≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Complex cardiac defects

Endpoint Browser PheWeb

Q17_COMPLEX_CARD_DEFEC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q2040|Q2041|Q2048|Q205|Q2060|Q2061|Q208|Q209|Q2115|Q2180|Q225|Q242|Q2521|Q2544
  • Hospital discharge: ICD-9 — 7453B|7451C|7458X|7459X|7456X|7454C|7462A|7468A|7471C|7472X
  • Hospital discharge: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Hospital discharge: excluded ICD-9 — 758|7595|75683
  • Cause of death: ICD-10 — Q2040|Q2041|Q2048|Q205|Q2060|Q2061|Q208|Q209|Q2115|Q2180|Q225|Q242|Q2521|Q2544
  • Cause of death: ICD-9 — 7453B|7451C|7458X|7459X|7456X|7454C|7462A|7468A|7471C|7472X
  • Cause of death: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Cause of death: excluded ICD-9 — 758|7595|75683

2 out of 7 registries used, show all original rules.

220

4. Check minimum number of events

None

220

5. Include endpoints

None

220

6. Filter based on genotype QC (FinnGen only)

205

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2105 1054 1036
Only index persons 1452 753 699
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 5.92 8.36 2.74
Only index persons 11.17 16.28 5.66

-FinnGen-

Key figures

All Female Male
Number of individuals 205 116 89
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 14.28 19.01 8.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
220
Matched controls
2200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
201
Kela drug reimbursment
Chronic cardiac insufficiency
100.8
204.0
111
22
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
36.3
148.7
109
58
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
44.4
144.8
95
37
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
24.9
136.5
139
142
B01AA03
ATC
warfarin; systemic
27.6
131.8
110
77
XF404
NOMESCO Finland
Ambulatory ECG
26.5
124.7
104
72
C03DA01
ATC
spironolactone; oral
24.9
117.0
99
70
C01AA05
ATC
digoxin; systemic
56.2
113.7
67
17
XF402
NOMESCO Finland
ECG with work load test
27.6
110.9
86
50
C03CA01
ATC
furosemide; systemic
15.9
99.1
125
168
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
49.7
93.1
56
15
XF400
NOMESCO Finland
ECG with 12 standard connections
12.8
83.6
123
198
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
36.1
70.5
46
16
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.2
69.4
81
93
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
32.0
67.7
46
18
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
21.5
65.6
53
32
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
9.3
62.6
120
252
ZXE20
NOMESCO Finland
More than three and less than five hours
10.2
62.4
95
153
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
33.4
61.5
41
15
Q20.48
ICD-10 Finland
Single ventricle
+∞
57.9
53
*
TPH07
NOMESCO Finland
Cathetrisation of artery
9.9
55.1
80
120
Q22.5
ICD-10 Finland
Ebstein anomaly
+∞
53.3
49
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
8.6
53.1
93
173
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
329.8
52.5
51
*
FM2CE, ,
NOMESCO Finland
14.0
52.5
54
50
TFP20
NOMESCO Finland
Cardiodefibrillation
20.1
49.1
40
24
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
9.0
47.2
72
113
Z2221
NOMESCO Finland
Medical doctor
6.8
45.1
137
429
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.1
45.0
151
517
Q21.10
ICD-10 Finland
Persistent ostium secundum
18.3
43.6
37
24
I48
ICD-10 Finland
Atrial fibrillation and flutter
9.7
43.4
59
80
ZXD10
NOMESCO Finland
Scheduled procedure
6.6
41.6
150
538
ZXE30
NOMESCO Finland
More than five and less than seven hours
11.2
41.5
49
55
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
162.0
39.2
40
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
68.2
39.0
44
8
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
66.3
38.0
43
8
31
HP
Congenital heart failure surgery
96.8
37.2
40
5
61
HP
Catheterization and pressure measurement of the left side of the heart
80.9
36.4
40
6
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
57.3
36.2
42
9
ZXE10
NOMESCO Finland
More than one and less than three hours
5.6
35.7
134
481
207
Kela drug reimbursment
Chronic arrhythmias
9.2
34.5
47
63
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
88.2
34.0
37
5
62
HP
Catheterization and pressure measurement of the right side of the heart
138.0
33.8
35
*
WX408
NOMESCO Finland
General anesthesy, balanced
5.3
33.7
115
378
R4110
NOMESCO Finland
Physiotherapy
5.3
33.6
118
397
G04BE03
ATC
sildenafil; oral
186.2
31.6
32
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
7.6
30.3
49
80
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
8.7
29.9
42
58
C01BD01
ATC
amiodarone; systemic
93.3
29.6
32
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
93.3
29.6
32
*
XF600
NOMESCO Finland
Bloodpressure measurement
6.7
29.0
54
102
WX892
NOMESCO Finland
Monitored bed care
7.0
26.1
45
78
I50.9
ICD-10 Finland
Heart failure, unspecified
8.6
25.8
36
49
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.4
25.6
95
321
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
25.5
24
*
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
+∞
24.4
23
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
53.1
24.0
28
6
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
53.1
24.0
28
6
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
23.3
22
*
XF620
NOMESCO Finland
Examination of circulation with color method
70.1
22.4
25
*
C09AA02
ATC
enalapril; systemic
5.7
22.3
48
103
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
22.3
21
*
WX872
NOMESCO Finland
Intensive care
20.2
22.1
33
19
ZXD05
NOMESCO Finland
Urgent procedure
3.9
21.6
104
414
ZXE00
NOMESCO Finland
One hour or less
3.8
21.2
134
637
Q25.1
ICD-10 Finland
Coarctation of aorta
32.5
20.2
26
9
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
+∞
20.1
19
*
Q20.1
ICD-10 Finland
Double outlet right ventricle
218.9
19.9
20
*
Z3231
NOMESCO Finland
Registered nurse
3.6
19.4
113
502
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.5
19.1
26
34
I47.1
ICD-10 Finland
Supraventricular tachycardia
8.2
19.1
27
37
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
109.5
18.9
20
*
WX882
NOMESCO Finland
High dependency care
5.6
18.9
40
84
Q21.21
ICD-10 Finland
Atrioventricular duct
206.9
18.8
19
*
C07AA07
ATC
sotalol; systemic
28.0
18.7
25
10
C07AB07
ATC
bisoprolol; oral
3.6
18.6
93
373
I44.2
ICD-10 Finland
Atrioventricular block, complete
36.4
18.4
23
7
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
57.7
18.3
21
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
57.7
18.3
21
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
18.0
17
*
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
31.9
17.8
23
8
ZX120
NOMESCO Finland
Intravenous
4.7
17.0
45
114
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
16.9
16
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
183.3
16.7
17
*
WX704
NOMESCO Finland
Intubation
5.5
16.0
34
71
Z98.8
ICD-10 Finland
Other specified postsurgical states
28.8
15.9
21
8
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.8
15.9
61
203
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
171.7
15.7
16
*
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
171.7
15.7
16
*
7AX01, ,
NOMESCO Finland
48.8
15.3
18
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
48.8
15.3
18
*
C07AB02
ATC
metoprolol; systemic
4.2
15.0
47
135
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
61.1
15.0
17
*
Z3226
NOMESCO Finland
Physiotherapist
3.3
14.8
78
316
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
14.7
14
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
14.7
14
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
14.7
62
219
B01AB05
ATC
enoxaparin; parenteral
3.4
14.5
66
244
I50.1
ICD-10 Finland
Left ventricular failure
29.5
14.5
19
7
Z2446
NOMESCO Finland
Social worker
3.8
14.2
52
167
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
57.2
14.0
16
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
6.4
13.8
24
41
XFE00
NOMESCO Finland
Epicardial ultrasonography
17.7
13.8
21
13
Z94.1
ICD-10 Finland
Heart transplant status
80.3
13.8
15
*
Q20.9
ICD-10 Finland
Congenital malformation of cardiac chambers and connections, unspecified
+∞
13.7
13
*
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
13.7
13
*
XF640, ,
NOMESCO Finland
15.3
13.1
21
15
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
53.3
13.0
15
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
12.8
61
231
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
34.3
12.8
16
5
I50.0
ICD-10 Finland
Congestive heart failure
14.4
12.7
21
16
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
26.2
12.7
17
7
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
12.7
12.6
22
19
7453B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Common ventricle[COMMON VENTRICLE]
+∞
12.6
12
*
Q24.0
ICD-10 Finland
Dextrocardia
137.5
12.6
13
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
137.5
12.6
13
*
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
6.3
12.5
22
38
I49.5
ICD-10 Finland
Sick sinus syndrome
17.2
12.4
19
12
Q25.0
ICD-10 Finland
Patent ductus arteriosus
13.6
11.9
20
16
ZX108
NOMESCO Finland
Inhalation
20.3
11.8
17
9
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
68.7
11.7
13
*
602
Kela drug reimbursment
Children's severe malnutrition
6.2
11.7
21
37
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
+∞
11.6
11
*
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
11.6
11
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
+∞
11.6
11
*
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
+∞
11.6
11
*
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
37.2
11.4
14
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
26.7
11.3
15
6
Q21.19
ICD-10 Finland
Atrial septal defect NOS
26.7
11.3
15
6
WX402
NOMESCO Finland
General anaesthesia
2.8
11.2
76
348
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
22.9
10.8
15
7
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
8.4
10.7
23
30
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
115.3
10.5
11
*
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
10.5
10
*
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
+∞
10.5
10
*
AP2
HP
Catheterization of the right side of the heart
+∞
10.5
10
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
10.4
60
251
ZX199
NOMESCO Finland
Other rote
15.6
10.2
16
11
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
57.6
9.7
11
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
57.6
9.7
11
*
C09AA05
ATC
ramipril; oral
3.4
9.6
38
127
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.3
9.5
20
41
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
11.4
9.5
17
16
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
9.4
9
*
Q20.00
ICD-10 Finland
Common arterial trunk
+∞
9.4
9
*
FGB10
NOMESCO Finland
Repair of Ebstein's anomaly with mobilisation and ventricular plication
+∞
9.4
9
*
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
9.4
9
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
9.4
9
*
7454C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[LEFT VENTRICULAR AND RIGHT ATRIAL COMMUNICATION]
+∞
9.4
9
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
9.3
60
265
I44.1
ICD-10 Finland
Atrioventricular block, second degree
38.4
9.1
11
*
TFJ02
NOMESCO Finland
Muscle biopsy of heart
38.4
9.1
11
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
25.2
9.0
12
5
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.5
8.8
33
106
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
8.8
8.8
18
22
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.4
8.6
83
442
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.5
8.5
32
103
81
HP
Angiography of the heart and coronary arteries
13.5
8.5
14
11
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
93.5
8.5
9
*
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
93.5
8.5
9
*
7461A
ICD-9 Finland
Other congenital anomalies of heart, Tricuspid atresia and stenosis, congenital[VITIUM VALVULAE TRICUSPIDALIS CONGENITUM CUM ATRESI]
+∞
8.4
8
*
FFK20
NOMESCO Finland
Atrio-pulmonary anastomosis
+∞
8.4
8
*
Q21.88
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
8.4
8
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
+∞
8.4
8
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
8.4
8
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
8.4
8
*
Q20.4
ICD-10 Finland
Double inlet ventricle
+∞
8.4
8
*
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
+∞
8.4
8
*
Q21.8
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
8.4
8
*
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
+∞
8.4
8
*
K84
ICPC
Heart disease other
18.0
8.2
12
7
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
34.7
8.1
10
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.7
8.1
19
43
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
13.7
8.0
13
10
RS224, ,
NOMESCO Finland
10.0
7.9
15
16
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
11.4
7.9
14
13
AN1
HP
Coronary angiography
4.6
7.9
19
44
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
46.7
7.8
9
*
I48.4
ICD-10 Finland
Atypical atrial flutter
46.7
7.8
9
*
GD1LA
NOMESCO Finland
GD
46.7
7.8
9
*
Q23.11
ICD-10 Finland
Bicuspid aortic valve
12.5
7.7
13
11
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
12.5
7.7
13
11
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
10.6
7.6
14
14
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
26.0
7.6
10
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
26.0
7.6
10
*
K83
ICPC
Heart valve disease NOS
26.0
7.6
10
*
FM1BD
NOMESCO Finland
Extensive CT of heart
26.0
7.6
10
*
127
Kela drug reimbursment
Transplant complication
6.9
7.6
18
28
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
8.1
7.5
16
21
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
3.6
7.5
26
79
7460B
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITUM CUM ATRESIA]
+∞
7.3
7
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
7.3
7
*
5233
FHL
Right ventricular bypass surgery (Fontan et al.)
+∞
7.3
7
*
Q20.41
ICD-10 Finland
Double inlet right ventricle
+∞
7.3
7
*
7459X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Unspecified defect of septal closure
+∞
7.3
7
*
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
7.3
7
*
5409
FHL
Other measure in this category
+∞
7.3
7
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.5
7.2
26
81
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
31.1
7.2
9
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
31.1
7.2
9
*
Q21.0
ICD-10 Finland
Ventricular septal defect
20.8
7.2
10
5
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
7.2
55
261
WZC30
NOMESCO Finland
Teaching
2.8
7.1
40
163
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.6
6.9
24
73
R18
ICD-10 Finland
Ascites
17.4
6.8
10
6
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
41.4
6.8
8
*
L04AA06
ATC
mycophenolic acid; systemic
6.8
6.8
16
25
FL1AC
NOMESCO Finland
Left cardioangiography
23.3
6.7
9
*
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
23.3
6.7
9
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
23.3
6.7
9
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
6.7
27
91
73
HP
Initial pacemaker installation
71.8
6.5
7
*
1EA01, ,
NOMESCO Finland
71.8
6.5
7
*
AP3
HP
Catheterization of the right and left side of the heart
71.8
6.5
7
*
AF1
HP
Surgery of congenital heart defect
71.8
6.5
7
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
71.8
6.5
7
*
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
71.8
6.5
7
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
6.4
52
252
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
6.4
29
104
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
6.3
6.4
16
27
R04.0
ICD-10 Finland
Epistaxis
4.1
6.4
18
47
F81.0
ICD-10 Finland
Specific reading disorder
9.7
6.4
12
13
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
3.9
6.3
19
52
L04AD02
ATC
tacrolimus; systemic
7.4
6.3
14
20
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
18.7
6.3
9
5
FK1AC
NOMESCO Finland
Right cardioangiography
+∞
6.3
6
*
Q21.15
ICD-10 Finland
Common atrium
+∞
6.3
6
*
Q22.6
ICD-10 Finland
Hypoplastic right heart syndrome
+∞
6.3
6
*
7462A
ICD-9 Finland
Other congenital anomalies of heart, Ebstein's anomaly[ANOMALIA EBSTEIN]
+∞
6.3
6
*
51
HP
Other heart surgery
+∞
6.3
6
*
74637
ICD-8 Finland
Congenital anomalies of heart, Cor triloculare biatriatum (""""single ventricles"""")
+∞
6.3
6
*
5401
FHL
Pacemaker installation, transvenous electrode
+∞
6.3
6
*
4260A
ICD-9 Finland
Conduction disorders, Atrioventricular block, complete
+∞
6.3
6
*
1CX08, ,
NOMESCO Finland
+∞
6.3
6
*
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
+∞
6.3
6
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
27.5
6.3
8
*
5253
FHL
Cardiac lung machine
27.5
6.3
8
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
27.5
6.3
8
*
J01DA06
ATC
[U] cefuroxime
2.8
6.1
34
137
C02EA02, ,
ATC
10.5
6.1
11
11

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
166
263
22.64
120.59
11.1
3.6
756.23
786.78
ng/l
0.09
161
220
104
223
7.95
51.85
7.0
3.0
2944.18
513.12
ng/l
1.24
89
133
153
529
7.21
45.19
33.3
8.3
1.85
1.11
inr
5.46
33
165
85
209
6.00
35.15
3.8
2.7
19.71
23.47
%
1.79
76
191
109
381
4.69
28.65
4.1
2.9
—
—
—
0
0
66
163
5.36
26.44
14.6
11.4
106.35
104.79
mmol/l
1.77
66
163
39
60
7.69
25.21
37.6
19.7
—
—
—
0
0
120
493
4.15
24.46
4.3
3.0
—
—
—
0
0
38
59
7.58
24.33
40.6
12.5
24.48
24.45
mmol/l
0.02
38
59
97
358
4.06
22.72
6.3
3.5
1.81
0.98
mg/l
1.58
77
271
26
33
8.80
19.58
6.5
26.2
—
—
—
0
0
124
617
3.31
17.14
11.5
7.4
37.45
37.30
g/l
0.09
119
582
48
129
4.48
16.84
33.4
12.5
0.85
1.22
mmol/l
0.27
43
105
36
77
5.39
16.55
42.9
10.9
1.05
1.28
%
1.36
36
77
36
77
5.39
16.55
42.9
10.9
0.69
0.71
%
0.11
36
77
23
32
7.91
15.99
7.2
23.1
73.26
72.32
%
0.08
23
32
134
724
3.18
15.63
4.7
3.0
—
—
—
0
0
159
963
3.35
14.95
6.6
3.0
—
—
—
0
0
58
202
3.54
13.98
2.7
2.1
—
—
—
0
0
67
257
3.31
13.84
30.2
10.3
—
—
—
0
0
90
426
2.88
12.71
5.1
3.4
60.26
18.52
ng/l
1.26
54
218
66
274
3.01
11.71
9.2
10.4
0.98
1.17
mmol/l
0.20
56
216
150
965
2.74
11.07
18.3
6.9
6.11
6.30
mmol/l
0.75
145
890
85
419
2.68
10.79
4.1
3.3
3.76
2.82
mg/l
0.85
79
366
64
273
2.90
10.72
27.8
13.8
24.91
25.14
mmol/l
0.30
64
273
73
336
2.75
10.57
6.9
5.0
—
—
—
0
0
53
209
3.02
10.17
2.5
1.7
—
—
—
0
0
99
559
2.40
9.10
8.6
9.6
—
—
—
0
0
128
813
2.37
8.94
20.6
11.2
1.20
1.22
mmol/l
2.51
119
731
26
71
4.02
8.74
7.6
13.3
0.75
0.70
%
0.26
26
71
53
227
2.76
8.65
17.4
8.5
—
—
—
0
0
127
821
2.29
8.28
4.5
3.1
97.50
79.68
ug/l
0.51
121
767
11
5
23.03
8.10
3.6
1.8
—
—
—
0
0
18
40
4.81
7.80
1.2
1.2
5.00
2.80
u/ml
—
10
20
56
259
2.56
7.78
17.6
9.0
5.00
5.04
kpa
0.21
56
246
41
162
2.88
7.73
2.0
1.6
—
—
—
0
0
13
13
10.54
7.13
5.2
2.7
—
—
—
0
0
12
11
11.46
6.88
3.5
12.4
—
—
—
0
0
12
11
11.46
6.88
3.5
12.4
—
—
—
0
0
19
50
4.06
6.69
3.8
2.7
—
—
—
0
0
15
23
6.92
6.46
9.5
31.0
11.31
12.09
%
0.45
15
23
47
218
2.47
6.41
18.2
8.6
8.71
9.66
kpa
2.05
47
208
66
357
2.21
6.32
4.2
2.3
430.73
165.02
u/l
1.61
66
347
135
955
2.07
6.31
10.6
9.2
—
—
—
0
0
13
17
8.05
6.22
4.8
3.4
1.20
2.44
%
—
5
9
16
40
4.24
6.01
3.0
2.6
—
—
—
0
0
139
1009
2.03
5.87
10.3
8.6
0.60
0.56
e9/l
0.72
129
857
139
1010
2.02
5.84
10.3
8.6
0.04
0.04
e9/l
0.10
129
855
14
24
6.15
5.63
3.9
2.2
—
—
—
0
0
141
1041
1.99
5.53
11.5
9.5
0.17
0.20
e9/l
1.30
132
903
12
18
6.98
5.33
1.0
1.0
—
—
—
0
0
12
18
6.98
5.33
1.0
1.2
—
—
—
0
0
13
23
5.94
5.15
4.1
2.3
—
—
—
0
0
79
495
1.93
4.92
3.9
3.2
2.39
2.37
mmol/l
0.44
73
452
70
421
1.97
4.91
5.4
3.9
7.38
7.40
ph
1.73
14
76
139
1048
1.89
4.82
10.3
8.5
1.67
2.14
e9/l
6.77
129
914
82
527
1.89
4.69
4.0
3.8
29.68
39.46
e6/l
0.24
62
406
129
957
1.84
4.64
13.2
11.2
0.00
0.01
e9/l
0.44
109
735
9
11
8.47
4.60
1.0
1.2
—
—
—
0
0
52
290
2.04
4.46
2.7
3.8
2.68
2.48
e6/l
0.07
28
172
9
12
7.76
4.40
1.2
1.5
13.67
10.33
umol/l
—
9
12
7
6
11.99
4.30
2.0
1.2
—
—
—
0
0
75
481
1.85
4.25
4.1
3.8
0.38
0.20
e6/l
0.63
55
366
91
622
1.79
4.17
4.8
4.6
9.81
49.54
e6/l
2.38
63
427
14
36
4.08
4.08
1.6
1.3
—
—
—
0
0
75
487
1.82
4.05
4.0
3.8
—
—
—
0
0
32
154
2.26
3.97
6.2
4.4
69.59
65.96
e9/l
0.14
19
106
56
337
1.89
3.82
4.0
3.1
622.06
578.22
mosm/kgh2o
0.71
51
288
6
5
12.28
3.78
1.8
1.2
—
—
—
0
0
195
1712
2.22
3.59
36.4
16.4
14.17
13.94
%
0.40
195
1687
12
31
4.03
3.55
2.0
2.7
2.04
2.23
ug/l
0.05
12
26
206
1862
2.67
3.35
22.2
10.3
—
—
—
0
0
33
571
0.50
3.33
2.5
2.3
—
—
—
0
0
50
303
1.84
3.31
7.4
3.2
—
—
—
0
0
6
7
8.77
3.28
1.8
2.4
—
—
—
0
0
141
1138
1.67
3.22
13.0
11.8
3.76
3.77
e9/l
0.01
130
973
201
1804
2.32
3.20
26.5
12.4
24.58
21.09
mg/l
0.91
167
1305
82
581
1.66
3.12
1.6
1.6
—
—
—
0
0
5
172
0.27
2.99
1.8
1.8
—
—
—
0
0
20
93
2.27
2.70
1.5
1.2
—
—
—
0
0
16
67
2.50
2.70
3.7
11.6
—
—
—
0
0
12
41
3.04
2.66
1.3
3.5
0.87
1.53
e9/l
—
7
31
13
52
2.59
2.40
1.3
1.2
—
—
—
0
0
5
8
6.36
2.38
1.2
1.5
—
—
—
0
0
11
39
2.91
2.38
1.3
3.3
0.27
0.19
e9/l
—
5
29
7
17
4.22
2.38
1.1
2.0
—
—
—
0
0
29
167
1.85
2.25
1.4
1.6
—
—
—
0
0
30
175
1.83
2.24
1.3
1.2
—
—
—
0
0
135
1143
1.47
2.02
5.1
4.4
—
—
—
0
0
9
32
2.89
2.02
2.8
4.1
—
—
—
0
0
5
11
4.62
1.95
1.4
1.1
—
—
—
0
0
32
202
1.68
1.84
1.8
2.5
2.44
2.44
mmol/l
0.12
26
170
21
119
1.85
1.73
3.6
1.6
—
—
—
0
0
10
40
2.57
1.69
1.3
3.3
265.20
502.90
e6/l
—
5
29
28
175
1.69
1.68
1.4
1.6
1045.00
1133.77
nmol/l
0.15
22
131
8
31
2.64
1.67
1.1
1.2
—
—
—
0
0
42
292
1.54
1.65
1.6
1.6
—
—
—
0
0
52
381
1.48
1.60
3.2
3.7
—
—
—
0
0
5
129
0.37
1.54
1.0
1.3
—
—
—
0
0
21
124
1.77
1.53
2.9
5.7
0.19
0.56
%
—
8
43
5
15
3.38
1.53
1.6
1.3
—
—
—
0
0
47
627
0.68
1.53
1.6
1.6
0.38
1.83
u/ml
—
5
127
60
463
1.41
1.40
2.0
1.7
86.66
101.35
pmol/l
1.30
32
229
6
24
2.54
1.31
5.5
4.6
22.83
27.17
umol/l
—
6
24
9
44
2.09
1.28
1.3
1.3
—
—
—
0
0
8
35
2.33
1.28
6.5
19.5
1.12
1.07
mmol/l
—
8
30
6
25
2.44
1.25
1.2
2.1
—
—
—
0
0
8
37
2.21
1.23
3.0
4.0
20.95
15.74
u/ml
—
8
37
20
125
1.66
1.22
3.6
6.1
0.00
0.23
%
—
8
39
25
166
1.57
1.21
2.0
1.8
—
—
—
0
0
33
452
0.68
1.21
3.4
3.0
—
—
—
0
0
8
38
2.15
1.19
1.8
1.7
—
—
—
0
0
6
26
2.34
1.19
1.0
1.0
—
—
—
0
0
5
111
0.44
1.16
1.4
1.6
294.00
318.43
mu/l
—
5
105
21
135
1.61
1.16
3.6
5.9
0.72
0.72
%
—
9
50
7
30
2.38
1.13
1.1
1.0
—
—
—
0
0
7
32
2.23
1.09
1.7
4.9
64.71
55.62
%
—
7
32
7
32
2.23
1.09
1.9
4.8
5.81
4.23
e9/l
—
7
32
10
52
1.97
1.08
1.2
2.1
—
—
—
0
0
55
437
1.34
1.07
3.2
2.8
—
—
—
0
0
16
98
1.68
1.06
3.6
4.7
1.25
1.23
mmol/l
0.78
16
88
5
22
2.30
1.04
10.4
2.3
1.44
1.25
mmol/l
—
5
22
16
99
1.66
1.03
3.3
1.7
—
—
—
0
0
31
414
0.71
0.99
1.7
1.8
—
—
—
0
0
64
527
1.30
0.97
1.7
2.1
—
—
—
0
0
12
70
1.76
0.94
2.3
2.2
—
—
—
0
0
11
182
0.58
0.94
2.8
1.5
—
—
—
0
0
6
27
2.26
0.94
3.8
4.8
—
—
—
0
0
10
169
0.57
0.93
2.8
1.6
—
—
—
0
0
11
181
0.59
0.92
2.6
1.5
—
—
—
0
0
6
28
2.17
0.92
3.5
3.8
8.93
8.56
kpa
—
6
28
6
28
2.17
0.92
3.5
3.8
4.57
5.00
kpa
—
6
28
6
29
2.10
0.90
1.0
1.0
153.67
163.83
g/l
—
6
29
11
179
0.59
0.89
2.7
1.6
—
—
—
0
0
11
179
0.59
0.89
2.6
1.6
—
—
—
0
0
51
412
1.31
0.88
1.6
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
12.5
—
760.25
—
0
24
0
27
0.00
0.78
0.0
1.5
—
2.42
—
0
27
6
34
1.79
0.77
3.5
3.5
7.41
7.42
ph
—
6
28
20
274
0.70
0.75
1.3
1.2
4.77
7.87
u/ml
—
6
119
5
24
2.11
0.75
3.0
1.7
16693.80
7501.76
e6/l
—
5
17
16
228
0.68
0.74
1.1
1.3
—
—
—
0
0
10
60
1.70
0.73
1.6
1.6
—
—
—
0
0
9
142
0.62
0.72
3.0
1.6
—
—
—
0
0
7
118
0.58
0.70
4.7
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
8.2
—
38.40
—
0
5
8
54
1.50
0.58
4.5
6.1
—
—
—
0
0
124
1148
1.18
0.58
6.1
3.8
67.03
35.66
u/l
3.38
119
1092
13
90
1.47
0.57
2.2
1.3
—
—
—
0
0
211
2068
1.50
0.53
47.5
18.4
40.37
40.37
%
0.00
203
1990
26
319
0.79
0.49
1.4
1.8
—
—
—
0
0
5
81
0.61
0.46
3.2
1.9
—
—
—
0
0
21
167
1.28
0.43
1.3
1.4
55.39
354.33
u/ml
1.38
21
156
5
33
1.53
0.41
2.4
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
205.16
—
0
16
10
71
1.43
0.40
1.3
1.2
—
—
—
0
0
5
36
1.40
0.38
1.8
3.5
3.86
3.92
mmol/l
—
5
36
5
36
1.40
0.38
6.2
6.6
—
—
—
0
0
21
171
1.25
0.37
1.4
1.4
—
—
—
0
0
5
76
0.65
0.36
1.2
1.5
—
—
—
0
0
21
254
0.81
0.36
1.3
1.2
—
—
—
0
0
6
41
1.48
0.36
2.3
1.2
—
—
—
0
0
12
156
0.76
0.36
1.3
1.4
167.18
150.60
iu/ml
—
6
57
6
42
1.44
0.36
5.0
3.2
77.00
3186.95
u/ml
—
6
37
24
285
0.82
0.35
1.2
1.2
11.33
18.28
iu/ml
—
7
85
126
1314
0.90
0.28
4.4
4.2
37.41
37.68
mmol/mol
0.12
117
1243
8
63
1.28
0.28
1.9
1.5
—
—
—
0
0
5
72
0.69
0.26
1.2
1.4
—
—
—
0
0
5
72
0.69
0.26
1.2
1.4
—
—
—
0
0
29
257
1.15
0.23
1.5
1.5
265.00
438.33
titre
—
8
48
5
38
1.32
0.23
2.4
1.5
0.18
0.29
nmol/l
—
5
28
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
1425.82
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
8.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
7.25
—
0
13
0
13
0.00
0.21
0.0
27.7
—
0.60
—
0
13
0
13
0.00
0.21
0.0
1.3
—
21.40
—
0
5
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
0
14
0.00
0.20
0.0
5.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
8.6
—
0.63
—
0
14
7
62
1.13
0.17
1.3
1.1
—
—
—
0
0
13
152
0.85
0.17
1.5
1.5
—
—
—
0
0
7
63
1.11
0.17
1.0
1.2
—
—
—
0
0
7
63
1.11
0.17
1.3
1.1
—
—
—
0
0
13
113
1.16
0.13
1.2
1.3
—
36.45
—
0
8
145
1475
0.95
0.10
3.9
3.5
1.32
1.45
mmol/l
3.41
139
1385
83
805
1.05
0.10
3.5
3.6
0.00
0.00
estimate
-0.00
16
164
13
116
1.13
0.09
1.1
1.0
—
—
—
0
0
11
97
1.14
0.09
9.1
5.5
—
—
—
0
0
6
54
1.11
0.09
1.0
1.0
—
—
—
0
0
6
58
1.04
0.08
1.5
1.4
—
—
—
0
0
43
449
0.95
0.08
3.4
4.1
6.01
8.07
mmol/l
2.22
37
409
12
108
1.12
0.07
1.8
2.2
0.33
0.70
ug/l
—
7
47
7
85
0.82
0.07
3.0
2.1
—
—
—
0
0
11
99
1.12
0.06
1.0
1.2
—
—
—
0
0
139
1408
0.97
0.06
4.0
3.3
1.25
1.23
mmol/l
0.12
132
1321
13
141
0.92
0.05
3.7
3.6
—
—
—
0
0
30
290
1.04
0.03
4.0
4.1
36.45
16.37
mg/mmol
0.38
19
196
138
1391
0.98
0.03
3.6
3.4
5.56
5.60
mmol/l
0.15
125
1287
82
809
1.02
0.03
5.0
5.0
0.00
0.00
estimate
-0.00
16
161
19
198
0.96
0.02
1.4
1.3
—
—
—
0
0
135
1359
0.98
0.02
4.3
3.8
15.42
14.49
pmol/l
3.61
122
1261
28
284
0.98
0.00
3.6
3.3
124.06
110.76
mg/l
0.07
19
196
81
814
0.99
0.00
3.6
3.6
0.00
0.00
estimate
-0.00
14
153
149
1488
1.00
0.00
4.1
3.7
2.66
2.78
mmol/l
0.85
140
1395
159
1588
1.00
0.00
5.2
4.3
2.22
1.90
mu/l
1.66
144
1485
60
598
1.00
0.00
1.6
1.6
1.93
1.96
g/l
0.04
38
340
54
543
0.99
0.00
2.0
1.9
—
—
—
0
0
41
405
1.02
0.00
2.0
1.8
1.31
1.33
mmol/l
0.08
36
360
10
96
1.04
0.00
3.9
4.5
—
—
—
0
0
42
422
0.99
0.00
3.7
3.7
0.00
0.00
estimate
-0.00
15
160
0
6
0.00
-0.00
0.0
12.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
4.35
—
0
6
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
74
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
34611.11
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
116.00
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
72.80
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_COMPLEX_CARD_DEFEC and mortality.

Females

Parameter HR [95% CI] p-value
Q17_COMPLEX_CARD_DEFEC 6.375 [4.13, 9.84] < 0.001
Birth year 0.996 [0.99, 1.0] 0.339

During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 673 females with Q17_COMPLEX_CARD_DEFEC died.

Males

Parameter HR [95% CI] p-value
Q17_COMPLEX_CARD_DEFEC 6.479 [4.41, 9.53] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 619 males with Q17_COMPLEX_CARD_DEFEC died.

Mortality risk

Mortality risk for people of age

years, who have Q17_COMPLEX_CARD_DEFEC.

N-year risk Females Males
1 0.663% 1.037%
5 3.831% 6.686%
10 9.45% 15.84%
15 17.184% 27.856%
20 28.412% 42.442%

Relationships between endpoints

↥

Index endpoint: Q17_COMPLEX_CARD_DEFEC – Complex cardiac defects

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data