No definition available.
Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
506 |
4. Check minimum number of eventsNone |
506 |
5. Include endpoints |
506 |
6. Filter based on genotype QC (FinnGen only) |
506 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- P
- Name in latin
- Fetus et neonatus factoribus maternis atque complicationibus graviditatis, laborum et partus affectus
Similar endpoints
↥List of similar endpoints to
Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
- Fetus and newborn affected by maternal complications of pregnancy
- Fetus and newborn affected by maternal conditions that may be unrelated to present pregnancy
- Fetus and newborn affected by other complications of labour and delivery
- Fetus and newborn affected by complications of placenta, cord and membranes
- Fetus and newborn affected by noxious influences transmitted via placenta or breast milk
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 43198 | 19780 | 23410 |
| Only index persons | 16855 | 7854 | 9001 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.61 | 0.57 | 0.65 |
| Only index persons | 0.32 | 0.29 | 0.34 |
| Median age at first event (years) | |||
| Whole population | 0.01 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 506 | 277 | 229 |
| Unadjusted period prevalence (%) | 0.10 | 0.09 | 0.10 |
| Median age at first event (years) | 0.00 | 0.00 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 443
- Matched controls
- 4344
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P07.3
ICD-10 Finland
Other preterm infants
24.5
122.5
183
121
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
+∞
98.0
91
*
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
+∞
96.9
90
*
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
+∞
82.4
77
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
13.9
78.2
145
147
P03.4
ICD-10 Finland
Fetus and newborn affected by caesarean delivery
+∞
41.0
39
*
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
23.2
28.5
41
19
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
13.4
26.7
47
38
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
8.5
25.3
57
74
P00.8
ICD-10 Finland
Fetus and newborn affected by other maternal conditions
+∞
22.9
22
*
P02.1
ICD-10 Finland
Fetus and newborn affected by other forms of placental separation and haemorrhage
+∞
20.8
20
*
WX722
NOMESCO Finland
PEEP
6.3
20.7
57
99
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
9.4
20.6
43
49
P39.9
ICD-10 Finland
Infection specific to the perinatal period, unspecified
12.4
18.4
33
28
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
4.1
17.5
73
200
P05.1
ICD-10 Finland
Small for gestational age
10.5
17.0
33
33
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
6.2
16.4
45
78
P05.0
ICD-10 Finland
Light for gestational age
15.8
16.2
26
17
P07.1
ICD-10 Finland
Other low birth weight
30.8
16.1
21
7
P07.2
ICD-10 Finland
Extreme immaturity
17.9
13.8
21
12
P02.7
ICD-10 Finland
Fetus and newborn affected by chorioamnionitis
+∞
13.5
13
*
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
22.9
12.9
18
8
P03.0
ICD-10 Finland
Fetus and newborn affected by breech delivery and extraction
+∞
12.5
12
*
P00.2
ICD-10 Finland
Fetus and newborn affected by maternal infectious and parasitic diseases
+∞
12.5
12
*
P03.3
ICD-10 Finland
Fetus and newborn affected by delivery by vacuum extractor [ventouse]
+∞
12.5
12
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
9.9
12.2
24
25
P04.1
ICD-10 Finland
Fetus and newborn affected by other maternal medication
+∞
11.4
11
*
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
6.5
11.4
29
46
602
Kela drug reimbursment
Children's severe malnutrition
3.7
11.3
51
149
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
16.9
9.8
15
9
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
11.5
9.5
17
15
H35.1
ICD-10 Finland
Retinopathy of prematurity
17.7
9.4
14
8
P04.4
ICD-10 Finland
Fetus and newborn affected by maternal use of drugs of addiction
+∞
9.3
9
*
P03.1
ICD-10 Finland
Fetus and newborn affected by other malpresentation, malposition and disproportion during labour and delivery
+∞
9.3
9
*
A11JC
ATC
Vitamins, other combinations
14.1
8.6
14
10
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
8.5
92
459
P04.2
ICD-10 Finland
Fetus and newborn affected by maternal use of tobacco
+∞
8.3
8
*
P70.1
ICD-10 Finland
Syndrome of infant of a diabetic mother
8.6
8.3
17
20
WX882
NOMESCO Finland
High dependency care
2.2
8.0
82
400
P22.8
ICD-10 Finland
Other respiratory distress of newborn
8.5
7.8
16
19
R4110
NOMESCO Finland
Physiotherapy
1.9
7.5
129
769
P22.9
ICD-10 Finland
Respiratory distress of newborn, unspecified
5.1
7.4
22
44
P01.11
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes more than 7 days before delivery
+∞
7.3
7
*
P21.0
ICD-10 Finland
Severe birth asphyxia
11.0
6.2
11
10
Z2446
NOMESCO Finland
Social worker
1.9
6.2
107
636
P02.6
ICD-10 Finland
Fetus and newborn affected by other and unspecified conditions of umbilical cord
+∞
6.2
6
*
RK312
NOMESCO Finland
NA
7.0
6.2
14
20
P36.90
ICD-10 Finland
Suspected bacterial sepsis of newborn
4.5
6.1
20
45
Mortality – FinRegistry
↥Association
Association between endpoint P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV | 1.511 [1.16, 1.97] | 0.002 |
| Birth year | 0.998 [0.99, 1.01] | 0.664 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 18172 females with P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV | 1.458 [1.19, 1.79] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.065 |
During the follow-up period (1.1.1998 — 31.12.2019), 107 out of 21554 males with P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV died.
Mortality risk
Mortality risk for people of age
years, who have P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.105% | 0.363% |
| 5 | 0.922% | 1.99% |
| 10 | 2.39% | 4.812% |
| 15 | 4.726% | 9.086% |
| 20 | 8.271% | 14.988% |
Relationships between endpoints
↥Index endpoint: P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV – Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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