Postmenopausal osteoporosis with pathological fracture

OSTPOPATFRCTURE_POSTEMENO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M80.0
  • Cause of death: ICD-10 M80.0

2 out of 7 registries used, show all original rules.

2057

4. Check minimum number of events

None

2057

5. Include endpoints

None

2057

6. Filter based on genotype QC (FinnGen only)

2057

Control definitions (FinnGen only)

Control exclude
OSTEOPOROSIS_FRACTURE_FG

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M80
Name in latin
Osteoporosis postmenopausalis cum fractura pathologica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19351 19351 -
Only index persons 17522 17522 -
Unadjusted period prevalence (%)
Whole population 0.55 0.55 -
Only index persons 0.64 0.64 -
Median age at first event (years)
Whole population - 79.64 -
Only index persons - 79.50 -

-FinnGen-

Key figures

All Female Male
Number of individuals 2057 2057 -
Unadjusted period prevalence (%) 0.70 0.70 -
Median age at first event (years) 73.88 73.88 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1767
Matched controls
17668
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M05BX04
ATC
denosumab; parenteral
13.9
323.0
698
791
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
+∞
323.0
1767
115
M05BA04
ATC
alendronic acid; oral
7.0
263.4
821
1956
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.6
256.5
1436
6995
L95
ICPC
Osteoporosis
11.1
221.3
456
538
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
18.7
208.7
333
217
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.6
187.4
562
1171
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
12.6
177.6
336
323
M81.9
ICD-10 Finland
Osteoporosis, unspecified
7.9
175.2
445
724
318
Kela drug reimbursment
Teriparatide
77.2
165.6
187
27
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
15.5
158.6
271
204
H05AA02
ATC
teriparatide; parenteral
80.1
154.9
174
24
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.6
141.0
1048
5069
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.9
135.3
426
899
M05BA07
ATC
risedronic acid; oral
6.6
132.2
377
698
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.8
125.3
682
2487
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
6.1
117.1
354
699
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
6.7
108.8
302
529
M54.5
ICD-10 Finland
Low back pain
3.1
107.8
865
4123
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
12.3
97.7
183
164
N02AA05
ATC
oxycodone; systemic
3.4
90.2
550
2088
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
75.7
573
2475
N02AX02
ATC
tramadol; systemic, rectal
2.5
73.0
972
5803
X59
ICD-10 Finland
Exposure to unspecified factor
3.1
72.8
492
1961
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
7.5
70.7
175
254
M80
ICD-10 Finland
Osteoporosis with pathological fracture
11.1
64.6
126
121
M05BB03
ATC
alendronic acid and colecalciferol; oral
5.2
64.6
216
462
L03
ICPC
Low back symptom/complaint
2.6
64.4
642
3206
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
171.2
63.4
66
*
L76
ICPC
Fracture: other
6.0
63.1
185
338
M05BA06
ATC
ibandronic acid; systemic
5.5
58.4
183
362
M05BX03
ATC
strontium ranelate; oral
11.3
53.6
103
96
N03AX12
ATC
gabapentin; oral
2.7
52.4
436
1922
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
52.2
981
6472
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
9.6
51.4
108
119
L28
ICPC
Limited function/disability (L)
2.4
51.1
543
2735
A28
ICPC
Limited function/disability NOS
2.4
48.2
543
2801
N03AX16
ATC
pregabalin; oral
2.3
47.5
603
3291
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
25.3
47.0
66
27
N02BE01
ATC
paracetamol; systemic, rectal
3.6
46.1
1668
14573
S52.5
ICD-10 Finland
Fracture of lower end of radius
2.6
43.0
377
1690
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.1
41.7
256
919
S72.0
ICD-10 Finland
Fracture of neck of femur
3.5
40.9
209
655
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.0
40.8
262
969
L02
ICPC
Back symptom/complaint
3.0
40.6
257
942
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
39.6
406
1968
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.0
39.4
882
5964
SPAT1254
SPAT
Administration of medicine
2.3
39.1
438
2217
SPAT1229
SPAT
Assessment of need for aid
2.7
38.1
301
1263
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
6.1
38.0
108
188
W19
ICD-10 Finland
Unspecified fall
2.8
37.9
278
1114
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
37.9
465
2449
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.9
37.9
888
6076
X58
ICD-10 Finland
Exposure to other specified factors
2.7
37.3
282
1152
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
37.2
668
4126
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.6
36.2
293
1245
A06AD11
ATC
lactulose; oral
2.2
35.0
450
2408
AA1AD
NOMESCO Finland
CT of head and brain
2.0
34.6
598
3614
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
33.8
472
2613
C03CA01
ATC
furosemide; systemic
1.9
33.5
820
5609
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.9
33.5
221
826
A02BC02
ATC
pantoprazole; systemic
1.9
33.1
1288
10308
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
32.6
684
4417
M48.0
ICD-10 Finland
Spinal stenosis
2.2
31.6
363
1833
M80.5
ICD-10 Finland
Idiopathic osteoporosis with pathological fracture
23.0
31.4
45
20
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
30.6
246
1036
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.8
30.5
208
791
H02AB06
ATC
prednisolone; systemic
1.8
30.2
905
6535
NF1AA
NOMESCO Finland
Hip X-ray examination
2.4
29.9
288
1332
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.9
29.9
197
734
5BA08
NOMESCO Finland
NA
13.8
29.6
51
38
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
29.6
442
2494
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.4
28.6
266
1209
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
28.1
507
3065
S22.3
ICD-10 Finland
Fracture of rib
3.2
28.0
157
523
NA2AD
NOMESCO Finland
Thoracic spine CT examination
12.9
27.7
49
39
S72.1
ICD-10 Finland
Pertrochanteric fracture
3.8
25.7
114
317
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.5
25.6
126
381
M54.6
ICD-10 Finland
Pain in thoracic spine
2.9
25.5
162
589
S32.7
ICD-10 Finland
Multiple fractures of lumbar spine and pelvis
7.3
25.5
62
88
M54
ICD-10 Finland
Dorsalgia
2.3
24.6
248
1167
ZX120
NOMESCO Finland
Intravenous
2.5
24.3
210
913
B01AB05
ATC
enoxaparin; parenteral
1.7
23.9
675
4668
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.3
23.9
234
1087
R03BB04
ATC
tiotropium bromide; inhalant
2.5
23.8
202
871
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
23.1
281
1438
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.5
22.8
68
127
L84
ICPC
Back syndrome without radiat pain
3.2
22.6
127
423
NF3AA
NOMESCO Finland
Femur X-ray examination
4.4
22.5
83
195
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.8
22.3
155
595
L17
ICPC
Foot/toe symptom/complaint
1.7
22.0
536
3522
M81.8
ICD-10 Finland
Other osteoporosis
7.5
22.0
52
71
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
8.2
21.5
48
60
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.7
21.5
158
628
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.7
21.5
157
621
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
21.4
273
1422
R53
ICD-10 Finland
Malaise and fatigue
1.8
21.3
480
3074
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.8
21.3
93
256
WX704
NOMESCO Finland
Intubation
2.7
21.3
150
582
SPAT1216
SPAT
Assessment of functional ability
1.8
21.1
431
2673
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
20.9
194
872
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
20.9
249
1258
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
20.9
676
4811
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
20.9
339
1942
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
20.8
345
1989
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
20.7
284
1525
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.8
20.6
142
543
L04AX01
ATC
azathioprine; systemic
3.4
20.6
104
322
J01MA02
ATC
ciprofloxacin; systemic
1.6
20.6
735
5364
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
3.7
20.3
90
251
L86
ICPC
Back syndrome with radiating pain
2.7
20.2
149
592
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.1
19.8
254
1325
SPAT1301
SPAT
No procedures
1.6
19.4
680
4919
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
19.4
483
3175
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
3.7
19.3
85
236
327
Kela drug reimbursment
strontium ranelate
26.3
19.1
26
10
R60.0
ICD-10 Finland
Localized oedema
1.9
18.8
291
1631
N06AX21
ATC
duloxetine; oral
2.1
18.7
230
1176
NK6PA
NOMESCO Finland
Measurement of bone density from one location with X-ray
13.6
18.7
32
24
SPAT1263
SPAT
Sampling
1.6
18.6
807
6138
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
3.5
18.5
87
255
M81.5
ICD-10 Finland
Idiopathic osteoporosis
5.6
18.5
54
99
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
18.3
410
2604
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
18.0
632
4547
H02AB09
ATC
hydrocortisone; systemic
4.6
17.9
63
142
M05BA01
ATC
etidronic acid; systemic
5.7
17.9
51
91
A01
ICPC
Pain general/multiple sites
2.1
17.7
216
1100
J01FF01
ATC
clindamycin; systemic
1.7
17.7
465
3093
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.2
17.6
181
855
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
17.5
377
2361
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.4
17.4
87
268
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
17.3
306
1795
347
Kela drug reimbursment
denosumab
24.3
17.3
24
10
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
17.3
398
2542
M79.6
ICD-10 Finland
Pain in limb
1.6
17.2
700
5212
WX212
NOMESCO Finland
Femoral plexus blockade
3.5
17.1
81
239
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
17.0
226
1192
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.6
17.0
128
516
K59.09
ICD-10 Finland
Constipation, unspecified
2.4
17.0
156
698
N30.0
ICD-10 Finland
Acute cystitis
1.7
17.0
401
2580
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.4
16.7
82
249
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
6.3
16.7
44
71
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.7
16.7
121
474
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.9
16.6
102
363
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
16.5
180
873
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
16.5
350
2179
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
16.5
368
2324
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.7
16.5
117
456
WX725
NOMESCO Finland
Noninvasive ventilation
2.9
16.4
102
366
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
16.2
253
1417
L29
ICPC
Musculoskeletal sympt/complt other
2.2
16.0
179
879
N06AX11
ATC
mirtazapine; oral
1.6
15.9
623
4567
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
15.9
281
1646
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
15.9
178
873
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.6
15.9
117
465
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.3
15.8
158
734
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
3.1
15.8
87
289
L75
ICPC
Fracture: femur
3.9
15.7
64
167
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
15.5
177
877
S32.8
ICD-10 Finland
Fracture of other and unspecified parts of lumbar spine and pelvis
4.5
15.4
54
122
S97
ICPC
Chronic ulcer skin
2.4
15.3
135
591
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.8
15.2
65
177
M48.5
ICD-10 Finland
Collapsed vertebra, not elsewhere classified
8.8
15.2
32
37
R11
ICD-10 Finland
Nausea and vomiting
2.0
15.2
204
1078
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
15.0
361
2323
J01EA01
ATC
trimethoprim; systemic
1.5
14.9
671
5064
S01.0
ICD-10 Finland
Open wound of scalp
2.3
14.8
149
694
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
14.8
224
1240
ZZH40
NOMESCO Finland
Substitute of bone
5.2
14.7
45
88
A29
ICPC
General symptom/complaint other
1.8
14.7
253
1464
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
14.7
219
1204
P01BA02
ATC
hydroxychloroquine; oral
2.0
14.5
197
1045
M03BX02
ATC
tizanidine; oral
1.5
14.5
962
7882
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.2
14.5
76
244
-50
ICPC
Medication/prescr/renewal
2.6
14.4
104
408
H02AB07
ATC
prednisone; oral
1.8
14.4
297
1824
ZXA00
NOMESCO Finland
Right side
1.5
14.1
583
4304
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.8
14.1
90
328
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.1
13.9
75
246
J01DB01
ATC
cefalexin; oral
1.6
13.9
1371
12179
U04
ICPC
Incontinence urine
2.2
13.8
140
654
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
13.8
326
2084
A02BC05
ATC
esomeprazole; systemic
1.5
13.8
758
5941
A02BC01
ATC
omeprazole; systemic
1.5
13.8
570
4199
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
20.2
13.8
20
10
L05
ICPC
Flank/axilla symptom/complaint
2.3
13.8
127
568
SPAT1234
SPAT
Support of social functional capacity
2.1
13.8
156
769
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.1
13.7
163
821
L13
ICPC
Hip symptom/complaint
1.6
13.7
386
2588
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.0
13.7
183
965
SPAT1255
SPAT
Intravenous administration of medicine
2.2
13.7
140
660
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
13.5
154
761
S70.0
ICD-10 Finland
Contusion of hip
2.5
13.4
111
470
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.5
13.4
106
440
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
13.4
304
1920
M54.8
ICD-10 Finland
Other dorsalgia
2.7
13.3
91
347
M81.4
ICD-10 Finland
Drug-induced osteoporosis
8.2
13.3
29
36
A04
ICPC
Weakness/tiredness general
1.7
13.2
305
1934
SPAT1260
SPAT
Consultation of another employee
1.6
13.2
361
2402
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.0
13.2
75
254
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.3
13.1
66
206
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
5.3
13.0
39
75
N06AA09
ATC
amitriptyline; systemic
1.8
13.0
251
1505
J01MA12
ATC
levofloxacin; systemic
1.7
13.0
312
1997
S32.5
ICD-10 Finland
Fracture of pubis
4.2
13.0
49
120
S20.2
ICD-10 Finland
Contusion of thorax
2.6
13.0
96
384
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.1
12.9
145
711
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.7
12.8
89
344
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
12.8
151
758
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
12.7
864
7031
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.4
12.6
110
481
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
12.6
119
539
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.1
12.5
148
744
UJF32
NOMESCO Finland
Coloscopy
1.5
12.4
513
3765
SPAT1210
SPAT
Application of cast or individual aid
2.4
12.3
105
455
R03AC02
ATC
salbutamol; inhalant
1.4
12.3
870
7119
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.1
12.3
135
659
NA7LT
NOMESCO Finland
Percutaneous vertebroplasty
37.8
12.2
15
*
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.8
12.1
221
1302
Y94.0
ICD-10 Finland
Accident at home
3.2
12.1
63
203
ND1BA
NOMESCO Finland
Wrist extensive X-ray examination
2.9
12.0
74
264
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.6
12.0
30
46
S22.1
ICD-10 Finland
Multiple fractures of thoracic spine
13.5
11.9
20
15
NAK40
NOMESCO Finland
Vertebroplasty
47.0
11.9
14
*
M01AH02
ATC
rofecoxib; oral
1.6
11.8
313
2058
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
11.8
96
405
SPAT1172
SPAT
Guidance concerning hydration
2.5
11.8
90
367
M40.1
ICD-10 Finland
Other secondary kyphosis
11.8
11.8
21
18
B01AA03
ATC
warfarin; systemic
1.5
11.8
436
3110
E21.0
ICD-10 Finland
Primary hyperparathyroidism
3.3
11.7
59
185
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.6
11.7
84
330
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.1
11.6
130
639
M80.1
ICD-10 Finland
Postoophorectomy osteoporosis with pathological fracture
19.1
11.6
17
9
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.4
11.6
96
407
SPAT1053
SPAT
Memory test
1.6
11.5
384
2673
L88
ICPC
Rheumatoid/seropositive arthritis
2.4
11.5
96
409
S82.0
ICD-10 Finland
Fracture of patella
3.3
11.5
57
177
S72.2
ICD-10 Finland
Subtrochanteric fracture
4.3
11.4
41
97
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
11.3
149
780
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
11.3
569
4330
S06.0
ICD-10 Finland
Concussion
1.8
11.3
194
1120
S18
ICPC
Laceration/cut
1.4
11.3
749
6021
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
11.3
100
440
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
10.6
11.3
21
20
K59.0
ICD-10 Finland
Constipation
2.0
11.2
138
705
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
11.2
184
1045
NBJ62
NOMESCO Finland
Internal fixation of fracture of shoulder or upper arm using plate and screws, humerus
3.6
11.2
49
138
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
11.2
742
5957
N05CF01
ATC
zopiclone; oral
1.4
11.2
679
5364
S52.6
ICD-10 Finland
Fracture of lower end of both ulna and radius
2.8
11.2
70
255
WX320
NOMESCO Finland
Spinalanesthesy
1.5
11.2
425
3050
N06AB04
ATC
citalopram; systemic
1.5
11.1
413
2943
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.5
11.0
85
350
M01AH05
ATC
etoricoxib; oral
1.4
10.9
922
7724
N05BA01
ATC
diazepam; systemic, rectal
1.6
10.9
274
1771
Z04.3
ICD-10 Finland
Examination and observation following other accident
3.4
10.9
52
157
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
10.9
178
1013
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.0
10.9
60
202
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
10.8
157
855
A46
ICD-10 Finland
Erysipelas
1.7
10.8
262
1681
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.0
10.7
61
207
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
10.7
194
1141
ZXA05
NOMESCO Finland
Left side
1.5
10.6
534
4056
R50.9
ICD-10 Finland
Fever, unspecified
1.7
10.6
208
1252
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.1
10.6
123
615
R96
ICPC
Asthma
1.8
10.6
184
1067
G20
ICD-10 Finland
Parkinson disease
2.6
10.5
77
305
J46
ICD-10 Finland
Status asthmaticus
2.6
10.5
75
296
C03DA01
ATC
spironolactone; oral
1.7
10.5
242
1530
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
10.4
721
5809
R60.9
ICD-10 Finland
Oedema, unspecified
2.1
10.4
112
541
NC2AA
NOMESCO Finland
Forearm X-ray examination
4.3
10.4
37
87
S52.0
ICD-10 Finland
Fracture of upper end of ulna
3.1
10.4
55
180
J01DA01
ATC
[U] cefalexin; systemic
1.4
10.3
1049
9043
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.9
10.3
60
209
N30.9
ICD-10 Finland
Cystitis, unspecified
1.9
10.3
158
878
A02BA02
ATC
ranitidine; systemic
1.5
10.2
419
3049
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
10.2
96
438
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.3
10.1
91
406
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
10.1
594
4637
N87
ICPC
Parkinsonism
3.6
10.1
44
124
WX702
NOMESCO Finland
Supraglottic ventilation device
2.2
10.1
96
440
NCJ62
NOMESCO Finland
Internal fixation of fracture of forearm using plate
3.0
10.1
58
200
K07
ICPC
Swollen ankles/oedema
2.0
10.0
127
656
R95
ICPC
Chron obstructive pulmonary disease
3.2
10.0
50
157
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
3.9
10.0
40
105
R06.0
ICD-10 Finland
Dyspnoea
1.4
10.0
499
3776
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
10.0
298
2015
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
9.9
202
1229
R03DC03
ATC
montelukast; oral
1.6
9.9
264
1734
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
9.9
88
389
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
3.1
9.8
53
176
E83.50
ICD-10 Finland
Hypercalcemia
3.7
9.8
42
117
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
9.8
184
1091
R52.9
ICD-10 Finland
Pain, unspecified
1.8
9.8
163
929
L12
ICPC
Hand/finger symptom/complaint
1.6
9.8
246
1592
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.4
9.7
82
353
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.8
9.7
168
971
UKC02
NOMESCO Finland
Cystoscopy
1.7
9.7
227
1437
L72
ICPC
Fracture: radius/ulna
2.6
9.6
66
255
C07AB07
ATC
bisoprolol; oral
1.4
9.6
947
8070
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
9.6
73
300
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
9.5
254
1664
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
9.5
521
4003
R4110
NOMESCO Finland
Physiotherapy
1.4
9.5
473
3571
R03AC12
ATC
salmeterol; inhalant
2.1
9.5
101
487
R03BA05
ATC
fluticasone; inhalant
1.5
9.5
312
2158
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
9.4
78
335
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
9.4
107
529
N05AH04
ATC
quetiapine; oral
1.6
9.4
238
1542
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.2
9.4
95
446
R03BB01
ATC
ipratropium bromide; inhalant
2.2
9.4
91
422
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
9.4
107
532
R06AE07
ATC
cetirizine; oral
1.4
9.4
726
5938
NA7AD
NOMESCO Finland
Spine CT
21.8
9.3
13
6
R33
ICD-10 Finland
Retention of urine
2.3
9.3
85
381
S32.1
ICD-10 Finland
Fracture of sacrum
4.4
9.3
32
73
J01CA08
ATC
pivmecillinam; oral
1.4
9.3
1039
9015
E87.6
ICD-10 Finland
Hypokalaemia
2.3
9.3
87
394
I95.1
ICD-10 Finland
Orthostatic hypotension
2.3
9.3
85
383
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.6
9.3
67
267
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
2.1
9.3
106
525
WX872
NOMESCO Finland
Intensive care
2.4
9.2
77
332
R07.3
ICD-10 Finland
Other chest pain
1.7
9.2
189
1152
NB6AA
NOMESCO Finland
Humerus X-ray examination
2.6
9.2
63
244
E0000UV
ATC
NA
1.4
9.2
669
5409
A08
ICPC
Swelling
2.0
9.1
112
573
R51.80
ICD-10 Finland
Headache
1.6
9.1
229
1478
S72.3
ICD-10 Finland
Fracture of shaft of femur
3.9
9.1
36
94
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.3
9.1
84
380
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.2
9.1
91
426
L11
ICPC
Wrist symptom/complaint
1.8
9.1
156
901
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.3
9.1
83
371
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
2.1
9.1
96
461
W17
ICD-10 Finland
Other fall from one level to another
2.8
9.1
57
208
N18
ICPC
Paralysis/weakness
3.0
9.0
50
170
L04AA06
ATC
mycophenolic acid; systemic
4.4
9.0
31
71
N05BA04
ATC
oxazepam; oral
1.4
9.0
472
3594
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
9.0
272
1841
R02
ICPC
Shortness of breath/dyspnoea
1.6
9.0
241
1582
WX402
NOMESCO Finland
General anaesthesia
1.6
9.0
235
1536
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
2.5
9.0
66
267
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
2.2
8.9
87
402
NFJ50
NOMESCO Finland
Internal fixation of fracture of neck of femur with nail or screw
5.3
8.9
26
50
SPAT1310
SPAT
Counselling related to known health issue
1.4
8.9
553
4343
NFJ60
NOMESCO Finland
Internal fixation of fracture of other parts of femur with intramedullary nail
5.5
8.9
25
46
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.2
8.8
85
393
A01AB09
ATC
miconazole; local oral
1.6
8.8
221
1425
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.6
8.8
230
1499
R03AC13
ATC
formoterol; inhalant
2.1
8.8
101
505
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
14.1
8.7
14
10
W10
ICD-10 Finland
Fall on and from stairs and steps
2.0
8.7
104
527
L04AA13
ATC
leflunomide; oral
2.7
8.7
59
227
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
8.6
77
342
S92.3
ICD-10 Finland
Fracture of metatarsal bone
2.5
8.6
65
264
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
8.6
131
725
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.3
8.6
74
323
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
8.5
534
4192
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.1
8.5
94
459
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
8.5
123
669
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.0
8.5
113
596
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
8.5
928
7973
SPAT1211
SPAT
Application of soft bandage
1.7
8.5
179
1102
WX002
NOMESCO Finland
Sedation and analgesia
1.5
8.4
373
2741
T08
ICPC
Weight loss
3.4
8.4
39
117
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.3
8.4
41
128
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.4
8.4
38
112
NDJ62
NOMESCO Finland
Internal fixation of fracture of wrist or hand using plate and screws, schaphoid
3.5
8.4
37
107
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
7.9
8.4
18
23
Y94.8
ICD-10 Finland
Other leisure activity accident
2.8
8.3
53
196
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
8.3
152
894
NAJ32
NOMESCO Finland
Posterior reduction of fractrue of lumbar spine
10.8
8.3
15
14
R03BA01
ATC
beclometasone; inhalant
1.5
8.3
267
1835
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.4
8.3
70
304
SPAT1167
SPAT
Insertion of urinary catheter
2.3
8.3
73
324
D10
ICPC
Vomiting
2.6
8.3
60
239
J45.8
ICD-10 Finland
Mixed asthma
2.6
8.3
60
240
SPAT1325
SPAT
Vaccination
1.4
8.2
661
5401
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
8.2
211
1370
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
2.4
8.2
66
277
A02BC03
ATC
lansoprazole; oral
1.4
8.2
577
4610
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
8.2
392
2925
M01CB01
ATC
sodium aurothiomalate; parenteral
3.0
8.2
45
153
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
8.2
203
1308
ZZH31
NOMESCO Finland
Bone allograft, small pieces
4.1
8.2
30
74
NCJ64
NOMESCO Finland
Other internal fixation of fracture of forearm
4.0
8.2
31
79
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.1
8.1
94
471
Y96.9
ICD-10 Finland
Unspecified type of accident
3.4
8.1
38
115
M84.1
ICD-10 Finland
Nonunion of fracture [pseudarthrosis]
5.4
8.1
23
43
G56.2
ICD-10 Finland
Lesion of ulnar nerve
2.9
8.1
47
164
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.4
8.1
66
282
7330A
ICD-9 Finland
Other disorders of bone and cartilage, Osteoporosis[OSTEOPOROSIS CENTRALIS]
17.2
8.1
12
7
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
2.8
8.1
48
172
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.0
877
7507
N29
ICPC
Neurological sympt/complt other
2.9
8.0
47
166
J01FA06
ATC
roxithromycin; oral
1.3
8.0
702
5809
NC1BA
NOMESCO Finland
Elbow extensive X-ray examination
5.6
8.0
22
40
S42.4
ICD-10 Finland
Fracture of lower end of humerus
3.5
8.0
35
101
S21
ICPC
Skin texture symptom/complaint
1.6
8.0
220
1454
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.7
7.9
52
198
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.9
297
2110
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
13.1
7.9
13
10
H02AB04
ATC
methylprednisolone; systemic
1.5
7.9
272
1898
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
7.9
262
1811
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
2.7
7.9
52
199
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
7.9
345
2528
M41.8
ICD-10 Finland
Other forms of scoliosis
5.4
7.8
22
41
N04BD02
ATC
rasagiline; oral
4.7
7.8
25
54
S22.4
ICD-10 Finland
Multiple fractures of ribs
3.2
7.8
38
119
L73
ICPC
Fracture: tibia/fibula
3.4
7.8
35
103
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
7.8
119
660
XG410
NOMESCO Finland
Flow-volume spirometry
2.2
7.8
72
328
K03.66
ICD-10 Finland
Tooth plaque
1.9
7.7
103
544
Y89.9
ICD-10 Finland
Sequelae of unspecified external cause
5.1
7.7
23
46
R03DA04
ATC
theophylline; systemic, rectal
1.9
7.7
107
575
