This is a non-core endpoint: only basic statistics are computed.
See its core counterpart CD2_INSITU_CERVIX_UTERI_EXALLC for full statistics.
Carcinoma in situ of cervix uteri
CD2_INSITU_CERVIX_UTERI
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditions
|
292812 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
3860 |
4. Check minimum number of eventsNone |
3860 |
5. Include endpoints |
3866 |
6. Filter based on genotype QC (FinnGen only) |
3866 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- D00-D09
- Name in latin
- Carcinoma in situ vaginae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of cervix uteri
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of cervix uteri
- In situ neoplasms
- In situ neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3866 | 3866 | - |
| Unadjusted period prevalence (%) | 1.32 | 1.32 | - |
| Median age at first event (years) | 35.40 | 35.40 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3487
- Matched controls
- 34871
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
81.7
323.0
2394
909
LDA10
NOMESCO Finland
Curettage of cervix uteri
16.3
323.0
1146
1018
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
+∞
323.0
633
*
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
153.1
323.0
2099
340
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
23.7
323.0
2461
3208
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
9098.7
323.0
2451
7
ULA02
NOMESCO Finland
Kolposcopy
36.9
323.0
2720
3061
N87.1
ICD-10 Finland
Moderate cervical dysplasia
22.2
323.0
875
518
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
24.8
323.0
2117
2041
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
15.7
323.0
2287
3767
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
413.3
323.0
339
9
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
1212.4
235.0
227
*
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
1669.8
160.6
155
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
6.2
141.4
407
722
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
1425.5
140.6
136
*
LEB00
NOMESCO Finland
Biopsy of vagina
9.2
105.3
230
267
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
268.4
102.3
104
*
2331A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Cervix uteri
+∞
94.2
90
*
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
7.7
89.9
217
296
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.0
87.7
1751
11500
23400
ICD-8 Finland
Neoplasm of unspecified nature of uterus, Carcinoma in situ of cervix uteri
+∞
84.7
81
*
ZXC00
NOMESCO Finland
Use of diathermy
14.8
73.9
126
88
8326
FHL
Batch conization
28.2
70.0
96
35
18099
ICD-8 Finland
Malignant neoplasm of cervix uteri
+∞
67.9
65
*
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
16.9
65.0
105
64
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
51.4
736
4028
X86
ICPC
Abnormal cervix smear
5.4
39.9
124
237
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
9.4
35.5
74
80
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
5.5
35.3
107
199
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.6
35.3
278
1132
LCA06
NOMESCO Finland
Biopsy of endometrium
1.9
32.4
566
3271
G01AA10
ATC
clindamycin; vaginal
1.7
32.3
786
5057
8140/2-C53.1
ICD-O-3
Adenocarcinoma in situ, NOS, of exocervix
+∞
32.3
31
*
8140/2-C53.0
ICD-O-3
Adenocarcinoma in situ, NOS, of endocervix
+∞
31.3
30
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.6
31.2
148
428
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
24.4
29.2
41
17
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
13.9
28.0
48
35
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
31.2
25.9
34
11
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
58.5
25.0
29
5
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
26.4
24.8
34
13
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
19.7
24.7
37
19
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
7.5
24.1
57
77
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
16.5
22.7
36
22
18000
ICD-8 Finland
NA
+∞
21.9
21
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
21.4
214
982
SPAT1193
SPAT
Pap smear
1.6
20.8
623
4183
N89.0
ICD-10 Finland
Mild vaginal dysplasia
7.0
18.8
46
66
TLC02
NOMESCO Finland
Simple extraction of IUD
2.0
18.8
244
1254
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
2.4
18.3
164
715
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
16.7
108
393
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
+∞
16.7
16
*
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
13.4
16.4
28
21
SPAT1263
SPAT
Sampling
1.4
16.4
1412
11621
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
9.8
16.1
32
33
P01AB01
ATC
metronidazole; oral, rectal
1.4
16.1
1391
11442
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
2.4
15.0
128
543
N90.0
ICD-10 Finland
Mild vulvar dysplasia
7.0
14.8
36
52
X23
ICPC
Fear sexually transm dis female
1.7
14.6
337
2103
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
9.7
14.2
28
29
N07BA03
ATC
varenicline; oral
2.0
14.1
177
900
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
9.1
13.2
27
30
LCD10
NOMESCO Finland
Vaginal hysterectomy
2.3
12.8
117
517
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
11.0
12.5
23
21
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
2.1
11.9
135
659
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
11.8
352
2342
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.4
11.5
505
3653
N87
ICD-10 Finland
Dysplasia of cervix uteri
11.1
11.5
21
19
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
25.1
11.1
15
6
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
2.0
11.1
132
658
N76.0
ICD-10 Finland
Acute vaginitis
1.5
11.1
342
2294
WX110
NOMESCO Finland
Local anesthesy
1.3
11.1
2344
21398
X92
ICPC
Chlamydia infection genital female
2.3
10.5
91
396
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.8
10.4
167
933
D06BB04
ATC
podophyllotoxin; topical
1.6
10.2
253
1609
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.3
9.9
87
382
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
8.1
9.8
21
26
W11
ICPC
Contraception oral
1.4
9.8
556
4212
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
2.3
9.7
88
390
X85
ICPC
Cervical disease NOS
13.4
9.7
16
12
SPAT1301
SPAT
No procedures
1.3
9.7
876
7127
8077/2-C53.0
ICD-O-3
Squamous intraepithelial neoplasia, high grade of endocervix
100.3
9.4
10
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
9.2
275
1828
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
9.0
1322
11425
N93.0
ICD-10 Finland
Postcoital and contact bleeding
2.9
8.9
51
175
SPAT1312
SPAT
General health counselling
1.3
8.8
1047
8809
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
6.6
8.6
21
32
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
11.6
8.6
15
13
SPAT1308
SPAT
Sexual health counselling
1.3
8.3
762
6197
D06BB10
ATC
imiquimod; topical
1.8
8.2
145
838
4044
NOMESCO Finland
NA
11.7
8.1
14
12
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
8.0
2446
22780
D82
ICPC
Teeth/gum disease
1.2
7.3
1181
10244
T74.1
ICD-10 Finland
Physical abuse
2.1
7.3
75
357
T810, N872
ICD-10 Finland
NA
+∞
7.3
7
*
D06.7
ICD-10 Finland
Carcinoma in situ: Other parts of cervix
+∞
7.3
7
*
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.1
7.3
81
396
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
4.5
7.1
23
51
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
7.5
6.9
15
20
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
6.9
1732
15691
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
6.8
981
8391
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
6.7
187
1225
N06AX11
ATC
mirtazapine; oral
1.2
6.7
881
7461
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
4.3
6.5
22
51
SPAT1283
SPAT
Restricted health certificate
1.2
6.5
840
7094
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
2.5
6.5
49
200
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
6.5
248
1745
SPAT1238
SPAT
Brief therapy
1.9
6.4
89
477
LCH11
NOMESCO Finland
Pharmacologic abortion
1.5
6.4
244
1718
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
5.9
6.3
16
27
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.2
6.2
774
6514
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_CERVIX_UTERI – Carcinoma in situ of cervix uteri
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).