
29.83
mg/l
—
7
62
14
89
1.58
0.81
1.2
1.5
6.07
6.98
mmol/l
—
9
60
26
190
1.38
0.80
1.6
5.6
0.70
0.66
%
0.37
26
185
197
1794
1.14
0.79
1.4
1.5
3.00
2.39
u/ml
0.15
48
459
95
819
1.18
0.79
1.7
1.9
—
—
—
0
0
11
66
1.68
0.79
1.3
1.3
—
—
—
0
0
11
66
1.68
0.79
2.3
3.5
17.33
10.27
%
—
6
51
5
99
0.50
0.78
21.2
3.8
3.82
3.84
mmol/l
—
5
87
6
34
1.77
0.76
1.2
1.1
1600.33
1593.32
miu/ml
—
6
34
21
149
1.42
0.76
1.4
1.3
—
52.78
—
0
9
11
172
0.63
0.74
2.5
1.6
—
—
—
0
0
24
176
1.38
0.73
1.9
1.7
—
234.29
—
0
7
103
901
1.17
0.73
1.4
1.4
21.85
19.91
nmol/l
0.70
90
777
7
39
1.80
0.72
2.1
1.9
0.11
0.18
nmol/l
—
7
31
11
68
1.63
0.72
1.2
1.3
—
—
—
0
0
29
221
1.33
0.71
1.1
1.1
2.48
8.02
u/ml
2.61
17
146
350
3314
1.11
0.71
7.1
9.0
3.62
3.86
e9/l
1.47
326
2875
15
216
0.69
0.70
1.5
1.3
—
—
—
0
0
17
118
1.45
0.70
4.9
4.2
49.76
55.03
%
1.66
17
118
305
2869
1.11
0.69
2.9
2.9
85.39
80.67
ug/l
0.22
289
2690
161
1461
1.13
0.69
2.4
2.8
2.35
2.36
mmol/l
0.42
146
1315
570
5548
1.13
0.68
10.2
10.9
3.93
3.92
mmol/l
0.67
551
5362
307
2892
1.11
0.68
6.1
6.6
31.65
30.74
%
0.88
296
2747
120
1069
1.15
0.67
2.5
2.7
323.75
4457.73
umol/l
3.09
113
967
123
1100
1.14
0.66
1.8
1.5
—
—
—
0
0
12
78
1.55
0.66
1.8
2.6
15.78
17.22
%
—
5
40
509
4926
1.12
0.65
8.7
8.8
94.68
95.27
ml/min/173m2
0.25
426
3843
15
103
1.47
0.65
1.4
1.3
—
—
—
0
0
109
968
1.15
0.64
4.4
3.8
1.63
1.98
ug/l
0.45
96
882
60
703
0.84
0.62
1.4
1.5
—
—
—
0
0
8
49
1.64
0.62
1.0
1.1
—
—
—
0
0
679
6705
1.25
0.62
15.1
15.2
256.62
259.57
e9/l
0.60
667
6518
568
5538
1.12
0.61
10.2
10.8
139.64
139.63
mmol/l
0.03
554
5375
101
896
1.15
0.61
1.4
1.2
1.41
7.66
u/ml
4.33
57
362
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
12
174
0.68
0.59
1.0
1.2
—
—
—
0
0
79
691
1.16
0.58
1.9
3.4
29.30
29.72
s
0.28
74
675
29
364
0.79
0.58
2.2
1.9
—
—
—
0
0
6
35
1.72
0.57
3.3
3.1
18.67
45.71
u/ml
—
6
35
6
35
1.72
0.57
1.3
1.2
—
92.17
—
0
6
58
676
0.85
0.57
1.4
1.5
—
—
—
0
0
301
2852
1.10
0.57
5.7
6.4
53.59
54.95
%
1.35
291
2709
27
212
1.28
0.56
1.1
1.1
0.59
3.86
u/ml
—
5
51
10
65
1.55
0.55
2.4
3.5
—
—
—
0
0
6
38
1.58
0.54
3.3
3.4
18.32
240.22
ug/l
—
6
32
679
6713
1.22
0.54
15.1
15.1
4.65
4.60
e12/l
1.96
665
6516
17
125
1.37