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
6.4
7.7
19
30
JN4BD
NOMESCO Finland
Extensive body CT
1.6
7.6
194
1254
NDU10
NOMESCO Finland
Removal of external fixation device from wrist or hand
4.8
7.6
24
51
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
7.6
86
428
S82.1
ICD-10 Finland
Fracture of upper end of tibia
2.9
7.6
44
154
A50
ICPC
General and Unspecified, Medication/prescr/renewal
2.3
7.6
65
283
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
2.4
7.6
60
253
P20
ICPC
Memory disturbance
1.5
7.6
310
2240
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
7.6
302
2171
M05BA08
ATC
zoledronic acid; parenteral
8.9
7.5
15
17
J96.1
ICD-10 Finland
Chronic respiratory failure
3.0
7.5
43
148
A07AA02
ATC
nystatin; oral
1.7
7.5
155
946
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.5
7.5
57
236
WZA00
NOMESCO Finland
Short statement of of health and health related matters
2.0
7.5
93
478
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
2.9
7.5
43
149
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
7.5
152
927
R13
ICD-10 Finland
Dysphagia
1.8
7.5
124
709
L09
ICPC
Arm symptom/complaint
2.1
7.5
84
414
SPAT1245
SPAT
Provision of support and information to patient’s family members
1.9
7.5
113
627
WX204
NOMESCO Finland
Axillary plexus blockaced
2.5
7.5
56
230
WW200
NOMESCO Finland
Immunization
2.9
7.5
43
150
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.7
7.4
48
181
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
7.4
227
1538
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
7.4
292
2095
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
5.3
7.4
21
40
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
5.3
7.4
21
40
WZA90
NOMESCO Finland
Other doctors statement
1.4
7.4
334
2463
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
3.2
7.4
37
119
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.2
7.4
37
119
NFJ62
NOMESCO Finland
Internal fixation of fracture of other parts of femur with plate
3.6
7.4
31
87
A02BC04
ATC
rabeprazole; oral
1.7
7.4
144
868
H26.4
ICD-10 Finland
After-cataract
1.5
7.3
275
1949
T93.1
ICD-10 Finland
Sequelae of fracture of femur
8.4
7.3
15
18
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
1.9
7.3
106
580
S82.6
ICD-10 Finland
Fracture of lateral malleolus
1.9
7.3
110
611
J01AA02
ATC
doxycycline; systemic
1.4
7.3
1327
12177
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
2.8
7.3
45
166
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.0
7.3
40
137
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
4.9
7.3
22
45
R03BA02
ATC
budesonide; inhalant
1.5
7.3
293
2108
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
7.3
388
2948
S72.4
ICD-10 Finland
Fracture of lower end of femur
3.8
7.3
29
78
R03DC01
ATC
zafirlukast; oral
2.8
7.2
46
170
NF3AD
NOMESCO Finland
Femur CT
15.8
7.2
11
7
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.0
7.2
82
410
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.3
7.2
62
272
N05CD07
ATC
temazepam; oral
1.5
7.1
290
2089
NAK30
NOMESCO Finland
Osteotomy of spine
20.1
7.1
10
5
JN4AD
NOMESCO Finland
Body CT examination
1.8
7.1
126
735
NF3BA
NOMESCO Finland
Femur extensive X-ray examination
6.0
7.1
18
30
NFJ52
NOMESCO Finland
Internal fixation of fracture of upper femur with screws and sideplate
3.7
7.1
29
80
SPAT1125
SPAT
Stoma care and guidance
2.6
7.1
49
191
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.3
7.1
59
256
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.0
189
1243
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
3.5
7.0
30
86
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.3
7.0
33
102
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.8
7.0
27
71
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
7.0
132
790
M01AX17
ATC
nimesulide; oral
1.4
6.9
499
3985
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
6.9
91
483
M41.9
ICD-10 Finland
Scoliosis, unspecified
3.0
6.9
36
120
M43.1
ICD-10 Finland
Spondylolisthesis
2.0
6.9
86
444
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.8
504
4039
K92.1
ICD-10 Finland
Melaena
1.9
6.8
98
536
U05
ICPC
Urination problems other
1.9
6.8
92
492
L04AD01
ATC
ciclosporin; systemic
3.5
6.8
29
83
A01AB04
ATC
amphotericin B; local oral
1.7
6.8
135
818
M81
ICD-10 Finland
Osteoporosis without pathological fracture
3.6
6.8
28
78
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.5
6.8
22
49
N02AC04
ATC
dextropropoxyphene; oral
1.9
6.8
94
508
S42.0
ICD-10 Finland
Fracture of clavicle
2.7
6.8
44
167
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.8
651
5428
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.1
6.8
35
116
J47
ICD-10 Finland
Bronchiectasis
2.6
6.7
47
184
NB1AD
NOMESCO Finland
Shoulder CT examination
2.6
6.7
45
175
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.6
6.7
47
185
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.6
6.7
47
185
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.7
711
6003
P76
ICPC
Depressive disorder
2.1
6.7
70
339
R4190
NOMESCO Finland
Nutritional therapy
2.7
6.7
43
161
NBU20
NOMESCO Finland
Removal of internal fixation device from shoulder or upper arm
4.9
6.7
20
41
H02AA02
ATC
fludrocortisone; oral
4.2
6.6
23
55
Z01.2
ICD-10 Finland
Dental examination
1.3
6.6
567
4642
U07
ICPC
Urine symptom/complaint other
1.7
6.6
122
725
N06AX16
ATC
venlafaxine; oral
1.6
6.6
182
1204
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
6.6
100
556
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
8.7
6.5
13
15
R63.4
ICD-10 Finland
Abnormal weight loss
2.1
6.5
71
349
M02AA07
ATC
piroxicam; topical
1.3
6.5
752
6420
L99
ICPC
Musculoskeletal disease other
2.4
6.5
50
209
Z50.1
ICD-10 Finland
Other physical therapy
1.8
6.5
110
633
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
6.2
6.5
16
26
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.5
647
5412
WX110
NOMESCO Finland
Local anesthesy
1.3
6.5
993
8805
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
6.5
106
605
K90
ICPC
Stroke/cerebrovascular accident
2.2
6.5
60
273
M87.9
ICD-10 Finland
Osteonecrosis, unspecified
5.7
6.4
17
30
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
2.1
6.4
72
358
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.0
6.3
82
430
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
2.7
6.3
39
145
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
3.0
6.3
34
116
M48.4
ICD-10 Finland
Fatigue fracture of vertebra
8.2
6.3
13
16
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.3
307
2286
N03AF01
ATC
carbamazepine; oral, rectal
1.9
6.3
92
505
R42
ICD-10 Finland
Dizziness and giddiness
1.3
6.3
461
3678
M96.0
ICD-10 Finland
Pseudarthrosis after fusion or arthrodesis
5.5
6.3
17
31
NG1AD
NOMESCO Finland
Knee CT examination
2.9
6.3
36
125
S79.9
ICD-10 Finland
Unspecified injury of hip and thigh
3.6
6.3
26
73
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
9.3
6.3
12
13
RF220
NOMESCO Finland
NA
3.0
6.3
33
111
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.3
6.3
54
239
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.1
6.3
67
328
L04AA01
ATC
[U] ciclosporin; systemic
3.3
6.3
29
89
NDJ40
NOMESCO Finland
Closed reduction of fracture of wrist or hand
3.1
6.3
31
100
K99
ICPC
Cardiovascular disease other
2.2
6.3
57
260
M80.3
ICD-10 Finland
Postsurgical malabsorption osteoporosis with pathological fracture
+∞
6.3
6
*
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
6.2
454
3621
M01AH01
ATC
celecoxib; oral (coxibs)
1.4
6.2
360
2765
R4180
NOMESCO Finland
Podiatric therapy
4.1
6.2
22
54
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
6.2
519
4227
M02AA10
ATC
ketoprofen; topical
1.4
6.2
324
2449
S23.4
ICD-10 Finland
Sprain and strain of ribs and sternum
3.3
6.2
28
85
N03AX09
ATC
lamotrigine; oral
2.3
6.1
51
223
L16
ICPC
Ankle symptom/complaint
1.6
6.1
168
1109
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.1
94
524
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.8
6.1
37
136
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.6
6.1
41
160
N17
ICPC
Vertigo/dizziness
1.5
6.1
244
1750
N04BD01
ATC
selegiline; oral
2.9
6.1
35
122
N03AF02
ATC
oxcarbazepine; oral
2.4
6.1
50
216
NCU20
NOMESCO Finland
Removal of internal fixation device from elbow or forearm
4.0
6.1
22
55
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
6.1
88
482
SPAT1252
SPAT
Overall medication plan or its review
1.6
6.1
146
934
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.6
6.1
138
869
R35
ICD-10 Finland
Polyuria
1.9
6.1
88
483
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
1.9
6.1
86
468
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.1
179
1205
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
1.9
6.1
84
454
N03AG01
ATC
valproic acid; systemic, rectal
1.9
6.0
78
411
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
4.4
6.0
20
46
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
2.6
6.0
41
162
K08.3
ICD-10 Finland
Retained dental root
1.8
6.0
104
603
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
3.5
6.0
26
76
SPAT1153
SPAT
Removal of sutures
1.3
6.0
556
4590
XW000
NOMESCO Finland
Bone marrow biopsy
2.0
6.0
71
360

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1619
8573
5.17
226.21
4.1
2.2
86.0
82.1
nmol/l
6.63
1464
7396
614
1843
4.32
184.16
3.0
3.0
71.9
87.8
ng/l
5.65
497
1491
1699
10449
4.60
166.40
10.4
5.8
1.2
1.2
mmol/l
0.16
1407
8727
659
2308
3.73
155.57
4.0
4.0
1.0
1.1
mmol/l
2.97
565
2073
1555
9437
3.65
144.81
8.9
5.1
1.2
1.2
mmol/l
0.50
1418
8361
467
1452
3.87
129.08
2.1
2.3
—
—
—
0
0
506
1685
3.66
126.07
2.1
2.5
66.5
66.0
g/l
0.62
406
1479
1136
6340
2.77
110.52
5.8
3.5
7.4
7.4
ph
1.52
229
1120
757
3548
2.79
101.92
1.4
1.3
1.1
1.6
u/ml
0.72
195
838
448
1601
3.30
97.64
2.2
2.0
325.3
388.8
nmol/l
5.57
407
1426
1342
8847
2.49
82.27
6.4
4.0
33.6
34.8
g/l
11.40
1235
8057
1166
7410
2.32
74.82
3.9
3.2
2.4
2.4
mmol/l
2.46
971
6208
240
684
3.84
73.04
2.3
3.0
39.1
129.6
mg/l
0.58
179
571
239
683
3.83
72.44
2.3
3.0
23.8
50.3
mg/l
2.20
179
568
231
667
3.77
68.87
2.3
3.0
1.4
1.7
ratio
0.51
14
49
191
499
4.12
65.46
2.3
3.1
—
—
—
0
0
122
225
5.70
63.55
1.2
1.2
—
—
—
0
0
886
5288
2.19
62.85
4.9
3.8
—
—
—
0
0
1778
14156
2.89
61.65
10.6
7.1
81.4
80.5
u/l
0.20
1688
13067
954
5980
2.11
58.36
7.1
5.2
—
—
—
0
0
1263
8806
2.13
57.97
7.6
5.5
0.2
0.2
e9/l
2.15
1091
7468
570
2932
2.31
57.29
1.6
1.4
2.5
2.5
g/l
0.00
298
1508
1224
8464
2.10
57.03
7.4
5.3
0.6
0.6
e9/l
0.59
1054
7071
1228
8510
2.10
56.78
7.4
5.3
0.0
0.0
e9/l
1.63
1062
7119
1162
7968
2.05
54.31
7.7
5.5
2.6
2.7
%
1.77
1057
7258
1237
8679
2.07
54.24
7.5
5.4
1.6
1.9
e9/l
7.18
1070
7392
849
5203
2.08
54.04
2.8
2.4
3.4
3.2
mg/l
0.55
720
4366
1165
8007
2.05
53.97
8.2
5.8
8.8
8.7
%
0.29
1064
7308
1139
7771
2.04
53.78
7.8
5.5
0.6
0.7
%
2.10
1039
7082
1166
8026
2.05
53.67
15.6
9.6
1.3
1.3
inr
0.81
305
2109
568
3002
2.23
52.87
3.1
2.6
0.8
0.8
mmol/l
2.37
505
2717
141
348
4.28
51.94
1.7
2.1
—
—
—
0
0
1173
8155
2.02
51.75
8.0
5.7
24.2
27.0
%
13.40
1064
7398
313
1278
2.71
51.34
1.3
1.2
—
—
—
0
0
1157
8035
2.01
50.84
7.6
5.5
60.5
58.1
%
7.95
1053
7332
1375
10160
2.07
50.62
10.2
8.3
4.4
4.1
e9/l
3.27
1198
8719
1667
13311
2.33
49.50
6.5
4.4
17.8
15.3
mm/h
6.87
1530
12024
1155
8075
1.98
49.10
5.3
3.9
—
—
—
0
0
223
801
3.00
46.27
2.0
2.3
9.8
10.1
g/l
0.47
165
660
156
462
3.57
44.36
1.4
1.5
—
—
—
0
0
1318
9861
1.94
43.40
6.7
5.5
11.4
11.1
umol/l
0.17
1244
9234
741
4628
1.94
42.12
2.0
1.8
1219.5
1190.6
nmol/l
0.35
532
3350
1029
7167
1.87
41.61
3.6
2.8
124.3
115.2
ug/l
0.38
917
6373
540
3033
2.06
41.48
2.7
2.3
10.4
11.6
umol/l
3.34
488
2738
436
2265
2.17
41.09
2.3
2.3
1.9
1.8
%
0.22
376
1950
1602
12927
2.08
41.04
8.6
5.9
1172.9
4667.3
e6/l
2.98
29
180
480
2614
2.09
39.88
2.8
2.3
19.2
19.9
%
0.49
356
2154
151
469
3.40
39.84
1.6
1.3
62.7
58.9
mmol/l
0.52
115
373
1406
10900
1.92
39.72
6.1
4.2
6.6
6.8
mmol/l
3.55
1360
10162
504
2800
2.06
39.65
2.7
2.3
2.3
2.3
g/l
0.51
453
2538
397
2029
2.19
38.78
2.1
1.7
—
—
—
0
0
188
678
2.95
38.54
1.7
2.1
38.4
37.1
g/l
2.46
140
561
870
5873
1.83
37.73
3.3
2.4
59.5
57.6
u/l
0.27
802
5294
787
5161
1.85
37.41
1.8
1.6
21.8
21.9
nmol/l
0.02
650
4266
1126
8243
1.81
37.08
5.3
4.0
—
—
—
0
0
179
646
2.94
36.61
2.1
2.7
0.3
0.3
g/l
0.23
45
188
899
6179
1.81
36.34
2.4
2.1
165.9
164.4
u/l
0.04
832
5714
166
585
3.00
35.41
7.3
5.3
1.2
1.2
mmol/l
0.03
153
525
356
1820
2.16
34.41
2.2
1.9
0.2
0.2
g/l
2.87
314
1681
340
1716
2.18
33.92
2.5
2.3
71.6
70.0
e9/l
0.31
275
1265
275
1277
2.33
33.54
5.7
4.1
—
—
—
0
0
1054
7718
1.75
33.26
5.4
4.2
32.2
108.0
ng/l
0.79
841
5855
1560
12817
1.90
33.14
7.5
5.3
—
—
—
0
0
132
425
3.25
32.81
7.4
5.8
104.0
104.8
mmol/l
0.84
122
384
132
425
3.25
32.81
7.4
5.8
10.7
10.9
mmol/l
0.32
122
384
1225
9478
1.72
30.63
4.1
3.0
60.9
49.7
u/l
1.89
1119
8410
392
2173
1.99
30.12
7.2
5.3
2.1
1.4
mmol/l
2.30
322
1696
1152
8804
1.70
29.78
2.5
2.1
97.8
97.0
pmol/l
0.16
570
3990
55
101
5.57
28.72
1.4
1.7
—
—
—
0
0
598
3856
1.78
28.39
3.8
2.8
478.9
502.6
mosm/kgh2o
2.09
510
3233
214
964
2.36
27.79
8.7
7.2
—
—
—
0
0
235
1103
2.28
27.73
2.9
2.9
9.5
10.4
g/l
2.38
208
981
256
1246
2.20
27.66
7.8
5.7
25.5
24.9
mmol/l
1.82
242
1161
345
1901
1.98
26.71
7.3
5.5
95.6
95.7
%
0.11
328
1826
655
4398
1.72
26.63
3.5
3.0
2.5
2.5
mmol/l
0.41
575
3814
381
2178
1.92
26.45
7.3
5.3
5.2
5.1
kpa
1.27
358
2061
380
2177
1.91
26.18
7.3
5.3
11.4
12.2
kpa
2.47
356
2054
173
730
2.50
25.90
2.0
1.8
1.5
2.0
ug/l
0.34
153
615
919
6781
1.64
25.82
3.7
3.1
1541.8
1631.7
ng/l
0.33
788
5810
325
1785
1.97
25.30
7.6
5.8
113.6
117.1
g/l
2.82
312
1720
377
2197
1.88
24.51
8.0
4.4
—
—
—
0
0
187
842
2.34
24.23
6.4
4.3
1.0
0.9
%
1.34
176
799
192
879
2.31
23.93
1.9
1.8
1.4
1.4
g/l
0.20
170
758
414
2507
1.82
23.72
2.6
1.9
—
—
—
0
0
185
844
2.31
23.24
6.5
4.3
1.9
1.5
%
2.93
173
799
61
147
4.25
23.16
1.2
1.2
28.2
33.6
mmol/l
1.21
46
119
801
5889
1.59
21.72
3.0
2.3
—
—
—
0
0
774
5653
1.59
21.54
4.2
3.3
38.4
48.7
e6/l
0.48
619
4234
1615
14033
1.70
21.14
5.4
4.6
15.5
15.2
pmol/l
3.66
1441
12412
585
4006
1.64
21.14
5.6
4.1
212.7
211.4
ng/l
0.01
516
3414
271
1492
1.94
20.72
6.0
5.1
10.2
10.5
mmol/l
0.24
255
1393
20
16
12.61
20.33
1.7
1.7
—
—
—
0
0
188
917
2.16
20.01
2.0
1.6
1.6
1.6
g/l
0.08
167
782
204
1029
2.09
19.90
4.4
3.4
7.4
7.4
ph
0.24
39
137
40
77
5.28
19.88
1.6
1.8
4.1
7.9
nmol/l
0.55
33
66
1858
16943
2.00
19.25
29.7
16.4
24.2
24.1
mg/l
0.04
1661
13770
204
1042
2.06
19.23
4.5
3.4
5.3
5.2
kpa
0.60
185
938
577
4022
1.60
19.06
3.4
2.6
6.8
7.3
e6/l
0.32
522
3485
262
1471
1.90
18.80
3.9
3.7
0.9
0.8
%
0.19
83
381
486
3272
1.64
18.41
5.9
4.4
—
—
—
0
0
716
5279
1.55
18.39
4.1
3.2
0.5
0.6
e6/l
0.86
574
3948
334
2034
1.77
18.38
4.4
3.1
236.7
231.2
ng/l
0.08
312
1847
243
1341
1.92
18.36
3.6
3.5
0.5
0.5
%
0.25
63
260
560
3908
1.59
18.28
2.0
1.8
1.4
1.4
mg/l
0.04
446
2993
238
1313
1.92
17.99
3.9
3.7
1.3
0.4
%
0.34
72
291
695
5111
1.54
17.96
4.1
3.2
—
—
—
0
0
71
227
3.20
17.88
1.4
1.3
265.3
272.5
mosm/kgh2o
1.34
51
164
427
2806
1.66
17.72
2.2
1.9
29.6
29.5
s
0.08
412
2690
624
4493
1.56
17.68
2.9
2.2
—
—
—
0
0
1785
16160
1.79
17.64
6.9
5.7
2.0
2.1
mu/l
0.33
1611
14378
61
179
3.48
17.60
1.2
1.4
—
—
—
0
0
334
2069
1.73
17.23
1.5
1.3
644.0
642.8
titre
0.00
91
498
141
653
2.24
17.04
2.7
2.0
382.5
744.2
ug/l
0.58
126
608
857
6659
1.49
16.74
4.9
3.8
108.4
142.5
e6/l
0.83
649
4601
55
156
3.60
16.71
1.5
1.2
—
—
—
0
0
298
1802
1.76
16.70
5.5
3.2
1.2
1.2
mmol/l
0.16
280
1525
306
1866
1.75
16.65
4.4
3.0
3.1
2.2
mmol/l
3.25
255
1548
246
1409
1.85
16.50
3.9
3.7
0.1
0.1
%
0.17
82
353
130
595
2.26
16.17
3.5
3.6
—
—
—
0
0
1104
9063
1.47
16.10
6.4
4.7
0.0
0.0
estimate
0.00
207
1592
306
1887
1.73
15.97
4.4
2.9
6.1
5.8
kpa
3.07
293
1833
201
1093
1.93
15.81
2.9
2.9
4.2
4.3
pmol/l
1.12
155
929
1115
9232
1.45
15.16
6.5
4.8
0.0
0.0
estimate
1.08
212
1599
1105
9145
1.45
14.98
8.3
6.3
0.0
0.0
estimate
0.00
203
1561
96
398
2.48
14.92
5.1
3.7
3.4
3.0
mmol/l
0.54
77
289
108
475
2.34
14.75
4.8
3.5
7.4
7.4
ph
0.02
95
389
606
4486
1.50
14.54
4.7
3.6
88.3
89.4
%
0.41
585
4351
302
1919
1.67
14.00
2.6
2.2
9.6
8.0
umol/l
0.28
242
1613
89
368
2.48
13.93
4.1
3.2
—
—
—
0
0
59
198
3.04
13.76
9.5
6.1
13.3
13.2
mg/l
0.04
54
176
551
4100
1.47
12.56
7.2
5.4
1.0
1.0
kg/l
0.37
83
664
61
220
2.83
12.54
2.4
2.6
—
—
—
0
0
376
2584
1.56
12.53
1.3
1.2
—
—
—
0
0
349
2358
1.58
12.53
6.9
5.1
102.7
103.8
mmol/l
3.49
336
2303
457
3287
1.50
12.31
3.3
2.7
1.5
1.6
e6/l
0.15
256
1823
245
1529
1.68
12.09
7.2
5.6
—
—
—
0
0
715
5619
1.42
12.04
3.2
2.9
5.4
5.8
mmol/l
2.94
596
4567
41
120
3.47
11.95
1.3
1.3
5.7
6.9
g/l
1.24
25
87
41
120
3.47
11.95
1.3
1.3
0.3
0.4
g/l
2.14
25
87
41
120
3.47
11.95
1.3
1.3
2.0
2.7
g/l
2.22
25
87
41
121
3.44
11.81
1.3
1.3
—
—
—
0
0
260
1664
1.64
11.63
6.2
4.7
1.4
1.3
mmol/l
0.65
248
1595
251
1601
1.65
11.37
3.7
2.6
4.4
4.4
kpa
0.17
239
1548
138
739
1.93
11.35
4.5
3.5
—
—
—
0
0
27
61
4.47
11.20
1.8
1.5
17.3
16.3
nmol/l
0.16
19
55
55
200
2.80
11.16
1.7
1.7
—
—
—
0
0
36
103
3.54
10.88
2.6
1.4
1.0
1.0
e9/l
0.03
22
71
45
152
3.00
10.44
4.1
3.1
—
—
—
0
0
287
1930
1.57
10.41
1.7
1.4
—
—
—
0
0
1586
14429
1.43
10.36
31.9
18.6
36.5
37.3
%
1.87
837
8653
89
421
2.16
10.28
3.8
2.6
26.5
25.6
mmol/l
0.88
84
357
13
15
8.72
10.23
1.5
1.5
42.7
41.4
umol/l
0.03
13
15
168
991
1.76
10.15
3.1
2.2
1.2
1.1
%
1.35
168
985
1829
17145
1.60
10.13
29.0
15.9
—
—
—
0
0
590
4594
1.40
10.11
1.9
1.7
55696686.4
19760110.7
pmol/l
0.55
474
3578
91
445
2.09
9.67
2.0
1.5
0.2
0.2
g/l
0.23
83
418
66
283
2.38
9.63
2.7
3.6
1.1
1.4
%
0.31
51
205
1888
17875
1.68
9.58
34.8
19.8
138.6
139.5
mmol/l
28.15
1854
17341
200
1260
1.65
9.48
1.6
1.4
—
—
—
0
0
51
195
2.66
9.45
1.4
1.5
0.8
0.7
g/l
0.07
34
147
116
624
1.91
9.44
1.4
1.2
1.1
1.5
u/ml
—
7
53
92
456
2.07
9.44
2.0
1.5
1.1
1.2
g/l
1.31
85
429
118
639
1.90
9.42
5.0
3.8
25.6
25.2
mmol/l
0.53
102
567
1889
17905
1.67
9.31
35.0
20.0
4.0
4.0
mmol/l
0.63
1852
17340
407
3006
1.44
9.30
3.5
2.9
3.8
4.4
e6/l
0.54
207
1556
88
432
2.08
9.27
2.1
2.1
116.9
124.5
g/l
2.54
68
312
180
1111
1.68
9.23
3.5
3.3
4.1
4.1
e9/l
0.08
110
756
77
360
2.18
9.19
2.5
2.4
1.7
1.6
mg/l
0.35
72
317
64
277
2.35
9.16
2.7
2.0
34.9
31.7
umol/l
0.40
47
218
151
892
1.75
9.09
4.5
3.0
24.7
24.5
mmol/l
0.27
133
798
161
972
1.71
8.97
3.1
2.2
0.6
0.7
%
0.19
156
924
57
237
2.45
8.92
1.7
1.3
61.8
39.6
mu/l
0.40
51
205
114
622
1.88
8.90
1.5
1.4
251.3
282.6
ug/g
0.81
65
356
82
399
2.10
8.85
3.1
2.3
14.7
15.7
%
1.78
46
189
138
801
1.77
8.83
1.6
1.2
217.4
166.5
u/ml
0.32
126
726
32
98
3.30
8.76
1.2
1.2
0.4
1.7
u/ml
0.62
21
45
23
56
4.14
8.72
2.5
1.9
—
—
—
0
0
23
56
4.14
8.72
2.7
1.3
572.9
414.9
e6/l
0.46
18
48
36
119
3.06
8.71
1.5
1.3
2137.3
1824.4
ml
—
8
31
26
70
3.75
8.62
1.6
1.7
17.2
16.3
pmol/l
0.35
19
51
52
216
2.44
8.18
1.2
1.2
229.1
281.6
pmol/l
0.84
39
165
184
1181
1.61
8.10
1.4
1.4
—
—
—
0
0
87
448
1.98
8.08
1.9
1.6
4.9
4.4
iu/l
0.13
25
128
81
407
2.03
8.06
3.0
2.0
11.4
12.4
mg/l
0.60
62
376
271
1899
1.49
8.05
3.0
2.4
5.0
5.4
ug/l
0.16
200
1556
44
173
2.58
7.77
2.7
3.3
62.3
57.6
%
0.67
30
97
542
4314
1.35
7.76
2.8
2.5
5688.1
7286.3
umol/l
0.30
446
3537
164
1036
1.63
7.71
4.1
2.8
26.6
25.5
mmol/l
3.04
158
1011
563
4512
1.34
7.69
6.2
4.4
—
—
—
0
0
65
306
2.16
7.68
2.9
2.4
—
—
—
0
0
56
248
2.29
7.66
1.2
1.3
—
—
nmol/l
—
0
0
11
15
7.37
7.55
1.1
1.1
—
—
—
0
0
28
87
3.25
7.53
1.9
1.4
20.5
12.6
%
—
10
25
385
2919
1.39
7.44
34.1
29.2
1.4
1.4
inr
0.21
42
369
46
190
2.45
7.35
3.0
3.8
—
—
—
0
0
66
321
2.09
7.19
4.2
3.2
60.1
58.8
%
0.28
66
321
172
1126
1.58
6.98
1.4
1.3
—
—
—
0
0
150
955
1.62
6.85
1.4
1.3
—
—
—
0
0
56
261
2.18
6.82
1.2
1.4
—
—
—
0
0
1896
18189
1.54
6.46
42.9
24.7
7.0
6.7
e9/l
4.41
1850
17491
27
91
2.99
6.39
2.6
1.8
7.4
7.4
ph
—
7
30
1895
18184
1.53
6.37
42.8
24.7
262.4
255.0
e9/l
4.35
1852
17564
1895
18186
1.53
6.35
42.6
24.6
30.3
30.2
pg
2.25
1869
17787
1895
18186
1.53
6.35
42.7
24.6
92.2
91.5
fl
8.21
1869
17787
1895
18186
1.53
6.35
42.9
24.7
4.1
4.3
e12/l
40.61
1850
17484
1895
18189
1.53
6.31
43.2
24.9
124.3
129.0
g/l
44.88
1869
17803
591
4897
1.29
6.11
7.8
5.3
0.0
0.0
estimate
0.50
204
1572
24
78
3.10
6.04
1.3
1.2
26.0
24.6
u/l
0.13
17
57
1853
17731
1.45
6.00
15.7
11.2
21.3
22.3
u/l
2.29
1773
16856
85
483
1.79
5.93
2.0
1.6
6297.8
14485.7
e6/l
2.32
61
353
18
49
3.70
5.92
1.6
1.4
—
—
—
0
0
20
59
3.41
5.86
1.4
1.5
51.5
131.6
umol/l
1.85
15
35
180
1240
1.49
5.81
2.6
2.6
—
—
—
0
0
556
4598
1.29
5.79
8.1
6.4
—
—
—
0
0
170
1167
1.50
5.59
1.4
1.4
—
—
—
0
0
114
719
1.62
5.46
1.3
1.2
—
—
—
0
0
855
7488
1.24
5.38
15.9
9.8
0.0
0.0
e9/l
0.16
702
6004
255
1906
1.39
5.31
2.2
1.7
263.9
154.9
ug/g
1.70
198
1427
17
49
3.49
5.17
1.5
1.2
1.9
2.1
umol/l
0.70
17
44
19
59
3.24
5.17
1.3
1.1
1.1
1.1
ratio
—
5
18
36
158
2.30
5.13
1.4
1.3
—
—
—
0
0
36
158
2.30
5.13
1.4
1.3
—
—
—
0
0
36
158
2.30
5.13
1.4
1.3
—
—
—
0
0
36
158
2.30
5.13
1.4
1.3
—
—
—
0
0
44
214
2.08
4.90
5.4
4.1
6.9
7.5
mmol/l
0.57
39
177
57
305
1.89
4.86
1.3
1.3
—
—
—
0
0
68
386
1.79
4.82
3.0
2.2
—
—
—
0
0
50
257
1.97
4.80
1.2
1.2
—
—
—
0
0
122
809
1.54
4.75
5.2
3.9
—
—
—
0
0
135
918
1.50
4.68
8.0
6.5
25.3
24.6
mmol/l
0.82
126
837
18
58
3.12
4.64
3.4
1.5
571.7
629.4
e6/l
—
9
25
16
48
3.35
4.60
1.9
2.0
76.3
52.8
umol/l
—
9
30
342
2738
1.30
4.47
1.3
1.2
29.1
15.5
u/ml
1.16
110
935
548
4648
1.24
4.44
6.0
4.6
—
—
—
0
0
17
55
3.11
4.36
1.8
1.2
27.3
31.4
umol/l
0.73
17
55
7
6
11.70
4.27
1.0
1.2
—
—
—
0
0
360
2930
1.28
4.13
1.3
1.3
36.8
41.0
iu/ml
0.22
132
949
66
392
1.71
4.05
1.2
1.2
—
—
—
0
0
38
189
2.03
4.04
4.1
4.2
342.5
360.2
umol/l
0.34
33
161
27
117
2.33
4.02
1.0
1.0
288.5
352.1
ng/l
0.76
15
74
9
14
6.45
3.98
1.0
1.0
—
—
—
0
0
21
81
2.61
3.97
1.0
1.1
—
—
—
0
0
23
93
2.49
3.96
1.1
1.1
—
—
—
0
0
227
1748
1.34
3.92
2.6
2.2
34.3
37.3
u/l
0.45
200
1463
168
1236
1.39
3.88
1.6
1.6
—
—
—
0
0
27
119
2.29
3.88
1.0
1.0
781.2
675.5
ng/l
0.34
13
74
1671
15953
1.25
3.85
6.3
6.5
39.8
40.6
mmol/mol
3.46
1464
14282
39
200
1.97
3.83
1.5
1.2
44.7
45.3
u/ml
—
8
11
47
257
1.85
3.82
2.2
2.7
—
—
—
0
0
18
66
2.74
3.75
1.1
1.1
—
—
—
0
0
36
181
2.01
3.74
1.6
1.4
14624.9
220548.5
e6/l
2.00
19
126
64
387
1.67
3.71
1.1
1.2
1184.0
1044.7
titre
—
5
17
94
627
1.52
3.63
1.5
1.6
—
—
—
0
0
25
111
2.27
3.55
1.3
1.5
—
—
—
0
0
16
57
2.82
3.52
1.7
1.4
27.2
33.9
%
—
9
37
16
57
2.82
3.52
2.2
1.4
—
—
—
0
0
18
70
2.59
3.38
2.2
2.2
—
—
—
0
0
1413
13325
1.19
3.38
36.1
20.4
14.4
13.9
%
21.51
1395
12960
13
42
3.11
3.37
4.9
2.0
—
—
—
0
0
40
217
1.86
3.37
1.1
1.2
—
—
—
0
0
25
114
2.21
3.35
1.2
1.2
—
—
—
0
0
52
309
1.70
3.25
1.4
1.3
7.5
15.7
e6/l
0.89
43
238
52
310
1.69
3.21
1.5
1.3
301.9
1322.8
e6/l
1.56
45
257
17
66
2.59
3.21
3.1
8.2
74.8
65.2
mg/l
0.17
12
38
12
39
3.09
3.09
1.4
1.6
—
—
—
0
0
155
1175
1.35
3.02
8.4
6.1
93.4
93.9
%
0.64
155
1169
31
161
1.94
3.00
1.2
1.1
235.0
344.9
u/ml
1.99
24
89
80
540
1.50
2.98
2.7
1.9
23.0
21.4
s
0.67
68
487
132
978
1.37
2.98
1.1
1.2
93.6
136.1
iu/ml
0.87
35
346
17
69
2.48
2.96
1.8
1.3
0.8
1.0
g/l
2.46
17
69
16
63
2.55
2.95
2.9
2.0
39.0
43.1
%
—
9
21
36
198
1.83
2.94
1.3
1.2
—
—
—
0
0
64
413
1.57
2.92
2.2
2.9
218.1
1153.2
u/ml
0.78
57
368
15
58
2.60
2.87
3.2
2.0
—
—
—
0
0
239
1937
1.26
2.85
1.3
1.2
—
—
—
0
0
37
208
1.79
2.83
1.0
1.0
—
—
—
0
0
664
5949
1.17
2.81
5.1
4.4
—
—
—
0
0
11
36
3.07
2.81
1.5
1.3
1.6
1.8
mmol/l
—
5
19
360
4208
0.82
2.80
3.4
3.4
—
—
—
0
0
89
626
1.44
2.72
4.9
3.3
3.8
3.8
mmol/l
0.58
81
590
78
535
1.48
2.72
2.0
2.3
—
—
—
0
0
39
227
1.73
2.67
1.7
1.5
66.6
59.5
%
0.55
25
145
27
141
1.93
2.60
1.0
1.2
—
—
—
0
0
51
322
1.60
2.59
1.9
1.5
—
—
—
0
0
65
435
1.51
2.56
1.4
1.2
1.6
2.6
u/ml
—
6
54
102
747
1.38
2.51
1.9
2.7
181.0
1532.9
u/ml
0.88
85
628
58
381
1.54
2.50
1.1
1.1
193.3
90.5
titre
—
6
19
30
165
1.83
2.49
1.1
1.2
1.9
3.8
u/ml
—
7
70
11
39
2.83
2.47
2.0
2.8
—
—
—
0
0
211
1718
1.25
2.44
5.8
4.1
—
—
—
0
0
39
234
1.68
2.43
3.0
3.1
—
—
—
0
0
29
161
1.81
2.35
1.8
1.5
21.6
31.2
%
1.14
22
100
31
178
1.75
2.26
1.3
1.2
122.7
123.2
u/ml
—
7
34
279
2361
1.21
2.26
2.7
3.6
12.4
18.4
ug/l
0.34
233
1926
33
194
1.71
2.23
1.0
1.0
—
—
—
0
0
13
54
2.42
2.20
1.2
1.3
—
—
—
0
0
6
14
4.30
2.15
2.8
4.0
—
—
—
0
0
29
167
1.75
2.11
1.1
1.1
—
—
—
0
0
95
711
1.35
2.09
3.7
3.4
0.9
0.8
nmol/l
0.79
72
543
17
82
2.08
2.07
1.7
1.3
66.1
48.6
u/l
—
10
68
13
56
2.33
2.05
1.1
1.1
—
—
—
0
0
6
15
4.01
2.04
1.2
1.0
—
—
—
0
0
19
97
1.97
2.00
1.2
1.3
—
—
—
0
0
9
32
2.82
2.00
34.3
21.8
5.6
7.3
ug/l
—
9
26
182
1495
1.24
1.99
7.6
4.9
—
—
—
0
0
51
346
1.49
1.95
1.9
1.5
—
—
—
0
0
5
11
4.55
1.94
3.2
1.5
16.3
18.6
umol/l
—
5
11
1710
16630
1.17
1.90
5.1
5.2
5.8
6.0
mmol/l
6.51
1471
14611
115
1453
0.78
1.86
1.4
1.6
—
—
—
0
0
20
354
0.56
1.84
1.5
1.8
—
—
—
0
0
1305
12479
1.13
1.83
5.2
4.3
—
—
—
0
0
16
80
2.01
1.80
1.3
1.4
—
—
—
0
0
13
60
2.17
1.77
2.6
2.7
29.8
28.5
umol/l
—
8
42
14
67
2.10
1.76
1.1
1.1
—
—
—
0
0
21
359
0.58
1.72
1.1
1.3
—
—
—
0
0
26
156
1.68
1.69
1.5
1.2
—
—
—
0
0
42
284
1.49
1.67
1.2
1.3
—
—
—
0
0
30
188
1.60
1.66
1.2
1.2
—
—
—
0
0
23
134
1.72
1.66
3.0
2.8
—
—
—
0
0
23
135
1.71
1.62
1.3
1.6
8.9
10.4
%
0.91
23
135
5
130
0.38
1.62
1.6
1.2
1.5
1.4
nmol/l
—
5
115
38
254
1.51
1.61
1.3
1.4
26.6
31.3
g/l
1.14
27
233
8
32
2.51
1.59
1.4
1.5
—
—
—
0
0
14
71
1.98
1.54
2.6
1.5
0.1
0.2
nmol/l
—
6
49
10
44
2.28
1.53
1.0
1.2
—
—
—
0
0
29
186
1.57
1.48
1.1
1.1
—
—
—
0
0
5
16
3.13
1.44
20.2
17.9
4.9
4.9
mmol/l
—
5
16
14
73
1.92
1.44
1.1
1.1
—
—
—
0
0
17
95
1.80
1.43
1.9
1.5
—
—
—
0
0
19
110
1.73
1.43
3.4
3.0
—
—
—
0
0
15
81
1.86
1.40
2.1
1.6
—
—
—
0
0
14
74
1.90
1.39
1.1
1.1
—
—
—
0
0
9
41
2.20
1.37
2.1
2.0
4.2
2.0
mmol/l
—
9
35
106
860
1.25
1.37
1.3
1.2
—
—
—
0
0
12
61
1.97
1.32
1.5
1.8
—
—
—
0
0
25
160
1.57
1.31
1.2
1.2
—
—
—
0
0
6
24
2.50
1.30
1.8
1.5
—
—
—
0
0
110
903
1.23
1.29
1.3
1.3
—
51.3
—
0
41
15
84
1.79
1.27
1.2
1.2
128.3
334.9
u/l
0.99
15
78
8
35
2.29
1.27
1.4
1.3
101.4
101.5
ng/l
—
8
35
34
237
1.44
1.23
1.4
1.4
4138.2
1353.3
e6/l
0.45
26
180
75
593
1.27
1.22
1.3
1.2
—
—
—
0
0
5
19
2.64
1.21
1.0
1.2
—
—
—
0
0
166
1427
1.18
1.21
3.8
3.9
42.2
89.4
u/ml
2.55
161
1364
6
26
2.31
1.18
1.0
2.4
—
—
—
0
0
26
382
0.68
1.18
1.5
1.4
—
—
—
0
0
46
342
1.35
1.16
1.1
1.3
—
—
—
0
0
163
1405
1.17
1.16
5.3
3.9
—
—
—
0
0
72
572
1.27
1.14
16.3
11.0
—
—
—
0
0
8
40
2.00
1.12
1.4
1.4
—
—
—
0
0
31
434
0.71
1.10
1.2
1.1
—
—
—
0
0
1365
13245
1.09
1.10
39.5
22.6
328.1
329.1
g/l
3.73
1356
13083
8
41
1.95
1.08
1.1
1.0
—
—
—
0
0
67
532
1.27
1.08
1.2
1.2
—
—
—
0
0
13
74
1.76
1.06
1.1
1.1
—
—
—
0
0
7
33
2.12
1.05
1.0
1.3
—
—
—
0
0
16
98
1.64
1.03
1.3
1.6
14.4
12.7
umol/l
0.32
16
91
29
204
1.43
1.03
1.2
1.4
—
—
—
0
0
11
60
1.84
1.03
1.2
1.0
—
—
—
0
0
18
114
1.58
1.02
1.5
1.2
—
—
—
0
0
44
333
1.33
1.02
1.1
1.1
—
—
—
0
0
9
47
1.92
1.02
1.0
1.1
—
—
—
0
0
9
48
1.88
1.00
1.7
1.4
—
—
—
0
0
19
124
1.54
0.96
15.4
15.9
—
—
—
0
0
10
54
1.86
0.96
1.2
1.3
125.0
138.7
nmol/l
—
10
54
7
37
1.89
0.94
1.7
1.3
—
—
—
0
0
6
28
2.15
0.91
1.0
1.0
—
—
—
0
0
15
94
1.60
0.90
2.5
1.8
9.6
9.3
mmol/l
—
9
75
12
71
1.69
0.88
1.1
1.1
—
—
—
0
0
6
30
2.00
0.87
1.0
1.0
—
—
—
0
0
17
252
0.67
0.86
1.1
1.1
—
—
—
0
0
8
45
1.78
0.84
1.1
1.0
—
—
—
0
0
415
3877
1.09
0.82
1.4
1.3
—
—
—
0
0
8
47
1.70
0.80
1.1
1.1
—
—
—
0
0
1694
16673
1.09
0.80
5.1
5.4
2.6
2.7
mmol/l
5.55
1464
14753
1564
15345
1.08
0.79
4.0
4.2
1.2
1.3
mmol/l
4.96
1337
13310
10
59
1.70
0.75
1.0
1.0
—
—
—
0
0
10
59
1.70
0.75
1.4
1.2
—
—
—
0
0
1641
16142
1.08
0.75
4.5
4.7
4.7
4.7
mmol/l
0.84
1418
14311
30
227
1.33
0.74
2.2
2.4
—
—
—
0
0
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
241
2212
1.10
0.71
1.4
1.3
—
—
—
0
0
11
68
1.62
0.71
1.2
1.1
—
—
—
0
0
16
109
1.47
0.71
2.7
1.6
—
—
—
0
0
143
1277
1.13
0.70
1.2
1.3
—
—
—
0
0
7
43
1.63
0.67
1.3
1.1
—
—
—
0
0
7
44
1.59
0.65
1.3
1.2
215.1
121.9
nmol/l
—
7
27
32
251
1.28
0.64
2.0
1.7
—
—
—
0
0
8
128
0.62
0.64
1.3
1.1
—
—
—
0
0
26
199
1.31
0.62
1.2
1.2
263.6
335.4
nmol/l
1.12
18
167
5
30
1.67
0.61
1.0
1.4
—
—
—
0
0
24
182
1.32
0.61
1.3
1.5
—
—
—
0
0
40
325
1.24
0.61
3.3
2.2
—
—
—
0
0
16
113
1.42
0.61
2.4
2.2
—
—
—
0
0
27
209
1.30
0.60
1.3
1.4
271197.7
56594.2
e6/l
0.36
13
121
8
52
1.54
0.59
1.1
1.1
—
—
—
0
0
25
192
1.31
0.59
1.6
1.4
—
—
—
0
0
28
221
1.27
0.55
1.5
1.2
—
—
—
0
0
6
38
1.58
0.54
1.8
1.1
—
—
—
0
0
9
61
1.48
0.53
1.6
1.6
—
—
—
0
0
22
281
0.78
0.51
1.0
1.5
0.7
0.8
nmol/l
0.10
16
217
62
713
0.87
0.51
1.4
1.4
—
—
—
0
0
750
7267
1.05
0.50
2.2
2.2
—
—
—
0
0
12
167
0.72
0.49
1.0
1.1
—
—
—
0
0
1616
15962
1.06
0.48
4.6
4.7
1.7
1.6
mmol/l
5.16
1396
14057
7
47
1.49
0.47
1.3
1.3
—
—
—
0
0
34
283
1.20
0.45
1.1
1.1
—
—
—
0
0
48
556
0.86
0.45
3.3
3.8
35.8
39.5
u/ml
0.12
48
542
12
86
1.40
0.44
1.8
1.9
553.4
484.4
min
—
5
61
15
195
0.77
0.41
1.2
1.1
—
—
—
0
0
14
105
1.34
0.41
1.4
1.2
—
—
—
0
0
15
114
1.32
0.40
1.5
1.1
—
—
—
0
0
18
141
1.28
0.40
1.3
1.3
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
481
4648
1.05
0.36
1.7
1.6
1.2
1.3
mmol/l
3.10
400
3821
6
42
1.43
0.35
1.0
1.1
1670.7
1890.7
miu/ml
—
6
42
187
1765
1.07
0.34
1.4
1.3
—
—
—
0
0
19
155
1.23
0.32
2.9
2.8
30.9
13.6
mg/l
0.34
14
106
11
83
1.33
0.32
2.0
1.4
2.0
1.8
%
—
6
17
47
423
1.11
0.27
5.6
3.9
17.5
25.7
mg/l
1.94
34
266
19
160
1.19
0.25
1.3
1.2
—
71.9
—
0
8
9
74
1.22
0.25
2.3
2.8
—
—
—
0
0
7
95
0.74
0.22
1.0
1.1
—
—
—
0
0
17
144
1.18
0.22
1.2
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
14
165
0.85
0.19
1.7
1.7
—
—
—
0
0
6
51
1.18
0.19
1.3
1.3
—
—
—
0
0
11
90
1.22
0.19
2.5
1.7
—
64.2
—
0
6
21
184
1.14
0.19
1.2
1.6
—
—
—
0
0
7
61
1.15
0.17
1.4
4.0
52.2
57.7
%
—
7
56
7
62
1.13
0.17
12.0
5.4
13.6
13.5
%
—
7
62
566
5567
1.02
0.17
3.2
3.0
1188.5
324.7
mg/l
1.62
324
3129
17
194
0.88
0.16
2.1
2.3
2.7
2.1
u/field
—
6
52
20
225
0.89
0.16
2.9
2.9
—
—
—
0
0
16
139
1.15
0.16
1.8
2.5
7.6
7.0
mmol/l
—
9
94
13
112
1.16
0.14
5.8
5.2
—
—
—
0
0
92
881
1.05
0.14
2.6
2.1
—
—
—
0
0
9
108
0.83
0.13
1.0
1.1
—
—
—
0
0
9
108
0.83
0.13
1.0
1.1
—
—
—
0
0
11
98
1.12
0.07
3.9
5.2
—
—
—
0
0
15
137
1.10
0.07
1.3
1.4
—
—
—
0
0
33
315
1.05
0.06
1.9
1.5
—
—
—
0
0
118
1199
0.98
0.04
5.8
4.0
—
—
—
0
0
13
121
1.07
0.03
1.2
1.1
—
—
—
0
0
588
5906
0.99
0.03
3.8
3.7
16.4
8.0
mg/mmol
1.52
326
3309
66
652
1.01
0.01
8.0
5.2
—
—
—
0
0
11
104
1.06
0.01
3.9
5.0
—
—
—
0
0
32
326
0.98
0.00
1.0
1.1
—
—
—
0
0
37
365
1.01
0.00
2.4
2.2
98.5
39.4
ug/min
0.49
17
198
12
118
1.02
0.00
1.8
2.1
731.2
609.1
ml
—
5
74
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
343.7
—
0
6
0
6
0.00
0.00
0.0
2.2
—
1.6
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
75
0.93
0.00
1.1
1.3
—
—
—
0
0
5
49
1.02
0.00
1.0
1.3
—
11.7
%
—
0
7
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
50
500
1.00
0.00
2.7
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint OSTPOPATFRCTURE_POSTEMENO and mortality.

Females

Parameter HR [95% CI] p-value
OSTPOPATFRCTURE_POSTEMENO 1.727 [1.55, 1.92] < 0.001
Birth year 0.996 [0.99, 1.0] 0.258

During the follow-up period (1.1.1998 — 31.12.2019), 8086 out of 16030 females with OSTPOPATFRCTURE_POSTEMENO died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have OSTPOPATFRCTURE_POSTEMENO.

N-year risk Females Males
1 0.188% No data
5 0.901% No data
10 2.339% No data
15 4.592% No data
20 8.454% No data

Relationships between endpoints

Index endpoint: OSTPOPATFRCTURE_POSTEMENO – Postmenopausal osteoporosis with pathological fracture

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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