Impacted cerumen

H8_CERUMEN

auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H61.2
  • Hospital discharge: ICD-9 3804
  • Hospital discharge: ICD-8 38710
  • Cause of death: ICD-10 H61.2
  • Cause of death: ICD-9 3804
  • Cause of death: ICD-8 38710

2 out of 7 registries used, show all original rules.

3743

4. Check minimum number of events

None

3743

5. Include endpoints

None

3743

6. Filter based on genotype QC (FinnGen only)

3743

Control definitions (FinnGen only)

Control exclude
H8_EXTERNAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H61
Name in latin
Cerumen obturans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28534 13931 14491
Only index persons 24697 12195 12502
Unadjusted period prevalence (%)
Whole population 0.40 0.40 0.40
Only index persons 0.46 0.45 0.48
Median age at first event (years)
Whole population 60.28 63.18 57.60
Only index persons 63.70 66.23 61.23

-FinnGen-

Key figures

All Female Male
Number of individuals 3743 1809 1934
Unadjusted period prevalence (%) 0.74 0.62 0.85
Median age at first event (years) 69.00 67.24 70.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3302
Matched controls
33020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H61.2
ICD-10 Finland
Impacted cerumen
5131.8
323.0
3273
665
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.3
210.8
925
2722
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.8
209.1
1091
3751
TDA90
NOMESCO Finland
Removal wax from ear
25.9
199.4
283
119
H81
ICPC
Excessive ear wax
3.7
182.1
998
3502
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
7.0
172.3
458
741
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
5.4
172.2
576
1249
DFF00
NOMESCO Finland
Pure tone audiometry
4.7
168.1
641
1601
H60.8
ICD-10 Finland
Other otitis externa
19.0
159.0
249
141
H60.3
ICD-10 Finland
Other infective otitis externa
22.7
137.9
203
95
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.9
131.7
1028
4473
UDC00
NOMESCO Finland
Ear microscopy
4.5
118.8
465
1163
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.3
111.9
458
1192
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
7.1
111.0
286
433
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
5.9
109.8
328
605
H60.9
ICD-10 Finland
Otitis externa, unspecified
5.3
100.3
330
681
DAX08
NOMESCO Finland
Fitting of hearing aid
4.9
97.9
344
763
H13
ICPC
Plugged feeling ear
2.5
86.5
820
3839
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.0
83.3
557
2108
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
72.4
567
2354
DFF15
NOMESCO Finland
Speech audiometry
4.3
72.1
286
711
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.8
64.4
293
823
H61.8
ICD-10 Finland
Other specified disorders of external ear
21.7
61.6
91
43
R5120
NOMESCO Finland
Preparation of an aid
5.4
59.8
188
364
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
5.5
59.1
182
344
SPAT1172
SPAT
Guidance concerning hydration
5.1
53.0
175
358
SPAT1234
SPAT
Support of social functional capacity
3.2
48.8
271
886
H60
ICD-10 Finland
Otitis externa
4.1
47.0
193
493
SPAT1360
SPAT
Extensive global examination
2.7
45.1
335
1325
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
6.6
44.9
119
186
A98
ICPC
Health maint/preventive medicine
2.4
43.3
3076
28051
H91.1
ICD-10 Finland
Presbycusis
2.8
42.7
306
1182
H65.3
ICD-10 Finland
Chronic mucoid otitis media
5.0
39.8
132
272
H25.8
ICD-10 Finland
Other senile cataract
2.1
38.6
467
2358
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
37.9
627
3584
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
5.3
37.7
118
228
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.2
37.3
204
658
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.8
37.1
259
983
H71
ICD-10 Finland
Cholesteatoma of middle ear
8.4
35.9
80
97
H02
ICPC
Hearing complaint
2.0
35.5
491
2615
H66.9
ICD-10 Finland
Otitis media, unspecified
2.9
35.5
229
827
J01DB01
ATC
cefalexin; oral
1.7
34.9
2546
22035
XF640
NOMESCO Finland
NA
3.7
34.2
155
432
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.3
32.0
169
532
SPAT1310
SPAT
Counselling related to known health issue
1.6
31.8
1029
7192
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.9
31.0
131
344
H92.0
ICD-10 Finland
Otalgia
2.9
30.7
192
679
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.0
30.6
126
323
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
30.5
1445
11065
N07CA01
ATC
betahistine; oral
2.3
30.2
293
1329
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
29.7
349
1729
H29
ICPC
Ear symptom/complaint other
2.1
29.3
371
1897
M75
ICD-10 Finland
Shoulder lesions
3.2
29.1
163
535
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
29.0
1486
11541
L28
ICPC
Limited function/disability (L)
1.8
28.3
570
3451
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.9
27.8
175
621
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
38.2
27.1
34
9
E0000UV
ATC
NA
1.5
27.1
1188
8861
H60.4
ICD-10 Finland
Cholesteatoma of external ear
52.1
26.2
31
6
H01
ICPC
Ear pain/earache
2.1
25.8
329
1686
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.5
25.5
205
843
H65.2
ICD-10 Finland
Chronic serous otitis media
6.2
25.4
69
113
J01CA04
ATC
amoxicillin; systemic
1.5
25.4
2441
21440
R01AD08
ATC
fluticasone; nasal
1.6
25.1
772
5257
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
25.1
485
2886
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
3.8
24.7
108
293
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
11.4
24.6
46
41
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
24.2
707
4746
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.2
23.9
244
1133
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
23.9
569
3608
H04
ICPC
Ear discharge
3.1
23.8
137
459
DC1AD
NOMESCO Finland
Temporalbone CT
8.8
23.7
51
59
J20
ICD-10 Finland
Acute bronchitis
2.1
23.7
299
1525
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
4.8
23.0
77
162
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
9.5
23.0
47
50
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
40.4
22.7
28
7
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
22.6
818
5779
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
22.6
528
3326
SPAT1312
SPAT
General health counselling
1.5
22.6
979
7212
N02BE01
ATC
paracetamol; systemic, rectal
1.5
22.5
2646
23868
SPAT1043
SPAT
Audiometry
1.8
22.3
389
2232
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
22.0
448
2705
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.1
21.7
265
1329
I78.1
ICD-10 Finland
Naevus, non-neoplastic
3.5
21.4
103
303
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
4.5
21.4
76
171
R01AD09
ATC
mometasone; nasal
1.5
21.0
1194
9271
AA1AD
NOMESCO Finland
CT of head and brain
1.5
20.9
791
5629
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.4
20.7
104
317
S02CA02
ATC
flumetasone and antiinfectives; otic
2.3
20.5
187
823
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.9
20.4
319
1761
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
19.6
732
5181
H93.1
ICD-10 Finland
Tinnitus
2.2
19.4
205
966
J01MA01
ATC
ofloxacin; systemic
1.9
19.3
284
1534
A02BC02
ATC
pantoprazole; systemic
1.4
19.1
1920
16451
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
19.0
877
6493
Z04
ICD-10 Finland
Examination and observation for other reasons
4.0
19.0
77
197
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.1
18.8
213
1034
UKC02
NOMESCO Finland
Cystoscopy
1.6
18.4
549
3678
SPAT1153
SPAT
Removal of sutures
1.4
18.4
970
7371
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
18.2
319
1830
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
18.1
888
6645
H84
ICPC
Presbyacusis
2.6
18.1
138
552
K03.66
ICD-10 Finland
Tooth plaque
2.0
18.0
227
1155
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
2.9
17.9
111
393
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.9
17.9
286
1591
SPAT1254
SPAT
Administration of medicine
1.6
17.9
492
3226
38710
ICD-8 Finland
Other disease of ear and mastoid process, Wax in ear
+∞
17.7
17
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
17.6
991
7617
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
17.4
287
1613
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.7
17.4
117
437
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.5
17.0
60
135
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
4.1
17.0
66
163
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
16.9
1210
9694
M15
ICD-10 Finland