0.54
1.4
1.4
307.19
313.13
ug/g
0.03
12
70
6
96
0.62
0.52
1.2
1.4
—
—
—
0
0
38
455
0.83
0.51
1.8
1.7
—
—
—
0
0
139
1510
0.90
0.50
3.3
3.1
22.25
64.56
e6/l
1.33
120
1138
121
1323
0.90
0.49
4.1
4.5
93.92
93.47
%
0.07
116
1290
39
463
0.83
0.49
1.8
1.8
—
—
—
0
0
30
244
1.24
0.49
1.5
2.3
3.11
9.03
ug/l
3.19
25
218
7
108
0.64
0.49
1.0
1.3
—
—
—
0
0
679
6719
1.20
0.48
15.2
15.3
138.44
137.08
g/l
1.89
674
6625
25
199
1.27
0.48
1.6
1.6
—
—
—
0
0
13
93
1.41
0.48
2.5
2.9
5.10
4.90
kpa
0.52
13
93
132
1212
1.11
0.48
3.1
3.0
1.02
1.02
kg/l
0.49
18
150
29
354
0.81
0.48
14.2
12.8
1.18
1.23
inr
—
9
59
15
111
1.36
0.47
1.7
1.8
—
1792.00
—
0
5
174
1625
1.09
0.45
1.7
1.7
102.91
98.00
pmol/l
0.61
99
855
13
174
0.74
0.43
1.2
1.1
—
—
—
0
0
27
221
1.23
0.43
1.4
1.3
—
—
—
0
0
74
662
1.13
0.43
2.4
2.6
2.41
2.42
mmol/l
0.37
68
575
177
1884
0.92
0.42
3.2
3.2
31.38
30.90
u/l
0.09
170
1789
5
33
1.52
0.41
3.0
1.6
—
—
—
0
0
5
33
1.52
0.41
1.0
1.7
—
964710.00
—
0
5
0
15
0.00
0.41
0.0
2.2
—
—
—
0
0
8
59
1.36
0.41
1.9
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
131
1215
1.10
0.40
2.0
2.2
165.02
258.67
u/l
0.94
124
1154
594
5843
1.10
0.40
10.7
10.4
19.54
20.51
mg/l
0.29
452
4312
7
102
0.68
0.39
1.1
2.3
—
—
—
0
0
10
137
0.73
0.39
1.1
1.3
63.60
140.66
pmol/l
—
10
132
536
5252
1.08
0.39
11.4
13.0
13.12
13.30
%
3.83
520
5152
29
344
0.84
0.38
2.1
2.6
76.93
76.95
ml/min/173m2
0.00
15
147
111
1026
1.10
0.37
2.4
2.5
6.40
7.71
e6/l
0.34
104
900
19
152
1.26
0.37
1.8
1.8
—
—
—
0
0
5
37
1.35
0.37
3.8
3.2
27.00
28.22
umol/l
—
5
37
5
37
1.35
0.37
1.8
1.8
—
—
—
0
0
23
189
1.22
0.36
2.4
2.1
—
—
—
0
0
19
153
1.25
0.35
1.6
1.6
0.22
0.33
nmol/l
1.41
13
125
129
1380
0.92
0.35
3.1
3.0
0.49
0.32
e6/l
0.38
107
1019
41
468
0.87
0.35
1.4
1.3
—
—
—
0
0
114
1059
1.09
0.35
3.8
4.4
7.22
11.10
mg/mmol
0.48
75
727
33
283
1.17
0.35
1.4
1.7
—
—
—
0
0
304
2931
1.06
0.34
4.3
4.8
6.15
6.39
mmol/l
1.36
276
2669
74
806
0.91
0.31
3.1
2.7
0.84
1.01
e6/l
0.29
44
437
7
98
0.71
0.31
1.4
1.3
—
—
—
0
0
7
98
0.71
0.31
1.4
1.3
—
—
—
0
0
227
2178
1.06
0.30
2.7
2.5
78.21
71.46
nmol/l
2.44
214
2016
102
951
1.08
0.30
1.5
1.7
1.41
1.42
%
0.02
89
864
8
62
1.29
0.28
1.1
1.1
—
—
—
0
0
12
150
