No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
2454 |
4. Check minimum number of eventsNone |
2454 |
5. Include endpointsNone |
2454 |
6. Filter based on genotype QC (FinnGen only) |
2454 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 24311 | 15031 | 9164 |
Only index persons | 23622 | 14761 | 8861 |
Unadjusted period prevalence (%) | |||
Whole population | 0.36 | 0.43 | 0.26 |
Only index persons | 0.47 | 0.54 | 0.34 |
Median age at first event (years) | |||
Whole population | 25.52 | 25.62 | 25.31 |
Only index persons | 25.68 | 25.74 | 25.59 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 2454 | 1874 | 580 |
Unadjusted period prevalence (%) | 0.55 | 0.64 | 0.26 |
Median age at first event (years) | 28.14 | 27.24 | 31.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2015
- Matched controls
- 20149
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH and mortality.
Females
No dataMales
Parameter | HR [95% CI] | p-value |
---|---|---|
K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH | 1.312 [0.96, 1.79] | 0.089 |
Birth year | 0.984 [0.97, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 83 out of 7004 males with K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH died.
Mortality risk
Mortality risk for people of age
years, who have K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH.N-year risk | Females | Males |
---|---|---|
1 | No data | 0.197% |
5 | No data | 1.455% |
10 | No data | 3.469% |
15 | No data | 6.725% |
20 | No data | 11.429% |
Relationships between endpoints
↥Index endpoint: K11_MAXIL_MOLAR_FAILED_ERUPT_OBSTRUCTION_TOOTH – Impacted maxillary molar
GWS hits: -