Polyarthrosis
2.2
16.9
173
804
N03AX16
ATC
pregabalin; oral
1.5
16.6
674
4838
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
16.5
1068
8400
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
20.1
16.4
24
12
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.0
16.4
221
1156
J01MA12
ATC
levofloxacin; systemic
1.5
16.3
562
3887
SPAT1125
SPAT
Stoma care and guidance
3.4
16.2
79
237
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
16.0
1259
10223
H02AB04
ATC
methylprednisolone; systemic
1.6
16.0
418
2699
D01AE16
ATC
amorolfine; topical
1.7
16.0
347
2128
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
15.7
360
2240
R42
ICD-10 Finland
Dizziness and giddiness
1.5
15.7
677
4917
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
15.4
792
5952
G47.3
ICD-10 Finland
Sleep apnoea
1.5
15.4
553
3860
L57.0
ICD-10 Finland
Actinic keratosis
1.7
15.3
335
2057
J01AA02
ATC
doxycycline; systemic
1.4
15.3
2263
20280
J01FA10
ATC
azithromycin; systemic
1.3
15.1
1535
12951
SPAT1216
SPAT
Assessment of functional ability
1.5
15.1
517
3565
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.7
15.1
314
1901
J01FF01
ATC
clindamycin; systemic
1.4
15.1
734
5456
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.6
14.9
108
420
XF402
NOMESCO Finland
ECG with work load test
1.7
14.8
359
2268
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
3.9
14.6
60
157
S18
ICPC
Laceration/cut
1.4
14.6
1249
10239
NG2AA
NOMESCO Finland
Patella X-ray examination
2.7
14.3
101
388
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.6
14.2
366
2351
J01MA02
ATC
ciprofloxacin; systemic
1.4
14.0
1146
9308
DFE00
NOMESCO Finland
Insertion of cochlear implant
15.8
13.9
22
14
SPAT1053
SPAT
Memory test
1.5
13.8
516
3621
L03
ICPC
Low back symptom/complaint
1.4
13.8
637
4673
SPAT1167
SPAT
Insertion of urinary catheter
2.3
13.8
127
565
DFF16
NOMESCO Finland
Speech-in-noise audiometry
20.1
13.8
20
10
A04
ICPC
Weakness/tiredness general
1.6
13.7
400
2653
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
5.5
13.7
40
74
S82
ICPC
Naevus/mole
1.7
13.7
331
2088
P20
ICPC
Memory disturbance
1.6
13.7
414
2768
D07XC01
ATC
betamethasone, combinations; topical
1.6
13.6
336
2136
3804A
ICD-9 Finland
Disorders of external ear, Impacted cerumen
+∞
13.5
13
*
D07AC01
ATC
betamethasone; topical
1.4
13.4
937
7405
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
13.2
180
948
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
13.1
880
6909
J02AC01
ATC
fluconazole; systemic
1.4
13.0
956
7613
G04BD12
ATC
mirabegron; oral
1.6
12.9
322
2049
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
12.9
993
7961
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.5
12.9
430
2941
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
12.9
494
3486
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
12.9
421
2869
H74.1
ICD-10 Finland
Adhesive middle ear disease
9.0
12.7
26
29
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
5.3
12.7
38
73
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
2.8
12.6
82
301
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
12.4
438
3033
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
12.3
526
3790
A97
ICPC
No disease
1.5
12.3
441
3067
M54
ICD-10 Finland
Dorsalgia
1.7
12.3
285
1780
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
37.7
12.2
15
*
R01AD12
ATC
fluticasone furoate; nasal
1.4
12.2
682
5179
SPAT1211
SPAT
Application of soft bandage
1.7
12.2
284
1775
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
12.1
1101
9038
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
12.0
1888
16726
A02BC05
ATC
esomeprazole; systemic
1.3
11.9
1108
9117
Z04.3
ICD-10 Finland
Examination and observation following other accident
2.8
11.9
75
271
H02AB06
ATC
prednisolone; systemic
1.3
11.9
1316
11101
SPAT1260
SPAT
Consultation of another employee
1.5
11.9
510
3675
M79.6
ICD-10 Finland
Pain in limb
1.3
11.9
948
7622
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
3.7
11.9
50
135
X58
ICD-10 Finland
Exposure to other specified factors
1.6
11.9
338
2225
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
11.8
627
4711
S29
ICPC
Skin symptom/complaint other
1.5
11.7
469
3339
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
1.5
11.5
497
3586
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
4.2
11.5
42
100
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
11.4
418
2918
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
11.4
262
1632
SCA03
NOMESCO Finland
Preventive oral health care, extensive
2.1
11.3
131
646
ND1BA
NOMESCO Finland
Wrist extensive X-ray examination
2.6
11.2
78
299
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
11.2
192
1095
D01BA02
ATC
terbinafine; oral; topical
1.4
11.1
672
5157
R05
ICD-10 Finland
Cough
1.4
11.1
534
3935
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
11.1
742
5794
NF1DA
NOMESCO Finland
X-ray of hips
2.6
11.1
81
320
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.6
11.0
79
310
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.7
11.0
210
1237
R13
ICD-10 Finland
Dysphagia
1.8
11.0
187
1066
M01AE02
ATC
naproxen; oral, rectal
1.3
10.9
1523
13208
H25.0
ICD-10 Finland
Senile incipient cataract
1.8
10.9
195
1130
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
7.8
10.8
24
31
N03AE01
ATC
clonazepam; systemic
1.9
10.8
159
860
H65.0
ICD-10 Finland
Acute serous otitis media
3.4
10.8
51
152
H70.1
ICD-10 Finland
Chronic mastoiditis
8.8
10.7
22
25
L75
ICPC
Fracture: femur
3.2
10.6
55
176
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
10.6
485
3539
SPAT1263
SPAT
Sampling
1.3
10.6
1216
10268
D07AD01
ATC
clobetasol; topical
1.5
10.5
406
2861
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
10.4
679
5269
L15
ICPC
Knee symptom/complaint
1.4
10.4
559
4201
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
10.4
897
7269
J37.0
ICD-10 Finland
Chronic laryngitis
2.3
10.4
90
390
N17
ICPC
Vertigo/dizziness
1.5
10.4
332
2245
R06AX27
ATC
desloratadine; oral
1.4
10.3
622
4764
R06.0
ICD-10 Finland
Dyspnoea
1.4
10.3
701
5480
J34.2
ICD-10 Finland
Deviated nasal septum
2.0
10.3
134
692
K59.0
ICD-10 Finland
Constipation
1.8
10.3
175
996
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
10.3
379
2645
K03.81
ICD-10 Finland
Sensitive dentine
10.6
10.3
19
18
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
10.2
1021
8448
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.9
10.0
39
100
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
2.6
9.8
70
273
K59.09
ICD-10 Finland
Constipation, unspecified
1.7
9.8
196
1174
WZA90
NOMESCO Finland
Other doctors statement
1.4
9.8
587
4490
S01BC05
ATC
ketorolac; ophthalmic
1.9
9.8
133
701
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
9.8
314
2127
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
2.6
9.8
71
282
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
4.3
9.8
35
83
P01AB01
ATC
metronidazole; oral, rectal
1.3
9.7
984
8149
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.6
9.7
254
1639
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
9.6
447
3267
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.6
9.6
258
1676
4141
FHL
Myringoplasty (also for reasons other than inflammation)
6.8
9.6
23
34
D07AC13
ATC
mometasone; topical
1.3
9.6
753
6014
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.7
9.6
176
1029
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
9.5
206
1263
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
21.7
9.3
13
6
WX110
NOMESCO Finland
Local anesthesy
1.3
9.3
1873
16854
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.6
9.3
217
1359
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
13.7
9.2
15
11
R51.80
ICD-10 Finland
Headache
1.5
9.2
339
2370
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
4.1
9.1
34
84
PA7BD
NOMESCO Finland
CT angiography of neck and brain
2.6
9.1
62
238
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
9.0
264
1749
WX002
NOMESCO Finland
Sedation and analgesia
1.4
9.0
560
4306
J02AC02
ATC
itraconazole; systemic
1.4
9.0
445
3289
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
9.0
245
1598
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.9
1205
10323
SPAT1301
SPAT
No procedures
1.3
8.9
920
7615
DCD00
NOMESCO Finland
Myringoplasty
4.6
8.9
29
63
R06AE07
ATC
cetirizine; oral
1.3
8.9
1108
9401
D02AE01
ATC
carbamide; topical
1.7
8.8
171
1014
L02
ICPC
Back symptom/complaint
1.6
8.8
220
1403
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
3.4
8.8
40
118
R35
ICD-10 Finland
Polyuria
1.7
8.7
189
1161
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
50.1
8.7
10
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.5
8.7
326
2285
A02BC04
ATC
rabeprazole; oral
1.6
8.7
212
1343
Z00.0
ICD-10 Finland
General medical examination
1.4
8.6
509
3876
WX320
NOMESCO Finland
Spinalanesthesy
1.3
8.6
620
4876
M54.5
ICD-10 Finland
Low back pain
1.3
8.6
803
6557
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
3.1
8.4
43
138
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.0
8.4
101
510
DFX00
NOMESCO Finland
Connecting cochlear implant
12.8
8.4
14
11
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
3.0
8.3
46
156
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
7.9
8.3
18
23
Q90.9
ICD-10 Finland
Down syndrome, unspecified
+∞
8.3
8
*
H02AB07
ATC
prednisone; oral
1.4
8.3
384
2801
M79.1
ICD-10 Finland
Myalgia
1.5
8.3
303
2109
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.9
8.2
114
607
J01DA01
ATC
[U] cefalexin; systemic
1.2
8.2
1723
15473
XG410
NOMESCO Finland
Flow-volume spirometry
1.8
8.2
126
697
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.2
491
3749
H81.3
ICD-10 Finland
Other peripheral vertigo
2.2
8.2
76
345
E03
ICD-10 Finland
Other hypothyroidism
1.7
8.2
153
902
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
8.2
1744
15689
N03AX09
ATC
lamotrigine; oral
2.0
8.2
99
502
H60.0
ICD-10 Finland
Abscess of external ear
7.5
8.1
18
24
L01
ICPC
Neck symptom/complaint
1.4
8.1
335
2392
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
8.1
8.1
17
21
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
6.8
8.1
19
28
N05AH03
ATC
olanzapine; systemic
1.8
8.0
128
715
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.7
8.0
169
1031
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
8.0
155
921
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
8.0
273
1875
L76
ICPC
Fracture: other
2.2
8.0
79
366
G44.2
ICD-10 Finland
Tension-type headache
1.5
8.0
294
2049
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.9
7.9
110
589
SPAT1229
SPAT
Assessment of need for aid
1.5
7.9
242
1624
R74
ICPC
Upper respiratory infection acute
1.3
7.8
624
4973
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
4.3
7.8
27
63
DCD10
NOMESCO Finland
Tympanoplasty
8.5
7.8
16
19
D82
ICPC
Teeth/gum disease
1.3
7.7
815
6743
L16
ICPC
Ankle symptom/complaint
1.5
7.7
253
1723
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
2.4
7.6
63
269
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
7.6
788
6502
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
7.6
283
1981
J01FA09
ATC
clarithromycin; systemic
1.3
7.6
766
6303
J01DC02
ATC
cefuroxime; systemic
1.8
7.6
133
768
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.5
393
2931
H10
ICD-10 Finland
Conjunctivitis
1.7
7.5
147
877
Z01.2
ICD-10 Finland
Dental examination
1.2
7.5
1033
8820
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
7.5
235
1583
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.5
618
4948
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
7.5
379
2810
TQW99
NOMESCO Finland
Other minor procedure on skin
1.7
7.5
145
865
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.4
7.4
426
3230
J31.2
ICD-10 Finland
Chronic pharyngitis
5.0
7.4
22
44
XKW99
NOMESCO Finland
Other physiological examination of urinary or male genital system
2.8
7.4
45
164
H80.9
ICD-10 Finland
Otosclerosis, unspecified
3.4
7.3
33
98
38798
ICD-8 Finland
Other disease of ear and mastoid process, Alii definiti
+∞
7.3
7
*
RK420
NOMESCO Finland
NA
9.4
7.3
14
15
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.3
7.3
537
4233
E000001
ATC
NA
1.3
7.2
512
4007
T16
ICD-10 Finland
Foreign body in ear
3.4
7.2
33
99
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
7.2
665
5407
A06AC51
ATC
ispaghula, combinations; systemic
1.8
7.2
124
712
H60.1
ICD-10 Finland
Cellulitis of external ear
3.5
7.2
31
89
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.0
7.1
89
459
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
7.1
527
4153
D10.09
ICD-10 Finland
Benign tumor of the lip UNS
7.9
7.1
15
19
UJF32
NOMESCO Finland
Coloscopy
1.3
7.1
705
5784
DFF59
NOMESCO Finland
Other assessment of balance
3.5
7.1
31
90
J01DC04
ATC
cefaclor; oral
2.9
7.1
39
134
L17
ICPC
Foot/toe symptom/complaint
1.3
7.1
674
5500
A03FA02
ATC
cisapride; oral, rectal
1.5
7.1
215
1443
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.7
7.0
137
820
S21
ICPC
Skin texture symptom/complaint
1.4
7.0
323
2357
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.0
7.0
88
456
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.0
698
5730
B01AF02
ATC
apixaban; oral
1.4
7.0
289
2067
M01AH05
ATC
etoricoxib; oral
1.2
7.0
1465
13068
SPAT1325
SPAT
Vaccination
1.2
7.0
1045
9000
N05BA06
ATC
lorazepam; systemic, sublingual
1.7
6.9
138
831
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.0
6.8
80
402
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.6
6.8
158
990
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
10.9
6.8
12
11
N05BA12
ATC
alprazolam; oral
1.5
6.8
239
1656
H91
ICD-10 Finland
Other hearing loss
3.2
6.7
33
105
R02
ICPC
Shortness of breath/dyspnoea
1.4
6.7
326
2402
ELB50
NOMESCO Finland
Total parotidectomy
7.2
6.7
15
21
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
3.9
6.7
25
64
R55
ICD-10 Finland
Syncope and collapse
1.4
6.6
302
2198
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
6.6
461
3600
H28
ICPC
Limited function/disability (H)
3.1
6.6
34
112
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
5.9
6.6
17
29
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
5.5
6.6
18
33
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.5
581
4692
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.7
6.5
126
753
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
6.5
401
3068
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
1.8
6.5
109
622
J01AA04
ATC
lymecycline; systemic
1.4
6.5
285
2064
ACC51
NOMESCO Finland
Release of median nerve
1.6
6.5
161
1031
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.6
6.4
175
1145
XKD00
NOMESCO Finland
Uroflowmetry
1.3
6.4
480
3785
M75.8
ICD-10 Finland
Other shoulder lesions
2.0
6.4
75
378
D07CC01
ATC
betamethasone and antibiotics; topical
1.4
6.4
303
2221
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
2.4
6.4
50
211
AA1XD
NOMESCO Finland
Other special CT of head and brain
4.7
6.4
20
43
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
14.3
6.4
10
7
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
6.4
451
3531
H66
ICD-10 Finland
Suppurative and unspecified otitis media
2.1
6.4
63
297
H70
ICPC
Otitis externa
2.3
6.3
52
224
ZXC15
NOMESCO Finland
Use of photodynamic technique
2.5
6.3
48
197
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
2.0
6.3
78
401
N05AH04
ATC
quetiapine; oral
1.4
6.3
360
2725
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
18.0
6.3
9
5
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
6.2
121
722
C09CA06
ATC
candesartan; oral
1.3
6.2
529
4244
R03AC02
ATC
salbutamol; inhalant
1.2
6.2
1376
12289
D06BB10
ATC
imiquimod; topical
1.7
6.2
119
708
R60.0
ICD-10 Finland
Localized oedema
1.4
6.2
295
2164
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.2
1748
15974
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
1.9
6.2
86
463
ZXA10
NOMESCO Finland
Bilateral
1.3
6.2
516
4130
S97
ICPC
Chronic ulcer skin
1.6
6.2
147
929
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
5.0
6.2
18
36
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.0
6.2
73
370
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.2
629
5167
S01EE01
ATC
latanoprost; ophthalmic
1.5
6.2
178
1183
S77
ICPC
Malignant neoplasm of skin
2.8
6.2
37
135
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
5.3
6.1
17
32
R4130
NOMESCO Finland
Speech therapy
2.1
6.1
64
309
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
3.3
6.1
28
85
P85
ICPC
Mental retardation
5.7
6.1
16
28
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.9
6.1
87
470
J33.8
ICD-10 Finland
Other polyp of sinus
2.3
6.1
53
235
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
1.9
6.1
87
473
F32
ICD-10 Finland
Depressive episode
1.8
6.1
104
601
WX722
NOMESCO Finland
PEEP
1.7
6.0
123
748
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
4.9
6.0
18
37
SPAT1147
SPAT
Destruction of skin lesion with external methods
2.3
6.0
52
229

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1033
3773
3.40
221.16
5.1
4.6
33.1
33.1
%
0.00
488
2509
864
3214
3.19
175.20
5.0
4.5
—
—
—
0
0
1502
9283
2.03
91.02
5.0
4.2
—
—
—
0
0
410
1500
2.95
81.64
4.8
4.5
24.6
24.7
mmol/l
0.43
358
1400
118
191
6.35
69.84
3.4
3.0
—
—
—
0
0
2038
14798
1.83
69.20
6.5
6.2
1.2
1.2
mmol/l
5.40
1613
13385
1572
10709
1.81
64.46
6.4
5.8
—
—
—
0
0
412
1729
2.55
62.21
4.7
4.4
—
—
—
0
0
1822
13313
1.72
55.80
2.3
2.1
99.0
93.8
pmol/l
3.07
763
6948
492
2361
2.25
54.62
4.7
4.2
5.1
5.1
kpa
0.16
425
2190
488
2338
2.25
54.37
4.8
4.2
7.4
7.4
ph
0.75
24
269
3150
27124
2.02
53.05
5.5
4.7
2.5
2.0
mu/l
0.53
2508
24567
1029
6508
1.80
51.58
2.0
1.8
1057.5
1168.2
nmol/l
2.70
538
4888
3455
30988
2.49
50.06
20.8
18.7
139.4
139.6
mmol/l
2.34
3302
30189
3459
31051
2.50
49.82
20.9
18.8
4.0
4.0
mmol/l
0.21
3297
30194
2092
16332
1.64
46.05
7.0
6.9
1.2
1.2
mmol/l
4.81
1598
13769
3579
32841
3.05
46.01
26.6
23.2
242.9
245.8
e9/l
1.80
3452
31889
2580
21256
1.69
45.82
5.3
4.5
—
—
—
0
0
3579
32856
3.04
45.67
26.5
23.1
30.4
30.3
pg
0.72
3480
32296
3579
32858
3.04
45.63
26.6
23.2
4.4
4.4
e12/l
4.12
3437
31785
3579
32865
3.03
45.47
26.7
23.2
6.8
6.8
e9/l
0.12
3439
31792
3579
32866
3.03
45.45
26.8
23.3
133.2
134.0
g/l
2.78
3474
32312
3578
32853
3.02
45.43
26.6
23.1
91.3
91.2
fl
1.05
3478
32293
1905
14568
1.63
45.29
6.3
5.9
58.0
57.6
%
0.59
1647
13584
1623
11948
1.63
44.90
2.5
2.2
—
—
—
0
0
1891
14471
1.62
44.54
6.9
6.3
8.7
8.8
%
0.45
1637
13503
1925
14796
1.62
44.52
6.8
6.1
27.0
27.2
%
0.35
1656
13732
2684
22416
1.70
44.52
4.9
4.1
13.1
13.2
mm/h
0.08
2240
20616
1882
14400
1.62
44.24
6.4
6.0
2.9
2.9
%
0.04
1626
13389
3347
29927
2.12
43.81
18.1
15.8
24.7
25.5
mg/l
0.69
2699
24092
409
1985
2.19
43.70
3.0
3.2
4.3
4.2
e9/l
0.25
155
1504
1836
14003
1.61
43.43
6.7
6.1
0.7
0.7
%
0.25
1572
13043
3408
30704
2.23
43.41
18.5
15.0
—
—
—
0
0
3464
31465
2.35
42.42
12.1
10.8
27.2
25.7
u/l
0.61
3159
30214
1124
7629
1.68
42.20
2.5
2.5
—
—
—
0
0
2790
23705
1.70
41.59
7.7
7.5
80.5
81.4
u/l
0.49
2473
22251
2270
18370
1.60
40.68
3.6
3.2
51.3
51.9
u/l
0.11
1930
16860
3044
26595
1.77
39.78
18.7
17.2
39.8
39.1
%
4.00
1815
17889
142
425
3.43
39.24
1.7
2.2
18.6
24.1
mg/l
0.55
19
103
1629
12285
1.58
38.93
4.9
4.0
45.0
94.4
ng/l
0.78
1262
9064
3206
28556
1.86
37.82
5.5
4.8
6.0
6.0
mmol/l
0.17
2531
25702
3095
27285
1.78
37.73
4.5
4.1
1.3
1.3
mmol/l
0.56
2458
24579
3200
28512
1.84
37.35
5.0
4.5
4.5
4.5
mmol/l
1.09
2562
26101
3253
29215
1.87
35.85
5.4
5.1
2.6
2.6
mmol/l
0.99
2597
26593
121
349
3.55
35.40
2.7
2.6
—
—
—
0
0
3169
28270
1.79
35.26
5.4
4.5
1.5
1.4
mmol/l
0.50
2538
25697
1637
12568
1.54
34.83
2.5
2.3
79.5
78.0
nmol/l
1.06
1204
11163
3070
27199
1.72
34.29
7.1
6.2
40.3
40.4
mmol/mol
0.35
2463
24949
1344
9921
1.55
33.95
2.5
2.6
—
—
—
0
0
2456
20671
1.55
33.50
5.6
4.8
991.5
1896.2
e6/l
0.72
26
345
1094
7866
1.55
30.33
1.6
1.6
21.5
20.3
nmol/l
1.30
740
6693
1951
15845
1.48
29.94
6.4
6.0
0.2
0.2
e9/l
0.21
1563
13755
3412
31494
1.94
29.22
18.7
18.6
82.2
80.5
umol/l
1.68
3412
31483
582
3636
1.71
28.37
2.1
1.7
—
—
—
0
0
553
3407
1.73
28.35
1.6
1.4
—
—
—
0
0
1282
9680
1.49
27.67
2.3
2.2
201.4
226.9
u/l
0.50
1163
9035
2227
18730
1.47
27.51
4.7
4.9
6.7
6.8
mmol/l
1.54
2106
17552
1331
10144
1.48
27.35
3.5
3.2
1687.1
1694.5
ng/l
0.02
1021
8798
2578
22437
1.48
25.77
4.4
3.9
15.0
14.9
pmol/l
0.10
2024
20178
1952
16287
1.41
23.37
5.6
6.2
11.5
12.2
umol/l
1.70
1758
15426
1847
15350
1.40
22.13
6.2
5.8
0.0
0.0
e9/l
0.09
1518
13119
1836
15283
1.40
21.57
6.2
5.8
0.6
0.6
e9/l
0.55
1509
13049
1369
10859
1.41
21.25
3.0
3.4
2.4
2.4
mmol/l
0.71
919
9389
391
2361
1.73
21.23
2.2
2.3
—
—
—
0
0
1873
15675
1.39
21.14
6.3
5.9
1.9
1.9
e9/l
0.25
1550
13641
1560
12689
1.39
20.75
3.0
2.9
137.9
141.9
ug/l
0.13
1297
11612
1635
13462
1.38
19.94
8.9
10.4
1.3
1.3
inr
0.43
347
3769
101
377
2.73
19.16
2.7
4.1
—
—
—
0
0
1099
8518
1.41
18.98
2.5
2.3
3.0
3.0
mg/l
0.20
816
7260
2195
24702
0.73
18.62
21.6
20.7
332.3
332.1
g/l
0.37
2182
24476
1222
9683
1.39
18.41
2.7
2.6
58.4
58.4
u/l
0.00
1035
8907
407
2597
1.64
17.84
4.3
4.0
95.8
92.7
ng/l
0.20
290
2232
585
4121
1.50
16.51
1.3
1.3
—
—
—
0
0
94
371
2.57
16.02
1.2
1.2
—
—
—
0
0
204
1102
1.90
15.95
3.0
3.1
41.8
111.5
mg/l
0.75
174
890
199
1072
1.90
15.70
3.0
3.1
1.3
1.5
ratio
0.38
13
77
203
1101
1.89
15.69
3.0
3.2
41.1
62.5
mg/l
0.70
175
893
165
837
2.02
15.50
1.5
1.4
7.6
14.8
iu/ml
—
6
19
2048
17862
1.32
15.43
8.8
8.8
4.2
4.2
e9/l
0.41
1677
15509
1375
11336
1.34
15.35
6.0
5.3
2.3
4.1
ug/l
3.11
1103
10100
744
5593
1.41
14.74
1.4
1.5
2.4
2.5
g/l
0.72
359
3257
631
4633
1.44
14.21
31.6
28.0
1.4
1.4
inr
0.02
55
646
444
3076
1.50
13.43
2.2
2.6
66.7
68.4
e9/l
0.46
345
2329
1673
14375
1.30
13.22
3.9
4.2
—
—
—
0
0
83
340
2.47
13.16
1.3
1.2
—
—
—
0
0
827
6449
1.36
12.92
3.6
3.2
0.9
0.8
ug/l
0.42
546
4519
1138
9317
1.32
12.76
4.2
4.3
—
—
—
0
0
200
1160
1.77
12.47
2.0
2.2
360.0
703.5
ug/l
1.04
181
1095
506
3670
1.44
12.05
1.4
1.3
572.2
520.0
titre
0.22
118
771
196
1149
1.74
11.78
3.4
3.4
0.3
0.3
g/l
0.32
76
493
223
1356
1.69
11.74
2.8
2.7
—
—
—
0
0
219
1333
1.68
11.49
1.2
1.2
—
—
—
0
0
601
4547
1.38
11.18
2.8
2.6
22.2
22.4
%
0.08
479
3861
77
333
2.34
10.90
2.3
3.4
60.6
58.7
%
0.22
44
205
450
3256
1.43
10.81
1.3
1.3
—
—
—
0
0
673
5216
1.35
10.73
2.7
2.5
13.0
12.6
umol/l
0.66
564
4824
260
1687
1.58
10.57
1.4
1.3
53.0
56.8
au/ml
—
7
70
214
1325
1.65
10.54
1.4
1.5
38.8
19.3
u/ml
—
5
34
788
6291
1.32
10.21
1.4
1.3
2.1
1.8
u/ml
0.29
140
1551
528
3969
1.38
10.16
1.3
1.3
—
—
—
0
0
421
3051
1.43
10.01
2.2
2.4
5.9
7.0
ug/l
0.77
221
2652
222
1406
1.62
10.00
1.8
1.9
4.8
2.3
ug/l
0.40
138
1230
622
4839
1.34
9.58
2.7
2.5
2.3
2.3
g/l
1.49
525
4464
173
1046
1.69
9.35
1.7
2.2
37.5
37.4
g/l
0.03
107
904
516
6686
0.74
9.35
4.2
4.3
1.0
1.0
kg/l
0.13
96
1053
580
4486
1.35
9.27
6.6
5.9
1.1
1.1
mmol/l
0.25
498
4169
29
80
3.65
9.25
1.7
2.1
—
—
—
0
0
451
3358
1.39
9.16
2.4
2.3
114.8
149.4
ug/g
1.92
301
2638
536
4105
1.36
9.13
2.3
2.7
1.8
1.8
%
0.07
407
3615
306
2125
1.48
9.10
1.5
1.4
—
—
—
0
0
975
8122
1.27
8.96
3.1
2.8
5510.7
5781.9
umol/l
0.06
744
6931
394
2879
1.41
8.92
2.4
2.5
66.5
66.1
g/l
0.42
299
2617
258
1738
1.52
8.89
2.7
2.4
—
—
—
0
0
68
307
2.24
8.78
1.2
1.1
—
—
—
0
0
323
2288
1.45
8.67
1.2
1.2
—
—
—
0
0
1929
21189
0.82
8.56
4.0
4.1
—
—
—
0
0
319
2264
1.45
8.48
2.5
2.8
10.6
10.5
g/l
0.15
266
2067
272
1875
1.49
8.40
2.7
2.4
43.1
21.7
au/ml
1.44
20
82
241
1628
1.51
8.21
1.5
1.7
1.6
1.5
g/l
0.24
186
1398
415
3105
1.38
8.16
2.5
2.2
0.2
0.2
g/l
0.98
372
2886
103
561
1.86
8.01
1.5
1.5
—
—
—
0
0
149
904
1.68
8.00
1.6
1.4
252.6
272.7
ug/g
0.55
84
529
193
1254
1.57
7.86
2.3
2.3
9.7
10.2
g/l
0.76
120
1068
125
730
1.74
7.73
1.6
1.5
—
—
—
0
0
53
228
2.34
7.70
1.7
1.7
—
—
—
0
0
837
6957
1.26
7.67
1.6
1.7
30798923.6
25241950.8
pmol/l
0.09
526
5693
1572
13988
1.21
7.54
4.9
4.9
35.3
35.0
g/l
0.88
1342
12942
566
4494
1.31
7.44
2.1
2.0
—
—
—
0
0
2279
24460
0.83
7.27
21.1
19.3
13.7
13.8
%
1.78
2240
23892
159
1007
1.60
7.24
1.4
1.6
—
—
—
0
0
254
1784
1.45
7.16
1.5
1.9
1.3
1.4
g/l
0.16
206
1624
1156
10027
1.22
7.06
3.4
3.2
7.2
7.4
mmol/l
0.35
808
8376
90
494
1.84
6.88
1.3
1.4
—
—
—
0
0
933
7935
1.23
6.86
4.0
4.1
86.7
86.3
%
0.18
905
7742
1094
9477
1.22
6.70
3.5
3.3
533.0
303.8
mg/l
0.73
609
6077
41
168
2.46
6.67
2.5
3.2
20.8
19.5
mu/l
0.09
36
160
115
686
1.70
6.64
1.2
1.2
5.8
4.1
u/ml
—
10
62
782
6558
1.24
6.51
1.8
1.8
1.3
1.4
mg/l
0.21
558
5036
115
697
1.67
6.28
1.2
1.2
2.2
7.6
u/ml
1.69
14
107
108
1745
0.61
6.15
1.3
1.3
—
—
—
0
0
20
58
3.46
6.00
1.2
1.1
—
—
—
0
0
17
44
3.88
5.98
1.2
1.6
135.1
103.3
ng/l
—
10
30
31
122
2.55
5.53
1.2
1.1
70.0
393.5
ng/l
—
9
32
534
4369
1.26
5.47
1.2
1.2
25.2
13.4
u/ml
0.45
135
1608
92
547
1.70
5.44
2.7
3.7
2.1
1.6
%
0.25
60
417
128
827
1.57
5.44
3.3
3.3
—
—
—
0
0
23
78
2.96
5.41
1.8
1.9
—
—
—
0
0
68
374
1.83
5.26
1.5
1.5
63.0
62.6
%
0.03
40
237
1129
10007
1.18
5.13
4.3
4.0
12.1
9.3
mg/mmol
0.92
614
6386
287
2183
1.34
5.11
2.3
2.1
11.5
12.3
nmol/l
0.80
228
1889
31
128
2.43
5.04
1.3
1.2
—
—
—
0
0
553
4588
1.24
5.00
1.3
1.2
33.6
38.0
iu/ml
0.29
140
1396
21
71
2.97
4.98
1.0
1.1
170.0
266.2
pmol/l
—
8
53
221
1621
1.39
4.96
3.1
3.3
4.3
4.5
pmol/l
0.99
174
1412
20
67
3.00
4.82
1.1
1.3
61.7
67.1
mu/l
—
8
55
153
2166
0.69
4.69
5.8
6.7
24.7
24.4
mmol/l
0.34
142
2009
26
103
2.53
4.62
1.2
1.2
43.3
37.9
g/l
0.59
13
52
87
1369
0.63
4.51
5.2
4.5
—
—
—
0
0
118
785
1.52
4.47
1.6
1.6
20346.6
15014.8
e6/l
0.47
66
563
37
175
2.13
4.43
1.1
14.1
—
—
—
0
0
342
2720
1.28
4.43
1.4
1.4
—
—
—
0
0
134
918
1.48
4.41
5.8
5.7
1.7
1.5
mg/l
1.18
116
838
11
26
4.24
4.35
1.8
1.5
—
—
—
0
0
29
128
2.28
4.12
1.1
1.1
—
—
—
0
0
24
98
2.46
4.04
1.1
1.6
—
—
—
0
0
154
2114
0.72
3.99
3.4
3.5
129.1
127.9
g/l
0.26
148
2055
242
1872
1.31
3.89
1.2
1.2
—
—
—
0
0
31
145
2.15
3.86
1.0
1.0
—
—
—
0
0
8
11
7.29
3.86
1.0
1.1
—
—
—
0
0
16
54
2.97
3.84
2.2
2.2
3.1
3.2
ug/l
—
7
21
91
593
1.55
3.84
1.7
1.7
—
—
—
0
0
716
8161
0.85
3.79
4.3
4.2
0.0
0.0
estimate
0.37
257
2664
6
5
12.02
3.76
1.0
1.0
—
—
—
0
0
96
1412
0.67
3.67
4.0
5.2
0.8
0.9
%
0.39
86
1316
108
742
1.47
3.57
1.7
1.9
11.8
11.6
mg/l
0.07
90
676
18
68
2.66
3.56
1.1
1.1
—
—
—
0
0
18
68
2.66
3.56
1.1
1.1
—
—
—
0
0
18
68
2.66
3.56
1.1
1.1
—
—
—
0
0
338
2764
1.24
3.51
2.1
2.2
377.9
373.3
nmol/l
0.16
278
2515
13
41
3.18
3.49
2.9
2.3
14.4
17.3
umol/l
0.39
13
41
117
830
1.42
3.30
1.3
1.5
1.3
1.2
g/l
1.32
110
787
114
805
1.43
3.29
1.3
1.5
0.2
0.2
g/l
0.27
106
766
59
361
1.64
3.28
1.3
1.3
—
—
nmol/l
—
0
0
325
2669
1.24
3.26
3.2
3.6
—
—
—
0
0
408
3431
1.21
3.25
3.3
4.0
9.6
21.9
ug/l
1.57
286
2827
67
425
1.59
3.23
1.2
1.6
0.7
0.8
g/l
0.94
44
328
20
84
2.39
3.22
1.7
1.6
16.0
14.8
pmol/l
0.44
15
71
30
152
1.98
3.09
1.9
1.6
—
9.3
—
0
10
209
1640
1.29
3.08
1.4
1.3
295.3
232.4
u/ml
0.54
196
1508
58
910
0.63
3.07
4.5
4.5
—
—
—
0
0
178
1375
1.31
2.97
1.9
1.9
—
—
—
0
0
1097
10044
1.13
2.91
3.3
3.3
—
—
—
0
0
559
6370
0.86
2.90
4.6
4.6
—
—
—
0
0
599
5272
1.16
2.83
3.4
3.1
2.5
2.2
e6/l
0.39
330
2932
87
1234
0.70
2.82
3.9
3.6
1.5
1.4
mmol/l
0.15
87
1213
602
5303
1.16
2.81
3.7
3.4
0.8
0.8
mmol/l
0.26
531
4925
373
3158
1.20
2.79
8.6
7.3
10.7
10.3
mmol/l
0.36
331
3001
21
97
2.17
2.76
1.6
1.3
69.3
392.4
ug/l
0.62
14
49
65
961
0.67
2.65
9.5
11.1
—
—
—
0
0
106
1428
0.73
2.54
4.0
5.2
1.8
1.6
%
0.95
97
1329
6
11
5.46
2.54
1.0
1.3
—
—
—
0
0
48
748
0.64
2.53
4.4
3.6
21.9
28.8
mg/l
1.00
34
477
268
3215
0.82
2.52
7.0
7.6
121.1
120.8
g/l
0.08
260
3091
34
194
1.76
2.50
1.4
1.5
—
—
—
0
0
65
437
1.50
2.49
4.7
4.7
390.2
353.3
umol/l
0.93
52
380
42
255
1.65
2.48
1.5
1.4
25.3
26.5
u/l
0.07
24
209
45
280
1.61
2.42
3.7
2.6
20.5
20.1
nmol/l
0.11
38
264
62
416
1.50
2.41
1.3
1.3
0.2
0.4
nmol/l
—
5
26
48
304
1.59
2.41
1.2
1.2
—
—
—
0
0
5
8
6.26
2.37
2.0
1.8
—
—
—
0
0
65
443
1.48
2.35
1.0
1.1
—
9.6
—
0
20
75
1049
0.71
2.30
4.1
3.8
3.9
3.9
mmol/l
0.21
69
966
129
998
1.30
2.21
1.4
1.2
0.8
0.8
u/ml
—
5
90
21
107
1.97
2.20
1.5
1.4
3.7
3.3
mmol/l
0.20
21
95
27
462
0.58
2.14
2.1
2.4
105.9
105.5
mmol/l
0.16
27
455
27
152
1.78
2.11
2.3
2.3
57.1
55.5
umol/l
0.08
16
124
18
88
2.05
2.11
1.8
1.4
21.3
20.9
%
0.03
18
68
1409
14917
0.91
2.05
3.8
3.8
0.0
0.0
estimate
0.00
260
2762
46
301
1.53
2.05
2.0
1.7
—
—
—
0
0
47
310
1.52
2.03
1.1
1.2
—
—
—
0
0
64
450
1.43
2.02
3.8
2.8
—
—
—
0
0
27
454
0.59
2.02
2.1
2.4
—
—
—
0
0
30
178
1.69
1.98
1.2
1.1
—
—
—
0
0
29
171
1.70
1.96
1.1
1.0
—
—
—
0
0
28
462
0.60
1.95
2.1
2.4
4.1
4.1
mmol/l
0.15
28
455
63
447
1.42
1.91
5.6
6.6
10.6
12.2
mg/l
2.11
56
412
106
818
1.30
1.89
3.0
3.1
0.8
0.8
nmol/l
0.28
58
622
297
3430
0.85
1.87
4.7
4.2
1.3
1.9
mmol/l
2.95
249
2737
55
384
1.44
1.83
1.3
1.3
—
—
—
0
0
299
3441
0.86
1.80
4.7
4.1
5.7
5.8
kpa
1.53
290
3331
83
624
1.34
1.79
1.5
1.5
66.1
64.9
mmol/l
0.08
60
505
34
215
1.59
1.79
1.1
1.4
1.0
1.2
promille
0.33
28
171
41
272
1.51
1.76
1.2
1.3
—
—
—
0
0
212
1788
1.20
1.75
6.9
8.9
24.3
24.3
mmol/l
0.07
195
1671
12
54
2.23
1.73
1.0
1.1
—
—
—
0
0
7
24
2.92
1.72
1.0
1.1
—
—
—
0
0
46
315
1.47
1.71
1.3
1.6
—
—
—
0
0
28
171
1.64
1.70
4.6
4.0
—
—
—
0
0
1440
15133
0.92
1.68
3.9
3.9
0.0
0.0
estimate
1.08
262
2715
55
761
0.72
1.67
4.6
7.1
104.0
105.3
mmol/l
1.20
46
669
197
1659
1.20
1.66
1.3
1.2
153.8
145.2
iu/ml
0.09
60
594
61
443
1.38
1.66
1.1
1.1
0.9
1.7
u/ml
0.61
36
232
23
134
1.72
1.66
18.5
13.1
836.2
791.9
nmol/l
0.17
23
128
55
760
0.72
1.65
4.6
7.1
10.7
11.2
mmol/l
0.64
46
668
95
739
1.29
1.64
1.5
1.6
778.2
539.4
mg/l
0.58
87
695
1423
14934
0.92
1.58
5.3
5.2
0.0
0.0
estimate
0.50
275
2793
559
6119
0.90
1.57
2.9
3.1
2.5
2.5
mmol/l
0.34
484
5339
276
3158
0.86
1.57
3.4
3.0
211.8
229.7
ng/l
0.29
248
2881
330
2913
1.15
1.56
1.6
1.5
—
—
—
0
0
26
160
1.63
1.55
4.9
4.1
—
—
—
0
0
390
3485
1.13
1.54
1.6
1.6
—
—
—
0
0
67
501
1.34
1.54
1.2
1.2
2.4
2.5
u/ml
0.01
36
246
390
3487
1.13
1.53
3.0
2.9
6.5
8.9
umol/l
2.78
326
3042
130
1584
0.81
1.53
2.6
2.9
0.7
0.7
%
0.42
125
1513
16
86
1.86
1.50
2.0
1.7
—
—
—
0
0
38
259
1.47
1.48
2.5
2.6
5.3
11.2
umol/l
1.47
24
184
322
2852
1.14
1.47
2.3
2.4
41.3
55.2
u/l
0.37
280
2428
143
1714
0.83
1.44
3.4
3.6
—
—
—
0
0
5
16
3.13
1.44
3.6
3.0
4.6
4.3
mmol/l
—
5
16
252
2879
0.87
1.42
4.0
3.7
4.7
4.6
kpa
0.44
243
2781
197
2293
0.85
1.42
3.7
4.6
—
—
—
0
0
39
270
1.45
1.41
1.2
1.3
2.7
2.9
g/l
0.30
23
191
39
270
1.45
1.41
1.2
1.3
0.4
0.4
g/l
0.15
24
192
39
270
1.45
1.41
1.2
1.3
7.6
7.1
g/l
0.29
23
192
61
457
1.34
1.41
1.1
1.1
3.9
5.9
u/ml
0.56
39
263
24
149
1.61
1.40
1.1
1.2
135.6
138.5
nmol/l
0.13
24
149
90
713
1.27
1.39
2.0
1.7
39.8
41.8
nmol/l
0.33
78
684
59
441
1.34
1.39
1.1
1.1
—
—
—
0
0
34
230
1.48
1.38
1.0
1.0
289.6
291.8
mg/l
0.05
27
206
83
1049
0.79
1.38
4.0
6.3
1.4
1.3
mmol/l
0.44
69
912
185
2157
0.85
1.37
8.3
8.3
1.3
1.3
%
0.08
185
2143
26
166
1.57
1.37
1.4
1.3
2.1
1.1
nmol/l
—
9
129
78
610
1.28
1.34
1.2
1.3
207.2
225.1
miu/ml
0.15
28
260
187
1603
1.18
1.34
1.2
1.3
—
—
—
0
0
0
38
0.00
1.34
0.0
1.2
—
17.6
—
0
32
90
717
1.26
1.34
2.0
1.6
335.5
303.4
mu/l
0.30
80
660
6
24
2.50
1.30
1.0
1.1
—
—
—
0
0
75
587
1.28
1.29
1.5
1.4
—
—
—
0
0
829
7783
1.08
1.26
1.7
1.6
1.4
1.3
mmol/l
0.43
693
6484
18
107
1.69
1.25
1.1
1.2
—
—
—
0
0
268
2374
1.14
1.25
3.5
3.8
0.7
0.6
%
0.24
65
532
125
1042
1.21
1.24
5.7
4.3
9.1
8.4
kpa
3.13
114
974
228
2593
0.87
1.24
5.0
4.1
—
—
—
0
0
185
2136
0.86
1.24
8.5
8.5
93.6
93.9
%
0.21
185
2127
605
5611
1.09
1.23
3.3
2.9
0.8
1.2
e6/l
2.20
337
3240
63
486
1.30
1.22
1.2
1.3
—
—
—
0
0
677
7251
0.92
1.22
3.4
3.8
—
—
—
0
0
186
2144
0.86
1.22
8.3
8.4
0.6
0.7
%
1.69
186
2127
156
1331
1.18
1.21
1.2
1.1
28.9
154.0
titre
—
9
33
8
38
2.11
1.18
1.0
2.9
—
—
—
0
0
62
481
1.29
1.17
1.9
1.7
—
—
—
0
0
11
57
1.93
1.17
3.5
1.9
—
63.5
—
0
6
454
4167
1.10
1.16
1.8
1.8
—
—
—
0
0
101
832
1.22
1.15
1.5
1.5
26.1
27.4
iu/l
0.15
84
683
747
7944
0.93
1.13
1.3
1.4
—
—
—
0
0
560
5197
1.09
1.13
2.3
2.2
29.8
30.0
s
0.48
539
5029
5
114
0.44
1.12
2.4
1.3
32.8
60.8
%
—
5
95
29
200
1.45
1.12
1.7
2.6
0.4
0.2
e9/l
0.54
24
174
41
302
1.36
1.10
2.2
2.1
—
—
—
0
0
26
176
1.48
1.10
1.8
1.4
69.9
237.0
pmol/l
0.49
14
55
1112
11645
0.94
1.10
3.4
3.6
5.9
5.9
ph
—
6
8
390
4258
0.91
1.08
6.4
6.6
104.5
104.3
mmol/l
0.56
383
4147
133
1134
1.18
1.07
2.4
2.5
23.8
21.6
s
0.95
117
1022
861
9084
0.93
1.06
2.9
3.0
—
—
—
0
0
27
186
1.45
1.05
1.2
1.2
—
—
—
0
0
28
195
1.44
1.04
1.5
1.5
12.8
13.8
umol/l
0.37
23
185
30
212
1.42
1.03
2.3
2.1
1.6
2.0
ug/l
0.99
23
181
93
772
1.21
1.01
1.5
1.2
61.2
93.8
titre
—
8
63
10
53
1.89
1.01
1.0
1.1
—
—
—
0
0
27
188
1.44
1.01
1.5
1.3
2.9
1.0
u/ml
0.60
18
88
37
275
1.35
0.97
1.2
1.3
1.5
1.5
nmol/l
0.01
32
247
101
1194
0.84
0.95
3.2
3.2
250.4
4277.5
u/ml
1.02
92
1012
65
524
1.24
0.94
1.5
1.4
111.8
117.3
u/ml
0.17
15
90
29
208
1.40
0.94
1.7
2.6
576.8
505.8
e6/l
0.27
24
173
322
3518
0.91
0.93
6.3
7.2
95.0
95.5
%
0.57
312
3369
64
516
1.24
0.93
1.5
1.4
—
—
—
0
0
108
922
1.18
0.89
3.3
3.7
24.3
24.9
mmol/l
0.64
94
806
361
3911
0.91
0.88
5.9
6.9
5.0
5.1
kpa
1.59
341
3711
361
3911
0.91
0.88
5.9
6.9
12.2
12.2
kpa
0.08
340
3714
84
705
1.20
0.85
2.2
2.8
30.2
35.8
umol/l
1.41
64
589
74
614
1.21
0.84
2.7
2.1
8501.4
3375.3
u/l
0.32
30
248
82
688
1.20
0.84
1.6
1.6
5.7
9.3
u/l
4.16
56
541
273
2491
1.10
0.84
3.9
4.0
0.1
0.1
%
0.87
81
707
36
274
1.32
0.83
1.4
1.5
0.3
0.3
nmol/l
0.34
24
209
11
65
1.69
0.82
1.5
1.5
—
—
—
0
0
11
65
1.69
0.82
1.0
1.2
19.7
17.1
umol/l
0.68
11
57
41
319
1.29
0.82
1.4
1.3
627199.6
122773.2
e6/l
0.92
22
219
8
48
1.67
0.78
1.8
1.7
—
—
—
0
0
363
3906
0.92
0.78
5.9
6.9
0.8
1.1
mmol/l
0.91
294
3023
918
8800
1.06
0.77
3.7
3.3
—
—
—
0
0
22
157
1.40
0.76
6.3
6.7
—
—
—
0
0
51
413
1.24
0.75
1.2
1.1
0.3
2.9
u/ml
4.18
17
118
101
873
1.16
0.75
1.1
1.1
—
—
—
0
0
92
790
1.17
0.74
1.1
1.2
—
—
—
0
0
75
884
0.85
0.73
4.6
4.6
7.4
7.4
ph
0.44
70
752
9
55
1.64
0.73
1.4
2.7
—
—
—
0
0
16
108
1.48
0.73
1.1
1.1
1320.5
1614.0
miu/ml
0.61
16
108
99
858
1.16
0.72
1.5
1.3
—
—
—
0
0
284
2621
1.09
0.71
3.9
4.0
0.8
0.9
%
0.20
85
765
36
282
1.28
0.71
1.1
1.2
313.4
346.9
nmol/l
0.43
30
230
89
767
1.16
0.70
1.1
1.1
—
—
—
0
0
79
921
0.85
0.69
1.1
1.2
—
—
—
0
0
13
193
0.67
0.69
1.5
2.1
—
—
—
0
0
42
337
1.25
0.69
3.5
3.5
—
—
—
0
0
753
7863
0.95
0.68
4.0
3.6
—
—
—
0
0
66
557
1.19
0.67
1.6
1.3
235.5
261.2
u/ml
0.29
35
319
77
659
1.17
0.67
1.8
1.9
4.0
4.4
iu/l
0.14
21
215
5
28
1.79
0.66
1.2
1.3
—
—
—
0
0
28
215
1.30
0.65
1.2
1.1
—
—
—
0
0
22
163
1.35
0.64
1.5
1.5
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
8
129
0.62
0.63
1.4
1.3
—
1.4
—
0
9
34
269
1.27
0.63
2.4
1.8
—
1.3
—
0
14
321
2998
1.08
0.62
5.6
6.8
1.3
1.4
mmol/l
0.95
303
2874
312
2911
1.08
0.62
1.7
1.6
—
—
—
0
0
45
369
1.22
0.62
1.2
1.7
—
3.8
—
0
5
27
208
1.30
0.62
1.6
2.3
440.0
698.2
e6/l
2.04
13
79
0
20
0.00
0.60
0.0
1.8
—
21.5
—
0
11
45
371
1.22
0.60
1.8
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
10.9
—
181.6
—
0
15
20
148
1.35
0.59
1.1
1.2
0.6
4.0
u/ml
—
9
70
26
201
1.30
0.58
1.2
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
7
115
0.61
0.57
1.3
1.4
24.1
22.3
%
—
7
105
24
184
1.31
0.57
1.0
1.1
1.4
7.6
nmol/l
—
7
40
43
355
1.21
0.57
2.4
2.5
—
—
—
0
0
51
429
1.19
0.56
1.4
2.1
16.4
25.6
ug/l
1.57
46
423
69
796
0.86
0.56
2.7
2.3
65.3
101.5
ug/min
0.50
39
483
10
65
1.54
0.55
1.1
1.1
—
7.2
pmol/l
—
0
10
37
302
1.23
0.55
1.1
1.1
—
—
—
0
0
34
417
0.81
0.55
3.8
2.5
—
—
—
0
0
12
171
0.70
0.54
2.2
2.3
—
—
—
0
0
51
431
1.19
0.54
1.1
1.1
—
—
—
0
0
8
125
0.64
0.54
1.3
1.5
0.9
2.6
%
—
8
103
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
14
99
1.42
0.54
1.0
1.1
—
—
—
0
0
167
1820
0.91
0.53
8.1
9.5
—
—
—
0
0
64
553
1.16
0.53
4.4
3.3
—
—
—
0
0
15
109
1.38
0.50
1.1
1.2
—
—
—
0
0
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
6
41
1.46
0.50
1.0
1.2
—
—
—
0
0
12
84
1.43
0.49
1.0
1.0
—
—
—
0
0
19
145
1.31
0.48
1.3
1.5
6.0
9.0
ug/l
1.14
19
124
7
109
0.64
0.48
1.0
1.4
—
—
—
0
0
14
189
0.74
0.48
2.2
1.6
—
—
—
0
0
26
208
1.25
0.47
1.1
1.4
—
—
—
0
0
14
102
1.37
0.47
1.1
1.2
0.4
40.8
u/ml
—
9
63
10
68
1.47
0.47
1.2
1.1
—
—
—
0
0
23
288
0.80
0.46
2.3
2.3
3.3
2.0
u/field
—
7
105
70
792
0.88
0.46
2.1
2.2
130.8
128.2
g/l
0.43
49
580
8
118
0.68
0.45
1.1
1.2
—
0.3
—
0
9
18
138
1.31
0.45
1.2
1.1
—
—
—
0
0
7
51
1.37
0.44
1.7
1.5
—
—
—
0
0
68
767
0.88
0.43
1.8
1.9
—
—
—
0
0
13
95
1.37
0.43
1.2
1.5
—
—
—
0
0
90
811
1.11
0.43
1.1
1.1
—
—
—
0
0
31
257
1.21
0.43
1.1
1.2
—
—
—
0
0
29
239
1.22
0.42
5.5
5.0
359.9
39.3
u/ml
0.45
12
63
992
9668
1.04
0.42
4.6
4.0
7.4
7.4
ph
0.12
188
1831
15
114
1.32
0.40
1.5
1.7
—
—
—
0
0
5
34
1.47
0.40
1.8
1.5
—
—
—
0
0
105
959
1.10
0.40
3.2
3.5
—
—
—
0
0
28
232
1.21
0.39
1.2
2.0
7.6
6.7
mmol/l
0.38
21
155
678
6574
1.04
0.39
3.0
2.9
552.5
550.7
mosm/kgh2o
0.07
570
5599
271
2572
1.06
0.38
1.5
1.5
—
—
—
0
0
37
317
1.17
0.37
1.1
1.1
2.7
5.2
u/ml
0.81
23
136
44
383
1.15
0.37
1.5
1.5
—
—
—
0
0
169
1804
0.93
0.37
2.9
2.8
0.4
0.3
e6/l
0.06
164
1765
41
355
1.16
0.37
1.4
1.4
278.7
278.6
mosm/kgh2o
0.01
24
261
34
290
1.17
0.36
1.1
1.1
8.7
6.9
u/ml
0.15
22
132
82
744
1.10
0.36
2.4
2.2
—
—
—
0
0
9
70
1.29
0.36
1.3
1.6
—
—
—
0
0
28
235
1.19
0.36
1.6
1.7
—
—
—
0
0
55
488
1.13
0.36
1.2
1.2
—
—
—
0
0
19
234
0.81
0.35
1.1
1.2
—
260.0
—
0
7
77
698
1.11
0.35
3.4
3.3
443.5
889.2
u/ml
0.41
67
644
33
282
1.17
0.35
1.8
2.6
1.5
1.1
e9/l
0.70
15
172
14
108
1.30
0.35
3.3
2.9
1.6
1.5
ug/l
0.01
14
102
6
43
1.40
0.35
1.0
1.6
—
—
—
0
0
32
273
1.17
0.35
2.3
2.4
—
—
—
0
0
32
273
1.17
0.35
1.2
1.1
1.8
0.4
u/ml
0.36
14
91
17
211
0.80
0.34
1.4
1.3
—
—
—
0
0
42
368
1.14
0.33
1.3
1.2
—
—
—
0
0
26
219
1.19
0.33
1.0
1.0
778.5
679.7
ng/l
0.50
15
139
10
74
1.35
0.32
1.1
1.6
—
—
—
0
0
245
2337
1.05
0.31
4.0
4.0
0.0
0.3
%
0.73
70
586
55
494
1.12
0.31
1.4
1.3
—
—
—
0
0
70
638
1.10
0.30
1.4
1.8
0.8
0.8
nmol/l
0.05
49
522
1016
9968
1.03
0.29
3.9
3.4
113.4
86.0
e6/l
0.25
786
7750
46
411
1.12
0.29
1.2
1.3
—
—
—
0
0
12
94
1.28
0.28
1.5
1.9
—
—
—
0
0
194
1847
1.05
0.28
4.9
4.6
23.8
24.0
mmol/l
0.49
182
1676
68
741
0.92
0.27
2.7
2.5
16.8
16.1
%
0.85
35
389
27
233
1.16
0.27
2.5
2.4
—
—
—
0
0
23
196
1.17
0.27
3.8
3.7
—
—
—
0
0
45
404
1.12
0.26
1.0
1.1
1.5
1.5
g/l
0.55
39
370
12
95
1.26
0.26
1.5
1.7
—
—
—
0
0
12
149
0.80
0.25
1.1
1.2
0.5
16.0
u/ml
—
7
63
204
2130
0.96
0.24
1.5
1.4
—
—
—
0
0
9
76
1.18
0.24
1.1
1.1
—
—
—
0
0
28
318
0.88
0.24
2.2
2.0
—
—
—
0
0
34
303
1.12
0.23
1.4
1.3
—
—
—
0
0
25
218
1.15
0.23
1.0
1.0
213.0
309.2
ng/l
2.08
14
142
5
39
1.28
0.23
1.0
1.5
46.2
42.2
umol/l
—
5
39
19
162
1.17
0.22
1.1
1.2
—
—
—
0
0
73
784
0.93
0.22
1.9
1.9
—
—
—
0
0
19
221
0.86
0.22
1.3
1.3
13.9
12.1
mmol/l
—
10
60
66
612
1.08
0.22
1.5
1.3
—
—
—
0
0
5
41
1.22
0.22
1.2
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
56
606
0.92
0.21
2.1
2.1
—
—
—
0
0
264
2729
0.96
0.21
4.4
3.8
1.2
1.2
mmol/l
0.70
231
2366
57
616
0.92
0.21
4.7
3.7
59.8
57.5
%
0.81
57
616
73
781
0.93
0.21
1.9
2.0
—
—
—
0
0
25
283
0.88
0.21
1.2
1.2
—
—
—
0
0
8
105
0.76
0.21
2.5
2.3
8.9
7.4
%
—
8
99
17
198
0.86
0.20
1.9
2.5
7.4
7.4
ph
—
6
64
10
80
1.25
0.20
1.1
1.1
—
—
—
0
0
74
789
0.94
0.20
4.3
3.9
—
—
—
0
0
691
7033
0.98
0.19
2.9
2.7
5.7
5.1
e6/l
0.45
612
6175
20
174
1.15
0.19
2.3
1.7
0.4
3.6
u/field
—
8
123
6
51
1.18
0.19
1.3
1.9
121.0
145.6
ng/l
—
6
51
1336
13506
0.98
0.19
10.6
10.0
0.0
0.0
e9/l
1.14
1082
10957
45
414
1.09
0.19
1.5
1.4
30918.8
66074.7
e6/l
1.01
30
250
34
374
0.91
0.18
1.4
1.5
—
—
—
0
0
34
374
0.91
0.18
1.4
1.5
—
—
—
0
0
34
374
0.91
0.18
1.4
1.5
—
—
—
0
0
34
374
0.91
0.18
1.4
1.5
—
—
—
0
0
10
81
1.24
0.18
1.3
1.4
—
—
—
0
0
73
776
0.94
0.18
1.9
2.0
—
—
—
0
0
42
386
1.09
0.18
1.4
1.2
—
—
—
0
0
52
483
1.08
0.18
1.1
1.1
26.3
78.8
iu/ml
—
9
109
12
142
0.84
0.17
1.2
1.4
—
67.5
%
—
0
18
29
262
1.11
0.17
1.6
1.3
11.1
13.6
u/l
0.58
29
240
93
978
0.95
0.17
1.5
1.7
—
—
—
0
0
64
681
0.94
0.17
2.9
3.2
—
—
—
0
0
72
761
0.95
0.16
4.5
5.0
2.7
2.8
mmol/l
0.04
47
526
33
360
0.92
0.16
1.4
1.5
—
—
—
0
0
42
389
1.08
0.16
1.6
1.6
—
—
—
0
0
56
526
1.07
0.15
2.6
2.7
—
—
—
0
0
25
276
0.91
0.15
2.2
4.1
11.5
11.1
%
0.27
25
276
14
121
1.16
0.15
2.5
2.7
50.8
120.2
umol/l
—
8
72
9
82
1.10
0.15
1.3
1.1
—
—
—
0
0
9
83
1.08
0.14
1.7
1.3
—
—
—
0
0
188
1826
1.03
0.14
1.6
1.6
—
—
—
0
0
10
118
0.85
0.14
4.8
4.3
44.2
54.2
%
—
10
113
8
99
0.81
0.13
2.5
2.3
—
—
—
0
0
60
568
1.06
0.13
1.3
1.2
48.4
45.4
u/l
0.04
48
491
27
247
1.09
0.13
1.3
1.2
—
—
—
0
0
641
6494
0.98
0.13
3.9
3.9
495.3
560.8
ng/l
0.13
510
5362
208
2131
0.97
0.12
3.5
3.2
—
—
—
0
0
48
454
1.06
0.11
1.5
1.5
3023.1
1966.1
e6/l
0.29
39
330
295
3006
0.98
0.11
8.1
7.9
—
—
—
0
0
918
9098
1.01
0.11
3.8
3.3
0.5
0.5
e6/l
0.01
695
6940
45
426
1.06
0.10
3.5
2.4
25.8
1070.1
u/ml
0.87
45
408
69
718
0.96
0.10
3.0
3.5
—
—
—
0
0
25
269
0.93
0.10
2.8
2.2
670.4
624.9
ml
0.19
15
166
13
116
1.12
0.09
3.1
2.3
—
—
—
0
0
63
655
0.96
0.09
1.8
1.7
4.7
24.3
e6/l
1.40
45
510
63
655
0.96
0.09
1.8
1.8
1024.8
680.2
e6/l
0.25
48
536
1152
11447
1.01
0.09
4.4
3.9
77.7
114.3
e6/l
1.44
832
8260
188
1843
1.02
0.09
1.3
1.4
—
—
—
0
0
6
55
1.09
0.08
5.7
6.7
123.2
66.6
g/mol
—
6
47
10
88
1.14
0.08
2.1
1.9
—
—
—
0
0
7
66
1.06
0.08
1.4
1.4
33.3
26.5
g/l
—
7
53
6
71
0.84
0.07
1.2
1.5
—
—
—
0
0
40
382
1.05
0.07
1.2
1.3
—
—
—
0
0
38
363
1.05
0.07
1.1
1.1
—
—
—
0
0
15
163
0.92
0.07
1.2
1.3
—
—
—
0
0
70
721
0.97
0.07
1.9
2.0
—
—
—
0
0
8
91
0.88
0.06
1.1
1.1
—
—
—
0
0
8
93
0.86
0.06
1.0
1.0
—
—
—
0
0
14
128
1.09
0.06
2.6
1.7
3.4
9.1
nmol/l
—
9
108
19
177
1.07
0.06
1.0
1.0
—
—
—
0
0
11
99
1.11
0.06
1.3
1.1
—
—
—
0
0
27
284
0.95
0.06
1.3
1.4
—
—
—
0
0
38
365
1.04
0.06
1.1
1.1
—
—
—
0
0
28
293
0.96
0.05
2.1
1.4
39.3
27.3
%
0.59
15
183
36
373
0.96
0.04
1.5
1.3
200.5
275.8
pmol/l
1.90
27
279
126
1241
1.02
0.04
1.5
1.4
—
—
—
0
0
790
7935
0.99
0.04
6.5
6.7
—
—
—
0
0
13
121
1.07
0.03
2.4
2.3
57.1
74.6
ug/l
0.45
13
116
23
220
1.05
0.03
1.1
1.1
—
—
—
0
0
30
290
1.03
0.03
1.3
1.2
—
—
—
0
0
61
599
1.02
0.02
1.4
1.5
—
—
—
0
0
28
289
0.97
0.02
2.8
3.2
85.9
27.2
mg/l
0.43
20
224
36
352
1.02
0.01
2.5
2.0
—
—
—
0
0
28
286
0.98
0.00
1.3
1.4
—
—
—
0
0
11
108
1.02
0.00
1.1
1.1
—
—
—
0
0
19
188
1.01
0.00
2.9
2.0
502.4
492.5
min
0.19
11
134
12
115
1.04
0.00
2.3
2.4
—
—
—
0
0
19
185
1.03
0.00
1.4
1.5
—
—
—
0
0
38
375
1.01
0.00
1.3
1.2
5.3
5.1
u/ml
0.02
19
169
132
1318
1.00
0.00
4.4
3.5
28.9
68.5
u/ml
5.18
124
1266
26
259
1.00
0.00
2.7
2.3
—
—
—
0
0
40
404
0.99
0.00
1.7
1.4
144.6
54.9
mu/l
0.60
30
353
29
293
0.99
0.00
1.3
1.5
—
—
—
0
0
73
727
1.00
0.00
1.2
1.2
—
—
—
0
0
22
217
1.01
0.00
2.0
2.7
18.8
13.0
%
0.48
13
114
13
133
0.98
0.00
1.2
1.2
362.6
217.5
iu/ml
0.55
13
133
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
1.6
—
0
5
5
49
1.02
0.00
3.6
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1270.0
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
0.00
1.4
1.4
26.4
36.0
nmol/l
—
7
57
8
86
0.93
0.00
1.5
1.5
—
—
—
0
0
9
91
0.99
0.00
1.2
1.2
—
21.4
%
—
0
12
5
49
1.02
0.00
7.2
5.1
—
—
—
0
0
6
68
0.88
0.00
1.0
1.0
—
—
—
0
0
8
81
0.99
0.00
6.0
4.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
6
60
1.00
0.00
1.2
1.6
—
—
—
0
0
5
53
0.94
0.00
3.4
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
8
86
0.93
0.00
1.3
2.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_CERUMEN and mortality.

Females

Parameter HR [95% CI] p-value
H8_CERUMEN 1.112 [0.97, 1.27] 0.114
Birth year 0.996 [0.99, 1.0] 0.302

During the follow-up period (1.1.1998 — 31.12.2019), 1825 out of 8627 females with H8_CERUMEN died.

Males

Parameter HR [95% CI] p-value
H8_CERUMEN 1.225 [1.06, 1.42] 0.006
Birth year 0.989 [0.98, 1.0] 0.02

During the follow-up period (1.1.1998 — 31.12.2019), 1919 out of 8943 males with H8_CERUMEN died.

Mortality risk

Mortality risk for people of age

years, who have H8_CERUMEN.

N-year risk Females Males
1 0.092% 0.232%
5 0.661% 1.536%
10 1.651% 3.767%
15 3.381% 7.112%
20 5.82% 11.886%

Relationships between endpoints

Index endpoint: H8_CERUMEN – Impacted cerumen

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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