0.80
0.27
1.1
1.1
—
—
—
0
0
5
73
0.68
0.26
3.4
2.9
—
1.25
—
0
9
9
73
1.24
0.25
1.0
1.1
—
—
—
0
0
24
208
1.16
0.24
2.7
4.9
134.58
172.65
%
2.84
24
203
195
2026
0.95
0.24
5.9
6.9
1.22
1.22
mmol/l
0.27
175
1872
14
169
0.82
0.24
1.1
1.1
—
—
—
0
0
5
39
1.28
0.23
1.4
1.6
0.97
1.06
g/l
—
5
39
11
88
1.25
0.22
1.7
1.4
—
—
—
0
0
15
125
1.20
0.22
1.1
1.1
—
—
—
0
0
10
79
1.27
0.22
1.6
1.5
—
—
—
0
0
105
995
1.06
0.21
1.8
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
61
568
1.08
0.20
2.6
2.5
0.90
0.72
ug/l
0.42
26
311
81
763
1.07
0.20
3.3
3.5
23.18
21.77
%
0.29
28
280
9
111
0.81
0.20
1.2
1.2
—
—
—
0
0
6
51
1.18
0.19
1.8
2.4
—
—
—
0
0
71
755
0.93
0.19
2.7
3.4
241.70
644.30
ng/l
1.04
33
444
7
58
1.21
0.18
2.0
1.4
—
—
—
0
0
7
58
1.21
0.18
2.0
1.4
—
—
—
0
0
7
59
1.19
0.18
2.0
1.4
—
—
—
0
0
7
59
1.19
0.18
2.0
1.4
—
—
—
0
0
7
59
1.19
0.18
2.0
1.4
—
—
—
0
0
11
91
1.21
0.17
1.6
2.4
—
—
—
0
0
29
320
0.90
0.17
1.8
1.7
—
—
—
0
0
22
247
0.89
0.17
1.4
1.4
—
—
—
0
0
15
173
0.86
0.17
1.2
1.6
261.60
103.36
u/ml
—
5
25
5
70
0.71
0.16
1.0
1.1
—
—
—
0
0
27
298
0.90
0.16
3.0
4.4
7.56
22.36
ug/l
0.48
22
233
8
70
1.14
0.16
2.3
1.7
—
—
—
0
0
6
80
0.75
0.15
1.2
1.6
3463.00
15724.74
e6/l
—
6
54
45
482
0.93
0.15
4.6
5.0
—
—
—
0
0
9
78
1.16
0.15
1.7
1.5
—
12.00
—
0
12
74
703
1.06
0.15
4.7
5.7
0.85
0.82
mmol/l
1.79
69
667
7
88
0.79
0.14
2.3
1.6
—
—
—
0
0
7
90
0.78
0.14
3.4
3.9
2.49
4.69
u/ml
—
7
78
8
98
0.81
0.13
1.1
1.9
—
—
—
0
0
9
106
0.85
0.13
1.0
1.8
—
—
—
0
0
42
447
0.94
0.12
1.5
1.4
—
—
—
0
0
69
660
1.05
0.12
1.7
1.8
—
—
—
0
0
28
259
1.08
0.11
1.7
2.1
22.20
38.22
u/ml
0.86
28
246
11
126
0.87
0.11
2.2
1.7
—
—
—
0
0
12
135
0.89
0.10
5.2
7.2
—
380.05
—
0
22
5
46
1.09
0.09
1.6
1.2
68.40
88.60
u/l
—
5
30
5
47
1.06
0.09
1.0
1.4
—
—
—
0
0
5
48
1.04
0.09
1.2
1.0
251.60
301.14
mg/l
—
5
42
169
1723
0.97
0.09
3.2
3.2
—
—
—
0
0
19
206
0.92
0.08
1.8
2.0
—
—
—
0
0
20
216
0.92
0.08
1.5
1.5
201.81
194.86
u/ml
—
10
114
352
3484
1.02
0.08
3.8
3.7
219.73
450.55
e6/l
0.25
11
38
5
61
0.82
0.08
1.0
1.1
172.20
204.11
mg/l
—
5
52
5
60
0.83
0.08
2.8
1.6
—
—
—
0
0
5
64
0.78
0.08
2.6
1.7
—
—
—
0
0
6
70
0.86
0.07
1.2
1.1
93.17
93.74
%
—
6
65
6
73
0.82
0.07
1.0
1.5
—
—
—
0
0
19
176
1.08
0.07
1.2
1.6
—
—
—
0
0
40
416
0.96
0.06
4.0
4.7
1.52
1.18
mmol/l
0.30
31
297
12
109
1.10
0.06
1.7
1.3
—
1.37
—
0
9
54
523
1.04
0.06
3.7
6.9
1.57
1.46
mmol/l
0.12
47
421
28
294
0.95
0.06
1.6
1.8
3.09
3.71
mg/l
0.20
21
203
26
273
0.95
0.05
1.4
1.5
—
—
—
0
0
146
1439
1.02
0.05
3.3
3.6
8.50
8.74
mmol/l
0.21
129
1269
11
100
1.10
0.05
1.2
1.1
—
—
—
0
0
24
228
1.05
0.05
1.3
1.2
—
—
—
0
0
10
110
0.91
0.05
4.2
7.1
—
2051.43
u/ml
—
0
14
159
1606
0.99
0.03
1.6
1.5
1.86
2.03
g/l
0.77
105
979
10
92
1.09
0.03
1.2
1.2
118.70
116.71
%
—
10
85
37
379
0.97
0.02
1.3
1.2
—
32.57
—
0
16
46
469
0.98
0.02
1.0
1.0
—
—
—
0
0
53
539
0.98
0.02
2.2
2.4
1233.27
4390.58
u/l
1.51
18
207
19
183
1.04
0.01
3.3
2.7
13.08
7.87
umol/l
0.25
13
142
584
5833
1.01
0.00
9.6
11.4
40.64
40.58
%
0.06
468
4856
12
124
0.97
0.00
2.1
1.8
—
—
—
0
0
16
158
1.01
0.00
1.1
2.4
451.63
435.10
mg/l
0.05
16
148
22
218
1.01
0.00
1.4
1.5
—
—
—
0
0
42
422
0.99
0.00
2.7
2.5
—
—
—
0
0
16
159
1.01
0.00
1.5
1.9
4.65
6.42
iu/l
—
6
59
200
1999
1.00
0.00
1.9
1.8
—
—
—
0
0
6
61
0.98
0.00
2.7
1.8
—
—
—
0
0
7
75
0.93
0.00
1.0
1.1
—
—
—
0
0
7
75
0.93
0.00
1.7
1.6
—
—
—
0
0
6
69
0.87
0.00
1.8
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.2
1.6
—
—
—
0
0
5
59
0.85
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
0.60
—
0
5
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
5.85
—
0
6
39
390
1.00
0.00
1.6
1.5
259.50
300.80
mu/l
0.86
32
349
0
7
0.00
0.00
0.0
2.3
—
31.51
—
0
7
62
620
1.00
0.00
3.0
3.5
5.64
7.53
umol/l
1.00
55
519
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
8
84
0.95
0.00
2.5
1.8
—
—
—
0
0
6
60
1.00
0.00
2.2
1.7
—
—
—
0
0
7
77
0.91
0.00
2.3
1.6
—
—
—
0
0
7
71
0.99
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
10.50
—
0
6
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
10
100
1.00
0.00
2.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_RETROG_MAXILLAE and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_RETROG_MAXILLAE.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_RETROG_MAXILLAE – Maxillary retrognathism
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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