Fetus and newborn affected by complications of placenta, cord and membranes

P16_FET_NEWB_COMPLICATIO_PLACEN_CORD_MEMBRANES

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P02 Cause of death: ICD-10 — P02 2 out of 7 registries used, show all original rules.	65
4. Check minimum number of events None	65
5. Include endpoints None	65
6. Filter based on genotype QC (FinnGen only)	65

Control definitions (FinnGen only)

Control exclude: P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P0[0-4]
Name in latin: Fetus et neonatus complicationibus placentae, funiculi umbilicalis et membranarum fetalium affectus

NAME	P16_FET_NEWB_COMPLICATIO_PLACEN_CORD_MEMBRANES
CONTROL_EXCLUDE	P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P02
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P02
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Fetus and newborn affected by complications of placenta, cord and membranes based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	3567	1640	1924
Only index persons	1327	609	718
Unadjusted period prevalence (%)
Whole population	0.05	0.05	0.05
Only index persons	0.03	0.02	0.03
Median age at first event (years)
Whole population	0.03	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	65	35	30
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
56: Matched controls
558

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P02.1

ICD-10 Finland

Fetus and newborn affected by other forms of placental separation and haemorrhage

+∞

22.4

Z87.6

ICD-10 Finland

Personal history of certain conditions arising in the perinatal period

19.3

14.2

P02.7

ICD-10 Finland

Fetus and newborn affected by chorioamnionitis

+∞

14.1

P07.3

ICD-10 Finland

Other preterm infants

14.1

10.5

WX722

NOMESCO Finland

PEEP

10.5

6.4

P02.6

ICD-10 Finland

Fetus and newborn affected by other and unspecified conditions of umbilical cord

+∞

6.4

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3000492) Spirometry study

3.65

2.26

1.6

1.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

5.31

2.11

1.8

1.4

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

4.07

1.75

1.8

2.3

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.89

1.63

2.1

1.6

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.89

1.63

2.1

1.6

—

(3005322) IgE [Units/volume] in Serum or Plasma

2.25

1.62

1.2

1.4

198.7

536.4

u/ml

0.42

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

3.52

1.55

1.8

2.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

139

1.88

1.49

2.2

3.6

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.32

1.40

1.9

1.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.10

1.38

1.4

2.1

—

(3026008) Bacteria identified in Urine by Culture

117

1.88

1.38

2.6

2.5

—

(3022313) Gas panel - Capillary blood

110

1.88

1.33

23.5

14.4

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.92

1.31

1.8

2.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

264

1.71

1.27

1.9

2.0

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

2.44

1.21

4.3

2.7

5.4

5.1

pmol/l

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

0.00

1.20

0.0

2.5

—

78.9

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

2.62

1.17

2.4

1.9

—

(44790047)

2.62

1.17

1.8

2.1

—

(44790049)

2.62

1.17

1.8

2.1

—

(44806118)

2.62

1.17

1.8

2.1

—

(44790048)

2.62

1.17

1.8

2.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

300

1.64

1.11

4.4

4.7

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.49

1.11

1.8

2.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

2.11

1.09

1.6

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.37

1.05

1.8

2.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

110

1.74

1.04

2.6

3.2

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

119

1.71

1.02

26.3

15.2

4.9

kpa

0.11

113

(3019150) Specific gravity of Urine by Refractometry

111

1.72

1.00

2.1

3.2

1.0

kg/l

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.99

0.0

2.6

—

(3044640) Blood type and Crossmatch panel - Blood

129

1.67

0.98

2.4

3.2

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.98

0.0

2.6

—

(4010399)

2.10

0.89

1.5

—

(3003694) ABO and Rh group [Type] in Blood

168

1.57

0.88

1.4

1.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

134

1.59

0.84

3.3

3.5

—

(40758558) Short blood count panel - Blood

207

1.52

0.83

6.3

7.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

509

1.72

0.82

18.3

15.4

39.8

38.8

0.92

449

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

0.00

0.81

0.0

4.5

—

3.4

—

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

0.00

0.81

0.0

4.5

—

1121.3

—

(3006245) CD3-CD19+ cells/100 cells in Blood

0.00

0.81

0.0

3.7

—

19.8

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

0.00

0.81

0.0

4.5

—

4.6

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.00

0.81

0.0

4.3

—

330.6

—

(3052851) Hemolysis interference index of Serum or Plasma

2.27

0.78

2.0

1.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.74

0.78

3.9

2.2

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

1.89

0.75

2.1

1.5

286.1

329.8

mu/l

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

2.08

0.74

1.2

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

1.84

0.74

4.9

7.5

135.7

161.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.84

0.74

4.7

2.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.84

0.74

4.7

2.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

175

1.49

0.72

2.0

—

(3015736) pH of Urine

166

1.49

0.72

3.1

4.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

1.66

0.71

1.2

1.3

109.4

95.9

pmol/l

—

(3028626) Oxygen [Partial pressure] in Capillary blood

113

1.55

0.69

28.6

14.9

9.9

kpa

0.05

107

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

178

1.45

0.66

3.7

4.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

178

1.45

0.66

4.2

5.5

—

(3000494) Fungus identified in Specimen by Culture

1.72

0.65

1.6

1.3

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.78

0.65

1.4

1.8

—

(3018095) Leukocytes [#/volume] in Urine

197

1.44

0.65

4.8

6.4

6.1

48.3

e6/l

1.36

133

(3028707) Methadone [Presence] in Urine by Screen method

1.72

0.62

1.2

1.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.61

0.62

1.0

1.4

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

0.61

0.0

3.5

—

24.1

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.61

0.0

3.4

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.61

0.0

2.1

—

(3022145) Colonoscopy Study observation

0.00

0.61

0.0

1.5

—

(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood

0.00

0.61

0.0

3.3

—

724.5

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.61

0.0

3.4

—

(1175426) CD3 cells/100 lymphocytes in Blood

0.00

0.61

0.0

3.3

—

66.0

—

(3011412) CD3 cells [#/volume] in Blood

0.00

0.61

0.0

3.3

—

2.2

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.61

0.0

5.0

—

(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood

0.00

0.61

0.0

3.3

—

0.2

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.60

0.0

4.8

—

(3022621) pH of Urine by Test strip

0.00

0.60

0.0

1.8

—

(3012494) Peanut IgE Ab [Units/volume] in Serum

0.00

0.60

0.0

1.2

—

1.6

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

0.00

0.60

0.0

6.3

—

227.7

—

(3042936) Bacteria identified in Isolate by Culture

1.79

0.59

2.3

2.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

1.79

0.59

3.7

4.1

15.8

22.3

mg/mmol

—

(42870588) Differential panel, method unspecified - Blood

238

1.39

0.59

4.5

9.8

—

(3000060) B lymphocytes [#/volume] in Blood

0.00

0.59

0.0

3.3

—

495.3

—

(3012516) Albumin [Mass/volume] in Urine

1.73

0.58

3.8

3.6

157.8

130.3

mg/l

—

(3032080) INR in Blood by Coagulation assay

0.57

1.5

4.1

—

1.2

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

341

1.36

0.52

6.4

9.9

3.0

3.4

e9/l

0.96

283

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

424

1.39

0.51

4.0

3.5

1.9

2.1

mu/l

0.82

391

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.55

0.49

4.0

1.8

—

(36660697) Celiac disease serology panel - Serum

125

0.68

0.49

1.3

1.1

—

(3044889) 12 lead EKG panel

178

1.36

0.47

1.8

2.0

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

276

1.31

0.45

2.2

2.3

5.1

5.4

mmol/l

0.99

248

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

1.41

0.43

3.1

4.9

22.0

21.4

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

134

1.36

0.42

1.6

2.9

2.6

mg/l

0.17

116

(3035637) Corticotropin [Mass/volume] in Plasma

1.56

0.42

1.8

2.1

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.42

0.0

1.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.41

0.0

1.1

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.41

0.0

1.9

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.41

0.0

1.1

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.41

0.0

4.9

—

(3045414) Leukocytes [Presence] in Urine

0.00

0.40

0.0

1.9

—

(3030467) Casts [#/volume] in Urine by Automated count

156

1.31

0.36

3.9

5.2

0.2

0.3

e6/l

0.12

113

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

128

1.33

0.36

3.1

2.5

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

206

1.26

0.33

2.2

4.3

19.2

25.5

u/l

1.32

198

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.42

0.33

5.7

8.7

81.4

85.4

—

(40761511) CBC panel - Blood by Automated count

499

1.34

0.33

10.0

7.8

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.36

0.33

2.2

3.7

—

(36304419) Bacteria [Presence] in Urine

159

1.28

0.31

3.8

5.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.32

0.29

1.8

1.9

—

(3007164) IgA [Mass/volume] in Serum or Plasma

252

0.81

0.28

1.4

1.6

1.4

g/l

—

110

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

1.26

0.28

3.4

2.9

960.3

702.0

u/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.23

0.26

1.8

1.9

—

(3012544) pH of Venous blood

115

1.28

0.26

4.6

11.7

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.75

0.24

2.3

2.0

—

(42870560) Thyrotropin [Units/volume] in Cord blood

1.27

0.23

1.0

12.1

7.2

mu/l

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.27

0.23

1.2

—

(3021589) Normoblasts [#/volume] in Blood

312

1.19

0.23

6.9

9.6

0.0

e9/l

0.00

235

(3013826) Glucose [Moles/volume] in Serum or Plasma

253

1.19

0.22

7.5

8.8

6.6

5.8

mmol/l

0.62

239

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.21

0.0

3.0

—

2.5

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.21

0.0

3.0

—

45.1

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.21

0.0

2.3

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.21

0.0

2.1

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.5

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.21

0.0

2.1

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection

0.00

0.21

0.0

3.2

—

(3011648) Oxygen content in Venous blood

0.00

0.21

0.0

24.2

—

11.8

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

2.1

—

(1616796) Gas panel - Central venous blood

0.00

0.21

0.0

5.1

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

0.21

0.0

1.3

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.21

0.0

1.7

—

(40768443) Skin Pathology biopsy report

0.00

0.21

0.0

1.1

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.21

0.0

19.1

—

74.1

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3001604) Monocytes [#/volume] in Blood

314

1.17

0.20

6.0

8.7

0.6

e9/l

0.20

256

(3006315) Basophils [#/volume] in Blood

314

1.17

0.20

6.0

8.7

0.0

e9/l

0.09

257

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.7

—

3.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

138

1.21

0.20

3.9

2.8

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.17

0.19

1.3

2.1

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.26

0.19

9.7

22.3

1.0

1.1

mg/l

—

(3016879) Cocaine [Presence] in Urine

1.21

0.19

1.3

2.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

510

1.21

0.17

14.0

10.6

18.3

22.8

mg/l

0.95

343

(3002582) Erythrocytes [#/volume] in Urine

169

1.18

0.17

4.0

5.5

9.7

29.8

e6/l

0.67

128

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.13

0.16

1.1

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.78

0.16

1.2

1.6

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.76

0.16

1.0

1.9

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

102

1.22

0.16

2.3

—

(3023368) Bacteria identified in Blood by Culture

1.16

0.16

5.0

4.0

—

(3022096) Basophils/100 leukocytes in Blood

298

1.15

0.16

6.3

9.0

0.6

0.27

286

(3019198) Lymphocytes [#/volume] in Blood

329

1.14

0.15

5.9

8.5

2.8

2.5

e9/l

0.39

281

(40768804) Tissue Pathology biopsy report

104

0.84

0.14

1.3

1.7

—

(3013115) Eosinophils [#/volume] in Blood

320

1.13

0.14

6.4

9.5

0.2

e9/l

0.11

271

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

133

1.17

0.13

30.9

16.0

24.1

24.3

mmol/l

0.11

133

(3000991) Gas panel - Venous blood

116

1.15

0.10

6.1

14.8

—

(3011288) Drugs identified in Urine by Screen method

1.15

0.10

1.4

2.7

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.12

0.10

1.0

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

107

1.15

0.09

1.6

1.8

—

(3000764) Benzodiazepines [Presence] in Urine

1.10

0.08

1.3

2.0

—

(3028300) Cannabinoids [Presence] in Urine

1.10

0.08

1.3

2.1

—

(3027944) Amphetamines [Presence] in Urine

1.10

0.08

1.3

2.0

—

(3027008) Opiates [Presence] in Urine

1.10

0.08

1.3

2.0

—

(3006504) Eosinophils/100 leukocytes in Blood

306

1.09

0.08

6.3

8.9

3.2

3.4

0.08

289

(3018010) Neutrophils/100 leukocytes in Blood

316

1.09

0.08

6.1

8.5

44.0

47.3

0.75

303

(3018677) aPTT in Platelet poor plasma by Coagulation assay

0.81

0.07

5.1

6.3

36.1

31.6

—

(3019069) Monocytes/100 leukocytes in Blood

308

1.08

0.06

6.3

8.9

8.3

0.03

295

(46235355) HIV 1 and 2 tests - Meaningful Use set

150

1.09

0.05

2.3

2.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

259

0.94

0.03

3.6

5.9

109.9

110.4

ml/min/173m2

0.03

157

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

543

0.97

0.00

4.6

3.8

—

(3002030) Lymphocytes/100 leukocytes in Blood

327

1.02

0.00

6.2

8.6

39.5

37.5

0.47

316

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

51.3

—

(3000899) Streptococcus pneumoniae Danish serotype 7F IgG Ab [Mass/volume] in Serum

0.00

0.0

2.0

—

1.5

—

(4198724)

0.00

0.0

3.2

—

(3006665) Streptococcus pneumoniae Danish serotype 18C IgG Ab [Mass/volume] in Serum

0.00

0.0

2.0

—

0.7

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

0.0

1.0

—

105.7

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.0

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.2

—

(42869858) Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method

0.00

0.0

1.5

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative

0.00

0.0

1.2

—

(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood

0.00

0.0

5.0

—

1.3

—

(36204187) Streptococcus pneumoniae Danish serotype 4 IgG Ab [Mass/volume] in Serum

0.00

0.0

2.0

—

0.6

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

2.0

—

87.5

—

(21494434) Karyotype in Bone marrow

0.00

0.0

2.0

—

(3041672) Baker's yeast Ab [Presence] in Serum

0.00

0.0

1.2

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.8

—

(36204005) Streptococcus pneumoniae Danish serotype 19F IgG Ab [Mass/volume] in Serum

0.00

0.0

2.0

—

7.8

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative

0.00

0.0

1.6

—

(4034850)

0.00

0.0

8.6

—

(3007302) Hemoglobin [Mass/volume] in Mixed venous blood

0.00

0.0

3.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.4

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

0.0

3.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.0

—

(3032352) Blasts [#/volume] in Cerebral spinal fluid

0.00

0.0

7.0

—

(3013924) Clostridium tetani IgG Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

165.3

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

3.2

—

4.7

—

(44813793)

0.00

0.0

1.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.0

—

(3016031) Almond IgE Ab [Units/volume] in Serum

0.00

0.0

1.2

—

4.4

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3032185) JC virus DNA [#/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

10.6

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3027653) Mycophenolate [Mass/volume] in Serum or Plasma

0.00

0.0

8.8

—

1.8

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.1

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.4

—

(3042733) HLA Ab [Presence] in Serum

0.00

0.0

1.7

—

(4027681)

0.00

0.0

1.1

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.1

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.0

1.4

—

147.9

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

1.1

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

0.0

1.4

—

73.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

2.3

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

3.2

—

9.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

185.2

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(1761868) Lipid panel - Serum or Plasma

0.90

0.00

1.0

1.9

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

(3011048) Pyruvate [Moles/volume] in Blood

0.00

0.0

1.4

—

104.9

—

(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection

0.00

0.0

6.8

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

5.2

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.0

—

(3003752) BK virus DNA [Units/volume] (viral load) in Urine by NAA with probe detection

0.00

0.0

6.8

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.0

1.1

—

(3024471) HLA-A [Type]

0.00

0.0

1.0

—

(3001964) Herpes simplex virus Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma

0.00

0.0

2.0

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

0.0

3.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

10.9

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.2

—

(3014373) Corynebacterium diphtheriae Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

2.8

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

0.0

1.6

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

1.9

—

(3013247) Albumin in CSF/Albumin in Serum or Plasma

0.00

0.0

1.1

—

4.6

—

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

18.6

—

(3024932) HLA-DR beta [Type]

0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_FET_NEWB_COMPLICATIO_PLACEN_CORD_MEMBRANES and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_COMPLICATIO_PLACEN_CORD_MEMBRANES.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_FET_NEWB_COMPLICATIO_PLACEN_CORD_MEMBRANES – Fetus and newborn affected by complications of placenta, cord and membranes

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Fetus and newborn affected by complications of placenta, cord and membranes

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints