Infectious mononucleosis

AB1_EBV

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 B27
  • Hospital discharge: ICD-10 B27
  • Hospital discharge: ICD-9 07[5]
  • Hospital discharge: ICD-8 07[5]
  • Cause of death: ICD-10 B27
  • Cause of death: ICD-9 07[5]
  • Cause of death: ICD-8 07[5]

3 out of 7 registries used, show all original rules.

4053

4. Check minimum number of events

None

4053

5. Include endpoints

None

4053

6. Filter based on genotype QC (FinnGen only)

3935

Control definitions (FinnGen only)

Control exclude
AB1_OTHER_VIRAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 47049 23385 23582
Only index persons 45510 22770 22740
Unadjusted period prevalence (%)
Whole population 0.66 0.67 0.66
Only index persons 0.85 0.84 0.87
Median age at first event (years)
Whole population 17.86 17.23 18.46
Only index persons 17.91 17.29 18.54

-FinnGen-

Key figures

All Female Male
Number of individuals 3935 2550 1385
Unadjusted period prevalence (%) 0.81 0.90 0.63
Median age at first event (years) 18.72 18.07 19.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4053
Matched controls
40530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B27.9
ICD-10 Finland
Infectious mononucleosis, unspecified
+∞
307.7
957
*
B27.0
ICD-10 Finland
Gammaherpesviral mononucleosis
+∞
307.7
1646
*
0750X
ICD-9 Finland
Infectious mononucleosis[MONONUCLEOSIS INFECTIOSA SINE COMPLICATIONE]
+∞
307.7
355
*
B27
ICD-10 Finland
Infectious mononucleosis
+∞
307.7
345
*
07501
ICD-8 Finland
Infectious mononucleosis, Angina monocytotica
+∞
307.7
425
*
07509
ICD-8 Finland
Infectious mononucleosis, Unspecified
+∞
173.2
165
*
0750A
ICD-9 Finland
Infectious mononucleosis[MONONUCLEOSIS INFECTIOSA CUM COMPLICATIONE]
+∞
159.4
152
*
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
3.2
143.2
666
2363
07507
ICD-8 Finland
Infectious mononucleosis, Cum alia complicatione
+∞
100.4
96
*
07508
ICD-8 Finland
Infectious mononucleosis, Suspecta
+∞
97.3
93
*
B34.9
ICD-10 Finland
Viral infection, unspecified
5.5
92.2
181
339
B27.8
ICD-10 Finland
Other infectious mononucleosis
+∞
87.8
84
*
R50.9
ICD-10 Finland
Fever, unspecified
2.2
74.8
713
3524
B27.1
ICD-10 Finland
Cytomegaloviral mononucleosis
+∞
70.0
67
*
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
2.3
61.2
513
2389
J36
ICD-10 Finland
Peritonsillar abscess
3.0
60.9
277
953
EMB10
NOMESCO Finland
Tonsillectomy
2.2
52.1
492
2399
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
44.5
989
6383
J03.0
ICD-10 Finland
Streptococcal tonsillitis
2.3
41.7
327
1471
J35.0
ICD-10 Finland
Chronic tonsillitis
2.1
39.0
403
2026
J01AA02
ATC
doxycycline; systemic
1.5
32.1
2396
19968
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
31.8
2581
21855
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
31.2
1121
8034
N02AX02
ATC
tramadol; systemic, rectal
1.5
29.3
1144
8325
J01DB01
ATC
cefalexin; oral
1.6
29.0
3243
29046
R21
ICPC
Throat symptom/complaint
1.5
28.6
1373
10416
H02AB06
ATC
prednisolone; systemic
1.5
28.5
1436
10993
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
28.3
1488
11482
R03AC02
ATC
salbutamol; inhalant
1.4
27.1
2087
17244
J01FA10
ATC
azithromycin; systemic
1.4
26.8
2556
21946
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
26.1
458
2730
A03
ICPC
Fever
1.5
25.8
948
6781
J01FF01
ATC
clindamycin; systemic
1.5
25.4
832
5800
A75
ICPC
Infectious mononucleosis
25.2
25.2
35
14
N02BE01
ATC
paracetamol; systemic, rectal
1.5
23.1
3172
28681
J02
ICD-10 Finland
Acute pharyngitis
1.9
23.0
291
1565
R07.0
ICD-10 Finland
Pain in throat
1.8
22.8
382
2242
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
21.8
2879
25657
J01FA06
ATC
roxithromycin; oral
1.4
21.8
1142
8712
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
20.8
1081
8217
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
20.6
1054
7987
R06AE07
ATC
cetirizine; oral
1.4
20.3
1752
14491
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
20.2
1465
11782
A02BC02
ATC
pantoprazole; systemic
1.4
20.0
1939
16318
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
19.4
586
3992
J01DA01
ATC
[U] cefalexin
1.4
19.3
2092
17872
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
19.1
528
3527
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
18.8
817
5994
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
18.4
269
1516
J03
ICD-10 Finland
Acute tonsillitis
2.0
18.0
208
1084
07997
ICD-8 Finland
Other viral diseases, Viroses suspectae
+∞
17.7
17
*
R01AD09
ATC
mometasone; nasal
1.3
17.5
1733
14529
03400
ICD-8 Finland
Streptococcal sore throat and scarlet fever, Streptococcal sore throat
6.4
17.1
28
44
R51.80
ICD-10 Finland
Headache
1.5
16.4
679
4922
R01AD12
ATC
fluticasone furoate; nasal
1.3
16.1
1351
11014
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
15.9
1305
10598
07999
ICD-8 Finland
Other viral diseases, Viral infection, unspecified
+∞
15.6
15
*
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
15.4
3595
33964
J01FA09
ATC
clarithromycin; systemic
1.4
15.4
1075
8515
P01AB01
ATC
metronidazole; oral, rectal
1.3
15.3
1237
10015
J01MA12
ATC
levofloxacin; systemic
1.6
15.3
376
2439
R01AD08
ATC
fluticasone; nasal
1.4
14.9
1010
7953
R01AD58
ATC
fluticasone, combinations; nasal
1.3
14.5
1064
8473
J01MA02
ATC
ciprofloxacin; systemic
1.4
14.0
945
7425
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
13.7
569
4117
H02AB04
ATC
methylprednisolone; systemic
1.6
12.9
328
2144
M03BX02
ATC
tizanidine; oral
1.3
12.6
2019
17759
ZXD05
NOMESCO Finland
Urgent procedure
1.3
12.6
965
7712
07502
ICD-8 Finland
Infectious mononucleosis, cum meningoencephalitidie
+∞
12.5
12
*
J01FA01
ATC
erythromycin; systemic
1.4
12.5
581
4287
N05BA04
ATC
oxazepam; oral
1.4
12.3
783
6082
R05
ICPC
Cough
1.3
12.2
843
6630
4452
FHL
Tonsil surgery
2.1
12.0
118
583
J02AC01
ATC
fluconazole; systemic
1.3
11.9
1267
10567
R74
ICPC
Upper respiratory infection acute
1.3
11.6
1633
14094
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
2.7
11.5
59
218
J01FA15
ATC
telithromycin; oral
1.6
11.4
249
1568
M01AH05
ATC
etoricoxib; oral
1.3
11.4
1890
16613
M01AE02
ATC
naproxen; oral, rectal
1.3
11.3
2172
19412
R03BA05
ATC
fluticasone; inhalant
1.4
11.2
623
4730
M79.6
ICD-10 Finland
Pain in limb
1.3
11.2
1280
10756
J02.0
ICD-10 Finland
Streptococcal pharyngitis
1.8
11.2
173
992
R03DC03
ATC
montelukast; oral
1.4
11.2
542
4024
SPAT1263
SPAT
Sampling
1.3
11.1
1542
13260
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
11.1
2054
18263
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
10.7
655
5048
J01DA09
ATC
[U] cefadroxil
1.3
10.7
838
6700
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
10.5
98
476
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
10.4
185
1104
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
+∞
10.4
10
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
3.3
10.4
38
116
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
2.8
10.4
49
174
E0000UV, ,
ATC
1.3
10.3
1486
12810
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
10.3
343
2377
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.8
10.2
50
181
A02BC01
ATC
omeprazole; systemic
1.3
9.8
663
5186
M01AB05
ATC
diclofenac; systemic, rectal
1.2
9.7
1977
17658
N03AX16
ATC
[U] pregabalin
1.4
9.7
503
3775
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
55.1
9.6
11
*
K76.9
ICD-10 Finland
Liver disease, unspecified
2.9
9.6
43
148
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
9.6
617
4786
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
1.9
9.6
122
660
L04AX01
ATC
azathioprine; systemic
1.8
9.6
138
776
J01CA04
ATC
amoxicillin; systemic
1.3
9.4
3393
32250
ZXA10
NOMESCO Finland
Bilateral
1.4
9.3
409
2982
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.3
546
4176
N05AH04
ATC
quetiapine; oral
1.3
9.1
705
5611
SPAT1283
SPAT
Restricted health certificate
1.3
9.1
1076
9036
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
8.3
9.0
19
23
R06AX27
ATC
desloratadine; oral
1.2
9.0
1193
10147
AA1AD
NOMESCO Finland
CT of head and brain
1.4
8.9
478
3604
C10AC01
ATC
colestyramine; oral
2.2
8.8
71
326
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.5
8.8
258
1741
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.6
8.7
207
1332
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
4.6
8.6
20
44
M25.5
ICD-10 Finland
Pain in joint
1.3
8.4
1015
8531
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.4
8.3
343
2474
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.2
501
3851
9981A
ICD-9 Finland
Other complications of procedures, not elsewhere classified, Haemorrhage or haematoma complicating a procedure
4.4
8.1
20
46
B17.8
ICD-10 Finland
Other specified acute viral hepatitis
22.1
8.0
11
5
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.7
8.0
133
782
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.6
8.0
197
1280
N30
ICD-10 Finland
Cystitis
1.5
8.0
285
2001
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
7.9
333
2409
A02BC05
ATC
esomeprazole; systemic
1.2
7.9
993
8381
J01MA14
ATC
moxifloxacin; systemic
1.6
7.9
182
1166
C01CA24
ATC
epinephrine; parenteral
1.5
7.8
253
1743
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.2
7.8
942
7910
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
7.8
747
6105
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
7.8
751
6143
F43.1
ICD-10 Finland
Post-traumatic stress disorder
1.6
7.7
154
951
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.5
7.7
257
1781
B33.2
ICD-10 Finland
Viral carditis
45.1
7.7
9
*
46309
ICD-8 Finland
Acute tonsillitis, Unspecified
2.2
7.7
63
292
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.7
592
4706
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
7.6
659
5313
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
7.6
525
4106
R03BA02
ATC
budesonide; inhalant
1.3
7.6
537
4214
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.6
1106
9471
SPAT1254
SPAT
Administration of medicine
1.3
7.6
515
4020
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
7.5
511
3989
R02AD02
ATC
lidocaine; local oral
2.0
7.5
72
355
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
7.4
314
2276
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
3.1
7.4
29
93
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
1.6
7.4
181
1176
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
7.3
526
4138
R02
ICPC
Shortness of breath/dyspnoea
1.4
7.3
324
2366
T78.4
ICD-10 Finland
Allergy, unspecified
1.6
7.3
187
1226
127
Kela drug reimbursment
Transplant complication
2.5
7.3
44
178
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.3
7.3
432
3306
0785A
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Cytomegaloviral disease[MONONUCLEOSIS INFECTIOSA CYTOMEGALICA]
+∞
7.3
7
*
ZXE00
NOMESCO Finland
One hour or less
1.2
7.2
1154
9969
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
7.2
451
3479
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.4
7.2
262
1849
UJF32
NOMESCO Finland
Coloscopy
1.3
7.2
467
3625
J03.8
ICD-10 Finland
Acute tonsillitis due to other specified organisms
3.1
7.1
29
95
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.7
7.1
129
777
0340A
ICD-9 Finland
Streptococcal sore throat and scarlatina, Streptococcal sore throat[TONSILLITIS STREPTOCOCCICA,STREPTOC BETAHAEMOLYT-A]
3.3
7.1
25
75
ZX120
NOMESCO Finland
Intravenous
1.5
7.1
200
1341
E000001, ,
ATC
1.3
7.1
710
5829
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
7.0
605
4874
H02AB07
ATC
prednisone; oral
1.4
7.0
265
1883
WYA10
NOMESCO Finland
Emergency care or similar visit
1.4
7.0
283
2036
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.5
7.0
245
1717
TAB00
NOMESCO Finland
Lumbar puncture
1.6
6.9
137
845
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
6.9
768
6384
J04.0
ICD-10 Finland
Acute laryngitis
1.5
6.8
178
1176
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
6.7
296
2160
R05
ICD-10 Finland
Cough
1.3
6.7
603
4888
A87.9
ICD-10 Finland
Viral meningitis, unspecified
2.6
6.6
35
133
M54.5
ICD-10 Finland
Low back pain
1.2
6.6
1165
10143
R11
ICD-10 Finland
Nausea and vomiting
1.4
6.6
291
2124
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.3
6.6
601
4875
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.7
6.5
116
696
4740A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Chronic tonsillitis
1.8
6.5
91
510
XW000
NOMESCO Finland
Bone marrow biopsy
2.0
6.5
64
319
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.2
6.5
904
7687
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
6.5
143
908
N06AX26
ATC
vortioxetine; oral
1.4
6.5
317
2357
G35
ICD-10 Finland
Multiple sclerosis
2.0
6.4
62
307
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.1
6.4
54
254
D70.89
ICD-10 Finland
Neutropenic splenomegaly
2.7
6.4
33
124
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.3
6.4
528
4233
SPAT1260
SPAT
Consultation of another employee
1.3
6.4
516
4125
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
6.3
1140
9941
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
6.3
704
5848
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.5
6.3
198
1360
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
2.2
6.3
47
211
J35.1
ICD-10 Finland
Hypertrophy of tonsils
1.6
6.2
124
767
S18
ICPC
Laceration/cut
1.2
6.2
1177
10309
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
6.2
630
5176
M79.1
ICD-10 Finland
Myalgia
1.3
6.1
484
3854
A07EA06
ATC
budesonide; oral, local oral
1.7
6.1
111
672
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
6.0
581
4742

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
764
2087
4.28
252.04
1.4
1.3
—
—
—
0
0
304
977
3.28
75.25
1.3
1.3
188.39
235.83
u/ml
2.17
185
596
1988
15363
1.58
42.94
6.1
5.8
31.91
30.18
%
8.80
1874
14607
1898
14573
1.57
41.74
6.4
6.1
7.98
8.06
%
0.63
1785
13792
1889
14515
1.56
41.22
6.8
6.3
—
—
—
0
0
1877
14470
1.55
39.91
6.1
5.9
2.59
2.78
%
3.44
1763
13671
1947
15156
1.55
39.46
5.8
5.7
53.95
55.86
%
9.38
1838
14404
1802
13911
1.53
37.15
6.2
6.0
0.66
0.66
%
0.06
1684
13085
2176
17565
1.52
35.85
8.1
8.3
3.88
3.98
e9/l
1.34
1928
15430
1675
12822
1.52
35.35
6.1
5.1
11.23
10.44
umol/l
1.86
1560
12028
2029
16174
1.51
35.26
6.0
5.8
2.15
2.02
e9/l
2.89
1854
14636
834
5476
1.66
33.95
3.8
3.7
—
—
—
0
0
1997
15961
1.50
33.64
6.2
6.2
0.17
0.18
e9/l
2.12
1801
14282
2477
20706
1.50
33.33
7.3
6.3
76.52
73.10
u/l
3.47
2361
19551
1932
15407
1.49
32.47
6.0
5.9
0.56
0.54
e9/l
2.11
1725
13601
210
866
2.50
32.39
1.3
1.4
—
—
—
0
0
1932
15417
1.48
32.30
6.0
5.9
0.04
0.04
e9/l
1.59
1721
13591
210
870
2.49
32.07
1.3
1.4
31.14
23.19
u/ml
—
10
16
197
819
2.48
29.86
1.3
1.4
116.74
110.18
u/ml
0.08
31
153
3593
32995
1.78
29.56
11.9
9.4
20.43
20.19
mg/l
0.18
2946
24776
1126
8205
1.52
28.52
2.5
2.4
54.47
56.45
u/l
0.82
1047
7634
965
6949
1.51
25.36
1.6
1.5
—
—
—
0
0
2524
21730
1.43
25.24
3.8
3.5
8.56
8.27
mm/h
0.64
2381
20366
372
2171
1.79
22.67
4.4
4.4
0.59
0.85
%
1.47
154
599
358
2085
1.79
21.96
4.5
4.5
0.08
0.13
%
0.54
139
512
394
2361
1.74
21.89
2.8
2.5
10.90
10.48
g/l
1.42
362
2165
344
2005
1.78
21.03
4.3
4.2
0.34
0.58
%
2.09
135
511
1704
14004
1.37
20.68
9.0
7.8
0.00
0.00
e9/l
0.36
1403
11519
3605
33728
1.62
20.27
11.4
9.5
70.69
70.38
umol/l
0.35
3605
33717
3315
30531
1.47
19.26
10.5
9.1
3.90
3.90
mmol/l
0.20
3224
29482
734
5258
1.48
19.12
2.6
2.3
7.44
8.12
e6/l
0.53
651
4669
3305
30449
1.46
18.90
10.5
9.1
139.40
139.54
mmol/l
4.07
3226
29490
80
268
3.03
18.49
1.3
1.1
—
—
—
0
0
3636
34234
1.60
18.18
9.2
7.6
31.59
27.07
u/l
9.70
3557
33218
2656
23667
1.35
17.84
3.1
2.8
39.26
36.16
u/l
1.79
2553
22703
304
1794
1.75
17.76
1.8
1.7
1.51
1.25
g/l
1.24
279
1673
1009
7763
1.40
17.65
3.0
2.7
75.14
113.69
e6/l
0.36
781
5738
330
2004
1.70
17.39
4.5
4.5
0.02
0.26
%
0.73
116
428
940
7174
1.40
17.17
2.8
2.6
—
—
—
0
0
2316
20317
1.33
16.72
4.2
3.6
1219.85
976.42
e6/l
0.09
33
212
1154
9149
1.37
16.63
6.5
6.8
1.09
1.09
inr
0.08
447
3114
80
285
2.84
16.60
3.9
3.0
1.26
1.22
%
0.05
72
262
682
4972
1.45
15.95
2.7
2.4
570.09
559.99
mosm/kgh2o
0.45
585
4279
2431
21560
1.32
15.78
4.1
3.6
—
—
—
0
0
1169
9425
1.34
14.73
3.0
2.5
—
—
—
0
0
1216
9861
1.33
14.73
3.5
3.1
29.01
68.66
e6/l
4.73
850
6296
910
7073
1.37
14.54
2.8
2.7
0.26
0.29
e6/l
0.24
676
5176
3695
35185
1.57
14.52
10.4
8.5
—
—
—
0
0
616
4522
1.43
13.72
1.4
1.4
401.39
542.52
titre
1.86
115
824
1813
15633
1.29
13.68
4.5
4.1
0.00
0.00
estimate
0.50
446
3219
1207
9861
1.32
13.66
5.1
4.6
37.14
37.35
g/l
0.71
1126
9224
1813
15661
1.29
13.39
3.3
2.9
0.00
0.00
estimate
1.34
453
3242
1820
15736
1.28
13.31
3.4
3.0
0.01
0.00
estimate
0.27
435
3121
61
214
2.88
13.09
5.1
3.6
—
—
—
0
0
1012
8147
1.32
12.52
1.5
1.4
2.11
2.10
g/l
0.14
687
5228
1030
8323
1.32
12.39
3.5
3.1
0.00
0.00
estimate
0.16
418
3136
973
7827
1.32
12.03
2.6
2.5
18.72
64.61
ng/l
0.79
418
3384
1233
10247
1.29
11.95
3.5
3.0
35.12
30.10
u/l
2.71
1184
9765
3922
38119
1.89
11.83
16.6
13.8
257.60
261.16
e9/l
3.20
3867
37257
324
2153
1.55
11.81
1.2
1.2
—
—
—
0
0
901
7194
1.32
11.70
6.3
6.6
—
—
—
0
0
3919
38089
1.87
11.69
16.6
13.8
40.78
41.05
%
0.74
3814
36391
3926
38188
1.90
11.54
16.6
13.8
6.83
6.76
e9/l
1.01
3866
37248
3924
38170
1.88
11.42
16.5
13.7
89.24
89.32
fl
0.57
3898
37744
3924
38170
1.88
11.42
16.4
13.7
29.93
29.93
pg
0.00
3898
37744
468
3376
1.44
11.37
1.6
1.6
—
—
—
0
0
3178
29743
1.32
11.35
12.8
11.4
13.91
14.35
%
1.04
3135
29192
797
6276
1.34
11.35
2.0
2.1
172.82
230.52
u/l
1.06
755
5956
3924
38180
1.87
11.26
16.5
13.8
4.61
4.61
e12/l
0.13
3865
37272
3925
38202
1.87
11.11
16.7
13.8
137.27
137.39
g/l
0.22
3899
37774
1183
9871
1.28
10.91
5.6
5.2
1.21
1.22
mmol/l
1.81
1096
9114
417
2973
1.45
10.78
3.8
3.1
—
—
—
0
0
417
2986
1.44
10.52
3.5
2.7
9.66
6.50
umol/l
1.91
356
2538
172
1007
1.74
10.40
1.8
1.6
5.23
8.82
u/ml
0.76
11
42
828
6649
1.31
10.14
2.1
1.9
0.92
0.90
mg/l
0.05
559
4671
1305
11103
1.26
10.06
6.3
5.7
1.21
1.21
mmol/l
0.62
1105
9505
79
359
2.22
9.98
1.3
1.5
—
—
—
0
0
152
870
1.78
9.95
1.2
1.4
142.73
89.48
titre
0.45
22
96
750
5967
1.32
9.79
2.4
2.2
2191.98
3078.14
umol/l
0.40
684
5471
939
7710
1.28
9.64
2.4
2.2
—
—
—
0
0
677
5330
1.32
9.50
3.1
2.6
111.37
110.71
ug/g
0.02
555
4218
114
608
1.90
9.38
1.2
1.2
—
—
—
0
0
1486
12922
1.24
9.22
3.0
2.7
6.04
5.98
ph
0.41
181
1382
811
6569
1.29
9.21
1.7
1.7
—
—
—
0
0
102
529
1.95
9.13
3.2
3.0
2.02
2.04
mmol/l
0.02
68
299
299
2071
1.48
8.97
2.7
2.6
0.23
0.23
g/l
0.05
278
1926
113
612
1.87
8.89
3.3
2.9
7.42
7.41
ph
1.59
107
555
314
2204
1.46
8.80
2.4
2.3
19.91
21.10
au/ml
0.12
38
226
115
636
1.83
8.49
1.1
1.1
—
—
—
0
0
112
616
1.84
8.42
1.1
1.1
—
—
—
0
0
632
5020
1.31
8.25
1.3
1.3
6.52
8.99
u/ml
0.75
273
2082
1754
15639
1.21
8.23
4.6
4.1
6.21
6.25
mmol/l
0.29
1611
13968
208
1359
1.56
8.23
3.0
2.9
78.66
71.77
e9/l
1.02
154
991
294
2065
1.46
8.22
1.3
1.3
40.39
41.32
au/ml
0.03
14
92
214
1409
1.55
8.18
1.7
1.7
—
—
—
0
0
801
6566
1.27
8.18
4.1
3.7
95.43
95.29
%
0.06
773
6381
3141
29714
1.25
8.05
4.6
4.3
1.72
1.97
mu/l
1.68
2991
28172
175
1109
1.60
7.90
2.6
2.4
0.34
0.18
e6/l
1.06
168
1061
1601
14189
1.21
7.88
2.3
2.1
—
—
—
0
0
110
621
1.79
7.63
3.8
3.8
55.01
55.86
%
0.26
110
621
1110
9534
1.23
7.38
1.4
1.3
1.59
1.73
u/ml
0.13
335
2603
659
5339
1.28
7.34
1.3
1.3
19.64
23.94
iu/ml
0.93
194
1543
774
6412
1.26
7.14
3.8
3.5
7.40
7.40
ph
0.17
172
1237
1959
17802
1.19
7.11
2.9
2.6
—
—
—
0
0
1340
11777
1.21
6.97
2.4
2.2
72.47
70.29
nmol/l
2.23
1260
11051
282
2030
1.42
6.93
3.6
2.9
1.81
1.66
%
1.07
258
1822
2738
25684
1.20
6.86
4.0
3.8
14.39
14.38
pmol/l
0.12
2559
23715
1264
11067
1.21
6.81
1.9
1.8
—
—
—
0
0
41
167
2.47
6.75
3.1
3.1
0.11
0.16
e9/l
1.74
41
161
683
5615
1.26
6.70
2.6
2.6
—
—
—
0
0
368
2791
1.35
6.60
1.4
1.4
—
—
—
0
0
524
4185
1.29
6.50
2.5
2.4
7687.42
6679.88
u/l
0.26
190
1680
179
1197
1.52
6.44
2.8
2.1
68.02
67.94
g/l
0.05
174
1126
196
1338
1.49
6.39
3.5
3.1
5.14
5.12
kpa
0.16
185
1284
104
610
1.72
6.39
3.6
3.5
4.07
3.91
e9/l
0.32
104
610
356
2708
1.34
6.27
2.7
3.0
—
—
—
0
0
437
3432
1.31
6.15
1.9
1.9
—
—
—
0
0
491
3916
1.29
6.15
2.4
2.5
5.58
3.66
e6/l
1.54
255
1983
142
912
1.58
6.14
1.2
1.1
—
—
—
0
0
40
169
2.38
6.12
5.2
3.1
53.65
54.79
%
0.13
34
151
142
913
1.58
6.11
1.2
1.1
—
—
—
0
0
30
110
2.74
6.10
1.2
1.1
—
—
—
0
0
30
110
2.74
6.10
1.2
1.1
—
—
—
0
0
30
110
2.74
6.10
1.2
1.1
—
—
—
0
0
193
1328
1.48
6.07
3.5
3.1
7.41
7.41
ph
0.01
30
160
79
439
1.82
5.86
2.7
2.1
17.69
17.52
%
0.10
34
212
61
312
1.97
5.82
2.8
2.7
1.16
1.26
e9/l
0.46
55
266
147
965
1.54
5.79
1.3
1.3
—
—
—
0
0
90
522
1.74
5.79
3.9
2.7
—
—
—
0
0
424
3345
1.30
5.77
2.6
2.4
29.66
29.43
s
0.38
407
3239
895
7694
1.21
5.69
2.9
2.8
2.35
2.35
mmol/l
0.27
822
7032
231
1673
1.40
5.54
3.3
3.1
1.22
1.23
mmol/l
2.20
196
1447
1855
17004
1.17
5.52
3.1
2.8
89.54
74.63
ug/l
2.14
1753
16106
175
1215
1.46
5.30
2.4
2.4
20.87
21.06
s
0.16
147
1022
155
1053
1.49
5.24
1.2
1.1
—
—
—
0
0
147
990
1.50
5.18
1.2
1.1
—
—
—
0
0
91
551
1.67
5.05
2.1
2.1
2.54
1.67
ug/l
0.31
83
497
52
266
1.97
5.01
1.1
1.1
—
—
—
0
0
380
3022
1.28
4.88
2.5
2.3
24.55
24.52
%
0.01
341
2633
455
3699
1.26
4.88
2.4
2.2
15.24
14.87
umol/l
0.39
429
3467
55
290
1.91
4.87
1.1
1.2
—
—
—
0
0
291
2236
1.32
4.83
2.9
3.4
4.69
4.69
pmol/l
0.01
259
2014
1242
11123
1.17
4.81
1.8
1.8
—
—
—
0
0
35
157
2.24
4.74
1.2
1.1
—
—
—
0
0
406
3268
1.27
4.74
1.6
1.6
1128.69
1141.58
nmol/l
0.12
333
2548
28
114
2.47
4.70
2.3
2.1
—
—
—
0
0
275
2105
1.33
4.69
1.7
2.2
4.93
5.06
e9/l
0.06
238
1830
499
4120
1.24
4.67
2.3
2.4
0.81
1.13
e6/l
1.03
264
2188
150
1039
1.46
4.64
1.9
1.9
1.19
1.17
g/l
0.33
145
993
26
103
2.53
4.62
2.2
2.1
—
—
—
0
0
412
3338
1.26
4.55
2.4
2.2
2.53
2.49
g/l
0.70
377
3101
284
2196
1.32
4.52
1.1
1.1
424.29
187.61
titre
—
7
57
39
187
2.10
4.51
1.2
1.1
—
—
—
0
0
70
409
1.72
4.47
1.0
1.1
1.48
1.45
g/l
0.25
64
371
15
44
3.42
4.46
1.0
1.2
—
—
—
0
0
319
2511
1.29
4.45
2.3
2.4
35.23
56.00
u/l
0.56
274
2164
2947
28198
1.17
4.45
3.2
3.1
5.57
5.59
mmol/l
0.50
2781
26469
468
3861
1.24
4.41
2.8
2.8
575.89
499.69
ng/l
0.07
221
2035
442
3625
1.25
4.40
3.3
2.8
843.93
661.25
ng/l
0.44
343
2818
130
888
1.48
4.34
2.3
1.8
—
—
—
0
0
39
191
2.05
4.28
1.1
1.1
—
—
—
0
0
47
247
1.91
4.24
2.1
2.2
13.06
12.34
%
0.28
47
242
26
108
2.42
4.21
2.2
2.1
8.12
8.72
%
0.14
26
103
1000
8887
1.17
4.18
1.7
1.6
97.10
97.99
pmol/l
0.28
598
4996
35
166
2.12
4.18
2.6
2.3
7.87
9.80
mg/l
1.19
29
139
48
256
1.89
4.16
1.1
1.1
—
—
—
0
0
324
2581
1.28
4.14
1.4
1.3
201.73
260.89
u/ml
0.98
295
2389
35
167
2.11
4.12
1.3
1.4
—
—
—
0
0
38
188
2.03
4.08
3.2
2.8
1.28
1.89
g/24h
0.95
27
116
106
704
1.52
4.07
1.2
1.1
16.76
11.83
au/ml
—
9
56
371
3010
1.26
4.07
2.1
2.0
364.70
385.79
nmol/l
1.37
338
2768
114
771
1.49
4.02
1.6
1.6
1066.46
5672.68
e6/l
0.47
94
623
114
771
1.49
4.02
1.6
1.5
32.13
18.20
e6/l
0.52
92
593
424
3497
1.24
4.02
4.6
3.8
0.83
0.83
mmol/l
0.00
398
3315
281
2207
1.29
4.01
1.4
1.4
—
—
—
0
0
47
253
1.87
3.97
2.1
2.2
73.19
74.89
%
0.33
47
243
145
1031
1.42
3.95
3.2
2.9
3.62
3.58
g/l
0.11
132
981
242
1871
1.31
3.89
4.7
4.4
1.49
1.77
mmol/l
0.85
213
1539
243
1886
1.31
3.81
4.5
4.4
5.89
5.89
kpa
0.01
236
1827
24
101
2.38
3.81
7.6
8.3
97.32
73.47
mg/l
0.73
19
76
179
1331
1.36
3.76
1.2
1.3
0.21
0.83
u/ml
—
8
99
1088
9805
1.15
3.71
1.8
1.8
—
—
—
0
0
21
85
2.48
3.62
1.4
1.7
—
—
—
0
0
124
874
1.43
3.58
1.4
1.5
432.86
446.17
mg/l
0.11
116
828
106
725
1.47
3.58
1.5
1.6
—
—
—
0
0
122
858
1.44
3.57
3.2
3.2
1.35
1.45
%
0.45
122
852
135
968
1.41
3.55
3.6
3.3
—
—
—
0
0
547
4688
1.19
3.52
3.3
3.1
2.25
1.65
ug/l
0.90
504
4320
536
4588
1.19
3.50
1.6
1.5
15948683.83
37934018.38
pmol/l
0.63
464
4036
226
1763
1.30
3.44
7.9
8.6
—
—
—
0
0
215
1666
1.31
3.44
2.5
3.0
—
—
—
0
0
384
3195
1.22
3.37
1.2
1.2
—
—
—
0
0
2604
24900
1.13
3.32
3.8
3.8
36.74
37.20
mmol/mol
2.01
2474
23680
21
89
2.37
3.31
1.3
1.3
—
—
—
0
0
333
2736
1.24
3.30
2.2
2.3
0.65
0.64
ug/l
0.16
160
1366
54
322
1.69
3.30
1.3
1.3
—
—
—
0
0
203
1575
1.30
3.24
3.9
3.8
4.88
4.77
kpa
0.35
197
1518
415
3497
1.21
3.22
2.3
2.5
2.41
2.41
mmol/l
0.03
370
3067
385
3221
1.22
3.21
1.2
1.2
—
—
—
0
0
173
1317
1.33
3.16
1.7
1.7
—
—
—
0
0
224
1767
1.28
3.16
6.7
7.1
1.41
1.37
mmol/l
0.15
217
1724
41
229
1.80
3.15
1.8
1.9
—
—
—
0
0
38
208
1.83
3.12
2.2
1.6
—
—
—
0
0
3060
29601
1.14
3.11
3.2
3.2
4.67
4.69
mmol/l
0.69
2935
28359
13
41
3.18
3.05
3.2
3.3
—
—
—
0
0
819
7329
1.15
3.04
3.4
3.4
9.14
8.78
mmol/l
0.90
720
6567
43
247
1.75
3.03
2.9
2.8
0.21
0.20
e9/l
0.24
37
205
45
262
1.73
3.02
3.1
2.8
602.78
695.03
e6/l
0.95
45
254
108
770
1.41
2.99
1.4
1.4
3.39
3.55
mmol/l
1.22
98
718
158
1201
1.33
2.94
2.2
2.4
4.24
5.22
umol/l
1.28
112
898
2921
28213
1.13
2.92
3.0
2.9
1.29
1.25
mmol/l
1.69
2790
26925
51
312
1.64
2.87
4.1
2.8
15.24
2.87
ratio
—
9
39
16
64
2.51
2.87
1.0
1.2
—
—
—
0
0
44
259
1.71
2.86
1.3
1.2
—
—
—
0
0
109
786
1.40
2.84
1.2
1.2
—
—
—
0
0
1564
14617
1.11
2.82
2.6
2.4
—
—
—
0
0
45
268
1.69
2.81
1.2
1.3
—
—
—
0
0
89
623
1.44
2.75
2.6
2.6
—
—
—
0
0
98
700
1.41
2.71
1.1
1.1
2.71
2.67
u/ml
0.01
57
373
215
1727
1.26
2.66
10.3
8.2
7.27
7.05
mmol/l
0.25
208
1658
51
319
1.61
2.66
4.1
2.8
79.33
71.67
mg/l
0.08
40
260
51
319
1.61
2.66
4.1
2.8
30.41
30.03
mg/l
0.03
39
258
3033
29419
1.12
2.64
3.2
3.1
1.42
1.44
mmol/l
1.75
2897
28123
110
806
1.37
2.63
2.0
2.0
1.35
1.31
g/l
0.15
94
712
13
49
2.66
2.62
1.2
1.8
—
—
—
0
0
40
236
1.70
2.61
6.0
6.6
9.42
9.88
mg/l
0.30
35
214
42
252
1.67
2.58
1.1
1.1
6.06
6.21
iu/ml
0.02
14
57
3062
29738
1.12
2.54
3.3
3.3
2.83
2.85
mmol/l
0.47
2921
28323
1324
12320
1.11
2.53
1.8
1.7
—
—
—
0
0
49
309
1.59
2.49
1.0
1.0
—
—
—
0
0
33
187
1.77
2.48
1.7
1.5
—
—
—
0
0
8
21
3.81
2.46
1.0
1.7
—
—
—
0
0
376
3228
1.18
2.42
1.2
1.2
66.81
156.25
iu/ml
8.32
115
1205
39
234
1.67
2.41
1.2
1.2
—
—
—
0
0
762
6889
1.13
2.40
3.1
2.9
—
—
—
0
0
7
17
4.12
2.36
1.4
1.5
—
—
—
0
0
361
3096
1.18
2.36
2.2
2.3
—
—
—
0
0
751
6800
1.13
2.31
2.3
2.1
2.71
2.66
mg/l
0.35
652
5851
31
177
1.76
2.29
3.2
4.5
11.08
11.67
%
0.37
31
177
48
308
1.57
2.29
1.2
1.3
—
—
—
0
0
6
13
4.62
2.27
2.2
4.6
—
—
—
0
0
420
3660
1.16
2.26
2.2
2.2
—
—
—
0
0
335
2866
1.18
2.26
6.5
6.1
1.07
1.06
mmol/l
0.19
319
2702
1356
12694
1.10
2.26
2.1
2.1
—
—
—
0
0
24
127
1.90
2.25
1.2
1.1
3.80
4.25
iu/ml
—
5
12
3195
31167
1.12
2.25
12.8
11.5
334.43
334.07
g/l
1.51
3175
30892
41
255
1.61
2.23
3.0
2.8
570.49
507.60
e6/l
0.45
35
205
79
565
1.41
2.23
1.3
1.3
—
—
—
0
0
96
710
1.36
2.22
3.3
2.5
—
—
—
0
0
84
609
1.39
2.20
1.2
1.3
3.59
3.80
u/ml
0.09
41
276
50
328
1.53
2.18
3.2
2.1
—
—
—
0
0
92
680
1.36
2.15
1.2
1.1
—
—
—
0
0
6
14
4.29
2.15
2.0
4.4
—
—
—
0
0
7
19
3.69
2.15
1.6
1.4
—
—
—
0
0
472
4166
1.15
2.15
1.5
1.5
—
—
—
0
0
973
8983
1.11
2.12
2.3
2.0
—
—
—
0
0
31
182
1.71
2.11
1.6
1.7
44.96
36.92
%
0.53
25
122
47
307
1.54
2.10
1.0
1.3
—
—
—
0
0
192
1569
1.23
2.10
1.1
1.1
—
—
—
0
0
39
244
1.60
2.09
4.8
2.9
—
—
—
0
0
451
3982
1.15
2.05
2.1
2.2
—
—
—
0
0
19
96
1.98
2.05
1.5
1.6
4.86
7.60
%
—
7
25
20
367
0.54
2.04
8.0
15.1
634.30
797.54
nmol/l
0.92
20
355
16
76
2.11
2.02
1.1
1.1
—
—
—
0
0
446
3945
1.15
1.98
2.1
2.2
—
—
—
0
0
7
21
3.34
1.96
1.1
1.0
—
—
—
0
0
21
374
0.56
1.95
11.4
21.9
1188.95
1382.76
nmol/l
0.43
21
361
18
91
1.98
1.95
2.1
3.2
7.43
7.43
ph
—
5
21
448
3975
1.14
1.91
2.1
2.0
—
—
—
0
0
176
1445
1.23
1.88
1.7
2.2
30.87
32.56
u/ml
0.07
169
1393
58
407
1.43
1.87
1.2
1.1
50.11
38.10
mg/l
0.73
47
326
5
12
4.17
1.82
27.4
2.8
—
—
—
0
0
115
903
1.28
1.81
2.9
3.7
0.22
0.38
g/l
1.39
67
440
57
402
1.42
1.80
1.5
1.5
—
—
—
0
0
100
773
1.30
1.78
1.3
1.3
1.99
4.33
u/ml
—
10
83
156
1274
1.23
1.77
1.1
1.1
2.77
4.69
u/ml
0.87
33
196
357
3138
1.15
1.76
1.4
1.5
—
—
—
0
0
50
346
1.45
1.75
2.0
1.4
—
—
—
0
0
438
3906
1.14
1.75
2.1
2.1
—
—
—
0
0
101
785
1.29
1.73
1.3
1.3
7.71
12.58
u/ml
0.38
16
116
153
1251
1.23
1.72
1.5
1.6
—
—
—
0
0
54
381
1.42
1.71
1.5
1.7
—
—
—
0
0
5
13
3.85
1.71
1.0
1.0
—
—
—
0
0
40
266
1.51
1.70
1.4
1.3
125.00
203.16
titre
—
8
57
39
258
1.52
1.70
1.2
1.1
1675.70
1527.39
miu/ml
0.32
39
258
201
1693
1.20
1.68
1.5
1.4
—
—
—
0
0
83
631
1.32
1.68
1.4
1.4
326.17
311.66
ug/g
0.25
42
311
69
510
1.36
1.68
2.9
2.1
135.20
135.36
g/l
0.02
55
393
528
4779
1.12
1.66
1.4
1.4
18.55
20.03
nmol/l
2.11
478
4303
89
686
1.30
1.64
6.7
4.3
—
—
—
0
0
5
14
3.57
1.61
1.2
1.0
—
—
—
0
0
28
174
1.61
1.60
2.2
1.9
—
—
—
0
0
55
395
1.40
1.60
1.1
1.1
261.33
229.99
mg/l
0.26
45
337
30
190
1.58
1.59
4.8
3.1
259.62
169.65
umol/l
0.40
13
106
233
2001
1.17
1.58
4.2
3.4
—
—
—
0
0
70
526
1.34
1.55
3.7
3.9
117.32
2471.82
u/ml
0.66
58
445
13
64
2.03
1.54
1.2
1.3
—
—
—
0
0
5
15
3.34
1.52
1.0
2.1
—
—
—
0
0
5
15
3.34
1.52
1.6
1.2
2.68
3.88
mmol/l
—
5
15
39
267
1.47
1.48
1.1
1.1
—
—
—
0
0
102
813
1.26
1.48
1.3
1.4
15.48
16.34
u/l
0.12
83
705
59
436
1.36
1.47
3.9
3.8
—
—
—
0
0
9
38
2.37
1.45
1.0
1.9
—
—
—
0
0
151
1259
1.21
1.45
2.0
2.2
4.26
7.03
ug/l
2.07
135
1117
6
22
2.73
1.43
1.0
1.0
—
—
—
0
0
26
165
1.58
1.40
1.9
3.1
—
—
—
0
0
304
2695
1.14
1.37
1.7
1.6
—
—
—
0
0
730
6788
1.09
1.37
2.2
2.0
—
—
—
0
0
289
2558
1.14
1.34
1.3
1.4
19.82
18.04
iu/l
0.49
239
2127
85
672
1.27
1.34
2.5
2.5
416.46
333.25
ug/l
0.13
76
605
111
906
1.23
1.33
1.7
2.1
3.77
4.31
iu/l
0.35
43
365
9
42
2.15
1.33
1.4
1.2
—
—
—
0
0
211
1827
1.16
1.33
3.0
3.0
—
—
—
0
0
16
90
1.78
1.32
2.4
2.0
—
—
—
0
0
55
410
1.35
1.32
2.1
2.1
—
—
—
0
0
207
1791
1.16
1.32
1.1
1.1
—
—
—
0
0
18
106
1.70
1.29
1.1
1.1
—
—
—
0
0
8
34
2.36
1.29
2.4
2.1
—
—
—
0
0
62
473
1.32
1.29
1.2
1.4
—
—
—
0
0
47
345
1.37
1.26
2.1
1.4
0.38
0.38
g/l
0.00
35
234
72
563
1.28
1.26
1.9
1.7
0.57
0.72
g/l
1.00
56
427
753
7039
1.09
1.26
3.2
3.0
1.02
1.02
kg/l
0.17
106
1027
63
484
1.31
1.25
1.3
1.6
—
—
—
0
0
14
77
1.82
1.25
1.0
1.0
—
—
—
0
0
47
346
1.36
1.24
2.1
1.4
2.84
2.96
g/l
0.23
35
237
47
346
1.36
1.24
2.1
1.4
6.70
6.44
g/l
0.21
35
238
97
791
1.23
1.20
1.1
1.1
0.04
0.40
u/ml
3.35
26
220
315
2828
1.12
1.19
1.5
1.6
333.18
303.04
mu/l
0.56
284
2540
46
341
1.35
1.17
1.7
1.6
—
—
—
0
0
121
1012
1.20
1.17
1.1
1.1
3.50
4.45
u/ml
0.36
77
525
389
3538
1.11
1.17
1.3
1.3
—
—
—
0
0
16
94
1.70
1.17
1.3
1.5
37.83
34.31
g/l
0.52
16
83
23
149
1.55
1.17
5.4
3.0
—
—
—
0
0
50
377
1.33
1.15
1.8
1.9
—
—
—
0
0
13
72
1.81
1.15
1.2
2.9
—
—
—
0
0
29
199
1.46
1.14
4.7
2.6
—
—
—
0
0
31
216
1.44
1.13
2.1
4.1
—
—
—
0
0
558
5185
1.09
1.09
4.3
4.0
11.00
11.90
mg/mmol
0.18
385
3560
110
920
1.20
1.09
1.1
1.1
5.43
7.12
u/ml
0.42
60
416
192
1683
1.15
1.08
1.3
1.4
—
—
—
0
0
11
59
1.87
1.07
1.5
1.3
—
—
—
0
0
536
4978
1.09
1.06
3.7
3.5
288.94
344.18
mg/l
0.14
377
3436
5
22
2.27
1.03
1.0
1.7
—
—
—
0
0
52
402
1.30
1.03
2.2
3.3
—
—
—
0
0
372
3403
1.10
1.03
1.2
1.2
—
—
—
0
0
7
34
2.06
1.02
1.1
1.2
—
—
—
0
0
314
2848
1.11
1.02
2.6
2.1
12.46
11.79
nmol/l
0.78
295
2623
5
23
2.18
0.98
1.2
1.3
—
—
—
0
0
268
2421
1.11
0.96
1.4
1.3
232.14
230.28
miu/ml
0.03
132
1205
22
149
1.48
0.95
1.9
2.2
30.55
28.89
%
0.23
22
144
11
62
1.78
0.94
1.1
1.1
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
—
—
—
0
0
28
200
1.40
0.93
1.1
1.1
6.92
8.64
u/ml
0.10
20
122
150
1309
1.15
0.93
3.7
4.1
5.97
44.82
ug/l
0.77
109
943
9
52
1.73
0.92
9.9
3.6
30.56
65.46
u/l
—
9
52
26
184
1.42
0.91
2.5
2.7
39.42
45.20
%
0.49
11
92
228
2049
1.12
0.90
1.4
1.5
10.07
8.00
u/l
1.44
192
1688
123
1061
1.16
0.89
3.4
2.7
102.62
116.56
ng/l
0.31
98
915
142
1239
1.15
0.89
1.3
1.3
—
—
—
0
0
8
42
1.91
0.88
18.5
6.5
—
—
—
0
0
17
111
1.53
0.87
1.4
1.2
25.17
15.44
%
—
6
9
15
95
1.58
0.87
2.8
2.9
—
—
—
0
0
8
44
1.82
0.85
1.3
1.1
—
—
—
0
0
52
415
1.26
0.84
3.1
2.8
—
—
—
0
0
188
1681
1.12
0.83
8.8
8.8
95.57
96.42
%
0.78
182
1618
6
114
0.53
0.82
1.0
1.4
19.33
36.69
mmol/l
—
6
109
107
921
1.17
0.82
2.0
2.1
—
—
—
0
0
213
1921
1.11
0.81
8.0
8.2
4.94
5.04
kpa
0.97
205
1839
213
1921
1.11
0.81
8.0
8.2
13.32
13.71
kpa
0.41
205
1841
108
932
1.16
0.80
1.6
1.6
—
—
—
0
0
32
241
1.33
0.80
1.7
1.7
46.79
48.88
%
0.11
24
167
21
147
1.43
0.80
2.1
2.2
1.03
1.47
nmol/l
1.48
14
118
14
90
1.56
0.78
3.4
2.8
—
—
—
0
0
6
34
1.77
0.76
2.3
3.1
—
—
—
0
0
25
183
1.37
0.75
1.4
1.4
6.04
6.40
u/l
0.13
20
150
70
586
1.20
0.75
2.6
2.8
21.74
23.69
mg/l
0.23
43
357
21
149
1.41
0.75
1.3
1.3
163.81
172.17
mmol/24h
0.21
21
149
287
2642
1.09
0.75
3.0
3.0
31.46
31.51
%
0.03
232
2047
9
56
1.61
0.72
2.0
1.5
—
—
—
0
0
26
194
1.34
0.71
1.4
1.2
1.53
1.47
nmol/l
0.09
21
179
5
26
1.92
0.70
1.0
1.2
—
—
—
0
0
43
531
0.81
0.69
1.3
1.3
—
—
—
0
0
39
310
1.26
0.69
3.0
3.1
40616.03
39713.17
ug/l
0.13
39
310
20
144
1.39
0.67
1.6
1.7
—
—
—
0
0
17
119
1.43
0.66
1.1
1.1
—
—
—
0
0
19
136
1.40
0.66
2.0
2.2
193.85
185.87
e6/l
0.06
13
75
5
28
1.79
0.66
2.6
2.1
94.00
129.93
ng/l
—
5
28
22
162
1.36
0.66
1.9
2.5
12.91
9.64
%
0.35
22
156
80
688
1.17
0.66
2.3
2.0
—
—
—
0
0
34
268
1.27
0.65
1.1
1.1
328.50
286.10
mg/l
1.14
28
246
120
1065
1.13
0.64
1.1
1.1
—
—
—
0
0
64
542
1.18
0.64
1.9
1.5
—
—
—
0
0
33
260
1.27
0.63
1.7
1.6
5.60
5.77
mmol/l
0.17
25
212
29
225
1.29
0.63
6.5
6.0
—
—
—
0
0
29
225
1.29
0.63
3.2
3.0
—
—
—
0
0
152
1371
1.11
0.63
4.1
4.2
67.93
71.07
ng/l
0.29
141
1259
31
244
1.27
0.61
3.8
3.6
7.79
8.70
mg/l
0.45
25
200
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
18.22
—
0
14
209
1921
1.09
0.60
8.2
8.2
0.90
0.64
mmol/l
0.45
158
1454
0
21
0.00
0.60
0.0
1.0
—
0.19
—
0
10
40
326
1.23
0.59
1.1
1.0
—
—
—
0
0
210
1933
1.09
0.59
1.2
1.2
—
—
—
0
0
27
210
1.29
0.58
1.3
1.2
1.54
1.52
g/l
0.15
27
210
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
0.56
—
0
5
25
193
1.30
0.57
1.2
1.2
—
—
—
0
0
480
4562
1.06
0.57
2.0
2.0
—
—
—
0
0
32
397
0.80
0.56
1.1
1.1
—
—
—
0
0
8
55
1.46
0.56
1.4
1.1
—
—
—
0
0
18
133
1.35
0.55
2.6
2.0
—
—
—
0
0
6
38
1.58
0.54
1.2
1.2
—
—
—
0
0
12
82
1.46
0.54
1.3
1.5
—
—
—
0
0
196
1809
1.09
0.53
2.7
2.4
—
—
—
0
0
22
172
1.28
0.48
1.0
1.1
—
—
—
0
0
7
47
1.49
0.47
11.1
4.8
—
—
—
0
0
34
281
1.21
0.47
1.1
1.1
1.06
1.05
ratio
0.19
12
109
7
48
1.46
0.46
1.1
1.1
—
—
—
0
0
22
276
0.80
0.45
3.6
3.2
—
—
—
0
0
68
600
1.14
0.45
1.1
1.1
117.67
2303.07
iu/ml
0.74
25
176
100
904
1.11
0.44
9.8
10.4
23.95
24.03
mmol/l
0.09
95
884
15
112
1.34
0.44
1.3
1.4
—
—
—
0
0
128
1173
1.09
0.44
1.1
1.1
1.37
1.42
u/ml
0.04
62
544
17
130
1.31
0.43
4.8
3.1
18.76
42.16
u/ml
1.16
17
130
5
31
1.61
0.43
5.8
5.0
—
—
—
0
0
5
31
1.61
0.43
1.0
1.3
1.58
1.11
mmol/l
—
5
31
327
3108
1.06
0.42
1.2
1.3
—
—
—
0
0
17
131
1.30
0.42
2.1
2.4
1986.00
2191.25
ml
0.48
17
125
32
267
1.20
0.42
1.3
1.3
2.44
2.74
u/ml
0.08
17
124
24
194
1.24
0.42
1.2
1.2
—
—
—
0
0
10
70
1.43
0.41
1.6
1.5
—
—
—
0
0
70
624
1.12
0.40
4.0
6.6
1.30
1.17
mmol/l
0.63
64
549
0
17
0.00
0.40
0.0
1.1
—
32.38
—
0
17
0
18
0.00
0.40
0.0
1.2
—
69.71
—
0
18
46
399
1.15
0.39
1.9
2.0
6.17
5.27
mmol/24h
0.74
40
367
5
35
1.43
0.39
3.2
3.5
—
5.23
—
0
8
36
420
0.86
0.38
2.9
3.6
4.92
72.00
u/ml
1.02
36
412
5
36
1.39
0.38
1.0
1.3
—
22.78
—
0
12
5
36
1.39
0.38
1.0
1.3
—
27.50
—
0
10
9
67
1.34
0.38
3.4
4.9
24.14
24.88
mmol/l
—
9
62
149
1387
1.08
0.37
1.1
1.1
2.27
2.81
u/ml
0.20
85
743
22
179
1.23
0.37
1.0
1.1
0.16
5.02
nmol/l
—
6
33
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
9
69
1.31
0.37
1.9
1.8
—
—
—
0
0
13
99
1.31
0.35
1.3
1.2
—
—
—
0
0
13
99
1.31
0.35
1.2
1.2
—
—
—
0
0
114
1054
1.08
0.35
2.7
2.4
—
—
—
0
0
43
376
1.15
0.35
1.0
1.1
0.30
2.08
u/ml
1.37
13
138
22
181
1.22
0.34
1.0
1.1
—
—
—
0
0
129
1200
1.08
0.34
1.1
1.1
1.10
2.39
u/ml
3.26
76
641
26
218
1.19
0.34
1.3
1.3
—
—
—
0
0
19
154
1.23
0.33
3.1
2.8
—
—
—
0
0
6
45
1.33
0.33
1.0
1.2
—
—
—
0
0
15
118
1.27
0.33
1.5
1.7
—
—
—
0
0
115
1067
1.08
0.33
1.4
1.5
0.29
0.46
nmol/l
3.87
92
876
13
166
0.78
0.33
6.2
7.2
—
—
—
0
0
132
1234
1.07
0.31
1.1
1.1
9.20
7.52
u/ml
0.44
77
706
12
92
1.31
0.31
1.1
2.6
—
—
—
0
0
7
54
1.30
0.30
1.3
1.1
—
6.00
—
0
6
91
842
1.08
0.29
7.7
7.1
—
—
—
0
0
21
176
1.19
0.28
1.6
2.5
18.29
183.21
ug/l
0.74
21
157
16
130
1.23
0.28
1.2
1.2
—
—
—
0
0
20
168
1.19
0.27
1.2
1.2
—
—
—
0
0
26
224
1.16
0.27
1.4
1.2
—
—
—
0
0
30
341
0.88
0.25
3.5
4.2
147.17
73.71
u/ml
—
9
106
14
170
0.82
0.25
1.5
1.2
—
—
—
0
0
13
105
1.24
0.24
1.0
1.1
—
—
—
0
0
13
105
1.24
0.24
1.0
1.0
—
—
—
0
0
9
76
1.18
0.24
6.2
5.7
25.30
42.81
g/mol
—
9
69
220
2291
0.96
0.24
1.5
1.5
—
—
—
0
0
19
161
1.18
0.24
1.1
1.2
—
—
—
0
0
13
106
1.23
0.23
1.2
1.1
—
—
—
0
0
44
400
1.10
0.22
4.2
2.5
—
—
—
0
0
639
6521
0.98
0.22
1.6
1.6
1.43
1.39
mmol/l
0.29
550
5783
26
294
0.88
0.21
3.2
2.7
6.65
6.97
mmol/l
0.35
26
289
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
53
490
1.08
0.20
8.8
4.2
3.73
3.80
mmol/l
0.91
53
484
228
2359
0.96
0.20
1.6
1.5
—
—
—
0
0
20
174
1.15
0.19
3.9
2.9
97.84
48.44
mg/l
0.53
14
124
40
365
1.10
0.19
1.5
1.6
—
—
—
0
0
222
2296
0.96
0.19
1.6
1.5
—
—
—
0
0
14
164
0.85
0.18
1.5
2.1
—
—
—
0
0
7
59
1.19
0.18
1.0
1.4
55.09
47.09
%
—
7
54
105
1000
1.05
0.18
6.6
5.8
—
—
—
0
0
68
723
0.94
0.17
2.0
1.8
12.96
13.01
%
0.21
68
717
113
1079
1.05
0.17
12.2
9.9
93.33
94.36
%
0.58
113
1073
10
82
1.22
0.17
1.2
1.5
—
—
—
0
0
21
186
1.13
0.17
1.2
1.4
75.00
79.05
%
—
5
20
10
120
0.83
0.16
1.5
1.1
—
—
—
0
0
72
680
1.06
0.16
1.8
1.8
—
—
—
0
0
8
70
1.14
0.16
1.6
1.4
—
—
—
0
0
8
71
1.13
0.16
2.1
1.3
145.61
120.15
nmol/l
—
8
53
140
1454
0.96
0.16
1.2
1.2
—
—
—
0
0
74
701
1.06
0.15
1.2
1.2
14.37
41.47
u/ml
—
7
58
29
318
0.91
0.15
1.3
1.5
—
—
—
0
0
12
103
1.17
0.13
1.1
1.7
—
—
—
0
0
52
551
0.94
0.13
1.2
1.4
37.44
32.08
nmol/l
0.40
47
505
15
132
1.14
0.13
1.1
1.2
—
—
—
0
0
13
113
1.15
0.13
1.1
1.2
0.15
0.86
u/ml
1.66
13
113
23
209
1.10
0.13
1.1
1.1
—
—
—
0
0
22
242
0.91
0.13
1.3
1.5
105.81
72.56
mmol/l
1.60
16
203
25
229
1.09
0.12
2.1
2.0
—
—
—
0
0
13
114
1.14
0.11
4.4
4.4
—
—
—
0
0
43
456
0.94
0.11
1.3
1.7
16321.88
12308.69
e6/l
0.35
34
341
39
368
1.06
0.10
1.6
1.5
1.25
1.38
promille
0.22
28
276
51
534
0.95
0.09
1.6
2.5
0.92
0.84
nmol/l
0.53
43
456
6
57
1.05
0.08
1.2
1.0
—
—
—
0
0
5
63
0.79
0.08
1.4
1.2
—
—
—
0
0
16
147
1.09
0.07
2.8
1.9
1.67
2.24
u/field
—
6
86
22
234
0.94
0.06
1.1
1.0
6.35
16.65
u/ml
2.96
14
136
38
364
1.04
0.06
1.1
1.0
0.76
1.58
u/ml
—
10
100
560
5561
1.01
0.05
1.3
1.3
—
—
—
0
0
382
3788
1.01
0.05
1.4
1.4
—
—
—
0
0
40
387
1.03
0.04
1.1
1.1
2.25
2.56
u/ml
—
10
108
35
339
1.03
0.03
1.2
1.4
191.81
205.82
pmol/l
0.17
35
339
14
149
0.94
0.03
1.1
1.1
—
—
—
0
0
136
1347
1.01
0.02
1.3
1.3
3.61
3.98
ug/l
0.30
130
1285
55
540
1.02
0.02
1.1
1.1
—
—
—
0
0
27
263
1.03
0.01
3.4
6.3
6.34
6.77
mmol/l
0.46
21
213
94
948
0.99
0.01
10.8
11.1
—
—
—
0
0
33
324
1.02
0.00
1.0
1.0
—
—
—
0
0
32
326
0.98
0.00
2.9
2.6
1.25
1.46
mmol/l
1.17
32
316
109
1084
1.01
0.00
12.6
9.8
0.70
0.69
%
0.20
109
1075
289
2896
1.00
0.00
1.5
1.4
—
—
—
0
0
16
158
1.01
0.00
1.1
1.1
—
—
—
0
0
22
218
1.01
0.00
1.2
1.3
82.27
71.83
umol/l
1.35
22
218
13
131
0.99
0.00
2.1
1.5
—
—
—
0
0
14
136
1.03
0.00
1.2
1.4
127.43
92.14
nmol/24h
0.45
14
136
13
134
0.97
0.00
2.2
2.1
15.40
15.09
umol/l
0.04
13
134
45
453
0.99
0.00
2.4
2.6
192.19
115.58
ug/min
0.39
28
307
13
133
0.98
0.00
1.6
1.5
135.26
134.35
nmol/l
0.04
13
133
0
9
0.00
0.00
0.0
1.3
—
2.39
—
0
9
5
53
0.94
0.00
2.0
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
8
89
0.90
-0.00
1.4
1.1
—
—
—
0
0
6
60
1.00
-0.00
1.3
1.7
2.27
1.50
mg/l
—
6
52
5
57
0.88
-0.00
2.0
1.5
—
—
—
0
0
5
56
0.89
-0.00
2.2
1.4
—
—
—
0
0
6
65
0.92
-0.00
1.3
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
80.38
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
273.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.4
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
59
0.85
-0.00
2.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_EBV and mortality.

Females

Parameter HR [95% CI] p-value
AB1_EBV 1.492 [1.12, 1.99] 0.006
Birth year 1.0 [0.99, 1.01] 0.947

During the follow-up period (1.1.1998 — 31.12.2019), 118 out of 16191 females with AB1_EBV died.

Males

Parameter HR [95% CI] p-value
AB1_EBV 1.411 [1.2, 1.65] < 0.001
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 14786 males with AB1_EBV died.

Mortality risk

Mortality risk for people of age

years, who have AB1_EBV.

N-year risk Females Males
1 0.208% 0.257%
5 1.039% 1.587%
10 2.769% 4.122%
15 5.219% 7.827%
20 8.95% 12.79%

Relationships between endpoints

Index endpoint: AB1_EBV – Infectious mononucleosis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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