Sunburn

L12_SUNBURN

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L55
  • Hospital discharge: ICD-9 6927A
  • Cause of death: ICD-10 L55
  • Cause of death: ICD-9 6927A

2 out of 7 registries used, show all original rules.

74

4. Check minimum number of events

None

74

5. Include endpoints

None

74

6. Filter based on genotype QC (FinnGen only)

72

Control definitions (FinnGen only)

Control exclude
L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L55-L59
Name in latin
Erythema solare

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 631 298 326
Only index persons 553 272 281
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 37.42 44.67 30.51
Only index persons 36.73 43.53 30.16

-FinnGen-

Key figures

All Female Male
Number of individuals 72 37 35
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 44.85 46.71 42.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
74
Matched controls
740
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L55.9
ICD-10 Finland
Sunburn, unspecified
+∞
36.5
32
*
L55.0
ICD-10 Finland
Sunburn of first degree
+∞
20.8
19
*
L55.8
ICD-10 Finland
Other sunburn
+∞
11.8
11
*
L55.1
ICD-10 Finland
Sunburn of second degree
+∞
8.5
8
*
6927A
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERYTHEMA SOLARE]
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
20
62
4.05
5.97
3.1
2.0
16.59
25.16
%
2.24
20
53
22
78
3.59
5.39
2.9
1.9
10.60
14.31
umol/l
1.91
22
70
45
259
2.88
4.67
7.7
6.6
—
—
—
0
0
20
74
3.33
4.53
3.1
1.9
2.30
2.41
g/l
0.32
20
65
31
150
2.84
4.42
3.1
2.6
361.24
8429.30
umol/l
1.06
25
128
46
276
2.76
4.28
7.9
6.0
0.04
0.04
e9/l
0.44
40
252
43
250
2.72
4.25
9.8
8.0
0.00
0.00
e9/l
0.50
35
208
46
277
2.75
4.24
7.9
6.0
0.65
0.55
e9/l
1.41
40
252
31
155
2.72
4.10
3.3
2.0
406.16
171.33
u/l
0.43
31
150
46
286
2.61
3.84
7.8
5.9
1.94
1.80
e9/l
0.52
41
267
46
288
2.58
3.76
8.2
5.9
0.21
0.19
e9/l
0.33
40
267
13
42
3.54
3.57
6.2
2.5
—
—
—
0
0
13
40
3.72
3.35
6.5
5.5
—
—
—
0
0
15
56
3.11
3.29
6.2
3.6
1.04
1.01
mmol/l
0.34
15
51
6
8
8.03
3.11
1.3
1.0
—
—
—
0
0
50
343
2.41
3.11
11.1
10.1
4.76
4.12
e9/l
1.04
45
309
26
138
2.36
2.89
5.5
3.8
—
—
—
0
0
6
10
6.41
2.75
7.0
1.2
—
—
—
0
0
35
219
2.13
2.57
7.7
4.9
1.20
1.21
mmol/l
0.27
30
207
5
8
6.60
2.41
1.2
1.1
—
—
—
0
0
15
67
2.55
2.36
1.7
1.3
—
—
—
0
0
7
18
4.18
2.31
11.6
6.4
24.79
24.82
mmol/l
—
7
18
7
20
3.75
2.11
6.1
1.2
—
—
—
0
0
5
10
5.27
2.10
1.0
1.0
—
—
—
0
0
14
64
2.46
2.10
1.1
1.3
—
—
—
0
0
24
142
2.02
1.96
4.6
2.9
0.15
0.43
e6/l
1.02
19
112
50
381
1.96
1.93
5.6
4.0
—
—
—
0
0
6
17
3.74
1.88
1.2
1.1
—
—
—
0
0
8
30
2.86
1.78
8.1
6.5
21.96
24.71
mmol/l
—
8
30
5
13
4.04
1.74
1.2
1.1
—
—
—
0
0
12
57
2.32
1.65
2.2
3.0
1.61
1.65
%
0.08
12
51
29
193
1.83
1.64
2.2
1.7
89.86
98.31
pmol/l
0.28
13
95
18
102
2.01
1.63
1.7
1.3
0.95
13.71
u/ml
—
8
46
53
426
1.86
1.58
3.2
4.1
14.90
14.79
pmol/l
0.13
47
399
14
73
2.13
1.56
1.9
1.6
—
—
—
0
0
5
15
3.49
1.55
11.4
1.4
—
—
—
0
0
6
21
3.02
1.54
5.5
3.0
0.63
0.75
%
—
6
21
7
28
2.65
1.49
1.6
1.5
—
—
—
0
0
21
130
1.86
1.47
1.8
1.6
1.24
0.80
mg/l
0.32
14
103
68
606
2.50
1.46
26.7
12.1
26.77
21.32
mg/l
0.54
59
464
18
106
1.92
1.46
6.0
3.1
205.33
257.57
ng/l
—
9
80
9
40
2.42
1.46
5.9
3.0
—
—
—
0
0
22
139
1.83
1.45
4.0
3.0
