Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery

P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P00-P04 Cause of death: ICD-10 — P00-P04 2 out of 7 registries used, show all original rules.	506
4. Check minimum number of events None	506
5. Include endpoints P16_FET_NEWB_MATERN_COND_UNREL_PRESENT_PREGNAC P16_FET_NEWB_MATERN_COMPLICATIO_PREGNAC P16_FET_NEWB_COMPLICATIO_PLACEN_CORD_MEMBRANES P16_FET_NEWB_OTH_COMPLICATIO_LABOUR_DELIV P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK	506
6. Filter based on genotype QC (FinnGen only)	506

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 2
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P
Name in latin: Fetus et neonatus factoribus maternis atque complicationibus graviditatis, laborum et partus affectus

NAME	P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	P16_FET_NEWB_MATERN_COND_UNREL_PRESENT_PREGNAC\|P16_FET_NEWB_MATERN_COMPLICATIO_PREGNAC\|P16_FET_NEWB_COMPLICATIO_PLACEN_CORD_MEMBRANES\|P16_FET_NEWB_OTH_COMPLICATIO_LABOUR_DELIV\|P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P0[0-4]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P0[0-4]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	43198	19780	23410
Only index persons	16855	7854	9001
Unadjusted period prevalence (%)
Whole population	0.61	0.57	0.65
Only index persons	0.32	0.29	0.34
Median age at first event (years)
Whole population	0.01	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	506	277	229
Unadjusted period prevalence (%)	0.10	0.09	0.10
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
443: Matched controls
4344

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P07.3

ICD-10 Finland

Other preterm infants

24.5

122.5

183

121

P01.5

ICD-10 Finland

Fetus and newborn affected by multiple pregnancy

+∞

98.0

P00.0

ICD-10 Finland

Fetus and newborn affected by maternal hypertensive disorders

+∞

96.9

P01.10

ICD-10 Finland

Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery

+∞

82.4

Z87.6

ICD-10 Finland

Personal history of certain conditions arising in the perinatal period

13.9

78.2

145

147

P03.4

ICD-10 Finland

Fetus and newborn affected by caesarean delivery

+∞

41.0

P07.11

ICD-10 Finland

Other low birth weight 1500-1999 g

23.2

28.5

P07.12

ICD-10 Finland

Other low birth weight 2000-2499 g

13.4

26.7

P70.4

ICD-10 Finland

Other neonatal hypoglycaemia

8.5

25.3

P00.8

ICD-10 Finland

Fetus and newborn affected by other maternal conditions

+∞

22.9

P02.1

ICD-10 Finland

Fetus and newborn affected by other forms of placental separation and haemorrhage

+∞

20.8

WX722

NOMESCO Finland

PEEP

6.3

20.7

P59.0

ICD-10 Finland

Neonatal jaundice associated with preterm delivery

9.4

20.6

P39.9

ICD-10 Finland

Infection specific to the perinatal period, unspecified

12.4

18.4

AA5HE

NOMESCO Finland

Brain ultrasound examination in a child

4.1

17.5

200

P05.1

ICD-10 Finland

Small for gestational age

10.5

17.0

P22.1

ICD-10 Finland

Transient tachypnoea of newborn

6.2

16.4

P05.0

ICD-10 Finland

Light for gestational age

15.8

16.2

P07.1

ICD-10 Finland

Other low birth weight

30.8

16.1

P07.2

ICD-10 Finland

Extreme immaturity

17.9

13.8

P02.7

ICD-10 Finland

Fetus and newborn affected by chorioamnionitis

+∞

13.5

WW805

NOMESCO Finland

Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse

22.9

12.9

P03.0

ICD-10 Finland

Fetus and newborn affected by breech delivery and extraction

+∞

12.5

P00.2

ICD-10 Finland

Fetus and newborn affected by maternal infectious and parasitic diseases

+∞

12.5

P03.3

ICD-10 Finland

Fetus and newborn affected by delivery by vacuum extractor [ventouse]

+∞

12.5

P22.0

ICD-10 Finland

Respiratory distress syndrome of newborn

9.9

12.2

P04.1

ICD-10 Finland

Fetus and newborn affected by other maternal medication

+∞

11.4

P70.0

ICD-10 Finland

Syndrome of infant of mother with gestational diabetes

6.5

11.4

602

Kela drug reimbursment

Children's severe malnutrition

3.7

11.3

149

P07.10

ICD-10 Finland

Other low birth weight 1000-1499 g

16.9

9.8

P27.1

ICD-10 Finland

Bronchopulmonary dysplasia originating in the perinatal period

11.5

9.5

H35.1

ICD-10 Finland

Retinopathy of prematurity

17.7

9.4

P04.4

ICD-10 Finland

Fetus and newborn affected by maternal use of drugs of addiction

+∞

9.3

P03.1

ICD-10 Finland

Fetus and newborn affected by other malpresentation, malposition and disproportion during labour and delivery

+∞

9.3

A11JC

ATC

Vitamins, other combinations

14.1

8.6

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

2.2

8.5

459

P04.2

ICD-10 Finland

Fetus and newborn affected by maternal use of tobacco

+∞

8.3

P70.1

ICD-10 Finland

Syndrome of infant of a diabetic mother

8.6

8.3

WX882

NOMESCO Finland

High dependency care

2.2

8.0

400

P22.8

ICD-10 Finland

Other respiratory distress of newborn

8.5

7.8

R4110

NOMESCO Finland

Physiotherapy

1.9

7.5

129

769

P22.9

ICD-10 Finland

Respiratory distress of newborn, unspecified

5.1

7.4

P01.11

ICD-10 Finland

Fetus and newborn affected by premature rupture of membranes more than 7 days before delivery

+∞

7.3

P21.0

ICD-10 Finland

Severe birth asphyxia

11.0

6.2

P02.6

ICD-10 Finland

Fetus and newborn affected by other and unspecified conditions of umbilical cord

+∞

6.2

RK312

NOMESCO Finland

7.0

6.2

P36.90

ICD-10 Finland

Suspected bacterial sepsis of newborn

4.5

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3026820) Hemoglobin [Mass/volume] in Venous cord blood

5.04

6.15

1.0

162.8

163.2

g/l

0.01

(3022670) pH of Venous cord blood

3.32

4.97

1.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

3.01

2.92

1.1

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

193

1.79

2.52

1.9

1.4

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

193

1.79

2.52

1.9

1.4

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

2.47

2.41

1.3

1.2

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

2.46

2.23

1.1

—

(40765089) Chromosome analysis panel - Blood by G-banded

2.23

1.0

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

139

1120

1.31

1.94

15.9

12.0

0.8

mmol/l

0.08

101

812

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

2.09

1.82

1.0

1.1

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

234

2033

1.26

1.76

5.0

5.6

154.6

135.4

u/l

1.98

228

1903

(3008898) HLA-B27 [Presence]

192

0.45

1.76

1.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

304

1.51

1.76

1.4

—

(3022313) Gas panel - Capillary blood

124

1002

1.30

1.68

16.2

11.9

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

105

837

1.30

1.58

4.2

4.3

2.1

2.4

e6/l

0.22

484

(3000570) Elastase.pancreatic [Mass/mass] in Stool

106

1.80

1.55

1.2

1.3

446.0

385.4

ug/g

—

(3008092) Baker's yeast IgG Ab [Units/volume] in Serum

0.00

1.52

0.0

1.2

—

18.7

—

(3004593) Baker's yeast IgA Ab [Units/volume] in Serum

0.00

1.52

0.0

1.2

—

30.6

—

(3048689) Calprotectin [Mass/mass] in Stool

867

0.74

1.52

2.1

3.1

62.7

89.0

ug/g

0.84

699

(3032080) INR in Blood by Coagulation assay

790

0.73

1.51

3.1

5.1

1.1

inr

0.38

193

(3024891) Influenza virus A+B Ag [Presence] in Specimen

267

1.48

1.46

1.7

1.3

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

120

986

1.27

1.42

11.3

13.4

1.5

1.4

mmol/l

2.20

114

945

(3002582) Erythrocytes [#/volume] in Urine

159

1350

1.24

1.42

5.3

5.2

15.1

23.4

e6/l

0.95

117

1012

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

377

0.64

1.40

1.2

1.1

7.0

u/ml

—

106

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

164

1399

1.23

1.40

6.2

5.3

—

(21494815) CD4 cells/100 lymphocytes in Specimen

163

0.48

1.37

2.5

3.9

—

(3030467) Casts [#/volume] in Urine by Automated count

151

1279

1.24

1.37

5.1

4.9

0.2

e6/l

0.06

109

946

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

157

1.60

1.37

1.8

—

(3026008) Bacteria identified in Urine by Culture

107

873

1.27

1.34

3.1

2.6

—

(3041672) Baker's yeast Ab [Presence] in Serum

0.00

1.34

0.0

1.2

—

(3023410) Appearance of Cerebral spinal fluid

145

0.47

1.34

2.0

5.8

—

(3028626) Oxygen [Partial pressure] in Capillary blood

126

1050

1.25

1.32

16.4

11.9

9.4

9.7

kpa

1.08

120

1016

(3037522) Nuclear Ab [Titer] in Serum

508

0.70

1.31

1.7

1.6

293.3

524.2

titre

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

234

2080

1.21

1.31

7.8

9.3

6.0

5.9

mmol/l

0.12

220

1946

(3022217) INR in Platelet poor plasma by Coagulation assay

1.78

1.30

1.5

12.0

1.0

1.4

inr

—

(4306422)

1.97

1.29

1.0

1.1

—

(3022145) Colonoscopy Study observation

189

0.51

1.29

1.7

1.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

606

0.72

1.28

2.3

2.0

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

390

0.67

1.25

1.2

13.8

18.1

iu/ml

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

222

1971

1.20

1.24

15.9

15.5

1.2

mmol/l

0.02

206

1848

(3002256) Pathology report gross observation

260

0.60

1.24

1.3

1.2

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

166

0.53

1.21

2.3

3.8

—

(3027831) CD3-CD16+CD56+ (Natural killer) cells/100 cells in Blood

168

0.52

1.20

2.3

3.7

16.1

9.1

—

158

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

100

821

1.25

1.20

4.4

4.2

0.6

0.9

e6/l

1.16

467

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

139

1.59

1.20

1.5

1.4

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.04

1.19

1.2

1.7

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

1.15

0.0

1.0

—

(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative

0.00

1.15

0.0

1.1

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

291

1.39

1.13

2.2

1.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

106

883

1.24

1.12

2.6

3.9

—

(3044640) Blood type and Crossmatch panel - Blood

120

1013

1.22

1.12

2.6

4.1

—

(3005719) IgG [Mass/volume] in Serum or Plasma

514

0.73

1.10

2.3

4.6

8.7

8.5

g/l

0.16

497

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

163

0.54

1.10

2.9

3.0

—

(3018095) Leukocytes [#/volume] in Urine

179

1573

1.19

1.10

6.7

6.0

54.8

56.4

e6/l

0.02

122

1051

(36304419) Bacteria [Presence] in Urine

149

1288

1.20

1.09

5.0

4.8

—

(3013727) Leukocytes other/100 leukocytes in Blood

2.37

1.07

1.2

8.4

45.1

38.0

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

1.95

1.03

1.6

1.4

—

(3011648) Oxygen content in Venous blood

108

0.45

1.01

9.8

27.5

11.1

11.4

—

108

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.98

0.0

1.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.98

0.0

1.4

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.98

0.0

1.4

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.97

0.0

1.5

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.96

0.0

1.5

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.96

0.0

1.5

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

170

0.57

0.95

1.5

5.0

3.6

3.2

mmol/l

—

163

(1761482) Bacteria [#/volume] in Urine by Culture

1.88

0.93

1.9

1.8

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

2.13

0.91

1.3

1.1

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

213

1924

1.16

0.91

16.6

16.8

1.2

mmol/l

0.47

204

1846

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

117

1.54

0.90

5.9

2.2

2.5

ug/l

0.27

117

(3026782) Osmolality of Urine

102

866

1.21

0.90

3.7

3.9

576.4

595.6

mosm/kgh2o

0.27

752

(3000850) Epithelial cells [#/volume] in Urine

103

879

1.20

0.87

4.3

4.1

6.0

6.7

e6/l

0.27

775

(3016018) Differential panel - Cerebral spinal fluid

114

0.51

0.83

1.7

4.7

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

114

0.51

0.83

1.8

1.4

—

(3006598) pH of Arterial cord blood

264

1.33

0.83

1.0

—

(3004959) Base excess in Arterial cord blood by calculation

264

1.33

0.83

1.0

-3.6

-2.3

mmol/l

—

(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood

264

1.33

0.83

1.0

7.6

7.2

kpa

0.41

221

(3023368) Bacteria identified in Blood by Culture

688

1.21

0.83

3.9

4.6

—

(3019225) pH of Specimen

120

1.50

0.82

8.7

5.9

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

121

1.49

0.80

1.5

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

121

1.49

0.80

1.5

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

121

1.49

0.80

1.5

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

121

1.49

0.80

1.5

1.4

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

252

0.69

0.76

4.3

2.4

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

1.53

0.75

1.6

1.4

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

1.69

0.75

1.0

1.1

84.0

91.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

2.07

0.74

1.0

1.1

—

(3000330) Specific gravity of Urine by Test strip

115

1.48

0.74

2.1

2.0

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

194

1764

1.14

0.73

3.7

3.2

35.6

36.1

mmol/mol

0.20

181

1657

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.59

0.72

2.2

2.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

221

2028

1.14

0.72

2.1

2.0

—

(3021706) Oxygen [Partial pressure] in Arterial cord blood

262

1.30

0.71

1.0

2.7

3.4

kpa

2.44

219

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

143

1275

1.15

0.71

6.0

10.1

41.1

29.0

umol/l

1.41

130

1164

(3019230) Fractional oxyhemoglobin in Venous blood

143

0.61

0.70

6.7

22.9

71.1

72.2

—

143

(40768797) Stomach Pathology biopsy report

270

0.72

0.70

1.3

1.5

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

1.91

0.70

1.0

1.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

402

0.77

0.70

1.5

1.7

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

1.66

0.68

5.1

8.6

1.4

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

614

1.18

0.63

10.9

16.3

0.8

mmol/l

0.13

595

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

187

1988

0.89

0.63

3.0

4.3

mmol/l

0.09

177

1886

(3015377) Calcium [Moles/volume] in Serum or Plasma

102

896

1.16

0.63

3.3

3.1

2.4

mmol/l

0.49

819

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

341

0.77

0.62

1.4

1.3

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

1.47

0.61

1.5

1.4

—

(3005033) Fetal Nuchal fold Thickness US

1.47

0.61

1.5

1.4

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

136

0.65

0.61

2.9

1.9

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

1.65

0.60

1.0

1.2

—

(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay

0.00

0.60

0.0

1.2

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

155

1.35

0.60

2.0

2.1

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.60

0.0

1.4

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

0.59

0.0

1.2

—

103.9

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.59

0.0

1.8

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

148

0.66

0.58

3.2

6.2

108.2

94.5

—

148

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

148

0.66

0.58

1.1

1.2

—

(1616796) Gas panel - Central venous blood

1.47

0.58

6.8

7.6

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

182

1930

0.89

0.58

2.9

2.8

1.4

mmol/l

0.02

170

1816

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.45

0.55

2.2

1.9

—

(3021440) Promyelocytes/100 leukocytes in Blood

228

1.27

0.55

7.7

6.4

0.1

0.0

0.47

(3024980) IgG subclass 4 [Mass/volume] in Serum

120

0.65

0.55

1.9

1.5

1.0

0.7

g/l

—

102

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

537

0.83

0.55

1.2

—

72.8

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

132

1.36

0.54

1.4

1.9

—

(3016879) Cocaine [Presence] in Urine

462

0.82

0.54

1.5

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

536

0.83

0.54

2.0

1.6

—

(3024928) Oxygen saturation in Venous blood

145

0.67

0.54

6.2

22.3

—

(3045424) Erythrocytes [Presence] in Urine

1.57

0.54

1.7

1.8

—

(42870588) Differential panel, method unspecified - Blood

217

2018

1.11

0.53

7.6

11.0

—

(42870560) Thyrotropin [Units/volume] in Cord blood

348

1.21

0.52

1.0

9.2

8.6

mu/l

0.13

301

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

1.40

0.51

1.1

—

(3027944) Amphetamines [Presence] in Urine

490

0.83

0.51

1.5

1.7

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.44

0.49

1.1

1.4

—

(3044290) Cell count panel - Cerebral spinal fluid

164

0.72

0.48

1.8

5.4

—

(3037121) Protein [Mass/volume] in Urine

278

1.22

0.48

10.1

8.9

0.3

g/l

0.18

233

(3018418) pH of Serum or Plasma

772

1.14

0.48

4.4

4.2

7.4

0.14

126

(3002179) Metamyelocytes/100 leukocytes in Blood

224

1.25

0.48

7.4

5.5

0.8

0.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

160

1692

0.90

0.47

3.6

5.2

24.7

26.9

u/l

0.45

153

1625

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

757

0.87

0.47

2.1

1.7

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

528

0.85

0.47

5.8

9.1

4.8

6.4

umol/l

0.97

435

(3015736) pH of Urine

139

1271

1.11

0.47

4.1

3.5

—

(3020891) Body temperature

0.61

0.46

15.8

9.3

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

991

0.89

0.46

3.9

6.0

32.8

35.2

u/l

0.36

949

(3045414) Leukocytes [Presence] in Urine

128

1.32

0.45

1.5

1.8

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

1.46

0.45

1.3

1.2

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

303

0.81

0.44

1.8

2.5

21.8

30.4

u/l

1.63

245

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

186

1946

0.91

0.44

3.0

2.8

2.6

mmol/l

0.48

175

1820

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

183

0.75

0.44

1.4

1.3

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

125

0.71

0.44

3.8

2.7

—

(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum

323

0.82

0.43

2.6

2.2

235.1

167.9

u/ml

0.46

149

(3023430) Cat dander IgE Ab [Units/volume] in Serum

237

0.78

0.43

1.1

1.2

18.6

11.1

u/ml

0.34

143

(40768804) Tissue Pathology biopsy report

751

0.88

0.43

1.8

1.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1058

0.89

0.43

3.1

2.6

—

(4035726)

215

0.77

0.43

1.8

1.9

—

(3035350) Ketones [Presence] in Urine by Test strip

171

1588

1.10

0.42

4.2

3.8

0.0

estimate

0.00

264

(3014133) Dog dander IgE Ab [Units/volume] in Serum

258

0.80

0.42

1.0

1.1

11.6

8.2

u/ml

0.22

150

(3025018) Bordetella pertussis Ab [Titer] in Serum

165

1.27

0.42

1.2

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

1.55

0.42

1.0

1.2

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

1.37

0.41

6.4

4.9

28.0

25.6

ug/l

—

(3009261) Glucose [Presence] in Urine by Test strip

171

1591

1.09

0.41

4.2

3.8

0.0

estimate

0.00

276

(723473) SARS-CoV-2 (COVID-19) IgA Ab [Presence] in Serum or Plasma by Immunoassay

0.00

0.40

0.0

1.2

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.32

0.40

2.3

1.3

—

(3020393) Adenovirus Ag [Presence] in Stool

131

1.29

0.39

1.7

2.1

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

223

0.79

0.39

1.0

1.1

0.0

0.5

u/ml

—

109

(4010399)

194

1.23

0.39

1.4

1.5

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

393

3966

0.91

0.39

12.5

12.0

21.0

23.5

mg/l

0.80

282

2672

(3003327) Ova and parasites identified in Stool by Light microscopy

287

0.82

0.39

1.8

—

(3027008) Opiates [Presence] in Urine

497

0.86

0.38

1.4

1.7

—

(3017181) Myelocytes/100 leukocytes in Blood

240

1.21

0.38

7.7

6.3

1.3

0.4

0.82

(3020874) Milk IgE Ab [Units/volume] in Serum

211

0.79

0.38

1.6

3.2

4.1

u/ml

0.13

157

(40768446) Kidney Pathology biopsy report

1.33

0.38

2.4

2.7

—

(3037467) Urinalysis macro (dipstick) panel - Urine

243

2302

1.08

0.37

5.7

4.6

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

454

0.86

0.37

2.6

4.1

2516.1

1223.1

ng/l

0.37

266

(3020630) Protein [Mass/volume] in Serum or Plasma

156

0.75

0.37

2.9

4.0

61.1

63.0

g/l

0.27

149

(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.31

0.37

8.2

10.4

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

327

0.84

0.36

2.5

2.2

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

155

0.76

0.36

1.4

1.2

—

(3019069) Monocytes/100 leukocytes in Blood

260

2473

1.08

0.36

7.6

10.7

8.4

8.3

0.03

250

2368

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

175

1821

0.92

0.36

1.8

2.3

4.1

u/ml

1.03

302

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

233

1.20

0.36

2.3

2.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

169

1581

1.08

0.35

6.3

5.6

0.0

estimate

0.00

281

(3014373) Corynebacterium diphtheriae Ab [Units/volume] in Serum

1.42

0.35

1.5

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

280

2673

1.08

0.35

8.7

12.4

3.3

3.5

e9/l

0.42

226

2194

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

1.38

0.35

1.0

1.3

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

373

1.15

0.34

3.2

2.4

740.8

5537.6

u/l

—

(3000764) Benzodiazepines [Presence] in Urine

492

0.87

0.34

1.4

1.7

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

152

1.24

0.34

2.2

2.1

—

(3013115) Eosinophils [#/volume] in Blood

271

2585

1.08

0.34

8.0

11.4

0.2

e9/l

2.50

226

2171

(3021960) Folate [Moles/volume] in Serum or Plasma

430

1.14

0.34

1.6

1.4

23.9

20.6

nmol/l

0.78

373

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

419

4207

0.91

0.33

4.1

3.9

—

(3013924) Clostridium tetani IgG Ab [Units/volume] in Serum

1.32

0.33

1.3

1.5

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

131

0.75

0.33

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.69

0.33

4.3

2.8

14.8

umol/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

332

3194

1.08

0.33

4.0

3.7

2.1

2.0

mu/l

0.70

308

2999

(3035320) C reactive protein [Mass/volume] in Body fluid

1.29

0.32

1.8

1.9

—

(21494755) Public health laboratory ask at order entry panel

195

0.80

0.32

1.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

575

1.11

0.31

2.1

1.9

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

209

1.19

0.31

3.4

3.0

5.3

5.1

pmol/l

0.38

190

(3028300) Cannabinoids [Presence] in Urine

497

0.88

0.30

1.4

1.7

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

162

1523

1.07

0.30

4.2

4.0

71.7

68.3

nmol/l

0.84

156

1445

(3014051) Protein [Presence] in Urine by Test strip

1.32

0.30

1.5

1.7

—

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

1.26

0.29

1.0

—

(40758558) Short blood count panel - Blood

162

1524

1.07

0.29

6.8

10.0

—

(3007164) IgA [Mass/volume] in Serum or Plasma

168

1738

0.93

0.29

1.7

1.5

1.4

g/l

0.42

867

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

106

0.74

0.29

1.5

1.3

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

1.24

0.29

1.0

1.1

—

(3032185) JC virus DNA [#/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.24

0.29

11.1

8.4

—

(3044889) 12 lead EKG panel

147

1379

1.07

0.29

2.3

2.1

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

297

2854

1.07

0.29

3.6

3.3

14.5

14.4

pmol/l

0.12

270

2583

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

202

1.18

0.28

2.0

2.4

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

192

0.82

0.28

1.7

1.4

0.2

g/l

0.04

185

(3008757) Leukocyte morphology finding [Identifier] in Blood

117

0.76

0.27

1.6

4.9

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

1.24

0.27

1.0

1.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.68

0.26

1.8

1.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

167

1.19

0.26

2.1

1.3

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

348

3506

0.94

0.25

15.9

15.2

139.2

139.3

mmol/l

0.47

339

3400

(3025159) Blasts/100 leukocytes in Blood

223

1.16

0.25

8.2

6.3

0.0

0.1

0.49

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

1.22

0.25

1.1

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

1.21

0.25

2.1

1.1

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

261

1.14

0.25

1.7

2.1

8.3

8.6

nmol/l

0.06

198

(40761535) Cells panel - Urine sediment

146

0.81

0.24

13.3

4.1

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

1.17

0.24

2.2

1.5

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

187

1.17

0.24

9.2

11.9

22.3

23.0

mmol/l

0.80

173

(3013336) Amino acids [Identifier] in Serum or Plasma

0.71

0.24

1.5

2.3

—

(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection

0.70

0.24

5.3

5.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

328

1.12

0.24

1.3

—

(3010813) Leukocytes [#/volume] in Blood

455

4537

0.91

0.23

17.1

17.7

7.2

7.1

e9/l

0.16

433

4276

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

282

1.13

0.22

1.6

1.5

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

1.24

0.22

1.8

4.1

212.4

324.4

ug/l

0.37

(3011397) Hemoglobin [Presence] in Urine by Test strip

105

983

1.07

0.22

4.1

3.5

—

(3045781) Inhibin B [Mass/volume] in Serum or Plasma

0.74

0.22

1.1

1.8

165.6

138.5

ng/l

—

(3011288) Drugs identified in Urine by Screen method

332

0.89

0.22

1.8

2.1

—

(3022096) Basophils/100 leukocytes in Blood

251

2414

1.05

0.22

7.8

10.7

0.6

0.22

245

2319

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

109

1023

1.07

0.22

6.4

11.3

23.3

23.6

mmol/l

0.60

102

996

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

217

1.15

0.22

1.1

—

33.8

—

(3025941) Bacteria identified in Stool by Culture

186

0.84

0.22

1.1

1.3

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

124

1.20

0.22

2.3

1.3

—

(3006665) Streptococcus pneumoniae Danish serotype 18C IgG Ab [Mass/volume] in Serum

1.21

0.22

1.6

1.9

6.1

1.4

mg/l

—

(3005665) Streptococcus pneumoniae Danish serotype 6B IgG Ab [Mass/volume] in Serum

1.21

0.22

1.6

1.9

3.5

3.0

mg/l

—

(36203821) Streptococcus pneumoniae Danish serotype 1 IgG Ab [Mass/volume] in Serum

1.21

0.22

1.6

1.9

0.9

1.1

mg/l

—

(36204005) Streptococcus pneumoniae Danish serotype 19F IgG Ab [Mass/volume] in Serum

1.21

0.22

1.6

1.9

1.1

5.8

mg/l

—

(36204286) Streptococcus pneumoniae Danish serotype 5 IgG Ab [Mass/volume] in Serum

1.21

0.22

1.6

1.9

2.0

1.4

mg/l

—

(3005260) Streptococcus pneumoniae Danish serotype 9V IgG Ab [Mass/volume] in Serum

1.21

0.22

1.6

1.9

0.4

1.1

mg/l

—

(3000899) Streptococcus pneumoniae Danish serotype 7F IgG Ab [Mass/volume] in Serum

1.21

0.22

1.6

1.9

1.1

mg/l

—

(3050099) BK virus DNA [#/volume] (viral load) in Specimen by NAA with probe detection

0.00

0.21

0.0

5.5

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(42528615) Etanercept [Mass/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

1.5

—

1.5

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.21

0.0

1.1

—

(3019779) Phenytoin [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

10.2

—

35.1

—

(1175553) Vedolizumab and Vedolizumab Ab panel [Mass/volume] - Serum or Plasma

0.00

0.21

0.0

18.4

—

(3043410) Blood group antigens tested for on Red Blood Cells

0.00

0.21

0.0

1.6

—

(36305075) Vedolizumab [Mass/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

18.5

—

26.9

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

181

1850

0.95

0.21

6.9

6.2

113.2

111.7

ml/min/173m2

0.31

119

1121

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

1.18

0.21

2.0

1.6

168.8

694.7

pmol/l

—

(21494814) CD8 cells/100 lymphocytes in Specimen

0.00

0.21

0.0

4.1

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3016228) CD19 cells/100 cells in Blood

0.00

0.21

0.0

4.2

—

14.3

—

(3000963) Hemoglobin [Mass/volume] in Blood

455

4534

0.91

0.21

17.3

18.1

132.9

131.7

g/l

1.08

448

4462

(3022229) Phosphate [Moles/volume] in Urine

1.23

0.21

2.9

3.3

21.9

20.1

mmol/l

0.17

(40765096) Chromosome analysis panel by Banding

0.00

0.20

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.20

0.0

1.1

—

(40763791) Oxygen content in Venous blood by calculation

0.00

0.20

0.0

12.2

—

13.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

162

1.16

0.20

3.1

2.2

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

132

0.82

0.20

1.5

1.2

—

(3006504) Eosinophils/100 leukocytes in Blood

255

2458

1.05

0.20

7.7

10.6

2.8

3.3

3.76

248

2352

(3036603) Volume of Urine

0.00

0.20

0.0

1.6

—

(3013707) Erythrocyte sedimentation rate by Westergren method

245

2481

0.95

0.20

4.1

4.6

6.3

7.3

mm/h

1.73

230

2310

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

409

1.10

0.19

11.9

9.7

59.9

50.1

ng/l

0.54

404

(3004119) Hemoglobin [Mass/volume] in Venous blood

236

0.87

0.19

7.5

18.3

124.5

125.3

g/l

0.06

231

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

1.19

0.19

1.0

1.1

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

1.14

0.19

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

145

1.16

0.18

1.1

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

136

1293

1.05

0.18

1.8

1.9

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

193

0.87

0.18

1.6

1.4

1.2

1.1

g/l

0.42

185

(3026361) Erythrocytes [#/volume] in Blood

455

4530

0.92

0.18

17.1

17.6

4.6

e12/l

0.98

434

4261

(3009466) Valproate [Moles/volume] in Serum or Plasma

1.20

0.18

5.3

4.7

475.1

439.7

umol/l

0.28

(3019060) Gas panel - Arterial blood

1.15

0.17

3.7

4.3

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

181

1841

0.96

0.17

2.8

2.9

1.1

mmol/l

0.36

170

1738

(3035941) MCH [Entitic mass]

455

4529

0.92

0.17

17.0

17.6

28.8

28.7

0.23

447

4455

(3002621) Streptococcal DNAse B [Units/volume] in Serum

1.14

0.17

1.3

1.1

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

349

3498

0.95

0.17

15.8

15.1

4.0

mmol/l

3.03

339

3372

(3000492) Spirometry study

250

1.11

0.17

1.6

1.4

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

528

1.07

0.17

18.6

22.1

1.1

mg/l

0.16

522

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.75

0.17

1.0

1.3

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

165

1.14

0.17

2.1

2.2

—

(3024731) MCV [Entitic volume]

455

4528

0.93

0.16

17.0

17.6

85.5

0.04

447

4451

(3023511) Choriogonadotropin [Units/volume] in Urine

222

0.89

0.16

1.5

1.4

—

(3006315) Basophils [#/volume] in Blood

260

2517

1.04

0.16

7.7

10.4

0.0

e9/l

0.27

212

2057

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

598

0.93

0.16

1.0

1.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.78

0.15

3.2

2.6

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

242

1.11

0.15

2.0

2.1

—

16.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

999

0.95

0.15

2.8

2.4

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

204

1967

1.04

0.15

3.6

43.3

48.7

ug/l

0.55

195

1868

(3007461) Platelets [#/volume] in Blood

455

4526

0.93

0.15

17.1

17.7

278.7

275.0

e9/l

0.53

434

4274

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

113

1075

1.05

0.15

2.5

3.5

2.5

2.7

mg/l

0.34

973

(40768443) Skin Pathology biopsy report

1.10

0.15

1.1

1.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

576

0.94

0.15

2.2

1.9

—

(3028707) Methadone [Presence] in Urine by Screen method

243

1.10

0.14

1.6

2.0

—

(3034770) Mitochondria Ab [Titer] in Serum

0.80

0.14

2.4

2.3

—

(3011841) English Walnut IgE Ab [Units/volume] in Serum

1.19

0.14

1.3

16.9

15.1

u/ml

0.04

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

675

0.94

0.14

1.7

3.2

57.4

55.6

u/l

0.12

629

(3027135) IgG subclass 1 [Mass/volume] in Serum

0.83

0.14

1.4

1.3

6.4

5.9

g/l

—

(3028192) IgG subclass 2 [Mass/volume] in Serum

0.83

0.14

1.4

1.3

2.3

2.0

g/l

—

(3024139) IgG subclass 3 [Mass/volume] in Serum

0.83

0.14

1.4

1.3

0.2

0.4

g/l

—

(3021589) Normoblasts [#/volume] in Blood

248

2405

1.04

0.13

9.3

12.2

0.0

e9/l

0.56

182

1793

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

361

3525

1.04

0.13

7.5

9.6

25.5

24.9

u/l

0.10

347

3396

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

213

2060

1.04

0.13

2.3

2.2

5.2

5.3

mmol/l

0.69

191

1870

(3001604) Monocytes [#/volume] in Blood

259

2514

1.04

0.13

7.7

10.4

0.6

e9/l

0.67

212

2056

(3042936) Bacteria identified in Isolate by Culture

422

0.93

0.13

2.2

1.9

—

(3035933) Granulocytes/100 leukocytes in Blood

126

0.86

0.13

1.1

1.4

—

(3003396) Base excess in Arterial blood by calculation

226

1.10

0.13

10.2

16.7

-1.4

-0.0

mmol/l

0.94

181

(3018010) Neutrophils/100 leukocytes in Blood

260

2526

1.03

0.13

7.4

10.2

46.5

47.9

0.98

253

2432

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

150

1.12

0.12

10.0

21.0

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

236

1.09

0.12

1.7

1.8

—

(44813793)

1.18

0.12

1.0

1.1

—

(3019150) Specific gravity of Urine by Refractometry

762

0.95

0.12

3.7

3.2

1.0

kg/l

0.01

146

(3003694) ABO and Rh group [Type] in Blood

123

1251

0.96

0.12

1.6

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

450

0.94

0.12

1.2

1.3

1.5

3.3

u/ml

0.63

304

(3002385) Erythrocyte distribution width [Ratio]

392

3906

0.96

0.11

16.6

17.4

13.3

13.2

1.18

384

3839

(42528717) Cashew nut recombinant (rAna o) 3 IgE Ab [Units/volume] in Serum

1.16

0.11

1.3

1.2

7.9

7.1

u/ml

0.05

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

196

0.90

0.11

1.2

1.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

199

1.10

0.11

2.1

2.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

547

1.05

0.11

2.8

2.2

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

124

0.87

0.11

1.7

1.6

—

(3033658) Prothrombin time (PT) actual/Normal

108

1098

0.96

0.10

6.6

10.5

83.9

84.2

0.04

108

1089

(3047007) Chlamydophila sp Ab [Presence] in Serum

200

1.09

0.10

1.2

1.1

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

1.10

0.09

2.4

1.9

—

(3018405) Lactate [Moles/volume] in Arterial blood

1.07

0.09

5.4

4.3

2.0

1.7

mmol/l

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

1.05

0.09

1.0

1.1

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

356

1.06

0.09

2.2

2.3

6.6

5.5

u/l

0.35

217

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

1.13

0.08

2.2

1.4

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

415

0.95

0.08

1.2

0.4

4.5

u/ml

4.71

140

(3026389) Candida sp identified in Specimen by Organism specific culture

1.08

0.08

1.0

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

173

0.91

0.08

1.3

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

1.06

0.08

2.2

1.8

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

705

0.96

0.08

2.3

2.2

—

(3002030) Lymphocytes/100 leukocytes in Blood

264

2578

1.02

0.08

7.6

10.3

37.9

36.5

1.06

257

2480

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

1.08

0.08

1.0

1.3

—

(3003752) BK virus DNA [Units/volume] (viral load) in Urine by NAA with probe detection

1.03

0.08

8.9

6.8

—

(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection

1.03

0.08

7.3

6.7

—

(3003740) Influenza virus B Ag [Presence] in Specimen

172

0.92

0.08

1.3

—

(4198724)

0.84

0.07

1.3

1.5

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

329

1.05

0.07

2.3

7.3

6.4

iu/l

0.15

211

(3052851) Hemolysis interference index of Serum or Plasma

155

1.09

0.07

2.9

3.9

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

161

0.92

0.07

1.1

3.2

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

452

0.96

0.07

8.5

17.6

1.6

1.3

mmol/l

0.84

407

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

136

1.09

0.07

1.5

1.3

—

(44790049)

165

1.08

0.07

1.9

2.3

—

(44790048)

165

1.08

0.07

1.9

2.3

—

(3022621) pH of Urine by Test strip

165

1.08

0.07

2.2

1.9

—

(44790047)

165

1.08

0.07

1.9

2.3

—

(44806118)

165

1.08

0.07

1.9

2.3

—

(40761536) Microorganisms panel - Urine sediment

262

1.06

0.07

3.9

4.1

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.89

0.07

1.8

1.7

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.86

0.07

2.3

1.7

—

(3023520) Reticulocytes [#/volume] in Blood

457

1.04

0.06

3.1

5.9

58.4

62.2

e9/l

0.24

288

(4062490)

0.84

0.06

1.4

1.3

—

(3000494) Fungus identified in Specimen by Culture

350

1.05

0.06

2.5

1.9

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

624

1.03

0.06

2.8

6.3

1.4

2.2

mg/l

1.05

450

(3014765) Yersinia sp identified in Stool by Organism specific culture

127

1.09

0.06

1.0

1.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

416

4129

0.97

0.06

14.7

16.9

39.4

38.9

1.74

374

3711

(3000991) Gas panel - Venous blood

101

978

1.03

0.06

9.3

13.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

439

1.04

0.06

2.7

2.3

56.4

45.4

ng/l

0.09

163

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

118

1.09

0.05

3.7

5.0

23.8

24.0

umol/l

0.04

118

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

103

1036

0.98

0.05

3.8

3.5

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

352

1.04

0.05

1.2

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

157

1.07

0.05

1.2

1.4

144.7

259.1

miu/ml

—

(40761511) CBC panel - Blood by Automated count

396

3894

1.02

0.05

9.7

8.8

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

1.10

0.05

5.8

4.3

47.0

48.5

0.14

(3019198) Lymphocytes [#/volume] in Blood

260

2587

0.99

0.04

7.7

10.3

2.7

2.5

e9/l

1.37

218

2191

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

218

0.95

0.04

2.9

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

178

0.94

0.04

2.3

2.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

137

1337

1.02

0.04

3.8

4.7

—

(42529406) Shigella sp [Presence] in Stool by Culture

129

1.07

0.04

1.0

1.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

774

0.98

0.03

5.5

5.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

650

1.02

0.03

2.0

1.8

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

277

1.04

0.03

1.3

1.4

551.3

26693694.3

pmol/l

0.50

251

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

445

0.97

0.03

2.9

2.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

445

0.97

0.03

3.0

2.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

730

1.02

0.02

3.7

3.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

732

0.98

0.02

1.9

1.6

102.0

97.8

pmol/l

0.28

384

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

209

1.04

0.02

1.1

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

111

1.07

0.02

1.9

1.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

180

1.04

0.02

1.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

105

1047

0.99

0.02

2.5

2.1

—

(36660697) Celiac disease serology panel - Serum

801

1.01

0.02

1.3

1.2

—

(3024354) Oxygen [Partial pressure] in Venous blood

107

1048

1.01

0.01

7.5

12.1

5.2

5.3

kpa

0.12

102

1025

(3021879) Hepatitis B virus core Ab [Presence] in Serum

274

0.97

0.01

2.0

1.4

—

(1761868) Lipid panel - Serum or Plasma

575

1.02

0.01

2.1

1.8

—

(3021901) Oxygen saturation in Capillary blood

112

1.06

0.01

7.8

9.5

—

(3035637) Corticotropin [Mass/volume] in Plasma

234

0.97

0.01

1.8

—

(3029937) Albumin [Presence] in Urine by Test strip

764

1.01

0.00

4.4

3.9

0.0

estimate

0.00

266

(3050129) First trimester maternal screen panel - Serum or Plasma

181

0.98

0.00

1.6

1.4

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

104

1.05

0.00

1.2

1.6

11.4

5.0

ug/l

0.48

(3030905) Polymorphonuclear cells [#/volume] in Blood

1.03

0.00

6.1

3.7

3.4

3.1

e9/l

—

(3013512) EKG study

387

1.00

0.00

2.7

2.6

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

142

0.97

0.00

1.8

1.6

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

419

0.99

0.00

1.1

1.2

0.7

0.9

u/ml

0.14

310

(3003888) Timothy IgE Ab [Units/volume] in Serum

427

0.99

0.00

1.1

1.2

4.7

5.6

u/ml

0.14

329

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

348

0.99

0.00

1.1

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

123

1.05

0.00

1.0

1.1

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

167

1.01

0.00

12.9

21.1

0.7

0.8

0.30

167

(3002032) Base excess in Venous blood by calculation

109

1080

1.00

0.00

7.7

12.3

0.6

1.0

mmol/l

0.59

836

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

1.04

0.00

1.7

1.8

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

109

1.00

0.00

14.5

6.1

36.4

30.4

u/ml

0.10

104

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

131

0.98

0.00

2.1

1.7

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

109

1082

0.99

0.00

7.6

12.2

5.7

kpa

0.54

104

1058

(3014007) Fractional oxyhemoglobin in Arterial blood

165

1.02

0.00

13.2

21.3

94.4

95.7

0.17

165

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

350

0.99

0.00

1.4

1.3

218.4

143.9

iu/ml

—

107

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

6.1

—

1.9

—

(3041365) Herpes simplex virus IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(40761995) Spermatozoa Progressive [#/volume] in Semen

0.00

0.0

1.3

—

(3012787) Ethosuximide [Moles/volume] in Serum or Plasma

0.00

0.0

1.7

—

403.3

—

(3013290) Carbon dioxide [Partial pressure] in Blood

1.00

0.00

8.0

10.5

5.2

4.9

kpa

—

(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen

0.00

0.0

2.7

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.96

0.00

3.4

2.6

—

(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen

0.00

0.0

5.2

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

8.1

—

(3027315) Oxygen [Partial pressure] in Blood

1.00

0.00

8.1

9.9

9.5

9.1

kpa

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

1.3

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.91

0.00

1.2

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.90

0.00

4.1

5.1

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.86

0.00

1.0

1.4

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3007463) Buprenorphine [Presence] in Urine

0.00

0.0

2.6

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

1.0

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.0

1.3

—

(40760409) HLA-A [Type] by High resolution

0.00

0.0

1.0

—

(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay

0.00

0.0

1.2

—

(3040562) Leukocytes [#/volume] in Peritoneal dialysis fluid by Manual count

0.00

0.0

2.6

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

0.89

0.00

1.0

1.2

—

0.2

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.91

0.00

4.0

4.9

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.99

0.00

2.0

1.8

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.91

0.00

1.4

1.2

—

(3023365) Varicella zoster virus Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3006441) Cardiolipin IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.5

—

(3013862) HLA-DP [Type]

0.00

0.0

1.0

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.97

0.00

1.0

1.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

1.3

—

(40757373) Influenza virus identified in Isolate

0.00

0.0

1.4

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.93

0.00

1.0

1.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

3.3

—

14.3

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.96

0.00

1.4

1.2

63.8

75.8

—

(36305790) Ustekinumab [Mass/volume] in Serum or Plasma by Immunoassay

0.00

0.0

5.9

—

3.9

—

(40763590) HLA-DQ beta [Type]

0.00

0.0

1.0

—

(3015822) Parvovirus B19 DNA [Presence] in Serum by NAA with probe detection

0.00

0.0

1.2

—

(40760410) HLA-B [Type] by High resolution

0.00

0.0

1.0

—

(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

4.0

—

(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(3020650) Glucose [Presence] in Urine

0.00

0.0

1.7

—

(4146454)

0.00

0.0

3.9

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

1.3

—

(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum

0.00

0.0

1.0

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.7

—

(3016135) IgD [Mass/volume] in Serum

0.00

0.0

1.0

—

25.6

—

(3033888) Pepsinogen I [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

75.1

—

(3010254) Herpes simplex virus identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(40760083) Phosphate/Creatinine [Ratio] in Urine

0.00

0.0

5.6

—

(3035929) Mycoplasma pneumoniae Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.91

0.00

2.1

2.8

—

(46236302) HLA-C [Type] by High resolution typing

0.00

0.0

1.0

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.89

0.00

1.0

1.2

—

33.5

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.96

0.00

1.4

1.2

—

(42868647) JC virus Ab [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.95

0.00

1.6

1.5

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.2

—

980.4

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3014591) Smooth Alder IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3052592) Norovirus Ag [Presence] in Stool

0.00

0.0

1.4

—

(3034037) Hematocrit [Volume Fraction] of Mixed venous blood

0.00

0.0

17.7

—

(3025378) Microscopic observation [Identifier] in Cervix by Cyto stain

0.00

0.0

1.2

—

(3036035) von Willebrand factor (vWf) Ag actual/normal in Platelet poor plasma by Immunoassay

0.95

-0.00

1.4

2.0

82.6

124.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV and mortality.

Females

Parameter	HR [95% CI]	p-value
P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV	1.511 [1.16, 1.97]	0.002
Birth year	0.998 [0.99, 1.01]	0.664

During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 18172 females with P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV died.

Males

Parameter	HR [95% CI]	p-value
P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV	1.458 [1.19, 1.79]	< 0.001
Birth year	0.991 [0.98, 1.0]	0.065

During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 21554 males with P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV died.

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV.

N-year risk	Females	Males
1	0.105%	0.363%
5	0.922%	1.99%
10	2.39%	4.812%
15	4.726%	9.086%
20	8.271%	14.988%

Relationships between endpoints

↥

Index endpoint: P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV – Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints