Gestational [pregnancy-induced] oedema and proteinuria without hypertension

O15_GESTAT_OEDEM_PREINUR

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O12
  • Hospital discharge: ICD-9 646[12]A
  • Hospital discharge: ICD-8 6370[02]
  • Cause of death: ICD-10 O12
  • Cause of death: ICD-9 646[12]A
  • Cause of death: ICD-8 6370[02]

2 out of 7 registries used, show all original rules.

3609

4. Check minimum number of events

None

3609

5. Include endpoints

None

3609

6. Filter based on genotype QC (FinnGen only)

3609

Control definitions (FinnGen only)

Control exclude
O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O10-O16
Name in latin
Oedema et proteinuria gravidarum sine hypertensione

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26938 26938 -
Only index persons 25995 25995 -
Unadjusted period prevalence (%)
Whole population 0.77 0.77 -
Only index persons 0.96 0.96 -
Median age at first event (years)
Whole population - 27.57 -
Only index persons - 27.52 -

-FinnGen-

Key figures

All Female Male
Number of individuals 3609 3609 -
Unadjusted period prevalence (%) 1.23 1.23 -
Median age at first event (years) 27.66 27.66 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3285
Matched controls
32850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
63700
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Albuminuria (proteinuria)
+∞
323.0
840
*
63702
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Oedema
+∞
323.0
852
*
O12.0
ICD-10 Finland
Gestational oedema
1479.0
323.0
502
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1464.5
323.0
388
*
O12.1
ICD-10 Finland
Gestational proteinuria
8748.3
323.0
704
*
6462A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Unspecified renal disease in pregnancy, without mention of hypertension
+∞
246.0
233
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
+∞
224.6
213
*
63701
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Hypertonia
+∞
171.4
163
*
6461A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Oedema or excessive weight gain in pregnancy, without mention of hypertension
+∞
149.1
142
*
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
481.2
140.4
139
*
O12.2
ICD-10 Finland
Gestational oedema with proteinuria
+∞
137.5
131
*
63703
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia levis
+∞
131.1
125
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
+∞
85.8
82
*
O14.1
ICD-10 Finland
Severe pre-eclampsia
+∞
70.0
67
*
6424A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, ENNEN SYNNYTYSTÄ]
+∞
65.8
63
*
E66.01
ICD-10 Finland
Obesity due to excess calories
2.9
58.2
399
1512
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
49.7
652
3444
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.5
47.1
419
1835
205
Kela drug reimbursment
Chronic hypertension
2.1
45.3
630
3394
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.7
45.2
1342
9403
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.5
43.7
392
1720
6423A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Transient hypertension of pregnancy[HYPERTENSIO GRAVIDARUM, ENNEN SYNNYTYSTÄ]
+∞
42.8
41
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.2
42.3
461
2226
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
41.5
651
3666
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
41.4
640
3585
Y6099
ICD-8 Finland
Prenatal care and observation
2.7
39.6
296
1173
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
37.0
1435
10639
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
5.8
36.4
106
188
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.7
35.9
898
5877
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
3.3
35.4
187
588
A10BA02
ATC
metformin; oral
1.8
34.7
669
4023
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.2
33.5
356
1689
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.5
32.3
264
1096
C09AA02
ATC
enalapril; systemic
2.0
32.2
462
2491
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
31.4
518
2940
40199
ICD-8 Finland
Essential benign hypertension
8.4
30.9
69
84
C03CA01
ATC
furosemide; systemic
1.8
30.5
597
3591
E66.8
ICD-10 Finland
Other obesity
2.6
30.5
228
901
T90
ICPC
Diabetes non-insulin dependent
1.8
29.9
562
3336
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.8
29.2
203
768
6420X
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Benign essential hypertension complicating pregnancy, childbirth and the puerperium
+∞
29.2
28
*
R80
ICD-10 Finland
Isolated proteinuria
9.8
28.6
58
60
63704
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia gravis
+∞
28.2
27
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.8
28.1
601
3710
C07AG01
ATC
labetalol; systemic
12.7
28.0
50
40
W84
ICPC
Pregnancy high risk
3.1
27.9
160
534
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
27.3
1309
9973
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.6
27.2
205
814
A10AE04
ATC
insulin glargine; parenteral
2.4
26.7
235
1013
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
26.6
359
1881
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.3
26.4
257
1167
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.9
26.2
166
591
A10AE05
ATC
insulin detemir; parenteral
2.9
24.9
159
571
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.9
24.2
151
535
63710
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Eclampsia
+∞
24.0
23
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.7
23.4
554
3507
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.8
23.3
476
2881
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.9
23.2
373
2085
MAA00
NOMESCO Finland
Amniocentesis
3.4
23.1
116
353
63799
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Toxaemia, unspecified
+∞
22.9
22
*
C07AB07
ATC
bisoprolol; oral
1.5
22.0
1132
8639
E66.00
ICD-10 Finland
Metabolic syndrome
2.5
21.4
168
682
N02AX02
ATC
tramadol; systemic, rectal
1.4
20.1
1181
9210
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.5
20.1
964
7218
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.8
19.8
85
229
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.3
19.6
179
788
N02BE01
ATC
paracetamol; systemic, rectal
1.5
18.8
2767
25492
J01DA01
ATC
[U] cefalexin; systemic
1.4
18.5
2000
17320
65700
ICD-8 Finland
Occipital presentation
3.9
18.3
75
194
160
Kela drug reimbursment
exenatide
3.9
18.2
76
200
6424B
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, SYNNYTYKSEN AIKANA]
+∞
17.7
17
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
17.6
458
2956
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
17.4
1400
11470
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
17.1
811
6021
B01AB05
ATC
enoxaparin; parenteral
1.4
17.0
863
6492
A10BJ06
ATC
semaglutide; parenteral
2.9
17.0
104
365
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.6
16.9
457
2977
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.7
16.9
366
2244
O12
ICD-10 Finland
Gestational [pregnancy-induced] oedema and proteinuria without hypertension
+∞
16.7
16
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.5
16.6
129
521
XMA22
NOMESCO Finland
General examination of pregnant woman
2.0
16.4
217
1124
66180
ICD-8 Finland
Occipital presentation
2.7
16.4
111
416
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
9.0
16.4
34
38
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
4.4
16.4
59
136
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.6
16.2
119
467
Z30.2
ICD-10 Finland
Sterilization
1.6
15.8
393
2504
T82
ICPC
Obesity
2.3
15.7
145
643
C08CA01
ATC
amlodipine; oral
1.5
15.7
752
5578
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
15.6
665
4816
C09CA01
ATC
losartan; oral
1.5
15.6
564
3942
SPAT1379
SPAT
Health check-up of pregnant person
1.7
15.5
372
2347
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.1
15.4
86
286
E66.9
ICD-10 Finland
Obesity, unspecified
2.5
15.2
121
498
63499
ICD-8 Finland
Other complications of pregnancy, Other
2.8
15.0
96
347
A10BH01
ATC
sitagliptin; oral
2.0
15.0
200
1043
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.7
14.8
359
2268
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
14.7
448
3005
SPAT1196
SPAT
Monitoring of normal pregnancy
1.8
14.6
259
1490
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.4
14.5
69
204
MAC96
NOMESCO Finland
Other induction or advancement of labour
2.6
14.5
106
416
O16
ICD-10 Finland
Unspecified maternal hypertension
27.3
14.3
19
7
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
2.9
14.2
85
296
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
14.2
1131
9157
SPAT1262
SPAT
Handing over of treatment supplies
1.6
14.2
418
2782
P01AB01
ATC
metronidazole; oral, rectal
1.3
14.2
1364
11379
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
13.8
1661
14302
J01DB01
ATC
cefalexin; oral
1.4
13.7
2579
23780
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
13.6
794
6087
O61.0
ICD-10 Finland
Failed medical induction of labour
4.1
13.6
52
128
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.6
13.5
368
2397
K02.1
ICD-10 Finland
Caries of dentine
1.3
13.5
1767
15386
C09BA02
ATC
enalapril and diuretics; systemic
2.1
13.4
160
797
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
13.3
385
2545
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.3
13.2
117
510
A10BJ02
ATC
liraglutide; parenteral
2.9
13.2
78
271
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
13.1
1816
15912
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
13.0
373
2459
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
13.0
172
890
A10BK03
ATC
empagliflozin; oral
2.0
13.0
164
836
J01AA02
ATC
doxycycline; systemic
1.4
13.0
2474
22716
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.6
12.8
95
377
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
12.6
364
2407
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.9
12.6
187
1016
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
12.6
1735
15152
R51.80
ICD-10 Finland
Headache
1.5
12.6
480
3385
WX110
NOMESCO Finland
Local anesthesy
1.3
12.5
2166
19533
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
12.3
616
4579
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
12.3
1194
9903
G47.3
ICD-10 Finland
Sleep apnoea
1.5
12.3
456
3194
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
12.3
513
3683
C10AA01
ATC
simvastatin; oral
1.4
12.2
877
6944
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.6
12.2
91
362
M79.6
ICD-10 Finland
Pain in limb
1.3
12.2
1074
8784
H02AB06
ATC
prednisolone; systemic
1.3
12.0
1337
11296
C09CA06
ATC
candesartan; oral
1.4
12.0
581
4288
M54.5
ICD-10 Finland
Low back pain
1.3
12.0
997
8074
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.8
11.9
225
1324
SPAT1263
SPAT
Sampling
1.3
11.9
1260
10575
O30.0
ICD-10 Finland
Twin pregnancy
2.8
11.9
74
266
O82.0
ICD-10 Finland
Delivery by elective caesarean section
1.9
11.8
163
860
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
11.8
860
6818
A10BX07
ATC
[U] liraglutide; parenteral
3.9
11.8
48
126
A12BA01
ATC
potassium chloride; oral
2.6
11.8
83
322
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.5
11.8
93
384
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
3.3
11.7
58
179
W78
ICPC
Pregnancy
1.5
11.7
468
3330
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
11.6
1185
9878
C03AA03
ATC
hydrochlorothiazide; oral
1.7
11.5
223
1323
6425B
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Severe pre-eclampsia[PRAE-ECLAMPSIA GRAVIS, SYNNYTYKSEN AIKANA]
+∞
11.5
11
*
O11
ICD-10 Finland
Pre-eclampsia superimposed on chronic hypertension
+∞
11.5
11
*
6425A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Severe pre-eclampsia[PRAE-ECLAMPSIA GRAVIS, ENNEN SYNNYTYSTÄ]
+∞
11.5
11
*
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
11.5
766
5988
J01FF01
ATC
clindamycin; systemic
1.4
11.4
752
5861
A08AB01
ATC
orlistat; oral
4.9
11.4
36
74
C10AA05
ATC
atorvastatin; oral
1.4
11.3
787
6186
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
11.3
75
279
C07AB02
ATC
metoprolol; systemic
1.5
11.3
436
3078
H04AA01
ATC
glucagon; nasal, parenteral
2.9
11.3
68
241
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.0
11.2
62
207
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.7
11.2
78
298
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
11.2
2248
20500
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
11.2
2058
18544
QBJ30
NOMESCO Finland
Correction of abdominal apron
3.9
11.1
44
113
SPAT1197
SPAT
Extensive health check-up of expecting family
1.5
11.1
416
2916
ACC51
NOMESCO Finland
Release of median nerve
1.7
11.1
231
1399
N03AX12
ATC
gabapentin; oral
1.5
11.0
432
3057
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
3.0
11.0
63
214
WX290
NOMESCO Finland
Other blockade of nerve
1.3
10.7
1356
11602
A10BB12
ATC
glimepiride; oral
2.2
10.7
111
523
162
Kela drug reimbursment
liraglutide
3.7
10.7
45
122
8221
FHL
Sterilization of the laparotomy pathway
2.0
10.7
140
726
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
10.7
1499
12999
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
5.4
10.7
31
58
O20.0
ICD-10 Finland
Threatened abortion
2.2
10.7
103
470
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.9
10.7
64
226
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.1
10.6
119
579
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
10.5
495
3634
C09DA01
ATC
losartan and diuretics; oral
1.7
10.4
233
1438
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.2
10.4
101
462
63709
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia NUD
+∞
10.4
10
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
10.3
539
4034
SGA01
NOMESCO Finland
Tooth opening as first aid
1.4
10.2
460
3346
C10AA07
ATC
rosuvastatin; oral
1.4
10.2
564
4263
L03
ICPC
Low back symptom/complaint
1.3
10.1
714
5610
T89
ICPC
Diabetes insulin dependent
2.3
10.1
93
413
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
10.1
147
792
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
9.9
489
3615
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.5
9.9
341
2343
SPAT1324
SPAT
Screening procedure
1.3
9.8
768
6127
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
9.8
808
6496
R03AC02
ATC
salbutamol; inhalant
1.3
9.8
1645
14528
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
9.8
487
3606
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
5.0
9.7
30
61
S18
ICPC
Laceration/cut
1.3
9.6
1080
9060
C08CA13
ATC
lercanidipine; oral
1.6
9.6
270
1773
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
9.5
1047
8758
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
3.6
9.5
41
115
SPAT1097
SPAT
Recording of ECG
1.5
9.5
351
2451
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
2.7
9.4
62
233
65710
ICD-8 Finland
Occipital presentation
2.3
9.4
87
391
A46
ICD-10 Finland
Erysipelas
1.6
9.4
265
1741
O10.9
ICD-10 Finland
Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
+∞
9.4
9
*
O99.80
ICD-10 Finland
The fear of childbirth
1.8
9.3
165
953
A10BD07
ATC
metformin and sitagliptin; systemic
2.3
9.3
85
378
EBA00
NOMESCO Finland
Extraction of tooth
1.3
9.3
879
7200
WZA90
NOMESCO Finland
Other doctors statement
1.3
9.3
633
4944
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
2.0
9.3
120
620
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
9.2
284
1906
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.5
9.2
71
292
O60
ICD-10 Finland
Preterm labour and delivery
2.2
9.2
95
448
8811
FHL
Cesarean section
1.6
9.1
213
1336
78900
ICD-8 Finland
Abnormal urinary constituents of unspecified cause, Albuminuria
11.5
9.1
16
14
L86
ICPC
Back syndrome with radiating pain
1.8
9.0
159
918
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
1.8
9.0
162
942
O40
ICD-10 Finland
Polyhydramnios
3.0
9.0
48
159
A10BH05
ATC
linagliptin; oral
2.3
8.9
78
342
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
8.9
286
1940
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.6
8.9
221
1408
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
8.9
1125
9563
O41.0
ICD-10 Finland
Oligohydramnios
2.4
8.8
71
299
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.4
8.8
70
290
J01CA04
ATC
amoxicillin; systemic
1.3
8.8
2571
24137
66120
ICD-8 Finland
Occipital presentation
9.5
8.8
17
18
C02AC05
ATC
moxonidine; oral
2.2
8.7
85
393
A10BX04
ATC
[U] exenatide; parenteral
4.0
8.7
33
83
R75
ICPC
Sinusitis acute/chronic
1.7
8.7
163
958
K04.0
ICD-10 Finland
Pulpitis
1.5
8.7
276
1866
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.3
8.6
42
130
C08CA05
ATC
nifedipine; systemic
1.9
8.6
131
718
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
6.1
8.6
22
36
A10BK01
ATC
dapagliflozin; oral
2.1
8.6
93
449
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
3.2
8.5
43
137
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.4
8.5
71
304
C07AG02
ATC
carvedilol; oral
2.0
8.5
106
545
R02
ICPC
Shortness of breath/dyspnoea
1.5
8.4
299
2070
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.6
8.4
205
1298
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
8.4
2121
19484
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.4
610
4801
SPAT1301
SPAT
No procedures
1.3
8.3
827
6806
K86
ICPC
Hypertension uncomplicated
1.5
8.3
248
1654
R05
ICPC
Cough
1.3
8.2
669
5353
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
8.2
1395
12239
A10AE06
ATC
insulin degludec; parenteral
2.3
8.2
72
316
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.5
8.1
36
104
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.6
8.1
57
224
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
8.1
337
2412
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.1
868
7210
A10BJ01
ATC
exenatide; parenteral
4.2
8.1
29
70
R09
ICPC
Sinus symptom/complaint
1.5
8.1
273
1871
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
4.0
8.0
30
75
L08
ICPC
Shoulder symptom/complaint
1.4
8.0
501
3850
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
2.4
8.0
62
256
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.9
8.0
46
159
25009
ICD-8 Finland
Diabetes mellitus, Unspecified
5.3
8.0
23
44
C10AX09
ATC
ezetimibe; oral
1.6
8.0
210
1360
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.7
7.8
170
1043
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
7.7
581
4592
-1
NOMESCO Finland
NA
1.3
7.7
967
8178
C02EA02
ATC
NA
2.5
7.7
60
247
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.7
893
7484
A10AA02
ATC
NA
2.2
7.5
69
312
N03AX16
ATC
pregabalin; oral
1.3
7.5
640
5149
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
7.5
365
2691
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
7.5
776
6408
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.5
7.5
227
1518
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
7.5
49
186
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.4
7.4
58
240
H01
ICPC
Ear pain/earache
1.4
7.4
307
2195
C07AB03
ATC
atenolol; systemic
1.9
7.4
109
594
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
7.4
397
2977
B01AC04
ATC
clopidogrel; oral
1.5
7.3
215
1429
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.7
7.3
47
176
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
7.3
282
1991
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
7.3
1108
9570
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.1
7.3
81
398
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.4
7.2
395
2970
SPAT1380
SPAT
Postpartum check-up
1.5
7.2
284
2010
M04AA01
ATC
allopurinol; systemic
1.7
7.2
157
966
KMAK
NOMESCO Finland
NA
1.2
7.2
1631
14683
65300
ICD-8 Finland
Occipital presentation
2.7
7.2
46
170
A03
ICPC
Fever
1.4
7.1
442
3390
66110
ICD-8 Finland
Occipital presentation
3.7
7.1
29
79
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
7.1
223
1505
A10AA01
ATC
NA
2.2
7.0
63
283
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
7.0
302
2176
SGA03
NOMESCO Finland
Demanding opening and dilatation of root canal of tooth
1.5
7.0
259
1810
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.5
7.0
226
1536
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
7.0
42
152
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
2.8
7.0
41
146
J45.1
ICD-10 Finland
Nonallergic asthma
1.6
6.8
179
1158
O21.1
ICD-10 Finland
Hyperemesis gravidarum with metabolic disturbance
4.8
6.8
21
44
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
6.8
276
1965
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
6.8
623
5059
C07BB07
ATC
bisoprolol and thiazides; systemic
1.9
6.8
96
517
C09DA06
ATC
candesartan and diuretics; oral
1.6
6.8
151
937
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.4
6.7
283
2031
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.7
641
5234
EBA10
NOMESCO Finland
Surgical removal of tooth
1.4
6.7
308
2248
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.4
6.6
286
2062
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.3
6.6
56
242
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
6.6
1023
8827
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.0
6.6
76
379
C01DA14
ATC
isosorbide mononitrate; oral
1.6
6.6
159
1007
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.6
6.6
167
1075
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.4
6.6
281
2023
O02.1
ICD-10 Finland
Missed abortion
1.6
6.6
176
1147
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
1.7
6.5
119
699
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.6
6.5
165
1058
WX307
NOMESCO Finland
Obstetric epidural analgesia
1.5
6.5
246
1726
AN1
HP
Coronary angiography
1.6
6.5
152
954
E66
ICD-10 Finland
Obesity
1.7
6.5
122
724
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
6.5
475
3738
SPAT1283
SPAT
Restricted health certificate
1.3
6.5
552
4433
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.4
416
3212
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.2
6.4
59
269
XF600
NOMESCO Finland
Bloodpressure measurement
1.7
6.4
130
788
D73
ICPC
Gastroenteritis presumed infection
2.0
6.4
77
392
SPAT1260
SPAT
Consultation of another employee
1.3
6.4
455
3566
MAC00
NOMESCO Finland
Rupture of amniotic membrane
4.7
6.4
20
43
27799
ICD-8 Finland
Obesity not specified as of endocrine origin
4.1
6.4
23
57
H3600, E103
ICD-10 Finland
NA
3.2
6.4
30
93
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.9
6.4
93
509
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
6.3
298
2184
L17
ICPC
Foot/toe symptom/complaint
1.3
6.3
661
5452
O23.1
ICD-10 Finland
Infections of bladder in pregnancy
4.6
6.3
20
44
6426A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Eclampsia[ECLAMPSIA , ENNEN SYNNYTYSTÄ]
+∞
6.2
6
*
A10BD03
ATC
metformin and rosiglitazone; systemic
3.1
6.2
31
100
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
6.2
441
3449
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.5
6.2
228
1593
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.2
1516
13671
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.5
6.2
178
1179
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
2.8
6.2
36
128
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.6
6.2
167
1091
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.1
722
6037
R96
ICPC
Asthma
1.4
6.1
238
1680
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.6
6.1
135
836
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.1
952
8208
R06.5
ICD-10 Finland
Mouth breathing
1.5
6.1
177
1173
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.3
6.1
384
2954
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
3.2
6.1
29
91
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
3.6
6.1
25
70
4019X
ICD-9 Finland
Essential hypertension, Unspecified
3.0
6.1
32
108
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
6.7
6.0
14
21
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
2.2
6.0
56
258
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.4
6.0
280
2046
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
6.0
253
1817

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1224
7609
1.92
69.00
5.1
3.8
21.1
7.0
mg/mmol
8.96
847
4334
1169
7251
1.91
65.67
4.2
3.1
453.7
478.4
mg/l
0.06
808
4035
1236
8062
1.81
57.50
4.3
3.1
6.8
6.8
mmol/l
0.09
1105
6753
1014
6908
1.65
36.86
2.7
2.2
3257.4
3466.0
umol/l
0.06
887
5966
933
6510
1.58
29.60
5.0
4.0
1.0
1.0
kg/l
1.19
173
1002
1892
15372
1.49
29.09
4.4
3.6
0.0
0.0
estimate
0.13
369
2855
2007
16631
1.47
27.03
4.7
3.9
6.7
6.4
mmol/l
7.42
1855
15283
1894
15530
1.46
26.88
5.7
4.8
0.0
0.0
estimate
0.80
377
2893
1105
8148
1.51
26.81
4.9
3.9
0.0
0.0
estimate
0.81
362
2892
1897
15666
1.44
25.25
4.5
3.6
0.0
0.0
estimate
0.23
359
2896
2456
21723
1.41
19.49
5.2
4.3
—
—
—
0
0
3346
31575
1.82
19.32
15.1
12.6
139.7
139.7
mmol/l
0.22
3302
30733
3351
31672
1.81
18.73
15.3
12.7
3.9
3.9
mmol/l
7.22
3304
30745
116
473
2.50
18.44
2.6
2.4
206.5
48.8
ug/min
1.20
70
281
928
7050
1.43
17.90
1.9
1.7
1.0
0.9
mg/l
0.17
743
5286
1180
9362
1.39
17.64
2.5
2.4
52.7
57.5
u/l
2.51
1121
8574
2364
21035
1.36
16.30
5.1
4.3
595.3
1710.1
e6/l
1.65
34
243
847
6438
1.41
16.02
2.6
2.6
948.5
798.1
ng/l
0.42
713
5393
2998
27824
1.46
15.59
6.6
5.0
40.3
38.4
mmol/mol
22.82
2855
25822
1216
9886
1.35
14.98
3.2
3.0
32.0
94.4
ng/l
0.56
689
5589
2594
23538
1.36
14.97
7.1
7.2
76.4
75.6
u/l
0.35
2472
22122
925
7233
1.37
14.56
4.5
3.6
—
—
—
0
0
3304
31381
1.63
14.55
13.7
11.9
19.8
19.8
mg/l
0.00
2705
24232
1785
15449
1.31
13.77
5.0
5.8
9.6
9.8
umol/l
0.41
1699
14578
1458
12285
1.31
13.66
5.1
4.3
35.5
36.2
g/l
5.08
1384
11376
35
83
4.25
13.61
1.5
1.4
—
—
—
0
0
756
5807
1.38
13.08
3.1
2.4
6.8
8.1
e6/l
2.03
666
5043
1187
9799
1.31
12.63
3.3
2.8
—
—
—
0
0
1228
10188
1.31
12.59
6.8
6.3
1.1
1.1
inr
0.17
378
3117
2302
20762
1.30
12.37
3.7
3.3
—
—
—
0
0
54
183
2.98
12.35
3.2
1.6
0.9
1.2
g/24h
—
6
11
1234
10284
1.30
12.13
4.1
3.4
90.5
86.8
e6/l
0.06
879
6782
273
1738
1.62
12.03
2.3
2.1
5.1
5.9
ug/l
0.39
247
1498
288
1868
1.59
11.74
2.1
2.1
8834.8
4826.1
u/l
0.77
114
759
1037
8475
1.31
11.67
3.8
3.2
—
—
—
0
0
293
1913
1.58
11.62
4.9
3.4
5.8
5.8
kpa
0.02
285
1859
1012
8248
1.32
11.61
3.7
2.9
28.8
78.5
e6/l
1.96
786
6146
160
897
1.82
11.21
2.3
1.8
1.4
1.6
g/l
2.37
142
769
2572
23679
1.30
11.06
4.3
4.1
12.7
11.5
mm/h
4.98
2444
22013
1068
8822
1.30
10.97
4.6
3.6
7.4
7.4
ph
0.80
185
1693
68
282
2.44
10.57
1.6
1.4
13.0
11.8
mmol/l
—
8
43
286
1901
1.55
10.48
5.7
3.4
1.6
2.0
mmol/l
1.07
244
1571
791
6304
1.33
10.47
3.9
3.9
—
—
—
0
0
1661
14561
1.26
10.38
7.3
5.7
1.2
1.2
mmol/l
0.04
1429
12201
935
7649
1.30
10.20
3.4
2.8
0.3
0.3
e6/l
0.11
717
5607
118
621
1.93
10.09
4.2
4.0
3.8
3.8
mmol/l
1.22
109
587
110
566
1.97
10.05
2.3
2.1
4.7
5.4
umol/l
0.58
76
415
923
7556
1.30
9.98
3.3
2.7
—
—
—
0
0
153
888
1.75
9.59
3.3
2.8
0.5
0.3
g/l
1.49
77
303
389
2814
1.43
9.35
7.2
6.2
104.2
104.6
mmol/l
0.93
375
2761
396
2881
1.42
9.22
20.0
17.2
1.2
1.2
inr
0.21
69
456
198
1250
1.62
9.07
3.5
2.4
0.3
0.3
e6/l
0.03
191
1203
444
3306
1.39
9.04
1.8
1.6
—
—
—
0
0
771
6245
1.30
8.90
1.3
1.3
10.3
11.9
u/ml
0.31
304
2526
208
1335
1.59
8.90
6.5
7.0
24.5
24.6
mmol/l
0.18
196
1232
2849
26838
1.29
8.75
5.0
4.5
14.7
14.6
pmol/l
0.91
2704
24748
273
1872
1.50
8.66
10.3
6.7
9.4
8.1
mmol/l
2.66
268
1798
316
2231
1.46
8.66
3.9
3.4
—
—
—
0
0
29
84
3.47
8.63
36.2
31.4
7.0
7.5
ug/l
0.53
29
77
431
3223
1.38
8.54
7.8
4.6
1.1
1.0
mmol/l
2.22
412
2980
161
981
1.67
8.49
4.0
2.9
25.3
25.4
mmol/l
0.13
155
952
309
2183
1.45
8.44
6.8
7.2
96.6
96.2
%
1.33
299
2101
622
4926
1.32
8.43
3.1
3.2
166.2
276.2
ng/l
0.85
411
3235
232
1549
1.53
8.36
3.9
2.8
4.8
4.7
kpa
0.30
225
1498
292
2060
1.45
8.04
7.1
7.5
119.1
119.9
g/l
0.31
281
1983
794
6534
1.28
8.00
1.3
1.3
22.7
29.2
iu/ml
1.34
271
2096
1671
14931
1.22
7.94
4.1
3.8
—
—
—
0
0
153
938
1.66
7.91
4.2
2.5
0.7
0.7
%
0.14
148
897
578
4573
1.31
7.86
2.7
2.4
1.2
1.3
e6/l
0.14
342
2461
347
2542
1.40
7.76
6.5
6.7
1.0
1.1
mmol/l
0.05
270
1981
1184
10257
1.23
7.49
3.2
3.1
29.6
30.7
u/l
0.40
1119
9734
55
244
2.27
7.46
3.7
2.9
182.0
22.7
mg/l
1.84
41
164
649
5249
1.29
7.45
3.1
2.6
522.0
508.9
mosm/kgh2o
0.82
558
4447
346
2551
1.39
7.45
6.6
6.6
5.0
5.1
kpa
0.49
329
2433
345
2549
1.39
7.34
6.6
6.6
12.6
13.2
kpa
1.22
326
2429
522
4110
1.32
7.32
1.8
1.9
—
—
—
0
0
111
637
1.77
7.32
3.6
2.9
1.5
1.4
mg/l
0.84
103
596
207
1393
1.52
7.22
3.9
5.1
—
—
—
0
0
13
23
5.67
7.06
14.0
13.6
4.8
5.4
mmol/l
0.29
13
23
45
190
2.39
6.85
1.6
1.4
1.6
1.4
nmol/l
0.50
40
172
151
959
1.60
6.82
4.3
2.6
1.4
1.2
%
0.60
151
947
200
1360
1.50
6.66
8.3
7.9
94.5
94.4
%
0.26
200
1354
529
4231
1.29
6.58
3.2
2.2
12.8
13.6
umol/l
1.78
500
3910
3150
30317
1.31
6.55
5.8
5.3
1.8
2.0
mu/l
1.82
2999
28178
477
3775
1.30
6.42
2.1
2.0
29.1
29.2
s
0.31
462
3657
253
1815
1.42
6.39
2.1
2.7
158.2
135.0
ng/l
0.33
223
1641
737
6156
1.25
6.39
1.7
1.6
432.2
39098628.7
pmol/l
5.53
652
5123
45
197
2.30
6.35
1.8
2.0
2.2
2.4
u/field
0.04
24
84
2834
26964
1.24
6.30
18.4
15.2
331.1
331.1
g/l
0.03
2812
26797
1469
13159
1.20
6.28
6.3
5.0
1.2
1.2
mmol/l
0.30
1364
11877
3409
33248
1.46
6.22
11.0
9.9
25.1
23.8
u/l
2.59
3346
32086
1965
18084
1.19
6.14
7.9
9.1
4.1
3.9
e9/l
3.72
1743
15874
249
1795
1.42
6.13
9.5
7.3
—
—
—
0
0
88
502
1.77
5.99
2.8
2.1
0.9
0.8
nmol/l
0.91
76
425
1327
11833
1.19
5.86
1.9
1.9
95.2
100.2
pmol/l
3.42
682
5705
280
2080
1.38
5.79
3.3
2.9
—
—
—
0
0
131
842
1.58
5.69
5.9
4.2
—
—
—
0
0
96
572
1.70
5.63
1.6
1.3
—
—
—
0
0
1751
16026
1.18
5.63
5.5
5.8
2.0
2.0
e9/l
0.53
1572
14236
89
520
1.73
5.60
1.5
1.3
105.3
112.2
u/ml
0.29
23
121
441
3520
1.29
5.55
3.5
2.3
21.3
22.6
%
1.39
391
3008
966
8405
1.20
5.52
2.1
2.0
155.6
149.2
u/l
0.11
921
7876
513
4186
1.26
5.40
3.0
2.6
5.3
4.6
e6/l
0.48
283
2093
474
3842
1.27
5.27
3.4
2.2
2.4
2.4
g/l
0.05
443
3540
262
1956
1.37
5.27
7.6
5.9
1.2
1.2
mmol/l
0.25
257
1890
92
555
1.67
5.18
1.3
1.2
249.6
267.5
u/ml
0.27
58
356
1701
15615
1.17
5.06
5.4
5.9
0.0
0.0
e9/l
0.41
1499
13560
33
141
2.35
4.98
1.6
1.8
3.8
2.6
u/field
0.42
25
94
592
4956
1.23
4.94
1.4
1.4
602.5
582.5
titre
0.07
110
1092
100
627
1.61
4.87
4.3
2.2
—
—
—
0
0
469
3833
1.26
4.86
2.0
1.8
—
—
—
0
0
3116
30148
1.25
4.84
4.9
4.2
6.0
5.7
mmol/l
23.17
2940
27743
153
1057
1.47
4.80
1.7
1.9
0.2
0.2
g/l
0.52
147
994
831
7227
1.19
4.67
2.5
2.2
3.0
2.8
mg/l
0.91
755
6153
3369
32938
1.34
4.65
13.5
11.1
—
—
—
0
0
1688
15552
1.16
4.64
5.5
5.8
0.5
0.5
e9/l
0.25
1490
13530
75
443
1.71
4.61
1.1
1.3
—
—
—
0
0
193
1407
1.39
4.53
3.2
3.2
—
—
—
0
0
1749
16180
1.16
4.50
5.5
6.0
0.2
0.2
e9/l
1.64
1577
14302
19
66
2.89
4.33
1.1
1.0
—
—
—
0
0
19
66
2.89
4.33
1.2
1.2
—
—
—
0
0
70
415
1.70
4.27
1.4
1.5
—
—
—
0
0
1507
13827
1.15
4.26
8.9
8.7
0.0
0.0
e9/l
3.20
1260
11297
158
1126
1.42
4.24
1.9
1.6
16.2
8.1
u/ml
—
5
27
25
102
2.46
4.21
3.9
1.9
8.7
9.5
mmol/l
0.68
20
77
17
57
2.99
4.12
4.8
4.7
—
—
—
0
0
92
596
1.56
3.97
3.3
4.0
—
—
—
0
0
28
124
2.27
3.96
2.3
2.1
529.7
499.5
min
1.06
19
96
141
998
1.43
3.95
8.0
3.8
24.2
24.4
mmol/l
0.32
122
911
514
4352
1.21
3.82
3.0
3.2
0.8
0.8
mmol/l
0.11
486
4042
135
957
1.43
3.77
1.2
1.2
—
—
—
0
0
183
1367
1.36
3.75
3.5
3.1
5.2
5.2
kpa
0.12
168
1280
675
5870
1.18
3.74
1.9
1.6
—
—
—
0
0
209
1596
1.33
3.70
1.5
1.4
—
—
—
0
0
373
3069
1.24
3.66
1.9
2.2
356.1
374.8
nmol/l
1.31
353
2823
150
1090
1.39
3.65
1.7
1.9
1.2
1.2
g/l
0.33
144
1026
23
97
2.38
3.64
1.0
1.1
—
—
—
0
0
180
1350
1.35
3.61
3.5
3.1
7.4
7.4
ph
1.27
22
178
2765
26659
1.16
3.45
16.6
14.6
13.7
13.6
%
2.06
2717
26123
33
166
2.00
3.43
2.5
2.2
642.9
610.9
ml
0.20
24
119
78
505
1.56
3.42
4.0
2.8
23.7
25.0
mmol/l
1.90
67
445
68
428
1.60
3.37
1.1
1.1
80.0
22766.3
iu/ml
0.55
21
106
37
196
1.90
3.33
1.8
1.4
1879.5
2020.5
ml
0.23
11
35
16
60
2.67
3.22
1.1
1.2
—
—
—
0
0
39
214
1.83
3.17
2.0
1.5
6.8
6.2
mmol/l
0.51
29
145
147
1093
1.36
3.15
2.0
1.9
21.6
20.9
s
0.40
130
916
1518
14134
1.13
3.14
5.6
6.0
0.7
0.7
%
0.87
1426
13143
58
358
1.63
3.13
2.2
2.6
—
—
—
0
0
473
4055
1.19
3.08
1.7
1.6
—
—
—
0
0
3162
30880
1.19
3.07
4.8
4.1
4.8
4.9
mmol/l
11.61
3029
28795
84
1218
0.68
3.04
1.3
1.3
—
—
—
0
0
106
751
1.42
3.04
1.2
1.4
22.2
28.8
u/l
1.41
92
622
64
409
1.57
3.01
1.3
1.6
48.7
56.5
mu/l
0.25
57
367
69
449
1.55
3.00
4.7
2.8
—
—
—
0
0
157
1190
1.33
2.99
8.8
9.0
—
—
—
0
0
125
916
1.38
2.96
3.8
5.4
0.9
0.9
%
0.46
116
856
54
333
1.63
2.95
1.1
1.3
—
—
—
0
0
1621
15193
1.12
2.94
3.4
2.8
86.1
86.0
ug/l
0.01
1531
14186
1570
14691
1.12
2.92
5.8
6.2
7.9
8.2
%
2.79
1484
13760
23
109
2.12
2.84
2.1
2.7
—
—
—
0
0
71
472
1.51
2.83
1.3
1.6
—
—
—
0
0
3140
30702
1.17
2.71
4.6
4.1
1.5
1.6
mmol/l
34.35
2981
28511
124
922
1.36
2.71
3.8
5.3
1.6
1.6
%
0.26
113
857
1611
15142
1.12
2.70
5.6
6.0
29.5
29.4
%
0.23
1515
14110
102
735
1.40
2.70
3.7
6.6
1.4
1.2
mmol/l
0.62
85
651
1592
14963
1.11
2.66
5.5
5.8
56.8
56.4
%
0.79
1505
13983
1556
14613
1.11
2.63
5.6
6.0
2.8
2.8
%
0.02
1461
13580
25
127
1.98
2.60
1.2
2.2
—
—
—
0
0
188
1495
1.27
2.55
2.1
1.9
—
—
—
0
0
39
230
1.70
2.55
2.1
2.0
—
—
—
0
0
10
33
3.04
2.52
1.5
1.2
—
—
—
0
0
802
7264
1.13
2.51
4.1
4.3
—
—
—
0
0
3025
29536
1.15
2.47
4.2
3.7
1.3
1.2
mmol/l
17.04
2864
27223
84
1167
0.71
2.46
1.5
1.5
—
—
—
0
0
128
974
1.33
2.43
3.0
3.2
—
—
—
0
0
74
514
1.45
2.42
3.9
2.9
—
—
—
0
0
536
4744
1.15
2.36
1.8
1.7
1212.9
1182.7
nmol/l
0.30
461
3550
1065
9845
1.12
2.35
2.2
2.1
—
—
—
0
0
54
354
1.53
2.35
3.4
2.5
—
—
—
0
0
3193
31325
1.17
2.32
5.3
4.5
2.8
2.9
mmol/l
4.25
3028
29029
82
1131
0.72
2.31
1.4
1.4
—
—
—
0
0
1511
14254
1.10
2.24
2.5
2.3
76.0
78.3
nmol/l
2.66
1415
12978
130
1005
1.30
2.23
1.3
1.3
—
—
—
0
0
3527
34967
1.38
2.23
21.2
18.0
263.7
266.7
e9/l
2.15
3479
34169
3528
34982
1.38
2.19
21.1
17.9
90.5
90.8
fl
4.34
3508
34555
3528
34983
1.38
2.18
21.1
17.9
30.0
30.1
pg
3.38
3508
34554
83
1126
0.73
2.14
1.4
1.4
—
—
—
0
0
3528
34988
1.37
2.13
21.2
17.9
4.5
4.4
e12/l
3.31
3469
34106
3528
34989
1.37
2.11
21.3
18.0
6.8
6.6
e9/l
8.37
3469
34100
439
3864
1.15
2.10
1.7
1.5
—
—
—
0
0
173
2120
0.81
2.05
1.5
1.4
—
—
—
0
0
6
15
4.00
2.04
1.2
1.3
—
—
—
0
0
49
326
1.51
2.03
2.8
3.2
0.8
0.8
nmol/l
0.04
40
256
3528
34998
1.36
2.02
21.3
18.0
132.9
132.6
g/l
0.68
3508
34566
242
2036
1.20
2.01
2.0
2.5
66.2
67.0
g/l
0.79
225
1864
868
7999
1.11
2.00
6.3
6.8
—
—
—
0
0
36
224
1.61
1.99
2.8
2.2
—
—
—
0
0
267
2272
1.19
1.96
1.4
1.4
—
—
—
0
0
75
546
1.38
1.95
2.4
2.1
126.3
128.4
g/l
0.34
55
386
18
91
1.98
1.95
1.7
1.3
—
—
—
0
0
62
437
1.43
1.94
3.4
2.5
8.6
8.3
kpa
0.73
56
404
901
8335
1.11
1.92
1.7
1.6
1.4
1.3
mmol/l
2.73
763
7025
61
432
1.42
1.87
1.3
1.5
—
—
—
0
0
22
122
1.81
1.84
1.8
2.8
—
18.6
—
0
9
147
1188
1.25
1.83
8.7
7.8
24.2
24.3
mmol/l
0.24
135
1121
51
728
0.70
1.82
1.1
1.5
0.3
0.5
nmol/l
3.13
40
569
29
175
1.66
1.82
3.1
2.1
12.4
10.9
%
1.28
29
175
67
486
1.39
1.81
1.1
1.1
—
—
—
0
0
198
2354
0.83
1.77
1.6
1.7
—
—
—
0
0
304
2642
1.16
1.76
3.2
3.2
4.5
4.5
pmol/l
0.30
283
2366
878
8149
1.10
1.75
1.3
1.3
1.3
1.6
u/ml
0.49
260
2232
339
2973
1.15
1.74
1.2
1.2
132.6
152.8
iu/ml
0.48
139
1142
500
4508
1.13
1.70
2.1
2.2
123.4
105.0
ug/g
0.66
391
3486
8
177
0.45
1.69
11.0
11.3
947.0
907.8
nmol/l
—
8
169
86
658
1.31
1.67
1.4
1.7
9539.9
9418.7
e6/l
0.01
68
475
116
924
1.26
1.66
1.2
1.4
318.0
291.2
ug/g
0.79
70
497
314
2750
1.16
1.65
4.4
3.7
—
—
—
0
0
73
547
1.34
1.64
1.7
1.6
—
—
—
0
0
5
131
0.38
1.62
1.6
1.5
—
—
—
0
0
85
655
1.30
1.58
3.7
3.0
7.4
7.4
ph
0.30
65
544
54
388
1.40
1.57
1.3
1.4
258.0
374.3
pmol/l
0.85
46
303
125
1015
1.24
1.53
1.3
1.3
10.9
5.5
u/ml
0.29
18
110
263
2289
1.16
1.52
5.6
3.0
102.6
74.5
ng/l
4.50
241
1959
50
690
0.72
1.52
1.2
1.4
12.6
3.7
ug/l
0.50
41
619
126
1030
1.23
1.47
1.3
1.3
6.3
9.4
u/ml
0.35
22
179
6
22
2.73
1.43
1.0
1.4
115.6
162.2
mmol/l
—
6
22
380
3409
1.13
1.43
2.2
2.5
5.6
6.2
umol/l
0.44
323
2883
797
7437
1.09
1.41
3.6
3.4
98.2
97.0
%
0.74
770
7208
9
40
2.25
1.40
1.3
1.3
—
—
—
0
0
226
1960
1.16
1.39
1.3
1.2
—
—
—
0
0
39
271
1.44
1.39
2.3
2.7
—
—
—
0
0
33
222
1.49
1.38
1.1
1.2
406.7
151.0
titre
—
9
49
264
2320
1.15
1.37
3.9
4.1
0.0
0.4
%
0.96
63
501
5
17
2.94
1.36
1.0
1.1
—
—
—
0
0
25
160
1.57
1.31
1.4
1.2
—
—
—
0
0
45
326
1.39
1.30
1.5
1.5
—
—
—
0
0
204
1767
1.16
1.30
1.5
1.8
1.3
1.4
g/l
0.05
189
1616
14
76
1.85
1.29
1.1
1.6
—
—
—
0
0
8
34
2.36
1.29
45.1
7.1
—
—
—
0
0
1088
10320
1.08
1.29
5.4
5.9
—
—
—
0
0
47
345
1.37
1.26
1.1
1.4
—
—
—
0
0
17
100
1.70
1.23
2.1
1.9
—
—
—
0
0
95
771
1.24
1.23
2.4
2.1
—
—
—
0
0
63
487
1.30
1.21
1.0
1.1
—
—
—
0
0
32
221
1.45
1.21
1.5
1.9
—
—
—
0
0
97
791
1.23
1.20
1.9
2.0
2.6
2.1
ug/l
0.20
86
709
45
331
1.36
1.20
1.4
1.3
1.1
1.4
nmol/l
0.84
38
262
27
181
1.50
1.18
1.4
1.2
—
—
—
0
0
78
623
1.26
1.17
1.9
2.3
—
—
—
0
0
262
2331
1.13
1.16
2.2
2.6
4.1
4.1
e9/l
0.20
219
1895
15
248
0.60
1.15
1.3
1.1
—
—
—
0
0
5
20
2.50
1.15
1.0
2.1
0.3
0.1
%
—
5
13
40
292
1.37
1.13
2.7
3.1
—
—
—
0
0
88
716
1.23
1.13
1.6
1.6
29.3
22.9
iu/ml
—
5
20
12
65
1.85
1.13
1.0
1.0
79.0
75.4
ug/l
0.11
12
56
285
2555
1.13
1.13
3.7
4.1
0.9
0.9
%
0.12
75
634
176
1528
1.16
1.12
1.2
1.3
0.5
1.5
u/ml
1.44
19
127
46
345
1.34
1.11
1.1
1.4
0.4
0.4
g/l
0.27
37
235
46
345
1.34
1.11
1.1
1.4
3.6
2.8
g/l
1.39
37
234
46
346
1.33
1.09
1.1
1.4
6.9
6.8
g/l
0.08
37
234
674
6319
1.08
1.08
1.5
1.5
21.4
21.6
nmol/l
0.16
608
5382
58
453
1.28
1.06
1.2
1.7
—
—
—
0
0
290
2615
1.12
1.05
2.1
2.2
0.2
0.2
g/l
0.41
276
2464
261
2904
0.89
1.04
1.3
1.4
—
—
—
0
0
160
1390
1.16
1.03
1.1
1.1
—
—
—
0
0
47
359
1.31
1.02
2.4
2.3
—
—
—
0
0
278
2508
1.12
1.01
2.9
2.5
1.9
1.8
%
1.03
254
2223
5
108
0.46
1.00
2.0
2.3
199.8
161.1
nmol/l
—
5
92
131
1123
1.17
1.00
1.3
1.3
11.6
36.3
u/ml
—
9
80
22
147
1.50
1.00
1.1
1.1
—
—
—
0
0
19
286
0.66
1.00
1.1
1.2
—
—
—
0
0
270
2990
0.90
1.00
3.8
3.7
—
—
—
0
0
7
35
2.00
1.00
1.0
1.1
—
—
—
0
0
66
529
1.25
1.00
1.3
1.2
2.8
4.3
u/ml
0.87
28
206
63
503
1.26
0.98
3.1
2.3
16.1
16.3
%
0.20
35
234
5
23
2.18
0.98
1.0
2.0
—
—
—
0
0
82
675
1.22
0.98
1.9
3.4
2.3
1.7
ratio
—
10
55
102
858
1.19
0.98
2.8
3.0
—
—
—
0
0
64
513
1.25
0.97
4.6
7.8
11.7
11.0
mmol/l
0.63
55
460
15
92
1.63
0.97
1.6
1.5
—
—
—
0
0
64
514
1.25
0.96
4.6
7.8
105.3
105.2
mmol/l
0.07
55
461
13
77
1.69
0.95
1.2
1.1
—
—
—
0
0
13
77
1.69
0.95
1.2
1.1
—
—
—
0
0
13
77
1.69
0.95
1.2
1.1
—
—
—
0
0
68
551
1.24
0.94
3.8
3.1
2.5
2.6
mmol/l
0.15
48
368
66
535
1.24
0.92
1.2
1.2
—
—
—
0
0
269
2439
1.11
0.91
3.8
4.1
0.1
0.2
%
0.89
67
583
6
28
2.14
0.91
1.0
2.3
—
9.3
—
0
7
66
536
1.24
0.91
1.1
1.2
—
—
—
0
0
16
243
0.66
0.90
1.1
1.2
—
—
—
0
0
84
704
1.20
0.86
1.9
3.4
44.9
45.1
mg/l
0.01
71
572
108
926
1.17
0.86
11.9
7.8
—
—
—
0
0
54
432
1.25
0.86
2.2
1.6
30.2
20.8
iu/ml
—
5
18
21
145
1.45
0.84
1.1
1.2
133.7
281.4
u/l
1.20
21
130
84
706
1.19
0.84
1.9
3.4
38.5
35.8
mg/l
0.15
71
573
32
240
1.34
0.82
1.4
1.4
6916.4
64662.6
e6/l
0.99
18
159
10
165
0.60
0.81
2.5
2.7
—
25.8
—
0
5
103
887
1.17
0.79
2.9
3.2
24.8
25.0
mmol/l
0.35
95
825
28
207
1.36
0.79
1.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
118
1347
0.87
0.76
1.4
1.4
—
—
—
0
0
0
28
0.00
0.76
0.0
2.8
—
—
—
0
0
202
1827
1.11
0.75
2.8
2.5
77.4
71.3
e9/l
1.62
153
1336
61
504
1.21
0.75
2.4
2.6
13.3
13.2
%
0.60
61
497
56
459
1.22
0.74
1.4
1.3
—
—
—
0
0
32
245
1.31
0.73
2.9
4.8
7.3
6.9
mmol/l
0.29
26
201
12
76
1.58
0.71
1.3
2.2
7345.0
33409.8
e6/l
—
6
41
37
467
0.79
0.71
1.5
1.4
70.0
63.5
mmol/l
0.39
31
367
186
1683
1.11
0.70
1.7
2.2
—
—
—
0
0
7
41
1.71
0.70
4.0
9.2
—
—
—
0
0
9
142
0.63
0.69
2.9
1.5
—
—
—
0
0
713
6811
1.06
0.69
2.1
1.9
—
—
—
0
0
14
204
0.69
0.68
1.1
1.8
7.4
3.3
mg/l
0.86
14
192
22
296
0.74
0.68
1.4
1.4
—
—
—
0
0
16
226
0.71
0.66
1.3
1.2
—
—
—
0
0
5
94
0.53
0.66
15.0
6.0
—
—
—
0
0
956
9218
1.05
0.66
1.6
1.5
—
—
—
0
0
11
70
1.57
0.65
1.2
1.4
49.3
40.2
%
0.36
11
55
256
2365
1.09
0.65
3.6
3.9
0.4
0.6
%
0.66
55
466
25
189
1.33
0.64
1.0
1.1
—
—
—
0
0
20
270
0.74
0.64
1.8
1.2
3.5
0.8
u/ml
0.38
11
100
266
2465
1.09
0.63
4.2
3.4
1.2
1.2
mmol/l
0.32
236
2125
12
177
0.68
0.63
2.5
2.6
1053.0
803.5
e6/l
—
5
77
309
3309
0.93
0.62
1.3
1.3
—
—
—
0
0
17
121
1.41
0.62
1.1
1.2
—
—
—
0
0
8
49
1.63
0.62
2.5
2.4
—
—
—
0
0
716
6865
1.05
0.62
1.3
1.4
2.3
2.2
g/l
1.32
432
4135
58
685
0.84
0.61
1.3
1.4
—
—
—
0
0
8
50
1.60
0.61
1.0
1.0
—
—
—
0
0
27
346
0.78
0.61
1.3
1.5
—
—
—
0
0
30
235
1.28
0.61
1.0
1.1
0.3
2.8
u/ml
—
5
67
253
2345
1.08
0.60
1.4
1.3
168.7
153.1
u/ml
0.18
235
2158
0
21
0.00
0.60
0.0
1.2
—
161.3
—
0
13
232
2504
0.92
0.58
2.4
2.4
18.5
23.5
au/ml
—
7
170
54
637
0.85
0.57
1.1
1.1
1.2
1.0
u/ml
0.14
19
257
6
35
1.72
0.57
1.0
1.2
—
—
—
0
0
848
8183
1.05
0.57
3.5
3.4
—
—
—
0
0
1116
11489
0.96
0.57
3.0
2.6
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
—
—
—
0
0
8
123
0.65
0.54
3.1
3.2
—
—
—
0
0
766
7387
1.05
0.53
2.2
2.0
—
—
—
0
0
316
2972
1.07
0.53
1.5
1.4
—
—
—
0
0
6
97
0.62
0.52
2.5
2.7
—
—
—
0
0
109
982
1.11
0.50
1.2
1.2
—
—
—
0
0
72
632
1.14
0.49
3.3
3.1
22.3
23.1
mg/l
0.08
52
370
144
1317
1.10
0.49
1.2
1.3
195.4
239.9
miu/ml
0.88
66
663
58
669
0.86
0.49
1.1
1.1
3.7
4.6
u/ml
0.26
26
328
239
2554
0.93
0.49
1.5
1.4
—
—
—
0
0
15
110
1.37
0.48
1.8
1.9
—
—
—
0
0
7
109
0.64
0.48
1.4
1.1
—
—
—
0
0
103
927
1.11
0.48
2.8
2.1
—
—
—
0
0
7
46
1.52
0.48
1.0
1.1
—
—
—
0
0
27
217
1.25
0.48
1.4
1.4
1293.4
3116.9
e6/l
1.61
21
157
41
345
1.19
0.47
2.5
2.0
36.4
394.7
u/ml
0.46
41
315
24
300
0.80
0.47
2.1
2.2
1.0
1.2
e9/l
1.10
18
188
60
522
1.15
0.47
1.1
1.6
0.5
0.7
g/l
1.06
48
382
51
438
1.17
0.47
2.6
2.8
34.7
32.7
umol/l
0.28
46
383
29
236
1.23
0.46
1.0
1.0
2.4
1.0
u/ml
—
6
56
116
1056
1.10
0.45
1.8
1.9
4.5
4.4
iu/l
0.05
43
399
61
534
1.14
0.45
1.6
3.5
—
—
—
0
0
73
821
0.89
0.44
1.2
1.2
10.4
13.9
u/l
1.81
64
682
47
544
0.86
0.43
1.2
1.1
—
—
—
0
0
47
544
0.86
0.43
1.2
1.1
—
—
—
0
0
25
306
0.82
0.42
1.8
2.6
—
—
—
0
0
5
32
1.56
0.42
1.2
1.1
—
—
—
0
0
5
33
1.52
0.41
1.8
1.0
—
—
—
0
0
8
60
1.33
0.40
1.3
1.6
15.9
13.4
g/l
—
8
50
0
18
0.00
0.40
0.0
1.2
—
19.1
—
0
11
7
103
0.68
0.39
9.6
1.6
—
—
—
0
0
7
103
0.68
0.39
1.1
2.1
0.4
1.2
ug/l
—
7
95
5
35
1.43
0.39
1.0
1.1
—
4.7
—
0
5
47
409
1.15
0.39
2.6
2.9
1.6
1.5
%
0.04
38
316
133
1437
0.92
0.39
1.4
1.7
531.1
307.7
mu/l
0.48
118
1270
11
80
1.38
0.38
1.0
1.1
—
—
—
0
0
28
334
0.84
0.38
1.1
1.2
—
—
—
0
0
35
409
0.85
0.38
1.1
1.1
—
—
—
0
0
91
828
1.10
0.38
2.5
2.9
—
—
—
0
0
27
323
0.83
0.38
2.3
2.9
—
—
—
0
0
9
67
1.34
0.38
1.1
1.1
—
—
—
0
0
10
72
1.39
0.36
1.2
1.1
—
—
—
0
0
244
2314
1.06
0.36
2.3
2.7
10.4
10.3
g/l
0.10
226
2117
36
309
1.17
0.36
1.2
1.2
—
—
—
0
0
414
4304
0.96
0.36
1.2
1.2
—
—
—
0
0
148
1383
1.07
0.35
1.5
1.7
—
—
—
0
0
35
301
1.16
0.35
1.4
1.4
—
—
—
0
0
35
301
1.16
0.35
1.4
1.4
—
—
—
0
0
35
301
1.16
0.35
1.4
1.4
—
—
—
0
0
35
301
1.16
0.35
1.4
1.4
—
—
—
0
0
1400
14237
0.97
0.34
2.0
2.0
—
—
—
0
0
73
805
0.90
0.34
1.1
1.1
—
—
—
0
0
23
190
1.21
0.34
1.4
1.4
8245.9
54879.7
e6/l
1.06
13
108
14
178
0.79
0.34
1.1
1.2
—
—
—
0
0
478
4620
1.04
0.33
1.2
1.2
—
—
—
0
0
380
3655
1.04
0.33
1.3
1.4
—
—
—
0
0
36
414
0.87
0.33
4.8
4.5
69.1
87.7
u/ml
—
10
120
2896
29143
0.97
0.32
14.7
12.9
39.0
39.2
%
0.51
2129
22049
218
2295
0.95
0.32
1.3
1.3
43.2
40.5
au/ml
—
9
92
38
434
0.87
0.32
1.0
1.0
0.1
0.1
u/ml
—
6
95
18
146
1.23
0.32
1.5
1.4
140.8
125.2
nmol/l
0.85
18
146
20
241
0.83
0.31
1.5
1.8
11.8
12.8
%
—
6
116
14
110
1.27
0.31
1.0
1.1
—
—
—
0
0
28
239
1.17
0.31
3.1
2.8
51.2
56.3
%
0.47
20
148
7
99
0.71
0.30
2.6
2.3
—
151.4
—
0
14
50
558
0.89
0.30
1.0
1.1
1.2
3.2
u/ml
2.49
20
264
81
744
1.09
0.30
1.1
1.1
—
—
—
0
0
260
2488
1.05
0.30
1.2
1.3
—
—
—
0
0
12
152
0.79
0.29
1.1
1.1
—
—
—
0
0
27
232
1.17
0.28
1.5
1.4
31.9
34.5
g/l
0.39
22
208
76
700
1.09
0.27
1.3
1.2
—
—
—
0
0
12
95
1.26
0.26
2.6
2.3
—
—
—
0
0
10
77
1.30
0.26
1.2
2.3
—
—
—
0
0
5
73
0.68
0.26
1.2
1.4
—
—
—
0
0
172
1637
1.05
0.26
2.2
2.4
—
—
—
0
0
82
762
1.08
0.25
1.9
2.0
37.3
38.3
g/l
0.81
76
666
14
170
0.82
0.25
1.1
1.1
1436.2
1526.7
miu/ml
0.15
14
170
10
78
1.28
0.24
1.2
2.0
—
—
—
0
0
6
84
0.71
0.24
1.0
1.0
—
—
—
0
0
14
169
0.83
0.24
1.6
1.3
—
—
—
0
0
21
180
1.17
0.23
1.5
1.7
1.2
1.1
promille
0.07
14
138
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
10
125
0.80
0.23
2.2
2.1
48.1
55.2
umol/l
—
10
96
36
399
0.90
0.21
1.3
1.5
—
—
—
0
0
2095
21112
0.98
0.21
3.1
2.9
41.6
38.5
u/l
1.15
1979
19740
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
124
1179
1.05
0.21
2.5
2.0
—
—
—
0
0
8
105
0.76
0.21
1.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
554.3
—
0
13
0
13
0.00
0.21
0.0
1.5
—
23.8
—
0
13
28
249
1.13
0.20
1.1
1.1
—
—
—
0
0
57
615
0.93
0.20
1.1
1.1
0.5
1.5
u/ml
1.13
11
141
23
261
0.88
0.20
7.4
6.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
526
5373
0.98
0.20
2.6
2.7
2.5
2.4
mmol/l
1.06
447
4700
126
1201
1.05
0.20
2.5
2.1
—
—
—
0
0
125
1192
1.05
0.19
2.5
2.1
—
—
—
0
0
14
165
0.85
0.19
2.4
3.4
—
—
—
0
0
115
1095
1.05
0.19
2.6
2.1
—
—
—
0
0
23
203
1.13
0.19
1.0
1.1
—
—
—
0
0
7
58
1.21
0.18
2.0
1.9
—
—
—
0
0
17
147
1.16
0.18
1.9
2.1
2.1
3.3
ug/l
0.66
17
126
70
658
1.07
0.18
3.2
3.7
57.1
57.1
%
0.00
70
658
125
1196
1.05
0.18
2.5
1.9
—
—
—
0
0
1035
10478
0.98
0.18
3.1
3.3
2.4
2.4
mmol/l
0.43
922
9173
5
66
0.76
0.17
1.8
1.8
—
—
—
0
0
8
68
1.18
0.16
1.1
1.1
—
—
—
0
0
8
70
1.14
0.16
2.3
1.2
—
—
—
0
0
16
183
0.87
0.16
2.2
3.3
—
—
—
0
0
136
1413
0.96
0.16
1.2
1.2
—
—
—
0
0
13
111
1.17
0.15
1.0
1.7
—
—
—
0
0
55
516
1.07
0.15
1.3
1.6
—
—
—
0
0
7
88
0.80
0.14
1.7
1.5
—
—
—
0
0
48
512
0.94
0.14
1.7
1.3
—
—
—
0
0
17
150
1.13
0.14
2.0
2.0
3.2
3.9
ug/l
0.15
17
137
230
2360
0.97
0.14
1.3
1.3
26.7
29.0
iu/l
0.57
210
2059
72
757
0.95
0.14
1.2
1.1
2.9
1.0
u/ml
0.35
21
281
12
139
0.86
0.14
1.1
1.1
—
—
—
0
0
29
266
1.09
0.14
2.4
3.5
—
—
—
0
0
17
190
0.89
0.13
1.5
1.4
—
—
—
0
0
11
127
0.87
0.12
1.3
1.1
—
—
—
0
0
47
498
0.94
0.12
1.1
1.1
1.9
3.7
u/ml
0.66
17
192
58
551
1.05
0.12
3.9
2.7
—
—
—
0
0
22
241
0.91
0.12
1.6
1.3
—
—
—
0
0
69
722
0.95
0.12
1.3
1.4
22.6
29.5
e6/l
0.22
55
541
69
722
0.95
0.12
1.4
1.4
135.3
1352.5
e6/l
2.24
56
578
20
220
0.91
0.12
1.2
1.3
—
—
—
0
0
364
3579
1.02
0.11
1.3
1.3
—
—
—
0
0
60
572
1.05
0.11
3.4
3.5
87.8
791.0
u/ml
0.89
53
521
33
353
0.93
0.11
1.3
1.4
—
—
—
0
0
73
761
0.96
0.11
1.4
1.7
—
—
—
0
0
272
2768
0.98
0.10
3.9
3.5
32.8
49.7
u/ml
2.22
266
2671
5
46
1.09
0.09
1.0
1.4
—
—
—
0
0
6
57
1.05
0.08
1.2
1.1
—
—
—
0
0
59
613
0.96
0.08
1.1
1.2
—
—
—
0
0
297
3013
0.98
0.08
3.2
3.8
16.7
37.1
ug/l
0.55
223
2323
7
64
1.09
0.08
2.4
2.1
12.5
17.1
umol/l
—
7
64
18
195
0.92
0.08
1.1
1.2
—
—
—
0
0
26
244
1.07
0.08
1.1
1.1
20.9
8.7
iu/ml
—
5
65
12
108
1.11
0.07
3.7
2.6
—
—
—
0
0
90
877
1.03
0.07
1.3
1.3
30.6
42.6
u/ml
0.57
12
103
292
2884
1.01
0.07
2.4
2.2
63.4
37.3
u/l
0.38
241
2433
8
91
0.88
0.06
1.4
1.3
—
—
—
0
0
14
129
1.09
0.05
1.6
3.3
—
—
—
0
0
107
1051
1.02
0.05
1.0
1.1
2.7
6.6
u/ml
1.13
12
136
17
181
0.94
0.05
1.4
1.4
—
—
—
0
0
37
383
0.97
0.04
1.4
1.5
—
—
—
0
0
13
121
1.07
0.03
1.2
1.1
—
471.3
—
0
26
13
121
1.07
0.03
1.4
1.9
—
—
—
0
0
17
179
0.95
0.03
2.3
2.4
0.1
0.4
e9/l
0.70
17
173
18
172
1.05
0.02
3.4
3.7
—
—
—
0
0
11
103
1.07
0.02
1.6
1.6
—
—
—
0
0
18
173
1.04
0.01
1.5
1.4
—
—
—
0
0
124
1231
1.01
0.01
1.8
1.8
—
—
—
0
0
24
247
0.97
0.01
1.1
1.1
1.0
1.0
ratio
—
5
84
294
2949
1.00
0.01
1.2
1.2
—
—
—
0
0
53
537
0.99
0.01
1.1
1.0
5.7
3.6
u/ml
0.16
16
200
371
3701
1.00
0.01
1.4
1.4
—
—
—
0
0
11
104
1.06
0.01
1.3
1.1
—
—
—
0
0
12
122
0.98
0.00
1.2
1.2
—
0.4
g/l
—
0
9
19
192
0.99
0.00
1.1
1.2
—
—
—
0
0
24
238
1.01
0.00
1.0
1.0
—
—
—
0
0
48
482
1.00
0.00
1.2
1.1
—
—
—
0
0
24
245
0.98
0.00
1.2
1.6
30.2
38.7
%
0.52
16
135
35
345
1.01
0.00
1.3
1.6
45.3
53.9
%
0.58
24
206
129
1295
1.00
0.00
1.0
1.1
—
—
—
0
0
46
464
0.99
0.00
1.2
1.2
—
—
—
0
0
29
286
1.01
0.00
1.1
1.1
—
—
—
0
0
96
957
1.00
0.00
3.2
3.4
1099.7
497.1
u/ml
0.37
80
812
25
253
0.99
0.00
1.1
1.1
349.9
392.4
nmol/l
0.45
18
228
0
6
0.00
0.00
0.0
2.8
—
9.3
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
1226.7
—
0
6
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.3
—
0
7
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
6
62
0.97
0.00
1.5
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
0.1
—
0
5
0
6
0.00
0.00
0.0
1.0
—
0.3
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
55
0.91
0.00
1.0
2.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
112.1
—
0
7

Mortality – FinRegistry

Association

Association between endpoint O15_GESTAT_OEDEM_PREINUR and mortality.

Females

Parameter HR [95% CI] p-value
O15_GESTAT_OEDEM_PREINUR 0.781 [0.61, 1.0] 0.049
Birth year 1.0 [0.99, 1.01] 0.905

During the follow-up period (1.1.1998 — 31.12.2019), 76 out of 9505 females with O15_GESTAT_OEDEM_PREINUR died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_GESTAT_OEDEM_PREINUR.

N-year risk Females Males
1 0.092% No data
5 0.551% No data
10 1.401% No data
15 2.607% No data
20 4.687% No data

Relationships between endpoints

Index endpoint: O15_GESTAT_OEDEM_PREINUR – Gestational [pregnancy-induced] oedema and proteinuria without hypertension

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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