Fetus and newborn affected by other complications of labour and delivery

P16_FET_NEWB_OTH_COMPLICATIO_LABOUR_DELIV

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P03
  • Cause of death: ICD-10 P03

2 out of 7 registries used, show all original rules.

83

4. Check minimum number of events

None

83

5. Include endpoints

None

83

6. Filter based on genotype QC (FinnGen only)

83

Control definitions (FinnGen only)

Control exclude
P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P0[0-4]
Name in latin
Fetus et neonatus aliis complicationibus laborum et partus affectus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12078 5291 6784
Only index persons 3261 1433 1828
Unadjusted period prevalence (%)
Whole population 0.17 0.15 0.19
Only index persons 0.06 0.05 0.07
Median age at first event (years)
Whole population 0.01 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 83 51 32
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
76
Matched controls
761
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P03.4
ICD-10 Finland
Fetus and newborn affected by caesarean delivery
+∞
45.4
39
*
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
24.7
16.4
23
13
P03.0
ICD-10 Finland
Fetus and newborn affected by breech delivery and extraction
+∞
12.9
12
*
P03.3
ICD-10 Finland
Fetus and newborn affected by delivery by vacuum extractor [ventouse]
+∞
12.9
12
*
P03.1
ICD-10 Finland
Fetus and newborn affected by other malpresentation, malposition and disproportion during labour and delivery
+∞
9.6
9
*
P07.3
ICD-10 Finland
Other preterm infants
13.2
9.3
16
15
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
+∞
8.5
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
9
7.06
2.91
6.8
3.3
—
—
—
0
0
11
37
3.27
2.80
4.5
7.2
0.2
0.0
%
—
5
15
11
39
3.09
2.58
4.5
7.1
2.0
0.2
%
—
5
17
7
23
3.22
1.84
19.1
4.2
—
—
—
0
0
19
119
1.77
1.24
3.5
5.1
1.1
1.1
inr
—
8
40
5
20
2.59
1.16
2.2
1.1
—
—
—
0
0
24
167
1.61
1.07
2.6
3.2
—
—
—
0
0
21
142
1.64
1.05
4.0
5.1
—
—
—
0
0
0
28
0.00
1.00
0.0
2.1
—
—
—
0
0
41
329
1.48
0.95
5.3
7.0
5.7
5.9
mmol/l
0.24
35
294
23
307
0.65
0.94
1.9
1.8
0.4
3.4
u/ml
—
6
62
12
73
1.75
0.86
2.4
2.3
—
—
—
0
0
22
292
0.66
0.86
1.9
1.7
1.6
1.6
g/l
0.00
12
150
6
32
1.94
0.83
2.3
1.8
—
—
—
0
0
15
100
1.61
0.79
1.6
1.7
—
—
—
0
0
17
118
1.55
0.76
2.3
1.6
—
—
—
0
0
7
118
0.55
0.75
2.1
1.6
—
—
—
0
0
37
302
1.40
0.74
4.5
3.1
35.1
35.7
mmol/mol
0.14
37
278
5
28
1.83
0.67
11.4
2.6
1.3
1.2
mmol/l
—
5
23
0
21
0.00
0.61
0.0
5.1
—
—
—
0
0
0
21
0.00
0.61
0.0
1.9
—
2.5
—
0
6
0
22
0.00
0.60
0.0
2.8
—
—
—
0
0
13
178
0.68
0.57
1.8
1.8
—
—
—
0
0
19
242
0.72
0.56
3.2
8.3
—
—
—
0
0
12
83
1.52
0.55
3.2
2.8
164.6
19.7
ng/l
—
7
32
19
145
1.40
0.54
7.6
4.8
8.1
8.4
mmol/l
0.11
19
134
61
653
0.74
0.49
12.6
10.9
18.0
23.7
mg/l
0.81
48
435
44
387
1.29
0.48
7.6
4.4
—
—
—
0
0
20
161
1.32
0.41
3.3
2.5
—
—
—
0
0
8
60
1.36
0.41
5.1
4.7
64.3
59.5
e9/l
—
8
45
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
294.6
—
0
12
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
36
404
0.80
0.39
8.5
10.7
0.0
0.0
e9/l
0.00
31
308
9
70
1.32
0.38
22.7
5.1
279.4
299.9
umol/l
—
9
65
28
239
1.25
0.37
5.8
6.0
20.9
41.3
e6/l
0.58
20
168
19
229
0.78
0.37
1.6
2.2
—
—
—
0
0
27
230
1.25
0.37
1.6
1.7
—
—
—
0
0
12
91
1.37
0.35
3.7
2.5
916.0
4264.8
u/l
—
5
31
7
52
1.37
0.32
5.0
13.7
105.4
106.2
mmol/l
—
7
52
63
659
0.81
0.29
8.4
13.9
39.0
39.1
%
0.05
53
585
11
137
0.77
0.27
9.9
11.2
6.0
5.8
kpa
0.47
11
132
13
158
0.79
0.27
2.9
3.6
—
—
—
0
0
9
74
1.24
0.26
1.6
1.2
14.4
19.3
nmol/l
—
9
59
9
76
1.20
0.25
4.6
3.6
2.6
2.7
g/l
—
9
71
11
88
1.28
0.23
5.7
7.4
1.6
1.2
%
0.67
11
83
17
145
1.21
0.22
4.9
4.4
0.0
0.0
estimate
—
7
57
13
154
0.81
0.21
10.9
13.5
24.1
24.7
mmol/l
0.69
13
154
0
10
0.00
0.21
0.0
2.1
—
1.1
—
0
10
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
9.3
—
10.7
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.3
—
—
—
0
0
11
90
1.25
0.20
1.3
2.1
—
—
—
0
0
33
302
1.15
0.20
5.5
9.7
—
—
—
0
0
6
52
1.16
0.19
6.8
3.1
—
—
—
0
0
23
207
1.15
0.17
1.8
2.0
—
—
—
0
0
8
72
1.12
0.16
1.3
2.3
—
—
—
0
0
11
129
0.83
0.16
1.2
1.3
—
—
—
0
0
9
82
1.11
0.15
1.2
2.2
—
—
—
0
0
11
128
0.84
0.15
10.5
10.4
—
—
—
0
0
9
108
0.81
0.14
2.1
1.8
1.5
1.2
mmol/l
—
9
101
29
269
1.12
0.13
4.3
4.2
0.0
0.0
estimate
—
7
56
22
238
0.89
0.12
2.4
2.1
—
—
—
0
0
10
114
0.86
0.10
7.0
3.8
7.4
7.4
ph
—
5
21
5
46
1.09
0.10
1.4
2.2
—
—
—
0
0
9
104
0.85
0.06
3.9
1.7
—
—
—
0
0
15
138
1.10
0.06
5.5
3.8
—
—
—
0
0
10
90
1.12
0.05
1.2
2.1
—
—
—
0
0
10
90
1.12
0.05
1.2
2.1
—
—
—
0
0
26
269
0.95
0.03
5.8
5.8
0.0
0.0
estimate
—
7
56
19
183
1.05
0.01
5.4
4.7
—
—
—
0
0
12
114
1.06
0.00
2.3
2.6
55.8
62.5
u/l
0.18
12
101
16
154
1.05
0.00
1.4
1.7
—
—
—
0
0
12
123
0.97
0.00
2.1
1.4
94.3
94.8
pmol/l
—
7
65
27
269
1.00
0.00
4.6
4.1
0.0
0.0
estimate
—
5
56
15
152
0.98
0.00
1.5
1.8
—
—
—
0
0
65
647
1.01
0.00
11.6
8.6
—
—
—
0
0
14
139
1.01
0.00
12.5
9.2
24.0
23.9
mmol/l
0.04
14
139
14
138
1.01
0.00
13.1
10.4
—
—
—
0
0
11
107
1.03
0.00
2.1
3.6
—
—
—
0
0
21
211
0.99
0.00
3.0
3.8
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.87
0.00
1.5
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
5
55
0.90
0.00
1.0
2.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
4.0
—
0
5
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
9
90
1.00
0.00
1.2
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
22.8
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
4.0
—
4.5
—
0
7
0
5
0.00
0.00
0.0
2.4
—
30.4
—
0
5
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_FET_NEWB_OTH_COMPLICATIO_LABOUR_DELIV and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_OTH_COMPLICATIO_LABOUR_DELIV.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FET_NEWB_OTH_COMPLICATIO_LABOUR_DELIV – Fetus and newborn affected by other complications of labour and delivery

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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