2808.52
503.60
mg/l
0.37
13
94
7
29
2.56
1.43
6.1
1.2
—
—
—
0
0
23
148
1.80
1.43
4.9
3.4
5.88
10.20
mg/mmol
0.41
14
96
35
255
1.71
1.42
25.0
12.3
1.31
1.19
inr
—
9
78
14
77
2.01
1.37
1.3
1.3
—
—
—
0
0
9
43
2.24
1.36
2.7
4.1
—
0.08
—
0
12
6
24
2.63
1.33
5.5
3.0
1.30
1.64
%
—
6
24
27
186
1.71
1.32
5.3
3.6
118.94
70.28
e6/l
0.18
20
135
26
180
1.69
1.24
2.4
2.1
—
—
—
0
0
12
65
2.01
1.22
9.1
6.1
105.58
103.43
mmol/l
0.93
12
65
7
30
2.47
1.16
6.1
1.2
—
—
—
0
0
7
31
2.39
1.14
6.1
1.2
—
—
—
0
0
7
31
2.39
1.14
6.3
1.2
—
—
—
0
0
8
41
2.06
1.12
1.4
1.8
—
—
—
0
0
23
158
1.66
1.12
4.8
3.0
77.04
40.10
e6/l
0.23
18
126
28
203
1.61
1.10
3.7
3.7
18.33
53.89
ng/l
0.98
19
122
35
271
1.55
1.03
4.1
3.7
0.00
0.00
estimate
—
7
48
7
36
2.04
1.00
11.3
6.8
—
—
—
0
0
35
273
1.54
0.99
5.8
5.1
0.00
0.00
estimate
—
7
46
69
640
2.15
0.98
22.1
10.9
—
—
—
0
0
16
104
1.69
0.94
1.8
1.3
37.54
23.63
iu/ml
—
8
35
35
276
1.51
0.93
4.4
3.7
0.00
0.00
estimate
—
7
43
6
31
2.02
0.86
7.0
1.2
—
—
—
0
0
43
359
1.47
0.83
5.6
4.1
—
621.83
—
0
6
20
143
1.55
0.81
5.3
2.8
—
—
—
0
0
21
152
1.53
0.81
7.7
7.0
—
—
—
0
0
14
92
1.64
0.79
1.5
1.7
—
—
—
0
0
59
534
1.52
0.68
4.9
4.6
1.93
1.93
mu/l
0.00
52
494
46
401
1.39
0.63
3.6
3.5
—
—
—
0
0
18
133
1.47
0.63
6.6
3.4
—
—
—
0
0
0
20
0.00
0.61
0.0
2.2
—
4.14
—
0
8
16
116
1.48
0.61
3.9
3.9
—
—
—
0
0
18
134
1.45
0.60
5.5
3.9
0.00
0.00
estimate
—
7
45
23
181
1.39
0.58
3.3
2.9
2.33
2.36
mmol/l
0.34
17
160
17
129
1.41
0.52
2.2
1.8
—
—
—
0
0
21
168
1.35
0.47
3.7
2.8
—
—
—
0
0
14
180
0.73
0.43
1.4
1.4
—
—
—
0
0
27
227
1.30
0.43
2.2
1.8
—
—
—
0
0
5
32
1.60
0.43
1.4
2.4
0.06
0.12
e6/l
—
5
32
67
637
1.55
0.43
27.2
14.1
80.33
74.97
umol/l
1.11
67
637
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
5
34
1.50
0.41
4.0
4.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
9
66
1.41
0.40
1.7
1.6
—
—
—
0
0
9
66
1.41
0.40
1.2
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
2.0
—
—
—
0
0
6
41
1.50
0.37
1.3
1.9
1.73
6.44
ug/l
—
6
36
6
41
1.50
0.37
2.2
1.5
—
—
—
0
0
19
160
1.25
0.29
4.4
3.2
—
—
—
0
0
57
539
1.25
0.28
6.5
4.9
39.21
39.74
mmol/mol
0.19
52
512
5
39
1.30
0.23
1.2
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
71.10
—
0
10
0
10
0.00
0.21
0.0
3.2
—
19.60
—
0
10
6
47
1.30
0.21
1.3
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.3
—
6.21
—
0
13
6
77
0.76
0.16
3.0
1.9
—
—
—
0
0
5
47
1.07
0.09
1.2
1.2
—
—
—
0
0
7
67
1.05
0.08
1.3
1.5
—
—
—
0
0
6
73
0.81
0.08
1.3
1.3
—
—
—
0
0
59
602
0.90
0.07
5.6
4.4
2.75
2.82
mmol/l
0.32
54
564
57
563
1.05
0.01
5.3
4.0
5.99
5.95
mmol/l
0.09
51
522
23
236
0.96
0.00
3.3
2.6
—
—
—
0
0
8
84
0.95
-0.00
1.3
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
200.87
—
0
9
0
5
0.00
-0.00
0.0
3.0
—
2.30
—
0
5
5
56
0.89
-0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
20.72
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
1.19
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
925.20
—
0
5

Mortality – FinRegistry

Association

Association between endpoint L12_SUNBURN and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_SUNBURN.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: L12_SUNBURN – Sunburn

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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