Fetus and newborn affected by maternal complications of pregnancy

P16_FET_NEWB_MATERN_COMPLICATIO_PREGNAC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P01 Cause of death: ICD-10 — P01 2 out of 7 registries used, show all original rules.	231
4. Check minimum number of events None	231
5. Include endpoints None	231
6. Filter based on genotype QC (FinnGen only)	231

Control definitions (FinnGen only)

Control exclude: P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P0[0-4]
Name in latin: Fetus et neonatus complicationibus graviditatis maternis affectus

NAME	P16_FET_NEWB_MATERN_COMPLICATIO_PREGNAC
CONTROL_EXCLUDE	P16_FET_NEWB_MATERN_FACTO_COMPLICATIO_PREGNAC_LABOUR_DELIV
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P01
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P01
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Fetus and newborn affected by maternal complications of pregnancy based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	19742	9127	10615
Only index persons	7988	3741	4247
Unadjusted period prevalence (%)
Whole population	0.28	0.26	0.30
Only index persons	0.15	0.14	0.16
Median age at first event (years)
Whole population	-	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	231	135	96
Unadjusted period prevalence (%)	0.04	0.05	0.04
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
197: Matched controls
1968

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P01.5

ICD-10 Finland

Fetus and newborn affected by multiple pregnancy

+∞

104.8

P01.10

ICD-10 Finland

Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery

+∞

87.1

P07.3

ICD-10 Finland

Other preterm infants

42.1

84.3

108

Z87.6

ICD-10 Finland

Personal history of certain conditions arising in the perinatal period

13.2

37.1

P07.11

ICD-10 Finland

Other low birth weight 1500-1999 g

31.5

19.3

P59.0

ICD-10 Finland

Neonatal jaundice associated with preterm delivery

12.0

16.4

P07.12

ICD-10 Finland

Other low birth weight 2000-2499 g

14.1

14.9

WX722

NOMESCO Finland

PEEP

8.0

14.4

P39.9

ICD-10 Finland

Infection specific to the perinatal period, unspecified

14.9

11.7

P22.1

ICD-10 Finland

Transient tachypnoea of newborn

7.6

10.8

AA5HE

NOMESCO Finland

Brain ultrasound examination in a child

4.7

10.6

P07.1

ICD-10 Finland

Other low birth weight

38.6

9.1

WW805

NOMESCO Finland

Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse

29.0

8.6

A11JC

ATC

Vitamins, other combinations

23.2

8.1

P05.1

ICD-10 Finland

Small for gestational age

10.0

7.9

P70.4

ICD-10 Finland

Other neonatal hypoglycaemia

7.2

7.8

P07.2

ICD-10 Finland

Extreme immaturity

12.5

7.7

P22.0

ICD-10 Finland

Respiratory distress syndrome of newborn

11.5

7.4

P00.0

ICD-10 Finland

Fetus and newborn affected by maternal hypertensive disorders

+∞

7.3

P03.4

ICD-10 Finland

Fetus and newborn affected by caesarean delivery

+∞

7.3

P01.11

ICD-10 Finland

Fetus and newborn affected by premature rupture of membranes more than 7 days before delivery

+∞

7.3

P27.1

ICD-10 Finland

Bronchopulmonary dysplasia originating in the perinatal period

20.9

7.2

WX882

NOMESCO Finland

High dependency care

2.9

7.0

189

R4110

NOMESCO Finland

Physiotherapy

2.4

6.9

337

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

2.7

6.5

217

P36.90

ICD-10 Finland

Suspected bacterial sepsis of newborn

9.7

6.4

P07.10

ICD-10 Finland

Other low birth weight 1000-1499 g

13.1

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3002582) Erythrocytes [#/volume] in Urine

611

1.59

2.77

4.8

5.3

17.2

25.4

e6/l

0.49

464

(3030467) Casts [#/volume] in Urine by Automated count

573

1.57

2.62

4.1

5.1

0.3

e6/l

0.05

429

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

100

2.09

2.28

1.6

1.5

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

100

2.09

2.28

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

635

1.51

2.26

5.7

5.6

—

(3000850) Epithelial cells [#/volume] in Urine

399

1.57

2.16

3.9

4.0

7.1

7.2

e6/l

0.02

351

(36304419) Bacteria [Presence] in Urine

581

1.46

1.88

4.2

5.0

—

(3026820) Hemoglobin [Mass/volume] in Venous cord blood

4.23

1.83

1.0

147.4

163.4

g/l

—

(3022670) pH of Venous cord blood

2.82

1.81

1.0

—

(3032080) INR in Blood by Coagulation assay

384

0.58

1.75

2.8

5.0

1.1

inr

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

556

1.43

1.67

12.2

12.6

1.4

1.0

mmol/l

0.73

389

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

142

0.41

1.58

1.7

1.4

—

(3026782) Osmolality of Urine

390

1.47

1.58

2.8

3.8

545.8

575.6

mosm/kgh2o

0.30

338

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

2.16

1.58

1.0

162.5

166.5

g/l

0.39

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

1.54

0.0

2.3

—

13.8

—

(3013336) Amino acids [Identifier] in Serum or Plasma

0.00

1.53

0.0

2.2

—

(3018095) Leukocytes [#/volume] in Urine

715

1.37

1.50

6.0

6.2

73.3

47.0

e6/l

0.22

478

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

386

1.45

1.48

3.8

4.6

1.7

2.1

e6/l

0.17

228

(3024891) Influenza virus A+B Ag [Presence] in Specimen

134

1.71

1.45

1.4

1.5

—

(3020891) Body temperature

0.00

1.34

0.0

8.1

—

(3045414) Leukocytes [Presence] in Urine

2.13

1.29

1.6

1.7

—

(3002256) Pathology report gross observation

115

0.42

1.29

2.0

1.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.01

1.24

1.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.98

1.19

1.0

1.2

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

384

1.38

1.18

3.8

4.4

0.3

0.9

e6/l

2.19

225

(3005719) IgG [Mass/volume] in Serum or Plasma

256

0.60

1.18

2.9

5.2

9.0

8.3

g/l

0.40

250

(3000330) Specific gravity of Urine by Test strip

2.04

1.18

1.8

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

845

0.75

1.17

3.2

2.9

1.5

1.4

mmol/l

0.46

796

(3043238) Trisomy 21 risk [Likelihood] in Fetus

2.09

1.16

1.8

1.3

—

(40765089) Chromosome analysis panel - Blood by G-banded

2.09

1.16

1.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

501

0.71

1.12

3.5

2.7

—

(3023368) Bacteria identified in Blood by Culture

316

1.40

1.12

3.4

5.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

378

0.68

1.10

2.2

1.7

—

(3014051) Protein [Presence] in Urine by Test strip

2.22

1.09

1.6

1.8

—

(3017732) Neutrophils [#/volume] in Blood

122

0.48

1.09

4.5

1.7

3.5

4.2

e9/l

—

115

(3022313) Gas panel - Capillary blood

501

1.32

1.06

13.1

12.2

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

131

1.58

1.03

1.7

1.9

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

185

0.57

0.99

1.5

1.2

15.6

18.2

iu/ml

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

2.20

0.98

1.0

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

2.20

0.98

1.6

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.20

0.98

1.0

1.1

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.78

0.98

1.2

2.0

—

(3010015) Selenium [Moles/volume] in Serum or Plasma

0.00

0.98

0.0

2.5

—

1.1

—

(3037121) Protein [Mass/volume] in Urine

125

1.57

0.97

8.4

9.0

0.3

0.4

g/l

0.10

110

(3023511) Choriogonadotropin [Units/volume] in Urine

120

0.49

0.96

1.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

1.92

0.95

1.6

1.2

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

1.92

0.95

1.4

1.3

—

(3005033) Fetal Nuchal fold Thickness US

1.92

0.95

1.6

1.2

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.25

0.94

3.0

1.6

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.85

0.93

1.0

1.2

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

2.10

0.90

1.0

1.1

—

(40758558) Short blood count panel - Blood

702

1.26

0.89

7.9

11.4

—

(3009508) Creatinine [Moles/volume] in Urine

406

0.73

0.88

7.0

5.2

7.0

8.2

mmol/l

0.63

379

(1001926) Buprenorphine [Presence] in Urine by Screen method

166

0.58

0.87

2.2

2.0

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

138

0.56

0.86

5.0

2.3

—

76.2

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

1.73

0.84

1.2

1.1

—

(3028026) IgM [Mass/volume] in Serum or Plasma

211

0.64

0.83

2.6

2.4

0.9

1.0

g/l

0.28

206

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

0.79

0.0

6.1

—

(40768443) Skin Pathology biopsy report

1.84

0.79

1.0

1.1

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.84

0.79

3.0

1.5

—

(3051659) 25-hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

0.00

0.79

0.0

1.6

—

19.7

—

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

0.00

0.79

0.0

1.0

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.79

0.0

3.2

—

1.7

—

(3016879) Cocaine [Presence] in Urine

196

0.64

0.78

2.0

—

(3049233) Organic acids panel - Urine

0.00

0.78

0.0

1.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

135

0.58

0.76

5.4

2.3

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

2.11

0.75

8.2

6.8

31.0

24.2

ug/l

—

(4306422)

2.11

0.75

1.0

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

479

0.78

0.72

3.2

2.5

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

1.94

0.71

1.0

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

1.57

0.70

1.9

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

213

0.68

0.69

1.9

—

(3027008) Opiates [Presence] in Urine

213

0.68

0.69

1.9

—

(4198724)

1.80

0.66

1.4

1.8

—

(3027944) Amphetamines [Presence] in Urine

211

0.69

0.66

1.9

—

(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.68

0.61

7.8

12.2

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

1.59

0.61

1.6

1.2

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.59

0.61

1.6

1.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

1.59

0.61

1.6

1.2

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

1.59

0.61

1.6

1.2

—

(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative

0.00

0.60

0.0

1.1

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

229

0.72

0.59

4.2

15.5

93.2

90.1

0.18

229

(3004716) Salmonella sp identified in Stool by Organism specific culture

176

1.34

0.59

1.3

1.2

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

0.58

0.0

6.3

—

(3021440) Promyelocytes/100 leukocytes in Blood

1.46

0.58

10.9

7.7

0.0

—

(3014007) Fractional oxyhemoglobin in Arterial blood

0.57

20.2

19.8

97.4

95.2

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

0.56

0.57

20.2

19.4

1.1

1.0

—

(3013707) Erythrocyte sedimentation rate by Westergren method

107

1163

0.85

0.57

5.0

4.4

5.2

7.9

mm/h

7.11

100

1076

(3021387) Prolactin [Units/volume] in Serum or Plasma

116

1.41

0.56

1.4

1.6

647.1

366.8

mu/l

0.48

109

(3011288) Drugs identified in Urine by Screen method

158

0.68

0.55

2.5

2.4

—

(3028300) Cannabinoids [Presence] in Urine

213

0.73

0.53

1.9

2.0

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

1.51

0.52

6.5

3.4

3.0

2.9

e9/l

—

(3016038) Potassium [Moles/volume] in Urine

1.51

0.52

2.8

26.5

34.5

mmol/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

1.51

0.52

6.7

3.6

45.7

48.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

627

0.84

0.51

4.4

5.4

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

288

0.78

0.50

3.0

295.7

345.7

nmol/l

0.76

276

(3013115) Eosinophils [#/volume] in Blood

129

1204

1.16

0.50

10.1

12.5

0.2

e9/l

1.96

108

998

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

155

1626

0.86

0.48

8.5

10.1

22.7

24.8

u/l

0.89

148

1560

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

108

997

1.16

0.48

2.0

2.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

296

0.79

0.47

2.8

2.1

—

(3000494) Fungus identified in Specimen by Culture

164

0.72

0.47

1.4

1.8

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.41

0.47

1.3

2.6

5.3

5.1

pmol/l

0.19

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

148

1.31

0.45

1.4

1.5

—

(42528717) Cashew nut recombinant (rAna o) 3 IgE Ab [Units/volume] in Serum

1.38

0.44

1.4

1.3

12.1

5.2

u/ml

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.65

0.43

1.8

1.3

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.63

0.43

1.8

1.2

—

(3010813) Leukocytes [#/volume] in Blood

205

2096

0.80

0.43

18.1

19.0

7.1

e9/l

0.03

198

1981

(3022621) pH of Urine by Test strip

1.45

0.42

1.6

2.0

—

(3017181) Myelocytes/100 leukocytes in Blood

105

1.35

0.42

10.9

7.6

1.0

0.4

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

1.39

0.42

5.9

6.3

2.8

2.6

ug/l

—

(3012516) Albumin [Mass/volume] in Urine

138

0.71

0.42

3.9

47.2

243.3

mg/l

—

108

(3032641) Amino acids panel - Urine

0.00

0.41

0.0

1.2

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.41

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.41

0.0

1.0

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.41

0.0

2.3

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

0.41

0.0

1.1

—

(44813793)

1.48

0.40

1.0

—

(3026361) Erythrocytes [#/volume] in Blood

205

2094

0.81

0.40

17.9

19.0

4.6

e12/l

0.98

198

1978

(3007302) Hemoglobin [Mass/volume] in Mixed venous blood

0.00

0.40

0.0

2.3

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.40

0.0

2.6

—

8.6

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.39

0.0

1.3

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

136

0.72

0.39

4.2

2.3

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

152

1.27

0.38

1.4

1.3

301.4

168.9

iu/ml

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

277

0.81

0.38

1.9

1.6

—

(42870588) Differential panel, method unspecified - Blood

100

931

1.13

0.38

10.4

12.3

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

1.30

0.37

1.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

101

942

1.13

0.37

14.6

16.1

1.2

mmol/l

0.94

880

(3020393) Adenovirus Ag [Presence] in Stool

1.28

0.36

1.4

2.3

—

(40761535) Cells panel - Urine sediment

0.65

0.36

15.8

3.9

—

(3052851) Hemolysis interference index of Serum or Plasma

0.65

0.36

2.4

3.6

—

(3007461) Platelets [#/volume] in Blood

205

2091

0.82

0.36

18.0

19.1

284.8

274.6

e9/l

1.21

198

1985

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

641

1.13

0.34

1.7

1.9

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

0.67

0.33

17.2

19.2

0.6

0.7

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

1.31

0.33

2.3

1.8

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

132

0.75

0.33

1.8

1.4

—

(3048689) Calprotectin [Mass/mass] in Stool

419

0.86

0.32

2.2

3.3

53.0

76.4

ug/g

0.68

333

(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection

1.28

0.32

5.3

5.7

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

919

1.11

0.32

14.2

17.8

1.3

1.2

mmol/l

1.42

877

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

218

0.81

0.32

2.6

5.6

39.1

1191.3

ng/l

—

134

(40768797) Stomach Pathology biopsy report

131

0.75

0.32

1.3

1.6

—

(3021901) Oxygen saturation in Capillary blood

1.36

0.31

8.7

11.5

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

181

1858

0.88

0.31

12.1

12.8

21.0

24.1

mg/l

0.59

131

1265

(3006315) Basophils [#/volume] in Blood

123

1170

1.11

0.30

9.9

11.2

0.0

e9/l

0.39

101

947

(3026008) Bacteria identified in Urine by Culture

452

1.13

0.30

2.3

—

(3035350) Ketones [Presence] in Urine by Test strip

745

1.11

0.29

3.6

3.9

0.0

estimate

—

122

(3003694) ABO and Rh group [Type] in Blood

601

0.89

0.29

1.6

—

(3001604) Monocytes [#/volume] in Blood

123

1172

1.10

0.29

9.9

11.2

0.6

e9/l

0.50

101

949

(3037467) Urinalysis macro (dipstick) panel - Urine

113

1073

1.10

0.28

6.0

4.6

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

117

0.76

0.28

1.2

1.8

2.4

mmol/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

130

1244

1.10

0.28

11.2

13.6

3.3

3.4

e9/l

0.26

106

1014

(3035933) Granulocytes/100 leukocytes in Blood

1.26

0.28

1.1

1.4

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.24

0.27

2.0

1.3

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

1.28

0.26

1.2

1.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

829

0.91

0.25

9.0

6.4

116.1

114.1

ml/min/173m2

0.27

495

(3025018) Bordetella pertussis Ab [Titer] in Serum

1.19

0.25

1.6

1.1

—

(3023520) Reticulocytes [#/volume] in Blood

222

0.84

0.24

3.1

7.0

49.3

65.7

e9/l

1.27

142

(3000991) Gas panel - Venous blood

482

0.89

0.24

10.1

13.9

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.18

0.24

2.8

1.3

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.29

0.24

1.1

1.0

—

(3019150) Specific gravity of Urine by Refractometry

378

0.88

0.24

3.7

3.5

1.0

kg/l

0.31

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

189

0.83

0.23

2.0

2.5

9.0

68.9

ng/l

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

1.32

0.23

2.0

2.8

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

887

0.92

0.23

1.7

1.9

3.5

u/ml

0.69

142

(3025159) Blasts/100 leukocytes in Blood

1.25

0.23

12.3

7.7

0.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

421

1.12

0.23

3.0

4.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

744

1.09

0.23

5.2

5.7

0.0

estimate

0.00

127

(3002032) Base excess in Venous blood by calculation

521

0.90

0.23

8.8

13.4

0.7

0.9

mmol/l

0.16

396

(4035726)

0.74

0.23

2.6

2.2

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

945

0.92

0.21

2.5

2.2

5.3

mmol/l

0.10

851

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.19

0.21

1.6

1.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

462

1.10

0.21

2.8

3.6

—

(3002619) Bacteria identified in Specimen by Culture

0.00

0.21

0.0

1.4

—

(3020047) Haemophilus influenzae B Ab [Mass/volume] in Serum

0.00

0.21

0.0

1.4

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

0.21

0.0

1.0

—

108.6

—

(3014038) Collagen crosslinked N-telopeptide [Moles/volume] in Urine

0.00

0.21

0.0

3.1

—

(3041672) Baker's yeast Ab [Presence] in Serum

0.00

0.21

0.0

1.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(4010399)

1.25

0.21

1.2

1.5

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

208

0.85

0.21

2.4

2.2

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

1.17

0.21

1.0

1.3

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

1.17

0.21

2.0

2.7

—

(3028772) Osteocalcin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

2.2

—

(3009261) Glucose [Presence] in Urine by Test strip

748

1.08

0.20

3.7

3.9

0.0

estimate

0.00

125

(3008401) Mugwort IgE Ab [Units/volume] in Serum

193

1.15

0.20

1.1

1.3

0.4

0.8

u/ml

0.45

143

(3003888) Timothy IgE Ab [Units/volume] in Serum

193

1.15

0.20

1.1

1.3

5.8

6.7

u/ml

0.07

149

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.20

0.0

1.1

—

(21494262) English walnut recombinant (rJug r) 3 IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.0

—

1.5

—

(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.0

—

311.9

—

(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum

165

0.84

0.20

2.6

2.2

427.3

174.9

u/ml

—

(3007164) IgA [Mass/volume] in Serum or Plasma

861

0.93

0.19

1.8

1.5

1.4

g/l

0.24

444

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.18

0.19

1.2

1.3

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

100

1.21

0.18

1.2

1.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.21

0.18

1.7

—

(40760892) CBC W Ordered Manual Differential panel - Blood

359

1.10

0.18

5.8

5.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

119

1.19

0.18

1.6

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

205

0.87

0.18

2.4

2.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

319

0.90

0.18

2.5

1.8

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.73

0.17

2.6

2.3

—

(3042936) Bacteria identified in Isolate by Culture

196

1.13

0.17

2.1

—

(3000492) Spirometry study

101

1.20

0.17

1.7

1.4

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

266

0.89

0.16

3.1

4.4

316.8

348.8

u/l

0.07

260

(36660697) Celiac disease serology panel - Serum

389

0.91

0.16

1.3

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

542

0.92

0.16

7.8

11.1

37.2

37.4

g/l

0.08

520

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.78

0.16

1.5

1.2

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.77

0.16

4.0

5.5

104.2

93.9

—

(3022145) Colonoscopy Study observation

0.75

0.16

1.7

1.5

—

(3025941) Bacteria identified in Stool by Culture

1.16

0.15

1.1

1.3

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

1.16

0.15

1.8

2.1

—

(44790047)

0.79

0.15

2.6

2.4

—

(44790048)

0.79

0.15

2.6

2.4

—

(44790049)

0.79

0.15

2.6

2.4

—

(44806118)

0.79

0.15

2.6

2.4

—

(1761868) Lipid panel - Serum or Plasma

243

0.89

0.14

2.2

1.8

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

118

0.84

0.14

2.2

1.9

—

(40768804) Tissue Pathology biopsy report

325

0.91

0.14

1.9

1.7

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

100

0.79

0.14

2.4

2.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

497

0.93

0.13

3.4

3.5

—

(3009542) Hematocrit [Volume Fraction] of Blood

195

1924

1.08

0.13

14.4

18.5

39.3

38.4

1.76

175

1727

(3013512) EKG study

172

1.11

0.11

2.2

2.6

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

211

1.10

0.11

1.1

1.3

2.7

u/ml

0.00

145

(3016244) Insulin [Units/volume] in Serum or Plasma

105

1.15

0.11

2.6

3.2

18.1

23.0

mu/l

0.21

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

167

0.89

0.11

2.4

2.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

289

0.93

0.10

1.0

1.1

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.14

0.10

1.6

1.8

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.06

0.09

1.8

1.6

—

(3029937) Albumin [Presence] in Urine by Test strip

361

1.06

0.09

4.0

3.9

0.0

estimate

—

124

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

302

1.07

0.09

3.1

8.0

1.3

2.7

mg/l

0.95

225

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.80

0.08

1.4

1.2

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

123

0.89

0.08

1.0

1.1

14.1

9.0

u/ml

—

(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum

0.85

0.08

1.5

1.4

5.5

29.1

u/ml

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

1.07

0.07

2.3

2.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

149

1469

1.04

0.07

3.8

3.7

2.1

mu/l

0.21

137

1377

(3019198) Lymphocytes [#/volume] in Blood

122

1199

1.04

0.07

10.0

11.2

2.8

2.5

e9/l

0.71

103

1006

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.07

0.07

3.7

2.4

—

(40761536) Microorganisms panel - Urine sediment

118

1.11

0.07

2.9

3.5

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.88

0.07

1.3

3.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.85

0.07

1.1

2.1

—

(3044640) Blood type and Crossmatch panel - Blood

473

1.05

0.07

3.3

4.9

—

(3015736) pH of Urine

602

1.04

0.06

3.6

3.8

—

(3002385) Erythrocyte distribution width [Ratio]

180

1816

0.96

0.06

17.3

19.1

13.4

13.2

1.16

175

1791

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

100

0.90

0.06

2.2

2.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

284

0.94

0.06

2.1

2.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

291

0.96

0.04

2.3

1.9

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

512

0.97

0.04

2.8

2.1

—

(3020779) Urea [Moles/volume] in Serum or Plasma

331

0.96

0.04

17.6

16.3

4.8

5.0

mmol/l

0.12

323

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

511

0.97

0.03

2.4

3.4

2.7

mg/l

0.10

460

(3035637) Corticotropin [Mass/volume] in Plasma

118

0.93

0.03

1.5

1.8

—

(3044889) 12 lead EKG panel

639

0.98

0.02

2.6

2.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

132

1329

0.98

0.02

3.4

3.3

14.6

14.4

pmol/l

0.40

116

1212

(40761511) CBC panel - Blood by Automated count

181

1818

0.98

0.02

9.7

9.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

338

0.97

0.02

4.2

3.4

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

1.08

0.02

14.2

14.0

22.3

23.1

mmol/l

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

117

0.94

0.02

2.3

2.1

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

322

1.03

0.02

1.8

1.6

107.8

97.2

pmol/l

0.79

164

(3009214) Lutropin [Units/volume] in Serum or Plasma

163

1.05

0.01

2.2

2.4

5.7

5.3

u/l

0.14

104

(3028707) Methadone [Presence] in Urine by Screen method

104

0.96

0.00

2.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

244

0.98

0.00

2.5

2.2

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

142

0.98

0.00

1.9

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

340

1.00

0.00

2.6

2.3

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

760

1.00

0.00

4.3

3.3

34.3

36.7

mmol/mol

1.46

716

(3010726) Horse dander IgE Ab [Units/volume] in Serum

195

1.03

0.00

1.2

0.3

3.7

u/ml

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

146

1.03

0.00

1.5

1.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

163

0.98

0.00

1.2

—

(3006598) pH of Arterial cord blood

145

1.04

0.00

1.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

196

1955

1.01

0.00

4.1

3.9

—

(3021589) Normoblasts [#/volume] in Blood

113

1134

0.99

0.00

11.6

13.1

0.0

e9/l

0.51

845

(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(42868691) Thyroxine (T4) free [Moles/volume] in Serum or Plasma by Dialysis

0.00

0.0

1.7

—

14.8

—

(40759040) C peptide [Moles/volume] in Serum or Plasma --post meal

0.00

0.0

1.2

—

1.0

—

(40761995) Spermatozoa Progressive [#/volume] in Semen

0.00

0.0

1.0

—

(3022907) Direct antiglobulin test.polyspecific reagent [Presence] on Red Blood Cells

0.00

0.0

2.8

—

(3045684) Alkaline phosphatase.other fractions [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.0

—

8.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.89

0.00

1.5

5.7

—

(3016228) CD19 cells/100 cells in Blood

0.00

0.0

4.5

—

14.7

—

(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen

0.00

0.0

2.0

—

(3035400) Alkaline phosphatase.liver [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.0

—

112.0

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(21494814) CD8 cells/100 lymphocytes in Specimen

0.00

0.0

4.3

—

(4146454)

0.00

0.0

4.7

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.92

0.00

2.0

1.8

—

(3043410) Blood group antigens tested for on Red Blood Cells

0.00

0.0

1.6

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.86

0.00

2.4

4.8

24.8

25.2

umol/l

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.4

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.98

0.00

1.4

1.2

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.2

—

4.9

—

(3034037) Hematocrit [Volume Fraction] of Mixed venous blood

0.00

0.0

20.8

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.5

—

13.2

—

(3013862) HLA-DP [Type]

0.00

0.0

1.0

—

(42528615) Etanercept [Mass/volume] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

1.9

—

(40760409) HLA-A [Type] by High resolution

0.00

0.0

1.0

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.99

0.00

1.9

2.1

—

(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen

0.00

0.0

5.2

—

(3044290) Cell count panel - Cerebral spinal fluid

0.99

0.00

2.1

6.2

—

(723473) SARS-CoV-2 (COVID-19) IgA Ab [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.1

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.0

1.3

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.5

—

(36305790) Ustekinumab [Mass/volume] in Serum or Plasma by Immunoassay

0.00

0.0

6.6

—

4.5

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

1.7

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3013931) Oligosaccharides [Presence] in Urine

0.00

0.0

1.0

—

(3012441) Differential panel - Pleural fluid

0.00

0.0

1.6

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

2.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.3

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

2.6

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(46236302) HLA-C [Type] by High resolution typing

0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

1.2

—

(3019779) Phenytoin [Moles/volume] in Serum or Plasma

0.00

0.0

14.2

—

39.4

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.98

0.00

1.4

1.2

58.8

78.6

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.99

0.00

1.0

1.1

—

(40760410) HLA-B [Type] by High resolution

0.00

0.0

1.0

—

(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma

0.00

0.0

1.6

—

(3019225) pH of Specimen

0.94

0.00

13.2

4.3

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

1.00

0.00

1.0

1.1

—

9.1

—

(40763791) Oxygen content in Venous blood by calculation

0.00

0.0

2.2

—

16.5

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.97

0.00

1.8

1.4

1.1

1.2

g/l

—

(40765096) Chromosome analysis panel by Banding

0.00

0.0

1.4

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

0.91

0.00

2.3

5.8

261.8

391.1

mg/l

—

(40763590) HLA-DQ beta [Type]

0.00

0.0

1.0

—

(3003129) Base excess in Capillary blood by calculation

0.00

0.0

3.0

—

0.9

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(723474) SARS-CoV-2 (COVID-19) IgG Ab [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_FET_NEWB_MATERN_COMPLICATIO_PREGNAC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_MATERN_COMPLICATIO_PREGNAC.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_FET_NEWB_MATERN_COMPLICATIO_PREGNAC – Fetus and newborn affected by maternal complications of pregnancy

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Fetus and newborn affected by maternal complications of pregnancy

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints