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Benign neoplasm: other/unspecified salivary gland

DOID Endpoint Browser PheWeb

CD2_BENIGN_SALIVARY_NOS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D11.7, D11.9&
  • Hospital discharge: ICD-9 — 2102
  • Hospital discharge: ICD-8 — 2102
  • Cause of death: ICD-10 — D11.7, D11.9&
  • Cause of death: ICD-9 — 2102
  • Cause of death: ICD-8 — 2102

2 out of 7 registries used, show all original rules.

1014

4. Check minimum number of events

None

1014

5. Include endpoints

None

1014

6. Filter based on genotype QC (FinnGen only)

995

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7909 4345 3466
Only index persons 6218 3614 2604
Unadjusted period prevalence (%)
Whole population 0.11 0.12 0.10
Only index persons 0.12 0.13 0.10
Median age at first event (years)
Whole population 53.29 53.09 53.34
Only index persons 49.87 49.80 49.95

-FinnGen-

Key figures

All Female Male
Number of individuals 995 542 453
Unadjusted period prevalence (%) 0.20 0.19 0.21
Median age at first event (years) 52.14 49.40 55.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1014
Matched controls
10140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ELB30
NOMESCO Finland
Excision of submandibular gland
215.0
307.7
269
17
D11.70
ICD-10 Finland
Gland sublingual
6088.6
307.7
397
*
2102A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Major salivary glands
+∞
258.7
237
*
21020
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Salivary gland
+∞
246.2
226
*
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
25.0
220.3
161
76
4405
FHL
Partial removal of the parotid gland
918.2
163.4
156
*
D11.9
ICD-10 Finland
Benign neoplasm: Major salivary gland, unspecified
+∞
153.1
143
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
10.4
129.4
154
171
ELB40
NOMESCO Finland
Partial parotidectomy
18.1
90.1
74
44
EL4AT
NOMESCO Finland
Salivary gland cytology with ultrasound guidance
41.3
83.8
51
13
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.7
79.4
163
327
K11.2
ICD-10 Finland
Sialoadenitis
6.9
50.5
81
126
D11.7
ICD-10 Finland
Benign neoplasm: Other major salivary glands
+∞
46.2
44
*
4404
FHL
Complete removal of the parotid gland
+∞
39.9
38
*
EL3AE
NOMESCO Finland
Salivary gland ultrasound examination
15.5
37.5
33
22
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
10.1
34.0
39
40
D37.00
ICD-10 Finland
Aryepiglottic fold marginal zone
35.8
29.8
38
11
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
7.9
27.3
38
50
4403
FHL
Submandibular gland removal
55.4
23.1
27
5
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
85.4
22.8
25
*
ELB00
NOMESCO Finland
Excision or exploration of lesion of salivary gland
30.8
20.6
27
9
D11.71
ICD-10 Finland
Gland submandibular
+∞
18.8
18
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.0
17.2
50
131
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
14.4
16.9
28
20
C08.09
ICD-10 Finland
Malignant tumor of the submandibular or submaxillary gland, other or unspecified histology
61.0
15.8
18
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
7.1
15.3
23
33
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
14.5
278
1756
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
10.6
13.3
25
24
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
17.0
13.0
20
12
ELB50
NOMESCO Finland
Total parotidectomy
22.9
12.9
18
8
4704
FHL
Neck tumor removal
70.8
12.6
14
*
WX402
NOMESCO Finland
General anaesthesia
1.8
12.6
203
1212
K11.9
ICD-10 Finland
Disease of salivary gland, unspecified
12.6
12.1
21
17
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
8.8
12.1
25
29
EP1AE, ,
SPAT
5.3
11.6
23
44
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
15.7
10.8
17
11
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.8
373
2718
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.3
9.9
25
59
K11.5
ICD-10 Finland
Sialolithiasis
4.1
9.8
27
68
4701
FHL
Neck lymph node removal
37.0
9.0
11
*
C08.00
ICD-10 Finland
Malignant tumor of submandibular or submaxillary gland, not histology
37.0
9.0
11
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
9.0
379
2859
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
24.2
8.9
12
5
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.8
8.6
42
153
4402
FHL
Removal or exploration of a salivary change (eg ranula)
90.8
8.4
9
*
4409
FHL
Other measure in this category
+∞
8.3
8
*
C08.02
ICD-10 Finland
Cystic adenocarcinoma of the submandibular or submaxillary glands
33.6
8.1
10
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.5
7.9
19
43
S04
ICPC
Lump/swelling localized
1.9
7.8
98
538
K11.70
ICD-10 Finland
Hypoptyalism
10.1
7.5
14
14
ZXA05
NOMESCO Finland
Left side
1.5
7.5
261
1877
C82.1
ICD-10 Finland
Follicular lymphoma grade II
7.7
7.4
16
21
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
11.0
7.3
13
12
ELB99
NOMESCO Finland
Other excision of salivary gland
+∞
7.3
7
*
C07.70
ICD-10 Finland
Malignant tumor of the superficial part of the parotid gland
30.2
7.2
9
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
7.0
253
1829
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
5.9
6.9
18
31
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
4.0
6.9
19
48
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
9.4
6.8
13
14
ZXA00
NOMESCO Finland
Right side
1.5
6.8
278
2062
8200/3-C08.0
ICD-O-3
Adenoid cystic carcinoma of submandibular gland
40.3
6.8
8
*
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
2.4
6.6
43
182
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
10.1
6.5
12
12
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
3.7
6.5
20
55
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
6.4
105
627
C08.90
ICD-10 Finland
Malignant tumor in unspecified large salivary gland without histology
+∞
6.3
6
*
8430/3-C08.0
ICD-O-3
Mucoepidermoid carcinoma of submandibular gland
+∞
6.3
6
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
6.1
58
289
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
5.6
6.0
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
140
215
7.39
89.30
1.4
1.2
—
—
—
0
0
39
111
3.61
11.93
2.6
1.7
1.47
0.84
g/l
0.66
32
86
137
746
1.97
11.16
1.5
1.4
—
—
—
0
0
558
4661
1.44
7.38
9.3
8.9
4.23
4.17
e9/l
0.21
495
4074
482
3956
1.42
6.82
6.1
5.5
0.61
0.59
e9/l
0.37
419
3402
483
3967
1.42
6.80
6.1
5.5
0.04
0.04
e9/l
0.14
419
3417
455
3705
1.41
6.70
6.5
6.2
—
—
—
0
0
495
4100
1.41
6.56
6.2
5.8
0.20
0.19
e9/l
0.63
429
3587
489
4045
1.40
6.51
6.2
5.6
2.16
1.89
e9/l
0.43
433
3562
405
3243
1.41
6.50
2.2
2.2
—
—
—
0
0
443
3604
1.41
6.49
6.5
5.7
0.73
0.67
%
1.81
414
3350
456
3758
1.39
6.06
6.3
5.6
57.48
57.69
%
0.12
429
3514
451
3725
1.38
5.85
6.4
5.7
3.04
2.84
%
0.94
422
3466
460
3816
1.38
5.79
6.6
5.8
27.08
27.15
%
0.04
435
3563
22
70
3.19
5.76
1.8
1.4
—
—
—
0
0
452
3744
1.37
5.72
6.7
6.0
8.82
8.74
%
0.23
423
3489
151
1054
1.51
4.86
1.3
1.3
—
—
—
0
0
441
3733
1.32
4.49
5.1
4.7
35.01
35.09
g/l
0.10
416
3465
314
2555
1.33
4.14
3.3
3.4
28.34
101.06
e6/l
1.90
247
2009
492
4270
1.30
4.02
8.0
6.6
1.21
1.21
mmol/l
0.32
426
3625
34
163
2.12
4.01
4.3
2.6
—
—
—
0
0
316
2592
1.32
3.90
2.6
2.4
56.56
90.88
u/l
0.57
293
2390
14
46
3.07
3.54
5.2
5.7
—
—
—
0
0
499
4385
1.27
3.53
6.3
6.1
10.81
11.51
umol/l
1.18
475
4158
186
1430
1.37
3.52
2.8
2.8
1.12
1.12
e6/l
0.01
120
835
285
2337
1.31
3.47
3.2
3.2
0.30
0.51
e6/l
1.73
221
1813
350
2951
1.28
3.44
3.7
3.8
52.66
104.81
e6/l
1.25
259
2151
130
952
1.42
3.28
2.0
1.7
—
—
—
0
0
275
2263
1.30
3.23
3.0
3.2
—
—
—
0
0
175
1351
1.36
3.22
3.3
3.1
0.81
0.82
mmol/l
0.47
165
1257
148
1123
1.37
3.03
6.3
5.2
1.02
1.03
mmol/l
0.33
140
1025
158
1216
1.35
2.96
2.2
2.0
—
—
—
0
0
617
5625
1.25
2.94
4.7
4.5
—
—
—
0
0
132
988
1.39
2.94
1.4
1.3
586.21
487.65
titre
0.23
29
230
444
3918
1.24
2.82
6.7
5.9
1.21
1.21
mmol/l
0.26
405
3555
109
796
1.41
2.81
4.3
3.4
2.28
2.01
mmol/l
0.40
96
649
107
784
1.41
2.71
2.4
2.6
5.50
6.94
ug/l
0.60
95
685
12
40
3.02
2.70
1.8
1.6
40.42
37.79
%
0.22
12
40
684
6343
1.24
2.64
8.3
7.6
81.32
79.68
u/l
0.29
640
5938
111
823
1.39
2.63
4.6
3.4
—
7.37
—
0
5
169
1339
1.31
2.61
2.9
3.0
2.35
2.35
e6/l
0.00
104
749
600
5498
1.22
2.55
5.0
4.7
1053.64
2835.42
e6/l
0.75
11
93
13
50
2.62
2.54
2.4
3.4
—
—
—
0
0
542
4918
1.22
2.53
5.2
4.7
7.01
6.75
mmol/l
1.99
515
4619
221
1821
1.27
2.53
2.7
2.6
5.90
5.50
e6/l
0.17
187
1657
301
2586
1.23
2.37
2.4
2.2
202.51
236.08
u/l
0.33
278
2435
97
719
1.39
2.32
1.5
1.5
—
—
—
0
0
17
79
2.17
2.25
1.4
1.1
—
—
—
0
0
22
114
1.95
2.21
2.7
2.5
—
—
—
0
0
82
596
1.41
2.21
2.9
3.0
10.15
10.57
g/l
0.37
75
547
0
55
0.00
2.07
0.0
1.1
—
295.12
—
0
48
198
1651
1.25
2.04
4.6
3.9
253.97
351.61
ng/l
0.43
164
1357
207
1735
1.24
2.03
3.1
3.0
526.83
541.28
mosm/kgh2o
0.45
173
1501
337
2968
1.20
2.03
3.6
3.5
2.34
2.36
mmol/l
0.75
298
2588
242
2066
1.23
2.00
7.1
6.6
—
—
—
0
0
51
346
1.50
1.98
1.2
1.5
—
9.46
—
0
7
426
3842
1.19
1.96
2.7
2.6
—
—
—
0
0
377
3365
1.19
1.95
2.3
2.3
77.70
78.49
nmol/l
0.22
338
2981
89
672
1.36
1.93
4.6
3.7
98.03
88.60
ng/l
0.43
75
588
18
92
1.97
1.91
1.2
1.3
—
—
—
0
0
292
2552
1.20
1.89
4.5
4.0
7.39
7.40
ph
0.84
52
491
150
1222
1.27
1.89
3.0
2.5
2.26
2.31
g/l
0.54
137
1131
170
1406
1.25
1.88
1.4
1.5
2.37
2.55
g/l
0.63
100
817
621
5796
1.18
1.87
4.3
4.1
—
—
—
0
0
128
1028
1.28
1.81
6.9
7.1
4.99
5.12
kpa
0.79
120
983
439
3990
1.18
1.80
4.4
3.9
0.00
0.01
estimate
0.80
71
715
9
35
2.59
1.80
1.0
1.2
—
2.00
%
—
0
7
128
1029
1.28
1.80
6.9
7.1
11.76
11.99
kpa
0.18
121
985
161
1331
1.25
1.79
3.1
2.5
11.51
12.69
umol/l
1.30
147
1243
77
576
1.36
1.79
9.7
7.1
24.84
24.65
mmol/l
0.15
71
551
128
1030
1.28
1.79
6.9
7.1
1.93
1.31
mmol/l
0.87
100
824
53
373
1.44
1.75
2.5
1.9
4.41
2.09
ug/l
0.35
48
334
14
68
2.07
1.70
2.2
2.1
2.20
2.33
u/field
—
5
24
81
617
1.34
1.69
5.9
4.6
—
—
—
0
0
305
2702
1.18
1.68
3.6
3.3
—
—
—
0
0
18
97
1.87
1.67
1.1
1.5
69.28
64.67
%
—
8
64
91
707
1.32
1.66
5.8
7.9
—
—
—
0
0
296
2618
1.18
1.66
3.1
3.1
6.94
7.19
mmol/l
0.45
242
2184
29
181
1.62
1.65
2.9
2.5
16.13
16.07
%
0.02
17
91
432
3943
1.17
1.64
5.8
5.2
0.00
0.00
estimate
-0.00
73
737
387
3504
1.17
1.63
11.4
9.6
0.00
0.00
e9/l
0.32
314
2874
106
844
1.29
1.62
1.9
2.1
139.66
136.36
ug/g
0.03
80
675
5
14
3.58
1.61
1.2
1.1
—
—
—
0
0
140
1154
1.25
1.61
3.2
2.5
19.78
22.30
%
1.48
124
983
189
1609
1.21
1.60
1.2
1.2
0.96
1.49
u/ml
0.94
44
417
303
2693
1.18
1.60
3.9
3.8
10.30
9.50
mg/mmol
0.11
185
1700
60
440
1.39
1.60
2.5
2.4
—
—
—
0
0
297
2637
1.18
1.59
2.5
2.4
—
—
—
0
0
126
1028
1.26
1.59
2.6
2.4
1.89
1.81
%
0.37
110
913
287
2542
1.18
1.58
3.1
3.2
306.83
274.65
mg/l
0.05
179
1626
21
122
1.74
1.55
1.2
1.4
—
—
—
0
0
94
742
1.29
1.54
9.5
6.9
10.35
10.36
mmol/l
0.01
87
706
14
71
1.99
1.54
1.1
1.3
35.24
30.60
%
—
7
46
113
914
1.27
1.53
1.7
1.7
—
—
—
0
0
38
258
1.49
1.52
1.7
1.6
—
—
—
0
0
113
917
1.26
1.50
6.9
7.4
95.09
95.39
%
0.26
105
885
9
37
2.44
1.48
1.1
1.4
1.55
1.62
g/l
—
9
37
429
3941
1.15
1.45
4.4
3.9
0.00
0.00
estimate
0.75
82
790
20
117
1.72
1.45
1.6
1.9
33.25
32.44
pg
0.49
20
117
368
3349
1.16
1.41
3.3
2.7
128.38
137.57
ug/l
0.37
337
3056
285
2546
1.17
1.40
3.3
3.1
32.81
31.97
u/l
0.11
269
2417
32
214
1.51
1.39
2.7
2.4
94.49
84.68
ug/min
0.09
21
124
41
289
1.44
1.38
2.9
3.9
91.88
77.77
mg/l
0.13
35
234
41
289
1.44
1.38
2.9
3.9
36.74
45.89
mg/l
0.36
35
236
81
638
1.29
1.37
1.6
2.7
—
—
—
0
0
94
755
1.27
1.37
2.0
3.0
65.72
66.55
g/l
0.52
89
686
15
82
1.84
1.36
1.5
1.2
—
—
—
0
0
271
2417
1.17
1.36
5.1
4.3
—
—
—
0
0
40
282
1.44
1.35
3.0
3.9
1.40
1.89
ratio
—
6
25
117
966
1.24
1.35
1.7
1.4
—
—
—
0
0
103
839
1.25
1.34
6.9
7.8
119.18
120.39
g/l
0.25
98
819
115
951
1.24
1.31
3.2
4.1
11.50
28.17
ug/l
0.94
96
793
8
34
2.36
1.29
1.9
1.3
—
—
—
0
0
5
18
2.79
1.28
5.0
6.2
—
—
—
0
0
45
328
1.39
1.28
1.5
2.5
8.59
10.45
g/l
2.75
40
291
391
3594
1.14
1.28
2.2
2.1
94.33
94.29
pmol/l
0.01
214
1833
640
6081
1.14
1.26
4.5
4.0
15.07
14.92
pmol/l
0.78
570
5473
30
203
1.49
1.26
1.6
1.3
—
—
—
0
0
201
1761
1.18
1.26
5.1
4.3
1.02
1.02
kg/l
0.14
24
255
16
92
1.75
1.25
1.4
1.3
—
—
—
0
0
28
187
1.51
1.25
2.2
2.2
132.17
128.75
g/l
0.25
23
135
21
131
1.62
1.24
1.8
2.1
—
—
—
0
0
33
229
1.46
1.23
5.0
5.0
—
—
—
0
0
227
2013
1.16
1.22
2.2
2.3
—
—
—
0
0
6
26
2.32
1.19
1.0
1.8
18.67
15.59
pmol/l
—
6
19
16
94
1.71
1.18
1.3
1.2
—
—
nmol/l
—
0
0
136
1161
1.20
1.15
1.2
1.2
—
—
—
0
0
630
6001
1.13
1.13
4.6
4.2
14.38
13.45
mm/h
0.68
582
5505
31
217
1.44
1.12
2.6
4.1
—
—
—
0
0
243
2180
1.15
1.12
2.7
2.7
12645.75
7207.71
umol/l
0.48
214
1870
439
4094
1.13
1.12
19.4
16.6
1.29
1.29
inr
0.04
135
1154
70
559
1.27
1.10
4.3
3.7
7.42
7.41
ph
0.20
11
69
342
3143
1.13
1.10
4.3
3.6
5.69
5.76
ph
0.12
16
187
209
1859
1.16
1.08
4.4
3.9
—
—
—
0
0
17
105
1.63
1.06
1.2
1.1
—
21.34
—
0
5
17
105
1.63
1.06
1.4
1.2
0.69
0.63
nmol/l
0.21
17
96
20
129
1.56
1.06
1.3
1.2
9.53
10.87
u/l
0.21
13
102
75
608
1.25
1.05
4.8
4.1
0.27
0.57
%
0.25
22
179
16
98
1.64
1.03
1.4
1.2
—
—
—
0
0
5
22
2.28
1.03
1.0
1.3
—
—
—
0
0
7
34
2.07
1.03
3.1
2.7
1482.14
1246.09
u/ml
—
7
34
91
757
1.22
1.02
2.1
2.4
33.26
35.72
u/l
0.26
77
640
815
7915
1.15
1.02
19.3
15.5
26.16
25.14
mg/l
0.35
678
6385
10
53
1.90
1.01
1.5
1.4
1.20
1.17
promille
—
5
42
15
91
1.66
1.01
1.8
2.4
0.83
1.59
g/24h
—
6
44
14
84
1.68
0.98
1.1
1.4
—
—
—
0
0
360
3342
1.12
0.97
4.6
3.9
41.14
48.22
ng/l
0.26
261
2465
9
50
1.81
0.96
1.2
1.5
—
—
—
0
0
151
1324
1.17
0.96
1.3
1.3
28.35
34.08
iu/ml
0.43
59
424
6
117
0.51
0.94
3.8
1.3
—
—
—
0
0
90
755
1.21
0.94
2.8
3.0
288.57
228.42
ng/l
0.40
77
693
22
150
1.48
0.93
1.5
1.2
—
—
—
0
0
82
683
1.22
0.92
4.6
4.0
1.39
1.00
%
0.45
27
253
6
28
2.15
0.91
1.0
1.2
—
—
—
0
0
22
151
1.47
0.91
1.5
1.6
—
—
—
0
0
192
1722
1.14
0.90
3.4
3.2
2.46
2.46
mmol/l
0.11
173
1519
6
29
2.08
0.89
1.2
1.5
—
—
—
0
0
25
178
1.41
0.87
3.6
3.8
—
—
—
0
0
46
362
1.28
0.85
4.6
4.8
—
—
—
0
0
12
72
1.67
0.85
1.2
1.1
—
—
—
0
0
15
96
1.57
0.84
1.5
1.3
—
—
—
0
0
52
419
1.25
0.81
4.4
3.8
—
—
—
0
0
26
190
1.38
0.79
1.2
1.2
—
—
—
0
0
76
640
1.20
0.79
4.7
4.1
0.18
0.11
%
0.25
22
211
0
24
0.00
0.79
0.0
1.0
—
0.73
—
0
5
0
24
0.00
0.79
0.0
1.0
—
0.31
—
0
8
15
98
1.54
0.78
1.5
1.2
—
—
—
0
0
237
2174
1.12
0.78
5.0
4.2
0.00
0.00
estimate
0.50
66
706
7
124
0.56
0.78
1.3
1.1
—
—
—
0
0
5
99
0.50
0.78
3.6
1.2
—
—
—
0
0
0
27
0.00
0.77
0.0
2.6
—
—
—
0
0
11
67
1.65
0.75
1.1
1.2
2.24
1.55
nmol/l
0.95
11
59
5
24
2.09
0.74
1.0
1.2
232.60
195.82
iu/ml
—
5
24
25
184
1.37
0.74
4.1
4.6
3.85
2.76
mmol/l
0.51
14
132
21
150
1.41
0.73
1.3
1.5
—
—
—
0
0
73
618
1.20
0.73
4.6
3.9
1.17
0.58
%
1.02
23
213
697
6758
1.10
0.72
22.5
18.4
14.60
15.22
%
2.94
686
6641
30
230
1.31
0.70
1.3
1.5
0.25
0.24
g/l
0.37
30
220
9
146
0.61
0.69
1.3
1.9
55.89
60.78
%
—
9
146
32
248
1.30
0.69
3.6
3.2
—
—
—
0
0
12
77
1.57
0.68
1.7
1.1
—
—
—
0
0
80
689
1.17
0.67
1.8
1.5
—
—
—
0
0
11
70
1.58
0.65
1.1
1.0
0.20
3.23
u/ml
—
6
23
31
242
1.29
0.65
1.3
1.5
1.21
1.18
g/l
0.28
31
232
8
129
0.62
0.64
3.1
1.3
—
—
—
0
0
8
129
0.62
0.64
3.1
1.3
—
—
—
0
0
64
544
1.19
0.63
5.8
9.0
94.24
93.94
%
0.28
64
539
66
565
1.18
0.61
3.1
3.0
—
—
—
0
0
19
139
1.37
0.60
1.7
1.5
—
—
—
0
0
23
300
0.76
0.60
3.0
3.1
0.52
0.28
g/l
0.55
11
117
750
7325
1.09
0.59
5.4
4.8
1.95
2.13
mu/l
0.54
685
6619
0
22
0.00
0.59
0.0
1.7
—
31.72
—
0
16
16
114
1.41
0.59
2.1
1.8
87.88
89.74
%
0.45
16
114
28
219
1.29
0.59
2.2
3.1
0.80
0.84
nmol/l
0.19
19
175
69
596
1.17
0.58
1.4
1.4
—
—
—
0
0
52
438
1.20
0.58
1.3
1.3
—
—
—
0
0
7
114
0.61
0.58
1.0
1.1
—
—
—
0
0
11
73
1.51
0.56
1.1
1.0
0.48
4.23
u/ml
—
5
28
26
203
1.29
0.56
1.5
1.7
—
—
—
0
0
44
367
1.21
0.55
1.3
1.2
—
—
—
0
0
19
142
1.34
0.54
4.3
2.6
—
—
—
0
0
225
2100
1.09
0.54
4.0
3.6
—
—
—
0
0
82
723
1.15
0.54
4.0
3.5
—
—
—
0
0
17
126
1.36
0.51
2.2
2.6
—
—
—
0
0
843
8293
1.10
0.51
21.4
18.2
139.70
139.66
mmol/l
0.19
824
8059
86
764
1.14
0.51
2.6
2.5
74.95
69.58
e9/l
0.84
69
597
845
8314
1.10
0.51
21.9
18.3
3.97
3.98
mmol/l
1.18
825
8067
20
154
1.30
0.48
5.8
3.6
56.00
58.94
%
0.59
20
154
20
154
1.30
0.48
2.9
2.9
—
—
—
0
0
81
722
1.13
0.47
2.2
2.1
355.45
375.37
nmol/l
0.34
71
658
7
48
1.46
0.47
1.6
1.8
—
—
—
0
0
50
431
1.17
0.46
4.7
3.9
—
—
—
0
0
8
120
0.66
0.45
1.1
1.1
—
—
—
0
0
19
147
1.30
0.45
4.9
3.3
4.01
4.43
e9/l
0.34
19
147
10
69
1.45
0.44
1.8
1.2
—
—
—
0
0
49
424
1.16
0.43
1.4
1.3
—
—
—
0
0
9
127
0.71
0.43
2.9
1.3
—
—
—
0
0
9
128
0.70
0.43
2.9
1.3
—
—
—
0
0
46
397
1.17
0.42
3.7
3.6
25.17
24.14
mmol/l
1.37
46
388
31
258
1.21
0.42
1.3
1.4
263.48
287.43
ug/g
0.33
21
159
189
2009
0.93
0.41
1.4
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
2.8
—
4204.44
—
0
18
14
106
1.33
0.39
1.6
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
2.2
—
2.93
—
0
6
11
80
1.38
0.38
1.0
1.1
—
—
—
0
0
88
801
1.11
0.38
1.7
1.5
—
—
—
0
0
18
144
1.25
0.35
1.1
1.4
—
—
—
0
0
6
43
1.40
0.35
1.2
1.2
120.00
146.40
nmol/l
—
6
43
87
797
1.10
0.34
1.9
1.5
—
—
—
0
0
12
91
1.32
0.34
2.5
2.6
—
—
—
0
0
6
45
1.34
0.33
1.2
1.1
154.83
495.47
u/l
—
6
40
6
45
1.34
0.33
2.3
3.6
—
—
—
0
0
6
46
1.31
0.33
7.8
2.2
9.33
9.90
mmol/l
—
6
46
80
732
1.10
0.33
4.7
3.7
1.21
1.23
mmol/l
1.38
75
633
32
370
0.86
0.32
1.6
1.5
—
—
—
0
0
790
7796
1.06
0.32
5.3
4.8
6.16
6.00
mmol/l
2.14
710
7045
208
2180
0.94
0.31
1.5
1.6
1.38
1.37
mmol/l
0.07
170
1800
223
2131
1.06
0.31
1.6
1.6
20.94
20.70
nmol/l
0.07
191
1795
29
249
1.17
0.31
1.2
1.2
—
—
—
0
0
20
166
1.21
0.30
1.1
1.2
—
—
—
0
0
51
460
1.11
0.28
1.3
1.2
75.46
123.27
iu/ml
1.11
16
180
18
216
0.83
0.28
1.2
1.1
—
—
—
0
0
186
1774
1.06
0.28
1.6
1.6
1.34
1.25
mg/l
0.15
141
1381
848
8395
1.06
0.28
12.3
10.8
25.25
25.10
u/l
0.08
815
8067
8
62
1.29
0.28
1.1
1.1
—
—
—
0
0
178
1866
0.94
0.27
1.7
1.7
460.96
15167870.64
pmol/l
1.33
153
1523
8
66
1.21
0.26
1.9
1.1
—
—
—
0
0
10
77
1.30
0.26
1.1
1.9
—
—
—
0
0
165
1573
1.06
0.26
2.9
3.1
0.77
0.80
ug/l
0.10
109
1078
227
2184
1.05
0.25
2.7
2.1
3.28
3.10
mg/l
0.46
201
1844
759
7501
1.05
0.25
7.2
6.1
40.74
40.31
mmol/mol
0.61
695
6890
11
87
1.27
0.24
1.1
1.1
—
—
—
0
0
11
87
1.27
0.24
1.1
1.1
—
—
—
0
0
12
97
1.24
0.23
1.3
1.3
345585.71
100697.00
e6/l
—
7
55
40
362
1.11
0.22
1.8
1.9
—
—
—
0
0
92
866
1.07
0.22
6.2
4.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
7.46
—
0
5
0
12
0.00
0.21
0.0
1.3
—
1.69
—
0
12
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.59
—
0
5
0
12
0.00
0.21
0.0
11.6
—
6.18
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
48
1.25
0.20
26.8
11.3
—
—
—
0
0
6
48
1.25
0.20
6.2
2.0
—
—
—
0
0
6
49
1.23
0.20
1.0
1.2
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
23
203
1.14
0.19
1.1
1.2
440.83
496.09
mg/l
0.74
23
192
6
52
1.15
0.19
2.5
2.4
518.67
494.06
min
—
6
34
280
2729
1.04
0.18
5.1
5.2
2.64
3.40
ug/l
0.62
245
2414
7
58
1.21
0.18
1.1
1.2
—
—
—
0
0
7
63
1.11
0.17
2.3
2.4
—
—
—
0
0
505
4976
1.03
0.17
3.3
3.1
59.65
51.78
u/l
0.69
467
4579
180
1744
1.04
0.16
1.8
1.8
1195.48
1182.10
nmol/l
0.06
138
1307
89
934
0.95
0.16
2.8
2.7
4.63
8.26
umol/l
6.57
77
811
54
508
1.07
0.14
2.3
2.2
10.11
12.35
nmol/l
1.54
49
451
30
275
1.09
0.14
10.2
6.1
1.40
1.36
mmol/l
0.10
25
245
8
99
0.81
0.13
1.4
1.2
62.73
47.40
mu/l
—
8
88
72
686
1.05
0.13
4.5
3.9
—
—
—
0
0
31
287
1.08
0.12
1.1
1.1
—
—
—
0
0
873
8688
1.03
0.12
28.0
22.8
248.31
247.20
e9/l
0.19
851
8440
48
453
1.06
0.12
10.0
9.3
—
—
—
0
0
746
7510
0.97
0.12
4.5
4.1
1.35
1.28
mmol/l
1.40
663
6799
873
8691
1.03
0.11
27.8
22.7
30.31
30.37
pg
0.48
860
8531
873
8691
1.03
0.11
27.8
22.7
91.31
91.44
fl
0.38
860
8534
873
8691
1.03
0.11
27.9
22.8
7.00
6.75
e9/l
0.80
846
8412
873
8692
1.03
0.11
27.9
22.8
4.41
4.43
e12/l
0.71
843
8414
46
485
0.95
0.11
1.6
1.4
—
—
—
0
0
822
8180
1.03
0.10
18.0
14.7
—
—
—
0
0
32
300
1.07
0.10
1.6
1.7
—
—
—
0
0
873
8695
1.03
0.10
28.2
22.9
132.87
133.68
g/l
0.86
861
8533
12
106
1.13
0.09
1.3
1.2
—
—
—
0
0
12
134
0.89
0.08
4.8
3.3
1.33
1.30
%
0.02
12
122
780
7763
1.02
0.08
4.9
4.6
1.44
1.48
mmol/l
2.05
705
7070
5
60
0.83
0.08
1.2
1.1
—
—
—
0
0
20
185
1.08
0.08
4.0
3.6
21.10
27.86
mg/l
0.38
14
115
5
64
0.78
0.08
1.4
2.1
5.38
3.08
ug/l
—
5
58
10
88
1.14
0.08
1.2
1.3
—
—
—
0
0
274
2704
1.02
0.08
3.8
3.0
1804.14
1572.14
ng/l
0.32
230
2326
7
80
0.87
0.07
2.4
1.4
—
—
—
0
0
8
91
0.88
0.06
1.9
2.5
—
—
—
0
0
8
94
0.85
0.06
1.0
1.1
1.59
1.52
g/l
—
8
86
9
102
0.88
0.06
1.0
1.1
—
—
—
0
0
25
264
0.95
0.06
9.5
11.5
—
—
—
0
0
50
517
0.97
0.06
1.2
1.3
—
—
—
0
0
871
8688
1.02
0.05
27.9
22.9
39.19
39.68
%
1.18
811
8049
45
465
0.97
0.05
1.3
1.3
—
—
—
0
0
257
2545
1.01
0.05
4.7
4.0
—
—
—
0
0
261
2587
1.01
0.04
3.3
3.1
—
—
—
0
0
38
367
1.04
0.04
2.8
2.7
—
—
—
0
0
14
130
1.08
0.04
1.1
1.2
—
—
—
0
0
22
209
1.05
0.04
1.1
1.2
—
1216.25
—
0
8
14
131
1.07
0.03
1.1
1.4
—
—
—
0
0
20
191
1.05
0.03
1.2
1.7
1.32
4.92
iu/l
—
6
54
128
1267
1.01
0.02
1.3
1.3
4.91
11.45
u/ml
1.31
49
472
13
138
0.94
0.02
1.8
1.7
—
—
—
0
0
21
218
0.96
0.02
2.9
2.5
—
—
—
0
0
801
8000
1.01
0.01
5.6
5.2
2.66
2.70
mmol/l
0.55
732
7291
20
193
1.04
0.01
1.1
1.1
—
92.50
—
0
16
22
213
1.03
0.01
1.1
1.1
—
—
—
0
0
89
896
0.99
0.00
1.2
1.3
—
—
—
0
0
55
554
0.99
0.00
1.3
1.2
—
—
—
0
0
18
182
0.99
0.00
2.0
2.5
—
—
—
0
0
36
359
1.00
0.00
1.9
1.4
—
—
—
0
0
17
169
1.01
0.00
1.2
1.2
—
—
—
0
0
52
517
1.01
0.00
3.2
3.0
4.83
6.84
e9/l
0.69
39
408
782
7819
1.00
0.00
5.0
4.7
4.57
4.62
mmol/l
0.69
710
7175
9
98
0.92
0.00
4.7
3.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
58
0.86
-0.00
1.4
1.7
11.14
10.69
%
—
5
58
8
83
0.96
-0.00
6.3
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
7
71
0.99
-0.00
1.6
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
—
—
0
0
5
59
0.85
-0.00
3.4
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.8
—
—
—
0
0
5
55
0.91
-0.00
1.6
1.6
—
—
—
0
0
5
54
0.93
-0.00
3.2
1.5
95.20
83.52
umol/l
—
5
54
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.3
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.0
—
0.38
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
55
0.91
-0.00
1.8
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_SALIVARY_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_SALIVARY_NOS 1.304 [1.12, 1.52] < 0.001
Birth year 0.995 [0.99, 1.0] 0.225

During the follow-up period (1.1.1998 — 31.12.2019), 403 out of 1694 females with CD2_BENIGN_SALIVARY_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_SALIVARY_NOS 1.63 [1.38, 1.93] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 407 out of 1374 males with CD2_BENIGN_SALIVARY_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_SALIVARY_NOS.

N-year risk Females Males
1 0.084% 0.371%
5 0.664% 1.865%
10 1.9% 4.564%
15 3.672% 8.531%
20 6.75% 14.404%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_SALIVARY_NOS – Benign neoplasm: other/unspecified salivary gland

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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