Fetus and newborn affected by noxious influences transmitted via placenta or breast milk

P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P04 Cause of death: ICD-10 — P04 2 out of 7 registries used, show all original rules.	35
4. Check minimum number of events None	35
5. Include endpoints None	35
6. Filter based on genotype QC (FinnGen only)	33

Control definitions (FinnGen only)

Control exclude: P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P0[0-4]
Name in latin: Fetus et neonatus influentiis noxiis per placentam sive lac maternum translatis affectus

NAME	P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK
CONTROL_EXCLUDE	P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P04
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P04
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Fetus and newborn affected by noxious influences transmitted via placenta or breast milk based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	3798	1782	2014
Only index persons	1275	630	645
Unadjusted period prevalence (%)
Whole population	0.05	0.05	0.06
Only index persons	0.02	0.02	0.02
Median age at first event (years)
Whole population	0.02	0.00	0.00
Only index persons	0.04	0.07	0.01

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	33	15	18
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	0.04	0.09	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

11.69

3.64

1.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

2.56

1.18

1.7

1.4

—

(3018418) pH of Serum or Plasma

2.15

1.05

6.5

6.0

—

7.41

—

(1761868) Lipid panel - Serum or Plasma

0.00

1.03

0.0

2.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

2.20

0.92

1.2

1.5

—

98.10

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.83

0.0

1.6

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

0.00

0.82

0.0

5.6

—

166.96

—

(36660697) Celiac disease serology panel - Serum

1.82

0.78

1.6

1.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.62

0.63

1.0

1.1

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.62

0.0

1.2

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.62

0.0

1.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

158

1.62

0.62

2.5

2.2

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.62

0.0

6.9

—

2.92

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.62

0.0

1.7

—

321.26

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

118

0.58

0.59

1.6

2.1

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

181

1.58

0.55

17.2

21.3

1.23

mmol/l

0.06

174

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

181

1.58

0.55

14.3

20.1

1.22

1.23

mmol/l

0.15

171

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

1.59

0.54

1.9

5.1

—

(3023368) Bacteria identified in Blood by Culture

1.53

0.49

3.9

6.2

—

(3019150) Specific gravity of Urine by Refractometry

1.59

0.48

8.3

5.7

—

1.02

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

107

1.51

0.47

18.4

16.8

37.26

36.70

g/l

0.13

102

(3005322) IgE [Units/volume] in Serum or Plasma

1.52

0.46

1.4

1.5

126.95

131.98

u/ml

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.77

0.46

2.0

2.3

—

(3026008) Bacteria identified in Urine by Culture

1.52

0.44

3.4

2.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.60

0.43

2.0

2.5

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.42

0.0

1.1

—

179.40

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.42

0.0

18.3

—

0.35

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.42

0.0

1.1

—

(43534046) Estradiol (E2) [Moles/volume] in Serum or Plasma by High sensitivity method

0.00

0.42

0.0

2.6

—

0.11

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.42

0.0

1.3

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.42

0.0

1.8

—

(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum

0.00

0.42

0.0

1.2

—

1.66

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

0.42

0.0

1.6

—

0.92

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

0.59

0.41

4.4

10.2

32.00

31.57

—

(40761511) CBC panel - Blood by Automated count

275

1.63

0.41

9.9

11.7

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

150

1.41

0.37

8.2

6.9

230.83

190.25

u/l

0.57

141

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

305

0.71

0.36

4.6

4.3

—

(3022313) Gas panel - Capillary blood

114

1.38

0.32

7.2

12.4

—

(3044889) 12 lead EKG panel

0.71

0.26

2.1

2.2

—

(36304419) Bacteria [Presence] in Urine

117

1.33

0.26

7.1

6.7

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

128

1.30

0.24

4.0

4.7

39.13

51.89

ug/l

0.30

122

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.22

0.22

2.8

1.7

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.22

0.0

2.7

—

11.27

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.00

0.22

0.0

3.5

—

(3002256) Pathology report gross observation

0.00

0.22

0.0

1.4

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.22

0.0

2.7

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.22

0.0

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.22

0.0

1.3

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.22

0.0

1.1

—

0.74

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.22

0.0

1.5

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.22

0.0

3.4

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.22

0.0

1.0

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.22

0.0

5.2

—

1.46

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.22

0.0

1.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.22

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.22

0.0

3.4

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.22

0.0

2.5

—

27.90

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.22

0.0

1.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.22

0.0

5.3

—

(3018738) Hemoglobin F/Hemoglobin.total in Blood

0.00

0.22

0.0

2.7

—

4.40

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.22

0.0

5.3

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.21

0.0

1.3

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.21

0.0

1.2

—

(3003985) Beta hydroxybutyrate [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.9

—

3.16

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.5

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.20

0.0

1.1

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.20

0.0

22.0

—

(3007164) IgA [Mass/volume] in Serum or Plasma

170

0.79

0.19

2.1

0.93

1.18

g/l

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.18

0.19

31.9

30.1

1.16

1.01

mg/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.29

0.19

10.7

4.4

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.73

0.19

2.2

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

0.75

0.18

9.3

5.4

—

(3015736) pH of Urine

112

1.26

0.18

9.5

4.7

—

6.26

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.25

0.17

2.0

4.8

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

255

1.26

0.16

12.4

13.9

21.48

25.01

u/l

0.74

246

(3031040) Bacteria [#/volume] in Urine by Automated count

174

1.20

0.13

4.5

5.5

—

22.60

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

144

0.85

0.11

13.5

16.1

24.62

24.90

mmol/l

0.24

144

(3044640) Blood type and Crossmatch panel - Blood

1.21

0.11

2.1

5.2

—

(3028626) Oxygen [Partial pressure] in Capillary blood

117

1.18

0.10

7.8

13.3

10.56

9.96

kpa

0.44

112

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.07

0.10

2.8

1.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

227

1.18

0.10

10.3

14.9

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

123

0.85

0.10

3.5

4.1

1.19

1.43

mmol/l

2.33

113

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

123

0.85

0.10

3.5

4.6

4.15

4.24

mmol/l

0.14

117

(3007853) Bacteria identified in Skin by Aerobe culture

1.10

0.09

1.3

2.0

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

122

0.86

0.08

3.5

4.2

2.60

2.55

mmol/l

0.08

115

(3037467) Urinalysis macro (dipstick) panel - Urine

182

0.87

0.08

8.5

6.2

—

(3003694) ABO and Rh group [Type] in Blood

1.08

0.08

1.2

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

132

1.10

0.03

10.3

7.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

127

1.04

0.00

18.1

14.6

1.48

1.43

mmol/l

0.21

121

(3000991) Gas panel - Venous blood

124

0.95

0.00

13.9

14.0

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

131

0.99

0.00

9.8

11.3

23.36

23.37

mmol/l

0.00

131

(40758558) Short blood count panel - Blood

171

0.99

0.00

13.8

13.3

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

305.12

—

(3036035) von Willebrand factor (vWf) Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

110.80

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

17.0

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3013247) Albumin in CSF/Albumin in Serum or Plasma

0.00

0.0

1.0

—

7.32

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.4

—

(3016031) Almond IgE Ab [Units/volume] in Serum

0.00

0.0

1.2

—

3.65

—

(3034368) Herpes virus 6 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3014373) Corynebacterium diphtheriae Ab [Units/volume] in Serum

0.00

0.0

1.8

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3013924) Clostridium tetani IgG Ab [Units/volume] in Serum

0.00

0.0

1.8

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.4

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.0

2.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

428.40

—

(3049233) Organic acids panel - Urine

0.00

0.0

1.2

—

(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

67.40

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.0

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.0

1.1

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.0

1.3

—

76.50

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

8.8

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.0

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

0.0

3.0

—

166.13

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3001186) Copper [Moles/volume] in Serum or Plasma

0.00

0.0

2.2

—

28.74

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3010015) Selenium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.7

—

1.05

—

(3042733) HLA Ab [Presence] in Serum

0.00

-0.00

0.0

2.2

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.3

—

(3024471) HLA-A [Type]

0.00

-0.00

0.0

1.0

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.9

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3041672) Baker's yeast Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

-0.00

0.0

4.4

—

9.57

—

(3022670) pH of Venous cord blood

0.00

-0.00

0.0

1.0

—

(3016273) Islet cell 512 Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay

0.00

-0.00

0.0

1.0

—

145.71

—

(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative

0.00

-0.00

0.0

1.1

—

(3003101) Alpha 1 antitrypsin [Mass/mass] in Stool

0.00

-0.00

0.0

3.1

—

214.57

—

(3017115) Methotrexate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

31.7

—

0.71

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

291

0.98

-0.00

14.8

16.4

17.50

23.02

mg/l

0.73

196

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

2.3

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

-0.00

0.0

9.3

—

10.04

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

7.1

—

7.39

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

-0.00

0.0

9.3

—

4.93

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.8

—

(3024932) HLA-DR beta [Type]

0.00

-0.00

0.0

1.1

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

1.3

—

(3012320) Pathologist interpretation of Cerebral spinal fluid tests

0.00

-0.00

0.0

2.0

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

266

1.07

-0.00

15.1

15.2

49.33

44.73

umol/l

0.47

266

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3040893) Potassium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

4.4

—

4.40

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK – Fetus and newborn affected by noxious influences transmitted via placenta or breast milk

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Fetus and newborn affected by noxious influences transmitted via placenta or breast milk

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints